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8 results on '"Nizza, Jael"'

1. Guidelines for the management of diabetic ketoacidosis (DKA) have been poorly adopted and implemented, resulting in a lack of improvement in outcomes

Author

Philip, Nevil Chackalaparambil, primary, Hallum, Abigail, additional, Abraham, Anu, additional, Skaria, Maria, additional, Rengarajan, Lakshmi, additional, Solomon, Alexander, additional, Onder, Canay, additional, Falowo, Dolu, additional, Nizza, Jael, additional, Kinnear, Katherine, additional, and Raghavan, Rajeev, additional

Published
2024
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3. A Quality Improvement initiative to assess differences of diabetic ketoacidosis (DKA) management across hospitals in the United Kingdom

Author

Dalzell, Joseph, primary, Skaria, Maria, additional, Kauser-Malik, Saima, additional, Raghavan, Rajeev, additional, Soghal, Shamanth, additional, Tabasum, Maria, additional, Ahmed, Nabeel, additional, Nizza, Jael, additional, Acharya, Jayashekara, additional, Saraf, Sanjay, additional, and Dekode, Team, additional

Published
2023
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6. Is Nerve Electrophysiology a Robust Primary Endpoint in Clinical Trials of Treatments for Diabetic Peripheral Neuropathy?

Author

Al-Bazz, Dalal Y., primary, Nelson, Andrew J., additional, Burgess, Jamie, additional, Petropoulos, Ioannis N., additional, Nizza, Jael, additional, Marshall, Anne, additional, Brown, Emily, additional, Cuthbertson, Daniel J., additional, Marshall, Andrew G., additional, Malik, Rayaz A., additional, and Alam, Uazman, additional

Published
2022
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7. Clinical Characteristics of COVID-19 Patients in a Regional Population With Diabetes Mellitus: The ACCREDIT Study

Author

Llanera, Daniel Kevin, primary, Wilmington, Rebekah, additional, Shoo, Haika, additional, Lisboa, Paulo, additional, Jarman, Ian, additional, Wong, Stephanie, additional, Nizza, Jael, additional, Sharma, Dushyant, additional, Kalathil, Dhanya, additional, Rajeev, Surya, additional, Williams, Scott, additional, Yadav, Rahul, additional, Qureshi, Zubair, additional, Narayanan, Ram Prakash, additional, Furlong, Niall, additional, Westall, Sam, additional, and Nair, Sunil, additional

Published
2022
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8. Clinical Characteristics of COVID-19 Patients in a Regional Population with Diabetes Mellitus: The ACCREDIT Study

Author

Llanera, Daniel Kevin, Wilmington, Rebekah, Shoo, Haika, Lisboa, Paulo, Jarman, Ian, Wong, Stephanie, Nizza, Jael, Sharma, Dushyant, Kalathil, Dhanya, Rajeev, Surya, Williams, Scott, Yadav, Rahul, Qureshi, Zubair, Narayanan, Ram Prakash, Furlong, Niall, Westall, Sam, and Nair, Sunil

Subjects
QA75, Blood Glucose, Male, Endocrinology, Diabetes and Metabolism, Diseases of the endocrine glands. Clinical endocrinology, Endocrinology, RA0421, Humans, risk factors, Receptors, Immunologic, QA, Nutrition, Aged, Retrospective Studies, Original Research, Aged, 80 and over, Glycated Hemoglobin, diabetes, SARS-CoV-2, Age Factors, COVID-19, Middle Aged, RC648-665, Prognosis, mortality, United Kingdom, Hospitalization, Survival Rate, Diabetes Mellitus, Type 2, Female, observational study, CRP, RA, Biomarkers, Follow-Up Studies
Abstract

ObjectiveTo identify clinical and biochemical characteristics associated with 7- & 30-day mortality and intensive care admission amongst diabetes patients admitted with COVID-19.Research Design and MethodsWe conducted a cohort study collecting data from medical notes of hospitalised people with diabetes and COVID-19 in 7 hospitals within the Mersey-Cheshire region from 1 January to 30 June 2020. We also explored the impact on inpatient diabetes team resources. Univariate and multivariate logistic regression analyses were performed and optimised by splitting the dataset into a training, test, and validation sets, developing a robust predictive model for the primary outcome.ResultsWe analyzed data from 1004 diabetes patients (mean age 74.1 (± 12.6) years, predominantly men 60.7%). 45% belonged to the most deprived population quintile in the UK. Median BMI was 27.6 (IQR 23.9-32.4) kg/m2. The primary outcome (7-day mortality) occurred in 24%, increasing to 33% by day 30. Approximately one in ten patients required insulin infusion (9.8%). In univariate analyses, patients with type 2 diabetes had a higher risk of 7-day mortality [p < 0.05, OR 2.52 (1.06, 5.98)]. Patients requiring insulin infusion had a lower risk of death [p = 0.02, OR 0.5 (0.28, 0.9)]. CKD in younger patients (ConclusionsHigher CRP and advanced age were associated with and predictive of death by day 7. However, BMI, presence of diabetes complications, and glycaemic control were not. A high proportion of these patients required insulin infusion warranting increased input from the inpatient diabetes teams.

Published
2021

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