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236 results on '"Niven J"'

1. Predictors of COVID-19 Anxiety in UK University Students

Author

Chelidoni, O., Berry, C., Easterbrook, M. J., Chapman, L., Banerjee, R., Valex, S., and Niven, J. E.

Abstract

The current research aimed to evaluate UK student mental health during the first 4 months of the COVID-19 pandemic. Specifically, we were interested in exploring factors that contribute to students' anxiety levels about COVID-19. Demographics, mental health symptomatology and well-being-related variables were tested as predictors of COVID-19 anxiety. A cross-sectional online survey was completed by 1,164 UK university students (71.8% females). Measures included self-reported data on stress, social phobia, anxiety, depression, psychotic-like experiences, hopefulness, group membership, social identity, belonging, loneliness, COVID-19 related variables and demographics. The majority of participants were between 18 and 24 years old (92.2%), White British (57.9%) and in the first or second year of their course study (63.12%). A series of multiple linear regressions revealed that being female, experiencing more stress and anxiety, and greater worry about COVID-19 and its effects on social relationships were significant in explaining students' pandemic-related anxiety. Students' level of pandemic-related anxiety was independent of ethnicity, socioeconomic background and pre-existing mental health problems. Worrying about the future was the most common pandemic-related stressor, but it was not a significant predictor of COVID-19 anxiety. Our findings are in line with previous findings that females and students experiencing more stress have been disproportionately affected by the COVID-19 pandemic. Our findings could inform the delivery of targeted stress-management interventions that might prove beneficial for student wellbeing.

Published
2023
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2. Comparison of Langevin and Markov channel noise models for neuronal signal generation

Author

Sengupta, B., Laughlin, S. B., and Niven, J. E.

Subjects
Quantitative Biology - Neurons and Cognition
Abstract

The stochastic opening and closing of voltage-gated ion channels produces noise in neurons. The effect of this noise on the neuronal performance has been modelled using either approximate or Langevin model, based on stochastic differential equations or an exact model, based on a Markov process model of channel gating. Yet whether the Langevin model accurately reproduces the channel noise produced by the Markov model remains unclear. Here we present a comparison between Langevin and Markov models of channel noise in neurons using single compartment Hodgkin-Huxley models containing either $Na^{+}$ and $K^{+}$, or only $K^{+}$ voltage-gated ion channels. The performance of the Langevin and Markov models was quantified over a range of stimulus statistics, membrane areas and channel numbers. We find that in comparison to the Markov model, the Langevin model underestimates the noise contributed by voltage-gated ion channels, overestimating information rates for both spiking and non-spiking membranes. Even with increasing numbers of channels the difference between the two models persists. This suggests that the Langevin model may not be suitable for accurately simulating channel noise in neurons, even in simulations with large numbers of ion channels.

Published
2009
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5. The effect of antenatal lifestyle advice for women who are overweight or obese on secondary measures of neonatal body composition: the LIMIT randomised trial

Author

Dodd, J M, Deussen, A R, Mohamad, I, Rifas-Shiman, S L, Yelland, L N, Louise, J, McPhee, A J, Grivell, R M, Owens, J A, Gillman, M W, Robinson, J S, Turnbull, D, Crowther, C, Wittert, G, Moran, L, Cramp, C, ewman, A, Kannieappian, L, Hendrijanto, S, Kelsey, M, Beaumont, J, Danz, C, Koch, J, Webber, A, Holst, C, Zhang, S, Ball, V, Ball, K, Salehi, N, Bartley, R, Stafford-Green, R, Ophel, S, Cooney, M, Szmeja, M, hort, A, Melrose, A, Han, S, Chapple, L, Svigos, J, Bhatia, V, Manton, N, McGavigan, J, Bryce, R, Coppi, S, Fanning, C, Hannah, G, Ignacio, M, Pollard, H, Schmidt, F, Shinners, Y, Dekker, G, Kennedy-Andrews, S, Beaven, R, Niven, J, Burgen, S, Dalton, J, Dewhurst, N, Forst, L, Mugg, V, Will, C, Stone, H, Wilkinson, C, Purcell, H, Wood, J, Press, D, Ralph, K, Donleavy, S, Seager, S, Gately, F, Jolly, A, Lahnstein, L, Harding, S, Daw, K, Hedges, M, and Fraser-Trumble, R

Published
2016
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6. Antenatal dietary and lifestyle advice for women who are overweight or obese and the effect on fetal growth and adiposity: the LIMIT randomised trial

Author

Grivell, R M, Yelland, L N, Deussen, A, Crowther, C A, Dodd, J M, Turnbull, D, McPhee, A, Gillman, M, Wittert, G, Owens, J A, Robinson, J S, Moran, L, Cramp, C, Newman, A, Kannieappan, L, Hendrijanto, S, Kelsey, M, Beaumont, J, Danz, C, Koch, J, Webber, A, Holst, C, Robinson, K, Zhang, S, Ball, V, Ball, K, Deussen, H, Salehi, N, Bartley, R, Stafford-Green, R, Ophel, S, Cooney, M, Szmeja, M, Short, A, Melrose, A, Han, S, Mohamad, I, Chapple, L, Earl, R, Staehr, C, Parange, N, Barreto, M, McGavigan, J, Bryce, R, Coppi, S, Fanning, C, Hannah, G, Ignacio, M, Pollard, H, Schmidt, F, Shinners, Y, Dekker, G, Kennedy-Andrews, S, Beaven, R, Niven, J, Burgen, S, Dalton, J, Dewhurst, N, Forst, L, Mugg, V, Will, C, Stone, H, Wilkinson, C, Purcell, H, Wood, J, Press, D, Ralph, K, Donleavy, S, Seager, S, Gately, F, Jolly, A, Lahnstein, L, Harding, S, Daw, K, Hedges, M, and Fraser-Trumble, R

Published
2016
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16. Macroautophagy in Endogenous Processing of Self- and Pathogen-Derived Antigens for MHC Class II Presentation

Author

Duraes, F. V., Niven, J., Dubrot, J., Hugues, S., and Gannage, M.

Subjects
CD4-positive T-lymphocytes, MHC class II, antigen presentation/processing, macroautophagy, tolerance mechanisms
Abstract

Although autophagy is a process that has been studied for several years its link with antigen presentation and T cell immunity has only recently emerged. Autophagy, which means "self-eating," is important to maintain cell homeostasis and refers to a collection of mechanisms that delivers intracellular material for degradation into lysosomes. Among them, macroautophagy pathway has many implications in different biological processes, including innate and adaptive immunity. In particular, macroautophagy can provide a substantial source of intracellular antigens for loading onto MHC class II molecules using the alternative MHC class II pathway. Through autophagosomes, endogenous self-antigens as well as antigens derived from intracellular pathogens can be delivered to MHC class II compartment and presented to CD4(+) T cells. The pathway will, therefore, impact both peripheral T cell tolerance and the pathogen specific immune response. This review will describe the contribution of autophagy to intracellular presentation of endogenous self- or pathogen-derived antigens via MHC class II and its consequences on CD4(+) T cell responses.

Published
2015

19. The Parkes-MIT-NRAO Radio Surveys

Author

Niven J. Tasker, Ann Savage, A. E. Vaughan, and Alan E. Wright

Subjects
Physics, Radio telescope, Sky, Hubble space telescope, media_common.quotation_subject, Astronomy, Flux, Optical identification, Declination, media_common
Abstract

During 1990, the Parkes radio telescope made a new, deep survey of the southern sky at 4850 MHz (the PMN Survey: see e.g. Griffith and Wright, 1993; Wright et al., 1994). The declination coverage of the survey was from δ = −87° to +10°. The flux limit of the survey was around 30 mJy, although dependent on declination. This survey increased the number of known, southern radio sources by a factor of about 6 to over 65,000.

Published
1996
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30. A head restraint device for vestibular studies

Author

Carroll, W, Lowery, C. A, and Niven, J. I

Subjects
Biotechnology
Abstract

Head restraint device based on vacuum bladder technique for use in vestibular studies

Published
1967

36. Visual illusions of movement

Author

Graybiel, A, Niven, J. I, and Whiteside, T. C. D

Subjects
Biosciences
Abstract

Visual illusions related to involuntary eye movement

Published
1963

40. SHORT NOTES.

Author

Donnelly, B. G., Acland, Clemence M., Siegfried, W. R., Macpherson, D. W. K., Brooke, R. K., Mackie Niven, C. K., Mackie Niven, J. P. M., Niven, C. K., Niven, J. P. M., Clancey, P. A., Skead, D. M., Steyn, P., Courtenay-Latimer, M., Quickelberge, C. D., Winterbottom, J. M., Goodfellow, C. F., and Comins, D. M.

Published
1966
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46. Outside JEB.

Author

Fudge, Douglas, Stecyk, Jonathan A. W., Bonser, Richard H. C., Niven, J. E., and Dow, Julian A. T.

Subjects
BIOLOGICAL research, NEMATOCYSTS, ANTIOXIDANTS, SLED dogs, BLUEBERRIES, ANIMAL migration, PHYSIOLOGY
Abstract

The article presents abstracts of biological research. They include "Nanosecond-scale kinetics of nematocyst discharge," "Total antioxidant power in sled dogs supplemented with blueberries and the comparison of blood parameters associated with exercise," and "Simple rules guide dragonfly migration."

Published
2006

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