Search

Your search keyword '"Niu, Xiuyun"' showing total 5 results
Start Over Author "Niu, Xiuyun"
5 results on '"Niu, Xiuyun"'

1. Fluorescent Carbon Dots as Nanosensors for Monitoring and Imaging Fe3+ and [HPO4]2– Ions

Author

Lin Li, Yuxia Li, Ruirong Liu, Niu Xiuyun, Yanmei Yan, Kaixin Xie, Qiaoling Liu, and Borong Ren

Subjects
chemistry.chemical_compound, chemistry, Thiourea, Nanosensor, Inorganic chemistry, chemistry.chemical_element, General Materials Science, Nitrogen, Fluorescence, Sulfur, Carbon, Hydrothermal circulation, Ion
Abstract

Nitrogen(N) and sulfur(S) codoped carbon dots (N/S-CDs) are facilely developed by a one-pot hydrothermal process from thiourea and o-phenylenediamine as carbon precursors. The as-fabricated N/S-CDs...

Published
2020

2. Carbon dots for lysosome targeting and imaging of lysosomal pH and Cys/Hcy in living cells

Author

Ying Zhao, Yan Zhang, Lin Li, Shiyou Lv, Qing He, Boru Yang, Kaixin Xie, Qiaoling Liu, and Niu Xiuyun

Subjects
Homocysteine, Fluorescence assay, chemistry.chemical_element, Hydrogen-Ion Concentration, Fluorescence, Photoinduced electron transfer, Carbon, chemistry.chemical_compound, symbols.namesake, medicine.anatomical_structure, Spectrometry, Fluorescence, chemistry, Stokes shift, Lysosome, symbols, medicine, Biophysics, Humans, General Materials Science, Cysteine, Lysosomes, Fluorescent Dyes
Abstract

The abnormal concentrations of both biothiols and pH in lysosomes are seriously related to many major diseases, such as Parkinson's and Alzheimer's diseases. Up to now, there are few reports that clearly illustrate the relationship between lysosomal pH and biothiols via fluorescence assay. Herein, novel carbon dots (Scy-CDs) are prepared with good water dispersibility and excellent photostability, and a large Stokes shift of 106 nm is exhibited under an excitation wavelength of 450 nm. The remarkable pH-dependent behavior of Scy-CDs is presented with the fluorescence quenching based on the donor-excited photoinduced electron transfer (d-PET) process. The pKa value is 5.30, which is in good agreement with the range of the normal and abnormal lysosomal pH. Upon the addition of cysteine (Cys) or homocysteine (Hcy), the d-PET process is effectively inhibited with fluorescence recovery totally. The significant co-localization of Scy-CDs with Lyso-Tracker Deep Red in HEp-2 cells and the Pearson correlation coefficient 0.88 strongly suggest that the Scy-CDs can target lysosomal pH and Cys/Hcy in living cells.

Published
2020

5. Fluorescent Carbon Dots as Nanosensors for Monitoring and Imaging Fe3+ and [HPO4]2– Ions.

Author

Liu, Qiaoling, Niu, Xiuyun, Xie, Kaixin, Yan, Yanmei, Ren, Borong, Liu, Ruirong, Li, Yuxia, and Li, Lin

Abstract

Nitrogen-(N) and sulfur-(S) codoped carbon dots (N/S-CDs) are facilely developed by a one-pot hydrothermal process from thiourea and o-phenylenediamine as carbon precursors. The as-fabricated N/S-CDs reveal a high quantum yield of 26% and a large Stokes shift up to 106 nm under the excitation of 450 nm with good water dispersibility as well as antiphotobleaching. With addition of Fe3+, fluorescence quenching happens with a good linearity within 0.3–70 μM and a low detection limit of 0.19 μM. However, the quenched fluorescence could be rapidly recovered with the addition of monohydrogen phosphate ([HPO4]2–) due to formation of the stable complex [Fe-(HPO4)]+ by a competitive reaction between the N/S-CDs-Fe3+ complex and [HPO4]2–, a good linearity is in the range of 0.3–60 μM with a low detection limit of 0.27 μM. Thus, a significant "on–off–on" fluorescence response is performed with obvious color change from yellow-dark brown-yellow. In addition, the practical application and the confocal microscopic images all suggest that the N/S-CDs could target both Fe3+ and [HPO4]2– in living cells, implying that the N/S-CDs possess the diverse applications for Fe3+ and [HPO4]2– recognitions in biomedical fields. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results