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1. Writing Case Reports Can Improve Seven Components in Clinical Reasoning

Author

Nishizawa T, Ishizuka K, Otsuka Y, Nakanishi T, Kawashima A, Miyagami T, and Yamashita S

Subjects
case reports, clinical reasoning, diagnostic excellence, Medicine (General), R5-920
Abstract

Toshinori Nishizawa,1,2 Kosuke Ishizuka,3 Yuki Otsuka,4 Toshiyuki Nakanishi,5 Akira Kawashima,6 Taiju Miyagami,7 Shun Yamashita8,9 1Department of General Internal Medicine, St Luke’s International Hospital, Tokyo, Japan; 2Department of Global Health Promotion, Tokyo Medical and Dental University, Tokyo, Japan; 3Department of General Medicine, Yokohama City University School of Medicine, Kanagawa, Japan; 4Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; 5Department of Emergency and General Medicine, Nerima Hikarigaoka Hospital, Tokyo, Japan; 6Department of General Internal Medicine, National Center for Global Health and Medicine, Tokyo, Japan; 7Department of General Medicine, Faculty of Medicine, Juntendo University, Tokyo, Japan; 8Department of General Medicine, Saga University Hospital, Saga, Japan; 9Education and Research Center for Community Medicine, Faculty of Medicine, Saga University, Saga, JapanCorrespondence: Kosuke Ishizuka, Department of General Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan, Tel +81-45-787-2800, Fax +81-45-350-2728, Email e103007c@yokohama-cu.ac.jpAbstract: Case reports provide scientific knowledge and opportunities for new clinical research. However, it is estimated that less than 5% of cases presented by Japanese generalists at academic conferences are published due to various barriers such as the complex process of writing articles, conducting literature searches, the significant time required, the reluctance to write in English, and the challenge of selecting appropriate journals for publication. Therefore, the purpose of this opinion paper is to provide clinicians with practical tips for writing case reports that promote diagnostic excellence. In recent years, clinical practitioners have been striving for diagnostic excellence and optimal methods to accurately and comprehensively understand the patient’s condition. To write a case report, it is essential to be mindful of the elements of diagnostic excellence and consider the quality of the diagnostic reasoning process. We (the authors) are seven academic generalists who are members of the Japanese Society of Hospital General Medicine (JSHGM) – Junior Doctors Association, with a median of 7 years after graduation and extensive experience publishing case reports in international peer-reviewed journals. We conducted a narrative review and discussed ways to write case reports to promote diagnostic excellence, leveraging our unique perspectives as academic generalists. Our review did not identify any reports addressing the critical points in writing case reports that embody diagnostic excellence. Therefore, this report proposes a methodology that describes the process involved in writing diagnostic excellence-promoting case reports and provides an overview of the lessons learned. Based on our review and discussion, we explain the essential points for promoting diagnostic excellence through case reports categorized into seven components of clinical reasoning. These strategies are useful in daily clinical practice and instrumental in promoting diagnostic excellence through case reports.Keywords: case reports, clinical reasoning, diagnostic excellence

Published
2024

3. Rotational movement analysis based on Fourier-rectangular function transform for cylindrical plasma.

Author

Nishimura, D., Fujisawa, A., Yamasaki, K., Nagashima, Y., Moon, C., Nishizawa, T., Kobayashi, T.-K., Kobayashi, T., Shimizu, A., Tokuzawa, T., and Ido, T.

Subjects
CYLINDRICAL plasmas, STELLAR oscillations, PLASMA dynamics
Abstract

This article presents a method to estimate the rotational velocity of a cylindrical plasma from its two-dimensional images by an extended use of the Fourier-rectangular function transform, which was proposed to analyze the structure and dynamics of a cylindrical plasma [K. Yamasaki e t a l., J. Appl. Phys. 126 , 043304 (2019)]. The proposed method is applied to tomography images of plasmas produced in a linear cylindrical device and succeeds in obtaining the radial distribution of rotational velocity and its fluctuations, providing an interesting finding, that is, the existence of flow modulation associated with m = 1 mode fluctuations. [ABSTRACT FROM AUTHOR]

Published
2023
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5. Development of an Aerosol Assimilation System Using a Global Non‐Hydrostatic Model, a 2‐Dimensional Variational Method, and Multiple Satellite‐Based Aerosol Products.

Author

Goto, D., Nishizawa, T., Uchida, J., Yumimoto, K., Jin, Y., Higurashi, A., Shimizu, A., Sugata, S., Yashiro, H., Hayasaki, M., Dai, T., Cheng, Y., and Tanimoto, H.

Subjects
*AIR pollution, *GEOSTATIONARY satellites, *PARTICULATE matter, *AEROSOLS, *ATMOSPHERIC models
Abstract

The computational balance between the model grid resolution and the complexity of the data assimilation technique is essential for accurate aerosol forecasting and obtaining aerosol reanalysis data sets. This study aimed to develop a high‐resolution aerosol assimilation system. A 2‐dimensional variational method (2DVar) was implemented in a non‐hydrostatic icosahedral atmospheric model (NICAM). This new model (NICAM/2DVar), with a global grid size of 56 km, assimilated the observed aerosol optical depth (AOD) that is estimated by combining multiple products of geostationary and polar‐orbital satellites. The model results were evaluated against ground‐based AOD observations on a global scale. They exhibited higher correlations, lower uncertainties, and lower biases than those obtained without the 2DVar. The model also reproduced the observed surface aerosols (PM2.5) mass concentrations, especially in Kyushu, Japan. This occurred because the satellite‐estimated AODs over ocean close to air pollution sources were obtained for many occasions. The correlation coefficient values against the PM2.5 observations increased from 0.44 to 0.65 compared to the results without the 2DVar. The impact of the 2DVar on the forecast results was investigated, and the forecast values for 2–3 days were improved. Because satellite‐retrieved AODs are often lacking over land owing to retrieval difficulties, the use of ground‐based AODs in assimilations is essential for precise processing the of aerosol reanalysis data sets. The computational cost with the use of the 2DVar was only 0.6% more than that without its use. Thus, aerosol assimilation using the NICAM/2DVar can be realistically extended to finer grid sizes. Plain Language Summary: High‐resolution models and data assimilation techniques should be used to obtain more accurate aerosol distributions. We combined a high‐resolution model and an assimilation method at a low computational cost. We also integrated multiple aerosol satellite products. The new procedure successfully reproduced the aerosol observations. The results were significantly better when observations for multiple grids and times were available. Surface measurements on land, for which satellites often lack aerosol signals, are helpful. Key Points: Combined geostationary and polar orbital satellite aerosol products were assimilatedThe aerosol assimilation results improved with increasing spatiotemporal coverage of the observationsEven though the column‐integrated aerosol optical depth was assimilated, surface aerosol (PM2.5) concentration improved [ABSTRACT FROM AUTHOR]

Published
2024
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7. Usefulness of CT Image Quantitative Analysis for Predicting the Onset of Drug-Induced Lung Injury in Chemotherapy for Elderly Lung Cancer

Author

Shimizu, T., primary, Nakagawa, Y., additional, Asai, Y., additional, Nishizawa, T., additional, Iida, Y., additional, Nomoto, M., additional, Nakamoto, T., additional, Miyamoto, I., additional, Kusahana, R., additional, Nakayama, R., additional, Tanaka, R., additional, Ono, M., additional, Mizuno, Y., additional, Tsujino, I., additional, and Gon, Y., additional

Published
2024
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9. A Single-Center Retrospective Observational Study Evaluating the Favorable Predictive Factors for the Disease Control Time of Treatment with Tocilizumab in Patients of Rheumatoid Arthritis

Author

Ishii N, Shimizu T, Ishiura Y, Amuro H, Nishizawa T, Tamaki T, and Nomura S

Subjects
rheumatoid arthritis, tocilizumab, c-reactive protein, platelet large cell ratio, disease control time, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract

Nobuyasu Ishii, Toshiki Shimizu, Yoshihisa Ishiura, Hideki Amuro, Tohru Nishizawa, Takeshi Tamaki, Shosaku Nomura First Department of Internal Medicine, Kansai Medical University, Moriguchi-City, Osaka, 570-8507, JapanCorrespondence: Toshiki ShimizuFirst Department of Internal Medicine, Kansai Medical University, 10-15 Fumizono-cho, Moriguchi-City, Osaka, 570-8507, JapanTel + 81-6-6992-1001Fax + 81-6-6992-1066Email shimizto@takii.kmu.ac.jpBackground: Tocilizumab (TCZ) is humanized monoclonal antibody against the interleukin-6 (IL-6) and receptor that has prominent efficacy for the treatment of rheumatoid arthritis (RA). We conducted a retrospective observational study to determine how long TCZ controls RA.Patients and Methods: We retrospectively reviewed the medical records of RA patients treated with TCZ. The aim of this study was to evaluate the contribution of clinical parameters to disease control time (DCT) in RA patients.Results: Overall, 144 patients were enrolled in the study. The median age of patients was 66 years (range: 34– 85 years). In univariate analysis, DCT was significantly increased in patients who had never received previous biologic disease-modifying anti-rheumatic drugs treatment (P = 0.0064). We also analyzed the contribution of the base line value of C-reactive protein (CRP) to DCT. We divided the patients with RA into two groups according to a cutoff value of 1.000 mg/dl. The median control times were 77.5 months (95% confidence interval [CI]: 44.8–not reached to median) and 34.5 months (95% CI: 17.0– 79.3) for patients with high and low CRP value, respectively. In univariate analysis, DCT was significantly increased in patients with a high CRP value (P = 0.0283). Multivariate analysis clearly revealed that a high baseline CRP value was an independent favorable predictive factor for longer DCT (hazard ratio, 0.608, 95% CI: 0.378– 0.981, P = 0.0416).Conclusion: These data clearly demonstrate that the baseline value of CRP was closely associated with long time DCT in patients of RA treated with TCZ.Keywords: rheumatoid arthritis, tocilizumab, C-reactive protein, platelet large cell ratio, disease control time

Published
2021

10. Estimation of plasma parameter profiles and their derivatives from linear observations by using Gaussian processes

Author

Nishizawa, T, primary, Tokuda, S, additional, Kobayashi, T, additional, Tanaka, K, additional, Funaba, H, additional, Yamada, I, additional, Takemura, Y, additional, Tokuzawa, T, additional, Yasuhara, R, additional, Uehara, H, additional, Ida, K, additional, Takahashi, H, additional, Kawachi, Y, additional, Inagaki, S, additional, Kado, S, additional, Sasaki, M, additional, and Fujisawa, A, additional

Published
2023
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11. Bre1-nucleosome complex (Model II)

Author

Onishi, S., primary, Sato, K., additional, Hamada, K., additional, Nishizawa, T., additional, Nureki, O., additional, Ogata, K., additional, and Sengoku, T., additional

Published
2023
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14. Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X

Author

Pedersen, T, Abramovic, I, Agostinetti, P, Torres, M, Akaslompolo, S, Belloso, J, Aleynikov, P, Aleynikova, K, Alhashimi, M, Ali, A, Allen, N, Alonso, A, Anda, G, Andreeva, T, Angioni, C, Arkhipov, A, Arnold, A, Asad, W, Ascasibar, E, Aumeunier, M, Avramidis, K, Aymerich, E, Baek, S, Bahner, J, Baillod, A, Balden, M, Baldzuhn, J, Ballinger, S, Banduch, M, Bannmann, S, Navarro, A, Barbui, T, Beidler, C, Belafdil, C, Bencze, A, Benndorf, A, Beurskens, M, Biedermann, C, Biletskyi, O, Blackwell, B, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bongiovi, G, Borchardt, M, Borodin, D, Boscary, J, Bosch, H, Bosmann, T, Boswirth, B, Bottger, L, Bottino, A, Bozhenkov, S, Brakel, R, Brandt, C, Brauer, T, Braune, H, Brezinsek, S, Brunner, K, Buller, S, Burhenn, R, Bussiahn, R, Buttenschon, B, Buzas, A, Bykov, V, Calvo, I, Mata, K, Caminal, I, Cannas, B, Cappa, A, Carls, A, Carovani, F, Carr, M, Carralero, D, Carvalho, B, Casas, J, Castano-Bardawil, D, Castejon, F, Chaudhary, N, Chelis, I, Chomiczewska, A, Coenen, J, Cole, M, Cordella, F, Corre, Y, Crombe, K, Cseh, G, Csillag, B, Damm, H, Day, C, de Baar, M, De la Cal, E, Degenkolbe, S, Demby, A, Denk, S, Dhard, C, Di Siena, A, Dinklage, A, Dittmar, T, Dreval, M, Drevlak, M, Drewelow, P, Drews, P, Dunai, D, Edlund, E, Effenberg, F, Ehrke, G, Endler, M, Ennis, D, Escoto, F, Estrada, T, Fable, E, Fahrenkamp, N, Fanni, A, Faustin, J, Fellinger, J, Feng, Y, Figacz, W, Flom, E, Ford, O, Fornal, T, Frerichs, H, Freundt, S, Fuchert, G, Fukuyama, M, Fullenbach, F, Gantenbein, G, Gao, Y, Garcia, K, Regana, J, Garcia-Cortes, I, Gaspar, J, Gates, D, Geiger, J, Geiger, B, Giudicotti, L, Gonzalez, A, Goriaev, A, Gradic, D, Grahl, M, Graves, J, Green, J, Grelier, E, Greuner, H, Gross, S, Grote, H, Groth, M, Gruca, M, Grulke, O, Grun, M, Arnaiz, J, Gunter, S, Haak, V, Haas, M, Hacker, P, Hakola, A, Hallenbert, A, Hammond, K, Han, X, Hansen, S, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hatzky, R, Hawke, J, Hegedus, S, Hein, B, Heinemann, B, Helander, P, Henneberg, S, Hergenhahn, U, Hidalgo, C, Hindenlang, F, Hirsch, M, Hofel, U, Hollfeld, K, Holtz, A, Hopf, D, Hoschen, D, Houry, M, Howard, J, Huang, X, Hubeny, M, Hudson, S, Ida, K, Igitkhanov, Y, Igochine, V, Illy, S, Ionita-Schrittwieser, C, Isobe, M, Jablczynska, M, Jablonski, S, Jagielski, B, Jakubowski, M, van Vuuren, A, Jelonnek, J, Jenko, F, Jensen, T, Jenzsch, H, Junghanns, P, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kandler, M, Kasilov, S, Kazakov, Y, Kennedy, D, Kharwandikar, A, Khokhlov, M, Kiefer, C, Killer, C, Kirschner, A, Kleiber, R, Klinger, T, Klose, S, Knauer, J, Knieps, A, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kontula, J, Kornejew, P, Koschinsky, J, Kozulia, M, Kramer-Flecken, A, Krampitz, R, Krause, M, Krawczyk, N, Kremeyer, T, Krier, L, Kriete, D, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuczynski, M, Kuhner, G, Kumar, A, Kurki-Suonio, T, Kwak, S, Landreman, M, Lang, P, Langenberg, A, Laqua, H, Laube, R, Lazerson, S, Lewerentz, M, Li, C, Liang, Y, Linsmeier, C, Lion, J, Litnovsky, A, Liu, S, Lobsien, J, Loizu, J, Lore, J, Lorenz, A, Losada, U, Louche, F, Lunsford, R, Lutsenko, V, Machielsen, M, Mackel, F, Maisano-Brown, J, Maj, O, Makowski, D, Manduchi, G, Maragkoudakis, E, Marchuk, O, Marsen, S, Martines, E, Martinez-Fernandez, J, Marushchenko, M, Masuzaki, S, Maurer, D, Mayer, M, Mccarthy, K, Mccormack, O, Mcneely, P, Meister, H, Mendelevitch, B, Mendes, S, Merlo, A, Messian, A, Mielczarek, A, Mishchenko, O, Missal, B, Mitteau, R, Moiseenko, V, Mollen, A, Moncada, V, Monnich, T, Morisaki, T, Moseev, D, Motojima, G, Mulas, S, Mulsow, M, Nagel, M, Naujoks, D, Naulin, V, Neelis, T, Neilson, H, Neu, R, Neubauer, O, Neuner, U, Nicolai, D, Nielsen, S, Niemann, H, Nishiza, T, Nishizawa, T, Nuhrenberg, C, Ochoukov, R, Oelmann, J, Offermanns, G, Ogawa, K, Okamura, S, Olmanns, J, Ongena, J, Oosterbeek, J, Otte, M, Pablant, N, Alvarez, N, Pandey, A, Pasch, E, Pavlichenko, R, Pavone, A, Pawelec, E, Pechstein, G, Pelka, G, Perseo, V, Peterson, B, Pilopp, D, Pingel, S, Pisano, F, Plockl, B, Plunk, G, Poloskei, P, Pompe, B, Popov, A, Porkolab, M, Proll, J, Pueschel, M, Puiatti, M, Sitjes, A, Purps, F, Rahbarnia, K, Rasinski, M, Rasmussen, J, Reiman, A, Reimold, F, Reisner, M, Reiter, D, Richou, M, Riedl, R, Riemann, J, Risse, K, Roberg-Clark, G, Rohde, V, Romazanov, J, Rondeshagen, D, Rong, P, Rudischhauser, L, Rummel, T, Rummel, K, Runov, A, Rust, N, Ryc, L, Salembier, P, Salewski, M, Sanchez, E, Satake, S, Satheeswaran, G, Schacht, J, Scharff, E, Schauer, F, Schilling, J, Schlisio, G, Schmid, K, Schmitt, J, Schmitz, O, Schneider, W, Schneider, M, Schneider, P, Schrittwieser, R, Schroder, T, Schroder, M, Schroeder, R, Schweer, B, Schworer, D, Scott, E, Shanahan, B, Sias, G, Sichta, P, Singer, M, Sinha, P, Siplia, S, Slaby, C, Sleczka, M, Smith, H, Smoniewski, J, Sonnendrucker, E, Spolaore, M, Spring, A, Stadler, R, Stanczak, D, Stange, T, Stepanov, I, Stephey, L, Stober, J, Stroth, U, Strumberger, E, Suzuki, C, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Szucs, M, Tabares, F, Tamura, N, Tancetti, A, Tantos, C, Terry, J, Thienpondt, H, Thomsen, H, Thumm, M, Travere, J, Traverso, P, Tretter, J, Trier, E, Mora, H, Tsujimura, T, Turkin, Y, Tykhyi, A, Unterberg, B, van Eeten, P, van Milligen, B, van Schoor, M, Vano, L, Varoutis, S, Vecsei, M, Vela, L, Velasco, J, Vervier, M, Vianello, N, Viebke, H, Vilbrandt, R, Vogel, G, Vogt, N, Volkhausen, C, von Stechow, A, Wagner, F, Wang, E, Wang, H, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wenzel, U, White, A, Wilde, F, Wilms, F, Windisch, T, Winkler, M, Winter, A, Winters, V, Wolf, R, Wright, A, Wurden, G, Xanthopoulos, P, Xu, S, Yamada, H, Yamaguchi, H, Yokoyama, M, Yoshinuma, M, Yu, Q, Zamanov, M, Zanini, M, Zarnstorff, M, Zhang, D, Zhou, S, Zhu, J, Zhu, C, Zilker, M, Zocco, A, Zohm, H, Zoletnik, S, Zsuga, L, Pedersen T. S., Abramovic I., Agostinetti P., Torres M. A., Akaslompolo S., Belloso J. A., Aleynikov P., Aleynikova K., Alhashimi M., Ali A., Allen N., Alonso A., Anda G., Andreeva T., Angioni C., Arkhipov A., Arnold A., Asad W., Ascasibar E., Aumeunier M. -H., Avramidis K., Aymerich E., Baek S. -G., Bahner J., Baillod A., Balden M., Baldzuhn J., Ballinger S., Banduch M., Bannmann S., Navarro A. B., Barbui T., Beidler C., Belafdil C., Bencze A., Benndorf A., Beurskens M., Biedermann C., Biletskyi O., Blackwell B., Blatzheim M., Bluhm T., Bockenhoff D., Bongiovi G., Borchardt M., Borodin D., Boscary J., Bosch H., Bosmann T., Boswirth B., Bottger L., Bottino A., Bozhenkov S., Brakel R., Brandt C., Brauer T., Braune H., Brezinsek S., Brunner K., Buller S., Burhenn R., Bussiahn R., Buttenschon B., Buzas A., Bykov V., Calvo I., Mata K. C., Caminal I., Cannas B., Cappa A., Carls A., Carovani F., Carr M., Carralero D., Carvalho B., Casas J., Castano-Bardawil D., Castejon F., Chaudhary N., Chelis I., Chomiczewska A., Coenen J. W., Cole M., Cordella F., Corre Y., Crombe K., Cseh G., Csillag B., Damm H., Day C., de Baar M., De la Cal E., Degenkolbe S., Demby A., Denk S., Dhard C., Di Siena A., Dinklage A., Dittmar T., Dreval M., Drevlak M., Drewelow P., Drews P., Dunai D., Edlund E., Effenberg F., Ehrke G., Endler M., Ennis D. A., Escoto F. J., Estrada T., Fable E., Fahrenkamp N., Fanni A., Faustin J., Fellinger J., Feng Y., Figacz W., Flom E., Ford O., Fornal T., Frerichs H., Freundt S., Fuchert G., Fukuyama M., Fullenbach F., Gantenbein G., Gao Y., Garcia K., Regana J. M. G., Garcia-Cortes I., Gaspar J., Gates D. A., Geiger J., Geiger B., Giudicotti L., Gonzalez A., Goriaev A., Gradic D., Grahl M., Graves J. P., Green J., Grelier E., Greuner H., Gross S., Grote H., Groth M., Gruca M., Grulke O., Grun M., Arnaiz J. G., Gunter S., Haak V., Haas M., Hacker P., Hakola A., Hallenbert A., Hammond K., Han X., Hansen S. K., Harris J. H., Hartfuss H., Hartmann D., Hathiramani D., Hatzky R., Hawke J., Hegedus S., Hein B., Heinemann B., Helander P., Henneberg S., Hergenhahn U., Hidalgo C., Hindenlang F., Hirsch M., Hofel U., Hollfeld K. P., Holtz A., Hopf D., Hoschen D., Houry M., Howard J., Huang X., Hubeny M., Hudson S., Ida K., Igitkhanov Y., Igochine V., Illy S., Ionita-Schrittwieser C., Isobe M., Jablczynska M., Jablonski S., Jagielski B., Jakubowski M., van Vuuren A. J., Jelonnek J., Jenko F., Jensen T., Jenzsch H., Junghanns P., Kaczmarczyk J., Kallmeyer J., Kamionka U., Kandler M., Kasilov S., Kazakov Y., Kennedy D., Kharwandikar A., Khokhlov M., Kiefer C., Killer C., Kirschner A., Kleiber R., Klinger T., Klose S., Knauer J., Knieps A., Kochl F., Kocsis G., Kolesnichenko Ya. I., Konies A., Konig R., Kontula J., Kornejew P., Koschinsky J., Kozulia M. M., Kramer-Flecken A., Krampitz R., Krause M., Krawczyk N., Kremeyer T., Krier L., Kriete D. M., Krychowiak M., Ksiazek I., Kubkowska M., Kuczynski M., Kuhner G., Kumar A., Kurki-Suonio T., Kwak S., Landreman M., Lang P. T., Langenberg A., Laqua H. P., Laqua H., Laube R., Lazerson S., Lewerentz M., Li C., Liang Y., Linsmeier Ch., Lion J., Litnovsky A., Liu S., Lobsien J., Loizu J., Lore J., Lorenz A., Losada U., Louche F., Lunsford R., Lutsenko V., Machielsen M., Mackel F., Maisano-Brown J., Maj O., Makowski D., Manduchi G., Maragkoudakis E., Marchuk O., Marsen S., Martines E., Martinez-Fernandez J., Marushchenko M., Masuzaki S., Maurer D., Mayer M., McCarthy K. J., McCormack O., McNeely P., Meister H., Mendelevitch B., Mendes S., Merlo A., Messian A., Mielczarek A., Mishchenko O., Missal B., Mitteau R., Moiseenko V. E., Mollen A., Moncada V., Monnich T., Morisaki T., Moseev D., Motojima G., Mulas S., Mulsow M., Nagel M., Naujoks D., Naulin V., Neelis T., Neilson H., Neu R., Neubauer O., Neuner U., Nicolai D., Nielsen S. K., Niemann H., Nishiza T., Nishizawa T., Nuhrenberg C., Ochoukov R., Oelmann J., Offermanns G., Ogawa K., Okamura S., Olmanns J., Ongena J., Oosterbeek J., Otte M., Pablant N., Alvarez N. P., Pandey A., Pasch E., Pavlichenko R., Pavone A., Pawelec E., Pechstein G., Pelka G., Perseo V., Peterson B., Pilopp D., Pingel S., Pisano F., Plockl B., Plunk G., Poloskei P., Pompe B., Popov A., Porkolab M., Proll J., Pueschel M. J., Puiatti M. -E., Sitjes A. P., Purps F., Rahbarnia K., Rasinski M., Rasmussen J., Reiman A., Reimold F., Reisner M., Reiter D., Richou M., Riedl R., Riemann J., Risse K., Roberg-Clark G., Rohde V., Romazanov J., Rondeshagen D., Rong P., Rudischhauser L., Rummel T., Rummel K., Runov A., Rust N., Ryc L., Salembier P., Salewski M., Sanchez E., Satake S., Satheeswaran G., Schacht J., Scharff E., Schauer F., Schilling J., Schlisio G., Schmid K., Schmitt J., Schmitz O., Schneider W., Schneider M., Schneider P., Schrittwieser R., Schroder T., Schroder M., Schroeder R., Schweer B., Schworer D., Scott E., Shanahan B., Sias G., Sichta P., Singer M., Sinha P., Siplia S., Slaby C., Sleczka M., Smith H., Smoniewski J., Sonnendrucker E., Spolaore M., Spring A., Stadler R., Stanczak D., Stange T., Stepanov I., Stephey L., Stober J., Stroth U., Strumberger E., Suzuki C., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Szucs M., Tabares F. L., Tamura N., Tancetti A., Tantos C., Terry J., Thienpondt H., Thomsen H., Thumm M., Travere J. M., Traverso P., Tretter J., Trier E., Mora H. T., Tsujimura T., Turkin Y., Tykhyi A., Unterberg B., van Eeten P., van Milligen B. Ph., van Schoor M., Vano L., Varoutis S., Vecsei M., Vela L., Velasco J. L., Vervier M., Vianello N., Viebke H., Vilbrandt R., Vogel G., Vogt N., Volkhausen C., von Stechow A., Wagner F., Wang E., Wang H., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wenzel U., White A., Wilde F., Wilms F., Windisch T., Winkler M., Winter A., Winters V., Wolf R., Wright A. M., Wurden G. A., Xanthopoulos P., Xu S., Yamada H., Yamaguchi H., Yokoyama M., Yoshinuma M., Yu Q., Zamanov M., Zanini M., Zarnstorff M., Zhang D., Zhou S., Zhu J., Zhu C., Zilker M., Zocco A., Zohm H., Zoletnik S., Zsuga L., Pedersen, T, Abramovic, I, Agostinetti, P, Torres, M, Akaslompolo, S, Belloso, J, Aleynikov, P, Aleynikova, K, Alhashimi, M, Ali, A, Allen, N, Alonso, A, Anda, G, Andreeva, T, Angioni, C, Arkhipov, A, Arnold, A, Asad, W, Ascasibar, E, Aumeunier, M, Avramidis, K, Aymerich, E, Baek, S, Bahner, J, Baillod, A, Balden, M, Baldzuhn, J, Ballinger, S, Banduch, M, Bannmann, S, Navarro, A, Barbui, T, Beidler, C, Belafdil, C, Bencze, A, Benndorf, A, Beurskens, M, Biedermann, C, Biletskyi, O, Blackwell, B, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bongiovi, G, Borchardt, M, Borodin, D, Boscary, J, Bosch, H, Bosmann, T, Boswirth, B, Bottger, L, Bottino, A, Bozhenkov, S, Brakel, R, Brandt, C, Brauer, T, Braune, H, Brezinsek, S, Brunner, K, Buller, S, Burhenn, R, Bussiahn, R, Buttenschon, B, 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S., Abramovic I., Agostinetti P., Torres M. A., Akaslompolo S., Belloso J. A., Aleynikov P., Aleynikova K., Alhashimi M., Ali A., Allen N., Alonso A., Anda G., Andreeva T., Angioni C., Arkhipov A., Arnold A., Asad W., Ascasibar E., Aumeunier M. -H., Avramidis K., Aymerich E., Baek S. -G., Bahner J., Baillod A., Balden M., Baldzuhn J., Ballinger S., Banduch M., Bannmann S., Navarro A. B., Barbui T., Beidler C., Belafdil C., Bencze A., Benndorf A., Beurskens M., Biedermann C., Biletskyi O., Blackwell B., Blatzheim M., Bluhm T., Bockenhoff D., Bongiovi G., Borchardt M., Borodin D., Boscary J., Bosch H., Bosmann T., Boswirth B., Bottger L., Bottino A., Bozhenkov S., Brakel R., Brandt C., Brauer T., Braune H., Brezinsek S., Brunner K., Buller S., Burhenn R., Bussiahn R., Buttenschon B., Buzas A., Bykov V., Calvo I., Mata K. C., Caminal I., Cannas B., Cappa A., Carls A., Carovani F., Carr M., Carralero D., Carvalho B., Casas J., Castano-Bardawil D., Castejon F., Chaudhary N., Chelis I., Chomiczewska A., Coenen J. W., Cole M., Cordella F., Corre Y., Crombe K., Cseh G., Csillag B., Damm H., Day C., de Baar M., De la Cal E., Degenkolbe S., Demby A., Denk S., Dhard C., Di Siena A., Dinklage A., Dittmar T., Dreval M., Drevlak M., Drewelow P., Drews P., Dunai D., Edlund E., Effenberg F., Ehrke G., Endler M., Ennis D. A., Escoto F. J., Estrada T., Fable E., Fahrenkamp N., Fanni A., Faustin J., Fellinger J., Feng Y., Figacz W., Flom E., Ford O., Fornal T., Frerichs H., Freundt S., Fuchert G., Fukuyama M., Fullenbach F., Gantenbein G., Gao Y., Garcia K., Regana J. M. G., Garcia-Cortes I., Gaspar J., Gates D. A., Geiger J., Geiger B., Giudicotti L., Gonzalez A., Goriaev A., Gradic D., Grahl M., Graves J. P., Green J., Grelier E., Greuner H., Gross S., Grote H., Groth M., Gruca M., Grulke O., Grun M., Arnaiz J. G., Gunter S., Haak V., Haas M., Hacker P., Hakola A., Hallenbert A., Hammond K., Han X., Hansen S. K., Harris J. H., Hartfuss H., Hartmann D., Hathiramani D., Hatzky R., Hawke J., Hegedus S., Hein B., Heinemann B., Helander P., Henneberg S., Hergenhahn U., Hidalgo C., Hindenlang F., Hirsch M., Hofel U., Hollfeld K. P., Holtz A., Hopf D., Hoschen D., Houry M., Howard J., Huang X., Hubeny M., Hudson S., Ida K., Igitkhanov Y., Igochine V., Illy S., Ionita-Schrittwieser C., Isobe M., Jablczynska M., Jablonski S., Jagielski B., Jakubowski M., van Vuuren A. J., Jelonnek J., Jenko F., Jensen T., Jenzsch H., Junghanns P., Kaczmarczyk J., Kallmeyer J., Kamionka U., Kandler M., Kasilov S., Kazakov Y., Kennedy D., Kharwandikar A., Khokhlov M., Kiefer C., Killer C., Kirschner A., Kleiber R., Klinger T., Klose S., Knauer J., Knieps A., Kochl F., Kocsis G., Kolesnichenko Ya. I., Konies A., Konig R., Kontula J., Kornejew P., Koschinsky J., Kozulia M. M., Kramer-Flecken A., Krampitz R., Krause M., Krawczyk N., Kremeyer T., Krier L., Kriete D. M., Krychowiak M., Ksiazek I., Kubkowska M., Kuczynski M., Kuhner G., Kumar A., Kurki-Suonio T., Kwak S., Landreman M., Lang P. T., Langenberg A., Laqua H. P., Laqua H., Laube R., Lazerson S., Lewerentz M., Li C., Liang Y., Linsmeier Ch., Lion J., Litnovsky A., Liu S., Lobsien J., Loizu J., Lore J., Lorenz A., Losada U., Louche F., Lunsford R., Lutsenko V., Machielsen M., Mackel F., Maisano-Brown J., Maj O., Makowski D., Manduchi G., Maragkoudakis E., Marchuk O., Marsen S., Martines E., Martinez-Fernandez J., Marushchenko M., Masuzaki S., Maurer D., Mayer M., McCarthy K. J., McCormack O., McNeely P., Meister H., Mendelevitch B., Mendes S., Merlo A., Messian A., Mielczarek A., Mishchenko O., Missal B., Mitteau R., Moiseenko V. E., Mollen A., Moncada V., Monnich T., Morisaki T., Moseev D., Motojima G., Mulas S., Mulsow M., Nagel M., Naujoks D., Naulin V., Neelis T., Neilson H., Neu R., Neubauer O., Neuner U., Nicolai D., Nielsen S. K., Niemann H., Nishiza T., Nishizawa T., Nuhrenberg C., Ochoukov R., Oelmann J., Offermanns G., Ogawa K., Okamura S., Olmanns J., Ongena J., Oosterbeek J., Otte M., Pablant N., Alvarez N. P., Pandey A., Pasch E., Pavlichenko R., Pavone A., Pawelec E., Pechstein G., Pelka G., Perseo V., Peterson B., Pilopp D., Pingel S., Pisano F., Plockl B., Plunk G., Poloskei P., Pompe B., Popov A., Porkolab M., Proll J., Pueschel M. J., Puiatti M. -E., Sitjes A. P., Purps F., Rahbarnia K., Rasinski M., Rasmussen J., Reiman A., Reimold F., Reisner M., Reiter D., Richou M., Riedl R., Riemann J., Risse K., Roberg-Clark G., Rohde V., Romazanov J., Rondeshagen D., Rong P., Rudischhauser L., Rummel T., Rummel K., Runov A., Rust N., Ryc L., Salembier P., Salewski M., Sanchez E., Satake S., Satheeswaran G., Schacht J., Scharff E., Schauer F., Schilling J., Schlisio G., Schmid K., Schmitt J., Schmitz O., Schneider W., Schneider M., Schneider P., Schrittwieser R., Schroder T., Schroder M., Schroeder R., Schweer B., Schworer D., Scott E., Shanahan B., Sias G., Sichta P., Singer M., Sinha P., Siplia S., Slaby C., Sleczka M., Smith H., Smoniewski J., Sonnendrucker E., Spolaore M., Spring A., Stadler R., Stanczak D., Stange T., Stepanov I., Stephey L., Stober J., Stroth U., Strumberger E., Suzuki C., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Szucs M., Tabares F. L., Tamura N., Tancetti A., Tantos C., Terry J., Thienpondt H., Thomsen H., Thumm M., Travere J. M., Traverso P., Tretter J., Trier E., Mora H. T., Tsujimura T., Turkin Y., Tykhyi A., Unterberg B., van Eeten P., van Milligen B. Ph., van Schoor M., Vano L., Varoutis S., Vecsei M., Vela L., Velasco J. L., Vervier M., Vianello N., Viebke H., Vilbrandt R., Vogel G., Vogt N., Volkhausen C., von Stechow A., Wagner F., Wang E., Wang H., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wenzel U., White A., Wilde F., Wilms F., Windisch T., Winkler M., Winter A., Winters V., Wolf R., Wright A. M., Wurden G. A., Xanthopoulos P., Xu S., Yamada H., Yamaguchi H., Yokoyama M., Yoshinuma M., Yu Q., Zamanov M., Zanini M., Zarnstorff M., Zhang D., Zhou S., Zhu J., Zhu C., Zilker M., Zocco A., Zohm H., Zoletnik S., and Zsuga L.

Abstract

We present recent highlights from the most recent operation phases of Wendelstein 7-X, the most advanced stellarator in the world. Stable detachment with good particle exhaust, low impurity content, and energy confinement times exceeding 100 ms, have been maintained for tens of seconds. Pellet fueling allows for plasma phases with reduced ion-temperature-gradient turbulence, and during such phases, the overall confinement is so good (energy confinement times often exceeding 200 ms) that the attained density and temperature profiles would not have been possible in less optimized devices, since they would have had neoclassical transport losses exceeding the heating applied in W7-X. This provides proof that the reduction of neoclassical transport through magnetic field optimization is successful. W7-X plasmas generally show good impurity screening and high plasma purity, but there is evidence of longer impurity confinement times during turbulence-suppressed phases.

Published
2022

15. Non-parametric inference of impurity transport coefficients in the ASDEX Upgrade tokamak

Author

Nishizawa, T, Dux, R, Mcdermott, R, Sciortino, F, Cavedon, M, Schuster, C, Wolfrum, E, Von Toussaint, U, Van Vuuren, A, Cruz-Zabala, D, Cano-Megias, P, Moon, C, Nishizawa T., Dux R., McDermott R. M., Sciortino F., Cavedon M., Schuster C., Wolfrum E., Von Toussaint U., Van Vuuren A. J., Cruz-Zabala D. J., Cano-Megias P., Moon C., Nishizawa, T, Dux, R, Mcdermott, R, Sciortino, F, Cavedon, M, Schuster, C, Wolfrum, E, Von Toussaint, U, Van Vuuren, A, Cruz-Zabala, D, Cano-Megias, P, Moon, C, Nishizawa T., Dux R., McDermott R. M., Sciortino F., Cavedon M., Schuster C., Wolfrum E., Von Toussaint U., Van Vuuren A. J., Cruz-Zabala D. J., Cano-Megias P., and Moon C.

Abstract

We present a non-parametric inference of impurity transport coefficients by using charge exchange recombination spectroscopy measurements of Ne X, Ne VIII, O VIII, and C VI lines. Due to their close atomic numbers, neon, oxygen and carbon impurity ions are assumed to have the same diffusion coefficient D and convection velocity v. Unlike conventional techniques that modulate or perturb the impurity contents, we employ a quasi-stationary plasma with static impurity profiles. Since the ratio of v to D only describes the equilibrated profile of the sum of all impurity charge states, steady-state measurements can still decouple D and v if different charge states are simultaneously observed. We have formulated a non-parametric analysis framework based on the Bayesian probability theory and conducted transport coefficient measurements for a Type III ELMy H-mode plasma at ASDEX Upgrade. The charge exchange reactions with the background neutrals, which are known to affect the impurity charge state balance, are taken into account by introducing additional free parameters. While D at the pedestal is close to the neoclassical level ( < 1 m s-2), a large diffusion coefficient and a strong outward convection are inferred right inside the pedestal top.

Published
2022

16. Physics Exploitation of the new Divertor Thomson Scattering at ASDEX Upgrade

Author

Cavedon, M, Dux, R, Kurzan, B, Bernert, M, Brida, D, Henderson, S, Nishizawa, T, Lunt, T, Pan, O, Reimold, F, Stroth, U, Wischmeier, M, Wu, H, Cavedon M., Dux R., Kurzan B., Bernert M., Brida D., Henderson S., Nishizawa T., Lunt T., Pan O., Reimold F., Stroth U., Wischmeier M., Wu H., Cavedon, M, Dux, R, Kurzan, B, Bernert, M, Brida, D, Henderson, S, Nishizawa, T, Lunt, T, Pan, O, Reimold, F, Stroth, U, Wischmeier, M, Wu, H, Cavedon M., Dux R., Kurzan B., Bernert M., Brida D., Henderson S., Nishizawa T., Lunt T., Pan O., Reimold F., Stroth U., Wischmeier M., and Wu H.

Published
2022

17. Experimental investigation of L- and H-mode detachment via the divertor Thomson scattering at ASDEX Upgrade

Author

Cavedon, M, Kurzan, B, Bernert, M, Brida, D, Dux, R, Griener, M, Henderson, S, Huett, E, Nishizawa, T, Lunt, T, Pan, O, Stroth, U, Wischmeier, M, Wolfrum, E, Cavedon M., Kurzan B., Bernert M., Brida D., Dux R., Griener M., Henderson S., Huett E., Nishizawa T., Lunt T., Pan O., Stroth U., Wischmeier M., Wolfrum E., Cavedon, M, Kurzan, B, Bernert, M, Brida, D, Dux, R, Griener, M, Henderson, S, Huett, E, Nishizawa, T, Lunt, T, Pan, O, Stroth, U, Wischmeier, M, Wolfrum, E, Cavedon M., Kurzan B., Bernert M., Brida D., Dux R., Griener M., Henderson S., Huett E., Nishizawa T., Lunt T., Pan O., Stroth U., Wischmeier M., and Wolfrum E.

Abstract

The capabilities of the newly installed divertor Thomson Scattering (DTS) diagnostic (Kurzan et al 2021 J. Inst. 16 C09012) at ASDEX Upgrade (AUG) have been demonstrated by measuring 2D electron densities n e and temperatures T e from attached to fully detached divertor conditions in L- and H-mode. The collected dataset is a breakthrough for divertor studies at AUG in which such measurements have been so far missing. Besides highlighting the strengths and limits of the DTS system, this work provides confirmations and new insights into detachment physics. The transition between partial and pronounced detachment correlates with a 2D redistribution of the electron density from the inner to the outer divertor in both L- and H-mode. In pronounced detachment, a strong parallel pressure gradient could be confirmed throughout the complete SOL. Finally, measurements of n e and T e of a stable X-point radiator revealed local temperatures as low as 1 eV within the confined plasma, whereas the pressure is shown to be constant on closed field lines.

Published
2022

20. Development of EarthCARE algorithms for the study of clouds, aerosol and radiation

Author

Okamoto, H., Sato, K., and Nishizawa, T.

Abstract

We describe the JAXA algorithms and products from the Earth Clouds Aerosol and Radiation Explorer (EarthCARE). EarthCARE is a joint mission by Japan Aerospace Exploration Agency (JAXA) and the European Space Agency (ESA) to understand clouds, aerosols and radiation. It will carry Doppler cloud profiling radar (CPR), atmospheric high spectral resolution lidar (ATLID), multi-le spectral imager (MSI) and broad band radiometer (BBR) JAXA EarthCARE algorithms have been extended from the algorithms for CloudSat, CALIPSO and MODIS to produce Kyushu (KU) products and JAXA EarthCARE A-train products. Doppler capability of CPR is expected to provide terminal velocity of cloud/precipitation particles and vertical air motion inside clouds. High spectral resolution lidar ATLID provides true backscattering coefficient, extinction coefficient and depolarization ratio. Theoretical studies have indicated that the two-dimensional diagram of lidar ratio and depolarization ratio is essential not only for aerosol components but for retrieving cloud particle shapes and orientations (Okamoto et al., 2019, 2020). Recently developed physical model (Sato et al., 2018) and vectorized physical model (Sato et al., 2019) can be used to take lidar multiple scattering into account for the interpretation of active sensor signals of optically thick clouds. Synergy of new observations with the theoretical improvements enables better estimation of radiative characteristics of cloud/precipitation/aerosol particles.Synergetic ground-based observation systems have been developed to evaluate the EarthCARE algorithms. It consists of Multi-Field-of-view Multiple Scattering Polarization Lidar, high spectral resolution lidar, direct and coherent Doppler lidars and high-sensitivity-cloud radar.&nbsp, The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

Published
2023
Full Text
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21. THE EARTHCARE SATELLITE : The Next Step Forward in Global Measurements of Clouds, Aerosols, Precipitation, and Radiation

Author

Illingworth, A. J., Barker, H. W., Beljaars, A., Ceccaldi, M., Chepfer, H., Clerbaux, N., Cole, J., Delanoë, J., Domenech, C., Donovan, D. P., Fukuda, S., Hirakata, M., Hogan, R. J., Huenerbein, A., Kollias, P., Kubota, T., Nakajima, T., Nakajima, T. Y., Nishizawa, T., Ohno, Y., Okamoto, H., Oki, R., Sato, K., Satoh, M., Shephard, M. W., Velázquez-Blázquez, A., Wandinger, U., Wehr, T., and van Zadelhoff, G.-J.

Published
2015

22. Anti-atherosclerotic effects of sitagliptin in patients with type 2 diabetes mellitus

Author

Omoto S, Taniura T, Nishizawa T, Tamaki T, and Shouzu A,Nomura S

Subjects
Specialties of internal medicine, RC581-951
Abstract

Seitaro Omoto,1 Takehito Taniura,2 Tohru Nishizawa,3 Takeshi Tamaki,3 Akira Shouzu,4 Shosaku Nomura3 1Division of Internal Medicine, Korigaoka Yukeikai Hospital, 2Division of Internal Medicine, Daiwa Hospital, 3First Department of Internal Medicine, Kansai Medical University, 4Division of Internal Medicine, Saiseikai Izuo Hospital, Osaka, Japan Background: Advanced glycation end products, selectins, and adiponectin play important roles in the development of atherosclerosis in individuals with diabetes. Sitagliptin has been shown to reduce the concentration of glycated hemoglobin in diabetic patients. However, its effects on soluble receptor for advanced glycation end products (sRAGEs), selectins, and adiponectin in these patients are poorly understood. This study was conducted to assess the effects of sitagliptin on the circulating levels of sRAGEs, monocyte chemoattractant protein-1 (MCP-1), selectins, and adiponectin in patients with type 2 diabetes. Methods: Diabetic patients eligible for sitagliptin monotherapy or combination therapy (eg, sitagliptin plus a sulfonylurea) were administered sitagliptin (50 mg/day) for 6 months. Levels of soluble P-selectin (sP-selectin), soluble E-selectin (sE-selectin), soluble vascular cell adhesion molecule-1 (sVCAM-1), MCP-1, sRAGEs, and adiponectin were measured by ELISA at baseline and after 3 and 6 months of treatment. Results: At baseline, the levels of MCP-1, sP-selectin, sE-selectin, and sVCAM-1 were higher and the level of adiponectin was lower in diabetic patients than in nondiabetic patients. Sitagliptin therapy for 3 and 6 months significantly reduced plasma levels of sP-selectin, sE-selectin, sVCAM-1, and MCP-1 relative to baseline, while significantly increasing adiponectin levels. sRAGEs did not exhibit a statistical significance, although there was an increasing tendency. Furthermore, the reductions in sP-selectin, sE-selectin, sVCAM-1, and MCP-1 during sitagliptin therapy were significantly greater in responders, defined as patients with a significant increase in adiponectin levels, than in nonresponders. In contrast, responders showed a significant increase in the plasma concentration of sRAGEs. Conclusion: Sitagliptin shows an adiponectin-dependent anti-atherothrombotic effect, which may be beneficial for primary prevention of atherothrombosis, in patients with type 2 diabetes. Keywords: type 2 diabetes mellitus, sitagliptin, sRAGE, selectins, sVCAM-1, adiponectin

Published
2015

26. Determination of the background neutral density from passive Balmer alpha CX emission at the ASDEX Upgrade tokamak

Author

Van Vuuren, A, Bogar, K, Cruz-Zabala, D, Cavedon, M, Cano-Megias, P, Kappatou, A, Dux, R, Schneider, P, Viezzer, E, Nishizawa, T, Garcia-Munoz, M, Van Vuuren A. J., Bogar K., Cruz-Zabala D. J., Cavedon M., Cano-Megias P., Kappatou A., Dux R., Schneider P. A., Viezzer E., Nishizawa T., Garcia-Munoz M., Van Vuuren, A, Bogar, K, Cruz-Zabala, D, Cavedon, M, Cano-Megias, P, Kappatou, A, Dux, R, Schneider, P, Viezzer, E, Nishizawa, T, Garcia-Munoz, M, Van Vuuren A. J., Bogar K., Cruz-Zabala D. J., Cavedon M., Cano-Megias P., Kappatou A., Dux R., Schneider P. A., Viezzer E., Nishizawa T., and Garcia-Munoz M.

Published
2021

27. Linearized spectrum correlation analysis for thermal helium beam diagnostics

Author

Nishizawa, T, Griener, M, Dux, R, Grenfell, G, Wendler, D, Kado, S, Manz, P, Cavedon, M, Nishizawa T., Griener M., Dux R., Grenfell G., Wendler D., Kado S., Manz P., Cavedon M., Nishizawa, T, Griener, M, Dux, R, Grenfell, G, Wendler, D, Kado, S, Manz, P, Cavedon, M, Nishizawa T., Griener M., Dux R., Grenfell G., Wendler D., Kado S., Manz P., and Cavedon M.

Abstract

We introduce a new correlation analysis technique for thermal helium beam (THB) diagnostics. Instead of directly evaluating line ratios from fluctuating time series, we apply arithmetic operations to all available He I lines and construct time series with desired dependencies on the plasma parameters. By cross-correlating those quantities and by evaluating ensemble averages, uncorrelated noise contributions can be removed. Through the synthetic data analysis, we demonstrate that the proposed analysis technique is capable of providing the power spectral densities of meaningful plasma parameters, such as the electron density and the electron temperature, even under low-photon-count conditions. In addition, we have applied this analysis technique to the experimental THB data obtained at the ASDEX Upgrade tokamak and successfully resolved the electron density and temperature fluctuations up to 90 kHz in a reactor relevant high power scenario.

Published
2021

28. Plasma parameter profile inference from limited data utilizing second-order derivative priors and physic-based constraints

Author

Nishizawa, T, Cavedon, M, Dux, R, Reimold, F, Toussaint, U, Nishizawa T., Cavedon M., Dux R., Reimold F., Toussaint U. V., Nishizawa, T, Cavedon, M, Dux, R, Reimold, F, Toussaint, U, Nishizawa T., Cavedon M., Dux R., Reimold F., and Toussaint U. V.

Abstract

A Bayesian framework has been used to improve the quality of inferred plasma parameter profiles. An integrated data analysis allows for coherent combinations of different diagnostics, and Gaussian process regression provides a reliable regularization process and systematic uncertainty estimation. In this paper, we propose a new profile inference framework that utilizes our prior knowledge about plasma physics, along with integrated data analysis and a Gaussian process. In order to facilitate the use of the Markov chain Monte Carlo sampling, we use a Gaussian process to define quantities corresponding to the second derivatives of the profiles. We validate the analysis technique by using a synthetic one-dimensional plasma, in which the transport properties are known and demonstrate that the proposed analysis technique can infer plasma parameter profiles from line-integrated measurements only. Furthermore, we can even infer unknown parameters in our physics models when our physics knowledge on the system is incomplete. This analysis framework is applicable to laboratory plasmas and provides a means to investigate plasma parameters, to which standard diagnostics are not directly sensitive.

Published
2021

35. PTH-bound human PTH1R in complex with Gs (class4)

Author

Kobayashi, K., primary, Kusakizako, T., additional, Miyauchi, H., additional, Tomita, A., additional, Kobayashi, K., additional, Shihoya, W., additional, Yamashita, K., additional, Nishizawa, T., additional, Kato, H.E., additional, and Nureki, O., additional

Published
2022
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36. PTHrP-bound human PTH1R in complex with Gs

Author

Kobayashi, K., primary, Kusakizako, T., additional, Miyauchi, H., additional, Tomita, A., additional, Kobayashi, K., additional, Shihoya, W., additional, Yamashita, K., additional, Nishizawa, T., additional, Kato, H.E., additional, and Nureki, O., additional

Published
2022
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37. Cryo-EM structure of Rhizobium etli MprF

Author

Nishimura, M., primary, Hirano, H., additional, Kobayashi, K., additional, Gill, C.P., additional, Phan, C.N.K., additional, Kise, Y., additional, Kusakizako, T., additional, Yamashita, K., additional, Ito, Y., additional, Roy, H., additional, Nishizawa, T., additional, and Nureki, O., additional

Published
2022
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38. Bayesian inference of particle source and sink in a closed-divertor using Balmer line spectroscopy

Author

Nishizawa, T, Cavedon, M, Reimold, F, Dux, R, Brida, D, Wu, H, Nishizawa T., Cavedon M., Reimold F., Dux R., Brida D., Wu H., Nishizawa, T, Cavedon, M, Reimold, F, Dux, R, Brida, D, Wu, H, Nishizawa T., Cavedon M., Reimold F., Dux R., Brida D., and Wu H.

Abstract

A new analysis technique for Balmer line spectroscopy that enables recombination rate (particle sink) and ionization rate (particle source) inference in a closed divertor configuration is reported. Bayesian inference is employed to systematically utilize all available information from multiple Balmer lines and constrain parameter ranges by using prior knowledge about plasmas. While a closed-divertor facilitates detachment, neutral plugging typically leads to large spatial variations in plasma parameters. A forward model is developed to take into account non-uniformity in the plasma parameters and applied to test data generated by divertor plasma simulations. It is shown that the forward model robustly provides particle source and sink inference over a wide parameter range. In addition, the precision improves as more Balmer lines are resolved simultaneously. The new analysis technique is also applied to an L-mode ASDEX Upgrade plasma in the high-recycling regime. The inferred quantities and their profiles are consistent with the expectations of a high-recycling divertor plasma. The further insight into the detachment physics will be provided by using this new analysis technique.

Published
2020

40. High-heat flux ball-pen probe head in ASDEX-Upgrade

Author

Grenfell, G., Adamek, J., Komm, M., Brida, D., Conway, G. D., Manz, P., Tolias, Panagiotis, Eich, T., Sestak, D., Herrmann, A., Nishizawa, T., Stroth, U., Grenfell, G., Adamek, J., Komm, M., Brida, D., Conway, G. D., Manz, P., Tolias, Panagiotis, Eich, T., Sestak, D., Herrmann, A., Nishizawa, T., and Stroth, U.

Abstract

A new high heat flux ball-pen probe head installed on the midplane manipulator is currently being used in ASDEX-Upgrade (AUG). The probe was designed to withstand high heat fluxes making possible the investigation of the plasma edge under harsh conditions, such as low power H-mode. Composed of seven pins (four Langmuir probes, mounted in two Mach probe pairs, and three ball-pen probes), the new probe head allows us to measure several plasma parameters simultaneously and with high temporal resolution. A novel method to correct the sheath potential dynamically accounting for the total secondary electron emission is introduced together with applications to obtain the electron temperature and plasma potential profiles. The total secondary electron emission yield is obtained from particle in cell simulations in AUG condition and probe realistic impact angle with respect to the magnetic field. Finally, the probe capability to investigate turbulence around the separatrix of AUG is discussed.& nbsp, QC 20220322

Published
2022
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41. Non-parametric inference of impurity transport coefficients in the ASDEX Upgrade tokamak

Author

Universidad de Sevilla. Departamento de Ingeniería Energética, Universidad de Sevilla. FQM402: Ciencias y Tecnologías del Plasma y el Espacio, Nishizawa, T., Dux, R., McDermott, R.M., Sciortino, F., Cavedon, M., Schuster, C., Wolfrum, E., Von Toussaint, U., Van Vuuren, A.Jansen, Cruz Zabala, Diego José, Cano Megías, Pilar, Moon, C., Universidad de Sevilla. Departamento de Ingeniería Energética, Universidad de Sevilla. FQM402: Ciencias y Tecnologías del Plasma y el Espacio, Nishizawa, T., Dux, R., McDermott, R.M., Sciortino, F., Cavedon, M., Schuster, C., Wolfrum, E., Von Toussaint, U., Van Vuuren, A.Jansen, Cruz Zabala, Diego José, Cano Megías, Pilar, and Moon, C.

Abstract

We present a non-parametric inference of impurity transport coefficients by using charge exchange recombination spectroscopy measurements of Ne X, Ne VIII, O VIII, and C VI lines. Due to their close atomic numbers, neon, oxygen and carbon impurity ions are assumed to have the same diffusion coefficient D and convection velocity v. Unlike conventional techniques that modulate or perturb the impurity contents, we employ a quasi-stationary plasma with static impurity profiles. Since the ratio of v to D only describes the equilibrated profile of the sum of all impurity charge states, steady-state measurements can still decouple D and v if different charge states are simultaneously observed. We have formulated a non-parametric analysis framework based on the Bayesian probability theory and conducted transport coefficient measurements for a Type III ELMy H-mode plasma at ASDEX Upgrade. The charge exchange reactions with the background neutrals, which are known to affect the impurity charge state balance, are taken into account by introducing additional free parameters. While D at the pedestal is close to the neoclassical level ( < 1 m s-2), a large diffusion coefficient and a strong outward convection are inferred right inside the pedestal top.

Published
2022

42. Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X

Author

Pedersen, Thomas Sunn, Abramovic, I., Agostinetti, P., Torres, M. Agredano, Äkäslompolo, S., Belloso, J. Alcuson, Aleynikov, P., Aleynikova, K., Alhashimi, M., Ali, A., Allen, N., Alonso, A., Anda, G., Andreeva, T., Angioni, C., Arkhipov, A., Arnold, A., Asad, W., Ascasibar, E., Aumeunier, M. H., Avramidis, K., Aymerich, E., Baek, S. G., Bähner, J., Baillod, A., Balden, M., Baldzuhn, J., Ballinger, S., Banduch, M., Bannmann, S., Navarro, A. Bañón, Barbui, T., Beidler, C., Belafdil, C., Bencze, A., Benndorf, A., Beurskens, M., Biedermann, C., Biletskyi, O., Blackwell, B., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bongiovi, G., Borchardt, M., Borodin, D., Boscary, J., Bosch, H., Bosmann, T., Böswirth, B., Böttger, L., Bottino, A., Bozhenkov, S., Brakel, R., Brandt, C., Bräuer, T., Braune, H., Brezinsek, S., Brunner, K., Buller, S., Burhenn, R., Bussiahn, R., Buttenschön, B., Buzás, A., Bykov, V., Calvo, I., Mata, K. Camacho, Caminal, I., Cannas, B., Cappa, A., Carls, A., Carovani, F., Carr, M., Carralero, D., Carvalho, B., Casas, J., Castano-Bardawil, D., Castejon, F., Chaudhary, N., Chelis, I., Chomiczewska, A., Coenen, J. W., Cole, M., Cordella, F., Corre, Y., Crombe, K., Cseh, G., Csillag, B., Damm, H., Day, C., de Baar, M., De la Cal, E., Degenkolbe, S., Demby, A., Denk, S., Dhard, C., Di Siena, A., Dinklage, A., Dittmar, T., Dreval, M., Drevlak, M., Drewelow, P., Drews, P., Dunai, D., Edlund, E., Effenberg, F., Ehrke, G., Endler, M., Ennis, D. A., Escoto, F. J., Estrada, T., Fable, E., Fahrenkamp, N., Fanni, A., Faustin, J., Fellinger, J., Feng, Y., Figacz, W., Flom, E., Ford, O., Fornal, T., Frerichs, H., Freundt, S., Fuchert, G., Fukuyama, M., Füllenbach, F., Gantenbein, G., Gao, Y., Garcia, K., Regaña, J. M.García, García-Cortés, I., Gaspar, J., Gates, D. A., Geiger, J., Geiger, B., Giudicotti, L., González, A., Goriaev, A., Gradic, D., Grahl, M., Graves, J. P., Green, J., Grelier, E., Greuner, H., Groß, S., Grote, H., Groth, M., Gruca, M., Grulke, O., Grün, M., Arnaiz, J. Guerrero, Günter, S., Haak, V., Haas, M., Hacker, P., Hakola, A., Hallenbert, A., Hammond, K., Han, X., Hansen, S. K., Harris, J. H., Hartfuß, H., Hartmann, D., Hathiramani, D., Hatzky, R., Hawke, J., Hegedus, S., Hein, B., Heinemann, B., Helander, P., Henneberg, S., Hergenhahn, U., Hidalgo, C., Hindenlang, F., Hirsch, M., Höfel, U., Hollfeld, K. P., Holtz, A., Hopf, D., Höschen, D., Houry, M., Howard, J., Huang, X., Hubeny, M., Hudson, S., Ida, K., Igitkhanov, Y., Igochine, V., Illy, S., Ionita-Schrittwieser, C., Isobe, M., Jabłczynska, M., Jablonski, S., Jagielski, B., Jakubowski, M., van Vuuren, A. Jansen, Jelonnek, J., Jenko, F., Jensen, T., Jenzsch, H., Junghanns, P., Kaczmarczyk, J., Kallmeyer, J., Kamionka, U., Kandler, M., Kasilov, S., Kazakov, Y., Kennedy, D., Kharwandikar, A., Khokhlov, M., Kiefer, C., Killer, C., Kirschner, A., Kleiber, R., Klinger, T., Klose, S., Knauer, J., Knieps, A., Köchl, F., Kocsis, G., Kolesnichenko, Ya I., Könies, A., König, R., Kontula, J., Kornejew, P., Koschinsky, J., Kozulia, M. M., Krämer-Flecken, A., Krampitz, R., Krause, M., Krawczyk, N., Kremeyer, T., Krier, L., Kriete, D. M., Krychowiak, M., Ksiazek, I., Kubkowska, M., Kuczynski, M., Kühner, G., Kumar, A., Kurki-Suonio, T., Kwak, S., Landreman, M., Lang, P. T., Langenberg, A., Laqua, H., Laube, R., Lazerson, S., Lewerentz, M., Li, C., Liang, Y., Linsmeier, Ch, Lion, J., Litnovsky, A., Liu, S., Lobsien, J., Loizu, J., Lore, J., Lorenz, A., Losada, U., Louche, F., Lunsford, R., Lutsenko, V., Machielsen, M., Mackel, F., Maisano-Brown, J., Maj, O., Makowski, D., Manduchi, G., Maragkoudakis, E., Marchuk, O., Marsen, S., Martines, E., Martinez-Fernandez, J., Marushchenko, M., Masuzaki, S., Maurer, D., Mayer, M., McCarthy, K. J., McCormack, O., McNeely, P., Meister, H., Mendelevitch, B., Mendes, S., Merlo, A., Messian, A., Mielczarek, A., Mishchenko, O., Missal, B., Mitteau, R., Moiseenko, V. E., Mollen, A., Moncada, V., Mönnich, T., Morisaki, T., Moseev, D., Motojima, G., Mulas, S., Mulsow, M., Nagel, M., Naujoks, D., Naulin, V., Neelis, T., Neilson, H., Neu, R., Neubauer, O., Neuner, U., Nicolai, D., Nielsen, S. K., Niemann, H., Nishiza, T., Nishizawa, T., Nührenberg, C., Ochoukov, R., Oelmann, J., Offermanns, G., Ogawa, K., Okamura, S., Ölmanns, J., Ongena, J., Oosterbeek, J., Otte, M., Pablant, N., Alvarez, N. Panadero, Pandey, A., Pasch, E., Pavlichenko, R., Pavone, A., Pawelec, E., Pechstein, G., Pelka, G., Perseo, V., Peterson, B., Pilopp, D., Pingel, S., Pisano, F., Plöckl, B., Plunk, G., Pölöskei, P., Pompe, B., Popov, A., Porkolab, M., Proll, J., Pueschel, M. J., Puiatti, M. E., Sitjes, A. Puig, Purps, F., Rahbarnia, K., Rasinski, M., Rasmussen, J., Reiman, A., Reimold, F., Reisner, M., Reiter, D., Richou, M., Riedl, R., Riemann, J., Riße, K., Roberg-Clark, G., Rohde, V., Romazanov, J., Rondeshagen, D., Rong, P., Rudischhauser, L., Rummel, T., Rummel, K., Runov, A., Rust, N., Ryc, L., Salembier, P., Salewski, M., Sanchez, E., Satake, S., Satheeswaran, G., Schacht, J., Scharff, E., Schauer, F., Schilling, J., Schlisio, G., Schmid, K., Schmitt, J., Schmitz, O., Schneider, W., Schneider, M., Schneider, P., Schrittwieser, R., Schröder, T., Schröder, M., Schroeder, R., Schweer, B., Schwörer, D., Scott, E., Shanahan, B., Sias, G., Sichta, P., Singer, M., Sinha, P., Sipliä, S., Slaby, C., Sleczka, M., Smith, H., Smoniewski, J., Sonnendrücker, E., Spolaore, M., Spring, A., Stadler, R., Stanczak, D., Stange, T., Stepanov, I., Stephey, L., Stober, J., Stroth, U., Strumberger, E., Suzuki, C., Suzuki, Y., Svensson, J., Szabolics, T., Szepesi, T., Szücs, M., Tabarés, F. L., Tamura, N., Tancetti, A., Tantos, C., Terry, J., Thienpondt, H., Thomsen, H., Thumm, M., Travere, J. M., Traverso, P., Tretter, J., Trier, E., Mora, H. Trimino, Tsujimura, T., Turkin, Y., Tykhyi, A., Unterberg, B., van Eeten, P., van Milligen, B. Ph, van Schoor, M., Vano, L., Varoutis, S., Vecsei, M., Vela, L., Velasco, J. L., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vogel, G., Vogt, N., Volkhausen, C., von Stechow, A., Wagner, F., Wang, E., Wang, H., Warmer, F., Wauters, T., Wegener, L., Wegner, T., Weir, G., Wenzel, U., White, A., Wilde, F., Wilms, F., Windisch, T., Winkler, M., Winter, A., Winters, V., Wolf, R., Wright, A. M., Wurden, G. A., Xanthopoulos, P., Xu, S., Yamada, H., Yamaguchi, H., Yokoyama, M., Yoshinuma, M., Yu, Q., Zamanov, M., Zanini, M., Zarnstorff, M., Zhang, D., Zhou, S., Zhu, J., Zhu, C., Zilker, M., Zocco, A., Zohm, H., Zoletnik, S., Zsuga, L., Pedersen, Thomas Sunn, Abramovic, I., Agostinetti, P., Torres, M. Agredano, Äkäslompolo, S., Belloso, J. Alcuson, Aleynikov, P., Aleynikova, K., Alhashimi, M., Ali, A., Allen, N., Alonso, A., Anda, G., Andreeva, T., Angioni, C., Arkhipov, A., Arnold, A., Asad, W., Ascasibar, E., Aumeunier, M. H., Avramidis, K., Aymerich, E., Baek, S. G., Bähner, J., Baillod, A., Balden, M., Baldzuhn, J., Ballinger, S., Banduch, M., Bannmann, S., Navarro, A. Bañón, Barbui, T., Beidler, C., Belafdil, C., Bencze, A., Benndorf, A., Beurskens, M., Biedermann, C., Biletskyi, O., Blackwell, B., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bongiovi, G., Borchardt, M., Borodin, D., Boscary, J., Bosch, H., Bosmann, T., Böswirth, B., Böttger, L., Bottino, A., Bozhenkov, S., Brakel, R., Brandt, C., Bräuer, T., Braune, H., Brezinsek, S., Brunner, K., Buller, S., Burhenn, R., Bussiahn, R., Buttenschön, B., Buzás, A., Bykov, V., Calvo, I., Mata, K. Camacho, Caminal, I., Cannas, B., Cappa, A., Carls, A., Carovani, F., Carr, M., Carralero, D., Carvalho, B., Casas, J., Castano-Bardawil, D., Castejon, F., Chaudhary, N., Chelis, I., Chomiczewska, A., Coenen, J. W., Cole, M., Cordella, F., Corre, Y., Crombe, K., Cseh, G., Csillag, B., Damm, H., Day, C., de Baar, M., De la Cal, E., Degenkolbe, S., Demby, A., Denk, S., Dhard, C., Di Siena, A., Dinklage, A., Dittmar, T., Dreval, M., Drevlak, M., Drewelow, P., Drews, P., Dunai, D., Edlund, E., Effenberg, F., Ehrke, G., Endler, M., Ennis, D. A., Escoto, F. J., Estrada, T., Fable, E., Fahrenkamp, N., Fanni, A., Faustin, J., Fellinger, J., Feng, Y., Figacz, W., Flom, E., Ford, O., Fornal, T., Frerichs, H., Freundt, S., Fuchert, G., Fukuyama, M., Füllenbach, F., Gantenbein, G., Gao, Y., Garcia, K., Regaña, J. M.García, García-Cortés, I., Gaspar, J., Gates, D. A., Geiger, J., Geiger, B., Giudicotti, L., González, A., Goriaev, A., Gradic, D., Grahl, M., Graves, J. P., Green, J., Grelier, E., Greuner, H., Groß, S., Grote, H., Groth, M., Gruca, M., Grulke, O., Grün, M., Arnaiz, J. Guerrero, Günter, S., Haak, V., Haas, M., Hacker, P., Hakola, A., Hallenbert, A., Hammond, K., Han, X., Hansen, S. K., Harris, J. H., Hartfuß, H., Hartmann, D., Hathiramani, D., Hatzky, R., Hawke, J., Hegedus, S., Hein, B., Heinemann, B., Helander, P., Henneberg, S., Hergenhahn, U., Hidalgo, C., Hindenlang, F., Hirsch, M., Höfel, U., Hollfeld, K. P., Holtz, A., Hopf, D., Höschen, D., Houry, M., Howard, J., Huang, X., Hubeny, M., Hudson, S., Ida, K., Igitkhanov, Y., Igochine, V., Illy, S., Ionita-Schrittwieser, C., Isobe, M., Jabłczynska, M., Jablonski, S., Jagielski, B., Jakubowski, M., van Vuuren, A. Jansen, Jelonnek, J., Jenko, F., Jensen, T., Jenzsch, H., Junghanns, P., Kaczmarczyk, J., Kallmeyer, J., Kamionka, U., Kandler, M., Kasilov, S., Kazakov, Y., Kennedy, D., Kharwandikar, A., Khokhlov, M., Kiefer, C., Killer, C., Kirschner, A., Kleiber, R., Klinger, T., Klose, S., Knauer, J., Knieps, A., Köchl, F., Kocsis, G., Kolesnichenko, Ya I., Könies, A., König, R., Kontula, J., Kornejew, P., Koschinsky, J., Kozulia, M. M., Krämer-Flecken, A., Krampitz, R., Krause, M., Krawczyk, N., Kremeyer, T., Krier, L., Kriete, D. M., Krychowiak, M., Ksiazek, I., Kubkowska, M., Kuczynski, M., Kühner, G., Kumar, A., Kurki-Suonio, T., Kwak, S., Landreman, M., Lang, P. T., Langenberg, A., Laqua, H., Laube, R., Lazerson, S., Lewerentz, M., Li, C., Liang, Y., Linsmeier, Ch, Lion, J., Litnovsky, A., Liu, S., Lobsien, J., Loizu, J., Lore, J., Lorenz, A., Losada, U., Louche, F., Lunsford, R., Lutsenko, V., Machielsen, M., Mackel, F., Maisano-Brown, J., Maj, O., Makowski, D., Manduchi, G., Maragkoudakis, E., Marchuk, O., Marsen, S., Martines, E., Martinez-Fernandez, J., Marushchenko, M., Masuzaki, S., Maurer, D., Mayer, M., McCarthy, K. J., McCormack, O., McNeely, P., Meister, H., Mendelevitch, B., Mendes, S., Merlo, A., Messian, A., Mielczarek, A., Mishchenko, O., Missal, B., Mitteau, R., Moiseenko, V. E., Mollen, A., Moncada, V., Mönnich, T., Morisaki, T., Moseev, D., Motojima, G., Mulas, S., Mulsow, M., Nagel, M., Naujoks, D., Naulin, V., Neelis, T., Neilson, H., Neu, R., Neubauer, O., Neuner, U., Nicolai, D., Nielsen, S. 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Abstract

We present recent highlights from the most recent operation phases of Wendelstein 7-X, the most advanced stellarator in the world. Stable detachment with good particle exhaust, low impurity content, and energy confinement times exceeding 100 ms, have been maintained for tens of seconds. Pellet fueling allows for plasma phases with reduced ion-temperature-gradient turbulence, and during such phases, the overall confinement is so good (energy confinement times often exceeding 200 ms) that the attained density and temperature profiles would not have been possible in less optimized devices, since they would have had neoclassical transport losses exceeding the heating applied in W7-X. This provides proof that the reduction of neoclassical transport through magnetic field optimization is successful. W7-X plasmas generally show good impurity screening and high plasma purity, but there is evidence of longer impurity confinement times during turbulence-suppressed phases.

Published
2022

43. Edge turbulence measurements in L-mode and I-mode at ASDEX Upgrade

Author

Massachusetts Institute of Technology. Plasma Science and Fusion Center, Massachusetts Institute of Technology. Department of Physics, Bielajew, R, Conway, GD, Griener, M, Happel, T, Höfler, K, Howard, NT, Hubbard, AE, McCarthy, W, Molina Cabrera, PA, Nishizawa, T, Rodriguez-Fernandez, P, Silvagni, D, Vanovac, B, Wendler, D, Yoo, C, White, AE, Massachusetts Institute of Technology. Plasma Science and Fusion Center, Massachusetts Institute of Technology. Department of Physics, Bielajew, R, Conway, GD, Griener, M, Happel, T, Höfler, K, Howard, NT, Hubbard, AE, McCarthy, W, Molina Cabrera, PA, Nishizawa, T, Rodriguez-Fernandez, P, Silvagni, D, Vanovac, B, Wendler, D, Yoo, C, and White, AE

Abstract

The I-mode confinement regime is promising for future reactor operation due to high energy confinement without high particle confinement. However, the role of edge turbulence in creating I-mode's beneficial transport properties is still unknown. New measurements of edge turbulence ([Formula: see text]) in L-modes and I-modes at low and high densities at ASDEX Upgrade are presented in this paper. A high radial resolution correlation electron cyclotron emission radiometer measures the broadband turbulence throughout the L-mode and I-mode edge and pedestal. The weakly coherent mode (WCM) is measured in both L-mode and I-mode near the last closed flux surface with Te fluctuation levels of 2.3%–4.2%, with a frequency shift between the two phases related to a deeper Er well in I-mode. An [Formula: see text] phase diagnostic captures a change of the WCM [Formula: see text] phase between L-mode and I-mode from [Formula: see text] to [Formula: see text]. The thermal He beam diagnostic measures a WCM wavenumber range of −0.5 to −1.0 cm−1. A low-frequency edge oscillation (LFEO) appears in the I-mode phase of these discharges and displays coupling to the WCM, but the LFEO does not appear in the L-mode phase. Linear gyrokinetic simulations of the outer core and pedestal top turbulence indicate that while the dominant turbulent modes in the outer core are ion directed and electrostatic, the turbulence becomes increasingly electron directed and electromagnetic with increasing radius. Collisionality is not found to impact characteristics of the L-mode and I-mode edge turbulence with respect to the presence of the WCM; however, the quality of global confinement decreases with collisionality.

Published
2022

44. human NTCP in complex with YN69083 Fab

Author

Park, J.H., primary, Iwamoto, M., additional, Yun, J.H., additional, Uchikubo-Kamo, T., additional, Son, D., additional, Jin, Z., additional, Yoshida, H., additional, Ohki, M., additional, Ishimoto, N., additional, Mizutani, K., additional, Oshima, M., additional, Muramatsu, M., additional, Wakita, T., additional, Shirouzu, M., additional, Liu, K., additional, Uemura, T., additional, Nomura, N., additional, Iwata, S., additional, Watashi, K., additional, Tame, J.R.H., additional, Nishizawa, T., additional, Lee, W., additional, and Park, S.Y., additional

Published
2022
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48. Cryo-EM structure of VCCN1 in detergent

Author

Hagino, T., primary, Kato, T., additional, Kasuya, G., additional, Kobayashi, K., additional, Kusakizako, T., additional, Yamashita, K., additional, Nishizawa, T., additional, and Nureki, O., additional

Published
2022
Full Text
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