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1. Writing Case Reports Can Improve Seven Components in Clinical Reasoning

Author

Nishizawa T, Ishizuka K, Otsuka Y, Nakanishi T, Kawashima A, Miyagami T, and Yamashita S

Subjects
case reports, clinical reasoning, diagnostic excellence, Medicine (General), R5-920
Abstract

Toshinori Nishizawa,1,2 Kosuke Ishizuka,3 Yuki Otsuka,4 Toshiyuki Nakanishi,5 Akira Kawashima,6 Taiju Miyagami,7 Shun Yamashita8,9 1Department of General Internal Medicine, St Luke’s International Hospital, Tokyo, Japan; 2Department of Global Health Promotion, Tokyo Medical and Dental University, Tokyo, Japan; 3Department of General Medicine, Yokohama City University School of Medicine, Kanagawa, Japan; 4Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; 5Department of Emergency and General Medicine, Nerima Hikarigaoka Hospital, Tokyo, Japan; 6Department of General Internal Medicine, National Center for Global Health and Medicine, Tokyo, Japan; 7Department of General Medicine, Faculty of Medicine, Juntendo University, Tokyo, Japan; 8Department of General Medicine, Saga University Hospital, Saga, Japan; 9Education and Research Center for Community Medicine, Faculty of Medicine, Saga University, Saga, JapanCorrespondence: Kosuke Ishizuka, Department of General Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan, Tel +81-45-787-2800, Fax +81-45-350-2728, Email e103007c@yokohama-cu.ac.jpAbstract: Case reports provide scientific knowledge and opportunities for new clinical research. However, it is estimated that less than 5% of cases presented by Japanese generalists at academic conferences are published due to various barriers such as the complex process of writing articles, conducting literature searches, the significant time required, the reluctance to write in English, and the challenge of selecting appropriate journals for publication. Therefore, the purpose of this opinion paper is to provide clinicians with practical tips for writing case reports that promote diagnostic excellence. In recent years, clinical practitioners have been striving for diagnostic excellence and optimal methods to accurately and comprehensively understand the patient’s condition. To write a case report, it is essential to be mindful of the elements of diagnostic excellence and consider the quality of the diagnostic reasoning process. We (the authors) are seven academic generalists who are members of the Japanese Society of Hospital General Medicine (JSHGM) – Junior Doctors Association, with a median of 7 years after graduation and extensive experience publishing case reports in international peer-reviewed journals. We conducted a narrative review and discussed ways to write case reports to promote diagnostic excellence, leveraging our unique perspectives as academic generalists. Our review did not identify any reports addressing the critical points in writing case reports that embody diagnostic excellence. Therefore, this report proposes a methodology that describes the process involved in writing diagnostic excellence-promoting case reports and provides an overview of the lessons learned. Based on our review and discussion, we explain the essential points for promoting diagnostic excellence through case reports categorized into seven components of clinical reasoning. These strategies are useful in daily clinical practice and instrumental in promoting diagnostic excellence through case reports.Keywords: case reports, clinical reasoning, diagnostic excellence

Published
2024

2. A Single-Center Retrospective Observational Study Evaluating the Favorable Predictive Factors for the Disease Control Time of Treatment with Tocilizumab in Patients of Rheumatoid Arthritis

Author

Ishii N, Shimizu T, Ishiura Y, Amuro H, Nishizawa T, Tamaki T, and Nomura S

Subjects
rheumatoid arthritis, tocilizumab, c-reactive protein, platelet large cell ratio, disease control time, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract

Nobuyasu Ishii, Toshiki Shimizu, Yoshihisa Ishiura, Hideki Amuro, Tohru Nishizawa, Takeshi Tamaki, Shosaku Nomura First Department of Internal Medicine, Kansai Medical University, Moriguchi-City, Osaka, 570-8507, JapanCorrespondence: Toshiki ShimizuFirst Department of Internal Medicine, Kansai Medical University, 10-15 Fumizono-cho, Moriguchi-City, Osaka, 570-8507, JapanTel + 81-6-6992-1001Fax + 81-6-6992-1066Email shimizto@takii.kmu.ac.jpBackground: Tocilizumab (TCZ) is humanized monoclonal antibody against the interleukin-6 (IL-6) and receptor that has prominent efficacy for the treatment of rheumatoid arthritis (RA). We conducted a retrospective observational study to determine how long TCZ controls RA.Patients and Methods: We retrospectively reviewed the medical records of RA patients treated with TCZ. The aim of this study was to evaluate the contribution of clinical parameters to disease control time (DCT) in RA patients.Results: Overall, 144 patients were enrolled in the study. The median age of patients was 66 years (range: 34– 85 years). In univariate analysis, DCT was significantly increased in patients who had never received previous biologic disease-modifying anti-rheumatic drugs treatment (P = 0.0064). We also analyzed the contribution of the base line value of C-reactive protein (CRP) to DCT. We divided the patients with RA into two groups according to a cutoff value of 1.000 mg/dl. The median control times were 77.5 months (95% confidence interval [CI]: 44.8–not reached to median) and 34.5 months (95% CI: 17.0– 79.3) for patients with high and low CRP value, respectively. In univariate analysis, DCT was significantly increased in patients with a high CRP value (P = 0.0283). Multivariate analysis clearly revealed that a high baseline CRP value was an independent favorable predictive factor for longer DCT (hazard ratio, 0.608, 95% CI: 0.378– 0.981, P = 0.0416).Conclusion: These data clearly demonstrate that the baseline value of CRP was closely associated with long time DCT in patients of RA treated with TCZ.Keywords: rheumatoid arthritis, tocilizumab, C-reactive protein, platelet large cell ratio, disease control time

Published
2021

3. Anti-atherosclerotic effects of sitagliptin in patients with type 2 diabetes mellitus

Author

Omoto S, Taniura T, Nishizawa T, Tamaki T, and Shouzu A,Nomura S

Subjects
Specialties of internal medicine, RC581-951
Abstract

Seitaro Omoto,1 Takehito Taniura,2 Tohru Nishizawa,3 Takeshi Tamaki,3 Akira Shouzu,4 Shosaku Nomura3 1Division of Internal Medicine, Korigaoka Yukeikai Hospital, 2Division of Internal Medicine, Daiwa Hospital, 3First Department of Internal Medicine, Kansai Medical University, 4Division of Internal Medicine, Saiseikai Izuo Hospital, Osaka, Japan Background: Advanced glycation end products, selectins, and adiponectin play important roles in the development of atherosclerosis in individuals with diabetes. Sitagliptin has been shown to reduce the concentration of glycated hemoglobin in diabetic patients. However, its effects on soluble receptor for advanced glycation end products (sRAGEs), selectins, and adiponectin in these patients are poorly understood. This study was conducted to assess the effects of sitagliptin on the circulating levels of sRAGEs, monocyte chemoattractant protein-1 (MCP-1), selectins, and adiponectin in patients with type 2 diabetes. Methods: Diabetic patients eligible for sitagliptin monotherapy or combination therapy (eg, sitagliptin plus a sulfonylurea) were administered sitagliptin (50 mg/day) for 6 months. Levels of soluble P-selectin (sP-selectin), soluble E-selectin (sE-selectin), soluble vascular cell adhesion molecule-1 (sVCAM-1), MCP-1, sRAGEs, and adiponectin were measured by ELISA at baseline and after 3 and 6 months of treatment. Results: At baseline, the levels of MCP-1, sP-selectin, sE-selectin, and sVCAM-1 were higher and the level of adiponectin was lower in diabetic patients than in nondiabetic patients. Sitagliptin therapy for 3 and 6 months significantly reduced plasma levels of sP-selectin, sE-selectin, sVCAM-1, and MCP-1 relative to baseline, while significantly increasing adiponectin levels. sRAGEs did not exhibit a statistical significance, although there was an increasing tendency. Furthermore, the reductions in sP-selectin, sE-selectin, sVCAM-1, and MCP-1 during sitagliptin therapy were significantly greater in responders, defined as patients with a significant increase in adiponectin levels, than in nonresponders. In contrast, responders showed a significant increase in the plasma concentration of sRAGEs. Conclusion: Sitagliptin shows an adiponectin-dependent anti-atherothrombotic effect, which may be beneficial for primary prevention of atherothrombosis, in patients with type 2 diabetes. Keywords: type 2 diabetes mellitus, sitagliptin, sRAGE, selectins, sVCAM-1, adiponectin

Published
2015

5. Usefulness of CT Image Quantitative Analysis for Predicting the Onset of Drug-Induced Lung Injury in Chemotherapy for Elderly Lung Cancer

Author

Shimizu, T., primary, Nakagawa, Y., additional, Asai, Y., additional, Nishizawa, T., additional, Iida, Y., additional, Nomoto, M., additional, Nakamoto, T., additional, Miyamoto, I., additional, Kusahana, R., additional, Nakayama, R., additional, Tanaka, R., additional, Ono, M., additional, Mizuno, Y., additional, Tsujino, I., additional, and Gon, Y., additional

Published
2024
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8. Rotational movement analysis based on Fourier-rectangular function transform for cylindrical plasma.

Author

Nishimura, D., Fujisawa, A., Yamasaki, K., Nagashima, Y., Moon, C., Nishizawa, T., Kobayashi, T.-K., Kobayashi, T., Shimizu, A., Tokuzawa, T., and Ido, T.

Subjects
CYLINDRICAL plasmas, STELLAR oscillations, PLASMA dynamics
Abstract

This article presents a method to estimate the rotational velocity of a cylindrical plasma from its two-dimensional images by an extended use of the Fourier-rectangular function transform, which was proposed to analyze the structure and dynamics of a cylindrical plasma [K. Yamasaki e t a l., J. Appl. Phys. 126 , 043304 (2019)]. The proposed method is applied to tomography images of plasmas produced in a linear cylindrical device and succeeds in obtaining the radial distribution of rotational velocity and its fluctuations, providing an interesting finding, that is, the existence of flow modulation associated with m = 1 mode fluctuations. [ABSTRACT FROM AUTHOR]

Published
2023
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10. Estimation of plasma parameter profiles and their derivatives from linear observations by using Gaussian processes

Author

Nishizawa, T, primary, Tokuda, S, additional, Kobayashi, T, additional, Tanaka, K, additional, Funaba, H, additional, Yamada, I, additional, Takemura, Y, additional, Tokuzawa, T, additional, Yasuhara, R, additional, Uehara, H, additional, Ida, K, additional, Takahashi, H, additional, Kawachi, Y, additional, Inagaki, S, additional, Kado, S, additional, Sasaki, M, additional, and Fujisawa, A, additional

Published
2023
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11. Bre1-nucleosome complex (Model II)

Author

Onishi, S., primary, Sato, K., additional, Hamada, K., additional, Nishizawa, T., additional, Nureki, O., additional, Ogata, K., additional, and Sengoku, T., additional

Published
2023
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15. Development of EarthCARE algorithms for the study of clouds, aerosol and radiation

Author

Okamoto, H., Sato, K., and Nishizawa, T.

Abstract

We describe the JAXA algorithms and products from the Earth Clouds Aerosol and Radiation Explorer (EarthCARE). EarthCARE is a joint mission by Japan Aerospace Exploration Agency (JAXA) and the European Space Agency (ESA) to understand clouds, aerosols and radiation. It will carry Doppler cloud profiling radar (CPR), atmospheric high spectral resolution lidar (ATLID), multi-le spectral imager (MSI) and broad band radiometer (BBR) JAXA EarthCARE algorithms have been extended from the algorithms for CloudSat, CALIPSO and MODIS to produce Kyushu (KU) products and JAXA EarthCARE A-train products. Doppler capability of CPR is expected to provide terminal velocity of cloud/precipitation particles and vertical air motion inside clouds. High spectral resolution lidar ATLID provides true backscattering coefficient, extinction coefficient and depolarization ratio. Theoretical studies have indicated that the two-dimensional diagram of lidar ratio and depolarization ratio is essential not only for aerosol components but for retrieving cloud particle shapes and orientations (Okamoto et al., 2019, 2020). Recently developed physical model (Sato et al., 2018) and vectorized physical model (Sato et al., 2019) can be used to take lidar multiple scattering into account for the interpretation of active sensor signals of optically thick clouds. Synergy of new observations with the theoretical improvements enables better estimation of radiative characteristics of cloud/precipitation/aerosol particles.Synergetic ground-based observation systems have been developed to evaluate the EarthCARE algorithms. It consists of Multi-Field-of-view Multiple Scattering Polarization Lidar, high spectral resolution lidar, direct and coherent Doppler lidars and high-sensitivity-cloud radar.&nbsp, The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

Published
2023
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20. THE EARTHCARE SATELLITE : The Next Step Forward in Global Measurements of Clouds, Aerosols, Precipitation, and Radiation

Author

Illingworth, A. J., Barker, H. W., Beljaars, A., Ceccaldi, M., Chepfer, H., Clerbaux, N., Cole, J., Delanoë, J., Domenech, C., Donovan, D. P., Fukuda, S., Hirakata, M., Hogan, R. J., Huenerbein, A., Kollias, P., Kubota, T., Nakajima, T., Nakajima, T. Y., Nishizawa, T., Ohno, Y., Okamoto, H., Oki, R., Sato, K., Satoh, M., Shephard, M. W., Velázquez-Blázquez, A., Wandinger, U., Wehr, T., and van Zadelhoff, G.-J.

Published
2015

26. PTH-bound human PTH1R in complex with Gs (class4)

Author

Kobayashi, K., primary, Kusakizako, T., additional, Miyauchi, H., additional, Tomita, A., additional, Kobayashi, K., additional, Shihoya, W., additional, Yamashita, K., additional, Nishizawa, T., additional, Kato, H.E., additional, and Nureki, O., additional

Published
2022
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27. PTHrP-bound human PTH1R in complex with Gs

Author

Kobayashi, K., primary, Kusakizako, T., additional, Miyauchi, H., additional, Tomita, A., additional, Kobayashi, K., additional, Shihoya, W., additional, Yamashita, K., additional, Nishizawa, T., additional, Kato, H.E., additional, and Nureki, O., additional

Published
2022
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29. Cryo-EM structure of Rhizobium etli MprF

Author

Nishimura, M., primary, Hirano, H., additional, Kobayashi, K., additional, Gill, C.P., additional, Phan, C.N.K., additional, Kise, Y., additional, Kusakizako, T., additional, Yamashita, K., additional, Ito, Y., additional, Roy, H., additional, Nishizawa, T., additional, and Nureki, O., additional

Published
2022
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30. human NTCP in complex with YN69083 Fab

Author

Park, J.H., primary, Iwamoto, M., additional, Yun, J.H., additional, Uchikubo-Kamo, T., additional, Son, D., additional, Jin, Z., additional, Yoshida, H., additional, Ohki, M., additional, Ishimoto, N., additional, Mizutani, K., additional, Oshima, M., additional, Muramatsu, M., additional, Wakita, T., additional, Shirouzu, M., additional, Liu, K., additional, Uemura, T., additional, Nomura, N., additional, Iwata, S., additional, Watashi, K., additional, Tame, J.R.H., additional, Nishizawa, T., additional, Lee, W., additional, and Park, S.Y., additional

Published
2022
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34. Cryo-EM structure of VCCN1 in detergent

Author

Hagino, T., primary, Kato, T., additional, Kasuya, G., additional, Kobayashi, K., additional, Kusakizako, T., additional, Yamashita, K., additional, Nishizawa, T., additional, and Nureki, O., additional

Published
2022
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37. Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X

Author

Sunn Pedersen, Thomas, primary, Abramovic, I., additional, Agostinetti, P., additional, Agredano Torres, M., additional, Äkäslompolo, S., additional, Alcuson Belloso, J., additional, Aleynikov, P., additional, Aleynikova, K., additional, Alhashimi, M., additional, Ali, A., additional, Allen, N., additional, Alonso, A., additional, Anda, G., additional, Andreeva, T., additional, Angioni, C., additional, Arkhipov, A., additional, Arnold, A., additional, Asad, W., additional, Ascasibar, E., additional, Aumeunier, M.-H., additional, Avramidis, K., additional, Aymerich, E., additional, Baek, S.-G., additional, Bähner, J., additional, Baillod, A., additional, Balden, M., additional, Baldzuhn, J., additional, Ballinger, S., additional, Banduch, M., additional, Bannmann, S., additional, Banon Navarro, A., additional, Bañón Navarro, A., additional, Barbui, T., additional, Beidler, C., additional, Belafdil, C., additional, Bencze, A., additional, Benndorf, A., additional, Beurskens, M., additional, Biedermann, C., additional, Biletskyi, O., additional, Blackwell, B., additional, Blatzheim, M., additional, Bluhm, T., additional, Böckenhoff, D., additional, Bongiovi, G., additional, Borchardt, M., additional, Borodin, D., additional, Boscary, J., additional, Bosch, H., additional, Bosmann, T., additional, Böswirth, B., additional, Böttger, L., additional, Bottino, A., additional, Bozhenkov, S., additional, Brakel, R., additional, Brandt, C., additional, Bräuer, T., additional, Braune, H., additional, Brezinsek, S., additional, Brunner, K., additional, Buller, S., additional, Burhenn, R., additional, Bussiahn, R., additional, Buttenschön, B., additional, Buzás, A., additional, Bykov, V., additional, Calvo, I., additional, Camacho Mata, K., additional, Caminal, I., additional, Cannas, B., additional, Cappa, A., additional, Carls, A., additional, Carovani, F., additional, Carr, M., additional, Carralero, D., additional, Carvalho, B., additional, Casas, J., additional, Castano-Bardawil, D., additional, Castejon, F., additional, Chaudhary, N., additional, Chelis, I., additional, Chomiczewska, A., additional, Coenen, J.W., additional, Cole, M., additional, Cordella, F., additional, Corre, Y., additional, Crombe, K., additional, Cseh, G., additional, Csillag, B., additional, Damm, H., additional, Day, C., additional, de Baar, M., additional, De la Cal, E., additional, Degenkolbe, S., additional, Demby, A., additional, Denk, S., additional, Dhard, C., additional, Di Siena, A., additional, Dinklage, A., additional, Dittmar, T., additional, Dreval, M., additional, Drevlak, M., additional, Drewelow, P., additional, Drews, P., additional, Dunai, D., additional, Edlund, E., additional, Effenberg, F., additional, Ehrke, G., additional, Endler, M., additional, Ennis, D.A., additional, Escoto, F.J., additional, Estrada, T., additional, Fable, E., additional, Fahrenkamp, N., additional, Fanni, A., additional, Faustin, J., additional, Fellinger, J., additional, Feng, Y., additional, Figacz, W., additional, Flom, E., additional, Ford, O., additional, Fornal, T., additional, Frerichs, H., additional, Freundt, S., additional, Fuchert, G., additional, Fukuyama, M., additional, Füllenbach, F., additional, Gantenbein, G., additional, Gao, Y., additional, Garcia, K., additional, García Regaña, J.M., additional, García-Cortés, I., additional, Gaspar, J., additional, Gates, D.A., additional, Geiger, J., additional, Geiger, B., additional, Giudicotti, L., additional, González, A., additional, Goriaev, A., additional, Gradic, D., additional, Grahl, M., additional, Graves, J.P., additional, Green, J., additional, Grelier, E., additional, Greuner, H., additional, Groß, S., additional, Grote, H., additional, Groth, M., additional, Gruca, M., additional, Grulke, O., additional, Grün, M., additional, Guerrero Arnaiz, J., additional, Günter, S., additional, Haak, V., additional, Haas, M., additional, Hacker, P., additional, Hakola, A., additional, Hallenbert, A., additional, Hammond, K., additional, Han, X., additional, Hansen, S.K., additional, Harris, J.H., additional, Hartfuß, H., additional, Hartmann, D., additional, Hathiramani, D., additional, Hatzky, R., additional, Hawke, J., additional, Hegedus, S., additional, Hein, B., additional, Heinemann, B., additional, Helander, P., additional, Henneberg, S., additional, Hergenhahn, U., additional, Hidalgo, C., additional, Hindenlang, F., additional, Hirsch, M., additional, Höfel, U., additional, Hollfeld, K.P., additional, Holtz, A., additional, Hopf, D., additional, Höschen, D., additional, Houry, M., additional, Howard, J., additional, Huang, X., additional, Hubeny, M., additional, Hudson, S., additional, Ida, K., additional, Igitkhanov, Y., additional, Igochine, V., additional, Illy, S., additional, Ionita-Schrittwieser, C., additional, Isobe, M., additional, Jabłczyńska, M., additional, Jablonski, S., additional, Jagielski, B., additional, Jakubowski, M., additional, Jansen van Vuuren, A., additional, Jelonnek, J., additional, Jenko, F., additional, Jensen, T., additional, Jenzsch, H., additional, Junghanns, P., additional, Kaczmarczyk, J., additional, Kallmeyer, J., additional, Kamionka, U., additional, Kandler, M., additional, Kasilov, S., additional, Kazakov, Y., additional, Kennedy, D., additional, Kharwandikar, A., additional, Khokhlov, M., additional, Kiefer, C., additional, Killer, C., additional, Kirschner, A., additional, Kleiber, R., additional, Klinger, T., additional, Klose, S., additional, Knauer, J., additional, Knieps, A., additional, Köchl, F., additional, Kocsis, G., additional, Kolesnichenko, Ya.I., additional, Könies, A., additional, König, R., additional, Kontula, J., additional, Kornejew, P., additional, Koschinsky, J., additional, Kozulia, M.M., additional, Krämer-Flecken, A., additional, Krampitz, R., additional, Krause, M., additional, Krawczyk, N., additional, Kremeyer, T., additional, Krier, L., additional, Kriete, D.M., additional, Krychowiak, M., additional, Ksiazek, I., additional, Kubkowska, M., additional, Kuczynski, M., additional, Kühner, G., additional, Kumar, A., additional, Kurki-Suonio, T., additional, Kwak, S., additional, Landreman, M., additional, Lang, P.T., additional, Langenberg, A., additional, Laqua, H.P., additional, Laqua, H., additional, Laube, R., additional, Lazerson, S., additional, Lewerentz, M., additional, Li, C., additional, Liang, Y., additional, Linsmeier, Ch., additional, Lion, J., additional, Litnovsky, A., additional, Liu, S., additional, Lobsien, J., additional, Loizu, J., additional, Lore, J., additional, Lorenz, A., additional, Losada, U., additional, Louche, F., additional, Lunsford, R., additional, Lutsenko, V., additional, Machielsen, M., additional, Mackel, F., additional, Maisano-Brown, J., additional, Maj, O., additional, Makowski, D., additional, Manduchi, G., additional, Maragkoudakis, E., additional, Marchuk, O., additional, Marsen, S., additional, Martines, E., additional, Martinez-Fernandez, J., additional, Marushchenko, M., additional, Masuzaki, S., additional, Maurer, D., additional, Mayer, M., additional, McCarthy, K.J., additional, Mccormack, O., additional, McNeely, P., additional, Meister, H., additional, Mendelevitch, B., additional, Mendes, S., additional, Merlo, A., additional, Messian, A., additional, Mielczarek, A., additional, Mishchenko, O., additional, Missal, B., additional, Mitteau, R., additional, Moiseenko, V.E., additional, Mollen, A., additional, Moncada, V., additional, Mönnich, T., additional, Morisaki, T., additional, Moseev, D., additional, Motojima, G., additional, Mulas, S., additional, Mulsow, M., additional, Nagel, M., additional, Naujoks, D., additional, Naulin, V., additional, Neelis, T., additional, Neilson, H., additional, Neu, R., additional, Neubauer, O., additional, Neuner, U., additional, Nicolai, D., additional, Nielsen, S.K., additional, Niemann, H., additional, Nishiza, T., additional, Nishizawa, T., additional, Nührenberg, C., additional, Ochoukov, R., additional, Oelmann, J., additional, Offermanns, G., additional, Ogawa, K., additional, Okamura, S., additional, Ölmanns, J., additional, Ongena, J., additional, Oosterbeek, J., additional, Otte, M., additional, Pablant, N., additional, Panadero Alvarez, N., additional, Pandey, A., additional, Pasch, E., additional, Pavlichenko, R., additional, Pavone, A., additional, Pawelec, E., additional, Pechstein, G., additional, Pelka, G., additional, Perseo, V., additional, Peterson, B., additional, Pilopp, D., additional, Pingel, S., additional, Pisano, F., additional, Plöckl, B., additional, Plunk, G., additional, Pölöskei, P., additional, Pompe, B., additional, Popov, A., additional, Porkolab, M., additional, Proll, J., additional, Pueschel, M.J., additional, Puiatti, M.-E., additional, Puig Sitjes, A., additional, Purps, F., additional, Rahbarnia, K., additional, Rasiński, M., additional, Rasmussen, J., additional, Reiman, A., additional, Reimold, F., additional, Reisner, M., additional, Reiter, D., additional, Richou, M., additional, Riedl, R., additional, Riemann, J., additional, Riße, K., additional, Roberg-Clark, G., additional, Rohde, V., additional, Romazanov, J., additional, Rondeshagen, D., additional, Rong, P., additional, Rudischhauser, L., additional, Rummel, T., additional, Rummel, K., additional, Runov, A., additional, Rust, N., additional, Ryc, L., additional, Salembier, P., additional, Salewski, M., additional, Sanchez, E., additional, Satake, S., additional, Satheeswaran, G., additional, Schacht, J., additional, Scharff, E., additional, Schauer, F., additional, Schilling, J., additional, Schlisio, G., additional, Schmid, K., additional, Schmitt, J., additional, Schmitz, O., additional, Schneider, W., additional, Schneider, M., additional, Schneider, P., additional, Schrittwieser, R., additional, Schröder, T., additional, Schröder, M., additional, Schroeder, R., additional, Schweer, B., additional, Schwörer, D., additional, Scott, E., additional, Shanahan, B., additional, Sias, G., additional, Sichta, P., additional, Singer, M., additional, Sinha, P., additional, Sipliä, S., additional, Slaby, C., additional, Sleczka, M., additional, Smith, H., additional, Smoniewski, J., additional, Sonnendrücker, E., additional, Spolaore, M., additional, Spring, A., additional, Stadler, R., additional, Stańczak, D., additional, Stange, T., additional, Stepanov, I., additional, Stephey, L., additional, Stober, J., additional, Stroth, U., additional, Strumberger, E., additional, Suzuki, C., additional, Suzuki, Y., additional, Svensson, J., additional, Szabolics, T., additional, Szepesi, T., additional, Szücs, M., additional, Tabarés, F.L., additional, Tamura, N., additional, Tancetti, A., additional, Tantos, C., additional, Terry, J., additional, Thienpondt, H., additional, Thomsen, H., additional, Thumm, M., additional, Travere, J.M., additional, Traverso, P., additional, Tretter, J., additional, Trier, E., additional, Trimino Mora, H., additional, Tsujimura, T., additional, Turkin, Y., additional, Tykhyi, A., additional, Unterberg, B., additional, van Eeten, P., additional, van Milligen, B.Ph., additional, van Schoor, M., additional, Vano, L., additional, Varoutis, S., additional, Vecsei, M., additional, Vela, L., additional, Velasco, J.L., additional, Vervier, M., additional, Vianello, N., additional, Viebke, H., additional, Vilbrandt, R., additional, Vogel, G., additional, Vogt, N., additional, Volkhausen, C., additional, von Stechow, A., additional, Wagner, F., additional, Wang, E., additional, Wang, H., additional, Warmer, F., additional, Wauters, T., additional, Wegener, L., additional, Wegner, T., additional, Weir, G., additional, Wenzel, U., additional, White, A., additional, Wilde, F., additional, Wilms, F., additional, Windisch, T., additional, Winkler, M., additional, Winter, A., additional, Winters, V., additional, Wolf, R., additional, Wright, A.M., additional, Wurden, G.A., additional, Xanthopoulos, P., additional, Xu, S., additional, Yamada, H., additional, Yamaguchi, H., additional, Yokoyama, M., additional, Yoshinuma, M., additional, Yu, Q., additional, Zamanov, M., additional, Zanini, M., additional, Zarnstorff, M., additional, Zhang, D., additional, Zhou, S., additional, Zhu, J., additional, Zhu, C., additional, Zilker, M., additional, Zocco, A., additional, Zohm, H., additional, Zoletnik, S., additional, and Zsuga, L., additional

Published
2022
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38. Effects of salinity stress induced by hot spring water on tomato growth, yield and fruit quality under hydroponic cultivation in Japan.

Author

Musabyisoni, A., Nishizawa, T., Mutimawurugo, M. C., and Niyokuri, A. N.

Subjects
TOMATO yields, FRUIT quality, EFFECT of stress on plants, ORGANIC acids
Abstract

The objective of this research was to test hot spring water as a source of salt to improve tomato quality under the hydroponic system. This research was conducted at Yamagata University, in Japan from February to July 2017. Salt stress was induced using salts of hot spring wastewater collected from Yupoka Onsen (Tsuruoka, Japan). The treatments were EC 2, 4, 8 12, and 16 mS/cm which were arranged in a Randomized Complete Block Design (RCBD) with five replications. Tomato plants were grown at EC 2 until flowering and then subjected to different EC concentrations until harvesting. The data were collected on plant growth parameters and fruit quality. Fruits were harvested at the red stage until the 5th truss. The results showed that fruits' Soluble Solids Content, organic acid, Nitrate contents and Sugar: Acid ratio increased significantly at EC 16 mS/cm and in the upper trusses compared to EC 2 and in the lower trusses. In contrast, fruit weight significantly decreased at EC 16 mS/cm and in upper trusses. Leaf thickness, size and SPAD, and specific leaf weight significantly declined at EC 16 mS/cm and upper leaves compared to EC 2 and in lower leaves. Plant height started to decline significantly after three weeks of treatment at EC 16 compared to EC 2. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Structure of the Dicer-2-R2D2 heterodimer

Author

Yamaguchi, S., primary, Nishizawa, T., additional, Kusakizako, T., additional, Yamashita, K., additional, Tomita, A., additional, Hirano, H., additional, Nishimasu, H., additional, and Nureki, O., additional

Published
2022
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41. Progress from ASDEX Upgrade experiments in preparing the physics basis of ITER operation and DEMO scenario development

Author

Stroth, U., primary, Aguiam, D., additional, Alessi, E., additional, Angioni, C., additional, Arden, N., additional, Parra, R. Arredondo, additional, Artigues, V., additional, Asunta, O., additional, Balden, M., additional, Bandaru, V., additional, Banon-Navarro, A., additional, Behler, K., additional, Bergmann, A., additional, Bergmann, M., additional, Bernardo, J., additional, Bernert, M., additional, Biancalani, A., additional, Bielajew, R., additional, Bilato, R., additional, Birkenmeier, G., additional, Blanken, T., additional, Bobkov, V., additional, Bock, A., additional, Body, T., additional, Bolzonella, T., additional, Bonanomi, N., additional, Bortolon, A., additional, Böswirth, B., additional, Bottereau, C., additional, Bottino, A., additional, van den Brand, H., additional, Brenzke, M., additional, Brezinsek, S., additional, Brida, D., additional, Brochard, F., additional, Bruhn, C., additional, Buchanan, J., additional, Buhler, A., additional, Burckhart, A., additional, Camenen, Y., additional, Cannas, B., additional, Megias, P. Cano, additional, Carlton, D., additional, Carr, M., additional, Carvalho, P., additional, Castaldo, C., additional, Cavedon, M., additional, Cazzaniga, C., additional, Challis, C., additional, Chankin, A., additional, Cianfarani, C., additional, Clairet, F., additional, Coda, S., additional, Coelho, R., additional, Coenen, J.W., additional, Colas, L., additional, Conway, G., additional, Costea, S., additional, Coster, D., additional, Cote, T., additional, Creely, A.J., additional, Croci, G., additional, Zabala, D.J. Cruz, additional, Cseh, G., additional, Czarnecka, A., additional, Cziegler, I., additional, D’Arcangelo, O., additional, Molin, A. Dal, additional, David, P., additional, Day, C., additional, de Baar, M., additional, de Marné, P., additional, Delogu, R., additional, Denk, S., additional, Denner, P., additional, Di Siena, A., additional, Palacios Durán, J.J. Dominguez, additional, Dunai, D., additional, Drenik, A., additional, Dreval, M., additional, Drube, R., additional, Dunne, M., additional, Duval, B.P., additional, Dux, R., additional, Eich, T., additional, Elgeti, S., additional, Encheva, A., additional, Engelhardt, K., additional, Erdös, B., additional, Erofeev, I., additional, Esposito, B., additional, Fable, E., additional, Faitsch, M., additional, Fantz, U., additional, Farnik, M., additional, Faugel, H., additional, Felici, F., additional, Ficker, O., additional, Fietz, S., additional, Figueredo, A., additional, Fischer, R., additional, Ford, O., additional, Frassinetti, L., additional, Fröschle, M., additional, Fuchert, G., additional, Fuchs, J.C., additional, Fünfgelder, H., additional, Futatani, S., additional, Galazka, K., additional, Galdon-Quiroga, J., additional, Escolà, D. Gallart, additional, Gallo, A., additional, Gao, Y., additional, Garavaglia, S., additional, Muñoz, M. Garcia, additional, Geiger, B., additional, Giannone, L., additional, Gibson, S., additional, Gil, L., additional, Giovannozzi, E., additional, Glöggler, S., additional, Gobbin, M., additional, Martin, J. Gonzalez, additional, Goodman, T., additional, Gorini, G., additional, Görler, T., additional, Gradic, D., additional, Granucci, G., additional, Gräter, A., additional, Greuner, H., additional, Griener, M., additional, Groth, M., additional, Gude, A., additional, Guimarais, L., additional, Günter, S., additional, Haas, G., additional, Hakola, A.H., additional, Ham, C., additional, Happel, T., additional, den Harder, N., additional, Harrer, G., additional, Harrison, J., additional, Hauer, V., additional, Hayward-Schneider, T., additional, Heinemann, B., additional, Hellsten, T., additional, Henderson, S., additional, Hennequin, P., additional, Herrmann, A., additional, Heyn, E., additional, Hitzler, F., additional, Hobirk, J., additional, Höfler, K., additional, Holm, J.H., additional, Hölzl, M., additional, Hopf, C., additional, Horvath, L., additional, Höschen, T., additional, Houben, A., additional, Hubbard, A., additional, Huber, A., additional, Hunger, K., additional, Igochine, V., additional, Iliasova, M., additional, Ilkei, T., additional, Björk, K. Insulander, additional, Ionita-Schrittwieser, C., additional, Ivanova-Stanik, I., additional, Jacob, W., additional, Jaksic, N., additional, Janky, F., additional, Jansen van Vuuren, A., additional, Jardin, A., additional, Jaulmes, F., additional, Jenko, F., additional, Jensen, T., additional, Joffrin, E., additional, Kallenbach, A., additional, Kálvin, S., additional, Kantor, M., additional, Kappatou, A., additional, Kardaun, O., additional, Karhunen, J., additional, Käsemann, C.-P., additional, Kasilov, S., additional, Kendl, A., additional, Kernbichler, W., additional, Khilkevitch, E., additional, Kirk, A., additional, Hansen, S. Kjer, additional, Klevarova, V., additional, Kocsis, G., additional, Koleva, M., additional, Komm, M., additional, Kong, M., additional, Krämer-Flecken, A., additional, Krieger, K., additional, Krivska, A., additional, Kudlacek, O., additional, Kurki-Suonio, T., additional, Kurzan, B., additional, Labit, B., additional, Lackner, K., additional, Laggner, F., additional, Lahtinen, A., additional, Lang, P.T., additional, Lauber, P., additional, Leuthold, N., additional, Li, L., additional, Likonen, J., additional, Linder, O., additional, Lipschultz, B., additional, Liu, Y., additional, Lohs, A., additional, Lu, Z., additional, Luda di Cortemiglia, T., additional, Luhmann, N.C., additional, Lunt, T., additional, Lyssoivan, A., additional, Maceina, T., additional, Madsen, J., additional, Magnanimo, A., additional, Maier, H., additional, Mailloux, J., additional, Maingi, R., additional, Maj, O., additional, Maljaars, E., additional, Manas, P., additional, Mancini, A., additional, Manhard, A., additional, Mantica, P., additional, Mantsinen, M., additional, Manz, P., additional, Maraschek, M., additional, Marchetto, C., additional, Marrelli, L., additional, Martin, P., additional, Martitsch, A., additional, Matos, F., additional, Mayer, M., additional, Mayoral, M.-L., additional, Mazon, D., additional, McCarthy, P.J., additional, McDermott, R., additional, Merkel, R., additional, Merle, A., additional, Meshcheriakov, D., additional, Meyer, H., additional, Milanesio, D., additional, Cabrera, P. Molina, additional, Monaco, F., additional, Muraca, M., additional, Nabais, F., additional, Naulin, V., additional, Nazikian, R., additional, Nem, R.D., additional, Nemes-Czopf, A., additional, Neu, G., additional, Neu, R., additional, Nielsen, A.H., additional, Nielsen, S.K., additional, Nishizawa, T., additional, Nocente, M., additional, Noterdaeme, J.-M., additional, Novikau, I., additional, Nowak, S., additional, Oberkofler, M., additional, Ochoukov, R., additional, Olsen, J., additional, Orain, F., additional, Palermo, F., additional, Pan, O., additional, Papp, G., additional, Perez, I. Paradela, additional, Pau, A., additional, Pautasso, G., additional, Paz-Soldan, C., additional, Petersson, P., additional, Piovesan, P., additional, Piron, C., additional, Plank, U., additional, Plaum, B., additional, Plöck, B., additional, Plyusnin, V., additional, Pokol, G., additional, Poli, E., additional, Porte, L., additional, Pütterich, T., additional, Ramisch, M., additional, Rasmussen, J., additional, Ratta, G., additional, Ratynskaia, S., additional, Raupp, G., additional, Réfy, D., additional, Reich, M., additional, Reimold, F., additional, Reiser, D., additional, Reisner, M., additional, Reiter, D., additional, Ribeiro, T., additional, Riedl, R., additional, Riesch, J., additional, Rittich, D., additional, Rodriguez, J.F. Rivero, additional, Rocchi, G., additional, Rodriguez-Fernandez, P., additional, Rodriguez-Ramos, M., additional, Rohde, V., additional, Ronchi, G., additional, Ross, A., additional, Rott, M., additional, Rubel, M., additional, Ryan, D.A., additional, Ryter, F., additional, Saarelma, S., additional, Salewski, M., additional, Salmi, A., additional, Samoylov, O., additional, Sanchez, L. Sanchis, additional, Santos, J., additional, Sauter, O., additional, Schall, G., additional, Schlüter, K., additional, Schmid, K., additional, Schmitz, O., additional, Schneider, P.A., additional, Schrittwieser, R., additional, Schubert, M., additional, Schuster, C., additional, Schwarz-Selinger, T., additional, Schweinzer, J., additional, Seliunin, E., additional, Shabbir, A., additional, Shalpegin, A., additional, Sharapov, S., additional, Sheikh, U., additional, Shevelev, A., additional, Sias, G., additional, Siccinio, M., additional, Sieglin, B., additional, Sigalov, A., additional, Silva, A., additional, Silva, C., additional, Silvagni, D., additional, Simpson, J., additional, Sipilä, S., additional, Smigelskis, E., additional, Snicker, A., additional, Solano, E., additional, Sommariva, C., additional, Sozzi, C., additional, Spizzo, G., additional, Spolaore, M., additional, Stegmeir, A., additional, Stejner, M., additional, Stober, J., additional, Strumberge, E., additional, Lopez, G. Suarez, additional, Sun, H.-J., additional, Suttrop, W., additional, Sytova, E., additional, Szepesi, T., additional, Tál, B., additional, Tala, T., additional, Tardini, G., additional, Tardocchi, M., additional, Terranova, D., additional, Teschke, M., additional, Thorén, E., additional, Tierens, W., additional, Told, D., additional, Treutterer, W., additional, Trevisan, G., additional, Trier, E., additional, Tripský, M., additional, Usoltceva, M., additional, Valisa, M., additional, Valovic, M., additional, van Zeeland, M., additional, Vannini, F., additional, Vanovac, B., additional, Varela, P., additional, Varoutis, S., additional, Vianello, N., additional, Vicente, J., additional, Verdoolaege, G., additional, Vierle, T., additional, Viezzer, E., additional, Voitsekhovitch, I., additional, von Toussaint, U., additional, Wagner, D., additional, Wang, X., additional, Weiland, M., additional, White, A.E., additional, Willensdorfer, M., additional, Wiringer, B., additional, Wischmeier, M., additional, Wolf, R., additional, Wolfrum, E., additional, Yang, Q., additional, Yu, Q., additional, Zagórski, R., additional, Zammuto, I., additional, Zehetbauer, T., additional, Zhang, W., additional, Zholobenko, W., additional, Zilker, M., additional, Zito, A., additional, Zohm, H., additional, Zoletnik, S., additional, and EUROfusion MST1 Team, the, additional

Published
2022
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42. Determination of the background neutral density from passive Balmer alpha CX emission at the ASDEX Upgrade tokamak

Author

Van Vuuren, A. J., Bogar, K., Cruz Zabala, Diego José, Cavedon, M., Cano Megías, Pilar, Kappatou, A., Dux, R., Schneider, P. A., Viezzer, Eleonora, Nishizawa, T., García Muñoz, Manuel, ASDEX Upgrade Team, Max Planck Institute for Plasma Physics, Max Planck Society, Van Vuuren, A, Bogar, K, Cruz-Zabala, D, Cavedon, M, Cano-Megias, P, Kappatou, A, Dux, R, Schneider, P, Viezzer, E, Nishizawa, T, Garcia-Munoz, M, Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear, Universidad de Sevilla. Departamento de Ingeniería Energética, and EUROfusion Consortium

Subjects
Plasma
Abstract

EUROfusion Consortium 633053

Published
2021

44. Sugar Content Detection in Watermelon

Author

Miki, T., Saito, K., Hayashi, S., Kajikawa, H., Shimada, M., Ogawa, R., Kawate, K., Nishizawa, T., Ikegaya, D., Kimura, N., Takabatake, K., Sugiura, N., Suzuki, M., Hayakawa, Hisao, editor, and Enomoto, Youichi, editor

Published
1996
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50. Characterizing the flow and turbulence structure near the last closed flux surface in L-mode plasmas of ASDEX Upgrade

Author

Nishizawa, T., Manz, P., Grenfell, G., Griener, M., Wendler, D., Brida, D., Kriete, D., Dux, R., Kobayashi, T., Sasaki, M., and ASDEX Upgrade Team, Max Planck Institute for Plasma Physics, Max Planck Society

Subjects
Condensed Matter Physics
Abstract

Since high density operation is advantageous for building an efficient fusion reactor, understanding the density limit in tokamaks has been seen as one of the most important issues. This paper reports a series of measurements around the last-closed flux surface (LCFS) in L-mode plasmas by using a thermal helium beam diagnostic. Fluctuation analysis has been employed to characterize the poloidal flow and the turbulence structure. A reversal of the poloidal flow in the scrape-off layer and concomitant cooling of the outer divertor plasma are observed as the density is raised. While, in the confined region, the change in the density barely affects the poloidal flow, a higher density shifts the fluctuation power spectral densities toward lower frequencies and wave numbers. The eddy tilting of this region is consistent with what is expected from the magnetic shear effect. A radially coherent low frequency mode appears in the case of the highest density investigated in this study ([Formula: see text] = 0.51), and higher frequencies near the LCFS are modulated by this mode.

Published
2022

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