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587 results on '"Nishiyama, Tsutomu"'

1. KL‐6 Mucin as Serum Tumor Marker of Metastatic Renal Cancer: A Case Report.

Author

Ishida, Kyohei, Hasegawa, Go, Takada, Toshinori, Ogose, Akira, Kawaguchi, Gen, Ikeda, Yohei, Nishiyama, Hiroki, Hara, Noboru, Nishiyama, Tsutomu, and Koga, Fumitaka

Subjects
RENAL cancer, TUMOR markers, BIOMARKERS, KIDNEY failure, METASTASIS
Abstract

We encountered a case of metastatic renal cell carcinoma in which the serum level of KL‐6, a therapeutic marker, was exceptionally high and fluctuated with the progression of treatment. A 74‐year‐old man was diagnosed with right renal cystic cancer and multiple metastases in October 2022. The KL‐6 level was 27490 U/mL. He started treatment with lenvatinib and pembrolizumab. KL‐6 decreased to 3885 U/mg in February 2023. The patient's proteinuria worsened, leading to the discontinuation of lenvatinib. KL‐6 increased to 25950 U/mL in April. He discontinued pembrolizumab and started taking cabozantinib. In September, drug‐induced bilateral inflammatory pneumonitis developed. He discontinued cabozantinb and began taking axitinib. KL‐6 decreased; however, he suffered from severe diarrhea and subsequent renal insufficiency. He discontinued axitinib in November. KL‐6 increased to 29640 U/mL in December. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Bladder Cancer Invading the Prostate and Penis and Multiple Bone Metastases Showing Significant Improvement after a Short‐Term Pembrolizumab Therapy following Radiation and Gemcitabine and Cisplatin Therapy Leading to a Pathologically Complete Remission

Author

Ishida, Kyohei, Ogose, Akira, Kawaguchi, Gen, Hasegawa, Go, Ikeda, Yohei, Hara, Noboru, Nishiyama, Tsutomu, and Sheikh, Mehraj

Subjects
FEMORAL neck fractures, PROSTATE cancer, BONE metastasis, SPONTANEOUS fractures, PELVIC bones, HIP fractures
Abstract

A 65‐year‐old man was diagnosed with bladder cancer invading the prostate and penis and multiple bone metastases. He underwent palliative radiation (30 Gy/10 fr) through vertebral bones (Th3 and Th12‐L5) and pelvic bones for pain control. The patient received pembrolizumab therapy after three courses of gemcitabine and cisplatin therapy. CT four weeks after starting pembrolizumab therapy showed that both the primary and metastatic lesions had notably reduced in size, and no new lesion was detected. He subsequently fell, resulting in a femoral neck pathological fracture, and underwent hemiarthroplasty. Pathological examination of the pathological fracture site revealed no residual tumor tissue. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Significance of PSA Screening in Niigata, Japan: Survey of Actual Status of New Cases of Prostate Cancer

Author

Saito, Toshihiro, primary, Komatsubara, Shuichi, additional, Hara, Noboru, additional, Nishiyama, Tsutomu, additional, Katagiri, Akiyoshi, additional, Ishizaki, Fumio, additional, Hatano, Akihiko, additional, Komeyama, Takeshi, additional, Hanyu, Shugo, additional, Terunuma, Masahiro, additional, Imai, Tomoyuki, additional, Go, Hideto, additional, Iida, Hiroaki, additional, Kurumada, Shigenori, additional, Yamaguchi, Shunsuke, additional, Takeda, Keisuke, additional, Ando, Takashi, additional, Hoshii, Tatsuhiko, additional, Kasahara, Takashi, additional, and Tomita, Yoshihiko, additional

Published
2021
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33. Clear Cell Adenocarcinoma of the Ureter Similar to Clear Cell Renal Cell Carcinoma Histology

Author

Watanabe, Kazuhiro, Hasegawa, Go, Ikeda, Yohei, Hara, Noboru, and Nishiyama, Tsutomu

Subjects
Article Subject
Abstract

A 70-year-old woman was referred to our hospital with gross hematuria and diagnosed with right invasive ureteral cancer and bladder urothelial carcinoma in situ. Intravesical BCG therapy and neoadjuvant chemotherapy with carboplatin and gemcitabine were performed at the same time. Subsequently, laparoscopic right nephroureterectomy was performed. Urothelial carcinoma in situ persisted; however, most of the tumor was clear cell carcinoma. The clear cell carcinoma lesion had clear cytoplasm with round nuclei and visible nucleoli in an insular arrangement as is the case with clear cell renal cell carcinoma. No transitional lesion between clear cell adenocarcinoma and urothelial carcinoma was presented. The clear cell carcinoma lesion was GATA3 negative and HNF4α positive; however, the urothelial cancer lesion was GATA3 positive and HNF4α negative. Clear cell carcinoma was diagnosed as clear cell adenocarcinoma similar to clear cell renal cell carcinoma histology.

Published
2021
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35. A comparative study of high-dose-rate brachytherapy boost combined with external beam radiation therapy versus external beam radiation therapy alone for high-risk prostate cancer

Author

Oshikane, Tomoya, primary, Kaidu, Motoki, additional, Abe, Eisuke, additional, Ohta, Atsushi, additional, Saito, Hirotake, additional, Nakano, Toshimichi, additional, Honda, Moe, additional, Tanabe, Satoshi, additional, Utsunomiya, Satoru, additional, Sasamoto, Ryuta, additional, Ishizaki, Fumio, additional, Kasahara, Takashi, additional, Nishiyama, Tsutomu, additional, Tomita, Yoshihiko, additional, Aoyama, Hidefumi, additional, and Ishikawa, Hiroyuki, additional

Published
2021
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36. SUPP – Supplemental material for Granulocytic/myeloid sarcoma with trisomy 21 presented as an epididymal tumor: A case report and review of the literature

Author

Murata, Masaki, Inui, Kohei, Oki Nagano, Hasegawa, Go, Ikeda, Yohei, Seki, Yoshinobu, Nakagawa, Yuki, Moto Hasegawa, Hara, Noboru, and Nishiyama, Tsutomu

Subjects
FOS: Veterinary sciences, 111199 Nutrition and Dietetics not elsewhere classified, Cardiology, 170199 Psychology not elsewhere classified, 111799 Public Health and Health Services not elsewhere classified, 110604 Sports Medicine, FOS: Health sciences, 110306 Endocrinology, 110308 Geriatrics and Gerontology, 111099 Nursing not elsewhere classified, 111708 Health and Community Services, 160807 Sociological Methodology and Research Methods, 111702 Aged Health Care, 111403 Paediatrics, 110904 Neurology and Neuromuscular Diseases, 110203 Respiratory Diseases, 110315 Otorhinolaryngology, 70706 Veterinary Medicine, FOS: Clinical medicine, 110319 Psychiatry (incl. Psychotherapy), FOS: Sociology, FOS: Psychology, 110599 Dentistry not elsewhere classified, 110323 Surgery, 110305 Emergency Medicine, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified, 110314 Orthopaedics
Abstract

Supplemental material, SUPP for Granulocytic/myeloid sarcoma with trisomy 21 presented as an epididymal tumor: A case report and review of the literature by Masaki Murata, Kohei Inui, Oki Nagano, Go Hasegawa, Yohei Ikeda, Yoshinobu Seki, Yuki Nakagawa, Moto Hasegawa, Noboru Hara and Tsutomu Nishiyama in SAGE Open Medical Case Reports

Published
2020
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44. High‐dose‐rate brachytherapy and hypofractionated external beam radiotherapy combined with long‐term androgen deprivation therapy for very high‐risk prostate cancer

Author

Kasahara, Takashi, primary, Ishizaki, Fumio, additional, Kazama, Akira, additional, Yuki, Eri, additional, Yamana, Kazutoshi, additional, Maruyama, Ryo, additional, Oshikane, Tomoya, additional, Kaidu, Motoki, additional, Aoyama, Hidefumi, additional, Bilim, Vladimir, additional, Nishiyama, Tsutomu, additional, and Tomita, Yoshihiko, additional

Published
2020
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