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181 results on '"Nishimura, Yoji"'

4. Data from Three DNA Methylation Epigenotypes in Human Colorectal Cancer

Author

Yagi, Koichi, primary, Akagi, Kiwamu, primary, Hayashi, Hiroshi, primary, Nagae, Genta, primary, Tsuji, Shingo, primary, Isagawa, Takayuki, primary, Midorikawa, Yutaka, primary, Nishimura, Yoji, primary, Sakamoto, Hirohiko, primary, Seto, Yasuyuki, primary, Aburatani, Hiroyuki, primary, and Kaneda, Atsushi, primary

Published
2023
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15. Local control of sphincter‐preserving procedures and abdominoperineal resection for locally advanced low rectal cancer: Propensity score matched analysis

Author

Okamura, Ryosuke, Hida, Koya, Yamaguchi, Tomohiro, Akagi, Tomonori, Konishi, Tsuyoshi, Yamamoto, Michio, Ota, Mitsuyoshi, Matoba, Shuichiro, Bando, Hiroyuki, Goto, Saori, Sakai, Yoshiharu, Watanabe, Masahiko, Watanabe, Kazuteru, Otsuka, Koki, Takemasa, Ichiro, Tanaka, Keitaro, Ikeda, Masataka, Matsuda, Chu, Fukuda, Meiki, Hasegawa, Junichi, Akamoto, Shintaro, Shiozawa, Manabu, Tsuruta, Atsushi, Akiyoshi, Takashi, Kato, Takeshi, Tsukamoto, Shunsuke, Ito, Masaaki, Naito, Masaki, Kanazawa, Akiyoshi, Takahashi, Takao, Ueki, Takashi, Hayashi, Yuri, Morita, Satoshi, Yamaguchi, Takashi, Nakanishi, Masayoshi, Hasegawa, Hirotoshi, Okamoto, Ken, Teraishi, Fuminori, Sumi, Yasuo, Tashiro, Jo, Yatsuoka, Toshimasa, Nishimura, Yoji, Okita, Kenji, Kobatake, Takaya, Horie, Hisanaga, Miyakura, Yasuyuki, Ro, Hisashi, Nagakari, Kunihiko, Hidaka, Eiji, Umemoto, Takehiro, Nishigori, Hideaki, Murata, Kohei, Wakayama, Fuminori, Makizumi, Ryoji, Fujii, Shoichi, Sunami, Eiji, Kobayashi, Hirotoshi, Nakagawa, Ryosuke, Enomoto, Toshiyuki, Ohnuma, Shinobu, Higashijima, Jun, Ozawa, Heita, Ashida, Keigo, Fujita, Fumihiko, Uehara, Keisuke, Maruyama, Satoshi, Ohyama, Masato, Yamamoto, Seiichiro, Hinoi, Takao, Yoshimitsu, Masanori, Okajima, Masazumi, Tanimura, Shu, Kawasaki, Masayasu, Ide, Yoshihito, Hazama, Shoichi, Watanabe, Jun, Inagaki, Daisuke, and Toyokawa, Akihiro

Subjects
medicine.medical_specialty, Colorectal cancer, 03 medical and health sciences, 0302 clinical medicine, intersphincteric resection, medicine, Stage (cooking), rectal cancer, Abdominoperineal resection, business.industry, Confounding, Gastroenterology, sphincter preservation, Original Articles, medicine.disease, Surgery, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Propensity score matching, Cohort, Sphincter, 030211 gastroenterology & hepatology, Observational study, Original Article, local recurrence, business
Abstract

Sphincter‐preserving procedures (SPPs) for surgical treatment of low‐lying rectal tumors have advanced considerably. However, their oncological safety for locally advanced low rectal cancer compared with abdominoperineal resection (APR) is contentious. We retrospectively analyzed cohort data of 1500 consecutive patients who underwent elective resection for stage II‐III rectal cancer between 2010 and 2011. Patients with tumors 2‐5 cm from the anal verge and clinical stage T3‐4 were eligible. Primary outcome was 3‐year local recurrence rate, and confounding effects were minimized by propensity score matching. The study involved 794 patients (456 SPPs and 338 APR). Before matching, candidates for APR were more likely to have lower and advanced lesions, whereas SPPs were carried out more often following preoperative treatment, by laparoscopic approach, and at institutions with higher case volume. After matching, 398 patients (199 each for SPPs and APR) were included in the analysis sample. Postoperative morbidity was similar between the SPPs and APR groups (38% vs 39%; RR 0.98, 95% CI 0.77‐1.27). Margin involvement was present in eight patients in the SPPs group (one and seven at the distal and radial margins, respectively) and in 12 patients in the APR group. No difference in 3‐year local recurrence rate was noted between the two groups (11% vs 14%; HR 0.77, 95% CI 0.42‐1.41). In this observational study, comparability was ensured by adjusting for possible confounding factors. Our results suggest that SPPs and APR for locally advanced low rectal cancer have demonstrably equivalent oncological local control.

Published
2017

19. G-CSF-producing Undifferentiated Pleomorphic Sarcoma Adjacent to the Ascending Colon and in the Right Iliopsoas Muscle: A Case Report and Review of the Literature

Author

Kazama, Shinsuke, primary, Gokita, Tabu, additional, Takano, Michitoshi, additional, Ishikawa, Ayataka, additional, Nishimura, Yu, additional, Ishii, Hiroaki, additional, Nishizawa, Yusuke, additional, Nishimura, Yoji, additional, Kawashima, Yoshiyuki, additional, and Sakamoto, Hirohiko, additional

Published
2019
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20. A randomized controlled trial of the conventional technique versus the no-touch isolation technique for primary tumor resection in patients with colon cancer: Primary analysis of Japan Clinical Oncology Group study JCOG1006.

Author

Takii, Yasumasa, primary, Mizusawa, Junki, additional, Kanemitsu, Yukihide, additional, Komori, Koji, additional, Shiozawa, Manabu, additional, Ohue, Masayuki, additional, Nishimura, Yoji, additional, Ikeda, Satoshi, additional, Takiguchi, Nobuhiro, additional, Kobatake, Takaya, additional, Ike, Hideyuki, additional, Sato, Toshihiko, additional, Tomita, Naohiro, additional, Ota, Mitsuyoshi, additional, and Masaki, Tadahiko, additional

Published
2019
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25. Predictive model for high‐frequency microsatellite instability in colorectal cancer patients over 50 years of age

Author

Fujiyoshi, Kenji, primary, Yamaguchi, Tatsuro, additional, Kakuta, Miho, additional, Takahashi, Akemi, additional, Arai, Yoshiko, additional, Yamada, Mina, additional, Yamamoto, Gou, additional, Ohde, Sachiko, additional, Takao, Misato, additional, Horiguchi, Shin‐ichiro, additional, Natsume, Soichiro, additional, Kazama, Shinsuke, additional, Nishizawa, Yusuke, additional, Nishimura, Yoji, additional, Akagi, Yoshito, additional, Sakamoto, Hirohiko, additional, and Akagi, Kiwamu, additional

Published
2017
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26. Hydronephrosis as a complication of the appendiceal abscess: report of a case

Author

IIDA, Katsuyuki, YAMAGUCHI, Kazumi, NISHIMURA, Yoji, and TOMINAGA, Takashi

Subjects
Hydronephrosis, 494.9, Appendiceal abscess
Abstract

症例は67歳女性で, 1ヵ月ほど前から右腹部痛出現の為来院し, 単純X線像では右腎内に小結石を認めるのみで, 排泄性腎盂造影(IVP)では右水腎症を認めた.精査目的で入院待機中に右側腹部の疝痛発作のため他院泌尿器科に緊急入院し, IVPで上部尿路溢流を合併する右水腎症, 腹部CTで右腎背側の尿貯留腫と骨盤内腫瘤を認めた.前医でのCT検査で右骨盤内尿管腹側に腫瘤を認め, 右尿管はこれより近位で水尿管を呈し, 骨盤内腫瘤と水尿管の接する部位に嵌頓していない尿管結石が認められ, 右腎背側には尿貯留腫を認めた.以上より, 右水腎症は骨盤内腫瘤による圧迫によるもので, 今回そこに結石が下降したため上部尿路外溢流と疝痛発作が起こったものと考えられた.骨盤内腫瘤のCTガイド下針生検結果は慢性炎症細胞の浸潤のみで, 尿貯留腫を伴う骨盤内腫瘍の診断で腫瘍摘出術を施行した.摘出標本の病理組織学的所見から虫垂膿瘍と診断された, We report a case of appendiceal abscess complicated with right hydronephrosis in a 67-year-old woman. She visited our department complaining of right flank pain. Intravenous pyelography (IVP) showed hydronephrosis and hydroureter on right and a narrow ureter at the pelvic brim. A pelvic computed tomographic scan revealed a low density area measuring 44 x 37 mm in size, anterior to the right ureter, which was thought to be a pelvic tumor. Further examination did not reveal the origin of the tumor. An exploratory laparotomy was performed. The tumor developed from the cecum and adhered to the right ureter. The appendix was not found. The tumor was resected with the cecum while the ureter was preserved. Histological investigations revealed an appendiceal abscess. The postoperative course was uneventful. IVP after the operation showed the hydronephrosis to have resolved.

Published
2000

27. Metastatic Pattern of Stage IV Colorectal Cancer with High-Frequency Microsatellite Instability as a Prognostic Factor

Author

FUJIYOSHI, KENJI, primary, YAMAMOTO, GOU, additional, TAKENOYA, TAKASHI, additional, TAKAHASHI, AKEMI, additional, ARAI, YOSHIKO, additional, YAMADA, MINA, additional, KAKUTA, MIHO, additional, YAMAGUCHI, KENSEI, additional, AKAGI, YOSHITO, additional, NISHIMURA, YOJI, additional, SAKAMOTO, HIROHIKO, additional, and AKAGI, KIWAMU, additional

Published
2017
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29. Clinical results of transurethral ureterolithotripsy using pulsed-dye laser: primary ureteral stones versus secondary ureteral stones after ESWL

Author

TANAKA, Michio, YAMAGUCHI, Kazumi, TAKEUCHI, Takumi, NISHIMURA, Yoji, and TOMINAGA, Takashi

Subjects
Efficiency quotient, Transurethral ureterolithotripsy, 494.9, Pulsed-dye laser
Abstract

極細硬性尿管鏡Micro 6及びパルス波ダイレーザー砕石装置Paltholithを用いてTULを施行した. 1)全対象例138例における成功率は82.6%であった. 2)TULを第一選択とした症例における成功率, 残石率はESWL後補助療法で施行された症例よりも良好な傾向にあり, efficiency quotientは0.75であった. 3)U2, U3の下部尿管における成功率はそれぞれ96.0%, 86.2%と良好な結果が得られた. 4)以上より, TULは, U2及びU3の下部尿管結石に対して第一選択治療となりうることが示唆された, Between September 1993 and December 1996, 138 patients underwent transurethral ureterolithotripsy (TUL) either as primary treatment or as a second-line therapy after extracorporeal shock wave lithotripsy. In all patients, a semirigid 6.0 F ureteroscope was used. Lithotripsy was performed using a pulsed-dye laser. The overall success rate was 82.6%. The success rates according to the location of stones were as follows, 76.9% for stones in the upper ureter (U1), 96.0% for those in the midureter (U2), and 86.2% for those in the distal ureter (U3). In 68 patients treated with TUL as primary therapy, the success rate was 88.2% and efficiency quotient, which was modified for TUL was 0.75. Complications were rare: no ureteral perforations and no major bleeding occurred, but urosepsis developed in 2 patients. In conclusion, transurethral ureterolithotripsy using a small caliber ureteroscope with pulsed-dye laser is recommended as the primary treatment for mid- and distal ureteral stones, because of its superior success rate. In addition, for upper ureteral stones, laser tripsy is recommended as a helpful auxiliary procedure.

Published
1998

31. Randomized phase III trial comparing surgery alone to UFT + PSK for stage II rectal cancer (JFMC38 trial).

Author

Okuno, Kiyotaka, Aoyama, Toru, Oba, Koji, Yokoyama, Noboru, Matsuhashi, Nobuhisa, Kunieda, Katsuyuki, Nishimura, Yoji, Akamatsu, Hiroki, Kobatake, Takaya, Morita, Satoshi, Yoshikawa, Takaki, Sakamoto, Junichi, and Saji, Shigetoyo

Subjects
POLYSACCHARIDES, PROGRESSION-free survival, RECTAL cancer treatment, RECTAL cancer patients, COLON cancer diagnosis, COLON cancer treatment, THERAPEUTICS
Abstract

Background: We conducted a randomized phase III trial comparing tegafur/uracil (UFT) and Polysaccharide-K (PSK) to surgery alone in curatively resected stage II rectal cancer patients. Methods: Patients were randomly assigned to receive either UFT and PSK or surgery alone in a 1:1 ratio with a minimization method to balance the treatment allocation. The primary end point of this study was the disease-free survival (DFS). The secondary end point was the overall survival (OS). Results: From October 2011 to February 2013, 111 patients were registered from 62 institutions. The study was prematurely closed due to poor accrual after reaching 20% of its goal. The patients' characteristics were similar between the UFT and PSK group and the surgery-alone group. The DFS rate was 76.0% at 3 years and 65.1% at 5 years in the UFT and PSK arm and 84.0% at 3 years and 77.2% at 5 years in the surgery-alone arm. The DFS was slightly worse in the UFT + PSK arm than in the surgery-alone arm, but the difference did not reach statistical significance (log rank p = 0.102). The OS rate was 100% at 3 years and 97.9% at 5 years in the UFT + PSK arm, while that was 100% at 3 years and 93.4% at 5 years in the surgery-alone arm. The OS was similar in the UFT + PSK arm and surgery-alone arm ( p = 0.533). Conclusion: The present study suggests that UFT and PSK are not attractive candidates to advance to the next phase III study because the DFS was slightly worse in the UFT and PSK arm than in the surgery-alone arm. [ABSTRACT FROM AUTHOR]

Published
2018
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38. A novel and simple KRAS mutation detection method, FRET-Based Preferential Homoduplex Formation Assay (f-PHFA): Results from a multicenter, clinical evaluation trial.

Author

Yamaguchi, Kensei, primary, Akagi, Kiwamu, additional, Kakuta, Miho, additional, Kurosumi, Masafumi, additional, Nishimura, Yoji, additional, Saito, Norio, additional, Kojima, Motohiro, additional, Ochiai, Atsushi, additional, Ohtsu, Atsushi, additional, and Yoshino, Takayuki, additional

Published
2012
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39. Two Cases of Pancreatic Metastasis from Colorectal Cancer

Author

Yamaura, Tadayoshi, primary, Sakamoto, Hirohiko, additional, Yatsuoka, Toshimasa, additional, Kawarabayashi, Nobuaki, additional, Nishimura, Yoji, additional, Amikura, Katsumi, additional, Tanaka, Yoichi, additional, Nishimura, Yuu, additional, and Kurosumi, Masafumi, additional

Published
2011
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41. Three DNA Methylation Epigenotypes in Human Colorectal Cancer

Author

Yagi, Koichi, primary, Akagi, Kiwamu, additional, Hayashi, Hiroshi, additional, Nagae, Genta, additional, Tsuji, Shingo, additional, Isagawa, Takayuki, additional, Midorikawa, Yutaka, additional, Nishimura, Yoji, additional, Sakamoto, Hirohiko, additional, Seto, Yasuyuki, additional, Aburatani, Hiroyuki, additional, and Kaneda, Atsushi, additional

Published
2010
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Author

IIDA, Katsuyuki, YAMAGUCHI, Kazumi, NISHIMURA, Yoji, TOMINAGA, Takashi, IIDA, Katsuyuki, YAMAGUCHI, Kazumi, NISHIMURA, Yoji, and TOMINAGA, Takashi

Abstract

We report a case of appendiceal abscess complicated with right hydronephrosis in a 67-year-old woman. She visited our department complaining of right flank pain. Intravenous pyelography (IVP) showed hydronephrosis and hydroureter on right and a narrow ureter at the pelvic brim. A pelvic computed tomographic scan revealed a low density area measuring 44 x 37 mm in size, anterior to the right ureter, which was thought to be a pelvic tumor. Further examination did not reveal the origin of the tumor. An exploratory laparotomy was performed. The tumor developed from the cecum and adhered to the right ureter. The appendix was not found. The tumor was resected with the cecum while the ureter was preserved. Histological investigations revealed an appendiceal abscess. The postoperative course was uneventful. IVP after the operation showed the hydronephrosis to have resolved.

Published
2000

49. This title is unavailable for guests, please login to see more information.

Author

TANAKA, Michio, YAMAGUCHI, Kazumi, TAKEUCHI, Takumi, NISHIMURA, Yoji, TOMINAGA, Takashi, TANAKA, Michio, YAMAGUCHI, Kazumi, TAKEUCHI, Takumi, NISHIMURA, Yoji, and TOMINAGA, Takashi

Abstract

Between September 1993 and December 1996, 138 patients underwent transurethral ureterolithotripsy (TUL) either as primary treatment or as a second-line therapy after extracorporeal shock wave lithotripsy. In all patients, a semirigid 6.0 F ureteroscope was used. Lithotripsy was performed using a pulsed-dye laser. The overall success rate was 82.6%. The success rates according to the location of stones were as follows, 76.9% for stones in the upper ureter (U1), 96.0% for those in the midureter (U2), and 86.2% for those in the distal ureter (U3). In 68 patients treated with TUL as primary therapy, the success rate was 88.2% and efficiency quotient, which was modified for TUL was 0.75. Complications were rare: no ureteral perforations and no major bleeding occurred, but urosepsis developed in 2 patients. In conclusion, transurethral ureterolithotripsy using a small caliber ureteroscope with pulsed-dye laser is recommended as the primary treatment for mid- and distal ureteral stones, because of its superior success rate. In addition, for upper ureteral stones, laser tripsy is recommended as a helpful auxiliary procedure.

Published
1998

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