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4 results on '"Nino Gogichadze"'

1. Dentists' Perceptions of Mandatory Vaccination for Hepatitis B, Influenza, Measles, and Rubella: A Study in Georgia

Author

Zurab Alkhanishvili, Ketevan Kiguradze-Gogilashvili, Tinatin Svanishvili, Nino Gogichadze, Aleksandre Chkhikvishvili, and Sopio Gvazava

Subjects
hepatitis b, human influenza, measles, rubella, vaccination, Medicine, Dentistry, RK1-715
Abstract

Background and aim: Healthcare workers, including dentists, are at risk of contracting and transmitting infectious diseases despite the availability of vaccines and clear guidelines on preventive measures. In Georgia, hepatitis B, influenza, measles, and rubella are mandatory preventive immunizations for medical personnel employed in dental clinics.Material and methods: This cross-sectional study aimed to explore the knowledge and attitudes of dentists towards vaccination against these diseases. A questionnaire was administered to a selective group of 165 dentists randomly selected from the 2,435 certified dentists with active status in Georgia.Results: The study found that while most dentists were aware of the mandatory vaccines, there were knowledge gaps regarding the potential severe complications of these diseases and the effectiveness of vaccination. Most dentists had positive attitudes towards vaccination, but a significant proportion reported concerns about the safety and efficacy of vaccines.Conclusions: The study highlights the need for continuing education and awareness-raising initiatives among dentists regarding the importance of vaccination against infectious diseases, which could inform future policies and educational programs in dentistry, with the ultimate goal of reducing the transmission of infectious diseases among healthcare workers and patients.

Published
2023
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2. Basic information on Tuberculosis to be shared during communication activities

Author

Nino Gogichadze, Cristina Vilaplana, Arnau Sagrera, Vira Buhiichyk, Joan Pau Millet, Raquel Prieto García, Jesús Edison Ospina, Laura Ginès, Pepón Meneses, Lilibeth Arias, Kaori Levy da Fonseca, Iwona Maciejewska, Eleonora Vianello, Ziyaad Waja, Natasha Pillay, Åsne Dahl, Kjerstin Røstad, Isabelle Saves, Mahavir Singh, and Sergo Vashakidze

Subjects
tuberculosis, communication activities, public health, infectious diseases, general public
Abstract

The SMA-TB Consortium has developed a leaflet with basic information on Tuberculosis to be distributed to general public during communication activities. This leaflet was created within the SMA-TB Project jointly by the IGTP team andthe Public Health Agency of Barcelona (ASPB). The Fundació Lluita contra les Infeccions (Fight Infections Foundation)has also contributed to it,and Laura Ginès and Pepón Meneses illustrated it. Theleaflethas been translated toseveral languagesbymembers of theSMA-TB Consortium partners (all listed as contributors)in order others can reuse it: Catalan Spanish French Italian Portuguese Polish Deutsch Norwegian Ukrainian Georgian Afrikaans Per each language, two versions are provided: one to be printed in a home printer and another one to be printed in a printshop.

Published
2022
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3. Unravelling the transcriptome of the human tuberculosis lesion and its clinical implications

Author

Albert Despuig, Kaori L. Fonseca, Dominic Habgood-Coote, Álvaro Del Río-Álvarez, Juan Carrillo-Reixach, Lilibeth Arias, Nino Gogichadze, Aaron Goff, Leticia Muraro Wildner, Shota Gogishvili, Keti Nikolaishvili, Natalia Shubladze, Zaza Avaliani, Pere-Joan Cardona, Federico Martinón-Torres, Antonio Salas, Alberto Gómez-Carballa, Simon J Waddell, Carolina Armengol, Sergo Vashakidze, Myrsini Kaforou, and Cristina Vilaplana

Abstract

Tuberculosis (TB) disease causes up to 1.5 million deaths every year and represents an important problem of public health at worldwide level. Here, we quantified the gene expression signatures of granuloma biopsies across human TB pulmonary lesions, and validated the best gene candidates using NanoString technology, profiling 157 samples from 40 TB patients who underwent surgery.We characterised the transcriptional profile of the TB granuloma in comparison to healthy tissue, described an 11-gene signature and measured 7 proteins in plasma associated with it. We demonstrated a gradient of immune-related transcript abundance across the granuloma substructure and evidenced metabolically-activeMycobacterium tuberculosisin the lesions. Patients who converted to sputum negative after two months of starting treatment, showed enriched inflammatory pathways in the lesion several months after, supporting use of sputum culture conversion (SCC) as a prognostic biomarker during clinical management and as a factor to prioritise patients when considering lung surgery.

Published
2022

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