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232 results on '"Ninfo, V."'

1. Leiomyosarcoma

Author

Cavazzana, A. O., Ninfo, V., Tirabosco, R., Montaldi, A., Frunzio, R., Berry, C. L., editor, Grundmann, E., editor, Harms, D., editor, and Schmidt, D., editor

Published
1995
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8. Helicobacter Pylori and Gastroesophageal Reflux Disease: a Cross Sectional Study

Author

Angriman, I., D Amico, D. F., Erroi, F., Mescoli, C., Ninfo, V., Norberto, L., Pilon, F., Polese, L., Prando, D., Ruffolo, C., and Marco Scarpa

Subjects
Adult, Chi-Square Distribution, NERD, gastritis, GERD, Middle Aged, Helicobacter Pylori, Abdominal Pain, Helicobacter Infections, Cross-Sectional Studies, Logistic Models, Italy, Gastroesophageal Reflux, Humans, Esophagoscopy, Aged, Retrospective Studies
Abstract

BACKGROUND\Helicobacter Pylori (H. Pylori) is a key pathogenetic factor in gastritis, peptic ulcer disease, gastric carcinoma and lymphoma but its relationship with gastroesophageal reflux disease (GERD) is controversial. The aim of the study is to estimate the possible association between the presence of H. pylori and GERD.In this retrospective study we examined the endoscopy and pathology reports of all the 638 consecutive patients who had upper gastrointestinal endoscopy and adequate mucosal sampling in 2005 in our department at the University of Padova. Yates corrected chi2 test was used to compare the H. Pylori frequency in the different histological groups. Multinomial logistic regression was used to identify possible predictors of H. Pylori infection.In this selected population 133 patients were affected by H. Pylori infection (20.8%) and 107 were affected by GERD according to Montreal definition. No significant relation between H. Pylori infection and GERD or NERD (non erosive reflux disease) was evidenced. As expected histological gastritis at the examination confirmed to be the strongest predictor of infection with a odds ratio of 39.4 (95% CI 5.4-287.4, p0.01). Upper abdominal pain showed to be the only clinical independent predictors for the presence of H. Pylori infection with a odds ratio of 1.5 (95% CI 1.0-2.3, p = 0.04).Our study showed that in north eastern Italy there is no association between H. Pylori infection and GERD. On the contrary presence of histological gastritis and upper abdominal pain were confirmed to be significant predictors of H. Pylori infection. No endoscopic characteristic is significantly related to the presence of H. Pylori.

Published
2011

26. Morphologic Overlap between Infantile Myofibromatosis and Infantile Fibrosarcoma: A Pitfall in Diagnosis

Author

Alaggio, R, Barisani, D, Ninfo, V, Rosolen, A, Coffin, C, Coffin, CM, BARISANI, DONATELLA, Alaggio, R, Barisani, D, Ninfo, V, Rosolen, A, Coffin, C, Coffin, CM, and BARISANI, DONATELLA

Abstract

Infantile myofibromatosis (IM) is a distinctive mesenchymal disorder with different clinical forms, including solitary, multicentric, and generalized with visceral involvement. A wide morphologic spectrum is encountered, with the extremes resembling congenital infantile fibrosarcoma (CIFS) and infantile hemangiopericytoma. We report a series of lesions with mixed features of CIFS and IM and compare them in order to further define their clinicopathologic features and the significance of the so-called composite fibromatosis. Seven lesions with unusual overlapping morphologic "composite" features of both IM and CIFS were selected from a series of 106 myofibroblastic lesions. Three cases classified as composite infantile myofibromatoses (COIM) were highly cellular tumors with a diffuse growth of primitive mesenchymal cells and focal features of IM combined with areas resembling infantile fibrosarcoma (IF). Four caseswere classified as IF. Three of these exhibited a biphasic pattern with foci resembling IM, including whorls of primitive and spindle cells and perivascular and intravascular projections of myofibroblastic nodules, and the 4th had a close histologic resemblance to a primitive, immature IM. With reverse transcriptase polymerase chain reaction, the ETV6-NTRK3 transcript was absent in 3 COIM and was detected in 3 CIFS; the other CIFS had typical cytogenetic aberrations. On the basis of currently available information, COIM represents a morphologic variant of IM that can mimic IF. Careful histologic evaluation to detect the typical features of IM is essential to avoid classification as IF. Molecular analysis for the ETV6-NTRK3 gene fusion is an important diagnostic tool in this group of lesions. © 2008 Society for Pediatric Pathology.

Published
2008

33. Management of primary sarcomas of the retroperitoneum

Author

Carlo Riccardo Rossi, Nitti, D., Foletto, M., Alessio, S., Seno, A., Segato, G., Mancino, G., Marchi, F., Ninfo, V., and Lise, M.

Subjects
Adult, Male, Histiocytoma, Benign Fibrous, Chemotherapy, Adjuvant, Humans, Female, Sarcoma, Retroperitoneal Neoplasms, Middle Aged, Neoplasm Recurrence, Local, Survival Analysis, Neurilemmoma, Aged
Abstract

We here report on our 10-year experience of surgery in 25 patients with primary retroperitoneal sarcoma and make an appraisal of the more effective available clinical approach. Ten patients had leiomyosarcoma, eight liposarcoma, and seven had other tumor types. Histological grading was G1 in seven patients, G2 in six patients and G3 in 12. Ten patients (40%) underwent wide tumor excision, five (20%) marginal excision, four (16%) partial excision and six (24%) wedge biopsy at laparotomy. Adjacent organ resection was required in 10 of the 15 patients who underwent wide or marginal resection, seven of whom had adjuvant chemoradiotherapy. After wide resection, local recurrences were observed in 2/10 patients; the 10-year survival rate was 33%. Three out of five patients who underwent marginal resection had local recurrences; one is alive 10 years after surgery and chemo-radiotherapy. Histological grading was the most important prognostic factor. Radical resection is the only effective available treatment for retroperitoneal sarcomas, and patients with low-grade tumors benefit most from it with respect to survival and local recurrence rate. The efficacy of adjuvant treatment has yet to be clarified.

Published
1993

42. Clinical relevance of DNA ploidy and proliferative activity in childhood rhabdomyosarcoma: a retrospective analysis of patients enrolled onto the Italian Cooperative Rhabdomyosarcoma Study RMS88.

Author

De Zen, L, primary, Sommaggio, A, additional, d'Amore, E S, additional, Masiero, L, additional, di Montezemolo, L C, additional, Linari, A, additional, Madon, E, additional, Dominici, C, additional, Bosco, S, additional, Bisogno, G, additional, Carli, M, additional, Ninfo, V, additional, and Basso, G, additional

Published
1997
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48. Spindle Cell Rhabdomyosarcoma

Author

Cavazzana, A. O., primary, Schmidt, D., additional, Ninfo, V., additional, Harms, D., additional, Tollot, M., additional, Carli, M., additional, Treuner, J., additional, Betto, R., additional, and Salviati, G., additional

Published
1992
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