This letter demonstrates the fabrication of large area molybdenum diselenide (MoSe2) nanoflowers using a simple, cost-effective hydrothermal synthesis followed by vacuum filtration deposition on cellulose paper as a near-infrared region (NIR) light photodetector. An increase in the photocurrent was observed upon increasing intensity of NIR illumination, which could be attributed to the increased number of photogenerated excitons. The fabricated photodetector under the 780 nm wavelength illumination responded to the responsivity and external quantum efficiency (EQE) of the fabricated photodetector of 9.73 mA/W and 0.015%, respectively. Furthermore, even for an arbitrary bending, the fabricated device exhibits a negligible change in the responsivity and EQE, which display the robustness of the fabricated device. Successful fabrication of MoSe2/paper-based flexible, cost-effective, and environment-friendly NIR photodetector holds tremendous applications in future optoelectronic devices.