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3. Gastrointestinal and respiratory morbidity when introducing eggs as complementary food: a randomised controlled trial in South African infants

Author

Regina Nakiranda, Linda Malan, Hannah Ricci, Herculina S. Kruger, Arista Nienaber, Marina Visser, Cristian Ricci, Mieke Faber, and Cornelius M. Smuts

Subjects
Medicine, Science
Abstract

Abstract We investigated the incidence and duration of morbidity symptoms among infants aged 6 to 9 months from a low socioeconomic community receiving one egg daily for 6 months. This was a secondary outcome of a randomised controlled trial (RCT) of 500 infants conducted in Jouberton, South Africa. The primary outcome was linear growth. Morbidity data were collected weekly using a symptoms diary and qualitative data with focus group discussions at the endpoint. Ethical approval was obtained from the North-West University Health Research Ethics Committee. The intervention group had a ~ 5% higher incidence of gastrointestinal morbidity (17.0%) compared to the control group (11.9%). Gastrointestinal morbidity without fever tended to be 1.4 times higher in the intervention group (OR: 1.43, 95% CI: 1.03, 1.93; P = 0.058) and tended to be 4 times higher with fever (OR: 4.07, 95% CI: 0.86, 19.23; P = 0.077). The duration of total gastrointestinal and respiratory morbidity was 1.5 days longer in the intervention group (β: 1.491; 95% CI 0.064, 2.918; P = 0.041). Complementary feeding with eggs may have contributed towards an increased risk for gastrointestinal morbidity.

Published
2024
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4. Disparities in mortality rates from aortic aneurysm and dissection by country-level income status and sexCentral MessagePerspective

Author

Makoto Hibino, MD, MPH, PhD, Nitish K. Dhingra, MD, Raj Verma, Christoph A. Nienaber, MD, Bobby Yanagawa, MD, PhD, and Subodh Verma, MD, PhD

Subjects
aortic disease, mortality trends, income levels, sex difference, Diseases of the circulatory (Cardiovascular) system, RC666-701, Surgery, RD1-811
Abstract

Objective: To investigate the impact of national income level and sex on mortality trends from aortic aneurysm and dissection in addition to all aortic disease as a whole. Methods: Using data from the World Health Organization mortality database, we conducted an analysis of mortality trends from aortic disease between 2000 and 2019, Countries were categorized into middle-income and high-income countries (MICs and HICs) on the basis of income level. Age-standardized and sex-specific age-standardized mortality rates per 100,000 persons, along with male-to-female mortality ratios, were calculated. Trends over the study period were analyzed using joinpoint regression. Results: Our analysis comprised 29 MICs and 46 HICs, with an average population of 595 million and 1042 million during the observation period. During the observation period, age-standardized mortality rates from aortic disease decreased to 2.21 (2.17-2.25) and 2.28 (2.26-2.30) in MICs and HICs, respectively (average annual percentage change of −0.5% in MICs and −1.8% in HICs, P

Published
2024
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5. Predictors of vitamin D status in undernourished and well-nourished children 6–59 months old, in the JB Marks Municipality of South Africa

Author

JA Carboo, L Malan, M Lombard, N Maleka, A Nienaber, and R Claire Dolman-Macleod

Subjects
Vitamin D status, undernutrition, predictors, iron, anaemia, inflammation, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Objective: to investigate the predictors of vitamin D (vitD) status of undernourished and well-nourished children aged under five years in the North West Province of South Africa.Design: this cross-sectional study assessed sociodemographic data, nutritional supplement intake, vitD-rich food consumption, and sunlight exposure via a structured questionnaire. Venous blood samples were collected to evaluate vitD, iron, and inflammatory markers.Setting: the maternal and child wellness departments of six community clinics in the JB Marks Municipality.Participants: 121 undernourished and 51 well-nourished children, 6–59 months old.Results: The prevalence of serum 25(OH)D

Published
2024
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10. Implementation of health-related quality of life in the German TraumaRegister DGU® – first results of a pilot study

Author

Carina Jaekel, Ulrike Nienaber, Anne Neubert, Oliver Kamp, Lisa Wienhöfer, Andre Nohl, Marc Maegele, Helena Duesing, Christoph J. Erichsen, Stephan Frenzel, Rolf Lefering, Sascha Flohe, Dan Bieler, and Outcome Study Group of the Committee on Emergency Medicine, Intensive Care, Trauma Management (Sektion NIS) of the German Trauma Society (DGU)

Subjects
Outcome, Health-related quality of life, Polytrauma, Trauma registry, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

Abstract Background Approximately 30,000 people are affected by severe injuries in Germany each year. Continuous progress in prehospital and hospital care has significantly reduced the mortality of polytrauma patients. With increasing survival rates, the functional outcome, health-related quality (hrQoL) of life and ability to work are now gaining importance. Aim of the study is, the presentation of the response behavior of seriously injured patients on the one hand and the examination of the factors influencing the quality of life and ability to work 12 months after major trauma on the other hand. Building on these initial results, a standard outcome tool shall be integrated in the established TraumaRegister DGU® in the future. Methods In 2018, patients [Injury Severity Score (ISS) ≥ 16; age:18–75 years] underwent multicenter one-year posttraumatic follow-up in six study hospitals. In addition to assessing hrQoL by using the Short-Form Health Survey (SF-12), five additional questions (treatment satisfaction; ability to work; trauma-related medical treatment; relevant physical disability, hrQoL as compared with the prior to injury status) were applied. Results Of the 1,162 patients contacted, 594 responded and were included in the analysis. The post-injury hrQoL does not show statistically significant differences between the sexes. Regarding age, however, the younger the patient at injury, the better the SF-12 physical sum score. Furthermore, the physically perceived quality of life decreases statistically significantly in relation to the severity of the trauma as measured by the ISS, whereas the mentally perceived quality of life shows no differences in terms of injury severity. A large proportion of severely injured patients were very satisfied (42.2%) or satisfied (39.9%) with the treatment outcome. It should be emphasized that patients with a high injury severity (ISS > 50) were on average more often very satisfied with the treatment outcome (46.7%). A total of 429 patients provided information on their ability to work 12 months post-injury. Here, 194 (45.2%) patients had a full employment, and 58 (13.5%) patients were had a restricted employment. Conclusion The present results show the importance of a structured assessment of the postinjury hrQoL and the ability to work after polytrauma. Further studies on the detection of influenceable risk factors on hrQoL and ability to work in the intersectoral course of treatment should follow to enable the best possible outcome of polytrauma survivors.

Published
2024
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12. Sustainability initiatives in inpatient psychiatry: tackling food waste

Author

Timur Liwinski, Iona Bocek, Andreas Schmidt, Eva Kowalinski, Frieder Dechent, Franziska Rabenschlag, Julian Moeller, Jan Sarlon, Annette B. Brühl, André Nienaber, Undine E. Lang, and Christian G. Huber

Subjects
food waste, hospital waste, health care sustainability, environmental sustainability, environmental stressors, water usage, Psychiatry, RC435-571
Abstract

BackgroundFood plays a dual role in promoting human health and environmental sustainability. Yet, current food systems jeopardize both. Food waste poses a major global challenge due to its significant economic, social, and environmental impacts. Healthcare facilities generate the largest amounts of food waste compared to other forms of catering provision. Food waste correlates with environmental unsustainability and diminished patient satisfaction, compounding the prevalent challenge of hospital malnutrition and contributing to suboptimal patient outcomes.Materials and methodsIn a three-year interventional study (2020-2022) at a psychiatric tertiary care center, we assessed and mitigated food waste using evidence-based measures. We conducted systematic food wastage audits over three years (2020-2022) in May and June, each lasting four weeks. Costs were analyzed comprehensively, covering food, staff, infrastructure, and disposal. Environmental impact was assessed using Umweltbelastungspunkte (UBP) and CO2e/kg emissions, alongside water usage (H2O - l/kg).ResultsEconomic losses due to food wastage were substantial, primarily from untouched plates and partially consumed dinners, prompting meal planning adjustments. Despite a >3% increase in meals served, both food waste mass and costs decreased by nearly 6%. Environmental impact indicators showed a reduction >20%. Vegetables, salad, and fruits constituted a significant portion of waste. Overproduction minimally contributed to waste, validating portion control efficacy.ConclusionOur study highlights significant economic and environmental losses due to hospital food waste, emphasizing the importance of resource efficiency. The strategies outlined offer promising avenues for enhanced efficiency. The decrease in food waste observed over the three-year period underscores the potential for improvement.

Published
2024
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13. Micronutrient supplementation practices in relation to the World Health Organisation 2013 guidelines on management of severe acute malnutrition

Author

Doris Cement Nanga, Janet A. Carboo, Humphrey Chatenga, Arista Nienaber, Cornelia Conradie, Martani Lombard, and Robin Claire Dolman‐Macleod

Subjects
micronutrient deficiency, severe acute malnutrition, supplementation, therapeutic feeds, under‐5 children, WHO guidelines, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Abstract In 2013, the World Health Organisation (WHO) updated the recommendations for micronutrient deficiency correction in hospitalised under‐5 children with complicated severe acute malnutrition (SAM). This study aimed to describe the micronutrient deficiency correction practices in relation to WHO 2013 recommendations. Data from medical records of under‐5 children admitted for SAM management at two hospitals in South Africa and three tertiary hospitals in Ghana were extracted. Micronutrient correction practices were compared to the WHO 2013 recommendations by considering the dosage, timing of micronutrient supplementation (vitamin A, iron and folic acid) and therapeutic feeds administered. In total, 723 medical records were included. Nearly half (48.3%) of the children received at least one of the studied micronutrients as a supplement. Vitamin A was supplemented in 27.4% of the children, while iron and folic acid were supplemented in 9.5% and 34.9%, respectively. Among the children who received vitamin A, 60.1% received the first dose on Day 1 of admission. Also, 46.4% of the iron‐supplemented children received iron within the first week of admission. Vitamin A, iron and folic acid were administered within the dose range of 100,000–180,000 IU, 3.1–7.7 mg per kg per day, and 3–5 mg per day, respectively. Additionally, 71.7% of the children reportedly received therapeutic feeds that met WHO recommendations. The micronutrient deficiency correction practices regarding dose and timing differed from the 2013 WHO guidelines. Qualitative studies investigating the reasons for the disparities are recommended.

Published
2024
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14. Modelling years of life lost due to acute type A aortic dissection in the German healthcare setting: a predictive study

Author

Christoph A Nienaber, Alexander Meyer, Volkmar Falk, Philipp Schiele, Adriana N König, and Stephan D Kurz

Subjects
Medicine
Abstract

Objectives This study aimed to develop a patient-centred approach to the burden of acute type A aortic dissection (ATAAD) through modelling. The main objective was to identify potential improvements in managing this life-threatening cardiovascular condition and to provide evidence-based recommendations to optimise outcomes.Design We developed a predictive model along patient pathways to estimate the burden of ATAAD through the years of life lost (YLLs) metric. The model was created based on a systematic review of the literature and was parameterised using demographic data from the German healthcare environment. The model was designed to allow interactive simulation of different scenarios resulting from changes in key impact factors.Setting The study was conducted using data from the German healthcare environment and results from the literature review.Participants The study included a comprehensive modelling of ATAAD cases in Germany but did not directly involve participants.Interventions There were no specific interventions applied in this study based on the modelling design.Primary and secondary outcome measures The single outcome measure was the estimation of YLL due to ATAAD in Germany.Results Our model estimated 102 791 YLL per year for ATAAD in Germany, with 62 432 and 40 359 YLL for men and women, respectively. Modelling an improved care setting yielded 93 191 YLL or 9.3% less YLL compared with the current standard while a worst-case scenario resulted in 113 023 or 10.0% more YLL. The model is accessible at https://acuteaorticdissection.com/ to estimate custom scenarios.Conclusions Our study provides an evidence-based approach to estimating the burden of ATAAD and identifying potential improvements in the management of pathways. This approach can be used by healthcare decision-makers to inform policy changes aimed at optimising patient outcomes. By considering patient-centred approaches in any healthcare environment, the model has the potential to improve efficient care for patients suffering from ATAAD.

Published
2024
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15. Scalar field damping at high temperatures

Author

Bodeker, Dietrich and Nienaber, Jan

Subjects
High Energy Physics - Phenomenology, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The motion of a scalar field that interacts with a hot plasma, like the inflaton during reheating, is damped, which is a dissipative process. At high temperatures the damping can be described by a local term in the effective equation of motion. The damping coefficient is sensitive to multiple scattering. In the loop expansion its computation would require an all-order resummation. Instead we solve an effective Boltzmann equation, similarly to the computation of transport coefficients. For an interaction with another scalar field we obtain a simple relation between the damping coefficient and the bulk viscosity, so that one can make use of known results for the latter. The numerical prefactor of the damping coefficient turns out to be rather large, of order $ 10 ^ 4 $., Comment: 18 pages, explanations and some details added, references added, (non-)role of scale-invariance violation clarified, results unchanged. Closely resembles published version

Published
2022
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18. The Funny Thing Is, Instructor Humor Style Affects Likelihood of Student Engagement

Author

Nienaber, Kristie, Abrams, Gwyneth, and Segrist, Dan

Abstract

Instructors often use humor in teaching their classes. Research suggests that humor can affect how instructors and their teaching are perceived. The current study examined whether the type of humor used by a hypothetical instructor and instructor gender affected the perceived likelihood of engaging with the instructor. College students read a vignette describing the teaching and humor used by a hypothetical instructor. The likelihood that students would engage with the instructor was highest when the instructor's humor style was good-natured and lowest when it was hostile and sarcastic. Instructor gender had no effect on students' likelihood of engaging with the instructor.

Published
2019

21. Double transition of young migrants in Luxembourg: vulnerable, resilient and empowering integration trajectories in the period of youth

Author

José Oliveira, Birte Nienaber, Jutta Bissinger, Amalia Gilodi, Catherine Richard, and Isabelle Albert

Subjects
young migrants, integration, vulnerability, resilience, empowerment, Sociology (General), HM401-1281
Abstract

Migrant integration trajectories have become more complex, open, uncertain, and continuously changing, over time. For young migrants, their integration endeavour intersects with their process of transition to adulthood, a double transition that poses additional challenges. Recent theoretical perspectives such as “liquid integration” aim at focusing on the dynamic, processual, and temporal nature of migrant integration. The present article focuses on the dynamic interplay of obstacles and enablers that, over time, interact to construct complex, often non-linear, and open-ended integration and coming of age trajectories of young migrants (aged from 18 to 30 years) coming from outside the European Union (EU) to EU countries. Empirical results from the H2020 MIMY (Empowerment through liquid Integration of Migrant Youth in vulnerable conditions) research project in Luxembourg will be presented. In order to address the goal of the research, qualitative data were gathered by means of N = 38 interviews with young migrants with different migratory paths, characteristics and experiences, and specifically included: young migrants from non-EU Portuguese-speaking countries (N = 16), refugees living in reception centres (N = 15), migrants who since arriving in Luxembourg have become publicly visible (N = 7). Content analysis of the interviews allowed a twofold purpose: (1) capturing the unfolding of intersectional integration obstacles that over time play a decisive role in the building of conditions of vulnerability of the double transition under analysis; (2) capturing the multidimensional resources that interactively build up to give rise to resilient and empowering integration and coming of age experiences. The identification of decisive multidimensional obstacles and resources present in the integration endeavour during the process of coming of age allowed us to capture differentiated routes of vulnerability, on the one hand, and resilience/ empowerment on the other. Key ingredients of both vulnerable and more resilient and empowering integration and coming of age trajectories are identified as well as their relational dynamics, enabling to address key challenges for the resilience and empowerment of young migrants in the process of negotiating their transition to adulthood amidst their integration challenges in the Luxembourgish society.

Published
2024
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22. Transcaval Transcatheter Aortic Valve Replacement for Pure Aortic Regurgitation Using a Dedicated Self-Expanding Device

Author

Jonathan Curio, MD, Stephan Nienaber, MD, Elmar W. Kuhn, MD, Kaveh Eghbalzadeh, MD, Wael Ahmad, MD, Arash Mehdiani, MD, Jörg Schröder, MD, Maria Isabel Körber, MD, Hendrik Wienemann, MD, Stephan Baldus, MD, and Matti Adam, MD

Subjects
alternative access, aortic regurgitation, electrosurgery, TAVR, transcaval, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Novel dedicated devices allow transcatheter treatment of pure aortic regurgitation (AR). The JenaValve Trilogy Heart Valve System was introduced as the first dedicated and on-label AR transcatheter aortic valve replacement system, implementing a locator-based and calcium-independent anchoring mechanism. Here, we present the first-in-human transcatheter aortic valve replacement for pure AR via a transcaval access in a patient with prohibitive alternative arterial accesses.

Published
2024
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23. Understanding the corrosion of Mg alloys in in vitro urinary tract conditions: A step forward towards a biodegradable metallic ureteral stent

Author

Margarida Pacheco, Ivo M. Aroso, Joana M. Silva, Sviatlana V. Lamaka, Jan Bohlen, Maria Nienaber, Dietmar Letzig, Estêvão Lima, Alexandre A. Barros, and Rui L. Reis

Subjects
Biodegradable metals, Magnesium alloys, Localized corrosion, Biodegradable metallic ureteral stent, Mining engineering. Metallurgy, TN1-997
Abstract

Ureteral stents play a fundamental role in modern time urology. However, following the deployment, stent-related symptoms are frequent and affect patient health and quality of life. Using biodegradable metals as ureteral stent materials have emerged as a promising strategy, mainly due to the improved radial force and slower degradation rate expected. Therefore, this study aimed to characterize different biodegradable metals in urinary tract environment to understand their propensity for future utilization as base materials for ureteral stents. The corrosion of 5 Mg alloys – AZ31, Mg-1Zn, Mg-1Y, pure Mg, and Mg-4Ag – under simulated urinary tract conditions was accessed. The corrosion layer of the different alloys presented common elements, such as Mg(OH)2, MgO, and phosphate-containing products, but slight variations in their chemical compositions were detected. The corrosion rate of the different metals varied, which was expected given the differences in the corrosion layers. On top of this, the findings of this study highlighted the significant differences in the samples' corrosion and corrosion layers when in stagnant and flowing conditions. With the results of this study, we concluded that Mg-1Zn and Mg-4Ag presented a higher propensity for localized corrosion, probably due to a less protective corrosion layer; Mg-4Ag corroded faster than all the other four alloys, and Mg-1Y stood out due to its distinct corrosion pattern, that showed to be more homogeneous than all the other four samples, making this one more attractive for the future studies on biodegradable metals.

Published
2023
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24. Influence of Ca addition on the dynamic and static recrystallization behavior of direct extruded flat profiles of Mg-Y-Zn alloy

Author

Maria Nienaber, Jan Bohlen, Sangbong Yi, Gerrit Kurz, Karl Ulrich Kainer, and Dietmar Letzig

Subjects
Extrusion, Recrystallization, Magnesium alloy, Mg-Y-Zn-Ca alloy, Formability, quadrupole texture, Mining engineering. Metallurgy, TN1-997
Abstract

This paper investigates the influence of addition of Ca in a Y-Zn-containing magnesium alloy on the dynamic and static recrystallization behaviors and reveals the formation mechanism of the quadrupole texture during thermomechanical processing. Direct extrusion of flat bands has been conducted at various process conditions to study the difference between the two alloys WZ10 and WZX100 in terms of microstructure and texture development. It can be shown that, Ca addition promotes the DRX of WZ10 alloy. During additional heat treatment, the absence of Y segregation at the grain boundaries and the associated lack of solute drag to the boundary mobility leads to a pronounced grain growth during SRX in WZX100 alloy. Furthermore, it is shown that the addition of Ca to Y-Zn is not beneficial in terms of formability. It is demonstrated that alloying elements can have different effects depending on the recrystallization mechanisms. Partially recrystallized microstructure is a prerequisite at the as-extruded status to form the quadrupole texture and during subsequent annealing, which stands for high formability.

Published
2023
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25. Cosmic Ray Background Rejection with Wire-Cell LArTPC Event Reconstruction in the MicroBooNE Detector

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Ge, G., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, W., Guenette, R., Guzowski, P., Hagaman, L., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Kaneshige, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Lepin, L. Mora, Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thorpe, C., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yandel, E., Yang, T., Yarbrough, G., Yates, L. E., Yu, H. W., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

For a large liquid argon time projection chamber (LArTPC) operating on or near the Earth's surface to detect neutrino interactions, the rejection of cosmogenic background is a critical and challenging task because of the large cosmic ray flux and the long drift time of the TPC. We introduce a superior cosmic background rejection procedure based on the Wire-Cell three-dimensional (3D) event reconstruction for LArTPCs. From an initial 1:20,000 neutrino to cosmic-ray background ratio, we demonstrate these tools on data from the MicroBooNE experiment and create a high performance generic neutrino event selection with a cosmic contamination of 14.9\% (9.7\%) for a visible energy region greater than O(200)~MeV. The neutrino interaction selection efficiency is 80.4\% and 87.6\% for inclusive $\nu_\mu$ charged-current and $\nu_e$ charged-current interactions, respectively. This significantly improved performance compared to existing reconstruction algorithms, marks a major milestone toward reaching the scientific goals of LArTPC neutrino oscillation experiments operating near the Earth's surface.

Published
2021
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26. Measurement of the Flux-Averaged Inclusive Charged-Current Electron Neutrino and Antineutrino Cross Section on Argon using the NuMI Beam and the MicroBooNE Detector

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Dennis, S. R., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Ge, G., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, W., Guenette, R., Guzowski, P., Hagaman, L., Hall, E., Hamilton, P., Hen, O., Hill, C., Horton-Smith, G. A., Hourlier, A., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Kaneshige, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Lepin, L. Mora, Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thorpe, C., Toups, M., Tsai, Y. -T., Uchida, M. A., Usher, T., Van De Pontseele, W., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yandel, E., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
High Energy Physics - Experiment
Abstract

We present a measurement of the combined $\nu_e$ + $\bar{\nu}_e$ flux-averaged charged-current inclusive cross section on argon using data from the MicroBooNE liquid argon time projection chamber (LArTPC) at Fermilab. Using the off-axis flux from the NuMI beam, MicroBooNE has reconstructed 214 candidate $\nu_e$ + $\bar{\nu}_e$ interactions with an estimated exposure of 2.4$\times10^{20}$ protons on target. Given the estimated purity of 38.6\%, this implies the observation of 80 $\nu_e$ + $\bar{\nu}_e$ events in argon, the largest such sample to date. The analysis includes the first demonstration of a fully automated application of a dE/dx-based particle discrimination technique of electron and photon induced showers in a LArTPC neutrino detector. We measure the $\nu_e + \bar{\nu}_e$ flux-averaged charged-current total cross section to be ${6.84\pm\!1.51~\textrm{(stat.)}\pm\!2.33~\textrm{(sys.)}\!\times\!10^{-39}~\textrm{cm}^{2}/~\textrm{nucleon}}$, for neutrino energies above 250 MeV and an average neutrino flux energy of 905 MeV when this threshold is applied. The measurement is sensitive to neutrino events where the final state electron momentum is above 48 MeV/c, includes the entire angular phase space of the electron, and is in agreement with the theoretical predictions from \texttt{GENIE} and \texttt{NuWro}. This measurement is also the first demonstration of electron neutrino reconstruction in a surface LArTPC in the presence of cosmic ray backgrounds, which will be a crucial task for surface experiments like those that comprise the Short-Baseline Neutrino (SBN) Program at Fermilab., Comment: 16 pages, 16 figures, contains supplementary flux files

Published
2021
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27. Measurement of the Atmospheric Muon Rate with the MicroBooNE Liquid Argon TPC

Author

MicroBooNE collaboration, Adams, C., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bass, M., Bay, F., Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Carr, R., Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Cohen, E. O., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diaz, A., Domine, L., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Genty, V., Goeldi, D., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Grosso, R., Gu, L., Gu, W., Guenette, R., Guzowski, P., Hamilton, P., Hen, O., Hill, C., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Joshi, J., Jwa, Y. J., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., Lepetic, I., Li, Y., Lister, A., Littlejohn, B. R., Lockwitz, S., Lorca, D., Louis, W. C., Luethi, M., Lundberg, B., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moore, C. D., Mousseau, J., Murphy, M., Murrells, R., Naples, D., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Pandey, V., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Porzio, D., Prince, S., Pulliam, G., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Ren, L., Rochester, L., Rogers, H. E., Ross-Lonergan, M., von Rohr, C. Rudolf, Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thornton, R. T., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., Weber, M., Wei, H., Wickremasinghe, D. A., Williams, Z., Wolbers, S., Wongjirad, T., Woodruff, K., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

MicroBooNE is a near-surface liquid argon (LAr) time projection chamber (TPC) located at Fermilab. We measure the characterisation of muons originating from cosmic interactions in the atmosphere using both the charge collection and light readout detectors. The data is compared with the CORSIKA cosmic-ray simulation. Good agreement is found between the observation, simulation and previous results. Furthermore, the angular resolution of the reconstructed muons inside the TPC is studied in simulation., Comment: 20 pages, 14 figures

Published
2020
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28. Semantic Segmentation with a Sparse Convolutional Neural Network for Event Reconstruction in MicroBooNE

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Dennis, S. R., Devitt, D., Diurba, R., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Ge, G., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, W., Guenette, R., Guzowski, P., Hagaman, L., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Kaneshige, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Louis, W. C., Luo, X., Marchionni, A., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Lepin, L. Mora, Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thorpe, C., Toups, M., Tsai, Y. -T., Uchida, M. A., Usher, T., Van De Pontseele, W., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yandel, E., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

We present the performance of a semantic segmentation network, SparseSSNet, that provides pixel-level classification of MicroBooNE data. The MicroBooNE experiment employs a liquid argon time projection chamber for the study of neutrino properties and interactions. SparseSSNet is a submanifold sparse convolutional neural network, which provides the initial machine learning based algorithm utilized in one of MicroBooNE's $\nu_e$-appearance oscillation analyses. The network is trained to categorize pixels into five classes, which are re-classified into two classes more relevant to the current analysis. The output of SparseSSNet is a key input in further analysis steps. This technique, used for the first time in liquid argon time projection chambers data and is an improvement compared to a previously used convolutional neural network, both in accuracy and computing resource utilization. The accuracy achieved on the test sample is $\geq 99\%$. For full neutrino interaction simulations, the time for processing one image is $\approx$ 0.5 sec, the memory usage is at 1 GB level, which allows utilization of most typical CPU worker machine.

Published
2020
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29. High-performance Generic Neutrino Detection in a LArTPC near the Earth's Surface with the MicroBooNE Detector

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Ge, G., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, W., Guenette, R., Guzowski, P., Hagaman, L., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Kaneshige, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Lepin, L. Mora, Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thorpe, C., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yandel, E., Yang, T., Yarbrough, G., Yates, L. E., Yu, H. W., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

Large Liquid Argon Time Projection Chambers (LArTPCs) are being increasingly adopted in neutrino oscillation experiments because of their superb imaging capabilities through the combination of both tracking and calorimetry in a fully active volume. Active LArTPC neutrino detectors at or near the Earth's surface, such as the MicroBooNE experiment, present a unique analysis challenge because of the large flux of cosmic-ray muons and the slow drift of ionization electrons. We present a novel Wire-Cell-based high-performance generic neutrino-detection technique implemented in MicroBooNE. The cosmic-ray background is reduced by a factor of 1.4$\times10^{5}$ resulting in a 9.7\% cosmic contamination in the selected neutrino candidate events, for visible energies greater than 200~MeV, while the neutrino signal efficiency is retained at 88.4\% for $\nu_{\mu}$ charged-current interactions in the fiducial volume in the same energy region. This significantly improved performance compared to existing reconstruction algorithms, marks a major milestone toward reaching the scientific goals of LArTPC neutrino oscillation experiments operating near the Earth's surface., Comment: 8 pages, 2 figures

Published
2020
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30. Development and first results of a national databank on care and treatment outcome after traumatic brain injury

Author

Younsi, Alexander, Unterberg, Andreas, Marzi, Ingo, Steudel, Wolf-Ingo, Uhl, Eberhard, Lemcke, Johannes, Berg, Florian, Woschek, Mathias, Friedrich, Michaela, Clusmann, Hans, Hamou, Hussam Aldin, Mauer, Uwe Max, Scheer, Magnus, Meixensberger, Jürgen, Lindner, Dirk, Schmieder, Kirsten, Gierthmuehlen, Mortimer, Hoefer, Christine, Nienaber, Ulrike, and Maegele, Marc

Published
2023
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31. Shielding AZ91D-1%Ca from corrosion through ultrasound melt treatment: A study for stent design

Author

I.V. Gomes, M. Pacheco, M. Nienaber, S.C. Neves, D. Mei, A. Barros, R.L. Reis, J.L. Alves, and H. Puga

Subjects
Magnesium, Ultrasound treatment, Stent, Corrosion, Mechanical properties, Mining engineering. Metallurgy, TN1-997
Abstract

Magnesium-based materials show great potential for producing biodegradable stents, but their high corrosion rates are a roadblock.This study investigates whether ultrasound melt treatment can change the corrosion response of an extruded AZ91D-1.0%Ca (wt.%) in Earle's Balanced Salt Solution by tailoring the intermetallics' morphology in the as-extruded state.The results showed that the wires from ultrasound-treated ingots corroded faster than non-treated ones in immersion for up to 6 hours. This trend shifted for longer periods, and ultrasound-treated material showed lower corrosion rates and uniform corrosion, while the non-treated material displayed localized corrosion signs. Tensile testing of the wires demonstrated that immersion in EBSS lowered the tensile strength and elongation at fracture due to material degradation, regardless of the processing route. Nonetheless, this decline was sharper in the non-treated material.These findings suggest that ultrasound melt processing can be a promising method for improving the corrosion resistance of magnesium-based materials, paving the way for their use in manufacturing biodegradable stents.

Published
2023
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32. Contrasting MEG effects of anodal and cathodal high-definition TDCS on sensorimotor activity during voluntary finger movements

Author

Jed A. Meltzer, Gayatri Sivaratnam, Tiffany Deschamps, Maryam Zadeh, Catherine Li, Faranak Farzan, and Alex Francois-Nienaber

Subjects
magnetoencephalography (MEG), TDCS, MCRF, polarity, beta oscillations, gamma oscillations, Neurology. Diseases of the nervous system, RC346-429
Abstract

IntroductionProtocols for noninvasive brain stimulation (NIBS) are generally categorized as “excitatory” or “inhibitory” based on their ability to produce short-term modulation of motor-evoked potentials (MEPs) in peripheral muscles, when applied to motor cortex. Anodal and cathodal stimulation are widely considered excitatory and inhibitory, respectively, on this basis. However, it is poorly understood whether such polarity-dependent changes apply for neural signals generated during task performance, at rest, or in response to sensory stimulation.MethodsTo characterize such changes, we measured spontaneous and movement-related neural activity with magnetoencephalography (MEG) before and after high-definition transcranial direct-current stimulation (HD-TDCS) of the left motor cortex (M1), while participants performed simple finger movements with the left and right hands.ResultsAnodal HD-TDCS (excitatory) decreased the movement-related cortical fields (MRCF) localized to left M1 during contralateral right finger movements while cathodal HD-TDCS (inhibitory), increased them. In contrast, oscillatory signatures of voluntary motor output were not differentially affected by the two stimulation protocols, and tended to decrease in magnitude over the course of the experiment regardless. Spontaneous resting state oscillations were not affected either.DiscussionMRCFs are thought to reflect reafferent proprioceptive input to motor cortex following movements. Thus, these results suggest that processing of incoming sensory information may be affected by TDCS in a polarity-dependent manner that is opposite that seen for MEPs—increases in cortical excitability as defined by MEPs may correspond to reduced responses to afferent input, and vice-versa.

Published
2024
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33. Implementation of a Budo group therapy for psychiatric in- and outpatients: a feasibility study

Author

Jasprit Singh, Karl Jawhari, Mariela Jaffé, Lukas Imfeld, Franziska Rabenschlag, Julian Moeller, André Nienaber, Undine E. Lang, and Christian G. Huber

Subjects
mental health, physical exercise, martial arts, group therapy, resilience, Psychiatry, RC435-571
Abstract

IntroductionPhysical exercise has been shown to have numerous health benefits on co-morbid somatic conditions in psychiatry and can also enhance mental health. Thus, it is not difficult to recommend physical training programs as part of an integrated and holistic treatment approach for mental health disorders. However, getting patients to participate and keeping them engaged is a major challenge. Programs based on martial arts training could be interventions improving physical and mental health with higher attachment rates. The structured discipline, holistic approach integrating physical and mental elements, and empowering activities, may explain higher participant attachment rates.MethodsThus, the main objective of this feasibility study is to describe a newly established group therapy program incorporating interventions from martial arts training with its physical and philosophical parts including mindfulness and breath work.ResultsDuring the 14-month study period from April 2021 to May 2022, a Budo group therapy was used by 215 individual persons with a total of 725 group therapy participations. Retention in the program was good across all settings and very good for persons who participated as outpatients. The mean age of the participants was 33.5 years with a range from 14 to 69 years of age, and about 41% of the participants were female. The therapy program was able to address patients over the whole spectrum of psychiatric diagnoses. Satisfaction and motivation were uniformly self-reported as very good. Patients self-reported improved mental and physical health after participating in a Budo session compared to pre-session.DiscussionBudo group therapy thus can be seen as a feasible, well-accepted and promising new transdiagnostic treatment approach, combining physical activation with resilience enhancement. With minimal contraindications, a broad spectrum of individuals seeking mental health support can engage in this group therapy.

Published
2024
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34. Work-related participation impairments and support needs of patients in a Swiss psychiatric university hospital

Author

Niki Hug, Lukas Imfeld, Benjamin Holinger, Dorothea Jäckel, Christian G. Huber, and André Nienaber

Subjects
work-related participation, return to work, inpatient psychiatric treatment, psychiatric disorder, job coaching, Psychiatry, RC435-571
Abstract

ObjectiveTo assess work-related participation impairments and support needs of adult patients in inpatient and day-care treatment at a Swiss psychiatric university hospital.MethodologyCross-sectional survey on a department-dependent cut-off date in May and June 2022 using a standardized structured interview.ResultsData were available for 93 patients (response rate 59%), of which 51% (n = 47) stated that they had a job or training place. Patients in first hospitalization and with a job or training place were approached significantly more often. Regardless of age and first hospitalization, 76% of the patients expressed a need for support, of which 92% expressed interest in job coaching. A total of 54% of the patients stated that they had received support from the treatment team.ConclusionFrom the patients’ point of view, work and education were not addressed by the treatment team across the board and independently of patient characteristics. The need for support was insufficiently met. There is a considerable interest for support programs through job coaching, and this offers opportunities to promote the inclusion of patients in the regular labor market.

Published
2024
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35. Neutrino Event Selection in the MicroBooNE Liquid Argon Time Projection Chamber using Wire-Cell 3-D Imaging, Clustering, and Charge-Light Matching

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Ge, G., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, W., Guenette, R., Guzowski, P., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thorpe, C., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Yu, H. W., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

An accurate and efficient event reconstruction is required to realize the full scientific capability of liquid argon time projection chambers (LArTPCs). The current and future neutrino experiments that rely on massive LArTPCs create a need for new ideas and reconstruction approaches. Wire-Cell, proposed in recent years, is a novel tomographic event reconstruction method for LArTPCs. The Wire-Cell 3D imaging approach capitalizes on charge, sparsity, time, and geometry information to reconstruct a topology-agnostic 3D image of the ionization electrons prior to pattern recognition. A second novel method, the many-to-many charge-light matching, then pairs the TPC charge activity to the detected scintillation light signal, thus enabling a powerful rejection of cosmic-ray muons in the MicroBooNE detector. A robust processing of the scintillation light signal and an appropriate clustering of the reconstructed 3D image are fundamental to this technique. In this paper, we describe the principles and algorithms of these techniques and their successful application in the MicroBooNE experiment. A quantitative evaluation of the performance of these techniques is presented. Using these techniques, a 95% efficient pre-selection of neutrino charged-current events is achieved with a 30-fold reduction of non-beam-coincident cosmic-ray muons, and about 80\% of the selected neutrino charged-current events are reconstructed with at least 70% completeness and 80% purity.

Published
2020
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36. A Convolutional Neural Network for Multiple Particle Identification in the MicroBooNE Liquid Argon Time Projection Chamber

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Dennis, S., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Ge, G., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, W., Guenette, R., Guzowski, P., Hagaman, L., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Kaneshige, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Lepin, L. Mora, Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thorpe, C., Toups, M., Tsai, Y. -T., Uchida, M. A., Usher, T., Van De Pontseele, W., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yandel, E., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
High Energy Physics - Experiment
Abstract

We present the multiple particle identification (MPID) network, a convolutional neural network (CNN) for multiple object classification, developed by MicroBooNE. MPID provides the probabilities of $e^-$, $\gamma$, $\mu^-$, $\pi^\pm$, and protons in a single liquid argon time projection chamber (LArTPC) readout plane. The network extends the single particle identification network previously developed by MicroBooNE. MPID takes as input an image either cropped around a reconstructed interaction vertex or containing only activity connected to a reconstructed vertex, therefore relieving the tool from inefficiencies in vertex finding and particle clustering. The network serves as an important component in MicroBooNE's deep learning based $\nu_e$ search analysis. In this paper, we present the network's design, training, and performance on simulation and data from the MicroBooNE detector.

Published
2020
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37. Measurement of Differential Cross Sections for $\nu_\mu$-Ar Charged-Current Interactions with Protons and no Pions in the Final State with the MicroBooNE Detector

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Ge, G., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, W., Guenette, R., Guzowski, P., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Lister, A., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thorpe, C., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology, Nuclear Experiment, Nuclear Theory, Physics - Instrumentation and Detectors
Abstract

We present an analysis of MicroBooNE data with a signature of one muon, no pions, and at least one proton above a momentum threshold of 300 MeV/c (CC0$\pi$Np). This is the first differential cross section measurement of this topology in neutrino-argon interactions. We achieve a significantly lower proton momentum threshold than previous carbon and scintillator-based experiments. Using data collected from a total of approximately $1.6 \times 10^{20}$ protons-on-target, we measure the muon neutrino cross section for the CC0$\pi$Np interaction channel in argon at MicroBooNE in the Booster Neutrino Beam which has a mean energy of around 800 MeV. We present the results from a data sample with estimated efficiency of 29\% and purity of 76\% as differential cross sections in five reconstructed variables: the muon momentum and polar angle, the leading proton momentum and polar angle, and the muon-proton opening angle. We include smearing matrices that can be used to "forward-fold" theoretical predictions for comparison with these data. We compare the measured differential cross sections to a number of recent theory predictions demonstrating largely good agreement with this first-ever data set on argon., Comment: 24 pages, 43 figures, 1 table and supplemental material

Published
2020
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38. The Continuous Readout Stream of the MicroBooNE Liquid Argon Time Projection Chamber for Detection of Supernova Burst Neutrinos

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Cohen, E. O., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Fadeeva, A. A., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, L., Gu, W., Guenette, R., Guzowski, P., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thornton, R. T., Thorpe, C., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The MicroBooNE continuous readout stream is a parallel readout of the MicroBooNE liquid argon time projection chamber (LArTPC) which enables detection of non-beam events such as those from a supernova neutrino burst. The low energies of the supernova neutrinos and the intense cosmic-ray background flux due to the near-surface detector location makes triggering on these events very challenging. Instead, MicroBooNE relies on a delayed trigger generated by SNEWS (the Supernova Early Warning System) for detecting supernova neutrinos. The continuous readout of the LArTPC generates large data volumes, and requires the use of real-time compression algorithms (zero suppression and Huffman compression) implemented in an FPGA (field-programmable gate array) in the readout electronics. We present the results of the optimization of the data reduction algorithms, and their operational performance. To demonstrate the capability of the continuous stream to detect low-energy electrons, a sample of Michel electrons from stopping cosmic-ray muons is reconstructed and compared to a similar sample from the lossless triggered readout stream., Comment: 30 pages, 21 figures

Published
2020
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39. Measurement of Space Charge Effects in the MicroBooNE LArTPC Using Cosmic Muons

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Cohen, E. O., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, L., Gu, W., Guenette, R., Guzowski, P., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Kamp, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marsden, D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thornton, R. T., Thorpe, C., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

Large liquid argon time projection chambers (LArTPCs), especially those operating near the surface, are susceptible to space charge effects. In the context of LArTPCs, the space charge effect is the build-up of slow-moving positive ions in the detector primarily due to ionization from cosmic rays, leading to a distortion of the electric field within the detector. This effect leads to a displacement in the reconstructed position of signal ionization electrons in LArTPC detectors ("spatial distortions"), as well as to variations in the amount of electron-ion recombination experienced by ionization throughout the volume of the TPC. We present techniques that can be used to measure and correct for space charge effects in large LArTPCs by making use of cosmic muons, including the use of track pairs to unambiguously pin down spatial distortions in three dimensions. The performance of these calibration techniques are studied using both Monte Carlo simulation and MicroBooNE data, utilizing a UV laser system as a means to estimate the systematic bias associated with the calibration methodology., Comment: 38 pages, 25 figures

Published
2020
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40. First Measurement of Differential Charged Current Quasielastic-like $\nu_\mu$-Argon Scattering Cross Sections with the MicroBooNE Detector

Author

Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Rodrigues, O. Benevides, Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Cohen, E. O., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diurba, R., Domine, L., Dorrill, R., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, L., Gu, W., Guenette, R., Guzowski, P., Hall, E., Hamilton, P., Hen, O., Horton-Smith, G. A., Hourlier, A., Huang, E. -C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. -J., Kamp, N., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Littlejohn, B. R., Lorca, D., Louis, W. C., Luo, X., Marchionni, A., Marcocci, S., Marsden, C. Mariani D., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mogan, A., Mohayai, T., Moon, J., Mooney, M., Moor, A. F., Moore, C. D., Mousseau, J., Murphy, M., Naples, D., Navrer-Agasson, A., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I. D., Porzio, D., Prince, S., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Reggiani-Guzzo, M., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Rosenberg, M., Ross-Lonergan, M., Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thornton, R. T., Thorpe, C., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., Weber, M., Wei, H., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology, Nuclear Experiment, Nuclear Theory
Abstract

We report on the first measurement of flux-integrated single differential cross sections for charged-current (CC) muon neutrino ($\nu_\mu$) scattering on argon with a muon and a proton in the final state, $^{40}$Ar($\nu_\mu$,$\mu$p)X. The measurement was carried out using the Booster Neutrino Beam at Fermi National Accelerator Laboratory and the MicroBooNE liquid argon time projection chamber detector with an exposure of 4.59 $\times$ 10$^{19}$ protons on target. Events are selected to enhance the contribution of CC quasielastic (CCQE) interactions. The data are reported in terms of a total cross section as well as single differential cross sections in final state muon and proton kinematics. We measure the integrated per-nucleus CCQE-like cross section (i.e. for interactions leading to a muon, one proton and no pions above detection threshold) of (4.93 $\pm$ 0.76stat $\pm$ 1.29sys) $\times$ 10$^{-38}$cm$^2$, in good agreement with theoretical calculations. The single differential cross sections are also in overall good agreement with theoretical predictions, except at very forward muon scattering angles that correspond to low momentum-transfer events., Comment: Accepted for publication in PRL. 8 pages, 3 figures, 1 table and online supplementary materials

Published
2020
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41. Vertex-Finding and Reconstruction of Contained Two-track Neutrino Events in the MicroBooNE Detector

Author

MicroBooNE collaboration, Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bathe-Peters, L., Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Cohen, E. O., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Domine, L., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Aguirre, G. A. Fiorentini, Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Genty, V., Goeldi, D., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, L., Gu, W., Guenette, R., Guzowski, P., Hall, E., Hamilton, P., Hen, O., Hill, C., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Jwa, Y. J., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, K., Li, Y., Lister, A., Littlejohn, B. R., Lockwitz, S., Lorca, D., Louis, W. C., Luethi, M., Lundberg, B., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moore, C. D., Mousseau, J., Murphy, M., Naples, D., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Pandey, V., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Ponce-Pinto, I., Porzio, D., Prince, S., Pulliam, G., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Ren, L., Rochester, L., Rondon, J. Rodriguez, Rogers, H. E., Ross-Lonergan, M., von Rohr, C. Rudolf, Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thornton, R. T., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., Weber, M., Wei, H., Wickremasinghe, D. A., Williams, Z., Wolbers, S., Wongjirad, T., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

We describe algorithms developed to isolate and accurately reconstruct two-track events that are contained within the MicroBooNE detector. This method is optimized to reconstruct two tracks of lengths longer than 5 cm. This code has applications to searches for neutrino oscillations and measurements of cross sections using quasi-elastic-like charged current events. The algorithms we discuss will be applicable to all detectors running in Fermilab's Short Baseline Neutrino program (SBN), and to any future liquid argon time projection chamber (LArTPC) experiment with beam energies ~1 GeV. The algorithms are publicly available on a GITHUB repository. This reconstruction offers a complementary and independent alternative to the Pandora reconstruction package currently in use in LArTPC experiments, and provides similar reconstruction performance for two-track events., Comment: 35 pages, 26 figures

Published
2020
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42. The relationship between serum 25-hydroxyvitamin D and iron status and anaemia in undernourished and non-undernourished children under five years in South Africa

Author

Janet Adede Carboo, Robin Claire Dolman-Macleod, Mary A. Uyoga, Arista Nienaber, Martani Johanni Lombard, and Linda Malan

Subjects
Anaemia, Iron deficiency anaemia, Vitamin D, Vitamin D supplementation, Undernourished children, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Background: Vitamin D (vitD) plays a role in iron metabolism by the suppression of hepcidin, while iron deficiency also impairs vitD metabolism. In undernourished children, iron and vitamin D deficiency are common. There is little knowledge of the inter-relationship between these two nutrients in undernourished and non-undernourished children. Aim: To assess the association between 25-hydroxyvitamin D (25(OH)D) and iron status, and the effect of 3 doses of 50,000 IU of vitD on iron status in undernourished and non-undernourished children. Methods: We measured serum 25(OH)D, haemoglobin (Hb), ferritin and soluble transferrin receptor in 121 undernourished and 51 non-undernourished children in clinics in the North-West Province of South Africa. Three doses of 50,000 IU/week of vitD was supplemented to children with suboptimal vitD levels. Results: The overall prevalence of suboptimal vitD concentration (25(OH)D

Published
2023
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43. Race in health research: Considerations for researchers and research ethics committees

Author

W Van Staden, A Nienaber, T Rossouw, A Turner, C Filmalter, A E Mercier, J G Nel, B Bapela, M M Beetge, R Blumenthal, C D V Castelyn, T W de Witt, A G Dlagnekova, C Kotze, J S Mangwane, L Napoles, R Sommers, L Sykes, W B van Zyl, M Venter, A Uys, and N Warren

Subjects
Medical legislation, K3601-3611, Medicine, Medical philosophy. Medical ethics, R723-726
Abstract

This article provides ethical guidance on using race in health research as a variable or in defining the study population. To this end, a plain, non-exhaustive checklist is provided for researchers and research ethics committees, preceded by a brief introduction on the need for justification when using race as a variable or in defining a study population, the problem of exoticism, that distinctions pertain between race, ethnicity and ancestry, the problematic naming of races, and that race does not serve well as a presumed biological construct in genetic research.

Published
2023
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44. 'Crossing borders, connecting cultures': an introduction to the special issue

Author

Birte Nienaber, Nicole Holzapfel-Mantin, and Gabriele Budach

Subjects
Social Sciences, Communities. Classes. Races, HT51-1595, Urban groups. The city. Urban sociology, HT101-395, City population. Including children in cities, immigration, HT201-221
Abstract

Abstract This special issue of Comparative Migration Studies on the occasion of the IMISCOE 2021 Conference with the theme “Crossing borders, connecting cultures” features five invited contributions by several conference speakers as well as an article by the host university.

Published
2023
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46. Associations between soil-transmitted helminth infections and physical activity, physical fitness, and cardiovascular disease risk in primary schoolchildren from Gqeberha, South Africa.

Author

Siphesihle Nqweniso, Cheryl Walter, Rosa du Randt, Larissa Adams, Johanna Beckmann, Jean T Coulibaly, Danielle Dolley, Nandi Joubert, Kurt Z Long, Ivan Müller, Madeleine Nienaber, Uwe Pühse, Harald Seelig, Peter Steinmann, Jürg Utzinger, Markus Gerber, and Christin Lang

Subjects
Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270
Abstract

Background/aimSchool-aged children in low- and middle-income countries carry the highest burden of intestinal helminth infections, such as soil-transmitted helminths (STH). STH infections have been associated with negative consequences for child physical and cognitive development and wellbeing. With the epidemiological transition and rise in cardiovascular disease (CVD), studies have shown that helminth infections may influence glucose metabolism by preventing obesity. Thus, the aim of this study was to determine the association of STH infections in schoolchildren from Gqeberha, focusing on physical activity, physical fitness, and clustered CVD risk score.MethodsThis cross-sectional study involved 680 schoolchildren (356 girls and 324 boys; mean age 8.19 years, SD±1.4) from disadvantaged communities in Gqeberha (formerly, Port Elizabeth), South Africa. Stool samples were collected and examined for STH infections using the Kato-Katz method. Physical activity (accelerometer) and physical fitness (grip strength, 20 m shuttle run) were measured using standard procedures. Furthermore, anthropometry, blood pressure, as well as glycated haemoglobin and lipid profile from capillary blood samples were assessed. We employed one-way ANOVAs to identify the associations of STH infections in terms of species and infection intensity with physical activity, physical fitness, and clustered CVD risk score.ResultsWe found a low STH infection prevalence (7.2%) in our study, with participants infected with at least one intestinal helminth species. In comparison to their non-infected peers, children infected with STH had lower mean grip strength scores, but higher mean VO2max estimation and higher levels of MVPA (p < .001). When considering type and intensity of infection, a positive association of A. lumbricoides infection and MVPA was found. In contrast, light T. trichiura-infected children had significantly lower grip strength scores compared to non and heavily-infected children. VO2max and MVPA were positively associated with light T. trichiura infection. No significant association between the clustered CVD risk score and infection with any STH species was evident.ConclusionsSTH-infected children had lower grip strength scores than their non-infected peers, yet, achieved higher VO2max and MVPA scores. Our study highlights that the type and intensity of STH infection is relevant in understanding the disease burden of STH infections on children's health. The findings of our study must be interpreted cautiously due to the low infection rate, and more research is needed in samples with higher prevalence rates or case-control designs.

Published
2023
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47. Association of accelerometry-based and self-reported physical activity with cardiovascular risk in South African children

Author

Patricia Arnaiz, Felix Guntlisbergen, Denis Infanger, Markus Gerber, Larissa Adams, Danielle Dolley, Nandi Joubert, Madeleine Nienaber, Siphesihle Nqweniso, Rosa du Randt, Peter Steinmann, Jürg Utzinger, Cheryl Walter, Uwe Pühse, and Ivan Müller

Subjects
physical activity, accelerometry, self-report, cardiovascular health, children, South Africa, Science, Science (General), Q1-390, Social Sciences, Social sciences (General), H1-99
Abstract

The burden of non-communicable diseases is increasing, with risk factors emerging early in life. Physical activity reduces cardiovascular risk, but limited evidence exists for children from lower-income countries and mostly relies on self-reported methods that might be inaccurate and biased. We aimed to compare self-reported and accelerometer-measured physical activity in relation to cardiovascular risk markers in children from underserved communities in South Africa. We analysed cross-sectional data from 594 children aged 8 to 13. Physical activity was measured via accelerometry and the Physical Activity Questionnaire for Older Children (PAQ-C). Correlation analyses and linear regression models examined the relationship between accelerometer-measured and self-reported physical activity and their association with cardiovascular risk markers (body mass index, blood pressure, blood lipid profile and glycated haemoglobin). Results show a positive but weak correlation between PAQ-C scores and accelerometer-measured moderate-to-vigorous physical activity (MVPA). MVPA was inversely associated with body mass index, whilst sedentary behaviour correlated positively with lipid levels. PAQ-C scores were inversely associated with systolic blood pressure. The comparison of self-reported and accelerometer-measured physical activity in children from Gqeberha, South Africa, revealed inconsistencies in their correlation and association with cardiovascular risk markers. Accelerometry provided a more accurate cardiovascular risk estimation than PAQ-C, although associations were weak. Further, longitudinal studies should investigate the predictive power of both methodologies. These findings inform researchers and public health practitioners in the choice of method for physical activity appraisal beyond practical considerations, especially when combined with cardiovascular risk and in lower-income settings. Significance: We explore two widely used methods to assess physical activity levels in children. By comparing both methods, we expose inconsistencies in their correlation and association with cardiovascular risk markers. These data can guide researchers and public health practitioners in the use of one method beyond practical considerations. Whilst this work focuses on children from marginalised areas of South Africa, the issues explored are of relevance to other lower-income settings. Open data set: https://doi.org/10.5281/zenodo.7217145

Published
2023
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48. Search for heavy neutral leptons decaying into muon-pion pairs in the MicroBooNE detector

Author

Abratenko, P., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Cohen, E. O., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadón, J. I., Del Tutto, M., Devitt, D., Domine, L., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Genty, V., Goeldi, D., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Gu, L., Gu, W., Guenette, R., Guzowski, P., Hamilton, P., Hen, O., Hill, C., Horton-Smith, G. A., Hourlier, A., Huang, E. -C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Joshi, J., Jwa, Y. -J., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., LaZur, R., Lepetic, I., Li, Y., Lister, A., Littlejohn, B. R., Lockwitz, S., Lorca, D., Louis, W. C., Luethi, M., Lundberg, B., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mogan, A., Mohayai, T., Moon, J., Mooney, M., Moore, C. D., Mousseau, J., Murrells, R., Naples, D., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Pandey, V., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Porzio, D., Prince, S., Pulliam, G., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Ren, L., Rochester, L., Rogers, H. E., Ross-Lonergan, M., von Rohr, C. Rudolf, Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Söldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thornton, R. T., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., Weber, M., Wei, H., Wickremasinghe, D. A., Williams, Z., Wolbers, S., Wongjirad, T., Woodruff, K., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

We present upper limits on the production of heavy neutral leptons (HNLs) decaying to $\mu \pi$ pairs using data collected with the MicroBooNE liquid-argon time projection chamber (TPC) operating at Fermilab. This search is the first of its kind performed in a liquid-argon TPC. We use data collected in 2017 and 2018 corresponding to an exposure of $2.0 \times 10^{20}$ protons on target from the Fermilab Booster Neutrino Beam, which produces mainly muon neutrinos with an average energy of $\approx 800$ MeV. HNLs with higher mass are expected to have a longer time-of-flight to the liquid-argon TPC than Standard Model neutrinos. The data are therefore recorded with a dedicated trigger configured to detect HNL decays that occur after the neutrino spill reaches the detector. We set upper limits at the $90\%$ confidence level on the element $\lvert U_{\mu4}\rvert^2$ of the extended PMNS mixing matrix in the range $\lvert U_{\mu4}\rvert^2<(6.6$-$0.9)\times 10^{-7}$ for Dirac HNLs and $\lvert U_{\mu4}\rvert^2<(4.7$-$0.7)\times 10^{-7}$ for Majorana HNLs, assuming HNL masses between $260$ and $385$ MeV and $\lvert U_{e 4}\rvert^2 = \lvert U_{\tau 4}\rvert^2 = 0$., Comment: 11 pages, 9 figures. Final accepted version by Phys. Rev. D, minor textual changes

Published
2019
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49. Reconstruction and Measurement of $\mathcal{O}$(100) MeV Energy Electromagnetic Activity from $\pi^0 \rightarrow \gamma\gamma$ Decays in the MicroBooNE LArTPC

Author

MicroBooNE collaboration, Adams, C., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bass, M., Bay, F., Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Carr, R., Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Cohen, E. O., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diaz, A., Domine, L., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Esquivel, J., Evans, J. J., Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Genty, V., Goeldi, D., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Grosso, R., Gu, L., Gu, W., Guenette, R., Guzowski, P., Hamilton, P., Hen, O., Hill, C., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Joshi, J., Jwa, Y. J., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., Lepetic, I., Li, Y., Lister, A., Littlejohn, B. R., Lockwitz, S., Lorca, D., Louis, W. C., Luethi, M., Lundberg, B., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moore, C. D., Mousseau, J., Murphy, M., Murrells, R., Naples, D., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Pandey, V., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Porzio, D., Prince, S., Pulliam, G., Qian, X., Raaf, J. L., Rafique, A., Ren, L., Rochester, L., Rogers, H. E., Ross-Lonergan, M., von Rohr, C. Rudolf, Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thornton, R. T., Toups, M., Tsai, Y. -T., Tufanli, S., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., Weber, M., Wei, H., Wickremasinghe, D. A., Williams, Z., Wolbers, S., Wongjirad, T., Woodruff, K., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

We present results on the reconstruction of electromagnetic (EM) activity from photons produced in charged current $\nu_{\mu}$ interactions with final state $\pi^0$s. We employ a fully-automated reconstruction chain capable of identifying EM showers of $\mathcal{O}$(100) MeV energy, relying on a combination of traditional reconstruction techniques together with novel machine-learning approaches. These studies demonstrate good energy resolution, and good agreement between data and simulation, relying on the reconstructed invariant $\pi^0$ mass and other photon distributions for validation. The reconstruction techniques developed are applied to a selection of $\nu_{\mu} + {\rm Ar} \rightarrow \mu + \pi^0 + X$ candidate events to demonstrate the potential for calorimetric separation of photons from electrons and reconstruction of $\pi^0$ kinematics.

Published
2019
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50. A Method to Determine the Electric Field of Liquid Argon Time Projection Chambers Using a UV Laser System and its Application in MicroBooNE

Author

MicroBooNE collaboration, Adams, C., Alrashed, M., An, R., Anthony, J., Asaadi, J., Ashkenazi, A., Balasubramanian, S., Baller, B., Barnes, C., Barr, G., Basque, V., Bass, M., Bay, F., Berkman, S., Bhanderi, A., Bhat, A., Bishai, M., Blake, A., Bolton, T., Camilleri, L., Caratelli, D., Terrazas, I. Caro, Carr, R., Fernandez, R. Castillo, Cavanna, F., Cerati, G., Chen, Y., Church, E., Cianci, D., Cohen, E. O., Conrad, J. M., Convery, M., Cooper-Troendle, L., Crespo-Anadon, J. I., Del Tutto, M., Devitt, D., Diaz, A., Domine, L., Duffy, K., Dytman, S., Eberly, B., Ereditato, A., Sanchez, L. Escudero, Evans, J. J., Fitzpatrick, R. S., Fleming, B. T., Foppiani, N., Franco, D., Furmanski, A. P., Garcia-Gamez, D., Gardiner, S., Genty, V., Goeldi, D., Gollapinni, S., Goodwin, O., Gramellini, E., Green, P., Greenlee, H., Grosso, R., Gu, L., Gu, W., Guenette, R., Guzowski, P., Hamilton, P., Hen, O., Hill, C., Horton-Smith, G. A., Hourlier, A., Huang, E. C., Itay, R., James, C., de Vries, J. Jan, Ji, X., Jiang, L., Jo, J. H., Johnson, R. A., Joshi, J., Jwa, Y. J., Karagiorgi, G., Ketchum, W., Kirby, B., Kirby, M., Kobilarcik, T., Kreslo, I., Lepetic, I., Li, Y., Lister, A., Littlejohn, B. R., Lockwitz, S., Lorca, D., Louis, W. C., Luethi, M., Lundberg, B., Luo, X., Marchionni, A., Marcocci, S., Mariani, C., Marshall, J., Martin-Albo, J., Caicedo, D. A. Martinez, Mason, K., Mastbaum, A., McConkey, N., Meddage, V., Mettler, T., Miller, K., Mills, J., Mistry, K., Mohayai, T., Mogan, A., Moon, J., Mooney, M., Moore, C. D., Mousseau, J., Murphy, M., Murrells, R., Naples, D., Neely, R. K., Nienaber, P., Nowak, J., Palamara, O., Pandey, V., Paolone, V., Papadopoulou, A., Papavassiliou, V., Pate, S. F., Paudel, A., Pavlovic, Z., Piasetzky, E., Porzio, D., Prince, S., Pulliam, G., Qian, X., Raaf, J. L., Radeka, V., Rafique, A., Ren, L., Rochester, L., Rogers, H. E., Ross-Lonergan, M., von Rohr, C. Rudolf, Russell, B., Scanavini, G., Schmitz, D. W., Schukraft, A., Seligman, W., Shaevitz, M. H., Sharankova, R., Sinclair, J., Smith, A., Snider, E. L., Soderberg, M., Soldner-Rembold, S., Soleti, S. R., Spentzouris, P., Spitz, J., Stancari, M., John, J. St., Strauss, T., Sutton, K., Sword-Fehlberg, S., Szelc, A. M., Tagg, N., Tang, W., Terao, K., Thornton, R. T., Toups, M., Tsai, Y. -T., Tufanli, S., Uchida, M. A., Usher, T., Van De Pontseele, W., Van de Water, R. G., Viren, B., Weber, M., Wei, H., Wickremasinghe, D. A., Williams, Z., Wolbers, S., Wongjirad, T., Woodruff, K., Wospakrik, M., Wu, W., Yang, T., Yarbrough, G., Yates, L. E., Zeller, G. P., Zennamo, J., and Zhang, C.

Subjects
Physics - Instrumentation and Detectors
Abstract

Liquid argon time projection chambers (LArTPCs) are now a standard detector technology for making accelerator neutrino measurements, due to their high material density, precise tracking, and calorimetric capabilities. An electric field (E-field) is required in such detectors to drift ionized electrons to the anode to be collected. The E-field of a TPC is often approximated to be uniform between the anode and the cathode planes. However, significant distortions can appear from effects such as mechanical deformations, electrode failures, or the accumulation of space charge generated by cosmic rays. The latter is particularly relevant for detectors placed near the Earth's surface and with large drift distances and long drift time. To determine the E-field in situ, an ultraviolet (UV) laser system is installed in the MicroBooNE experiment at Fermi National Accelerator Laboratory. The purpose of this system is to provide precise measurements of the E-field, and to make it possible to correct for 3D spatial distortions due to E-field non-uniformities. Here we describe the methodology developed for deriving spatial distortions, the drift velocity and the E-field from UV-laser measurements.

Published
2019
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