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Support and management of second-intention wound healing involves frequent dressing changes having different properties. Dressings can range from simple ones, such as nonadherent dressings, to more complex options, such as foam, hydrocolloid, alginate or negative pressure dressings. Seven cats were enrolled in the study with a total of nine wounds of various sizes with different etiology sizes and localizations. Three methods of local ozone administration were used to cover more of the ozone properties in the treatment of wounds: bagging, perilesional subcutaneous infiltrations and lavages with ozonated saline. Evaluation of the healing process was performed by clinical observation and wound area measurements every seven days until the complete recovery of the patients. The results of this study should encourage clinicians to consider medical ozone as a new therapeutic approach with regenerative properties in the second-intention healing of cats presenting cutaneous wounds.

This case report describes a new therapeutic approach for a domestic shorthaired female cat, who has an extensive posttraumatic wound in the right hind limb. After patient stabilization, general anesthesia was started and the wound was cleaned and debrided of devitalized tissues, followed by the application of ozone therapy and bandage. Eight sessions of ozone therapy were performed for 17 days until the application of the skin graft. Three more sessions of ozone therapy were performed every 3 days postoperatively. The bagging method and the perilesional infiltration method were used. The ozone therapy ensured an accelerated recovery of the patient without any complications. According to our knowledge, this is the first case report with the use of ozone therapy to support a free skin graft in a cat. The new therapeutic approach could be used to accelerate healing of the wounds with a significant lack of substance, by supporting pre- and post-operative skin grafts.

Inserting orthopedic screws into a hole that is too small can produce excessive mechanical forces that cause osteocyte death and difficulty carrying out bone repair processes. The aim of the study was to evaluate the osseointegration of titanium screws 6 weeks after their insertion into the femur of male rabbits, in any smaller than the screw core. The study was conducted on 5 male rabbits aged 1 year with orthopedic titanium screws with a length of 5 mm, a diameter of 2 mm and a diameter of a screw core of 1.5 mm. The screws were inserted into the diaphysis of the femoral bone, into the hole with a diameter of 1 mm. After 6 weeks of insertion of the screws, the presence of newly proliferated tissues is found throughout the interface, but with differences from one area to another. In conclusion, the insertion of titanium screws into the hole with a diameter smaller than the screw core is accompanied by good bone proliferation in the periosteal and endosteal areas of the interface and is exceptionally modest on the portion next to the diaphyseal bone wall.