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10 results on '"Nicosia, Samanta"'

5. Lymphadenectomy for lung carcinoids: Which factors may predict nodal upstaging? A multi centric, retrospective study

Author

Chiappetta, Marco, Lococo, Filippo, Sperduti, Isabella, Cusumano, Giacomo, Terminella, Alberto, Fournel, Ludovic, Guerrera, Francesco, Filosso, Pierluigi, Tabacco, Diomira, Nicosia, Samanta, Alifano, Marco, Gallina, Filippo, Facciolo, Francesco, Margaritora, Stefano, Lococo, Filippo (ORCID:0000-0002-9383-5554), Margaritora, Stefano (ORCID:0000-0002-9796-760X), Chiappetta, Marco, Lococo, Filippo, Sperduti, Isabella, Cusumano, Giacomo, Terminella, Alberto, Fournel, Ludovic, Guerrera, Francesco, Filosso, Pierluigi, Tabacco, Diomira, Nicosia, Samanta, Alifano, Marco, Gallina, Filippo, Facciolo, Francesco, Margaritora, Stefano, Lococo, Filippo (ORCID:0000-0002-9383-5554), and Margaritora, Stefano (ORCID:0000-0002-9796-760X)

Abstract

Objective To investigate risk factors for nodal upstaging in patients with lung carcinoids and to understand which type of lymphadenectomy is most appropriate. Methods Data regarding patients with lung carcinoids, who underwent surgical resection and lymphadenectomy in five institutions from January 1, 2005 to December 31, 2019, were collected and retrospectively analyzed. Clinical and pathological tumor characteristics were correlated to analyze lymph node upstaging. Results The analysis was conducted on 283 patients. Pathology showed 230 typical and 53 atypical carcinoids. Nodal and mediastinal upstaging occurred in 33 (11.6%) and 16 (5.6%) patients, respectively. At the univariable analysis, nodal upstaging was significantly correlated with central location (p = 0.003), atypical histology (p < 0.001), pT dimension (p = 0.004), and advanced age (p = 0.043). The multivariable analysis confirmed atypical histology (odds ratio [OR]: 11.030; 95% confidence interval [CI]: 4.837-25.153, p < 0.001) and central location (OR: 3.295; 95% CI: 1.440-7.540, p = 0.005) as independent prognostic factors for nodal upstaging. Atypical histology (p < 0.001), pT dimension (p = 0.036), number of harvested lymph node stations (p = 0.047), and type of lymphadenectomy (p < 0.001) correlated significantly with mediastinal upstaging. The multivariable analysis confirmed atypical histology (OR: 5.408; 95% CI: 1.391-21.020, p = 0.015) and pT (OR: 1.052; 95% CI: 1.021-1.084, p = 0.001) as independent prognostic factors. Conclusion Atypical histology, dimension, and central location are associated with a high-risk for occult hilo-mediastinal metastases, and mediastinal radical dissection may predict nodal upstaging. Thus, we suggest radical mediastinal lymph node dissection in high-risk tumors, reserving sampling, or lobe-specific dissection in peripheral, small typical carcinoids.

Published
2022

6. External Validation of a Prognostic Score for Survival in Lung Carcinoids

Author

Chiappetta, Marco, primary, Tabacco, Diomira, additional, Sassorossi, Carolina, additional, Sperduti, Isabella, additional, Cusumano, Giacomo, additional, Terminella, Alberto, additional, Fournel, Ludovic, additional, Alifano, Marco, additional, Guerrera, Francesco, additional, Filosso, Pier Luigi, additional, Nicosia, Samanta, additional, Gallina, Filippo, additional, Facciolo, Francesco, additional, Margaritora, Stefano, additional, and Lococo, Filippo, additional

Published
2022
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7. Lymphadenectomy for lung carcinoids: Which factors may predict nodal upstaging? A multi centric, retrospective study

Author

Chiappetta, Marco, primary, Lococo, Filippo, additional, Sperduti, Isabella, additional, Cusumano, Giacomo, additional, Terminella, Alberto, additional, Fournel, Ludovic, additional, Guerrera, Francesco, additional, Filosso, PierLuigi, additional, Tabacco, Diomira, additional, Nicosia, Samanta, additional, Alifano, Marco, additional, Gallina, Filippo, additional, Facciolo, Francesco, additional, and Margaritora, Stefano, additional

Published
2022
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8. link_video – Supplemental material for Proctor-guided virtual reality–enhanced three-dimensional video-assisted thoracic surgery: an excellent tutoring model for lung segmentectomy

Author

Guerrera, Francesco, Nicosia, Samanta, Costardi, Lorena, Lyberis, Paraskevas, Femia, Federico, Filosso, Pier Luigi, Arezzo, Alberto, and Ruffini, Enrico

Subjects
Medicine
Abstract

Supplemental material, link_video for Proctor-guided virtual reality–enhanced three-dimensional video-assisted thoracic surgery: an excellent tutoring model for lung segmentectomy by Francesco Guerrera, Samanta Nicosia, Lorena Costardi, Paraskevas Lyberis, Federico Femia, Pier Luigi Filosso, Alberto Arezzo and Enrico Ruffini in Tumori Journal

Published
2020
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10. Proctor-guided virtual reality–enhanced three-dimensional video-assisted thoracic surgery: an excellent tutoring model for lung segmentectomy

Author

Guerrera, Francesco, Nicosia, Samanta, Costardi, Lorena, Lyberis, Paraskevas, Femia, Federico, Filosso, Pier Luigi, Arezzo, Alberto, and Ruffini, Enrico

Abstract

Objective: Lung segmentectomy using video-assisted thoracoscopic surgery (VATS) is an effective strategy to treat early-stage lung cancer. The objective of this case report is to show the efficacy of Hyper Accuracy 3D™ (HA3D) reconstruction as a tool for trainee surgeons and expert surgeons to perform complex procedures.Methods: An 84-year-old man was treated for colon-rectal cancer. During follow-up, a pulmonary nodule on the right anterior upper lobe suspected for intestinal metastasis was revealed by a computed tomography scan. According to functional tests and radiology, a right anterior upper lobe segmentectomy was planned. HA3D lung reconstruction was used during surgery.Results: Using the HA3D virtual model, the procedure was performed with healthy tissue sparing, ensuring safe resection margins. No postoperative morbidities were noted. The patient referred good pain control. The hospital stay was 6 days.Conclusions: VATS segmentectomy is a technically demanding procedure. HA3D lung reconstruction can help surgeons effectively perform the resection, aiding at individuating intersegmental planes, bronchi, and vessels, guaranteeing oncologic radicality and safe surgical margins, and preserving respiratory function.

Published
2021
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