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Abstract Proteins interact with each other in complex ways to perform significant biological functions. These interactions, known as protein–protein interactions (PPIs), can be depicted as a graph where proteins are nodes and their interactions are edges. The development of high-throughput experimental technologies allows for the generation of numerous data which permits increasing the sophistication of PPI models. However, despite significant progress, current PPI networks remain incomplete. Discovering missing interactions through experimental techniques can be costly, time-consuming, and challenging. Therefore, computational approaches have emerged as valuable tools for predicting missing interactions. In PPI networks, a graph is usually used to model the interactions between proteins. An edge between two proteins indicates a known interaction, while the absence of an edge means the interaction is not known or missed. However, this binary representation overlooks the reliability of known interactions when predicting new ones. To address this challenge, we propose a novel approach for link prediction in weighted protein–protein networks, where interaction weights denote confidence scores. By leveraging data from the yeast Saccharomyces cerevisiae obtained from the STRING database, we introduce a new model that combines similarity-based algorithms and aggregated confidence score weights for accurate link prediction purposes. Our model significantly improves prediction accuracy, surpassing traditional approaches in terms of Mean Absolute Error, Mean Relative Absolute Error, and Root Mean Square Error. Our proposed approach holds the potential for improved accuracy in predicting PPIs, which is crucial for better understanding the underlying biological processes.

Nowadays, the data used for decision-making come from a wide variety of sources which are difficult to manage using relational databases. To address this problem, many researchers have turned to Not only SQL (NoSQL) databases to provide scalability and flexibility for On-Line Analytical Processing (OLAP) systems. In this paper, we propose a set of formal rules to convert a multidimensional data model into a graph data model (MDM2G). These rules allow conventional star and snowflake schemas to fit into NoSQL graph databases. We apply the proposed rules to implement star-like and snowflake-like graph data warehouses. We compare their performances to similar relational ones focusing on the data model, dimensionality, and size. The experimental results show large differences between relational and graph implementations of a data warehouse. A relational implementation performs better for queries on a couple of tables, but conversely, a graph implementation is better when queries involve many tables. Surprisingly the performances of a star-like and snowflake-like graph data warehouses are very close. Hence a snowflake schema could be used in order to easily consider new sub-dimensions in a graph data warehouse.

Industry 4.0 is characterized by the availability of sensors to operate the so-called intelligent factory. Predictive maintenance, in particular, failure prediction, is an important issue to cut the costs associated with production breaks. We studied more than 40 publications on predictive maintenance. We point out that they focus on various machine learning algorithms rather than on the selection of suitable datasets. In fact, most publications consider a single, usually non-public, benchmark. More benchmarks are needed to design and test the generality of the proposed approaches. This paper is the first to define the requirements on these benchmarks. It highlights that there are only two benchmarks that can be used for supervised learning among the six publicly available ones we found in the literature. We also illustrate how such a benchmark can be used with deep learning to successfully train and evaluate a failure prediction model. We raise several perspectives for research.