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Dysregulation of the tumour suppressor gene Adenomatous Polyposis Coli (APC) is a canonical step in colorectal cancer development. Curiously, most colorectal tumours carry biallelic mutations that result in only partial loss of APC function, suggesting that a "just-right" level of APC inactivation, and hence Wnt signalling, provides the optimal conditions for tumorigenesis. Mutational processes act variably across the APC gene, which could contribute to the bias against complete APC inactivation. Thus the selective consequences of partial APC loss are unclear. Here we propose a mathematical model to quantify the tumorigenic effect of biallelic APC genotypes, controlling for somatic mutational processes. Analysing sequence data from >2500 colorectal cancers, we find that APC genotypes resulting in partial protein function confer about 50 times higher probability of progressing to cancer compared to complete APC inactivation. The optimal inactivation level varies with anatomical location and additional mutations of Wnt pathway regulators. We use this context dependency to assess the regulatory effect of secondary Wnt drivers in combination with APC in vivo, and provide evidence that mutant AMER1 combines with APC genotypes that lead to relatively low Wnt. The fitness landscape of APC inactivation is consistent across microsatellite unstable and POLE-deficient colorectal cancers and tumours in patients with Familial Adenomatous Polyposis, suggesting a general "just-right" optimum, and pointing to Wnt hyperactivation as a potential cancer vulnerability., Comment: Main: 32 pages, 7 figures Supplements: 17 pages, 7 figures

From 31 Earth-based and three Voyager 2 occultations spanning 1977--2006, we determine the orbital elements of the nine main Uranian rings with typical RMS residuals of 0.2 -- 0.4 km and 1-$\sigma$ errors in $a, ae,$ and $a\sin i$ of order 0.1 km, registered on an absolute radius scale accurate to 0.2 km at the 2-$\sigma$ level. The $\lambda$ ring shows more substantial scatter. In addition to the free modes $m=0$ in the $\gamma$ ring and $m=2$ in the $\delta$ ring, we find two additional outer Lindblad resonance (OLR) modes ($m=-1$ and $-2$) and a possible $m=3$ inner Lindblad resonance (ILR) mode in the $\gamma$ ring. No normal modes are detected for rings 6, 5, 4, $\alpha$, or $\beta$. Five normal modes are forced by small moonlets: the 3:2 inner ILR of Cressida with the $\eta$ ring, the 6:5 ILR of Ophelia with the $\gamma$ ring, the 23:22 ILR of Cordelia with the $\delta$ ring, the 14:13 ILR of Ophelia with the outer edge of the $\epsilon$ ring, and the counterpart 25:24 OLR of Cordelia with the ring's inner edge. We determine the width-radius relations for nearly all of the detected mode. We find no convincing evidence for librations of any of the rings. The Uranus pole direction at epoch TDB 1986 Jan 19 12:00 is $\alpha_P=77.311327\pm 0.000141^\circ$ and $\delta_P=15.172795\pm0.000618^\circ$. We determine the zonal gravitational coefficients $J_2=(3509.291\pm0.412)\times 10^{-6}, J_4=(-35.522\pm0.466)\times10^{-6}$, and $J_6$ fixed at $0.5\times 10^{-6}$, with a correlation coefficient $\rho(J_2,J_4)=0.9861$, for a reference radius $R=$25559 km. From the amplitudes and resonance radii of normal modes forced by moonlets, we determine the masses of Cressida, Cordelia, and Ophelia. Their estimated densities decrease systematically with increasing orbital radius and generally follow the radial trend of the Roche critical density for a shape parameter $\gamma=1.6$., Comment: 94 pages, 53 figures

Stochastic models of sequential mutation acquisition are widely used to quantify cancer and bacterial evolution. Across manifold scenarios, recurrent research questions are: how many cells are there with $n$ alterations, and how long will it take for these cells to appear. For exponentially growing populations, these questions have been tackled only in special cases so far. Here, within a multitype branching process framework, we consider a general mutational path where mutations may be advantageous, neutral or deleterious. In the biologically relevant limiting regimes of large times and small mutation rates, we derive probability distributions for the number, and arrival time, of cells with n mutations. Surprisingly, the two quantities respectively follow Mittag-Leffler and logistic distributions regardless of $n$ or the mutations' selective effects. Our results provide a rapid method to assess how altering the fundamental division, death, and mutation rates impacts the arrival time, and number, of mutant cells. We highlight consequences for mutation rate inference in fluctuation assays.

Saturn's C ring contains multiple structures that appear to be density waves driven by time-variable anomalies in the planet's gravitational field. Semi-empirical extensions of density wave theory enable the observed wave properties to be translated into information about how the pattern speeds and amplitudes of these gravitational anomalies have changed over time. Combining these theoretical tools with wavelet-based analyses of data obtained by the Visual and Infrared Mapping Spectrometer (VIMS) onboard the Cassini spacecraft reveals a suite of structures in Saturn's gravity field with azimuthal wavenumber 3, rotation rates between 804 degrees/day and 842 degrees/day and local gravitational potential amplitudes between 30 and 150 cm^2/s^2. Some of these anomalies are transient, appearing and disappearing over the course of a few Earth years, while others persist for decades. Most of these persistent patterns appear to have roughly constant pattern speeds, but there is at least one structure in the planet's gravitational field whose rotation rate steadily increased between 1970 and 2010. This gravitational field structure appears to induce two different asymmetries in the planet's gravity field, one with azimuthal wavenumber 3 that rotates at roughly 810 degrees/day and another with azimuthal wavenumber 1 rotating three times faster. The atmospheric processes responsible for generating the latter pattern may involve solar tides., Comment: 60 pages, 29 Figures, accepted for publication in the Planetary Science Journal

Saturn's rings act as a system of innumerable test particles that are remarkably sensitive to periodic disturbances in the planet's gravitational field. We identify 15 additional density and bending waves in Saturn's C ring driven by the planet's internal normal mode oscillations. Taking advantage of a highly accurate absolute radius scale for the rings, we are able to detect weak, high-wavenumber (up to m=14) waves with km-scale radial wavelengths. From a systematic scan of the entire C ring, we report the discovery and identification of 11 new Outer Lindblad Resonances (OLRs), two counterpart inner Lindblad resonances (ILRs), and two new Outer Vertical Resonances (OVRs). The close agreement of the observed resonance locations and wave rotation rates with the predictions of models of Saturn's interior suggests that all of the new waves are driven by Saturnian f-mode oscillations. As classified by their spherical harmonic shapes, the modes in question range in azimuthal wavenumber from m=8 to 14, with associated resonance orders l-m ranging from 0 to 8, where l is the overall angular wavenumber of the mode. Our suite of detections for l-m=4 is now complete from m=8 to m=14. Curiously, detections with l-m=2 are less common. These newly-identified non-sectoral waves sample latitudinal as well as radial structure within the planet and may thus provide valuable constraints on Saturn's differential rotation. Allowing for the fact that the two ILR-type waves appear to be due to the same normal modes as two of the OLR-type waves, the 13 additional modes identified here bring to 34 the number of distinct f-modes suitable for constraining interior models., Comment: Accepted for publication in Icarus

A spectral decomposition method has been implemented to identify and quantify isotopic source terms in high-resolution gamma-ray spectroscopy in static geometry and shielding scenarios. Monte-Carlo simulations were used to build the response matrix of a shielded high purity germanium detector monitoring an effluent stream with a Marinelli configuration. The decomposition technique was applied to a series of calibration spectra taken with the detector using a multi-nuclide standard. These results are compared to decay corrected values from the calibration certificate. For most nuclei in the standard ($^{241}$Am, $^{109}$Cd, $^{137}$Cs, and $^{60}$Co) the deviations from the certificate values were generally no more than $6$\% with a few outliers as high as $10$\%. For $^{57}$Co, the radionuclide with the lowest activity, the deviations from the standard reached as high as $25$\%, driven by the meager statistics in the calibration spectra. Additionally, a complete treatment of error propagation for the technique is presented., Comment: Soon to be published in: IEEE Transactions on Nuclear Science

Planet-planet scattering best explains the eccentricity distribution of extrasolar giant planets. Past literature showed that the orbits of planets evolve due to planet-planet scattering. This work studies the spin evolution of planets in planet-planet scattering in 2-planet systems. Spin can evolve dramatically due to spin-orbit coupling made possible by the evolving spin and orbital precession during the planet-planet scattering phase. The main source of torque to planet spin is the stellar torque, and the total planet-plane torque contribution is negligible. As a consequence of the evolution of the spin, planets can end up with significant obliquity (the angle between a planet's own orbit normal and spin axis) like planets in our Solar System., Comment: 7 pages, 9 figures

We now know that the outer solar system is host to at least six diverse planetary ring systems, each of which is a scientifically compelling target with the potential to inform us about the evolution, history and even the internal structure of the body it adorns. These diverse ring systems represent a set of distinct local laboratories for understanding the physics and dynamics of planetary disks, with applications reaching beyond our Solar System. We highlight the current status of planetary rings science and the open questions before the community to promote continued Earth-based and spacecraft-based investigations into planetary rings. As future spacecraft missions are launched and more powerful telescopes come online in the decades to come, we urge NASA for continued support of investigations that advance our understanding of planetary rings, through research and analysis of data from existing facilities, more laboratory work and specific attention to strong rings science goals during future mission selections.

The innovative Saturn Ring Skimmer mission concept enables a wide range of investigations that address fundamental questions about Saturn and its rings, as well as giant planets and astrophysical disk systems in general. This mission would provide new insights into the dynamical processes that operate in astrophysical disk systems by observing individual particles in Saturn's rings for the first time. The Ring Skimmer would also constrain the origin, history, and fate of Saturn's rings by determining their compositional evolution and material transport rates. In addition, the Ring Skimmer would reveal how the rings, magnetosphere, and planet operate as an inter-connected system by making direct measurements of the ring's atmosphere, Saturn's inner magnetosphere and the material owing from the rings into the planet. At the same time, this mission would clarify the dynamical processes operating in the planet's visible atmosphere and deep interior by making extensive high-resolution observations of cloud features and repeated measurements of the planet's extremely dynamic gravitational field. Given the scientific potential of this basic mission concept, we advocate that it be studied in depth as a potential option for the New Frontiers program., Comment: White paper submitted to the Planetary Science and Astrobiology Decadal Survey (submission #420)

We describe the prediction, design, execution and calibration of stellar and solar occultation observations of Saturn's rings by the Visual and Infrared Mapping Spectrometer (VIMS) instrument on the Cassini spacecraft. Particular attention is paid to the technique developed for onboard acquisition of the stellar target and to the geometric and photometric calibration of the data. Examples of both stellar and solar occultation data are presented, highlighting several aspects of the data as well as the different occultation geometries encountered during Cassini's 13 year orbital tour. Complete catalogs of ring stellar and solar occultations observed by Cassini-VIMS are presented, as a guide to the standard data sets which have been delivered to the Planetary Data System's Ring Moon Systems Node., Comment: 90 Pages, 22 Figures, Accepted for Publication in Icarus

Density waves in Saturn's rings are usually tightly wrapped spiral patterns generated by resonances with either Saturn's moons or structures inside the planet. However, between the Barnard and Bessel Gaps in the Cassini Division (i.e. between 120,240 and 120,300 km from Saturn's spin axis), there are density variations that appear to form an axisymmetric density wave consisting of concentric zones of varying densities that propagate radially through the rings. Axisymmetric waves cannot be generated directly by a satellite resonance, but instead appear to be excited by interference between a nearby satellite resonance and normal mode oscillations on the inner edge of the Barnard Gap. Similar axisymmetric waves may exist just interior to other resonantly confined edges that exhibit a large number of normal modes, including the Dawes ringlet in the outer C ring and the outermost part of the B ring., Comment: 17 pages, 15 figures. Accepted for publication in MNRAS

Recent studies of stellar occultations observed by the Visual and Infrared Mapping Spectrometer (VIMS) onboard the Cassini spacecraft have demonstrated that multiple spiral wave structures in Saturn's rings are probably generated by normal-mode oscillations inside the planet. Wavelet-based analyses have been able to unambiguously determine both the number of spiral arms and the rotation rate of many of these patterns. However, there are many more planetary normal modes that should have resonances in the rings, implying that many normal modes do not have sufficiently large amplitudes to generate obvious ring waves. Fortunately, recent advances in wavelet analysis allow weaker wave signals to be uncovered by combining data from multiple occultations. These new analytical tools reveal that a pattern previously identified as a single spiral wave actually consists of two superimposed waves, one with 5 spiral arms rotating at 1593.6 degrees/day and one with 11 spiral arms rotating at 1450.5 degrees/day. Furthermore, a broad search for new waves revealed four previously unknown wave patterns with 6, 7, 8 and 9 spiral arms rotating around the planet at 1538.2 degrees/day, 1492.5 degrees/day, 1454.2 degrees/day and 1421.8 degrees/day, respectively. These six patterns provide precise frequencies for another six fundamental normal modes inside Saturn, yielding what is now a complete sequence of fundamental sectoral normal modes with azimuthal wavenumbers from 2 to 10. These frequencies should place strong constraints on Saturn's interior structure and rotation rate, while the relative amplitudes of these waves should help clarify how the corresponding normal modes are excited inside the planet., Comment: 18 pages, 24 figures, updated to fix some typographical errors identified in proofs

Investigating the emergence of a particular cell type is a recurring theme in models of growing cellular populations. The evolution of resistance to therapy is a classic example. Common questions are: when does the cell type first occur, and via which sequence of steps is it most likely to emerge? For growing populations, these questions can be formulated in a general framework of branching processes spreading through a graph from a root to a target vertex. Cells have a particular fitness value on each vertex and can transition along edges at specific rates. Vertices represents cell states, say \mic{genotypes }or physical locations, while possible transitions are acquiring a mutation or cell migration. We focus on the setting where cells at the root vertex have the highest fitness and transition rates are small. Simple formulas are derived for the time to reach the target vertex and for the probability that it is reached along a given path in the graph. We demonstrate our results on \mic{several scenarios relevant to the emergence of drug resistance}, including: the orderings of resistance-conferring mutations in bacteria and the impact of imperfect drug penetration in cancer., Comment: Minor corrections. Altered title

We have analyzed the complete Visual and Infrared Mapping Spectrometer (VIMS) data archive of Titan. Our objective is to build global surface cartographic products, by combining all the data gathered during the 127 targeted flybys of Titan into synthetic global maps interpolated on a grid at 32 pixels per degree (~1.4 km/pixel at the equator), in seven infrared spectral atmospheric windows. Multispectral summary images have been computed for each single VIMS cube in order to rapidly identify their scientific content and assess their quality. These summary images are made available to the community on a public website (vims.univ-nantes.fr). The global mapping work faced several challenges due to the strong absorbing and scattering effects of the atmosphere coupled to the changing observing conditions linked to the orbital tour of the Cassini mission. We determined a surface photometric function which accounts for variations in incidence, emergence and phase angles, and which is able to mitigate brightness variations linked to the viewing geometry of the flybys. The atmospheric contribution has been reduced using the subtraction of the methane absorption band wings, considered as proxies for atmospheric haze scattering. We present a new global three color composite map of band ratios (red: 1.59/1.27 {\mu}m; green: 2.03/1.27 {\mu}m; blue: 1.27/1.08 {\mu}m), which has also been empirically corrected from an airmass (the solar photon path length through the atmosphere) dependence. This map provides a detailed global color view of Titan's surface partially corrected from the atmosphere and gives a global insight of the spectral variability, with the equatorial dunes fields appearing in brownish tones, and several occurrences of bluish tones localized in areas such as Sinlap, Menvra and Selk craters. (...)

The dynamic slope scaling procedure is an approximation method successfully which solves the fixed charge network flow (FCNF) problem by iteratively linearizing the fixed cost. The parameterized dynamic slope scaling procedure adds an additional $\psi$ parameter to the procedure which can significantly improve the solution quality. Finding the optimal value of $\psi$ for a given problem is non-trivial. This paper employs multiple metaheuristic techniques, including simulated annealing, tabu search, and particle swarm optimization, to guide the search for good parameter values. In rigorous testing, we examine the search results, compare the improvement efficiencies among the techniques, and evaluate the final solution quality of the FCNF problem. The experiments show that the solution improvement is robust with respect to these metaheuristics and the complexity of FCNF problem., Comment: journal paper

We have analyzed the complete archive of the Visual and Infrared Mapping Spectrometer (VIMS) data in order to monitor and analyze the evolution of the clouds and haze coverage at both poles of Titan during the entire Cassini mission. Our objective is to give a cartographic synopsis from a VIMS perspective, to provide a global view of the seasonal evolution of Titan's atmosphere over the poles. We leave the detailed comparison with the Imaging Science Subsystem (ISS) and the Composite Infrared Spectrometer (CIRS) data sets to further studies. We have computed global hyperspectral mosaics for each of the 127 targeted flybys of Titan to produce synthetic color maps emphasizing the main atmospheric features. The north pole appears fully covered by a huge cloud as soon as the first observations in 2004 and up to the equinox in 2009 (Le Mou\'elic et al. 2012). The northern skies then became progressively clearer, after the circulation turnover in 2009, revealing the underlying lakes and seas to the optical instruments up to 2017. The reverse situation is observed over the south pole, which was mostly clear of such a high obscuring cloud during the first years of the mission, but started to develop a polar cloud in 2012. This feature grew up month after month until the end of the mission in 2017, with a poleward latitudinal extent of 75$^\circ$S in 2013 up to 58$^\circ$S in April 2017. Thanks to the spectral capabilities of VIMS, we have detected HCN spectral signatures over the north pole in almost all flybys between 2004 and 2008. These HCN signatures started then to show up over the south pole in almost all flybys between 2012 and 2017, so perfectly matching the timing and spatial extent of the northern and southern polar atmospheric features.

On day 138 of 2010, the plume of dust and gas emerging from Enceladus' South Polar Terrain passed between the Sun and the Cassini spacecraft. This solar occultation enabled Cassini's Ultraviolet Imaging Spectrograph (UVIS) and the Visual and Infrared Mapping Spectrometer (VIMS) to obtain simultaneous measurements of the plume's gas and dust components along the same lines of sight. The UVIS measurements of the plume's gas content are described in Hansen et al. (2011, GRL 38:11202) , while this paper describes the VIMS data and the information they provide about the plume's particle content. Together, the VIMS and UVIS measurements reveal that the plume material above Baghdad and Damascus sulci has a dust-to-gas mass ratio that is roughly an order of magnitude higher than the material above Alexandria and Cairo sulci. Similar trends in the plume's dust-to-gas ratio are also found in data obtained when Cassini flew through the plume in 2009, during which time the Ion and Neutral Mass Spectrometer (INMS), Radio and Plasma Wave Science instrument (RPWS) and Cosmic Dust Analyzer (CDA) instruments made in-situ measurements of the plume's gas and dust densities (Dong et al. 2015 JGR 120:915-937). These and other previously-published systematic differences in the material erupting from different fissures likely reflect variations in subsurface conditions across Encealdus' South Polar Terrain., Comment: 24 pages, 14 figures, submitted for publication in Icarus

Planet-planet scattering is the leading mechanism to explain the broad eccentricity distribution of observed giant exoplanets. Here we study the orbital stability of primordial giant planet moons in this scenario. We use N-body simulations including realistic oblateness and evolving spin evolution for the giant planets. We find that the vast majority (80-90% across all our simulations) of orbital parameter space for moons is destabilized. There is a strong radial dependence, as moons past 0.1 Hill radii are systematically removed. Closer-in moons on Galilean-moon-like orbits (< 0.04 Hill radii) have a good ( 20-40%) chance of survival. Destabilized moons may undergo a collision with the star or a planet, be ejected from the system, be captured by another planet, be ejected but still orbiting its free-floating host planet, or survive on heliocentric orbits as "planets." The survival rate of moons increases with the host planet mass but is independent of the planet's final (post-scattering) orbits. Based on our simulations we predict the existence of an abundant galactic population of free- floating (former) moons., Comment: 15 pages, 9 figures, 1 table, accepted for publication in ApJ

The viscous spreading of planetary rings is believed to be counteracted by satellite torques, either through an individual resonance or through overlapping resonances. For the A ring of Saturn, it has been commonly believed that the satellite Janus alone can prevent the ring from spreading via its 7:6 Lindblad resonance. We discuss this common misconception and show that, in reality, the A ring is confined by the contributions from the group of satellites Pan, Atlas, Prometheus, Pandora, Janus, Epimetheus, and Mimas, whose cumulative torques from various resonances gradually decrease the angular momentum flux transported outward through the ring via density and bending waves. We further argue that this decrease in angular momentum flux occurs through 'flux reversal'. Furthermore, we use the magnitude of the satellites' resonance torques to estimate the effective viscosity profile across the A ring, showing that it decreases with radius from ~50 cm2 s-1 to less than ~10 cm2 s-1. The gradual estimated decrease of the angular momentum flux and effective viscosity are roughly consistent with results obtained by balancing the shepherding torques from Pan and Daphnis with the viscous torque at the edges of the Encke and Keeler gaps, as well as the edge of the A ring. On the other hand, the Mimas 2:1 Lindblad resonance alone seems to be capable of confining the edge of the B ring, and contrary to the situation in the A ring, we show that the effective viscosity across the B ring is relatively constant at ~24-30 cm2 s-1., Comment: 38 pages, 3 figures

We analyze several thousand Cassini ISS images in order to study the inner edge of the Keeler gap in Saturn's outer A ring. We find strong evidence for an m=32 perturbation with a mean amplitude of radial variation of 4.5 km. Phase analysis yields a pattern speed consistent with the mean motion of Prometheus, indicating that this pattern is generated by the 32:31 Inner Lindblad resonance with Prometheus. In addition, we find evidence of 18-lobed and 20-lobed patterns with amplitudes of ~1.5 km. These patterns, whose rotation rates correspond to resonance locations ~4 km interior to the gap edge, are believed to be normal modes. The former is probably related to the nearby 18:17 (m=18) resonance with Pandora. In addition to these resonant and normal mode patterns, we also observe multiple localized features that appear to move at the local keplerian rate and that persist for only a few months. One hypothesis is that different groups of ring particles at the inner edge of the gap may be reacting differently to the resonance with Prometheus, with local variations in the forced eccentricity and/or pericenter; an alternative hypothesis is the existence of several unseen objects embedded at or near the inner edge of the Keeler gap, similar to those suspected to exist at the outer edges of the A and B rings (Spitale and Porco 2009, 2010). In either case, observations of the ring edge at opposite ansae demonstrate that the localized features must be on eccentric orbits.

The construction of the KAT-7 array in the Karoo region of the Northern Cape in South Africa was intended primarily as an engineering prototype for technologies and techniques applicable to the MeerKAT telescope. This paper looks at the main engineering and scien- tific highlights from this effort, and discusses their applicability to both MeerKAT and other next-generation radio telescopes. In particular we found that the composite dish surface works well, but it becomes complicated to fabricate for a dish lacking circular symmetry; the Stir- ling cycle cryogenic system with ion pump to achieve vacuum works but demands much higher maintenance than an equivalent Gifford-McMahon cycle system; the ROACH (Recon- figurable Open Architecture Computing Hardware)-based correlator with SPEAD (Stream- ing Protocol for Exchanging Astronomical Data) protocol data transfer works very well and KATCP (Karoo Array Telescope Control Protocol) control protocol has proven very flexible and convenient. KAT-7 has also been used for scientific observations where it has a niche in mapping low surface-brightness continuum sources, some extended HI halos and OH masers in star-forming regions. It can also be used to monitor continuum source variability, observe pulsars, and make VLBI observations

Deterministically growing (wild-type) populations which seed stochastically developing mutant clones have found an expanding number of applications from microbial populations to cancer. The special case of exponential wild-type population growth, usually termed the Luria-Delbr\"uck or Lea-Coulson model, is often assumed but seldom realistic. In this article we generalise this model to different types of wild-type population growth, with mutants evolving as a birth-death branching process. Our focus is on the size distribution of clones - that is the number of progeny of a founder mutant - which can be mapped to the total number of mutants. Exact expressions are derived for exponential, power-law and logistic population growth. Additionally for a large class of population growth we prove that the long time limit of the clone size distribution has a general two-parameter form, whose tail decays as a power-law. Considering metastases in cancer as the mutant clones, upon analysing a data-set of their size distribution, we indeed find that a power-law tail is more likely than an exponential one., Comment: 22 pages, 4 figures. To appear in the Bulletin of Mathematical Biology doi:10.1007/s11538-016-0221-x

The spectral position of the 3.6 micron continuum peak measured on Cassini-VIMS I/F spectra is used as a marker to infer the temperature of the regolith particles covering the surfaces of Saturn's icy satellites. This feature is characterizing the crystalline water ice spectrum which is the dominant compositional endmember of the satellites' surfaces. Laboratory measurements indicate that the position of the 3.6 micron peak of pure water ice is temperature-dependent, shifting towards shorter wavelengths when the sample is cooled, from about 3.65 micron at T=123 K to about 3.55 micron at T=88 K. A similar method was already applied to VIMS Saturn's rings mosaics to retrieve ring particles temperature (Filacchione et al., 2014). We report here about the daytime temperature variations observed on the icy satellites as derived from three different VIMS observation types. Temperature maps are built by mining the complete VIMS dataset collected in years 2004-2009 (pre-equinox) and in 2009-2012 (post equinox) by selecting pixels with max 150 km/pixel resolution. VIMS-derived temperature maps allow to identify thermal anomalies across the equatorial lens of Mimas and Tethys., Comment: 42 pages, 15 figures. Accepted for publication in Icarus journal on February 8th 2016

Saturn's B ring is the most opaque ring in our solar system, but many of its fundamental parameters, including its total mass, are not well constrained. Spiral density waves generated by mean-motion resonances with Saturn's moons provide some of the best constraints on the rings' mass density, but detecting and quantifying such waves in the B ring has been challenging because of this ring's high opacity and abundant fine-scale structure. Using a wavelet-based analyses of 17 occultations of the star gamma Crucis observed by the Visual and Infrared Mapping Spectrometer (VIMS) onboard the Cassini spacecraft, we are able to examine five density waves in the B ring. Two of these waves are generated by the Janus 2:1 and Mimas 5:2 Inner Lindblad Resonances at 96,427 km and 101,311 km from Saturn's center, respectively. Both of these waves can be detected in individual occultation profiles, but the multi-profile wavelet analysis reveals unexpected variations in the pattern speed of the Janus 2:1 wave that might arise from the periodic changes in Janus' orbit. The other three wave signatures are associated with the Janus 3:2, Enceladus 3:1 and Pandora 3:2 Inner Lindblad Resonances at 115,959 km, 115,207 km and 108,546 km. These waves are not visible in individual profiles, but structures with the correct pattern speeds can be detected in appropriately phase-corrected average wavelets. Estimates of the ring's surface mass density derived from these five waves fall between 40 and 140 g/cm^2, even though the ring's optical depth in these regions ranges from 1.5 to almost 5. This suggests that the total mass of the B ring is most likely between one-third and two-thirds the mass of Saturn's moon Mimas., Comment: 40 Pages, 21 Figures, Accepted for publication in Icarus, a few typos fixed

We present the Cassini Atlas Of Stellar Spectra (CAOSS), comprised of near-infrared low-resolution spectra of bright stars recovered from space-based observations by the Cassini spacecraft. The 65 stellar targets in the atlas are predominately M, K and S giants. However it also contains spectra of other bright nearby stars including carbon stars and main sequence stars from A to F. The spectra presented are free of all spectral contamination caused by the Earth's atmosphere, including the detrimental telluric molecular bands which put parts of the near-infrared spectrum out of reach of terrestrial observations. With a single instrument, a spectro-photometric dataset is recovered that spans the near-infrared from 0.8 to 5.1 microns with spectral resolution ranging from R=53.5 to R=325. Spectra have been calibrated into absolute flux units after careful characterisation of the instrumental spectral efficiency. Spectral energy distributions for most stars match closely with literature values. All final data products have been made available online., Comment: 10 emulateapj pages, 4 figures, 4 tables. Accepted by ApJS. Full atlas available at http://www.physics.usyd.edu.au/sifa/caoss/

High angular resolution images of IRC+10216 are presented in several near infrared wavelengths spanning more than 8 years. These maps have been reconstructed from interferometric observations obtained at both Keck and the VLT, and also from stellar occultations by the rings of Saturn observed with the Cassini spacecraft. The dynamic inner regions of the circumstellar environment are monitored over eight epochs ranging between January 2000 and July 2008. The system is shown to experience substantial evolution within this period including the fading of many previously reported persistent features, some of which had been identified as the stellar photosphere. These changes are discussed in context of existing models for the nature of the underlying star and the circumstellar environment. With access to these new images, we are able to report that none of the previously identified bright spots in fact contain the star, which is buried in its own dust and not directly visible in the near infrared., Comment: 9 pages, 6 figures, Accepted by MNRAS

We use solar occultations observed by the Visual and Infrared Mapping Spectrometer aboard the Cassini Spacecraft to extract the 1 to 5 micron transmission spectrum of Saturn, as if it were a transiting exoplanet. We detect absorption from methane, ethane, acetylene, aliphatic hydrocarbons, and possibly carbon monoxide with peak-to-peak features of up to 90 parts-per-million despite the presence of ammonia clouds. We also find that atmospheric refraction, as opposed to clouds or haze, determines the minimum altitude that could be probed during mid-transit. Self-consistent exoplanet atmosphere models show good agreement with Saturn's transmission spectrum but fail to reproduce a large absorption feature near 3.4 microns likely caused by gaseous ethane and a C-H stretching mode of an unknown aliphatic hydrocarbon. This large feature is located in one of the Spitzer Space Telescope bandpasses and could alter interpretations of transmission spectra if not properly modeled. The large signal in Saturn's transmission spectrum suggests that transmission spectroscopy of cold, long-period gaseous exoplanets should be possible with current and future observatories. Motivated by these results, we briefly consider the feasibility of a survey to search for and characterize cold exoplanets analogous to Jupiter and Saturn using a target-of-opportunity approach., Comment: 15 pages, 9 figures. Accepted to ApJ. Data available in the source files

We present a study of the behavior of Saturn's A ring outer edge, using images and occultation data obtained by the Cassini spacecraft over a period of 8 years from 2006 to 2014. More than 5000 images and 170 occultations of the A ring outer edge are analyzed. Our fits confirm the expected response to the Janus 7:6 Inner Lindblad resonance (ILR) between 2006 and 2010, when Janus was on the inner leg of its regular orbit swap with Epimetheus. During this period, the edge exhibits a regular 7-lobed pattern with an amplitude of 12.8 km and one minimum aligned with the orbital longitude of Janus, as has been found by previous investigators. However, between 2010 and 2014, the Janus/Epimetheus orbit swap moves the Janus 7:6 LR away from the A ring outer edge, and the 7-lobed pattern disappears. In addition to several smaller-amplitudes modes, indeed, we found a variety of pattern speeds with different azimuthal wave numbers, and many of them may arise from resonant cavities between the ILR and the ring edge; also we found some other signatures consistent with tesseral resonances that could be associated with inhomogeneities in Saturn's gravity field. Moreover, these signatures do not have a fixed pattern speed. We present an analysis of these data and suggest a possible dynamical model for the behavior of the A ring's outer edge after 2010.

The spatial distribution of the tropospheric methane on Titan was measured using near-infrared spectroscopy. Ground-based observations at 1.5$\mu{\rm m}$ (H-band) were performed during the same night using instruments with adaptive optics at both the W. M. Keck Observatory and at the Paranal Observatory on 17 July 2014 UT. The integral field observations with SINFONI on the VLT covered the entire H-band at moderate resolving power, $R=\lambda/\Delta\lambda\approx1,500$, while the Keck observations were performed with NIRSPAO near 1.55254$\mu{\rm m}$ at higher resolution, $R\approx25,000$. The moderate resolution observations are used for flux calibration and for the determination of model parameters that can be degenerate in the interpretation of high resolution spectra. Line-by-line calculations of CH$_4$ and CH$_3$D correlated $k$ distributions from the HITRAN 2012 database were used, which incorporate revised line assignments near 1.5$\mu{\rm m}$. We fit the surface albedo and aerosol distributions in the VLT SINFONI observations that cover the entire H-band window and used these quantities to constrain the models of the high-resolution Keck NIRSPAO spectra when retrieving the methane abundances. Cassini VIMS images of the polar regions, acquired on 20 July 2014 UT, are used to validate the assumption that the opacity of tropospheric aerosol is relatively uniform below 10 km. We retrieved methane abundances at latitudes between 42$^{\circ}$ S and 80$^{\circ}$ N. The tropospheric methane in the Southern mid-latitudes was enhanced by a factor of $\sim$10--40% over the nominal profile that was measured using the GCMS on Huygens. The Northern hemisphere had $\sim$90% of the nominal methane abundance up to polar latitudes (80$^{\circ}$N). These measurements suggest that a source of saturated polar air is equilibrating with dryer conditions at lower latitudes., Comment: Accepted for publication in Icarus on May 22, 2015

We present an advance in the use of Cassini observations of stellar occultations by the rings of Saturn for stellar studies. Stewart et al. (2013) demonstrated the potential use of such observations for measuring stellar angular diameters. Here, we use these same observations, and tomographic imaging reconstruction techniques, to produce two dimensional images of complex stellar systems. We detail the determination of the basic observational reference frame. A technique for recovering model-independent brightness profiles for data from each occulting edge is discussed, along with the tomographic combination of these profiles to build an image of the source star. Finally we demonstrate the technique with recovered images of the {\alpha} Centauri binary system and the circumstellar environment of the evolved late-type giant star, Mira., Comment: 8 pages, 8 figures, Accepted by MNRAS

This work shows the dynamical instability that can happen to close-in satellites when planet oblateness is not accounted for in non-coplanar multiplanet systems. Simulations include two secularly interacting Jupiter-mass planets mutually inclined by 10 degrees, with the host planet either oblate or spherical. With a spherical host planet, moons within a critical planetocentric distance experience high inclinations and in some cases high eccentricities, while more distant moons orbit stably with low inclinations and eccentricities, as expected. These counter-intuitive dynamical phenomena disappear with an oblate host planet, in which case the moons' Laplace plane transitions from the host planet's equatorial plane to the host planet's precessing orbital plane as their semi-major axes increase, and all moons are dynamically stable with very mild changes in orbits. Direct perturbation from the perturbing planet has been investigated and ruled out as an explanation for the behavior of the innermost satellites, therefore leaving the central star's perturbation as the cause. Instability occurs while the nodal precession of the satellite and the central star (as seen from the host planet's frame) approaches the 1:1 secular resonance. In non-coplanar systems, around a non-oblate planet, the nodal precession of the moon becomes slow and comparable to that of the planet, giving rise to resonant configurations. The above effect needs to be taken into account in setting up numerical simulations., Comment: 7 pages, 6 figures. Accepted for publication in MNRAS