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2. Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability

4. Mechanisms and pathologies of human mitochondrial DNA replication and deletion formation.

6. List of Contributors

7. Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer

8. Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

9. Two type I topoisomerases maintain DNA topology in human mitochondria

10. The human mitochondrial genome contains a second light strand promoter

11. Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion

15. The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication

19. Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

21. Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

22. Understanding mitochondrial DNA maintenance disorders at the single muscle fibre level

23. Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease

25. Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

26. Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA

29. Mutations in GTPBP3 Cause a Mitochondrial Translation Defect Associated with Hypertrophic Cardiomyopathy, Lactic Acidosis, and Encephalopathy

32. ELAC2 Mutations Cause a Mitochondrial RNA Processing Defect Associated with Hypertrophic Cardiomyopathy

34. Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

35. The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication.

36. Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion

37. Isolating Mitochondria, Mitoplasts, and mtDNA from Cultured Mammalian Cells.

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