Search

Race is a social construct that contributes to group membership and heightens emotional arousal in intergroup contexts. Little is known about how emotional arousal, specifically uncertain threat, influences behavior and brain processes in response to race information. We investigated the effects of experimentally manipulated uncertain threat on impulsive actions to Black versus White faces in a community sample (n = 106) of Black and White adults. While undergoing fMRI, participants performed an emotional go/no-go task under three conditions of uncertainty: 1) anticipation of an uncertain threat (i.e., unpredictable loud aversive sound); 2) anticipation of an uncertain reward (i.e., unpredictable receipt of money); and 3) no anticipation of an uncertain event. Representational similarity analysis was used to examine the neural representations of race information across functional brain networks between conditions of uncertainty. Participants—regardless of their own race—showed greater impulsivity and neural dissimilarity in response to Black versus White faces across all functional brain networks in conditions of uncertain threat relative to other conditions. This pattern of greater neural dissimilarity under threat was enhanced in individuals with high implicit racial bias. Our results illustrate the distinct and important influence of uncertain threat on global differentiation in how race information is represented in the brain, which may contribute to racially biased behavior.

The race of an individual is a salient physical feature that is rapidly processed by the brain and can bias our perceptions of others. How the race of others explicitly impacts our actions toward them during intergroup contexts is not well understood. In the current study, we examined how task-irrelevant race information influences cognitive control in a go/no-go task in a community sample of Black (n = 54) and White (n = 51) participants. We examined the neural correlates of behavioral effects using functional magnetic resonance imaging and explored the influence of implicit racial attitudes on brain-behavior associations. Both Black and White participants showed more cognitive control failures, as indexed by dprime, to Black versus White faces, despite the irrelevance of race to the task demands. This behavioral pattern was paralleled by greater activity to Black faces in the fusiform face area, implicated in processing face and in-group information, and lateral orbitofrontal cortex, associated with resolving stimulus-response conflict. Exploratory brain-behavior associations suggest different patterns in Black and White individuals. Black participants exhibited a negative association between fusiform activity and response time during impulsive errors to Black faces, whereas White participants showed a positive association between lateral OFC activity and cognitive control performance to Black faces when accounting for implicit racial associations. Together our findings propose that attention to race information is associated with diminished cognitive control that may be driven by different mechanisms for Black and White individuals. Supplementary Information The online version contains supplementary material available at 10.3758/s13415-021-00896-8.

[Correction Notice: An Erratum for this article was reported online in Journal of Personality and Social Psychology on May 21 2020 (see record 2020-36018-001). In the article, the phrase Mixed Effects in the table title for Tables 1-3 and Tables 6-8 is incorrect. The corrected phrase should appear instead as Fixed Effects. All versions of this article have been corrected.] In the United States, God is commonly conceptualized as the omnipotent and omniscient entity that created the universe, and as a White man. We questioned whether the extent to which God is conceptualized as a White man predicts the extent to which White men are perceived as particularly fit for leadership. We found support for this across 7 studies. In Study 1, we created 2 measures to examine the extent to which U.S. Christians conceptualized God as a White man, and in Study 2 we found that, controlling for multiple covariates (e.g., racist and sexist attitudes, religiosity, political attitudes), responses on these measures predicted perceiving White male job candidates as particularly fit for leadership, among both Black and White, male and female, Christians. In Study 3, we found that U.S. Christian children, both White and racial minority, conceptualized God as more White than Black (and more male than female), which predicted perceiving White people as particularly boss-like. We next found evidence to suggest that this phenomenon is rooted in broader intuitions that extend beyond Christianity. That is, in a novel context with novel groups and a novel god, U.S. Christian adults (Studies 4 and 6), atheist adults (Study 5), and agnostic preschoolers (Study 7), used a god's identity to infer which groups were best fit for leadership. Collectively, our data reveal a clear and consistent pattern: Attributing a social identity to God predicts perceiving individuals who share that identity as more fit for leadership. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

An asymmetric synthetic route to (-)-galanthamine (

How do routine police encounters build or undermine community trust, and how might they contribute to racial gaps in citizen perceptions of the police? Procedural justice theory posits that officers' interpersonal communication toward the public plays a formative role, but experimental tests of this hypothesis have been constrained by the difficulties of measuring and manipulating this dimension of officer-citizen interactions. Officer-worn body camera recordings provide a novel means to overcome both of these challenges. Across five studies with laboratory and community samples, we use footage from traffic stops to examine how officers communicate to drivers and whether racial disparities in officers' communication erode institutional trust in the police. Specifically, we consider the cumulative effects of one subtle interpersonal cue: an officer's tone of voice. In Studies 1A, 1B, and 1C, participants rated thin slices of officer speech. Participants were blind to the content of the officer's words and the race of their interlocutor, yet they evaluated officers' tone toward White (vs. Black) men more positively. By manipulating participants' exposure to repeated interactions, we demonstrate that even these paraverbal aspects of police interactions shape how citizens construe the police generally (Study 2), and that racial disparities in prosodic cues undermine trust in institutions such as police departments (Study 3). Participants' trust in the police, and personal experiences of fairness, in turn, correlated with their perceptions of officer prosody across studies. Taken together, these data illustrate a cycle through which interpersonal aspects of police encounters erode institutional trust across race. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Significance The tendency to view members of social outgroups as interchangeable has long been considered a core component of intergroup bias and a precursor to stereotyping and discrimination. However, the early perceptual nature of these intergroup biases is poorly understood. Here, we used a functional MRI adaptation paradigm to assess how face-selective brain regions respond to variation in physical similarity among racial ingroup (White) and outgroup (Black) faces. We conclude that differences emerge in the different tuning properties of early face-selective cortex for racial ingroup and outgroup faces and mirror behavioral differences in memory and perception of racial ingroup versus outgroup faces. These results suggest that outgroup deindividuation emerges at some of the earliest stages of perception., A hallmark of intergroup biases is the tendency to individuate members of one’s own group but process members of other groups categorically. While the consequences of these biases for stereotyping and discrimination are well-documented, their early perceptual underpinnings remain less understood. Here, we investigated the neural mechanisms of this effect by testing whether high-level visual cortex is differentially tuned in its sensitivity to variation in own-race versus other-race faces. Using a functional MRI adaptation paradigm, we measured White participants’ habituation to blocks of White and Black faces that parametrically varied in their groupwise similarity. Participants showed a greater tendency to individuate own-race faces in perception, showing both greater release from adaptation to unique identities and increased sensitivity in the adaptation response to physical difference among faces. These group differences emerge in the tuning of early face-selective cortex and mirror behavioral differences in the memory and perception of own- versus other-race faces. Our results suggest that biases for other-race faces emerge at some of the earliest stages of sensory perception.

Recent work suggests that secrecy is perceived as burdensome. A secrecy-burden relationship would have a number of consequences for cognitive, perceptual, social, and health psychology, but the reliability of these influences, and potential mechanisms that support such influences are unknown. Across 4 studies, the current work examines both the reliability of, and mechanisms that support, the influence of secrecy processes upon a judgment that varies with diminished resources (i.e., judgments of hill slant). The current work finds that a manipulation of secret "size" fails to reliably predict judged hill slant, whereas measurement and manipulation of preoccupation with a secret does reliably predict judged hill slant. Moreover, these effects are found to be mediated by judged effort to keep the secret, consistent with a resource-based mechanism of the burdens of secrecy.

Using footage from body-worn cameras, we analyze the respectfulness of police officer language toward white and black community members during routine traffic stops. We develop computational linguistic methods that extract levels of respect automatically from transcripts, informed by a thin-slicing study of participant ratings of officer utterances. We find that officers speak with consistently less respect toward black versus white community members, even after controlling for the race of the officer, the severity of the infraction, the location of the stop, and the outcome of the stop. Such disparities in common, everyday interactions between police and the communities they serve have important implications for procedural justice and the building of police-community trust.

A new and highly efficient synthesis of the potent nicotinic acetylcholine receptor agonist, anatoxin-a and its analogues is described, which uses a s-lactam ring opening-transannular cyclisation sequence to set up the bridged bicyclic framework of the natural product. The synthesis involves a cycloaddition of chlorosulfonyl isocyanate with cyclooctadiene followed by Boc protection of the resulting s-lactam. Reaction of the s- lactam with a variety of nucleophiles, followed by selenium-mediated cyclisation and oxidation gave the skeleton of anatoxin-a bearing various sidechains. The approach offers a flexible entry to useful quantities of anatoxin-a and its analogues.

The present studies are the first in which social psychological methods were used to test the popular claim that the experience of concealing a stigmatized social identity leads to a "divided self." For people with concealable stigmas, concealment in public settings makes the public-private dimension of self-expression particularly salient, leading them to organize self-relevant information along this dimension. The result is a strengthened cognitive distinction between public and private aspects of the self, what we have termed public-private schematization. We developed and tested a measure of the cognitive accessibility of the distinction between public and private self-schemas by measuring how quickly participants sorted trait attributes into self-in-public (e.g., self-at-work) and self-in-private (e.g., self-at-home). People with more accessible distinct public and private self-schemas should be faster at categorizing trait attributes into public- and private-self aspects than those with more integrated public and private self-schemas. Relative to people without such identities, people with concealable stigmas (Study 1a, sexual orientation; Study 1b, religiosity at a secular college), show greater public-private schematization. This schematization is linked to concealment (Study 2) and to the experimental activation of concealable versus conspicuous stigmatized identities (Study 3). Implications of distinct public and private self-schemas for psychological well-being are explored in Studies 4 and 5. Two different measures of distress-perceived social stress (Study 4) and depressive symptoms (Study 5)-provided evidence showing that the accessibility of the distinction between public and private self-schemas accounted for the association of concealment on heightened distress. Implications for research on concealment and self-structure are discussed.

A new route to anatoxin- a (1) is reported which involves an anionically induced small ring opening / ring closure / ring opening cascade. The azabicyclo[4.2.1]nonane ring system of anatoxin- a is hence formed in one synthetic operation.

Phosphonamidate-containing peptidic substrate analogues of the HIV-1 gag-pol proteinase-reverse transcriptase junction {-Phe-ψ[PO2-N]-(S)-Pro- and -Phe-ψ[P(OMe)O-N]-(S)-Pro-}, mimicks for the transition states for proteolysis, have been synthesised. The absolute stereochemistry at C-1 of the phosphonophenylalanine residue was determined by X-ray crystallography. Boc-(S)-Asn-Phe-ψ[PO2-N]-(S)-Ile-NH-i-Bu and Boc-(S)-Asn-(R)-Phe-ψ[P(OMe)O-N]-(S)-Pro-(S)-Ile-NH-i-Bu inhibit the HIV-1 proteinase.

An enantioselective synthesis of (-)-galanthamine has been realized in 11 linear steps starting from isovanillin. A Mitsunobu aryl ether forming reaction was used to assemble the galanthamine backbone, which was stitched together using enyne ring-closing metathesis, Heck, and N-alkylation reactions affording the tetracyclic ring system. Control of relative and absolute stereochemistry was derived from an easily accessible enantiomerically enriched propargylic alcohol 13.

A new route to Anatoxin-a1 is reported which involves a tandem methyllithium mediated ring opening/intramolecular cyclisation as a key step to provide the required 2-acetyl-9-azabicyclo [4.2.1] nonane ring structure in one synthetic operation.

Stereochemically defined and epimeric phosphonamidate methyl ester-containing peptide analogues were synthesised and were found to be moderate inhibitors of the HIV-1 proteinase. All of the analogues containing the phosphonamidate ester grouping showed a marked ability to enter cells, as highlighted by the approximate equivalence of the IC50 values for enzyme inhibition in solution and inhibition of HIV-1 replication in virus infected cells.