45 results on '"Nguyen Quynh Hoa"'
Search Results
2. Antibiotic prescribing and dispensing for acute respiratory infections in children: effectiveness of a multi-faceted intervention for health-care providers in Vietnam
- Author
-
Nguyen Quynh Hoa, Pham Thi Lan, Ho D. Phuc, Nguyen Thi Kim Chuc, and Cecilia Stalsby Lundborg
- Subjects
antibiotics ,acute respiratory tract infections ,health-care provider ,intervention ,vietnam ,Public aspects of medicine ,RA1-1270 - Abstract
Background: Appropriate antibiotic use is vital to effectively contain antibiotic resistance and improve global health. Acute respiratory infections (ARIs) remain the leading cause of disease and death in children under five in low-income countries. Objective: To evaluate a multi-faceted intervention targeting health-care-providers’ (HCPs) knowledge, practical competences and practices regarding antibiotic use for ARIs. Methods: A multi-faceted educational intervention with a two-armed randomised controlled design targeting HCPs treating ARIs in children was conducted in Bavi district, a rural district in Northern Vietnam in 2010–2011. Thirty-two communes of the district were randomized into two arms, with 144 HCPs in the intervention arm and 160 in the control arm. The intervention, conducted over seven months, comprised: (i) education regarding appropriate-antibiotic use, (ii) case scenario discussion and (iii) poster distribution. Questionnaires to assess knowledge and dispensing/prescribing forms to assess practice were completed before-and after interventions. The main outcome measures were differences in improvement in knowledge and practice in the intervention and control group, respectively. Results: Knowledge improved in the intervention group for ARI aetiology by 28% (ΔDecrement control arm 10%), antibiotic use for mild ARIs by 15% (ΔDecrement control arm 13%) and for severe ARIs by 14% (ΔImprovement control arm 29%). Practical competence for a mild ARI case scenario improved in the intervention and control groups by 20% and 11%, respectively. Total knowledge score increased statistically in the intervention group (Δmean improvement 1.17); less so in the control group (Δmean improvement 0.48). Practice regarding antibiotics for mild ARIs improved by 28% in the intervention group (ΔDecrement control arm 3%). Conclusions: The intervention significantly improved HCPs’ knowledge of ARIs and practice of antibiotic use in treatment of ARIs. We suggest mixed method assessment and long-term follow-up of these interventions to enable better appreciation of the effects and effect sizes of our interventions.
- Published
- 2017
- Full Text
- View/download PDF
3. The Impact of the ASEAN Trade in Goods Agreement (ATIGA) on Vietnam’s Pangasius Export to ASEAN Markets—A Study of Thailand, Singapore, and Philippines Markets
- Author
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Nguyen, Quynh Hoa, Ngo, Quoc Dung, Vu, Cuong, Tran, Hoa Van Thi, editor, Shioji, Hiromi, editor, Le, Huong Lan Thi, editor, and Hayashi, Takabumi, editor
- Published
- 2024
- Full Text
- View/download PDF
4. Analysis of factors affecting Ho Chi Minh city’s office rental price using Hedonic model
- Author
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Le Van Thuong, Nguyen Quynh Hoa, and Nguyen Van Toan
- Subjects
Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Research on the application of Hedonic model in analyzing factors which affect office rental price in HCM city CBD area. The author uses primary data source comprised of 146 observations collected in district 1 and district 3 during the first 6 months of 2015. By using OLS method, together with three regression models commonly used in researches on the application of Hedonic model, the result shows significant impact of factors, such as building classification, management fee, road on which the building is situated, and district location on office rental price. The result of this research can be applied in the field of real estate management, investment consulting, office rental.
- Published
- 2018
- Full Text
- View/download PDF
5. Host Residents’ Support and Perceptions Toward Major Sport Events’ Impacts on Sustainable Development Post-COVID19: Case Study of SEAGAMES 31
- Author
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Nguyen Quynh, Hoa, Chen, Chris (Ning), Pham Chi, Chi, Appolloni, Andrea, Series Editor, Caracciolo, Francesco, Series Editor, Ding, Zhuoqi, Series Editor, Gogas, Periklis, Series Editor, Huang, Gordon, Series Editor, Nartea, Gilbert, Series Editor, Ngo, Thanh, Series Editor, Striełkowski, Wadim, Series Editor, Pham, Tra Lam, editor, and Pham, Quang Huy, editor
- Published
- 2023
- Full Text
- View/download PDF
6. Host Residents’ Support and Perceptions Toward Major Sport Events’ Impacts on Sustainable Development Post-COVID19: Case Study of SEAGAMES 31
- Author
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Nguyen Quynh, Hoa, primary, Chen, Chris, additional, and Pham Chi, Chi, additional
- Published
- 2023
- Full Text
- View/download PDF
7. Examining the Predictability of Tropical Cyclogenesis over the East Sea of Vietnam through the Ensemble-Based Data Assimilation System
- Author
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Dao Nguyen-Quynh Hoa, Tran-Tan Tien, Nguyen-Y Nhu, and Thi Lan Dao
- Subjects
tropical cyclogenesis ,ensemble prediction system ,data assimilation ,Meteorology. Climatology ,QC851-999 - Abstract
In this study, we conducted experiments to assess the forecasting capabilities for tropical cyclone (TC) genesis over the east sea of Vietnam using the ensemble-based data assimilation system (EPS-DA) by WRF-LETKF. These experiments covered forecast lead times of up to 5 days and spanned a period from 2012 to 2019, involving a total of 45 TC formation events. The evaluation involved forecast probability assessments and positional and timing error analysis. Results indicated that successful forecasting depends on the lead time and initial condition quality. For TC formation from an embryo vortex to tropical depression intensity, the EPS-DA system demonstrated improved accuracy as the forecast cycle approached the actual formation time. TC centers converged towards observed locations, highlighting the potential of assimilation up to 5 days before formation. We examined statistical variations in dynamic and thermodynamic variables relevant to TC processes, offering an objective system assessment. Our study emphasized that early warnings of TC development appear linked to formation-time environmental conditions, particularly strong vorticity and enhanced moisture processes.
- Published
- 2023
- Full Text
- View/download PDF
8. Application of Kalman Filter and Breeding Ensemble Technique to Forecast the Tropical Cyclone Activity
- Author
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Thanh, Cong, primary, Nguyen Quynh Hoa, Dao, additional, and Tan Tien, Tran, additional
- Published
- 2021
- Full Text
- View/download PDF
9. Impact of the environmental protection tax on household welfare in Vietnam
- Author
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Nguyen Quynh, Hoa, primary, Ngo Quoc, Dung, additional, Pham Ngoc, Toan, additional, and Nguyen Thi Thu, Lien, additional
- Published
- 2023
- Full Text
- View/download PDF
10. Counter-Institutional Identities and Product Innovation: “Core-Satellite” as a Response to Competing Logics Shaping Artisan Businesses
- Author
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Nguyen, Van Dai, primary, Thuc Anh Phan, Thi, additional, Nguyen, Thi Tuyet Mai, additional, Nguyen, Quynh Hoa, additional, Van Trinh, Mai, additional, Long Pham, Sy, additional, and Nhat Vo, Hong, additional
- Published
- 2023
- Full Text
- View/download PDF
11. Online Language Testing and Assessment in the Pandemic: Opinions from Test Administrators and Examiners
- Author
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Nguyen, Thi Quynh Yen, primary, Tran, Thi Thu Hien, additional, Nguyen, Thi Ngoc Quynh, additional, Nguyen, Thi Phuong Thao, additional, Nguyen, Thi Chi, additional, Bui, Thien Sao, additional, and Nguyen, Quynh Hoa, additional
- Published
- 2022
- Full Text
- View/download PDF
12. Assessing the Impacts of Augmented Observations on the Forecast of Typhoon Wutip’s (2013) Formation Using the Ensemble Kalman Filter
- Author
-
Chanh Kieu, Cong Thanh, Tran Tan Tien, and Dao Nguyen-Quynh Hoa
- Subjects
Atmospheric Science ,Meteorology ,Computer science ,Typhoon ,Ensemble Kalman filter ,Kalman filter - Abstract
In this study, the impacts of different augmented observations on forecasts of Typhoon Wutip’s (2013) formation are examined. Using the local ensemble transformed Kalman filter (LETKF) implemented for the Weather Research and Forecasting (WRF) Model, it is found that the prediction of Wutip’s formation location and timing is strongly governed by the strength of a monsoon trough that extends from the Bay of Bengal to the Philippine Sea. By properly capturing the strength of the monsoon trough after assimilating augmented observations available during Wutip’s early stage, the WRF Model could provide better forecasts of Wutip’s formation location and timing as compared to the forecasts initialized directly from global model analyses. Among different types of augmented observations, the satellite atmospheric motion wind vector (AMV) maintained by the Cooperative Institute for Meteorological Satellite Studies (CIMSS) appears to be the most critical in enhancing the large-scale representation of the monsoon trough. The benefit of augmented observations in Wutip’s formation forecast is most apparent at about 36 h prior to the observed formation time. At the shorter 24-h lead time, there is, however, no clear benefit of augmented observations in predicting the timing and the location of Wutip’s formation due to better global analyses. The results obtained in this study demonstrate the vital role of the CIMSS-AMV data in improving the large-scale environment required for TC formation that one should take into account for real-time TC forecasts.
- Published
- 2020
13. Application of Kalman Filter and Breeding Ensemble Technique to Forecast the Tropical Cyclone Activity
- Author
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Tran Tan Tien, Cong Thanh, and Dao Nguyen Quynh Hoa
- Subjects
010504 meteorology & atmospheric sciences ,Meteorology ,Environmental science ,Kalman filter ,Tropical cyclone ,010502 geochemistry & geophysics ,01 natural sciences ,0105 earth and related environmental sciences - Abstract
Tropical cyclone (TC) is one of the major meteorology disasters, as they lead to deaths, destroy the infrastructure and the environment. Therefore, how to improve the predictability of TC’s activities, such as formation, track, and intensity, is very important and is considered an important task for current operational predicting TC centers in many countries. However, predicting TC’s activities has remained a big challenge for meteorologists due to our incomplete understanding of the multiscale interaction of TCs with the ambient environment and the limitation of numerical weather forecast tools. Hence, this chapter will exhibit some techniques to improve the ability to predict the formation and track of TCs using an ensemble prediction system. Particularly, the Local Ensemble Transform Kalman Filter (LETKF) scheme and its implementation in the WRF Model, as well as the Vortex tracking method that has been applied for the forecast of TCs formation, will be presented in subSection 1. Application of Breeding Ensemble to Tropical Cyclone Track Forecasts using the Regional Atmospheric Modeling System (RAMS) model will be introduced in subSection 2.
- Published
- 2021
14. Vocation Education Quality from Demand Side’s Perspective: The Case of Transport Technology Universities in the North of Vietnam
- Author
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Phung Chu Hoang and Nguyen Quynh Hoa
- Subjects
Demand side ,Political science ,Educational quality ,Perspective (graphical) ,Marketing - Abstract
Quality outcomes from vocational education and training (VET) are fundamental to ensuring a skilled workforce and supporting a productive economy. The quality of vocational training from the demand’s perspective is defined as meeting the customer specification, needs or requirements. Using the method of Exploratory Factor Analysis (EFA) and Multiple Regression Analysis to get the analytical results of 275 respondents as graduates of University of Transport and Communication, University of Transport Technology (the two universities training on transportation in the North of Vietnam), the results show that factors are measured by the observed variables in the study that ensure reliability and relevance. The descriptive statistics result of vocational training quality is 3.28, while all independent variables are at average level (between 3.1 to 3.48) with the highest value related to the quality of the teacher and the lowest are facilities and training programs and management capacity of university. However, the regression results show that the qualification of the teacher, material facilities and training program, management capacity and job opportunities at the training school do not affect the quality of the training while “Learners-NH” have a great positive effect and the labor market information has a negative effect on the training quality of the school significantly. Base on those data, some policy recommendations have been given out in order to improve the training quality of transport technology universities in the north of Vietnam in particular and the vocational training quality of Vietnam in general.
- Published
- 2019
15. A NEEDS ANALYSIS OF VIETNAMESE USERS OF JAPANESE, KOREAN, AND CHINESE LANGUAGES
- Author
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Nguyen Quynh Hoa, Nguyen Thi Chi, Nguyen Thi Phuong Thao, Bui Thien Sao, Tran Thi Thu Hien, and Nguyen Thi Ngoc Quynh
- Abstract
Playing a vital role in the process of developing a test, needs analysis is often paid attention to in the first phases of planning language tests, especially large-scale ones. In the context of the project entitled “Developing Standardized Tests of Proficiency for Vietnamese Users of Japanese, Korean, and Chinese”, a needs analysis of Vietnamese users of Japanese, Korean, and Chinese was implemented. Specifically, the reported study’s goal was to investigate the activities in which Vietnamese adults frequently use their skills of Japanese, Korean, and Chinese and examine whether there were differences across activities and languages. Surveys were established with questions of frequency on particular activities either suggested by the researchers or proposed by the respondents themselves. Collected responses were analyzed using descriptive statistics and ANOVA. The results disclosed the extent to which language users utilized their language skills in different activities and the significant differences in the use frequency across different activities within each language and across languages for particular activities. The findings have served as a strong foundation and useful reference for the task design in the test development phase of the project.
- Published
- 2021
16. Gaps between International Tourists’ Attitudes and Behaviours towards Japanese Heritage Tourism and Government Policymakers’ Views - Opportunities for Tourism Innovation Post COVID-19
- Author
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Nguyen, Quynh Hoa, primary and Kazem, Vafadari, primary
- Published
- 2021
- Full Text
- View/download PDF
17. THE EFFECTIVENESS OF VSTEP.3-5 SPEAKING RATER TRAINING
- Author
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Bui Thien Sao, Nguyen Thi Quynh Yen, Nguyen Thi Phuong Thao, Nguyen Thi Chi, Tran Thi Thu Hien, Nguyen Thi Ngoc Quynh, and Nguyen Quynh Hoa
- Subjects
medicine.medical_specialty ,Physical therapy ,medicine ,Rater training ,Psychology - Abstract
Playing a vital role in assuring reliability of language performance assessment, rater training has been a topic of interest in research on large-scale testing. Similarly, in the context of VSTEP, the effectiveness of the rater training program has been of great concern. Thus, this research was conducted to investigate the impact of the VSTEP speaking rating scale training session in the rater training program provided by University of Languages and International Studies - Vietnam National University, Hanoi. Data were collected from 37 rater trainees of the program. Their ratings before and after the training session on the VSTEP.3-5 speaking rating scales were then compared. Particularly, dimensions of score reliability, criterion difficulty, rater severity, rater fit, rater bias, and score band separation were analyzed. Positive results were detected when the post-training ratings were shown to be more reliable, consistent, and distinguishable. Improvements were more noticeable for the score band separation and slighter in other aspects. Meaningful implications in terms of both future practices of rater training and rater training research methodology could be drawn from the study.
- Published
- 2020
18. Assessing the Impacts of Augmented Observations on the Forecast of Typhoon Wutip’s (2013) Formation Using the Ensemble Kalman Filter
- Author
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Tien, Tran Tan, primary, Nguyen-Quynh Hoa, Dao, additional, Thanh, Cong, additional, and Kieu, Chanh, additional
- Published
- 2020
- Full Text
- View/download PDF
19. Experiments on Using WRF Model data Assimilation of Coupled 3DVAR – LETKF in Predicting the Geneses of Tropical Cyclones in the Vietnamese East Sea
- Author
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Dao Nguyen Quynh Hoa and Tran Tan Tien
- Subjects
Data assimilation ,Weather Research and Forecasting Model ,Vietnamese ,Climatology ,language ,Environmental science ,Tropical cyclone ,language.human_language - Abstract
In this research, several experiments using WRF to research the geneses of tropical cyclonesby data assimilation of coupled 3DVAR (3-dimensional variation) – LETKF (Local Ensemble Transform Kalman filter) have been processed. The analysis field after data assimilation procedure with observational information from synop, METAR, ships, soundings,... database produced from 36h before the recorded tropical cyclogeneses from recorded database with 72-days forecasts. The resulted analysis sea level pressure (SLP) fields were compared to the inital fields from control forecast (CTL), which shown the anomalous high pressure of +0.4mb in the area surrounding the actual genesis locations. The SLP and wind fields at 10-meter level in the WUTIP 2013 case has been using as an example of the divergence and diversity of multiple members’ tropical cyclone development. Key words: tropical cyclones, tropical cyclogenesis, WRF, data assimilation, 3DVAR, LETKF
- Published
- 2018
20. A Potential Way to Decrease the Know-Do Gap in Hospital Infection Control in Vietnam: 'Providing Specific Figures on Healthcare-Associated Infections to the Hospital Staff Can ‘Wake Them Up’ to Change Their Behaviour'
- Author
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Nguyen Thi Kim Chuc, La Thi Quynh Lien, Ashok J. Tamhankar, Cecilia Stålsby Lundborg, Eva Johansson, Nguyen Thi Minh Thoa, Ho Dang Phuc, Pham Thi Lan, and Nguyen Quynh Hoa
- Subjects
Adult ,Male ,Rural Population ,Health Knowledge, Attitudes, Practice ,Urban Population ,Attitude of Health Personnel ,Health, Toxicology and Mutagenesis ,media_common.quotation_subject ,qualitative study ,lcsh:Medicine ,030501 epidemiology ,Article ,03 medical and health sciences ,perceptions ,0302 clinical medicine ,hospital staff ,Nursing ,Hygiene ,healthcare-associated infection ,Intervention (counseling) ,Health care ,Infection control ,Medicine ,Humans ,030212 general & internal medicine ,media_common ,Cross Infection ,business.industry ,know-do gap ,lcsh:R ,Public Health, Environmental and Occupational Health ,Workload ,Focus Groups ,Middle Aged ,Focus group ,infection control ,Personnel, Hospital ,Vietnam ,Content analysis ,Female ,0305 other medical science ,business ,Qualitative research - Abstract
Adequate infection control plays a key role in preventing healthcare-associated infections (HAIs). This study aimed to explore staff perceptions of hospital infection control in a rural and an urban hospital in Vietnam. Individual interviews were conducted with hospital managers, and focus group discussions were conducted with doctors, nurses and cleaning workers separately. Content analysis was applied. An interview guide including discussion points on HAIs, hand hygiene and healthcare waste management was used. Generally, the staff were knowledgeable of hospital infection control, but they were not aware of the situation in their own hospital, and infection control practices in the hospitals remained poor. Reported difficulties in infection control included lack of resources, poor awareness and patient overload. A main theme emerged: &lsquo, Making data on HAIs available for health workers can improve their awareness and motivate them to put their existing knowledge into practice, thus decreasing the know-do gap in infection control&rsquo, This could be a feasible intervention to improve infection control practice in the hospitals with limited resources, high workload and patient overload.
- Published
- 2018
21. Knowledge and self-reported practices of infection control among various occupational groups in a rural and an urban hospital in Vietnam
- Author
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Nguyen Thi Minh Thoa, Nguyen Thi Kim Chuc, Cecilia Stålsby Lundborg, Emilia Riggi, Pham Thi Lan, Nguyen Quynh Hoa, Ashok J. Tamhankar, and La Thi Quynh Lien
- Subjects
Adult ,Male ,medicine.medical_specialty ,Occupational group ,Hospitals, Rural ,lcsh:Medicine ,Nurses ,Pilot Projects ,030501 epidemiology ,Article ,03 medical and health sciences ,Hospitals, Urban ,0302 clinical medicine ,Medical Staff, Hospital ,Humans ,Infection control ,Medicine ,030212 general & internal medicine ,lcsh:Science ,Infection Control ,Multidisciplinary ,business.industry ,lcsh:R ,Middle Aged ,Test (assessment) ,Median test ,Cross-Sectional Studies ,Mood ,Vietnam ,Continuing professional development ,Family medicine ,lcsh:Q ,Female ,Self Report ,Ordered logit ,0305 other medical science ,business ,Urban hospital - Abstract
Staff practice, driven by knowledge, plays a decisive role in hospital infection control. This study aimed to assess and compare knowledge and self-reported practices of infection control among various occupational groups in a rural and an urban hospital in Vietnam. Questionnaires consisting of items on knowledge and practices were collected from 339 hospital staff with varying occupations. For analysis, total knowledge or practice score ranged from 0–15. Mood’s median test was performed to compare median scores. Post-hoc analysis of ordinal logistic regression models was applied to test differences in scores among occupational groups. The majority of hospital staff had good or adequate knowledge (median score: rural = 11.8; urban = 12), but the score range was wide (1.4–14.5). Self-reported practices in the urban hospital were likely to be better than in the rural one (p = 0.003). Self-reported practices yet not completely satisfactory, indicating the need for continuing professional development in both settings. Overall, cleaners had lower scores than both physicians and nurses, highlighting the need for tailored education in this topic. Future infection control strategies within the hospitals might want to assess the difference between the staff’s self-reported practice and their actual real practice. These findings can be of value in many other similar settings.
- Published
- 2018
22. A study on relationship between cultural industry and economic growth in Vietnam
- Author
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Ngo, Thang Loi, primary, Tran, Thi Van Hoa, additional, Tran, Manh Dung, additional, Nguyen, Quynh Hoa, additional, and Hoang, Van Hoa, additional
- Published
- 2019
- Full Text
- View/download PDF
23. Experiments on Using WRF Model data Assimilation of Coupled 3DVAR – LETKF in Predicting the Geneses of Tropical Cyclones in the Vietnamese East Sea
- Author
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Tan Tien, Tran, primary and Nguyen Quynh Hoa, Dao, primary
- Published
- 2018
- Full Text
- View/download PDF
24. Antibiotic Resistance and Antibiotic Resistance Genes in Escherichia coli Isolates from Hospital Wastewater in Vietnam
- Author
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Nguyen Thi Minh Thoa, Nguyen Thi Kim Chuc, Cecilia Stålsby Lundborg, Pham Hong Nhung, Vishal Diwan, La Thi Quynh Lien, Ashok J. Tamhankar, Pham Thi Lan, and Nguyen Quynh Hoa
- Subjects
0301 basic medicine ,Imipenem ,antibiotic resistance ,medicine.drug_class ,Health, Toxicology and Mutagenesis ,030106 microbiology ,Antibiotics ,Wastewater ,Biology ,medicine.disease_cause ,Article ,beta-Lactamases ,Microbiology ,03 medical and health sciences ,antibiotic resistance genes ,Antibiotic resistance ,Drug Resistance, Multiple, Bacterial ,Escherichia coli ,medicine ,Public Health, Environmental and Occupational Health ,qepA ,Drug Resistance, Microbial ,biology.organism_classification ,blaCTX-M ,blaTEM ,hospital wastewater ,Hospitals ,Anti-Bacterial Agents ,Ciprofloxacin ,Multiple drug resistance ,Vietnam ,Bacteria ,medicine.drug - Abstract
The environmental spread of antibiotic-resistant bacteria has been recognised as a growing public health threat for which hospitals play a significant role. The aims of this study were to investigate the prevalence of antibiotic resistance and antibiotic resistance genes (ARGs) in Escherichia coli isolates from hospital wastewater in Vietnam. Wastewater samples before and after treatment were collected using continuous sampling every month over a year. Standard disk diffusion and E-test were used for antibiotic susceptibility testing. Extended-spectrum beta-lactamase (ESBL) production was tested using combined disk diffusion. ARGs were detected by polymerase chain reactions. Resistance to at least one antibiotic was detected in 83% of isolates; multidrug resistance was found in 32%. The highest resistance prevalence was found for co-trimoxazole (70%) and the lowest for imipenem (1%). Forty-three percent of isolates were ESBL-producing, with the blaTEM gene being more common than blaCTX-M. Co-harbouring of the blaCTX-M, blaTEM and qepA genes was found in 46% of isolates resistant to ciprofloxacin. The large presence of antibiotic-resistant E. coli isolates combined with ARGs in hospital wastewater, even post-treatment, poses a threat to public health. It highlights the need to develop effective processes for hospital wastewater treatment plants to eliminate antibiotic resistant bacteria and ARGs.
- Published
- 2017
- Full Text
- View/download PDF
25. Antibiotic prescribing and dispensing for acute respiratory infections in children: effectiveness of a multi-faceted intervention for health-care providers in Vietnam
- Author
-
Cecilia Stålsby Lundborg, Nguyen Thi Kim Chuc, Ho Dang Phuc, Pham Thi Lan, and Nguyen Quynh Hoa
- Subjects
Adult ,Male ,Rural Population ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,health-care provider ,Adolescent ,Attitude of Health Personnel ,Health Personnel ,030231 tropical medicine ,Disease ,Drug Prescriptions ,Article ,Antibiotic prescribing ,03 medical and health sciences ,0302 clinical medicine ,Antibiotic resistance ,Antibiotics ,Surveys and Questionnaires ,Intervention (counseling) ,Health care ,medicine ,Global health ,Humans ,030212 general & internal medicine ,Child ,Intensive care medicine ,Respiratory Tract Infections ,intervention ,Under-five ,business.industry ,Health Policy ,acute respiratory tract infections ,lcsh:Public aspects of medicine ,Infant, Newborn ,Public Health, Environmental and Occupational Health ,Infant ,Rural district ,lcsh:RA1-1270 ,Middle Aged ,Anti-Bacterial Agents ,respiratory tract diseases ,Vietnam ,Child, Preschool ,Family medicine ,Female ,Original Article ,business - Abstract
Background: Appropriate antibiotic use is vital to effectively contain antibiotic resistance and improve global health. Acute respiratory infections (ARIs) remain the leading cause of disease and death in children under five in low-income countries. Objective: To evaluate a multi-faceted intervention targeting health-care-providers’ (HCPs) knowledge, practical competences and practices regarding antibiotic use for ARIs. Methods: A multi-faceted educational intervention with a two-armed randomised controlled design targeting HCPs treating ARIs in children was conducted in Bavi district, a rural district in Northern Vietnam in 2010–2011. Thirty-two communes of the district were randomized into two arms, with 144 HCPs in the intervention arm and 160 in the control arm. The intervention, conducted over seven months, comprised: (i) education regarding appropriate-antibiotic use, (ii) case scenario discussion and (iii) poster distribution. Questionnaires to assess knowledge and dispensing/prescribing forms to assess practice were completed before-and after interventions. The main outcome measures were differences in improvement in knowledge and practice in the intervention and control group, respectively. Results: Knowledge improved in the intervention group for ARI aetiology by 28% (ΔDecrement control arm 10%), antibiotic use for mild ARIs by 15% (ΔDecrement control arm 13%) and for severe ARIs by 14% (ΔImprovement control arm 29%). Practical competence for a mild ARI case scenario improved in the intervention and control groups by 20% and 11%, respectively. Total knowledge score increased statistically in the intervention group (Δmean improvement 1.17); less so in the control group (Δmean improvement 0.48). Practice regarding antibiotics for mild ARIs improved by 28% in the intervention group (ΔDecrement control arm 3%). Conclusions: The intervention significantly improved HCPs’ knowledge of ARIs and practice of antibiotic use in treatment of ARIs. We suggest mixed method assessment and long-term follow-up of these interventions to enable better appreciation of the effects and effect sizes of our interventions.
- Published
- 2017
26. Assessing the Impacts of Augmented Observations on the Forecast of Typhoon Wutip’s (2013) Formation Using the Ensemble Kalman Filter.
- Author
-
Tran Tan Tien, Dao Nguyen-Quynh Hoa, Cong Thanh, and Chanh Kieu
- Subjects
- *
KALMAN filtering , *ATMOSPHERIC circulation , *METEOROLOGICAL satellites , *METEOROLOGICAL research , *WEATHER forecasting - Abstract
In this study, the impacts of different augmented observations on forecasts of Typhoon Wutip’s (2013) formation are examined. Using the local ensemble transformed Kalman filter (LETKF) implemented for the Weather Research and Forecasting (WRF) Model, it is found that the prediction of Wutip’s formation location and timing is strongly governed by the strength of a monsoon trough that extends from the Bay of Bengal to the Philippine Sea. By properly capturing the strength of the monsoon trough after assimilating augmented observations available during Wutip’s early stage, the WRF Model could provide better forecasts of Wutip’s formation location and timing as compared to the forecasts initialized directly from global model analyses. Among different types of augmented observations, the satellite atmospheric motion wind vector (AMV) maintained by the Cooperative Institute for Meteorological Satellite Studies (CIMSS) appears to be the most critical in enhancing the large-scale representation of the monsoon trough. The benefit of augmented observations in Wutip’s formation forecast is most apparent at about 36 h prior to the observed formation time. At the shorter 24-h lead time, there is, however, no clear benefit of augmented observations in predicting the timing and the location of Wutip’s formation due to better global analyses. The results obtained in this study demonstrate the vital role of the CIMSS-AMV data in improving the large-scale environment required for TC formation that one should take into account for real-time TC forecasts. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
27. Relationship between urban heat island effect and cicada density in metropolitan Seoul
- Author
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Nguyen Quynh Hoa
- Subjects
Geography ,Meteorology ,Physical geography ,Urban heat island ,Metropolitan area - Published
- 2016
28. Analysis of factors affecting Ho Chi Minh city’s office rental price using Hedonic model.
- Author
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Mottaeva, A., Melović, B., Le, Van Thuong, Nguyen, Quynh Hoa, and Nguyen, Van Toan
- Published
- 2018
- Full Text
- View/download PDF
29. Antibiotic sales in rural and urban pharmacies in northern Vietnam: an observational study
- Author
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Tran Khanh Toan, Nguyen Thi Kim Chuc, Do Thi Thuy Nga, Nguyen Thi Thuy Nguyen, Nguyen Quynh Hoa, Ho Dang Phuc, Heiman F. L. Wertheim, Peter Horby, Hoang Thi Loan, Nguyen Van Yen, Nguyen Phuong Hoa, and Nguyen Van Kinh
- Subjects
Rural Population ,Health Knowledge, Attitudes, Practice ,Urban Population ,Nonprescription Drugs ,Pharmacy ,Community ,Pharmacology ,Dispensing ,Prescription ,Antibiotic resistance ,Surveys and Questionnaires ,Environmental health ,Drug Resistance, Bacterial ,Medicine ,Revenue ,Pharmacology (medical) ,Medical prescription ,Pharmacies ,2. Zero hunger ,Practice ,business.industry ,Commerce ,Antibiotic ,1. No poverty ,Total revenue ,Anti-Bacterial Agents ,3. Good health ,Incentive ,Vietnam ,Over-the-counter ,Rural area ,business ,Research Article - Abstract
BACKGROUND: The irrational overuse of antibiotics should be minimized as it drives the development of antibiotic resistance, but changing these practices is challenging. A better understanding is needed of practices and economic incentives for antibiotic dispensing in order to design effective interventions to reduce inappropriate antibiotic use. Here we report on both quantitative and qualitative aspects of antibiotic sales in private pharmacies in northern Vietnam. METHOD: A cross-sectional study was conducted in which all drug sales were observed and recorded for three consecutive days at thirty private pharmacies, 15 urban and 15 rural, in the Hanoi region in 2010. The proportion of antibiotics to total drug sales was assessed and the revenue was calculated for rural and urban settings. Pharmacists and drug sellers were interviewed by a semi-structured questionnaire and in-depth interviews to understand the incentive structure of antibiotic dispensing. RESULTS: In total 2953 drug sale transactions (2083 urban and 870 rural) were observed. Antibiotics contributed 24% and 18% to the total revenue of pharmacies in urban and rural, respectively. Most antibiotics were sold without a prescription: 88% in urban and 91% in rural pharmacies. The most frequent reported reason for buying antibiotics was cough in the urban setting (32%) and fever in the rural area (22%). Consumers commonly requested antibiotics without having a prescription: 50% in urban and 28% in rural area. The qualitative data revealed that drug sellers and customer's knowledge of antibiotics and antibiotic resistance were low, particularly in rural area. CONCLUSION: Over the counter sales of antibiotic without a prescription remains a major problem in Vietnam. Suggested areas of improvement are enforcement of regulations and pricing policies and educational programs to increase the knowledge of drug sellers as well as to increase community awareness to reduce demand-side pressure for drug sellers to dispense antibiotics inappropriately.
- Published
- 2014
30. Antibiotics in Wastewater of a Rural and an Urban Hospital before and after Wastewater Treatment, and the Relationship with Antibiotic Use—A One Year Study from Vietnam
- Author
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Nguyen Thi Minh Thoa, Ho Dang Phuc, Ashok J. Tamhankar, Nguyen Thi Kim Chuc, La Thi Quynh Lien, Vishal Diwan, Nguyen Thanh Dat, Nguyen Quynh Hoa, and Cecilia Stålsby Lundborg
- Subjects
medicine.medical_specialty ,010504 meteorology & atmospheric sciences ,medicine.drug_class ,Health, Toxicology and Mutagenesis ,Antibiotics ,lcsh:Medicine ,Wastewater ,010501 environmental sciences ,Waste Disposal, Fluid ,01 natural sciences ,Article ,Toxicology ,antibiotic residues ,hospital wastewater ,ciprofloxacin ,metronidazole ,Hospitals, Urban ,Antibiotic resistance ,medicine ,Humans ,Intensive care medicine ,Effluent ,0105 earth and related environmental sciences ,business.industry ,lcsh:R ,Solid Phase Extraction ,Public Health, Environmental and Occupational Health ,Drug Utilization ,Anti-Bacterial Agents ,Ciprofloxacin ,Metronidazole ,Vietnam ,Sewage treatment ,business ,Water Pollutants, Chemical ,Environmental Monitoring ,medicine.drug ,Urban hospital - Abstract
Hospital effluents represent an important source for the release of antibiotics and antibiotic resistant bacteria into the environment. This study aims to determine concentrations of various antibiotics in wastewater before and after wastewater treatment in a rural hospital (60 km from the center of Hanoi) and in an urban hospital (in the center of Hanoi) in Vietnam, and it aims to explore the relationship between antibiotic concentrations in wastewater before wastewater treatment and quantities of antibiotics used in the rural hospital, over a period of one year in 2013. Water samples were collected using continuous sampling for 24 h in the last week of every month. The data on quantities of antibiotics delivered to all inpatient wards were collected from the Pharmacy department in the rural hospital. Solid-phase extraction and high performance liquid chromatography-tandem mass spectrometry were used for chemical analysis. Significant concentrations of antibiotics were present in the wastewater both before and after wastewater treatment of both the rural and the urban hospital. Ciprofloxacin was detected at the highest concentrations in the rural hospital’s wastewater (before treatment: mean = 42.8 µg/L; after treatment: mean = 21.5 µg/L). Metronidazole was detected at the highest concentrations in the urban hospital’s wastewater (before treatment: mean = 36.5 µg/L; after treatment: mean = 14.8 µg/L). A significant correlation between antibiotic concentrations in wastewater before treatment and quantities of antibiotics used in the rural hospital was found for ciprofloxacin (r = 0.78; p = 0.01) and metronidazole (r = 0.99; p < 0.001).
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- 2016
31. Unnecessary antibiotic use for mild acute respiratory infections during 28-day follow-up of 823 children under five in rural Vietnam
- Author
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Nguyen Quynh Hoa, Cecilia Stålsby Lundborg, Nguyen Thi Kim Chuc, Bo Eriksson, Mattias Larsson, and Ho Dang Phuc
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Male ,Pediatrics ,medicine.medical_specialty ,medicine.drug_class ,Antibiotics ,Rural Health ,Surveys and Questionnaires ,medicine ,Humans ,Prospective Studies ,Antibiotic use ,Prospective cohort study ,Respiratory Tract Infections ,Respiratory tract infections ,Under-five ,business.industry ,Public Health, Environmental and Occupational Health ,Respiratory infection ,Infant ,General Medicine ,respiratory tract diseases ,Anti-Bacterial Agents ,Infectious Diseases ,Caregivers ,Vietnam ,Child, Preschool ,Acute Disease ,Community setting ,Parasitology ,Female ,Guideline Adherence ,business ,Healthcare providers - Abstract
Few prospective studies regarding antibiotic use for mild acute respiratory infections (ARI) have been conducted in community settings. This paper aimed to assess knowledge of children's caregivers and actual antibiotic use for children under five and to identify factors associated with antibiotic treatment for mild ARIs. Caregivers in 828 households in Bavi, Vietnam, were interviewed using a structured questionnaire assessing both knowledge and practice. Subsequently, 823 children were followed for 28 days to collect information regarding symptoms and drug use. For management of ARIs, only 13% of caregivers demonstrated correct overall knowledge in accordance with standard guidelines. The symptoms of the most recent illness were consistent with mild ARI in 79% of cases, and antibiotics were used in 71% of these. During the 28-day period, 62% of children had been given antibiotics and 63% of antibiotic courses were used for mild ARIs. One-half of the mild ARI episodes and 63% of the children with mild ARIs were treated with antibiotics. Most of the unnecessary antibiotic treatment was recommended by healthcare providers (82%). Most of the children had been administered antibiotics for common colds, although most caregivers believed that antibiotics were not required. Antibiotics were unnecessarily recommended at health facilities in the area.
- Published
- 2010
32. Decreased Streptococcus pneumoniae susceptibility to oral antibiotics among children in rural Vietnam: a community study
- Author
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Cecilia Stålsby Lundborg, Ho Dang Phuc, Bo Eriksson, Nguyen Quynh Hoa, Nguyen Tk Chuc, Mattias Larsson, and Nguyen Vu Trung
- Subjects
Male ,Rural Population ,medicine.medical_specialty ,Cefotaxime ,medicine.drug_class ,Antibiotics ,Erythromycin ,Microbial Sensitivity Tests ,Drug resistance ,medicine.disease_cause ,Pneumococcal Infections ,lcsh:Infectious and parasitic diseases ,Antibiotic resistance ,Drug Resistance, Multiple, Bacterial ,Internal medicine ,Streptococcus pneumoniae ,medicine ,Humans ,lcsh:RC109-216 ,Intensive care medicine ,business.industry ,Infant ,Amoxicillin ,medicine.disease ,Anti-Bacterial Agents ,Pneumococcal infections ,Infectious Diseases ,Vietnam ,Child, Preschool ,Female ,business ,Research Article ,medicine.drug - Abstract
Background Streptococcus pneumoniae is the most significant bacterial cause of community-acquired pneumonia among children under five years worldwide. Updated resistance information of S. pneumoniae among children is essential to adjust the recommendations for empirical treatment of community-acquired pneumonia, which will have immense implications for local and global health. This study investigated the prevalence of antibiotic resistance in isolated strains of S. pneumoniae and relationship with antibiotic use and demographic factors of children under five in rural Vietnam in 2007. Methods In Bavi district, 847 children 6 to 60 months were selected from 847 households. The main child-caregivers in the households were interviewed weekly using structured questionnaires to collect information of daily illness symptoms and drug use for the selected child over a four-week period (from March through June 2007). In the 3rd week, the children were invited for a clinical examination and to collect nasopharyngeal samples for S. pneumoniae identification. Etest and disk diffusion were used to test antibiotic susceptibility. Results Of 818 participating children, 258 (32%) had ongoing respiratory infections, 421 (52%) carried S. pneumoniae, and 477 (58%) had used antibiotics within the previous three weeks. Of the 421 isolates, 95% were resistant to at least one antibiotic (401/421). Resistance to co-trimoxazole, tetracycline, phenoxymethylpenicillin, erythromycin and ciprofloxacin was 78%, 75%, 75%, 70% and 28%, respectively. Low resistance was noted for amoxicillin (4%), benzylpenicillin (4%), and cefotaxime (2%). The intermediate resistance to amoxicillin was 32%. Multidrug-resistance was seen in 60%. The most common pattern was co-resistance to co-trimoxazole, tetracycline and erythromycin. The proportion of children carrying resistant bacteria was higher among the children who had used antibiotics in the previous three weeks. Conclusions Resistance to commonly used antibiotics and multidrug-resistance of S. pneumoniae in the area is remarkably high. High-dose amoxicillin is the only investigated oral antibiotic that can possibly be used for treatment of community-acquired pneumococcal infections. Strategies to promote appropriate prescribing and dispensing of effective antibiotics should be immediately implemented for the benefit of local and global health.
- Published
- 2010
33. Antibiotics and paediatric acute respiratory infections in rural Vietnam: health-care providers' knowledge, practical competence and reported practice
- Author
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Nguyen Quynh Hoa, Mattias Larson, Bo Eriksson, Nguyen Thi Kim Chuc, Cecilia Lundborg Stålsby, and Nguyen Vu Trung
- Subjects
Adult ,Male ,medicine.medical_specialty ,Pediatrics ,Health Knowledge, Attitudes, Practice ,medicine.drug_class ,Health Personnel ,Antibiotics ,Psychological intervention ,Rural Health ,Surveys and Questionnaires ,Health care ,medicine ,Humans ,Medical prescription ,Intensive care medicine ,Respiratory Tract Infections ,Antibacterial agent ,Under-five ,business.industry ,Public Health, Environmental and Occupational Health ,Infant ,Common cold ,Middle Aged ,medicine.disease ,Anti-Bacterial Agents ,Infectious Diseases ,Cross-Sectional Studies ,Vietnam ,Child, Preschool ,Acute Disease ,Practice Guidelines as Topic ,Parasitology ,Female ,Clinical Competence ,Guideline Adherence ,Rural area ,business - Abstract
OBJECTIVE To assess knowledge, practical competence and reported practices among health-care providers about antibiotics to treat acute respiratory infections in children under five in rural Vietnam. METHOD Health-care providers prescribing or dispensing western drugs for children self-completed a structured questionnaire. Recommendations concerning antibiotic use from WHO and national guidelines were used to assess the appropriateness of reported treatment of acute respiratory infections. RESULTS Ninety-six per cent of 409 eligible health care providers participated. Only 27% demonstrated correct knowledge regarding the consequences of resistance. Seventy-nine per cent would use antibiotics for common colds with fever, and 21% in cases with no fever. Nineteen per cent had overall knowledge compliant with recommended guidelines. Stated antibiotic use in written scenarios for common colds (81%) was not significantly different from that for non-referral cases of pneumonia (87%). The proportion of antibiotic use in the common cold scenario was significantly lower among health-care providers who had the correct overall knowledge. According to reported symptoms from the most recent encounter with a sick child, the diseases seen were 62% mild acute respiratory infections, 19% severe, and 19% non-respiratory infections. Among those, antibiotics, most commonly beta-lactams, were used in 90%, 87% and 78% of cases, respectively. CONCLUSIONS Antibiotics are often prescribed or dispensed to treat common colds. Interventions to change prescribing and dispensing practices should be developed and implemented in collaboration with local and national paediatricians. Continuous training of health-care providers, particularly drug sellers, is important.
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- 2009
34. Drug use and health-seeking behavior for childhood illness in Vietnam--a qualitative study
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Ann Öhman, Nguyen Thi Kim Chuc, Nguyen Quynh Hoa, and Cecilia Stålsby Lundborg
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Program evaluation ,Adult ,Male ,medicine.medical_specialty ,Population ,Developing country ,Child Welfare ,Compliance (psychology) ,Health care ,medicine ,Humans ,education ,Psychiatry ,Child ,Aged ,Aged, 80 and over ,education.field_of_study ,business.industry ,Health Policy ,Focus Groups ,Middle Aged ,Patient Acceptance of Health Care ,Focus group ,Anti-Bacterial Agents ,Vietnam ,Family medicine ,Child, Preschool ,Female ,business ,Qualitative research ,Meaning (linguistics) - Abstract
Objectives: To describe and understand health-seeking behavior and drug use among caregivers, in particular antibiotics, for childhood illnesses in Vietnam. Methods: A total of six focus group discussions were conducted with child care providers. A thematised interview guide was used and qualitative content analysis was applied. Meaning units in the texts dealing with the same content material were identified, condensed and compared until several emerging themes were found. Finally, similarities and differences in the views between rural and urban groups were described. Results: Self-treatment and self-medication were prominent in the urban groups, whereas compliance and trust in doctors were more common among the rural participants. Misuse and misconceptions regarding the properties of drugs were reported leading to worries about irrational drug use in the community. Despite the widespread use of private services in both areas, the public health service was reported to be the most trusted recourse for serious cases. Conclusions: Qualitatively different ways of using drug and health care services are reported for childhood sickness in rural and urban Vietnam. These results provide rich information for the development of quantitative studies on drug use for children and point to the need to involve all health facilities in consideration. © 2006 Elsevier Ireland Ltd. All rights reserved.
- Published
- 2005
35. Antibiotic Resistance and Antibiotic Resistance Genes in Escherichia coli Isolates from Hospital Wastewater in Vietnam.
- Author
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La Thi Quynh Lien, Pham Thi Lan, Nguyen Thi Kim Chuc, Nguyen Quynh Hoa, Pham Hong Nhung, Nguyen Thi Minh Thoa, Diwan, Vishal, Tamhankar, Ashok J., and Lundborg, Cecilia Stålsby
- Published
- 2017
- Full Text
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36. High antibiotic use and resistance among children under five : acute respiratory infections : knowledge and behaviour of caregivers and healthcare providers in Vietnam
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Nguyen Quynh, Hoa and Nguyen Quynh, Hoa
- Abstract
Background: Increased bacterial resistance is threatening the therapeutic effectiveness of antibiotics. High level of antibiotic use is probably the main factor driving the emergence of resistance. Streptococcus pneumoniae is the most significant bacterial cause of community-acquired pneumonia, which is the leading cause of deaths among children under five worldwide. Main aim: To investigate proportion of antibiotic resistance and antibiotic use for acute respiratory infections (ARIs) among children under five, and describe knowledge and behaviour of caregivers and healthcare providers (HCPs) regarding antibiotic use for childhood illness in Vietnam. Methods: This thesis consists of quantitative and qualitative studies. In Papers I and III, 828 caregivers were interviewed using a structured questionnaire and 823 children under five were followed for a 28-day period to collect data on daily illness symptoms and drug use. Clinical examinations were done and nasopharyngeal samples were taken. Etest and disk-diffusion were used to test antibiotic susceptibility of 421 S. pneumoniae isolates. Paper II is a qualitative study with six focus group discussions with mothers, fathers and grandmothers. Paper IV used a self-completed structured questionnaire with 392 HCPs regarding management of children under five with ARIs. Results: Of the 421 pneumococcal isolates, 95% were resistant to at least one antibiotic and 60% were multidrug-resistant (I). The resistance to co-trimoxazole, tetracycline, phenoxymethylpenicillin, erythromycin and ciprofloxacin was 78%, 75%, 75%, 70% and 28%, respectively. Low resistance was noted for amoxicillin (4%), benzylpenicillin (4%), and cefotaxime (2%). The intermediate resistance to amoxicillin was 32%. Resistance to commonly used antibiotics was higher among children who had used antibiotics recently (I). Self-treatment was prominent among urban participants, whereas compliance and trust in physicians were more common among rural participants.
- Published
- 2010
37. Antibiotics in Wastewater of a Rural and an Urban Hospital before and after Wastewater Treatment, and the Relationship with Antibiotic Use--A One Year Study from Vietnam.
- Author
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La Thi Quynh Lien, Nguyen Quynh Hoa, Nguyen Thi Kim Chuc, Nguyen Thi Minh Thoa, Ho Dang Phuc, Vishal Diwan, Nguyen Thanh Dat, Tamhankar, Ashok J., and Stålsby Lundborg, Cecilia
- Published
- 2016
- Full Text
- View/download PDF
38. High prevalence of antibiotic resistance in commensal Escherichia coli among children in rural Vietnam
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Nguyen Vu Trung, Nguyen Quynh Hoa, Nguyen Thi Kim Chuc, Oliver J. Dyar, Mattias Larsson, Cecilia Stålsby Lundborg, and Ho Dang Phuc
- Subjects
Male ,Rural Population ,medicine.medical_specialty ,medicine.drug_class ,Antibiotics ,Drug resistance ,Microbial Sensitivity Tests ,Biology ,lcsh:Infectious and parasitic diseases ,Microbiology ,Feces ,Antibiotic resistance ,Medical microbiology ,Amp resistance ,Ampicillin ,Drug Resistance, Bacterial ,medicine ,Escherichia coli ,Prevalence ,Humans ,lcsh:RC109-216 ,Escherichia coli Infections ,Sulfamethoxazole ,Infant ,Drug Utilization ,Anti-Bacterial Agents ,Ciprofloxacin ,Infectious Diseases ,Vietnam ,Child, Preschool ,Carrier State ,Female ,medicine.drug ,Research Article - Abstract
Background Commensal bacteria represent an important reservoir of antibiotic resistance genes. Few community-based studies of antibiotic resistance in commensal bacteria have been conducted in Southeast Asia. We investigated the prevalence of resistance in commensal Escherichia coli in preschool children in rural Vietnam, and factors associated with carriage of resistant bacteria. Methods We tested isolates of E. coli from faecal samples of 818 children aged 6-60 months living in FilaBavi, a demographic surveillance site near Hanoi. Daily antibiotic use data was collected for participating children for three weeks prior to sampling and analysed with socioeconomic and demographic characteristics extracted from FilaBavi's re-census survey 2007. Descriptive statistics were generated, and a logistic regression model was used to identify contributions of the examined factors. Results High prevalences of resistance were found to tetracycline (74%), co-trimoxazole (68%), ampicillin (65%), chloramphenicol (40%), and nalidixic acid (27%). Two isolates were resistant to ciprofloxacin. Sixty percent of isolates were resistant to three or more antibiotics. Recent sulphonamide use was associated with co-trimoxazole resistance [OR 3.2, 95% CI 1.8-5.7], and beta-lactam use with ampicillin resistance [OR 1.8, 95% CI 1.3-2.4]. Isolates from children aged 6-23 months were more likely to be resistant to ampicillin [OR 1.8, 95% CI 1.3-2.4] and co-trimoxazole [OR 1.5, 95% CI 1.1-2.0]. Associations were identified between geographical areas and tetracycline and ampicillin resistance. Conclusions We present high prevalence of carriage of commensal E. coli resistant to commonly used antibiotics. The identified associations with recent antibiotic use, age, and geographical location might contribute to our understanding of carriage of antibiotic resistant commensal bacteria.
- Published
- 2012
39. Risk assessment for drug degradation products using physiologically-based pharmacokinetic models
- Author
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Nguyen, Quynh Hoa, primary
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40. Herpes simplex virus type 1 mutants containing the KOS strain ICP34.5 gene in place of the McKrae ICP34.5 gene have McKrae-like spontaneous reactivation but non-McKrae-like virulence
- Author
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Perng, Guey-Chuen, primary, Mott, Kevin R., additional, Osorio, Nelson, additional, Yukht, Ada, additional, Salina, Susan, additional, Nguyen, Quynh-Hoa, additional, Nesburn, Anthony B., additional, and Wechsler, Steven L., additional
- Published
- 2002
- Full Text
- View/download PDF
41. Antibiotic sales in rural and urban pharmacies in northern Vietnam: an observational study.
- Author
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Do Thi Thuy Nga, Nguyen Thi Kim Chuc, Nguyen Phuong Hoa, Nguyen Quynh Hoa, Nguyen Thi Thuy Nguyen, Hoang Thi Loan, Tran Khanh Toan, Ho Dang Phuc, Horby, Peter, Nguyen Van Yen, Nguyen Van Kinh, and Wertheim, Heiman F. L.
- Subjects
ANTIBIOTIC sales & prices ,DRUGSTORES ,DRUG resistance ,NONPRESCRIPTION drugs ,DRUG overdose - Abstract
Background: The irrational overuse of antibiotics should be minimized as it drives the development of antibiotic resistance, but changing these practices is challenging. A better understanding is needed of practices and economic incentives for antibiotic dispensing in order to design effective interventions to reduce inappropriate antibiotic use. Here we report on both quantitative and qualitative aspects of antibiotic sales in private pharmacies in northern Vietnam. Method: A cross-sectional study was conducted in which all drug sales were observed and recorded for three consecutive days at thirty private pharmacies, 15 urban and 15 rural, in the Hanoi region in 2010. The proportion of antibiotics to total drug sales was assessed and the revenue was calculated for rural and urban settings. Pharmacists and drug sellers were interviewed by a semi-structured questionnaire and in-depth interviews to understand the incentive structure of antibiotic dispensing. Results: In total 2953 drug sale transactions (2083 urban and 870 rural) were observed. Antibiotics contributed 24% and 18% to the total revenue of pharmacies in urban and rural, respectively. Most antibiotics were sold without a prescription: 88% in urban and 91% in rural pharmacies. The most frequent reported reason for buying antibiotics was cough in the urban setting (32%) and fever in the rural area (22%). Consumers commonly requested antibiotics without having a prescription: 50% in urban and 28% in rural area. The qualitative data revealed that drug sellers and customer's knowledge of antibiotics and antibiotic resistance were low, particularly in rural area. Conclusion: Over the counter sales of antibiotic without a prescription remains a major problem in Vietnam. Suggested areas of improvement are enforcement of regulations and pricing policies and educational programs to increase the knowledge of drug sellers as well as to increase community awareness to reduce demand-side pressure for drug sellers to dispense antibiotics inappropriately. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
42. Decreased Streptococcus pneumoniae susceptibility to oral antibiotics among children in rural Vietnam: a community study.
- Author
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Nguyen Quynh Hoa, Trung, Nguyen V., Larsson, Mattias, Eriksson, Bo, Phuc, Ho D., Chuc, Nguyen T. K., and Lundborg, Cecilia Stalsby
- Subjects
- *
STREPTOCOCCUS pneumoniae , *COMMUNITY-acquired infections , *JUVENILE diseases , *DISEASE susceptibility , *DRUG resistance in microorganisms - Abstract
Background: Streptococcus pneumoniae is the most significant bacterial cause of community-acquired pneumonia among children under five years worldwide. Updated resistance information of S. pneumoniae among children is essential to adjust the recommendations for empirical treatment of community-acquired pneumonia, which will have immense implications for local and global health. This study investigated the prevalence of antibiotic resistance in isolated strains of S. pneumoniae and relationship with antibiotic use and demographic factors of children under five in rural Vietnam in 2007. Methods: In Bavi district, 847 children 6 to 60 months were selected from 847 households. The main childcaregivers in the households were interviewed weekly using structured questionnaires to collect information of daily illness symptoms and drug use for the selected child over a four-week period (from March through June 2007). In the 3rd week, the children were invited for a clinical examination and to collect nasopharyngeal samples for S. pneumoniae identification. Etest and disk diffusion were used to test antibiotic susceptibility. Results: Of 818 participating children, 258 (32%) had ongoing respiratory infections, 421 (52%) carried S. pneumoniae, and 477 (58%) had used antibiotics within the previous three weeks. Of the 421 isolates, 95% were resistant to at least one antibiotic (401/421). Resistance to co-trimoxazole, tetracycline, phenoxymethylpenicillin, erythromycin and ciprofloxacin was 78%, 75%, 75%, 70% and 28%, respectively. Low resistance was noted for amoxicillin (4%), benzylpenicillin (4%), and cefotaxime (2%). The intermediate resistance to amoxicillin was 32%. Multidrug-resistance was seen in 60%. The most common pattern was co-resistance to co-trimoxazole, tetracycline and erythromycin. The proportion of children carrying resistant bacteria was higher among the children who had used antibiotics in the previous three weeks. Conclusions: Resistance to commonly used antibiotics and multidrug-resistance of S. pneumoniae in the area is remarkably high. High-dose amoxicillin is the only investigated oral antibiotic that can possibly be used for treatment of community-acquired pneumococcal infections. Strategies to promote appropriate prescribing and dispensing of effective antibiotics should be immediately implemented for the benefit of local and global health. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
43. Improved knowledge and reported practice regarding sexually transmitted infections among healthcare providers in rural Vietnam: a cluster randomised controlled educational intervention
- Author
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Nguyen Quynh Hoa, Ho Dang Phuc, Pham Thi Lan, Cecilia Stålsby Lundborg, and Nguyen Thi Kim Chuc
- Subjects
Adult ,Male ,Rural Population ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,Multivariate analysis ,Health Personnel ,Sexual Behavior ,Population ,education ,Sexually Transmitted Diseases ,Psychological intervention ,Pharmacist ,Reported practice ,Intervention ,Pharmacy ,Disease cluster ,Young Adult ,Surveys and Questionnaires ,Intervention (counseling) ,medicine ,Cluster Analysis ,Humans ,Aged ,education.field_of_study ,business.industry ,Middle Aged ,Treatment Outcome ,Knowledge ,Infectious Diseases ,Vietnam ,Family medicine ,Female ,Health education ,STI ,business ,Research Article ,Healthcare provider - Abstract
Background Healthcare providers (HCPs) play a critical role in controlling the spread of sexually transmitted infections (STI) through early and accurate diagnosis, appropriate treatment and prevention counselling. This study aimed to assess the effectiveness of an educational intervention about STI on knowledge and reported practice among HCPs and to explore which determinants may influence the intervention’s effects. Methods A cluster randomized controlled educational intervention was carried out in a rural district, Vietnam. 32 communes of the district were randomized into two arms, with 160 HCPs in an STI intervention arm and 144 in a control arm. The STI intervention comprised interactive training with basic STI knowledge, case scenarios, and poster distribution. Questionnaires to evaluate knowledge and reported practice were completed three times: before, during and after the intervention. Correct answer was scored as 1; “do not know”, incorrect answer was scored as 0. Univariate and multilevel multivariate analyses were applied. Results Of the maximum 56 points, the mean knowledge score increased significantly in the STI intervention arm and in the control arm post-intervention (37.2 to 48.4, and 32.7 to 41.7, respectively). In multivariate regression analysis, knowledge improvement in the intervention arm was significantly higher than that in the control arm (regression coefficient = 2.97, p = 0.008). Other factors which positively influenced the increase in knowledge were being between 35 and 50 years old, having intermediate professional training, being a pharmacist or working at a village level (regression coefficient: 2.81, 4.43, 5.53 and 7.91, respectively). Post-intervention, the mean reported practice score increased significantly in the STI intervention arm (from 17.6 to 21.8) and insignificantly in the control arm (maximum 36 points). Factors which positively influenced the increase in reported practice were being between 35 and 50 years old, having intermediate professional training, or working at a pharmacy/drugstore (regression coefficient: 2.15, 3.33 and 3.22, respectively). Conclusions This study indicates that an educational intervention including interactive training and multi-faceted interventions may be effective in improving STI knowledge and reported practice of HCPs at grassroots level, particularly among pharmacists, HCPs who work in villages or pharmacies/drugstores, and who initially have low STI knowledge. Electronic supplementary material The online version of this article (doi:10.1186/s12879-014-0646-5) contains supplementary material, which is available to authorized users.
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44. Application of Kalman Filter and Breeding Ensemble Technique to Forecast the Tropical Cyclone Activity
- Author
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Tan Tien, Tran, Thanh, Cong, and Nguyen Quynh Hoa, Dao
- Subjects
Science / Earth Sciences - Abstract
Tropical cyclone (TC) is one of the major meteorology disasters, as they lead to deaths, destroy the infrastructure and the environment. Therefore, how to improve the predictability of TC’s activities, such as formation, track, and intensity, is very important and is considered an important task for current operational predicting TC centers in many countries. However, predicting TC’s activities has remained a big challenge for meteorologists due to our incomplete understanding of the multiscale interaction of TCs with the ambient environment and the limitation of numerical weather forecast tools. Hence, this chapter will exhibit some techniques to improve the ability to predict the formation and track of TCs using an ensemble prediction system. Particularly, the Local Ensemble Transform Kalman Filter (LETKF) scheme and its implementation in the WRF Model, as well as the Vortex tracking method that has been applied for the forecast of TCs formation, will be presented in subSection 1. Application of Breeding Ensemble to Tropical Cyclone Track Forecasts using the Regional Atmospheric Modeling System (RAMS) model will be introduced in subSection 2.
- Published
- 2022
45. Unnecessary antibiotic use for mild acute respiratory infections during 28-day follow-up of 823 children under five in rural Vietnam.
- Author
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Nguyen QH, Nguyen TK, Ho D, Larsson M, Eriksson B, and Lundborg CS
- Subjects
- Acute Disease, Caregivers, Child, Preschool, Female, Guideline Adherence, Humans, Infant, Male, Prospective Studies, Respiratory Tract Infections diagnosis, Respiratory Tract Infections epidemiology, Rural Health, Surveys and Questionnaires, Vietnam epidemiology, Anti-Bacterial Agents administration & dosage, Respiratory Tract Infections drug therapy
- Abstract
Few prospective studies regarding antibiotic use for mild acute respiratory infections (ARI) have been conducted in community settings. This paper aimed to assess knowledge of children's caregivers and actual antibiotic use for children under five and to identify factors associated with antibiotic treatment for mild ARIs. Caregivers in 828 households in Bavi, Vietnam, were interviewed using a structured questionnaire assessing both knowledge and practice. Subsequently, 823 children were followed for 28 days to collect information regarding symptoms and drug use. For management of ARIs, only 13% of caregivers demonstrated correct overall knowledge in accordance with standard guidelines. The symptoms of the most recent illness were consistent with mild ARI in 79% of cases, and antibiotics were used in 71% of these. During the 28-day period, 62% of children had been given antibiotics and 63% of antibiotic courses were used for mild ARIs. One-half of the mild ARI episodes and 63% of the children with mild ARIs were treated with antibiotics. Most of the unnecessary antibiotic treatment was recommended by healthcare providers (82%). Most of the children had been administered antibiotics for common colds, although most caregivers believed that antibiotics were not required. Antibiotics were unnecessarily recommended at health facilities in the area., (Copyright © 2011 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2011
- Full Text
- View/download PDF
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