A Gram-stain-negative, oxidase- and catalase-positive, facultative anaerobic motile bacterium, designated strain OG9-811 T , was isolated from the gut of an oyster collected in the Yellow Sea, Republic of Korea. The strain grew at 10-37 °C, pH 6.0-9.0 and with 0.5-10% (w/v) NaCl. Phylogenetic analysis based on the 16S rRNA gene sequences revealed that strain OG9-811 T affiliated with the genus Vibrio , with the highest sequence similarity of 98.2% to Vibrio coralliilyticus ATCC BAA-450 T followed by Vibrio variabilis R-40492 T (98.0 %), Vibrio hepatarius LMG 20362 T (97.7 %) and Vibrio neptunius LMG 20536 T (97.6 %); other relatives were Vibrio tritonius JCM 16456 T (97.4 %), Vibrio fluvialis NBRC 103150 T (97.0 %) and Vibrio furnissii CIP 102972 T (97.0 %). The complete genome of strain OG9-811 T comprised two chromosomes of a total 4 807 684 bp and the G+C content was 50.2 %. Results of analysis based on the whole genome sequence showed the distinctiveness of strain OG9-811 T . The average nucleotide identity (ANI) values between strain OG9-811 T and the closest strains V. coralliilyticus ATCC BAA-450 T , V. variabilis R-40492 T , V. hepatarius LMG 20362 T , V. neptunius KCTC 12702 T , V. tritonius JCM 16456 T , V. fluvialis ATCC 33809 T and V. furnissi CIP 102972 T were 73.0, 72.6, 73.3, 73.0, 72.7, 78.5 and 77.8 %, respectively, while the digital DNA-DNA hybridization values between strain OG9-811 T and the above closely related strains were 20.8, 21.2, 20.8, 21.7, 20.7, 23.2 and 22.4 %, respectively. The major fatty acids of strain OG9-811 T were summed feature 3 (C 16:1 ω 7 c and/or C 16:1 ω 6 c ), summed feature 8 (C 18:1 ω6 c and/or C 18:1 ω 7 c ) and C 16:0 . The polar lipids contained phosphatidylethanolamine, phosphatidylglycerol and diphosphatidylglycerol. Strain OG9-811 T contained Q-8 as a quinone. On the basis of polyphasic taxonomic characteristics, strain OG9-811 T is considered to represent a novel species, for which the name Vibrio ostreae sp. nov. is proposed. The type strain is OG9-811 T (=KCTC 72623 T =GDMCC 1.2610 T ).