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6. SARS-CoV-2 Viral Shedding and Rapid Antigen Test Performance--Respiratory Virus Transmission Network, November 2022-May 2023

Author

Smith-Jeffcoat, Sarah E., Mellis, Alexandra M., Grijalva, Carlos G., Talbot, H. Keipp, Schmitz, Jonathan, Lutrick, Karen, Ellingson, Katherine D., Stockwell, Melissa S., McLaren, Son H., Nguyen, Huong Q., Rao, Suchitra, Asturias, Edwin J., Davis-Gardner, Meredith E., Suthar, Mehul S., and Kirking, Hannah L.

Subjects
United States. Food and Drug Administration, Antigen-antibody reactions -- Comparative analysis -- Health aspects, Medical tests -- Comparative analysis -- Health aspects, Antiviral agents -- Health aspects -- Comparative analysis, Health care industry -- Comparative analysis -- Health aspects, Antigens -- Comparative analysis -- Health aspects, Infection -- Comparative analysis -- Health aspects, Health care industry, Health
Abstract

Introduction SARS-CoV-2 rapid antigen tests were developed and received Food and Drug Administration Emergency Use Authorization early during the COVID-19 pandemic. * These tests were initially rolled out broadly in [...]

Published
2024

9. Socioeconomic factors associated with uptake and satisfaction with a post‐hospitalization meals benefit in Medicare Advantage.

Author

Richards, Anna L., Vallejo, Jessica, Duan, Lewei, Dinsdale, Mary P., Akiyama‐Ciganek, Jaime, Arakelian, Annet, Lee, Janet S., Shen, Ernest, and Nguyen, Huong Q.

Subjects
CROSS-sectional method, SATISFACTION, DO-not-resuscitate orders, RESEARCH funding, SOCIOECONOMIC factors, HOSPITAL care, FOOD security, MEDICARE, QUESTIONNAIRES, PEOPLE of color, FOOD service, MULTIVARIATE analysis, DESCRIPTIVE statistics, SURVEYS, FINANCIAL stress, ELECTRONIC health records, MEALS, CONFIDENCE intervals, COMPARATIVE studies, DATA analysis software, LENGTH of stay in hospitals, REGRESSION analysis, DIET therapy, DIET in disease, OLD age
Abstract

Background: Kaiser Permanente Southern California began offering a 4‐week supplemental benefit of home‐delivered meals to Medicare Advantage members after discharge from a hospitalization for heart failure and other medical conditions in 2021. The purpose of this study is to explore the associations between socioeconomic disadvantage and food insecurity with patient uptake of and satisfaction with the meals. Methods: Data for this cross‐sectional study were drawn from survey and electronic medical record data for members referred for the meals benefit (n = 6169) and linked to a hospitalization encounter (n = 2254) between January and December 2021. Uptake was assessed using vendor records; measures of socioeconomic status included the neighborhood deprivation index (NDI) and prior receipt of medical financial assistance (MFA) from the health system. Patients were invited to complete an email or phone survey about their satisfaction with the meals and food insecurity. Multivariable log‐binomial regression models were used to examine the association between socioeconomic disadvantage and food insecurity with meals uptake and satisfaction. Results: Sixty‐two percent of patients referred for the benefit accepted the meals (mean age: 79 ± 9, 59% people of color). While there was no significant relationship between NDI and meals uptake (RR: 0.99, 95% CI: 0.92–1.07, p = 0.77), patients who received prior MFA were more likely to accept the meals (RR: 1.09, 95% CI: 1.02–1.16, p < 0.01). Sixty‐nine percent of patients who completed the survey (23% response rate) reported that meals were very or extremely helpful. Patients with food insecurity (29% of survey respondents) were more likely to report that the meals were helpful for their recovery compared to food secure patients (RR: 1.21, 95% CI: 1.09–1.35, p < 0.01). Conclusions: The home‐delivered meals appeared to be particularly utilized by and helpful to patients with greater financial strain and/or food insecurity, suggesting that supplemental benefits could be more targeted toward addressing unmet needs of vulnerable adults. See related Editorial by Amit Kumar. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Association Between Intensity and Timing of Specialty Palliative Care and Hospice Exposure With Quality of End-of-Life Care

Author

Wang, Susan E., primary, Gozansky, Wendolyn S., additional, Steiner, Claudia, additional, Lee, Janet S., additional, Nguyen, AnMarie, additional, Shen, Ernest, additional, Martel, Helene, additional, Mangels, Diana B., additional, Sterett, Andrew T., additional, Zalavadia, Ravi, additional, Hou, Nanjiang, additional, and Nguyen, Huong Q., additional

Published
2024
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11. Influenza virus shedding and symptoms: Dynamics and implications from a multi-season household transmission study

Author

Morris, Sinead E, primary, Nguyen, Huong Q, additional, Grijalva, Carlos G, additional, Hanson, Kayla E, additional, Zhu, Yuwei, additional, Biddle, Jessica E, additional, Meece, Jennifer K, additional, Halasa, Natasha B, additional, Chappell, James D, additional, Mellis, Alexandra M, additional, Reed, Carrie, additional, Biggerstaff, Matthew, additional, Belongia, Edward A, additional, Talbot, H Keipp, additional, and Rolfes, Melissa A, additional

Published
2024
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14. Long-term Neutralizing Antibody Levels Against Measles and Rubella Viruses Among Adults With 3 Doses of Measles-Mumps-Rubella Vaccine

Author

Alonge, Oluwakemi D, primary, Marin, Mona, additional, Hickman, Carole J, additional, Sowers, Sun B, additional, Chen, Min-hsin, additional, Hao, Lijuan, additional, Mercader, Sara, additional, El-Badry, Elina, additional, McClure, David L, additional, Icenogle, Joseph P, additional, Sugerman, David E, additional, Crooke, Stephen N, additional, and Nguyen, Huong Q, additional

Published
2024
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21. Clinically Diagnosing Pertussis-associated Cough in Adults and Children: CHEST Guideline and Expert Panel Report

Author

Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Bolser, Donald C., Birring, Surinder S., Blackwell, Fiona, Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Gibson, Peter, Gold, Philip, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Lown, Mark, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasoitis, Alex, Moore, Abigail, Murad, M. Hassan, Narasimhan, Mangala, Newcombe, Peter, Nguyen, Huong Q., Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Jaclyn, Smith, Maeve P., Tarlo, Susan M., Vertigan, Anne E., Weinberger, Miles, Grant, Cameron C., and Patel, Sheena

Published
2019
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22. Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza: CHEST Guideline and Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Cowley, Terrie, Davenport, Paul, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Gibson, Peter, Gold, Philip, Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Madison, J. Mark, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Molasoitis, Alex, Moore, Abigail, Murad, M. Hassan, Narasimhan, Mangala, Newcombe, Peter, Nguyen, Huong Q., Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Russell, Richard J., Ryu, Jay H., Singh, Sonal, Smith, Jaclyn, Smith, Maeve P., Tarlo, Susan M., Turmel, Julie, Vertigan, Anne E., Wang, Gang, Weinberger, Miles, Gold, Philip M., Metlay, Joshua P., and Ireland, Belinda

Published
2019
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27. Recreational physical activity in postmenopausal women is stable over 8 years of follow-up.

Author

Nguyen, Huong Q, Herting, Jerald R, Kohen, Ruth, Perry, Cynthia K, LaCroix, Andrea, Adams-Campbell, Lucile Lauren, Beresford, Shirley AA, Eaton, Charles B, and Tinker, Lesley

Subjects
Public Health, Health Sciences, Behavioral and Social Science, Basic Behavioral and Social Science, Prevention, Mind and Body, Aged, Exercise, Female, Follow-Up Studies, Health Behavior, Health Status, Humans, Life Style, Mental Health, Middle Aged, Postmenopause, Recreation, Socioeconomic Factors, Time Factors, Human Movement and Sports Sciences, Public Health and Health Services, Curriculum and Pedagogy, Allied health and rehabilitation science, Public health, Sports science and exercise
Abstract

BackgroundThe goals of this study were to examine 1) longitudinal trajectories of energy expenditure from recreational physical activity (PA) in postmenopausal women, 2) whether women who belong to different PA trajectories engage in different types of PA, and 3) whether baseline sociodemographic, health, psychosocial, and lifestyle characteristics predict membership in PA trajectories.MethodsWomen from the Women's Health Initiative Observational Study with baseline PA data (n = 92,629) were included. Physical activity, measured via self-report 6 times over 8 years, was converted to MET hr/wk for analysis. Latent growth curve mixture models and latent profile models were used to analyze longitudinal PA trajectories and cross-sectional PA composition, respectively.ResultsThree distinct, stable PA trajectories (highly, moderately, and minimally active) were identified with nearly 75% of the women classified as minimally active (≤ 8 MET-hr/wk). The majority of women who were at least moderately active engaged in a balanced combination of walking, moderate, and vigorous PA. Sociodemographic characteristics such as income, education, and past vigorous PA were predictive of PA trajectory, as were some health status indicators (eg, body mass index), but not health related quality of life.ConclusionsSelf-reported PA is largely stable across nearly a decade of follow-up in postmenopausal women.

Published
2013

28. Does neighborhood walkability moderate the effects of intrapersonal characteristics on amount of walking in post-menopausal women?

Author

Perry, Cynthia K, Herting, Jerald R, Berke, Ethan M, Nguyen, Huong Q, Moudon, Anne Vernez, Beresford, Shirley AA, Ockene, Judith K, Manson, JoAnn E, and LaCroix, Andrea Z

Subjects
Human Geography, Public Health, Health Sciences, Human Society, Aging, Clinical Research, Contraception/Reproduction, Age Factors, Educational Status, Environment Design, Exercise, Female, Health Status, Humans, Middle Aged, Racial Groups, Residence Characteristics, Walking, Washington, Continental Population Groups, Public Health and Health Services, Health sciences, Human society
Abstract

This study identifies factors associated with walking among postmenopausal women and tests whether neighborhood walkability moderates the influence of intrapersonal factors on walking. We used data from the Women's Health Initiative Seattle Center and linear regression models to estimate associations and interactions. Being white and healthy, having a high school education or beyond and greater non-walking exercise were significantly associated with more walking. Neighborhood walkability was not independently associated with greater walking, nor did it moderate influence of intrapersonal factors on walking. Specifying types of walking (e.g., for transportation) can elucidate the relationships among intrapersonal factors, the built environment, and walking.

Published
2013

35. Inflammatory Markers and Fatigue in Individuals With Moderate to Severe Chronic Obstructive Pulmonary Disease.

Author

Jung Eun Lee, Nguyen, Huong Q., and Fan, Vincent S.

Subjects
*BIOMARKERS, *C-reactive protein, *INTERLEUKINS, *SOCIAL support, *PAIN, *SCIENTIFIC observation, *CONFIDENCE intervals, *CROSS-sectional method, *MULTIVARIATE analysis, *REGRESSION analysis, *MULTIDIMENSIONAL scaling, *OBSTRUCTIVE lung diseases, *MENTAL depression, *FATIGUE (Physiology), *ANXIETY, *SOCIODEMOGRAPHIC factors, *LONGITUDINAL method, *DISEASE complications
Abstract

Background: Fatigue, a prevalent complex symptom among patients with chronic obstructive pulmonary disease (COPD), is considered an important clinical indicator of disease severity. However, the underlying mechanisms of COPD-related fatigue are not fully understood. Objectives: This analysis explored the relationships between peripheral inflammatory markers and COPD-related fatigue in people with moderate to severe COPD. Methods: This is a secondary analysis of a longitudinal observational study of individuals with COPD examining the biological causes and functional consequences of depression. The data used in this study were collected at baseline. Systemic inflammation markers included C-reactive protein (CRP) and three pro-inflammatory cytokines consisting of interleukin-6 (IL-6), IL-8, and tumor necrosis factor-a. COPD-related fatigue was self-reported using the Chronic Respiratory Questionnaire. Covariates included age; gender; smoking status; disease severity; symptoms of depression, anxiety, and pain; and social support. Multivariable linear regression analyses were conducted. Results: The sample included 300 adults living with COPD; 80% were male, and the average age was 67.6 years. Modest correlations were found between two systemic inflammatorymarkers (CRP and IL-8) and COPD-related fatigue. CRP was the only inflammatory marker significantly associated with fatigue symptoms after adjusting for covariates in multivariable analyses. Depression, pain, and education level were also significant predictors of COPD-related fatigue. Discussion: The findings suggest that altered immune response based on CRP may contribute to COPD-related fatigue. Management of depression and pain may work as an effective treatment strategy for COPD-related fatigue. Further longitudinal studies with a broader range of inflammatory markers and multidimensional measures of fatigue symptoms are warranted. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Chronic Cough Due to Gastroesophageal Reflux in Adults: CHEST Guideline and Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Blackhall, Fiona, Bolser, Donald C., Boulet, Louis-Philippe, Brightling, Christopher, Callahan-Lyon, Priscilla, Canning, Brendan J., Chang, Anne B., Cowley, Terrie, Ebihara, Satoru, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Feinstein, Anthony, Fisher, Dina, French, Cynthia T., Gibson, Peter, Gold, Philip, Gould, Michael K., Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Malesker, Mark A., Mazzone, Stuart, McGarvey, Lorcan, Murad, M. Hassan, Nguyen, Huong Q., Newcombe, Peter, Oppenheimer, John, Rosen, Mark, Rubin, Bruce, Ryu, Jay H., Smith, Jaclyn, Tarlo, Susan M., Vertigan, Anne E., Wang, Gang, Weinberger, Miles, and Weir, Kelly

Published
2016
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40. Tools for Assessing Outcomes in Studies of Chronic Cough: CHEST Guideline and Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne Bernadette, Coeytaux, Remy, Cowley, Terrie, Davenport, Paul, Diekemper, Rebecca L., Ebihara, Satoru, El Solh, Ali A., Escalante, Patricio, Feinstein, Anthony, Field, Stephen K., Fisher, Dina, French, Cynthia T., Gibson, Peter, Gold, Philip, Gould, Michael K., Grant, Cameron, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Keogh, Karina A., Lane, Andrew P., Lewis, Sandra Zelman, Lim, Kaiser, Malesker, Mark A., Mazzone, Stuart, McCrory, Douglas C., McGarvey, Lorcan, Molasiotis, Alex, Murad, M. Hassan, Newcombe, Peter, Nguyen, Huong Q., Oppenheimer, John, Prezant, David, Restrepo, Marcos I., Rosen, Mark, Rubin, Bruce, Ryu, Jay H., Smith, Jaclyn, Tarlo, Susan M., Vertigan, Anne, Wang, Gang, Weinberger, Miles, Weir, Kelly, Coeytaux, Remy R., and Chang, Anne B.

Published
2015
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44. Methodologies for the Development of the Management of Cough: CHEST Guideline and Expert Panel Report

Author

Adams, Todd M., Altman, Kenneth W., Barker, Alan F., Birring, Surinder S., Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Canning, Brendan, Chang, Anne Bernadette, Coeytaux, Remy, Cowley, Terrie, Davenport, Paul, Diekemper, Rebecca L., Ebihara, Satoru, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Gibson, Peter, Gold, Philip, Gould, Michael K., Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Keogh, Karina A., Lane, Andrew P., Lewis, Sandra Zelman, Lim, Kaiser, Malesker, Mark A., Mazzone, Peter, McCrory, Douglas C., McGarvey, Lorcan, Murad, M. Hassan, Newcombe, Peter, Nguyen, Huong Q., Oppenheimer, John, Prezant, David, Pringsheim, Tamara, Restrepo, Marcos I., Rosen, Mark, Rubin, Bruce, Ryu, Jay H., Smith, Jaclyn, Tarlo, Susan M., Turner, Ronald B., Vertigan, Anne, Weir, Kelly, Wiener, Renda Soylemez, Diekemper, Rebecca L, French, Cynthia T, Gold, Philip M, and Irwin, Richard S

Published
2014
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47. Classification of Cough as a Symptom in Adults and Management Algorithms: CHEST Guideline and Expert Panel Report

Author

Irwin, Richard S., French, Cynthia L., Chang, Anne B., Altman, Kenneth W., Adams, Todd M., Azoulay, Elie, Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Boulet, Louis-Philippe, Brightling, Christopher, Callahan-Lyon, Priscilla, Cowley, Terrie, Ebihara, Satoru, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Gibson, Peter, Gold, Philip, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Madison, Mark J., Malesker, Mark A., Mazzone, Stuart, Molassoitis, Alex, Murad, Hassan M., Narasimhan, Mangala, Nguyen, Huong Q., Newcombe, Peter, Oppenheimer, John, Restrepo, Marcos I., Rosen, Mark, Rubin, Bruce, Ryu, Jay H., Tarlo, Susan M., Turmel, Julie, Vertigan, Anne E., Wang, Gang, and Weinberger, Miles

Published
2018
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49. Cough in Ambulatory Immunocompromised Adults: CHEST Expert Panel Report

Author

Rosen, Mark J., Ireland, Belinda, Narasimhan, Mangala, French, Cynthia, Irwin, Richard S., Adams, Todd M., Altman, Kenneth W., Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Braman, Sidney S., Brightling, Christopher, Callahan-Lyon, Priscilla, Chang, Anne B., Coté, Andréanne, Cowley, Terrie, Davenport, Paul, Ebihara, Satoru, El Solh, Ali A., Escalante, Patricio, Feinstein, Anthony, Field, Stephen K., Fisher, Dina, French, Cynthia T., Gibson, Peter, Gold, Philip, Harnden, Anthony, Hill, Adam T., Kahrilas, Peter J., Keogh, Karina A., Lai, Kefang, Lim, Kaiser, Madison, Mark J., Malesker, Mark A., Mazzone, Stuart, Molassoitis, Alex, Murad, Hassan M., Nguyen, Huong Q., Newcombe, Peter, Oppenheimer, John J., Restrepo, Marcos I., Rosen, Mark, Rubin, Bruce, Ryu, Jay H., Smith, Jaclyn, Tarlo, Susan M., Turmel, Julie, Vertigan, Anne E., Wang, Gang, Weinberger, Miles, and Weir, Kelly

Published
2017
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50. Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold: CHEST Expert Panel Report

Author

Malesker, Mark A., Callahan-Lyon, Priscilla, Ireland, Belinda, Irwin, Richard S., Adams, Todd M., Altman, Kenneth W., Azoulay, Elie, Barker, Alan F., Birring, Surinder S., Blackhall, Fiona, Bolser, Donald C., Boulet, Louis-Philippe, Braman, Sidney S., Brightling, Christopher, Chang, Anne B., Coté, Andréanne, Cowley, Terrie, Davenport, Paul, Ebihara, Satoru, El Solh, Ali A., Escalante, Patricio, Field, Stephen K., Fisher, Dina, French, Cynthia T., Grant, Cameron, Gibson, Peter, Gold, Philip, Harding, Susan M., Harnden, Anthony, Hill, Adam T., Irwin, Richard S., Kahrilas, Peter J., Kavanagh, Joanne, Keogh, Karina A., Lai, Kefang, Lane, Andrew P., Lim, Kaiser, Madison, Mark J., Mazzone, Stuart, McGarvey, Lorcan, Molassoitis, Alex, Murad, Hassan M., Narasimhan, Mangala, Newcombe, Peter, Nguyen, Huong Q., Oppenheimer, John, Restrepo, Marcos I., Rosen, Mark, Rubin, Bruce, Ryu, Jay H., Smith, Jaclyn, Tarlo, Susan M., Turmel, Julie, Vertigan, Anne E., Wang, Gang, Weinberger, Miles, and Weir, Kelly

Published
2017
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