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7. Heart failure, the global pandemic: A call to action consensus statement from the global presidential conclave at the platinum jubilee conference of cardiological society of India 2023

Author

Harikrishnan, Sivadasanpillai, Rath, Prathap Chandra, Bang, Vijay, McDonagh, Theresa, Ogola, Elijah, Silva, Hugo, Rajbanshi, Bijoy G., Pathirana, Anidu, Ng, G. Andre, Biga, Cathleen, Lüscher, Thomas F., Daggubati, Ramesh, Adivi, Shirley, Roy, Debabrata, Banerjee, P.S., and Das, M.K.

Published
2024
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14. Larval dispersal in a changing ocean with an emphasis on upwelling regions

Author

Bashevkin, SM, Dibble, CD, Dunn, RP, Hollarsmith, JA, Ng, G, Satterthwaite, EV, and Morgan, SG

Subjects
Ecological Applications, Ecology, Zoology
Abstract

Dispersal of benthic species in the sea is mediated primarily through small, vulnerable larvae that must survive minutes to months as members of the plankton community while being transported by strong, dynamic currents. As climate change alters ocean conditions, the dispersal of these larvae will be affected, with pervasive ecological and evolutionary consequences. We review the impacts of oceanic changes on larval transport, physiology, and behavior. We then discuss the implications for population connectivity and recruitment and evaluate life history strategies that will affect susceptibility to the effects of climate change on their dispersal patterns, with implications for understanding selective regimes in a future ocean. We find that physical oceanographic changes will impact dispersal by transporting larvae in different directions or inhibiting their movements while changing environmental factors, such as temperature, pH, salinity, oxygen, ultraviolet radiation, and turbidity, will affect the survival of larvae and alter their behavior. Reduced dispersal distance may make local adaptation more likely in well-connected populations with high genetic variation while reduced dispersal success will lower recruitment with implications for fishery stocks. Increased dispersal may spur adaptation by increasing genetic diversity among previously disconnected populations as well as increasing the likelihood of range expansions. We hypothesize that species with planktotrophic (feeding), calcifying, or weakly swimming larvae with specialized adult habitats will be most affected by climate change. We also propose that the adaptive value of retentive larval behaviors may decrease where transport trajectories follow changing climate envelopes and increase where transport trajectories drive larvae toward increasingly unsuitable conditions. Our holistic framework, combined with knowledge of regional ocean conditions and larval traits, can be used to produce powerful predictions of expected impacts on larval dispersal as well as the consequences for connectivity, range expansion, or recruitment. Based on our findings, we recommend that future studies take a holistic view of dispersal incorporating biological and oceanographic impacts of climate change rather than solely focusing on oceanography or physiology. Genetic and paleontological techniques can be used to examine evolutionary impacts of altered dispersal in a future ocean, while museum collections and expedition records can inform modern-day range shifts.

Published
2020

15. Different paths, same destination: divergent action potential responses produce conserved cardiac fight‐or‐flight response in mouse and rabbit hearts

Author

Wang, Lianguo, Morotti, Stefano, Tapa, Srinivas, Stuart, Samantha D Francis, Jiang, Yanyan, Wang, Zhen, Myles, Rachel C, Brack, Kieran E, Ng, G André, Bers, Donald M, Grandi, Eleonora, and Ripplinger, Crystal M

Subjects
Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Neurosciences, Heart Disease, Action Potentials, Animals, Calcium Signaling, Heart, Heart Rate, Male, Mice, Mice, Inbred C57BL, Models, Cardiovascular, Myocardial Contraction, Rabbits, Stress, Physiological, Sympathetic Nervous System, Optical mapping, sympathetic activation, intracellular Ca2+, action potential, mathematical modelling, Biological Sciences, Medical and Health Sciences, Physiology, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract

Key pointsCardiac electrophysiology and Ca2+ handling change rapidly during the fight-or-flight response to meet physiological demands. Despite dramatic differences in cardiac electrophysiology, the cardiac fight-or-flight response is highly conserved across species. In this study, we performed physiological sympathetic nerve stimulation (SNS) while optically mapping cardiac action potentials and intracellular Ca2+ transients in innervated mouse and rabbit hearts. Despite similar heart rate and Ca2+ handling responses between mouse and rabbit hearts, we found notable species differences in spatio-temporal repolarization dynamics during SNS. Species-specific computational models revealed that these electrophysiological differences allowed for enhanced Ca2+ handling (i.e. enhanced inotropy) in each species, suggesting that electrophysiological responses are fine-tuned across species to produce optimal cardiac fight-or-flight responses.AbstractSympathetic activation of the heart results in positive chronotropy and inotropy, which together rapidly increase cardiac output. The precise mechanisms that produce the electrophysiological and Ca2+ handling changes underlying chronotropic and inotropic responses have been studied in detail in isolated cardiac myocytes. However, few studies have examined the dynamic effects of physiological sympathetic nerve activation on cardiac action potentials (APs) and intracellular Ca2+ transients (CaTs) in the intact heart. Here, we performed bilateral sympathetic nerve stimulation (SNS) in fully innervated, Langendorff-perfused rabbit and mouse hearts. Dual optical mapping with voltage- and Ca2+ -sensitive dyes allowed for analysis of spatio-temporal AP and CaT dynamics. The rabbit heart responded to SNS with a monotonic increase in heart rate (HR), monotonic decreases in AP and CaT duration (APD, CaTD), and a monotonic increase in CaT amplitude. The mouse heart had similar HR and CaT responses; however, a pronounced biphasic APD response occurred, with initial prolongation (50.9 ± 5.1 ms at t = 0 s vs. 60.6 ± 4.1 ms at t = 15 s, P

Published
2019

17. Improved measurements of two-photon widths of the $\chi_{cJ}$ states and helicity analysis for $\chi_{c2}\to\gamma\gamma$

Author

BESIII Collaboration, Ablikim, M., Achasov, M. N., Ahmed, S., Albrecht, M., Amoroso, A., An, F. F., An, Q., Bai, J. Z., Bai, Y., Bakina, O., Ferroli, R. Baldini, Ban, Y., Bennett, D. W., Bennett, J. V., Berger, N., Bertani, M., Betton i, D., Bian, J. M., Bianchi, F., Boger, E., Boyko, I., Briere, R. A., Cai, H., Cai, X., Cakir, O., Calcaterra, A., Cao, G. F., Cetin, S. A., Chai, J., Chang, J. F., Chelkov, G., Chen, G., Chen, H. S., Chen, J. C., Chen, M. L., Chen, S. J., Chen, X. R., Chen, Y. B., Chu, X. K., Cibinetto, G., Dai, H. L., Dai, J. P., Dbeyssi, A., Dedovich, D., Deng, Z. Y., Denig, A., Denysenko, I., Destefanis, M., De Mori, F., Ding, Y., Dong, C., ng, J. Do, Dong, L. Y., Dong, M. Y., Dorjkhaidav, O., Dou, Z. L., Du, S. X., Duan, P. F., Fang, J., Fang, S. S., Fang, X., Fang, Y., Farinelli, R., Fava, L., Fegan, S., Feldbauer, F., Felici, G., Feng, C. Q., Fioravanti, E., Fritsch, M., Fu, C. D., Gao, Q., Gao, X. L., Gao, Y., Gao, Y. G., Gao, Z., Garzia, I., Goetzen, K., Gong, L., Gong, W. X., Gradl, W., Greco, M., Gu, M. H., Gu, S., Gu, Y. T., Guo, A. Q., Guo, L. B., Guo, R. P., Guo, Y. P., Haddadi, Z., Han, S., Hao, X. Q., Harris, F. A., He, K. L., He, X. Q., Heinsius, F. H., Held, T., Heng, Y. K., Holtmann, T., Hou, Z. L., Hu, C., Hu, H. M., Hu, T., Hu, Y., Huang, G. S., Huang, J. S., Huang, X. T., Huang, X. Z., Huang, Z. L., Hussain, T., Andersson, W. Ikegami, Ji, Q., Ji, Q. P., Ji, X. B., Ji, X. L., Jiang, X. S., Jiang, X. Y., Jiao, J. B., Jiao, Z., Jin, D. P., Jin, S., Jin, Y., Johansson, T., Julin, A., alantar-Nayestanaki, N. K, Kang, X. L., Kang, X. S., Kavatsyuk, M., Ke, B. C., Khan, T., Khoukaz, A., Kiese, P., Kliemt, R., Koch, L., Kolcu, O. B., Kopf, B., Kornicer, M., Kuemmel, M., Kuhlmann, M., Kupsc, A., Kühn, W., Lange, J. S., Lara, M., Larin, P., Lavezzi, L., Leithoff, H., Leng, C., Li, C., Li, Cheng, Li, D. M., Li, F., Li, F. Y., Li, G., Li, H. B., Li, H. J., Li, J. C., Li, Jin, Li, K., Li, K. J., Li, Lei, Li, P. L., Li, P. R., Li, Q. Y., Li, T., Li, W. D., Li, W. G., Li, X. L., Li, X. N., Li, X. Q., Li, Z. B., Liang, H., Liang, Y. F., Liang, Y. T., Liao, G. R., Lin, D. X., Liu, B., Liu, B. J., Liu, C. X., Liu, D., Liu, F. H., Liu, Fang, Liu, Feng, Liu, H. B., Liu, H. H., Liu, H. M., Liu, J. B., Liu, J. P., Liu, J. Y., Liu, K., Liu, K. Y., Liu, Ke, Liu, L. D., Liu, P. L., Liu, Q., Liu, S. B., Liu, X., Liu, Y. B., Liu, Y. Y., Liu, Z. A., Liu, Zhiqing, Long, Y. F., Lou, X. C., Lu, H. J., Lu, J. G., Lu, Y., Lu, Y. P., Luo, C. L., Luo, M. X., Luo, X. L., Lyu, X. R., Ma, F. C., Ma, H. L., Ma, L. L., Ma, M. M., Ma, Q. M., Ma, T., Ma, X. N., Ma, X. Y., Ma, Y. M., Maas, F. E., Maggiora, M., Malik, Q. A., Mao, Y. J., Mao, Z. P., Marcello, S., Meng, Z. X., Messchendorp, J. G., Mezzadri, G., Min, J., Min, T. J., Mitchell, R. E., Mo, X. H., Mo, Y. J., Morales, C. Morales, Morello, G., Muchnoi, N. Yu., Muramatsu, H., Musiol, P., Mustafa, A., Nefedov, Y., Nerling, F., Nikolaev, I. B., Ning, Z., Nisar, S., Niu, S. L., Niu, X. Y., Olsen, S. L., Ouyang, Q., Pacetti, S., Pan, Y., Patter i, P., Pelizaeus, M., Pellegrino, J., Peng, H. P., Peters, K., Pettersson, J., Ping, J. L., Ping, R. G., Poling, R., Prasad, V., Qi, H. R., Qi, M., Qian, S., Qiao, C. F., Qin, J. J., Qin, N., Qin, X. S., Qin, Z. H., Qiu, J. F., Rashid, K. H., Redmer, C. F., Richter, M., Ripka, M., Rolo, M., Rong, G., Rosner, Ch., Ruan, X. D., Sarantsev, A., Savrié, M., Schnier, C., Schoenning, K., Shan, W., Shao, M., Shen, C. P., Shen, P. X., Shen, X. Y., Sheng, H. Y., Song, J. J., Song, X. Y., Sosio, S., Sowa, C., Spataro, S., Sun, G. X., Sun, J. F., Sun, L., Sun, S. S., Sun, X. H., Sun, Y. J., Sun, Y. K, Sun, Y. Z., Sun, Z. J., Sun, Z. T., Tang, C. J., ng, G. Y. Ta, Tang, X., Tapan, I., Tiemens, M., Tsednee, B. T., Uman, I., Varner, G. S., Wang, B., Wang, B. L., Wang, D., Wang, D. Y., Wang, Dan, Wang, K., Wang, L. L., Wang, L. S., Wang, M., Wang, P., Wang, P. L., Wang, W. P., Wang, X. F., Wang, Y. D., Wang, Y. F., Wang, Y. Q., Wang, Z., Wang, Z. G., Wang, Z. H., Wang, Z. Y., Weber, T., Wei, D. H., Weidenkaff, P., Wen, S. P., Wiedner, U., Wolke, M., Wu, L. H., Wu, L. J., Wu, Z., Xia, L., Xia, Y., Xiao, D., Xiao, H., Xiao, Y. J., Xiao, Z. J., Xie, Y. G., Xie, Y. H., Xiong, X. A., Xiu, Q. L., Xu, G. F., Xu, J. J., Xu, L., Xu, Q. J., Xu, Q. N., Xu, X. P., Yan, L., Yan, W. B., Yan, W. C., an, Y. H. Y, Yang, H. J., Yang, H. X., Yang, L., Yang, Y. H., Yang, Y. X., Ye, M., Ye, M. H., Yin, J. H., You, Z. Y., Yu, B. X., Yu, C. X., Yu, J. S., Yuan, C. Z., Yuan, Y., Yuncu, A., Zafar, A. A., Zeng, Y., Zeng, Z., ang, B. X. Zh, Zhang, B. Y., Zhang, C. C., Zhang, D. H., Zhang, H. H., Zhang, H. Y., Zhang, J., Zhang, J. L., Zhang, J. Q., Zhang, J. W., Zhang, J. Y., Zhang, J. Z., Zhang, K., Zhang, L., Zhang, S. Q., Zhang, X. Y., Zhang, Y., Zhang, Y. H., Zhang, Y. T., Zhang, Yu, Zhang, Z. H., Zhang, Z. P., Zhang, Z. Y., Zhao, G., Zhao, J. W., Zhao, J. Y., Zhao, J. Z., Zhao, Lei, Zhao, Ling, Zhao, M. G., Zhao, Q., Zhao, S. J., Zhao, T. C., Zhao, Y. B., Zhao, Z. G., Zhemchugov, A., Zheng, B., Zheng, J. P., Zheng, W. J., Zheng, Y. H., Zhong, B., Zhou, L., Zhou, X., Zhou, X. K., Zhou, X. R., Zhou, X. Y., Zhou, Y. X., Zhu, J., Zhu, K., Zhu, K. J., Zhu, S., Zhu, S. H., Zhu, X. L., Zhu, Y. C., Zhu, Y. S., Zhu, Z. A., Zhuang, J., Zotti, L., Zou, B. S., and Zou, J. H.

Subjects
High Energy Physics - Experiment
Abstract

Based on $448.1 \times 10^6$ $\psi(3686)$ events collected with the BESIII detector, the decays $\psi(3686)\to\gamma\chi_{cJ}, \chi_{cJ} \to \gamma\gamma~(J=0, 1, 2)$ are studied. The decay branching fractions of $\chi_{c0,c2} \to \gamma\gamma$ are measured to be $\mathcal{B}(\chi_{c0}\to\gamma\gamma) = (1.93 \pm 0.08 \pm 0.05 \pm 0.05)\times 10^{-4}$ and $\mathcal{B}(\chi_{c2}\to\gamma\gamma) = (3.10 \pm 0.09 \pm 0.07 \pm 0.11)\times 10^{-4} $, which correspond to two-photon decay widths of $\Gamma_{\gamma\gamma}(\chi_{c0}) = 2.03 \pm 0.08 \pm 0.06 \pm 0.13 ~\rm{keV}$ and $\Gamma_{\gamma\gamma}(\chi_{c2}) = 0.60 \pm 0.02 \pm 0.01 \pm 0.04 ~\rm{keV}$ with a ratio of $\mathcal{R}=\Gamma_{\gamma\gamma}(\chi_{c2})/\Gamma_{\gamma\gamma}(\chi_{c0})= 0.295 \pm 0.014 \pm 0.007 \pm 0.027$, where the uncertainties are statistical, systematic and associated with the uncertainties of $\mathcal{B}(\psi(3686)\to\gamma\chi_{c0,c2})$ and the total widths $\Gamma(\chi_{c0,c2})$, respectively. For the forbidden decay of $\chi_{c1}\to\gamma\gamma$, no signal is observed, and an upper limit on the two-photon width is obtained to be $\Gamma_{\gamma\gamma}(\chi_{c1})<5.3 ~\rm{eV}$ at the 90\% confidence level. The ratio of the two-photon widths between helicity-zero and helicity-two components in the decay $\chi_{c2}\to\gamma\gamma$ is also measured to be $f_{0/2} = \Gamma^{\lambda=0}_{\gamma\gamma}(\chi_{c2})/\Gamma^{\lambda=2}_{\gamma\gamma}(\chi_{c2}) = (0.0 \pm 0.6 \pm 1.2)\times 10^{-2}$, where the uncertainties are statistical and systematic, respectively., Comment: 11 pages, 4 figures, 4 tables

Published
2017
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18. All-sky Search for Periodic Gravitational Waves in the O1 LIGO Data

Author

LIGO Scientific Collaboration, Virgo Collaboration, Abbott, B. P., Abbott, R., Abbott, T. D., Acernese, F., Ackley, K., Adams, C., Adams, T., Addesso, P., Adhikari, R. X., Adya, V. B., Affeldt, C., Afrough, M., Agarwal, B., Agatsuma, K., Aggarwal, N., Aguiar, O. D., Aiello, L., Ain, A., Ajith, P., Allen, B., Allen, G., Allocca, A., Altin, P. A., Amato, A., Ananyeva, A., Anderson, S. B., Anderson, W. G., Antier, S., Appert, S., Arai, K., Araya, M. C., Areeda, J. S., Arnaud, N., Ascenzi, S., Ashton, G., Ast, M., Aston, S. M., Astone, P., Aufmuth, P., Aulbert, C., AultONeal, K., Avila-Alvarez, A., Babak, S., Bacon, P., Bader, M. K. M., Bae, S., Baker, P. T., Baldaccini, F., Ballardin, G., Ballmer, S. W., Banagiri, S., Barayoga, J. C., Barclay, S. E., Barish, B. C., Barker, D., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartlett, J., Bartos, I., Bassiri, R., Basti, A., Batch, J. C., Baune, C., Bawaj, M., Bazzan, M., Bécsy, B., Beer, C., Bejger, M., Belahcene, I., Bell, A. S., Berger, B. K., Bergmann, G., Berry, C. P. L., Bersanetti, D., Bertolini, A., Betzwieser, J., Bhagwat, S., Bhandare, R., Bilenko, I. A., Billingsley, G., Billman, C. R., Birch, J., Birney, R., Birnholtz, O., Biscans, S., Bisht, A., Bitossi, M., Biwer, C., Bizouard, M. A., Blackburn, J. K., Blackman, J., Blair, C. D., Blair, D. G., Blair, R. M., Bloemen, S., Bock, O., Bode, N., Boer, M., Bogaert, G., Bohe, A., Bondu, F., Bonnand, R., Boom, B. A., Bork, R., Boschi, V., Bose, S., Bouffanais, Y., Bozzi, A., Bradaschia, C., Brady, P. R., Branchesi, V. B. Braginsky M., Brau, J. E., Briant, T., Brillet, A., Brinkmann, M., Brisson, V., Brockill, P., Broida, J. E., Brooks, A. F., Brown, D. A., Brown, D. D., Brown, N. M., Brunett, S., Buchanan, C. C., Buikema, A., Bulik, T., Bulten, H. J., Buonanno, A., Buskulic, D., Buy, C., Byer, R. L., Cabero, M., Cadonati, L., Cagnoli, G., Cahillane, C., Bustillo, J. Calderón, Callister, T. A., Calloni, E., Camp, J. B., Canizares, P., Cannon, K. C., Cao, H., Cao, J., Capano, C. D., Capocasa, E., Carbognani, F., Caride, S., Carney, M. F., Diaz, J. Casanueva, Casentini, C., Caudill, S., Cavaglià, M., Cavalier, F., Cavalieri, R., Cella, G., Cepeda, C. B., Baiardi, L. Cerboni, Cerretani, G., Cesarini, E., Chamberlin, S. J., Chan, M., Chao, S., Charlton, P., Chassande-Mottin, E., Chatterjee, D., Cheeseboro, B. D., Chen, H. Y., Chen, Y., Cheng, H. -P., Chincarini, A., Chiummo, A., Chmiel, T., Cho, H. S., Cho, M., Chow, J. H., Christensen, N., Chu, Q., Chua, A. J. K., Chua, S., Chung, A. K. W., Chung, S., Ciani, G., Ciecielag, P., Ciolfi, R., Cirelli, C. E., Cirone, A., Clara, F., Clark, J. A., Cleva, F., Cocchieri, C., Coccia, E., Cohadon, P. -F., Colla, A., Collette, C. G., Cominsky, L. R., Constancio Jr., M., Conti, L., Cooper, S. J., Corban, P., Corbitt, T. R., Corley, K. R., Cornish, N., Corsi, A., Cortese, S., Costa, C. A., Coughlin, E., Coughlin, M. W., Coughlin, S. B., Coulon, J. -P., Countryman, S. T., Couvares, P., Covas, P. B., Cowan, E. E., Coward, D. M., Cowart, M. J., Coyne, D. C., Coyne, R., Creighton, J. D. E., Creighton, T. D., Cripe, J., Crowder, S. G., Cullen, T. J., Cumming, A., Cunningham, L., Cuoco, E., Canton, T. Dal, Danilishin, S. L., D'Antonio, S., Danzmann, K., Dasgupta, A., Costa, C. F. Da Silva, Dattilo, V., Dave, I., Davier, M., Davis, D., Daw, E. J., Day, B., De, S., DeBra, D., Deelman, E., Degallaix, J., De Laurentis, M., Deléglise, S., Del Pozzo, W., Denker, T., Dent, T., Dergachev, V., De Rosa, R., DeRosa, R. T., DeSalvo, R., Devenson, J., Devine, R. C., Dhurandhar, S., Díaz, M. C., Di Fiore, L., Di Giovanni, M., Di Girolamo, T., Di Lieto, A., Di Pace, S., Di Palma, I., Di Renzo, F., Doctor, Z., Dolique, V., Donovan, F., Dooley, K. L., Doravari, S., Dorosh, O., Dorrington, I., Douglas, R., Álvarez, M. Dovale, Downes, T. P., Drago, M., Driggers, R. W. P. Drever J. C., Du, Z., Ducrot, M., Duncan, J., Dwyer, S. E., Edo, T. B., Edwards, M. C., Effler, A., Eggenstein, H. -B., Ehrens, P., Eichholz, J., Eikenberry, S. S., Eisenstein, R. A., Essick, R. C., Etienne, Z. B., Etzel, T., Evans, M., Evans, T. M., Factourovich, M., Fafone, V., Fair, H., Fairhurst, S., Fan, X., Farinon, S., Farr, B., Farr, W. M., Fauchon-Jones, E. J., Favata, M., Fays, M., Fehrmann, H., Feicht, J., Fejer, M. M., Fernandez-Galiana, A., Ferrante, I., Ferreira, E. C., Ferrini, F., Fidecaro, F., Fiori, I., Fiorucci, D., Fisher, R. P., Flaminio, R., Fletcher, M., Fong, H., Forsyth, P. W. F., Forsyth, S. S., Fournier, J. -D., Frasca, S., Frasconi, F., Frei, Z., Freise, A., Frey, R., Frey, V., Fries, E. M., Fritschel, P., Frolov, V. V., Fulda, P., Fyffe, M., Gabbard, H., Gabel, M., Gadre, B. U., Gaebel, S. M., Gair, J. R., Gammaitoni, L., Ganija, M. R., Gaonkar, S. G., Garufi, F., Gaudio, S., Gaur, G., Gayathri, V., Gemme, N. Gehrels G., Genin, E., Gennai, A., George, D., George, J., Gergely, L., Germain, V., Ghonge, S., Ghosh, Abhirup, Ghosh, Archisman, Ghosh, S., Giaime, J. A., Giardina, K. D., Giazotto, A., Gill, K., Glover, L., Goetz, E., Goetz, R., Gomes, S., González, G., Castro, J. M. Gonzalez, Gopakumar, A., Gorodetsky, M. L., Gossan, S. E., Gosselin, M., Gouaty, R., Grado, A., Graef, C., Granata, M., Grant, A., Gras, S., Gray, C., Greco, G., Green, A. C., Groot, P., Grote, H., Grunewald, S., Gruning, P., Guidi, G. M., Guo, X., Gupta, A., Gupta, M. K., Gushwa, K. E., Gustafson, E. K., Gustafson, R., Hall, B. R., Hall, E. D., Hammond, G., Haney, M., Hanke, M. M., Hanks, J., Hanna, C., Hannuksela, O. A., Hanson, J., Hardwick, T., Harms, J., Harry, G. M., Harry, I. W., Hart, M. J., Haster, C. -J., Haughian, K., Healy, J., Heidmann, A., Heintze, M. C., Heitmann, H., Hello, P., Hemming, G., Hendry, M., Heng, I. S., Hennig, J., Henry, J., Heptonstall, A. W., Heurs, M., Hild, S., Hoak, D., Hofman, D., Holt, K., Holz, D. E., Hopkins, P., Horst, C., Hough, J., Houston, E. A., Howell, E. J., Hu, Y. M., Huerta, E. A., Huet, D., Hughey, B., Husa, S., Huttner, S. H., Huynh-Dinh, T., Indik, N., Ingram, D. R., Inta, R., Intini, G., Isa, H. N., Isac, J. -M., Isi, M., Iyer, B. R., Izumi, K., Jacqmin, T., Jani, K., Jaranowski, P., Jawahar, S., Jiménez-Forteza, F., Johnson, W. W., Jones, D. I., Jones, R., Jonker, R. J. G., Ju, L., Junker, J., Kalaghatgi, C. V., Kalogera, V., Kandhasamy, S., Kang, G., Kanner, J. B., Karki, S., Karvinen, K. S., Kasprzack, M., Katolik, M., Katsavounidis, E., Katzman, W., Kaufer, S., Kawabe, K., Kéfélian, F., Keitel, D., Kemball, A. J., Kennedy, R., Kent, C., Key, J. S., Khalili, F. Y., Khan, I., Khan, S., Khan, Z., Khazanov, E. A., Kijbunchoo, N., Kim, Chunglee, Kim, J. C., Kim, W., Kim, W. S., Kim, Y. -M., Kimbrell, S. J., King, E. J., King, P. J., Kirchhoff, R., Kissel, J. S., Kleybolte, L., Klimenko, S., Koch, P., Koehlenbeck, S. M., Koley, S., Kondrashov, V., Kontos, A., Korobko, M., Korth, W. Z., Kowalska, I., Kozak, D. B., Krämer, C., Kringel, V., Krishnan, B., Królak, A., Kuehn, G., Kumar, P., Kumar, R., Kumar, S., Kuo, L., Kutynia, A., Kwang, S., Lackey, B. D., Lai, K. H., Landry, M., Lang, R. N., Lange, J., Lantz, B., Lanza, R. K., Lartaux-Vollard, A., Lasky, P. D., Laxen, M., Lazzarini, A., Lazzaro, C., Leaci, P., Leavey, S., Lee, C. H., Lee, H. K., Lee, H. M., Lee, H. W., Lee, K., Lehmann, J., Lenon, A., Leonardi, M., Leroy, N., Letendre, N., Levin, Y., Li, T. G. F., Libson, A., Littenberg, T. B., Liu, J., Liu, W., Lo, R. K. L., Lockerbie, N. A., London, L. T., Lord, J. E., Lorenzini, M., Loriette, V., Lormand, M., Losurdo, G., Lough, J. D., Lovelace, G., Lück, H., Lumaca, D., Lundgren, A. P., Lynch, R., Ma, Y., Macfoy, S., Machenschalk, B., MacInnis, M., Macleod, D. M., Hernandez, I. Magaña, Magaña-Sandoval, F., Zertuche, L. Magaña, Magee, R. 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E., Wade, M., Walet, R., Walker, M., Wallace, L., Walsh, S., Wang, G., Wang, H., Wang, J. Z., Wang, M., Wang, Y. -F., Wang, Y., Ward, R. L., Warner, J., Was, M., Watchi, J., Weaver, B., Wei, L. -W., Weinert, M., Weinstein, A. J., Weiss, R., Wen, L., Wessel, E. K., Weßels, P., Westphal, T., Wette, K., Whelan, J. T., Whiting, B. F., Whittle, C., Williams, D., Williams, R. D., Williamson, A. R., Willis, J. L., Willke, B., Wimmer, M. H., Winkler, W., Wipf, C. C., Wittel, H., Woan, G., Woehler, J., Wofford, J., Wong, K. W. K., Worden, J., Wright, J. L., Wu, D. S., Wu, G., Yam, W., Yamamoto, H., Yancey, C. C., Yap, M. J., Yu, Hang, Yu, Haocun, Yvert, M., Zadrożny, A., Zanolin, M., Zelenova, T., Zendri, J. -P., Zevin, M., Zhang, L., Zhang, M., Zhang, T., Zhang, Y. -H., Zhao, C., Zhou, M., Zhou, Z., Zhu, S., Zhu, X. J., Zucker, M. E., and Zweizig, J.

Subjects
General Relativity and Quantum Cosmology, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

We report on an all-sky search for periodic gravitational waves in the frequency band 20-475 Hz and with a frequency time derivative in the range of [-1.0, +0.1]e-8 Hz/s. Such a signal could be produced by a nearby spinning and slightly non-axisymmetric isolated neutron star in our galaxy. This search uses the data from Advanced LIGO's first observational run, O1. No periodic gravitational wave signals were observed, and upper limits were placed on their strengths. The lowest upper limits on worst-case (linearly polarized) strain amplitude h0 are 4e-25 near 170 Hz. For a circularly polarized source (most favorable orientation), the smallest upper limits obtained are 1.5e-25. These upper limits refer to all sky locations and the entire range of frequency derivative values. For a population-averaged ensemble of sky locations and stellar orientations, the lowest upper limits obtained for the strain amplitude are 2.5e-25., Comment: Updated reference to just arXiv'ed Einstein@Home paper, fix e-mail in arXiv metadata

Published
2017
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19. Sympathetic structural and electrophysiological remodeling in a rabbit model of reperfused myocardial infarction

Author

Guevara, Amanda, primary, Smith, Charlotte E.R., additional, Wang, Lianguo, additional, Caldwell, Jessica L., additional, Tapa, Srinivas, additional, Stuart, Samantha D. Francis, additional, Ma, Betty W., additional, Ng, G. Andre, additional, Habecker, Beth A., additional, Wang, Zhen, additional, and Ripplinger, Crystal M., additional

Published
2024
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20. 131 Clinical outcomes comparison between radiofrequency ablation vs cryoballoon ablation for paroxysmal atrial fibrillation: an observational cohort study

Author

Antoun, Ibrahim, primary, Kotb, Ahmed, additional, Barker, Joseph, additional, Mavilakandy, Akash, additional, Koev, Ivelin, additional, Vali, Zakariyya, additional, Man, Sharon, additional, Baron, Julia, additional, Taher, AT, additional, Sandilands, Alastair, additional, Somani, Riyaz, additional, and Ng, G Andre, additional

Published
2024
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21. 127 A comparative analysis of conduction system pacing and conventional pacing in patients undergoing atrioventricular node ablation: a systematic review and meta-analysis

Author

Mavilakandy, Akash, primary, Abdelrazik, Ahmed, additional, Abouelmagd, Khaled, additional, Koev, Ivelin, additional, Chotalia, Ravi, additional, Koya, Abdulmalik, additional, Eldeeb, Hany, additional, Ahamed, Hisham, additional, Dhutia, Harshil, additional, Somani, Riyaz, additional, Ng, G. Andre, additional, and Ibrahim, Mokhtar, additional

Published
2024
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23. 124 A comparative analysis of procedural outcomes between pulsed field ablation and very high-powered short duration radiofrequency ablation

Author

Abdelrazik, Ahmed, primary, Mavilakandy, Akash, additional, Koya, Abdulmalik, additional, Koev, Ivelin, additional, Ibrahim, Mokhtar, additional, Chin, Shui Hao, additional, Vali, Zakariyya, additional, Somani, Riyaz, additional, Sandilands, Alastair, additional, Lazdam, Merzaka, additional, and Ng, G. Andre, additional

Published
2024
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24. 117 Real world observational study of pulsed-field ablation for pulmonary vein isolation in a tertiary center in the United Kingdom

Author

Koev, Ivelin, primary, Mavilakandy, Akash, additional, Abdelrazik, Ahmed, additional, Antoun, Ibrahim, additional, Barker, Joseph, additional, Kotb, Ahmed, additional, Man, Sharon, additional, Sandilands, Alastair, additional, Vali, Zakariyya, additional, Ibrahim, Mokhtar, additional, Lazdam, Merzaka, additional, Chin, Shui Hao, additional, Ng, G. Andre, additional, and Somani, Riyaz, additional

Published
2024
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26. Transforming research and relationships through collaborative tribal-university partnerships on Manoomin (wild rice)

Author

Matson, Laura, Ng, G.-H. Crystal, Dockry, Michael, Nyblade, Madeline, King, Hannah Jo, Bellcourt, Mark, Bloomquist, Jeremy, Bunting, Perry, Chapman, Eric, Dalbotten, Diana, Davenport, Mae A., Diver, Karen, Duquain, McKaylee, Graveen, William (Joe), Hagsten, Katherine, Hedin, Kari, Howard, Susannah, Howes, Thomas, Johnson, John, Sr., Kesner, Shannon, Kojola, Erik, LaBine, Roger, Larkin, Daniel J., Montano, Melonee, Moore, Seth, Myrbo, Amy, Northbird, Michael, Porter, Meghan, Robinson, Rich, Santelli, Cara M., Schmitter, Riley, Shimek, Robert, Schuldt, Nancy, Smart, Allison, Strong, Donovan, Torgeson, Joshua, Vogt, Darren, and Waheed, Alexander

Published
2021
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27. Sympathetic structural and electrophysiological remodeling in a rabbit model of reperfused myocardial infarction.

Author

Guevara, Amanda, Smith, Charlotte E. R., Wang, Lianguo, Caldwell, Jessica L., Tapa, Srinivas, Stuart, Samantha D. Francis, Ma, Betty W., Ng, G. Andre, Habecker, Beth A., Wang, Zhen, and Ripplinger, Crystal M.

Subjects
MYOCARDIAL infarction, ACTION potentials, CHONDROITIN sulfates, NEURAL stimulation, ELECTROPHYSIOLOGY
Abstract

Chondroitin sulfate proteoglycans (CSPGs) inhibit sympathetic reinnervation in rodent hearts post-myocardial infarction (MI), causing regional hypoinnervation that is associated with supersensitivity of β-adrenergic receptors and increased arrhythmia susceptibility. To investigate the role of CSPGs and hypoinnervation in the heart of larger mammals, we used a rabbit model of reperfused MI and tested electrophysiological responses to sympathetic nerve stimulation (SNS). Innervated hearts from MI and sham rabbits were optically mapped using voltage and Ca2+-sensitive dyes. SNS was performed with electrical stimulation of the spinal cord, and β-adrenergic responsiveness was tested using isoproterenol. Sympathetic nerve density and CSPG expression were evaluated using immunohistochemistry. CSPGs were robustly expressed in the infarct region of all MI hearts, and the presence of CSPGs was associated with reduced sympathetic nerve density in the infarct versus remote region. Action potential duration (APD) dispersion and tendency for induction of ventricular tachycardia/fibrillation (VT/VF) were increased with SNS in MI but not sham hearts. SNS decreased APD at 80% repolarization (APD80) in MI but not sham hearts, whereas isoproterenol decreased APD80 in both groups. Isoproterenol also shortened Ca2+ transient duration at 80% repolarization in both groups but to a greater extent in MI hearts. Our data suggest that sympathetic remodeling post-MI is similar between rodents and rabbits, with CSPGs associated with sympathetic hypoinnervation. Despite a reduction in sympathetic nerve density, the infarct region of MI hearts remained responsive to both physiological SNS and isoproterenol, potentially through preserved or elevated β-adrenergic responsiveness, which may underlie increased APD dispersion and tendency for VT/VF. NEW & NOTEWORTHY: Here, we show that CSPGs are present in the infarcts of rabbit hearts with reperfused MI, where they are associated with reduced sympathetic nerve density. Despite hypoinnervation, sympathetic responsiveness is maintained or enhanced in MI rabbit hearts, which also demonstrate increased APD dispersion and tendency for arrhythmias following sympathetic modulation. Together, this study indicates that the mechanisms of sympathetic remodeling post-MI are similar between rodents and rabbits, with hypoinnervation likely associated with enhanced β-adrenergic sensitivity. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Compressed Deep Learning Models for Wearable Atrial Fibrillation Detection through Attention.

Author

Mäkynen, Marko, Ng, G. Andre, Li, Xin, Schlindwein, Fernando S., and Pearce, Timothy C.

Subjects
*ATRIAL fibrillation, *ARTIFICIAL intelligence, *WEARABLE technology, *MARKETING channels, *PHOTOPLETHYSMOGRAPHY, *MEDICAL personnel
Abstract

Deep learning (DL) models have shown promise for the accurate detection of atrial fibrillation (AF) from electrocardiogram/photoplethysmography (ECG/PPG) data, yet deploying these on resource-constrained wearable devices remains challenging. This study proposes integrating a customized channel attention mechanism to compress DL neural networks for AF detection, allowing the model to focus only on the most salient time-series features. The results demonstrate that applying compression through channel attention significantly reduces the total number of model parameters and file size while minimizing loss in detection accuracy. Notably, after compression, performance increases for certain model variants in key AF databases (ADB and C2017DB). Moreover, analyzing the learned channel attention distributions after training enhances the explainability of the AF detection models by highlighting the salient temporal ECG/PPG features most important for its diagnosis. Overall, this research establishes that integrating attention mechanisms is an effective strategy for compressing large DL models, making them deployable on low-power wearable devices. We show that this approach yields compressed, accurate, and explainable AF detectors ideal for wearables. Incorporating channel attention enables simpler yet more accurate algorithms that have the potential to provide clinicians with valuable insights into the salient temporal biomarkers of AF. Our findings highlight that the use of attention is an important direction for the future development of efficient, high-performing, and interpretable AF screening tools for wearable technology. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart

Author

Guevara, Amanda, primary, Smith, Charlotte E. R., additional, Caldwell, Jessica L., additional, Ngo, Lena, additional, Mott, Lilian R., additional, Lee, I-Ju, additional, Tapa, Srinivas, additional, Wang, Zhen, additional, Wang, Lianguo, additional, Woodward, William R., additional, Ng, G. Andre, additional, Habecker, Beth A., additional, and Ripplinger, Crystal M., additional

Published
2024
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35. Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

Author

Anderson, Craig S., Huang, Yining, Lindley, Richard I., Chen, Xiaoying, Arima, Hisatomi, Chen, Guofang, Li, Qiang, Billot, Laurent, Delcourt, Candice, Bath, Philip M., Broderick, Joseph P., Demchuk, Andrew M., Donnan, Geoffrey A., Durham, Alice C., Lavados, Pablo M., Lee, Tsong-Hai, Levi, Christopher, Martins, Sheila O., Olavarria, Veronica V., Pandian, Jeyaraj D., Parsons, Mark W., Pontes-Neto, Octavio M., Ricci, Stefano, Sato, Shoichiro, Sharma, Vijay K., Silva, Federico, Song, Lili, Thang, Nguyen H., Wardlaw, Joanna M., Wang, Ji-Guang, Wang, Xia, Woodward, Mark, Chalmers, John, Robinson, Thompson G., Kim, Jong S., Stapf, Christian, Simes, R. John, Hankey, Graeme J., Sandercock, Peter, Bousser, Marie-Germaine, Wong, K.S. Lawrence, Scaria, Anish, Hirakawa, Yoichiro, Moullaali, Tom J., Carcel, Cheryl, Gordon, Penny, Fuentes-Patarroyo, Sully X., Benito, Dino, Chen, Ruiqi, Cao, Yongjun, Kunchok, Amy, Winters, Stephen, Coutts, Shelagh, Yoshimura, Sohei, You, Shoujiang, Yang, Jie, Wu, Guojun, Zhang, Shihong, Manning, Lisa, Mistri, Amit, Haunton, Victoria, Minhas, Jatinder, Malavera, Alejandra, Lim, Joyce, Liu, Leibo, Kumar, Namrata N., Tay, Nicole, Jenson, Kerry, Richtering, Sarah, Tucker, Sharon, Knight, Elizabeth, Ivanova, Elizaveta, Thembani, Emma, Odgers, Elizabeth, Sanders, Elizabeth, Small, Sabrina, Vaghasiya, Ruchita, Armenis, Manuela, Donnelly, Paul, Baig, Merza A., Blacklock, Nick, Naidu, Bala, Monaghan, Helen, Smith, Phillipa, Glass, Parisa, Bai, Xuejie, Li, Qiancheng, Zhu, Pingping, Kong, Liang, He, Ruihong, Zhao, He, Lv, Jiajie, Jia, Haijing, Xi, Zhen, Cong, Yuhan, Cui, Buliang, Deng, Hua, Guo, Ying, He, Lingyu, Jia, Ruolan, Li, Nan, Li, Wei, Liu, Mengxiao, Zhang, Meng, Xu, Ziwei, Zhang, Ting, Zhao, Yan, Gregory, Philip, In, Yunjeong, Kim, Su J., Ahn, Jung E., Kim, Sul H., Hong, Young L., González-McCawley, Francisca, Martins, Magda C.O., Portales, Bernardita, Wang, Ching-Yi, Ryu, Shan-Jen, Aujla, Hardeep, Lewin, Sue, Kumar, Tracy, Barrows, Sara, Ebraimo, Ahtasam, Uyen, Hong H., Giang, Nguyen A., Linh, Le T.M., An, Le T.T., Phuong, Do M., Ngoc, Pham V.B., Hang, Nguyen M., Tran, Nguyen T.B., Hien, Ha T.T., Yen, Mai B., Tram, Ngo T.B., Truc, Tran T.T., Hoa, Nguyen A., Thuan, Nguyen T.B., Oanh, Ha T.K., Arora, Deepti, Verma, Shweta J., Krause, M., Priglinger, M., Day, S., Jala, S., Davies, L., Ray, E., Celestino, S., Law, L.Y., Wijeratne, T., Ng, G., Nagao, K., Weiss, G., Titton, N., Batista, C., Zãn, D., Carbonera, L., Ferreira, K., Castro, R., Martins Filho, R.K., Carvalho, M., Libardi, M., Martins, G., Fagundes, D., Baron, G., Boehringer, A., Barbosa, J., Bazan, R., Braga, G., Luvizutto, G., Ribeiro, P., Winckler, F., Moro, C., Longo, A., Liberato, R., Barbosa, R., Magalhães, P., Portal, M., Martin, K., Souza, A., Cuervo, D., Perin, D., Marques, L., Oliveira, F., Battaglini, M., Lourenço, F., Silva, G., Duarte, L., Alves, M., Sousa, J., Uhehara, M., Brunser, A., Mazzón, E., Spencer, M., Acosta, I., Rojo, A., Rivas, R., Klapp, C., Carvallo, L., Carvallo, P., Mansilla, E., Flores, J., Alvarado, M., Herrera, A., Reyes, C., Jurado, F., Bustamante, G., Bravo, L., Matamala, J.M., Guerrero, R., Zhou, S., Ping, L., Liu, W., Liu, L., Tian, Y., Xu, H., Wang, J., Wang, L., Zhen, Z., Zhang, J., Yan, M., Zhang, Q., Tao, X., Liu, C., Shi, J., Zhang, X., Tai, L., Xu, L., Lu, H., Nie, H., Li, X., Zhou, J., Liu, Y., Gong, P., Zhao, H., Li, R., Wang, X., Chen, Q., Li, Y., Wu, L., Jia, L., Guo, X., Chen, G., Lin, B., Zhu, W., Yang, K., Zhang, Z., Xie, C., Wu, D., Wang, Y., Liu, D., Liu, Z., Liang, L., Cao, Q., Xia, J., Weng, Y., Li, J., Xu, T., Geng, D., Yan, X., Wang, D., Zhao, N., Tang, Z., Yin, W., Wang, S., Huang, W., Yang, Y., Song, A., Hao, Y., Zhang, A., 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2019
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36. Correction: Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies (Critical Care, (2023), 27, 1, (3), 10.1186/s13054-022-04294-5)

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McNicholas B. A., Mcnicholas, B, Rezoagli, E, Simpkin, A, Khanna, S, Suen, J, Yeung, P, Brodie, D, Bassi, G, Pham, T, Bellani, G, Fraser, J, Laffey, J, Al-Dabbous, T, Alfoudri, H, Shamsah, M, Alhadad, Q, Hanan, M, Elapavaluru, S, Berg, A, Horn, C, Abdelhalim, A, Amer, A, Elnaggar, C, Hassan, A, Abdelaziz, A, Abdelhalim, M, Orabi, Y, Alaraji, Z, Muhaisen, M, Almasri, L, Mustafa, D, Hamdan, S, Al-Saba'a, Y, Dalloul, Z, Alkahlout, M, Jaber, H, Aldabbourosama, O, Hussein, A, Emad, Z, Khaled, S, Mohamed, N, Hassanin, E, Hamdi, A, Ragab, A, Azizeldin, M, Mayasi, Y, Schroll, S, Meyer, D, Velazco, J, Ploskanych, L, Fikes, W, Bagewadi, R, Dao, M, White, H, Laviena, A, Ehlers, A, Shalabi-McGuire, M, Witt, T, Grazioli, L, Lorini, L, Grandin, E, Nunez, J, Reyes, T, O'Briain, D, Hunter, S, Ramanan, M, Affleck, J, Veerendra, H, Rai, S, Russell-Brown, J, Nourse, M, Joseph, M, Mitchell, B, Tenzer, M, Abe, R, Cho, H, Jeong, I, Rahman, N, Kakar, V, Sun, H, Hanley, A, Brozzi, N, Mehkri, O, Krishnan, S, Duggal, A, Houltham, S, Graf, J, Diaz, R, Orrego, R, Delgado, C, Gonzalez, J, Sanchez, M, Piagnerelli, M, Sarrazin, J, Zabert, G, Espinosa, L, Delgado, P, Delgado, V, Rincon, D, Yanten, A, Duque, M, Abouelmagd, K, Elhazmi, A, Al-Hudaib, A, Javidfar, J, Callahan, M, Dong, A, D'Orleans, C, Taufik, M, Wardoyo, E, Gunawan, M, Trisnaningrum, N, Irawany, V, Rayhan, M, Panigada, M, Pesenti, A, Zanella, A, Grasselli, G, Colombo, S, Martinet, C, Florio, G, Antonelli, M, Carelli, S, Grieco, D, Asaki, M, Hoshino, K, Salazar, L, Monsalve, M, Cosgrave, D, Atif, M, Qutishat, F, Laffey, C, Van Der Walt, M, Mccaffrey, J, Bone, A, Hakeem, Y, Winearls, J, Tallott, M, Thomson, D, Joubert, I, Arnold-Day, C, Piercy, J, van Zyl Smit, R, Miller, M, Seymour, L, van Heyningen, F, Teyangesikayi, G, Fredericks, D, Hssain, A, Aliudin, J, Alqahtani, A, Mohamed, K, Mohamed, A, Tan, D, Villanueva, J, Zaqout, A, Kurtzman, E, Ademi, A, Dobrita, A, El Aoudi, K, Segura, J, Giwangkancana, G, Ohshimo, S, Osatnik, J, Joosten, A, Torres, A, Yang, M, Motos, A, Luna, C, Arancibia, F, Williams, V, Noel, A, Luque, N, Fantini, M, Garcia, R, Alvarez, E, Greti, A, Ceccato, A, Sanchez, A, Vazquez, A, Roche-Campo, F, Franch-Llasat, D, Tuazon, D, Amato, M, Cassimiro, L, Pola, F, Ribeiro, F, Fonseca, G, Dalton, H, Desai, M, Osborn, E, Deeb, H, Arcadipane, A, Martucci, G, Panarello, G, Vitiello, S, Bianco, C, Occhipinti, G, Rossetti, M, Cuffaro, R, Cho, S, Whitman, G, El Sayed, M, Mokhtar, W, El-Shenawy, E, Shimizu, H, Moriyama, N, Kim, J, Kitamura, N, Gebauer, J, Yokoyama, T, Al-Fares, A, Buabbas, S, Alamad, E, Alawadhi, F, Alawadi, K, Khalefa, M, Al Ajeel, N, Aly, M, Al-Saleh, A, Naanouh, A, Elshourbgy, A, Gad, M, Elrazaz, R, Khadadah, I, Almumin, A, Altarakma, H, Albannay, H, Alsaleh, M, Radwan, M, Saadallah, I, Tanaka, H, Hashimoto, S, Yamazaki, M, Oh, T, Epler, M, Forney, C, Kruse, L, Feister, J, Williamson, J, Grobengieser, K, Gnall, E, Golden, S, Caroline, M, Shapiro, T, Karaj, C, Thome, L, Sher, L, Vanderland, M, Welch, M, Mcdermott, S, Brain, M, Mineall, S, Unwin, M, Chen, L, Trezise, T, Mckeon, L, Kimura, D, Brazzi, L, Sales, G, Montrucchio, G, Ogston, T, Nagpal, D, Fischer, K, Lorusso, R, van Bussell, B, De Piero, M, Mariani, S, Rangappa, R, Shetty, R, Rai, P, Ganesan, A, Esperatti, M, Fuentes, N, Gonzalez, M, Carton, E, Sen, A, Palacios, A, Rainey, D, Samoukoviv, G, Campisi, J, Durham, L, Neumann, E, Seefeldt, C, Falcucci, O, Emmrich, A, Guy, J, Johns, C, Potzner, K, Zimmermann, C, Espinal, A, Buchtele, N, Schwameis, M, Korhnfehl, A, Brock, R, Staudinger, T, Stecher, S, Barnikel, M, Anton, S, Pawlikowski, A, Zaaqoq, A, Galloway, L, Merley, C, Nichol, A, Csete, M, Quesada, L, Saba, I, Kasugai, D, Hiraiwa, H, Tanaka, T, Marwali, E, Purnama, Y, Dewayanti, S, Ardiyan, Juzar, D, Siagian, D, Chen, Y, Ogino, M, Nasa, P, Matthew, C, Majeed, N, Ratsep, I, Post, A, Sillaots, P, Krund, A, Lehiste, M, Lepik, T, Manetta, F, Mihelis, E, Sarmiento, I, Narasimhan, M, Varrone, M, Komats, M, Garcia-Diaz, J, 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Fukuda, M, Liu, K, Pelosi, P, Battaglini, D, Jimenez, J, Bastos, D, Gaiao, S, Rusmawatiningtyas, D, Cho, Y, Lee, S, Kawasaki, T, Munshi, L, Sakiyalak, P, Nitayavardhana, P, Elagili, M, Salem, T, Seitz, T, Arora, R, Kent, D, Marino, D, Parwar, S, Cheng, A, Miller, J, Fujitani, S, Shimizu, N, Madhok, J, Owyang, C, Buscher, H, Reynolds, C, Maasikas, O, Aleksanbeljantsev, Mihnovits, V, Akimoto, T, Aizawa, M, Horibe, K, Onodera, R, Hodgson, C, Burrell, A, Young, M, George, T, Shekar, K, Mcguinness, N, Irvine, L, Flynn, B, Endo, T, Sugiyama, K, Shimizu, K, Fan, E, Exconde, K, Ichiba, S, Binnawara, M, Lussier, L, Lotz, G, Malfertheiner, M, Maier, L, Dreier, E, Kusumastuti, N, Mccloskey, C, Dabaliz, A, Elshazly, T, Smith, J, Szuldrzynski, K, Bielanski, P, Wille, K, Murthy, S, Parhar, K, Fiest, K, Codan, C, Shahid, A, Fayed, M, Evans, T, Gutierrez, A, Song, T, Rose, R, Bennett, S, Richardson, D, Peek, G, Arora, L, Rappapport, K, Rudolph, K, Sibenaller, Z, Stout, L, Walter, A, Herr, D, Vedadi, N, Bartlett, R, Thompson, S, Hoffman, J, Ying, X, Williams, B, Sanchez, E, Akwani, C, Kennedy, R, Elhadi, M, Griffee, M, Mone, M, Ciullo, A, Kida, Y, Roca, R, Riera, J, Contreras, S, Alegre, C, Kay, C, Fischer, I, Renner, E, Taniguci, H, Lee, J, Plotkin, D, Citarella, B, Merson, L, Hartley, E, Lubis, B, Ikeyama, T, Alhamad, A, Fathi, M, Hadhoud, M, Alhouri, H, Mechi, A, Alyasiri, M, Elsaid, M, Shahla, H, Bhaskar, B, Jung, J, Mcguinness, S, Eastwood, G, Marta, S, Guarracino, F, Gerle, S, Coxon, E, Claro, B, Eleisawy, M, Osama, H, Loverde, D, Patil, N, Parrini, V, Mcbride, A, Negaard, K, Ratsch, A, Uribe, J, Peris, A, Sanders, M, Emerson, D, Kamal, M, Faida, H, Povoa, P, Francis, R, Cherif, A, Joseph, S, Di Nardo, M, Heard, M, Kyle, K, Blackwell, R, Ouyahia, A, Biston, P, Jeong, H, Smith, R, Prawira, Y, Garcia, A, Salterain, N, Meyns, B, Elnasser, M, Moreno, M, Walia, R, Mehta, A, Schweda, A, Williams, M, Emadamkhatirah, Kim, K, Assad, A, Giraldo, E, Karolak, W, Balik, M, Pocock, E, Gajkowski, E, Masafumi, K, Barrett, N, Takeyama, Y, Park, S, Amin, F, Andriyani, F, Sudakevych, S, Schnur, J, Vera, M, Cornejo, R, Schwarz, P, Mardini, A, de Paula, T, Neto, A, Villoldo, A, Colafranceschi, A, Iglesias, A, Granjean, J, Melro, L, Romualdo, G, Gaia, D, Souza, H, Galas, F, Mendiluce, R, Sosa, A, Martinez, I, Kurosawa, H, Almoshantaf, M, Salgado, J, Hugi-Mayr, B, Charbonneau, E, Barzilai, V, Monteiro, V, de Souza, R, Harper, M, Siddig, N, Suzuki, H, Adams, C, Brieva, J, Khamees, A, Graige, F, Supriatna, M, Nyale, G, Eltatar, F, Fatani, J, Baeissa, H, Masri, A, Rabie, A, Hui, M, Yamane, M, Jung, H, Margaret, A, Nacpil, N, Ruck, K, Bakken, R, Jara, C, Felton, T, Tharwat, S, Berra, L, Shah, B, Chakraborty, A, Cardona, M, Capatos, G, Akkanti, B, Orija, A, Jain, H, Ito, A, Muftah, M, Housni, B, Aldhalia, A, Low, S, Iihara, K, Chavez, J, Ramanathan, K, Naidoo, K, Seppelt, I, Vandyk, M, Macdonald, S, Hafez, W, Mcgregor, R, Siebenaler, T, Flynn, H, Lofton, K, Aokage, T, Kvirkvelia, B, Shigemitsu, K, Moscatelli, A, Fiorentino, G, Baumgaertel, M, Mba, S, Assy, J, Hutahaean, A, Roush, H, Sichting, K, Alessandri, F, Burns, D, Alkhubouli, T, Nasrallah, A, Salt, G, Garabedian, C, Millar, J, Sim, M, Mattke, A, Mcauley, D, Tadili, J, Frenzel, T, Bar-Lavie, Y, Ortiz, A, Stone, J, Attokaran, A, Farquharson, M, Patel, B, Gunning, D, Baillie, K, Adem, S, Watson, P, Tamai, K, Sajinadiyasa, G, Kanyawati, D, Salgado, M, Sassine, A, Yudo, B, Mccaul, S, Lee, B, Afek, A, Iwashita, Y, Fadlalmola, H, Semedi, B, Mansour, N, Metiva, J, Van Belle, N, Martin-Loeches, I, Al-Sadawi, M, Kirakli, C, Shimaa, A, Abdurraouf, A, Ivatt, L, Moharam, S, Woon, C, Kang, H, Smith, T, James, E, Al-Rawas, N, Almjersah, A, Iwasaki, Y, Ashour, H, Embarek, H, King-Chung, K, Gudzenko, V, Taccone, F, Perdhana, F, Lamarche, Y, Ribeiro, J, Bradic, N, Van den Bossche, K, Lansink, O, Singh, G, Debeuckelaere, G, Stelfox, H, Yi, C, Elia, J, Tribble, T, Shankar, S, Padmanabhan, R, Hallinan, B, Paoletti, L, Leyva, Y, Fykuda, T, Badulak, J, Koch, J, Janowaik, L, Hackman, A, Hernandez, D, Osofsky, J, Donadello, K, Lawang, A, Fine, J, Davidson, B, Abdehaleem, I, McNicholas B. A., Rezoagli E., Simpkin A. J., Khanna S., Suen J. Y., Yeung P., Brodie D., Bassi G. L., Pham T., Bellani G., Fraser J. F., Laffey J., Al-Dabbous T., Alfoudri H., Shamsah M., Alhadad Q., Hanan M., Elapavaluru S., Berg A., Horn C., Abdelhalim A. R. M. E., Amer A. E., Elnaggar C. O. R., Hassan A. A., Abdelaziz A., Abdelhalim M., Orabi Y. S. S. A., Alaraji Z. A., Muhaisen M. R., Almasri L., Mustafa D., Hamdan S., Al-Saba'a Y., Dalloul Z., Alkahlout M., Jaber H., Aldabbourosama O., Hussein A. A. R. M., Emad Z. K., Khaled S., Mohamed N., Hassanin E., Hamdi A., Ragab A., Azizeldin M. G., Mayasi Y., Schroll S., Meyer D., Velazco J., Ploskanych L., Fikes W., Bagewadi R., Dao M., White H., Laviena A. B., Ehlers A., Shalabi-McGuire M., Witt T., Grazioli L., Lorini L., Grandin E. W., Nunez J., Reyes T., O'Briain D., Hunter S., Ramanan M., Affleck J., Veerendra H. H., Rai S., Russell-Brown J., Nourse M., Joseph M., Mitchell B., Tenzer M., Abe R., Cho H. J., Jeong I. S., Rahman N., Kakar V., Sun H., Hanley A., Brozzi N., Mehkri O., Krishnan S., Duggal A., Houltham S., Graf J., Diaz R., Orrego R., Delgado C., Gonzalez J., Sanchez M. S., Piagnerelli M., Sarrazin J. V., Zabert G., Espinosa L., Delgado P., Delgado V., Rincon D. F. B., Yanten A. M. M., Duque M. B., Abouelmagd K., Elhazmi A., Al-Hudaib A., Javidfar J., Callahan M., Dong A., D'Orleans C. C., Taufik M. A., Wardoyo E. Y., Gunawan M., Trisnaningrum N. S., Irawany V., Rayhan M., Panigada M., Pesenti A., Zanella A., Grasselli G., Colombo S., Martinet C., Florio G., Antonelli M., Carelli S., Grieco D. L., Asaki M., Hoshino K., Salazar L., Monsalve M. A. M., McNicholas B., Cosgrave D., Atif M., Qutishat F., Laffey C., Van Der Walt M., McCaffrey J., Bone A., Hakeem Y., Winearls J., Tallott M., Thomson D., Joubert I., Arnold-Day C., Piercy J., van Zyl Smit R., Miller M., Seymour L., van Heyningen F., Teyangesikayi G., Fredericks D., Hssain A. 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M., Altarakma H., Albannay H., Alsaleh M. K., Radwan M. S. A., Saadallah I. A., Tanaka H., Hashimoto S., Yamazaki M., Oh T. -H., Epler M., Forney C., Kruse L., Feister J., Williamson J., Grobengieser K., Gnall E., Golden S., Caroline M., Shapiro T., Karaj C., Thome L., Sher L., Vanderland M., Welch M., McDermott S., Brain M., Mineall S., Unwin M., Chen L., Trezise T., McKeon L., Kimura D., Brazzi L., Sales G., Montrucchio G., Ogston T., Nagpal D., Fischer K., Lorusso R., van Bussell B., De Piero M. E., Mariani S., Rangappa R., Shetty R. M., Rai P. S., Ganesan A., Esperatti M., Fuentes N. A., Gonzalez M. E., Carton E. G., Sen A., Palacios A., Rainey D., Samoukoviv G., Campisi J., Durham L., Neumann E., Seefeldt C., Falcucci O., Emmrich A., Guy J., Johns C., Potzner K., Zimmermann C., Espinal A., Buchtele N., Schwameis M., Korhnfehl A., Brock R., Staudinger T., Stecher S. -S., Barnikel M., Anton S., Pawlikowski A., Zaaqoq A., Galloway L. A., Merley C., Nichol A., Csete M., Quesada L., Saba I., Kasugai D., Hiraiwa H., Tanaka T., Marwali E., Purnama Y., Dewayanti S. R., Juzar D. A., Siagian D., Chen Y. -S., Ogino M., Nasa P., Matthew C., Majeed N. A., Ratsep I., Post A. -M., Sillaots P., Krund A., Lehiste M. -H., Lepik T., Manetta F., Mihelis E., Sarmiento I. C., Narasimhan M., Varrone M., Komats M., Garcia-Diaz J., Harmon C., Satyapriya S. V., Bhatt A., Mokadam N. A., Uribe A., Gonzalez A., Shi H., McKeown J., Pasek J., Fiorda J., Echeverria M., Moreno R., Zakhary B., Cavana M., Cucino A., Foti G., Giani M., Fumagalli B., Chiumello D., Castagna V., Dell'Amore A., Navalesi P., Shum H. -P., Vuysteke A., Usman A., Acker A., Smood B., Mergler B., Sertic F., Subramanian M., Sperry A., Rizer N., Burhan E., Rasmin M., Akmal E., Sitompul F., Lolong N., Naivedh B., Erickson S., Barrett P., Dean D., Daugherty J., Loforte A., Khan I., Quraishi M. A., DeSantis O., So D., Kandamby D., Mandei J. 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A., Seitz T., Arora R., Kent D., Marino D., Parwar S., Cheng A., Miller J., Fujitani S., Shimizu N., Madhok J., Owyang C., Buscher H., Reynolds C., Maasikas O., AleksanBeljantsev, Mihnovits V., Akimoto T., Aizawa M., Horibe K., Onodera R., Hodgson C., Burrell A., Young M., George T., Shekar K., McGuinness N., Irvine L., Flynn B., Endo T., Sugiyama K., Shimizu K., Fan E., Exconde K., Ichiba S., Binnawara M., Lussier L., Lotz G., Malfertheiner M., Maier L., Dreier E., Kusumastuti N. P., McCloskey C., Dabaliz A. -A., Elshazly T. B., Smith J., Szuldrzynski K. S., Bielanski P., Wille K., Murthy S., Parhar K. K. S., Fiest K. M., Codan C., Shahid A., Fayed M., Evans T., Garcia R., Gutierrez A., Song T., Rose R., Bennett S., Richardson D., Peek G., Arora L., Rappapport K., Rudolph K., Sibenaller Z., Stout L., Walter A., Herr D., Vedadi N., Bartlett R., Thompson S., Hoffman J., Ying X., Williams B., Sanchez E., Akwani C., Kennedy R., Elhadi M., Griffee M., Mone M., Ciullo A., Kida Y., Roca R. F., Riera J. I., Contreras S., Alegre C., Kay C., Fischer I., Renner E., Taniguci H., Lee J., Plotkin D., Citarella B. W., Merson L., Hartley E., Lubis B., Ikeyama T., Alhamad A., Fathi M., Hadhoud M. M., Alhouri H., Mechi A., Alyasiri M. S., Elsaid M. Z. A., Shahla H., Bhaskar B., Jung J. -S., McGuinness S., Eastwood G., Marta S. R., Guarracino F., Gerle S., Coxon E., Claro B., Eleisawy M., Osama H., Loverde D., Patil N., Parrini V., McBride A., Negaard K., Ratsch A., Uribe J. D., Peris A., Sanders M., Emerson D., Kamal M., Faida H., Povoa P., Francis R., Cherif A., Joseph S., Di Nardo M., Heard M., Kyle K., Blackwell R. A., Ouyahia A., Biston P., Jeong H. W., Smith R., Prawira Y., Garcia A. H., Salterain N., Meyns B., Elnasser M., Moreno M., Walia R., Mehta A., Schweda A., Williams M., EmadAmkhatirah, Kim K. H., Assad A., Giraldo E., Karolak W., Balik M., Pocock E., Gajkowski E., Masafumi K., Barrett N., Takeyama Y., Park S., Amin F., Andriyani F. M., Sudakevych S., Schnur J., Vera M., Cornejo R., Schwarz P., Mardini A. C., de Paula T., Neto A. S., Villoldo A., Colafranceschi A. S., Iglesias A. U., Granjean J., Melro L. M. G., Romualdo G. F., Gaia D., Souza H., Galas F., Mendiluce R. M., Sosa A., Martinez I., Kurosawa H., Almoshantaf M. B., Salgado J., Hugi-Mayr B., Charbonneau E., Barzilai V. S., Monteiro V., de Souza R. R., Harper M., Siddig N., Suzuki H., Adams C., Brieva J., Khamees A., Graige F., Supriatna M., Nyale G., Eltatar F. S., Fatani J., Baeissa H., Masri A. A. L., Rabie A., Hui M. Y., Yamane M., Jung H., Margaret A. M., Nacpil N., Ruck K., Bakken R., Jara C., Felton T., Tharwat S., Berra L., Shah B., Chakraborty A., Cardona M., Capatos G., Akkanti B., Orija A., Jain H., Ito A., Muftah M., Housni B., Aldhalia A., Low S., Iihara K., Chavez J., Ramanathan K., Naidoo K., Seppelt I., VanDyk M., MacDonald S., Hafez W., McGregor R., Siebenaler T., Flynn H., Lofton K., Aokage T., Kvirkvelia B., Shigemitsu K., Moscatelli A., Fiorentino G., Baumgaertel M., Mba S. E., Assy J., Hutahaean A., Roush H., Sichting K. A., Alessandri F., Burns D., Alkhubouli T. H., Nasrallah A., Salt G., Garabedian C. P., Millar J., Sim M., Mattke A., McAuley D., Tadili J., Frenzel T., Bar-Lavie Y., Ortiz A. B., Stone J., Attokaran A., Farquharson M., Patel B., Gunning D., Baillie K., Adem S., Watson P., Tamai K., Sajinadiyasa G. K., Kanyawati D., Salgado M., Sassine A., Yudo B., McCaul S., Lee B., Lee S. M., Afek A., Iwashita Y., Fadlalmola H., Semedi B. P., Mansour N. 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A., Seitz T., Arora R., Kent D., Marino D., Parwar S., Cheng A., Miller J., Fujitani S., Shimizu N., Madhok J., Owyang C., Buscher H., Reynolds C., Maasikas O., AleksanBeljantsev, Mihnovits V., Akimoto T., Aizawa M., Horibe K., Onodera R., Hodgson C., Burrell A., Young M., George T., Shekar K., McGuinness N., Irvine L., Flynn B., Endo T., Sugiyama K., Shimizu K., Fan E., Exconde K., Ichiba S., Binnawara M., Lussier L., Lotz G., Malfertheiner M., Maier L., Dreier E., Kusumastuti N. P., McCloskey C., Dabaliz A. -A., Elshazly T. B., Smith J., Szuldrzynski K. S., Bielanski P., Wille K., Murthy S., Parhar K. K. S., Fiest K. M., Codan C., Shahid A., Fayed M., Evans T., Garcia R., Gutierrez A., Song T., Rose R., Bennett S., Richardson D., Peek G., Arora L., Rappapport K., Rudolph K., Sibenaller Z., Stout L., Walter A., Herr D., Vedadi N., Bartlett R., Thompson S., Hoffman J., Ying X., Williams B., Sanchez E., Akwani C., Kennedy R., Elhadi M., Griffee M., Mone M., Ciullo A., Kida Y., Roca R. F., Riera J. I., Contreras S., Alegre C., Kay C., Fischer I., Renner E., Taniguci H., Lee J., Plotkin D., Citarella B. W., Merson L., Hartley E., Lubis B., Ikeyama T., Alhamad A., Fathi M., Hadhoud M. M., Alhouri H., Mechi A., Alyasiri M. S., Elsaid M. Z. A., Shahla H., Bhaskar B., Jung J. -S., McGuinness S., Eastwood G., Marta S. R., Guarracino F., Gerle S., Coxon E., Claro B., Eleisawy M., Osama H., Loverde D., Patil N., Parrini V., McBride A., Negaard K., Ratsch A., Uribe J. D., Peris A., Sanders M., Emerson D., Kamal M., Faida H., Povoa P., Francis R., Cherif A., Joseph S., Di Nardo M., Heard M., Kyle K., Blackwell R. A., Ouyahia A., Biston P., Jeong H. W., Smith R., Prawira Y., Garcia A. H., Salterain N., Meyns B., Elnasser M., Moreno M., Walia R., Mehta A., Schweda A., Williams M., EmadAmkhatirah, Kim K. H., Assad A., Giraldo E., Karolak W., Balik M., Pocock E., Gajkowski E., Masafumi K., Barrett N., Takeyama Y., Park S., Amin F., Andriyani F. 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M., Nacpil N., Ruck K., Bakken R., Jara C., Felton T., Tharwat S., Berra L., Shah B., Chakraborty A., Cardona M., Capatos G., Akkanti B., Orija A., Jain H., Ito A., Muftah M., Housni B., Aldhalia A., Low S., Iihara K., Chavez J., Ramanathan K., Naidoo K., Seppelt I., VanDyk M., MacDonald S., Hafez W., McGregor R., Siebenaler T., Flynn H., Lofton K., Aokage T., Kvirkvelia B., Shigemitsu K., Moscatelli A., Fiorentino G., Baumgaertel M., Mba S. E., Assy J., Hutahaean A., Roush H., Sichting K. A., Alessandri F., Burns D., Alkhubouli T. H., Nasrallah A., Salt G., Garabedian C. P., Millar J., Sim M., Mattke A., McAuley D., Tadili J., Frenzel T., Bar-Lavie Y., Ortiz A. B., Stone J., Attokaran A., Farquharson M., Patel B., Gunning D., Baillie K., Adem S., Watson P., Tamai K., Sajinadiyasa G. K., Kanyawati D., Salgado M., Sassine A., Yudo B., McCaul S., Lee B., Lee S. M., Afek A., Iwashita Y., Fadlalmola H., Semedi B. P., Mansour N. M., Metiva J., Van Belle N., Martin-Loeches I., Al-Sadawi M., Kirakli C., Shimaa A. -T., Abdurraouf A., Ivatt L., Moharam S., Woon C. Y., Kang H. M., Smith T., James E., Al-Rawas N., Almjersah A., Iwasaki Y., Ashour H., Embarek H., King-Chung K. C., Gudzenko V., Taccone F., Perdhana F., Lamarche Y., Ribeiro J. M., Bradic N., Van den Bossche K., Lansink O., Singh G., Debeuckelaere G., Stelfox H. T., Yi C., Elia J., Tribble T., Shankar S., Padmanabhan R., Hallinan B., Paoletti L., Leyva Y., Fykuda T., Badulak J., Koch J., Janowaik L., Hackman A., Hernandez D., Osofsky J., Donadello K., Lawang A., Fine J., Davidson B., Vazquez A. O. R., and Abdehaleem I.

Abstract

Following publication of the original article [1], the authors identified that the collaborating authors part of the collaborating author group CCCC Consortium was missing. The collaborating author group is available and included as Additional file 1 in this article.

Published
2023

37. Artificial intelligence for ventricular arrhythmia capability using ambulatory electrocardiograms

Author

Barker, Joseph, primary, Li, Xin, additional, Kotb, Ahmed, additional, Mavilakandy, Akash, additional, Antoun, Ibrahim, additional, Thaitirarot, Chokanan, additional, Koev, Ivelin, additional, Man, Sharon, additional, Schlindwein, Fernando S, additional, Dhutia, Harshil, additional, Chin, Shui Hao, additional, Tyukin, Ivan, additional, Nicolson, William B, additional, and Ng, G Andre, additional

Published
2024
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39. The Feasibility, Safety and Outcome of Very High-Power Short Duration Radiofrequency Ablation in Pulmonary Vein Isolation: A Real-World Observation Study.

Author

Mavilakandy, Akash, Koev, Ivelin, Sidhu, Bharat, Kotb, Ahmed, Antoun, Ibrahim, Man, Sharon H., Vali, Zakariyya, Pooranachandran, Vivetha, Barker, Joseph, Panchal, Gaurav, Xin Li, and Ng, G. André

Abstract

Background: Pulmonary vein isolation (PVI) ablation is the established gold standard therapy for patients with symptomatic drug refractory atrial fibrillation (AF). Advancements in radiofrequency (RF) ablation, have led to the development of the novel contact force-sensing temperature-controlled very high-power short-duration (vHPSD) RF ablation. This setting delivers 90 W for up to 4 seconds with a constant irrigation flow rate of 8 mL/min. The aim of this study was to compare procedural outcomes and safety with conventional radiofrequency ablation. Methods: An observational study was conducted with patients who underwent first time PVI ablation between August 2020 and January 2022. The cohort was divided into: (1) vHPSD ablation; (2) High-power short duration (HPSD) ablation; (3) THERMOCOOL SMARTTOUCH™ SF (STSF). The vHPSD ablation group was prospectively recruited while the HPSD and STSF group were retrospectively collected. Primary outcomes were procedural success, PVI duration, ablation duration and incidence of perioperative adverse events. Secondary outcomes were intraprocedural morphine and midazolam requirement. Results: A total of 175 patients were included in the study with 100, 30 and 45 patients in the vHPSD, HPSD and STSF group, respectively. PVI was successfully attained in all vHPSD patients. vHPSD demonstrated significantly reduced time required for PVI and total energy application in comparison to the HPSD and STSF groups (67.7 ± 29.7 vs. 92.9 ± 25.7 vs. 93.6 ± 29.1 min, p < 0.0001; 9.87 ± 4.16 vs. 33.9 ± 7.49 vs. 36.0 ± 10.5 min, p < 0.0001, respectively). Intravenous morphine and midazolam requirement was lower in the vHPSD group compared to the HPSD and STSF groups (10.2 ± 3.43 vs. 16.1 ± 4.58 vs. 15.3 ± 3.94 mg, p < 0.0001; 4.04 ± 3.24 vs. 8.63 ± 5.22 vs. 8.58 ± 4.72 mg, p < 0.0001). One cardiac tamponade was observed in both the vHPSD and HPSD groups while the STSF group exhibited an embolic stoke and two pericardial effusions that did not require drainage. Conclusions: In this study, vHPSD demonstrated a comparable safety profile to the other treatment arms. Procedural duration and energy application time was substantially reduced along with sedation requirement notwithstanding the limitations of observational study design, these preliminary findings are promising with respect to periprocedural outcomes and safety of vHPSD however longitudinal outcomes will be essential to assessing the overall efficacy of this novel technology. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Artificial intelligence for ventricular arrhythmia capability using ambulatory electrocardiograms

Author

Barker, Joseph, primary, Li, Xin, additional, Kotb, Ahmed, additional, Mavilakandy, Akash, additional, Antoun, Ibrahim, additional, Thaitirarot, Chokanan, additional, Koev, Ivelin, additional, Man, Sharon, additional, Sclindwein, Fernando S, additional, Dhutia, Harshil, additional, Chin, Shui Hao, additional, Tyukin, Ivan, additional, Nicolson, William B, additional, and Ng, G Andre, additional

Published
2023
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42. Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart

Author

Guevara, Amanda, primary, Smith, Charlotte E.R., additional, Caldwell, Jessica L., additional, Ngo, Lena, additional, Mott, Lilian R., additional, Lee, I-Ju, additional, Tapa, Srinivas, additional, Wang, Zhen, additional, Wang, Lianguo, additional, Woodward, William R., additional, Ng, G. André, additional, Habecker, Beth A., additional, and Ripplinger, Crystal M., additional

Published
2023
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44. Avalanches of Bose-Einstein Condensates in Leaking Optical Lattices

Author

Ng, G. S., Hennig, H., Fleischmann, R., Kottos, T., and Geisel, T.

Subjects
Condensed Matter - Statistical Mechanics, Condensed Matter - Other Condensed Matter, Nonlinear Sciences - Chaotic Dynamics
Abstract

One of the most fascinating experimental achievements of the last decade was the realization of Bose-Einstein Condensation (BEC) of ultra-cold atoms in optical lattices (OL's). The extraordinary level of control over these structures allows us to investigate complex solid state phenomena and the emerging field of ``atomtronics'' promises a new generation of nanoscale devices. It is therefore of fundamental and technological importance to understand their dynamical properties. Here we study the outgoing atomic flux of BECs loaded in an one-dimensional OL with leaking edges, using a mean field description provided by the Discrete Non-Linear Schrodinger Equation (DNLSE). We demonstrate that the atom population inside the OL decays in avalanches of size $J$. For intermediate values of the interatomic interaction strength their distribution ${\cal P}(J)$ follows a power law i.e. ${\cal P}(J)\sim1/J^{\alpha}$ characterizing systems at phase transition. This scale free behaviour of ${\cal P}(J)$ reflects the complexity and the hierarchical structure of the underlying classical mixed phase space. Our results are relevant in a variety of contexts (whenever DNLSE is adequate), most prominently the light emmitance from coupled non-linear optics waveguides., Comment: 7 pages and 3 figures

Published
2008
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49. Emotional Burnout Syndrome Among Physicians and Teachers of Higher Education

Author

NG G Petrova and OV V Murzenko

Subjects
burnout syndrome, doctors, nurses, teachers, Medicine
Abstract

The bumout syndrome is becoming increasingly important especially in the conditions of social and psychological tension in the society. Health workers and teachers are at very high risk of it’s possessing. Aim - the study of the severity of burnout syndrome among different categories of medical staff and teachers of higher education and the development of proposals for its prevention. Materials and methods. By the method of K. Maslach and S. Jackson using a special questionnaire the data on the burnout syndrome severity of such manifestation as emotional exhaustion in doctors, nurses (working in the city polyclinic, hospital, commercial medical organization) and teachers of the medical University was studied. The total number of examined persons is 100 people. Results and discussion. The low attrition rate was presented in 37.0% cases; medium - in 44.0%; high - in 19,0%. The most marked signs were determined as emotional exhaustion among persons under 40 years of age, with an experience of up to 10 years; among those working in a polyclinic, teachers and nurses. Conclusion. On the basis of the data obtained, the measures for the prevention of burnout syndrome were proposed.

Published
2018
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