97 results on '"Nexøe J"'
Search Results
2. Influence of number needed to treat, costs and outcome on preferences for a preventive drug
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Nexøe, J, Kristiansen, IS, Gyrd-Hansen, D, and Nielsen, JB
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- 2005
3. Willingness to pay for decreased indoor radon exposure - an analysis of framing and the decision process
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Nielsen, J. B., Dorte Gyrd-Hansen, Kristiansen, I. S., and Nexøe, J.
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- 2003
4. Problematisk mål for effekt
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Kristiansen, I. S., Christensen, P., Dorte Gyrd-Hansen, Nexøe, J., and Nielsen, J. B.
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- 2002
5. Number needed to treat:en statistisk kasuistik (korrespondance)
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Nexøe, J. and Kristiansen, I.S.
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- 2002
6. Effects of baseline-risk information on social and individual choices
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Gyrd-Hansen, D., Kristiansen, Ivar Sønbø, Nexøe, J., and Nielsen, Jesper Bo
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- 2002
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7. Er De forvirret?:Sundhedsdebatten 2002; 22
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Nexøe, J.
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- 2002
8. Number needed to treat: easily understood and intuitively meaningful?:Theoretical considerations and a randomized trial
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Kristiansen, Ivar Sønbø, Gyrd-Hansen, D., Nexøe, J., and Nielsen, J.B.
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- 2002
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9. Synspunkt:Influenzavaccinationer i Danmark
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Nexøe, J.
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- 2001
10. Influenzavaccination blandt ældre
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Nexøe. J.
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- 1999
11. Effekt af influenzavaccinationskampagnen i Københavns Kommune i saesonen 1996-1997
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Nexøe, J and Kragstrup, J
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Questionnaires ,Evaluation Studies as Topic ,Influenza Vaccines ,Risk Factors ,Denmark ,Influenza, Human ,Humans ,Health Promotion ,humanities ,Immunization Schedule ,Aged - Abstract
In Denmark influenza vaccinations are usually paid for by the patients. In the autumn of 1996 Copenhagen City Council offered free influenza vaccinations to all residents aged 70 years or older. The impact of the campaign was evaluated in a questionnaire study of a random sample of the Danish population aged 70 years or older. In Copenhagen 81% (95% Confidence interval: 67-95%) of the elderly at risk were vaccinated compared to 51% (45-56%) outside Copenhagen. Offering free influenza vaccinations in a mass campaign is an effective way of improving coverage rate. However, no substantial difference was found in cost between the mass campaign and a targeted campaign with free vaccination in general practice. Udgivelsesdato: 1998-Aug-17
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- 1998
12. Kvalitativ interview-undersøgelse om aeldres valg af influenzavaccination
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Nexøe, J
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Male ,Questionnaires ,Patient Education as Topic ,Influenza Vaccines ,Denmark ,Health Behavior ,Humans ,Patient Compliance ,Female ,Attitude to Health ,humanities ,Aged ,Haemophilus Vaccines - Abstract
Nine elderly men and women were interviewed in order to discover factors of importance in accepting influenza vaccinations. The study demonstrated that the fee to be paid by the patients was a considerable barrier to an improvement of the vaccination rate. The elderly informants were all aware that influenza vaccine is available. Some informants expressed uncertainty whether they themselves belonged to the risk groups who should be vaccinated. Sources of information were the general practitioner (GP), relatives, and the mass media. More personal information from the GP to persons at risk was wanted. Influenza vaccination behaviour was found to be consistent with the Health Belief Model. The present organization of influenza vaccinations does not promote a sufficient immunization rate. The threshold for accepting influenza vaccinations appears to be too high for the elderly population. Udgivelsesdato: 1998-Apr-20
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- 1998
13. Providing patients with their diagnostic test results. A vignette study in general practice
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Nexøe, J, Falk-Petersen, H E, Klit, Stefan, Larsen, N J, and Winthereik, M
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Adult ,Male ,Questionnaires ,Physician-Patient Relations ,Lung Neoplasms ,Communication ,Denmark ,HIV Seropositivity ,Humans ,Middle Aged ,Family Practice ,Truth Disclosure - Abstract
Udgivelsesdato: 1998-Apr-20 The communication of results of HIV tests and chest-X-rays because of persistent coughing are of particular interest because potential life-threatening disease may be disclosed. For HIV tests it is recommended that the result is communicated to the patient in the doctor's office face to face. In this questionnaire study based on two simulated case-stories with a 63 year-old man referred to chest-X-rays because of persistent coughing, and a 27 year-old man, who had been living in Africa for some time, now wanting a HIV test performed, we found that only half (53%) of the general practitioners (GP) did communicate HIV test results in the consultation office. X-ray test results were only communicated in the consultation office by 18% of the GPs. Communication of test results which might have serious implications to the patient should preferably not be done by telephone. Patients should be told of potentially serious results in person by their own physician.
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- 1998
14. Influenzavaccinationer i Danmark i sæsonen 1999-2000
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Nexøe, J., Kragstrup, J., Nexøe, J., and Kragstrup, J.
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Introduction: During the influenza season of 1999-2000, private vaccination clinics in Denmark increasingly offered influenza vaccination in competition with general practitioners (GPs). The clinics arranged group vaccinations in the local community or at workplaces at prices below the standard price. The aim of this study was to assess the actual proportion of people vaccinated, both in the elderly and in the younger population, and to elucidate the effect of marketing by the private vaccination clinics. Material and method: In February 2000, a questionnaire about influenza vaccination and general health was posted to 2,144 persons aged 65 or older and 1,717 aged 18-64 years randomly drawn from the Home Office Central Person Register. The questionnaire was completed by 70% in the older group and 66% in the younger group. Results: In Denmark, 47% of the older group and 8% of the younger group were vaccinated against influenza. In the municipality of Copenhagen the acceptance rate was 66% in the older group, compared to 46% in the rest of the country. General practitioners vaccinated 69% of the older group and 66% of the younger group, 24% were vaccinated at a vaccination clinic, and 7% were vaccinated elsewhere. Half the 18-64 year-olds were vaccinated by their own GP, 33% at their workplace, 11% at a vaccination clinic, and 6% elsewhere. Discussion: Based on this study, it is recommended that more effort is made to vaccinate young people in treatment for a chronic illness and the elderly against influenza. Influenza vaccination campaigns aimed at defined target groups could easily be done by general practitioners without establishing a new ad hoc organisation.
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- 2001
15. Influenzavaccinationer i Danmark i saesonen 1999-2000
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Nexøe, J, Kragstrup, J, Nexøe, J, and Kragstrup, J
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INTRODUCTION: During the influenza season of 1999-2000, private vaccination clinics in Denmark increasingly offered influenza vaccination in competition with general practitioners (GPs). The clinics arranged group vaccinations in the local community or at workplaces at prices below the standard price. The aim of this study was to assess the actual proportion of people vaccinated, both in the elderly and in the younger population, and to elucidate the effect of marketing by the private vaccination clinics.MATERIAL AND METHOD: In February 2000, a questionnaire about influenza vaccination and general health was posted to 2,144 persons aged 65 or older and 1,717 aged 18-64 years randomly drawn from the Home Office Central Person Register. The questionnaire was completed by 70% in the older group and 66% in the younger group.RESULTS: In Denmark, 47% of the older group and 8% of the younger group were vaccinated against influenza. In the municipality of Copenhagen the acceptance rate was 66% in the older group, compared to 46% in the rest of the country. General practitioners vaccinated 69% of the older group and 66% of the younger group, 24% were vaccinated at a vaccination clinic, and 7% were vaccinated elsewhere. Half the 18-64 year-olds were vaccinated by their own GP, 33% at their workplace, 11% at a vaccination clinic, and 6% elsewhere.DISCUSSION: Based on this study, it is recommended that more effort is made to vaccinate young people in treatment for a chronic illness and the elderly against influenza. Influenza vaccination campaigns aimed at defined target groups could easily be done by general practitioners without establishing a new ad hoc organisation.
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- 2001
16. Decision on influenza vaccination among the elderly. A questionnaire study based on the Health Belief Model and the Multidimensional Locus of Control Theory
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Nexøe, J, Kragstrup, J, Søgaard, J, Nexøe, J, Kragstrup, J, and Søgaard, J
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OBJECTIVE: To create an empirical model, describing factors of importance to the elderly in accepting influenza vaccinations.DESIGN: Epidemiologic study with two coupled questionnaires. In September 1996 a 46-item questionnaire was sent to 2147 elderly people (> or = 65 years). The questionnaire comprised questions about general health, and questions based on the Health Belief Model and the Multidimensional Locus of Control Theory. In February 1997 a postcard questionnaire was sent to the same elderly people asking whether they had been vaccinated against influenza in the past season.SETTING: All Danish counties.SUBJECTS: 2147 persons randomly sampled from the The Civil Registration System.MAIN OUTCOME MEASURE: Factors influencing the rate of influenza vaccine uptake in the elderly. Influenza vaccination rates.RESULTS: In the high-risk group 51% (95% confidence interval: 46-55%) were vaccinated compared to 29% (26-32%) in the low-risk group as regards influenza. By logistic regression the Health Belief Model dimensions "perceived barriers", "perceived benefits" and "perceived severity" were found to be significant predictors of acceptance of influenza vaccinations.CONCLUSIONS: An empirical model based on the Health Belief Model predicting acceptance of influenza vaccinations with a positive predictive value of 91% (87-94%) and a negative predictive value of 86% (83-88%) was obtained.
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- 1999
17. INDOOR RADON EXPOSURE: AN ANALYSIS OF WILLINGNESS-TO-PAY AND THE DECISION PROCESS
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Nielsen, J B., primary, Gyrd-Hansen, D, additional, Kristiansen, I S., additional, and Nexøe, J, additional
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- 2004
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18. Willingness to pay for decreased indoor radon exposure: an analysis of framing and the decision process
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NIELSEN, J. B., primary, GYRD-HANSEN, D., additional, KRISTIANSEN, I. S., additional, and NEXØE, J., additional
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- 2003
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19. Betydning af indkaldelse og brugerbetaling for influenzavaccination blandt aeldre. Et randomiseret kontrolleret forsøg i almen praksis
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Nexøe, J, Kragstrup, J, Rønne, T, Nexøe, J, Kragstrup, J, and Rønne, T
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Influenza epidemics are accompanied by considerable excess morbidity and mortality especially among the elderly and the chronically ill. In the influenza season 1995 a controlled, randomized trial was carried out to examine the impact of postal invitations and user fee on influenza vaccination rates. Five hundred and eighty-five patients aged 65 years or older participated. They were all recognized by their general practitioner (GP) to be in the risk group to whom influenza vaccination is recommended. One third were invited to free influenza vaccination. Another third received postal invitations to influenza vaccination paying the usual fee ($40-$60 US). The last third served as a control group, being vaccinated on their own request and paying the usual fee. In the control group 25% (19-31%, 95% confidence interval) of the patients were vaccinated, compared to 49% (42-56%) in the group which received a postal reminder and paid the usual fee, and 72% (65-78%) in the group invited to be vaccinated free of charge.
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- 1997
20. Impact of postal invitations and user fee on influenza vaccination rates among the elderly. A randomized controlled trial in general practice
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Nexøe, J, Kragstrup, J, Rønne, T, Nexøe, J, Kragstrup, J, and Rønne, T
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OBJECTIVE: To examine the impact of postal invitations and user fee on influenza vaccination rates.DESIGN: A controlled randomized trial in 13 general practices. One third of the participating patients received postal invitations to influenza vaccination free of charge. Another third received postal invitations to influenza vaccination on paying the usual fee (US$ 40-60). The last third served as a control group, being vaccinated at their own request and paying the usual fee.SETTING: General practice in the Counties of Funen and Vejle, Denmark.PATIENTS: Five hundred and eighty-five patients aged 65 years or older, recognized by their general practitioner (GP) as being in the risk group for whom influenza vaccination is recommended.MAIN OUTCOME MEASURES: Influenza vaccination rates.RESULTS: In the control group 25% (19-31%, 95% confidence interval) of the patients were vaccinated, compared with 49% (42-56%) in the group who received a postal reminder and paid the usual fee, and 72% (65-78%) in the group invited to be vaccinated free of charge.CONCLUSION: It is suggested that GPs send postal invitations to their elderly patients in the risk groups urgently recommending influenza vaccination. Attention should also be given to offering free influenza vaccination to elderly patients who have recognized indications for vaccination.
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- 1997
21. Measurement of blood pressure, ankle blood pressure and calculation of ankle brachial index in general practice.
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Nexøe J, Damsbo B, Lund JO, and Munck A
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- 2012
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22. Medication effectiveness may not be the major reason for accepting cardiovascular preventive medication: A population-based survey
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Harmsen Charlotte, Støvring Henrik, Jarbøl Dorte, Nexøe Jørgen, Gyrd-Hansen Dorte, Nielsen Jesper, Edwards Adrian, and Kristiansen Ivar
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Decision-making ,Risk assessment ,Risk communication ,Preventive health services ,Primary prevention ,Cardiovascular disease ,Health behavior ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Background Shared decision-making and patients’ choice of interventions are areas of increasing importance, not least seen in the light of the fact that chronic conditions are increasing, interventions considered important for public health, and still non-acceptance of especially risk-reducing treatments of cardiovascular diseases (CVD) is prevalent. A better understanding of patients’ medication-taking behavior is needed and may be reached by studying the reasons why people accept or decline medication recommendations. The aim of this paper was to identify factors that may influence people’s decisions and reasoning for accepting or declining a cardiovascular preventive medication offer. Methods From a random sample of 4,000 people aged 40–59 years in a Danish population, 1,169 participants were asked to imagine being at increased risk of cardiovascular disease and being offered a preventive medication. After receiving ‘complete’ information about effectiveness of the medication they were asked whether they would accept medication. Finally, they were asked about reasons for the decision. Results A total of 725 (67%) of 1,082 participants accepted the medication offer. Even quite large effects of medication (up to 8 percentage points absolute risk reduction) had a smaller impact on acceptance to medication than personal experience with cardiovascular disease. Furthermore, increasing age of the participant and living with a partner were significantly associated with acceptance. Some 45% of the respondents accepting justified their choice as being for health reasons, and they were more likely to be women, live alone, have higher income and higher education levels. Among those who did not accept the medication offer, 56% indicated that they would rather prefer to change lifestyle. Conclusions Medication effectiveness seems to have a moderate influence on people’s decisions to accept preventive medication, while factors such as personal experience with cardiovascular disease may have an equally strong or stronger influence, indicating that practitioners could do well to carefully identify the reasons for their patients’ treatment decisions.
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- 2012
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23. Laypersons' understanding of relative risk reductions: Randomised cross-sectional study
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Kristiansen Ivar S, Gyrd-Hansen Dorte, Sorensen Lene, Nexøe Jørgen, and Nielsen Jesper B
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Background Despite increasing recognition of the importance of involving patients in decisions on preventive healthcare interventions, little is known about how well patients understand and utilise information provided on the relative benefits from these interventions. The aim of this study was to explore whether lay people can discriminate between preventive interventions when effectiveness is presented in terms of relative risk reduction (RRR), and whether such discrimination is influenced by presentation of baseline risk. Methods The study was a randomised cross-sectional interview survey of a representative sample (n = 1,519) of lay people with mean age 59 (range 40–98) years in Denmark. In addition to demographic information, respondents were asked to consider a hypothetical drug treatment to prevent heart attack. Its effectiveness was randomly presented as RRR of 10, 20, 30, 40, 50 or 60 percent, and half of the respondents were presented with quantitative information on the baseline risk of heart attack. The respondents had also been asked whether they were diagnosed with hypercholesterolemia or had experienced a heart attack. Results In total, 873 (58%) of the respondents consented to the hypothetical treatment. While 49% accepted the treatment when RRR = 10%, the acceptance rate was 58–60% for RRR>10. There was no significant difference in acceptance rates across respondents irrespective of whether they had been presented with quantitative information on baseline risk or not. Conclusion In this study, lay people's decisions about therapy were only slightly influenced by the magnitude of the effect when it was presented in terms of RRR. The results may indicate that lay people have difficulties in discriminating between levels of effectiveness when they are presented in terms of RRR.
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- 2008
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24. Communicating effectiveness of intervention for chronic diseases: what single format can replace comprehensive information?
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Kristiansen Ivar S, Gyrd-Hansen Dorte, Stovring Henrik, Nexoe Jorgen, and Nielsen Jesper B
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Background There is uncertainty about how GPs should convey information about treatment effectiveness to their patients in the context of cardiovascular disease. Hence we study the concordance of decisions based on one of four single information formats for treatment effectiveness with subsequent decisions based on all four formats combined with a pictorial representation. Methods A randomized study comprising 1,169 subjects aged 40–59 in Odense, Denmark. Subjects were randomized to receive information in terms of absolute risk reduction (ARR), relative risk reduction (RRR), number needed to treat (NNT), or prolongation of life (POL) without heart attack, and were asked whether they would consent to treatment. Subsequently the same information was conveyed with all four formats jointly accompanied by a pictorial presentation of treatment effectiveness. Again, subjects should consider consent to treatment. Results After being informed about all four formats, 52%–79% of the respondents consented to treatment, depending on level of effectiveness and initial information format. Overall, ARR gave highest concordance, 94% (95% confidence interval (91%; 97%)) between initial and final decision, but ARR was not statistically superior to the other formats. Conclusion Decisions based on ARR had the best concordance with decisions based on all four formats and pictorial representation, but the difference in concordance between the four formats was small, and it is unclear whether respondents fully understood the information they received.
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- 2008
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25. Can postponement of an adverse outcome be used to present risk reductions to a lay audience? A population survey
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Kristiansen Ivar, Gyrd-Hansen Dorte, Dahl Rasmus, Nexøe Jørgen, and Bo Nielsen Jesper
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Background For shared decision making doctors need to communicate the effectiveness of therapies such that patients can understand it and discriminate between small and large effects. Previous research indicates that patients have difficulties in understanding risk measures. This study aimed to test the hypothesis that lay people may be able to discriminate between therapies when their effectiveness is expressed in terms of postponement of an adverse disease event. Methods In 2004 a random sample of 1,367 non-institutionalized Danes aged 40+ was interviewed in person. The participants were asked for demographic information and asked to consider a hypothetical preventive drug treatment. The respondents were randomized to the magnitude of treatment effectiveness (heart attack postponement of 1 month, 6 months, 12 months, 2 years, 4 years and 8 years) and subsequently asked whether they would take such a therapy. They were also asked whether they had hypercholesterolemia or had experienced a heart attack. Results In total 58% of the respondents consented to the hypothetical treatment. The proportions accepting treatment were 39%, 52%, 56%, 64%, 67% and 73% when postponement was 1 month, 6 months, 12 months, 2 years, 4 years and 8 years respectively. Participants who thought that the effectiveness information was difficult to understand, were less likely to consent to therapy (p = 0.004). Conclusion Lay people can discriminate between levels of treatment effectiveness when they are presented in terms of postponement of an adverse event. The results indicate that such postponement is a comprehensible measure of effectiveness.
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- 2007
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26. NNT is not easily understood
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Kristiansen, I.S., Nexøe, J., Gyrd-Hansen, D., and Nielsen, J.B.
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- 2002
27. Gatekeeping and referral of patients holding private health insurance: a survey among general practitioners in Norway.
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Breivold J, Isaksson Rø K, Nilsen S, Andersen MKK, Nexøe J, and Hjörleifsson S
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- Humans, Norway, Female, Male, Cross-Sectional Studies, Middle Aged, Adult, Surveys and Questionnaires, Attitude of Health Personnel, Private Sector, Practice Patterns, Physicians', General Practice, Logistic Models, Medical Overuse, Referral and Consultation, General Practitioners, Insurance, Health, Gatekeeping
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Objective: Private health insurance is becoming more common in Norway. The aim of this study was to investigate GPs' opinions on private health insurance, and their experiences from consultations where health insurance can affect decisions about referring., Design: A web based cross-sectional survey., Setting: Norwegian general practice., Subjects: All GPs in Norway were in 2019 invited to participate in an online survey., Main Outcome Measures: The GPs' opinions and experiences regarding health insurance were reported as proportions. Multiple logistic regression was used to test associations between how frequently GPs refer patients without further considerations and variables concerning their characteristics, opinions, and experiences., Results: Of 1,309 GPs (response rate 27%), 93% stated that private health insurance raises the risk of overtreatment and 90% considered such insurance to contribute to inequality in health. Frequently being pressured to refer in the absence of a medical indication was reported by 42%. Moreover, 28% often or always chose to refer patients without further consideration, and this was associated with perceptions of pressure with an adjusted odds ratio (AOR) of 3.80, 95% confidence interval (CI) 2.73-5.29, and unpleasant reactions from patients following refusals (AOR 1.63, 95% CI 1.14-2.33)., Conclusion: Although most participating GPs associated private health insurance with overtreatment and inequality in health, more than one in four choose to refer without further consideration. GPs' experience of pressure to refer and negative reactions from patients when they consider referrals not to be medically indicated, raises the risk of medical overuse for patients holding private health insurance.
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- 2024
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28. Scientific papers and artificial intelligence. Brave new world?
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Nexøe J
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- 2023
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29. Factors associated with statin discontinuation near end of life in a Danish primary health care cohort.
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Engell AE, Bathum L, Andersen JS, Thompson W, Lind BS, Jørgensen HL, and Nexøe J
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- Humans, Retrospective Studies, Primary Health Care, Denmark, Death, Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use
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Background: Long-term preventive treatment such as treatment with statins should be reassessed among patients approaching end of life. The aim of the study was to describe the rate of discontinuation of statin treatment and factors associated with discontinuation in the 6 months before death., Methods: This study is a retrospective cohort study using national registers and blood test results from primary health care patients. Patients in the Copenhagen municipality, Denmark who died between 1997 and 2018 and were statin users during the 10-year period before death were included. We calculated the proportion who remained statin users in the 6-month period before death. Factors associated with discontinuation were tested using logistic regression., Results: A total of 55,591 decedents were included. More patients continued treatment (64%, n = 35,693) than discontinued (36%, n = 19,898) the last 6 months of life. The 70 and 80 age groups had the lowest odds of discontinuing compared to the 90 (OR 1.59, 95% CI 0.93-2.72) and 100 (OR 3.11, 95% CI 2.79-3.47) age groups. Increasing comorbidity score (OR 0.89, 95% CI 0.87; 0.90 per 1-point increase) and use of statins for secondary prevention (OR 0.89, 95% CI 0.85; 0.93) reduced the likelihood of discontinuation as did a diagnosis of dementia, heart failure, or cancer., Conclusion: A substantial portion of patients continued statin treatment near end of life. Efforts to promote rational statin use and discontinuation are required among patients with limited life expectancy, including establishing clear, practical recommendations about statin discontinuation, and initiatives to translate recommendations into clinical practice., (© The Author(s) 2022. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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- 2023
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30. Health alliance for prudent prescribing and yield of antibiotics in a patient-centred perspective (HAPPY PATIENT): a before-and-after intervention and implementation study protocol.
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Bjerrum A, García-Sangenís A, Modena D, Córdoba G, Bjerrum L, Chalkidou A, Lykkegaard J, Hansen MP, Søndergaard J, Nexøe J, Rebnord I, Sebjørnsen I, Jensen JN, Hansen MB, Taxis K, Lambert M, Benko R, González López-Valcárcel B, Raynal F, Barragán N, Touboul P, Bruno P, Radzeviciene R, Jaruseviciene L, Bandzaite A, Godycki-Cwirko M, Kowalczyk A, Lionis C, Karkana MN, Anastasaki M, Coleman J, Glasová H, van Agtmael M, Tattevin P, Borràs A, and Llor C
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- Anti-Bacterial Agents therapeutic use, Drug Resistance, Microbial, Humans, Insurance Pools, Community-Acquired Infections drug therapy, Respiratory Tract Infections drug therapy
- Abstract
Background: Excessive and inappropriate use of antibiotics is the most important driver of antimicrobial resistance. The aim of the HAPPY PATIENT project is to evaluate the adaptation of European Union (EU) recommendations on the prudent use of antimicrobials in human health by evaluating the impact of a multifaceted intervention targeting different categories of healthcare professionals (HCPs) on common community-acquired infectious diseases, especially respiratory and urinary tract infections., Methods/design: HAPPY PATIENT was initiated in January 2021 and is planned to end in December 2023. The partners of this project include 15 organizations from 9 countries. Diverse HCPs (doctors, nurses, pharmacists, and pharmacy technicians) will be audited by the Audit Project Odense (APO) method before and after an intervention in four different settings: general practice, out of hours services, nursing homes and community pharmacies in four high antibiotic prescribing countries (France, Poland, Greece, and Spain) and one low prescribing country (Lithuania). About 25 individuals from each professional group will be recruited in each country, who will register at least 25 patients with community-acquired infections during each audit period. Shortly before the second registration participants will undertake a multifaceted intervention and will receive the results from the first registration to allow the identification of possible quality problems. At these meetings participants will receive training courses on enhancement of communication skills, dissemination of clinical guidelines with recommendations for diagnosis and treatment, posters for the waiting rooms, and leaflets for patients. The results of the second registration will be compared with those obtained in the first audit., Discussion: HAPPY PATIENT is an EU-funded project aimed at contributing to the battle against antibiotic resistance through improvement of the quality of management of common community-acquired infections based on interventions by different types of HCPs. It is hypothesized that the use of multifaceted strategies combining active intervention will be effective in reducing inappropriate prescribing and dispensing of antibiotics., Study Registration: EU Health programmes project database https://webgate.ec.europa.eu/chafea_pdb/health/projects/900024/summary ; date of registration: 1 January 2021., (© 2022. The Author(s).)
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- 2022
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31. #MeToo - second wave a concern in health care, general practice included.
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Nexøe J
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- Delivery of Health Care, Family Practice, Health Facilities, Humans, General Practice, Sex Offenses
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- 2021
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32. Insomnia in the elderly: reported reasons and their associations with medication in general practice in Denmark.
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Hollsten I, Foldbo BM, Kousgaard Andersen MK, and Nexøe J
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- Aged, Aged, 80 and over, Comorbidity, Denmark, Female, Humans, Logistic Models, Male, Odds Ratio, Prevalence, Benzodiazepines adverse effects, Benzodiazepines therapeutic use, Drug Prescriptions, General Practice, General Practitioners, Hypnotics and Sedatives adverse effects, Hypnotics and Sedatives therapeutic use, Practice Patterns, Physicians', Sleep Initiation and Maintenance Disorders drug therapy, Sleep Initiation and Maintenance Disorders etiology
- Abstract
Objective: The aim of this study was to investigate reasons for insomnia symptoms and their associations with sleep medication prescription in elderly patients in general practice. Design: Over a period of 20 weekdays, general practitioners (GPs) recorded reasons and treatment for insomnia symptoms. Patient characteristics and outcomes were analysed using descriptive statistics. Logistic regression was used to analyse the associations between reasons for insomnia symptoms and prescription. Setting: General practices in the Region of Southern Denmark. Subjects: Consultations ( n = 405) with patients older than 65 years presenting with insomnia symptoms. Main outcome measures: Reasons for insomnia symptoms and sleep medication prescription. Results: The most commonly reported reasons for insomnia symptoms were somatic illness (34%) and psychiatric diagnosis (29%). Having a psychiatric diagnosis or multiple reported reasons for insomnia increased the odds for prescription (odds ratio (OR) 4.60, 95% confidence interval (CI) 2.41-9.90 and OR 2.10, CI 1.03-4.28), whereas being first consultation regarding insomnia symptoms decreased the odds (OR 0.17, CI 0.10-0.30). A total of 80% received a prescription, most frequently of Z-hypnotics (49%). About half (52%) of the patients consulting their GP for the first time with insomnia symptoms received a prescription. Conclusion: Somatic and psychiatric diseases were the most commonly reported reasons for insomnia symptoms in the elderly, suggesting a high prevalence of comorbid insomnia. Regardless of reason, a majority of the consultations resulted in prescription of sleep medication with potential serious adverse effects. This indicates that there is still room for improving the management of insomnia among older adults. Key Points Although insomnia is common in the elderly, little is known about its reasons and their associations with prescription patterns. The most commonly reported reasons for insomnia symptoms in the elderly are psychiatric diagnosis and somatic illness. According to guidelines, sleep medication with potential serious adverse effects is prescribed too frequently to elderly patients. An effort should be made to identify and optimally treat comorbid insomnia, which appears to be prevalent in older adults.
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- 2020
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33. Danish general practice under threat?
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Nexøe J
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- Denmark, Health Policy, General Practice, Medically Underserved Area
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- 2019
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34. Cross-cultural adaptation of the medical engagement scale into Danish general practice setting.
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Ahnfeldt-Mollerup P, Riisgaard H, Søndergaard J, and Nexøe J
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- Culture, Denmark, General Practice, Humans, Translating, United Kingdom, Family Practice, General Practitioners, Leadership, Primary Health Care, Surveys and Questionnaires, Work Engagement
- Abstract
Introduction: The need to involve doctors in healthcare leadership has long been recognized by clinical staff and policymakers. A Medical Engagement Scale has been designed in England to evaluate levels of medical engagement in leadership and management. Objective: The aim of this study was to translate and adapt the scale and to test the translated version for comprehension and suitability in Danish general practice setting. Design and method: The process involved forward translation, backward translation, and field tests. The field tests included cognitive debriefing interviews. In all 30 general practitioners and 5 non-general practitioners participated in the process of translation. After using the scale among 1652 general practitioners statistical analysis was carried out to test internal consistency. Setting: The study was carried out in general practice in Denmark. Results: Several changes made during the process in order to achieve a Danish version that is acceptable, understandable and still capable of measuring medical engagement comparable of the original English version. Analysis of scale internal consistency using Cronbach's alpha revealed acceptable reliability for all three meta-scales, which ranged from 0.69 to 0.81. The overall tool achieved a Cronbach's alpha of 0.89. Conclusion: The Danish version of the Medical Engagement Scale is a valid and reliable tool that is acceptable and relevant for general practice in Denmark. Key points This study describes the cross-cultural adaptation of the Medical Engagement Scale from a UK primary healthcare setting to a Danish primary healthcare setting. The process produced a relevant and acceptable questionnaire measuring medical engagement. Internal consistency revealed acceptable reliability The translation of the scale provides the possibility to use this scale for practical and academic purposes.
- Published
- 2019
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35. Defensive medicine in primary health care.
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Lykkegaard J, Andersen MKK, Nexøe J, and Hvidt EA
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- Attitude of Health Personnel, Denmark, Hospitals, Humans, Italy, Jurisprudence, Primary Health Care, Defensive Medicine, Documentation, Medical Records, Physicians, Practice Patterns, Physicians' legislation & jurisprudence
- Published
- 2018
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36. Variation in Point-of-Care Testing of HbA1c in Diabetes Care in General Practice.
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Kristensen T, Waldorff FB, Nexøe J, Skovsgaard CV, and Olsen KR
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- Adult, Age Factors, Aged, Aged, 80 and over, Denmark, Female, Humans, Male, Middle Aged, Prevalence, Sex Factors, Socioeconomic Factors, Young Adult, Diabetes Mellitus, Type 1 blood, Diabetes Mellitus, Type 2 blood, General Practice statistics & numerical data, Glycated Hemoglobin analysis, Point-of-Care Testing statistics & numerical data, Practice Patterns, Physicians' statistics & numerical data
- Abstract
Background: Point-of-care testing (POCT) of HbA1c may result in improved diabetic control, better patient outcomes, and enhanced clinical efficiency with fewer patient visits and subsequent reductions in costs. In 2008, the Danish regulators created a framework agreement regarding a new fee-for-service fee for the remuneration of POCT of HbA1c in general practice. According to secondary research, only the Capital Region of Denmark has allowed GPs to use this new incentive for POCT. The aim of this study is to use patient data to characterize patients with diabetes who have received POCT of HbA1c and analyze the variation in the use of POCT of HbA1c among patients with diabetes in Danish general practice. Methods: We use register data from the Danish Drug Register, the Danish Health Service Register and the National Patient Register from the year 2011 to define a population of 44,981 patients with diabetes (type 1 and type 2 but not patients with gestational diabetes) from the Capital Region. The POCT fee is used to measure the amount of POCT of HbA1c among patients with diabetes. Next, we apply descriptive statistics and multilevel logistic regression to analyze variation in the prevalence of POCT at the patient and clinic level. We include patient characteristics such as gender, age, socioeconomic markers, health care utilization, case mix markers, and municipality classifications. Results: The proportion of patients who received POCT was 14.1% and the proportion of clinics which were "POCT clinics" was 26.9%. There were variations in the use of POCT across clinics and patients. A part of the described variation can be explained by patient characteristics. Male gender, age differences (older age), short education, and other ethnicity imply significantly higher odds for POCT. High patient costs in general practice and other parts of primary care also imply higher odds for POCT. In contrast, high patient costs for drugs and/or morbidity in terms of the Charlson Comorbidity index mean lower odds for POCT. The frequency of patients with diabetes per 1000 patients was larger in POCT clinics than Non-POCT clinics. A total of 22.5% of the unexplained variability was related to GP clinics. Conclusions: This study demonstrates variation in the use of POCT which can be explained by patient characteristics such as demographic, socioeconomic, and case mix markers. However, it appears relevant to reassess the system for POCT. Further studies are warranted in order to assess the impacts of POCT of HbA1c on health care outcomes., Competing Interests: The authors declare no conflict of interest.
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- 2017
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37. General practitioners' attitudes towards and experiences with referrals due to supplemental health insurance.
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Andersen MK, Pedersen LB, Dupont M, Pedersen KM, Munck A, and Nexøe J
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- Adult, Aged, Denmark, Female, Health Status Disparities, Humans, Male, Middle Aged, Practice Patterns, Physicians' statistics & numerical data, Surveys and Questionnaires, Attitude of Health Personnel, General Practitioners psychology, Insurance, Health statistics & numerical data, Referral and Consultation statistics & numerical data
- Abstract
Background: Supplemental health insurances (SHI) cover 38% of the Danish population. SHI can give faster access to, and additional treatment from, private health providers. However, this is contingent on a referral from the general practitioner (GP), further complicating clinical decision-making., Objectives: To describe GPs' attitudes to SHI and their experiences with patients holding SHI. Moreover, we analysed associations between different GP characteristics; e.g. gender, age, practice type, own SHI status and their attitudes to and experiences with SHI., Methods: A questionnaire was mailed to 3321 GPs focusing on three issues: (i) Attitudes towards the public health care system. (ii) Perceptions of the impact of SHI. (iii) Experiences with patients holding SHIs., Results: The response rate was 64%. Overall, GPs found that SHIs contribute to inequality (83%) and overtreatment (90%). However, 46% often feel under pressure to refer SHI patients to specialist care, even though not medically indicated, while 11% always or often refer SHI patients unconditionally. Both groups perceive SHI patients more insistent on getting referrals than patients without SHI., Conclusion: Even though a majority of GPs associate SHI with overtreatment and inequality in health, many GPs feel under pressure to refer patients holding SHI for treatments or examinations that are not medically warranted. Some GPs even refer these patients without further examination or questioning. Insistent SHI patients may partly explain this paradox. Future research should illuminate SHI patients' courses in the private as well as the public healthcare system with regards to medical indications and health outcome measures focusing on inequality and overtreatment., (© The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2017
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38. Successful task delegation in general practice - a way to maintain primary health care in the future.
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Riisgaard H and Nexøe J
- Subjects
- Denmark, Forecasting, General Practice organization & administration, General Practice trends, General Practitioners, Humans, Primary Health Care methods, Delegation, Professional methods, Delegation, Professional organization & administration, Delegation, Professional trends, General Practice methods, Primary Health Care trends
- Published
- 2017
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39. Are formalised implementation activities associated with aspects of quality of care in general practice? A cross-sectional study.
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Le JV, Lykkegaard J, Pedersen LB, Riisgaard H, Nexøe J, Lemmergaard J, and Søndergaard J
- Abstract
Background: There is a substantial variation in how different general practices manage knowledge implementation, including the degree to which activities are collectively and formally organised. Yet, it is unclear how these differences in implementation activities affect quality of care., Aim: To investigate if there are associations between specific formalised knowledge implementation activities and quality of care in general practices, exemplified by the use of spirometry testing., Design & Setting: A nationwide cross-sectional study combining survey and register data in Denmark., Method: An electronic questionnaire was distributed to GPs, and data on spirometry testing among first-time users of medication against obstructive lung diseases were obtained from national registers. Associations were investigated using multilevel mixed-effect logit models., Results: GPs from 1114 practices (58%) responded, and 33 788 patients were linked to a responding practice. In partnership practices, the frequency of interdisciplinary and GP meetings affected the quality of care. Interdisciplinary and GP meetings held on a weekly basis were significantly associated with a higher level of quality of care and this was measured by the odds ratio (OR) of patients having spirometry. The development of practice protocols and standard recordings in the electronic medical record (EMR) for a range of disease areas compared with few or no areas at all also impacted the quality of care level provided. The effect of formalised implementation activities was not as evident in single-handed practices as in partnerships., Conclusion: This study provides valuable knowledge for GPs who aim to organise their practice in a way that supports implementation and quality improvement most effectively. Also, results may be useful for managers of implementation strategies and quality improvement initiatives when planning future activities., Competing Interests: The authors declare that no competing interests exist.
- Published
- 2017
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40. Work motivation, task delegation and job satisfaction of general practice staff: a cross-sectional study.
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Riisgaard H, Søndergaard J, Munch M, Le JV, Ledderer L, Pedersen LB, and Nexøe J
- Subjects
- Adult, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Pulmonary Disease, Chronic Obstructive therapy, Surveys and Questionnaires, General Practice, Health Personnel psychology, Job Satisfaction, Motivation, Task Performance and Analysis
- Abstract
Background: Recent research has shown that a high degree of task delegation is associated with the practise staff's overall job satisfaction, and this association is important to explore since job satisfaction is related to medical as well as patient-perceived quality of care., Objectives: This study aimed: (1) to investigate associations between degrees of task delegation in the management of chronic disease in general practice, with chronic obstructive pulmonary disease (COPD) as a case and the staff's work motivation, (2) to investigate associations between the work motivation of the staff and their job satisfaction., Methods: The study was based on a questionnaire to which 621 members of the practice staff responded. The questionnaire consisted of a part concerning degree of task delegation in the management of COPD in their respective practice and another part being about their job satisfaction and motivation to work., Results: In the first analysis, we found that 'maximal degree' of task delegation was significantly associated with the staff perceiving themselves to have a large degree of variation in tasks, odds ratio (OR) = 4.26, confidence interval (CI) = 1.09, 16.62. In the second analysis, we found that this perceived large degree of variation in tasks was significantly associated with their overall job satisfaction, OR = 2.81, confidence interval = 1.71, 4.61., Conclusion: The results suggest that general practitioners could delegate highly complex tasks in the management of COPD to their staff without influencing the staff's work motivation, and thereby their job satisfaction, negatively, as long as they ensure sufficient variation in the tasks., (© The Author 2017. Published by Oxford University Press.)
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- 2017
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41. Associations between degrees of task delegation and job satisfaction of general practitioners and their staff: a cross-sectional study.
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Riisgaard H, Søndergaard J, Munch M, Le JV, Ledderer L, Pedersen LB, and Nexøe J
- Subjects
- Adult, Aged, Cross-Sectional Studies, Family Practice, Female, General Practice, Humans, Male, Middle Aged, Perception, Pulmonary Disease, Chronic Obstructive, Surveys and Questionnaires, Workplace, Delegation, Professional, General Practitioners psychology, Job Satisfaction, Workload psychology
- Abstract
Background: In recent years, the healthcare system in the western world has undergone a structural development caused by changes in demography and pattern of disease. In order to maintain the healthcare system cost-effective, new tasks are placed in general practice urging the general practitioners to rethink the working structure without compromising the quality of care. However, there is a substantial variation in the degree to which general practitioners delegate tasks to their staff, and it is not known how these various degrees of task delegation influence the job satisfaction of general practitioners and their staff., Methods: We performed a cross-sectional study based on two electronic questionnaires, one for general practitioners and one for their staff. Both questionnaires were divided into two parts, a part exploring the degree of task delegation regarding management of patients with chronic obstructive pulmonary disease in general practice and a part concerning the general job satisfaction and motivation to work., Results: We found a significant association between perceived "maximal degree" of task delegation in management of patients with chronic obstructive pulmonary disease and the staff's overall job satisfaction. The odds ratio of the staff's satisfaction with the working environment displayed a tendency that there is also an association with "maximal degree" of task delegation. In the analysis of the general practitioners, the odds ratios of the results indicate that there is a tendency that "maximal degree" of task delegation is associated with overall job satisfaction, satisfaction with the challenges in work, and satisfaction with the working environment., Conclusions: We conclude that a high degree of task delegation is significantly associated with overall job satisfaction of the staff, and that there is a tendency that a high degree of task delegation is associated with the general practitioners' and the staff's satisfaction with the working environment as well as with general practitioners' overall job satisfaction and satisfaction with challenges in work. To qualify future delegation processes within general practice, further research could explore the reasons for our findings.
- Published
- 2017
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42. Variation in general practitioners' information-seeking behaviour - a cross-sectional study on the influence of gender, age and practice form.
- Author
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Le JV, Pedersen LB, Riisgaard H, Lykkegaard J, Nexøe J, Lemmergaard J, and Søndergaard J
- Subjects
- Adult, Age Factors, Aged, Cross-Sectional Studies, Denmark, Evidence-Based Practice, Female, General Practice, Humans, Male, Middle Aged, Sex Factors, Surveys and Questionnaires, Attitude of Health Personnel, Family Practice, General Practitioners, Information Seeking Behavior, Practice Patterns, Physicians'
- Abstract
Objective: To assess general practitioners' (GPs') information-seeking behaviour and perceived importance of sources of scientific medical information and to investigate associations with GP characteristics., Design: A national cross-sectional survey was distributed electronically in December 2013., Setting: Danish general practice., Subjects: A population of 3440 GPs (corresponding to approximately 96% of all Danish GPs)., Main Outcome Measures: GPs' use and perceived importance of information sources. Multilevel mixed-effects logit models were used to investigate associations with GP characteristics after adjusting for relevant covariates., Results: A total of 1580 GPs (46.4%) responded to the questionnaire. GPs' information-seeking behaviour is associated with gender, age and practice form. Single-handed GPs use their colleagues as an information source significantly less than GPs working in partnership practices and they do not use other sources more frequently. Compared with their younger colleagues, GPs aged above 44 years are less likely to seek information from colleagues, guidelines and websites, but more likely to seek information from medical journals. Male and female GPs seek information equally frequently. However, whereas male GPs are more likely than female GPs to find that pharmaceutical sales representative and non-refundable CME meetings are important, they are less likely to find that colleagues, refundable CME meetings, guidelines and websites are important., Conclusion: Results from this study indicate that GP characteristics should be taken into consideration when disseminating scientific medical information, to ensure that patients receive medically updated, high-quality care. KEY POINTS Research indicates that information-seeking behaviour is associated with GP characteristics. Further insights could provide opportunities for targeting information dissemination strategies. Single-handed GPs seek information from colleagues less frequently than GPs in partnerships and do not use other sources more frequently. GPs aged above 44 years do not seek information as frequently as their younger colleagues and prefer other information sources. Male and female GPs seek information equally frequently, but do not consider information sources equally important in keeping medically updated.
- Published
- 2016
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- View/download PDF
43. Relations between task delegation and job satisfaction in general practice: a systematic literature review.
- Author
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Riisgaard H, Nexøe J, Le JV, Søndergaard J, and Ledderer L
- Subjects
- Administrative Personnel psychology, Attitude of Health Personnel, Humans, Nurses psychology, Physicians psychology, General Practice organization & administration, Job Satisfaction, Professional Role psychology
- Abstract
Background: It has for years been discussed whether practice staff should be involved in patient care in general practice to a higher extent. The research concerning task delegation within general practice is generally increasing, but the literature focusing on its influence on general practitioners' and their staff's job satisfaction appears to be sparse even though job satisfaction is acknowledged as an important factor associated with both patient satisfaction and medical quality of care. Therefore, the overall aim of this study was 1) to review the current research on the relation between task delegation and general practitioners' and their staff's job satisfaction and, additionally, 2) to review the evidence of possible explanations for this relation., Methods: A systematic literature review. We searched the four databases PubMed, Cinahl, Embase, and Scopus systematically. The immediate relevance of the retrieved articles was evaluated by title and abstract by the first author, and papers that seemed to meet the aim of the review were then fully read by first author and last author independently judging the eligibility of content., Results: We included four studies in the review. They explored views and attitudes of the staff, encompassing nurses as well as practice managers. Only one of the included studies also explored general practitioners' views and attitudes, hence making it impossible to establish any syntheses on this relation. According to the studies, the staff's overall attitude towards task delegation was positive and led to increased job satisfaction, probably because task delegation comprised a high degree of work autonomy., Conclusions: The few studies included in our review suggest that task delegation within general practice may be seen by the staff as an overall positive issue contributing to their job satisfaction, primarily due to perceived autonomy in the work. However, because of the small sample size comprising only qualitative studies, and due to the heterogeneity of these studies, we cannot draw unambiguous conclusions although we point towards tendencies.
- Published
- 2016
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44. Medical engagement and organizational characteristics in general practice.
- Author
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Ahnfeldt-Mollerup P, dePont Christensen R, Halling A, Kristensen T, Lykkegaard J, Nexøe J, Barwell F, Spurgeon P, and Søndergaard J
- Subjects
- Adult, Age Factors, Aged, Cross-Sectional Studies, Denmark, Female, Humans, Male, Middle Aged, Sex Factors, Surveys and Questionnaires, General Practice organization & administration, General Practitioners, Leadership, Quality Improvement
- Abstract
Background: Medical engagement is a mutual concept of the active and positive contribution of doctors to maintaining and enhancing the performance of their health care organization, which itself recognizes this commitment in supporting and encouraging high quality care. A Medical Engagement Scale (MES) was developed by Applied Research Ltd (2008) on the basis of emerging evidence that medical engagement is critical for implementing radical improvements., Objectives: To study the importance of medical engagement in general practice and to analyse patterns of association with individual and organizational characteristics., Design and Setting: A cross-sectional study using a sampled survey questionnaire and the official register from the Danish General Practitioners' Organization comprising all registered Danish GPs., Method: The Danish version of the MES Questionnaire was distributed and the survey results were analysed in conjunction with the GP register data., Results: Statistically adjusted analyses revealed that the GPs' medical engagement varied substantially. GPs working in collaboration with colleagues were more engaged than GPs from single-handed practices, older GPs were less engaged than younger GPs and female GPs had higher medical engagement than their male colleagues. Furthermore, GPs participating in vocational training of junior doctors were more engaged than GPs not participating in vocational training., Conclusion: Medical engagement in general practice varies a great deal and this is determined by a complex interaction between both individual and organizational characteristics. Working in collaboration, having staff and being engaged in vocational training of junior doctors are all associated with enhanced levels of medical engagement among GPs., (© The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2016
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45. Preference for practice--recent evidence.
- Author
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Bjørnskov Pedersen L and Nexøe J
- Subjects
- Denmark, Humans, Professional Practice Location, Workforce, General Practice, General Practitioners supply & distribution, Rural Health Services
- Published
- 2016
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46. How GPs implement clinical guidelines in everyday clinical practice--a qualitative interview study.
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Le JV, Hansen HP, Riisgaard H, Lykkegaard J, Nexøe J, Bro F, and Søndergaard J
- Subjects
- Adult, Attitude of Health Personnel, Denmark, Family Practice standards, Female, Humans, Interviews as Topic, Male, Middle Aged, Practice Patterns, Physicians', Qualitative Research, General Practitioners, Guideline Adherence, Practice Guidelines as Topic
- Abstract
Background: Clinical guidelines are considered to be essential for improving quality and safety of health care. However, interventions to promote implementation of guidelines have demonstrated only partial effectiveness and the reasons for this apparent failure are not yet fully understood., Objective: To investigate how GPs implement clinical guidelines in everyday clinical practice and how implementation approaches differ between practices., Methods: Individual semi-structured open-ended interviews with seven GPs who were purposefully sampled with regard to gender, age and practice form. Interviews were recorded, transcribed verbatim and then analysed using systematic text condensation., Results: Analysis of the interviews revealed three different approaches to the implementation of guidelines in clinical practice. In some practices the GPs prioritized time and resources on collective implementation activities and organized their everyday practice to support these activities. In other practices GPs discussed guidelines collectively but left the application up to the individual GP whilst others again saw no need for discussion or collective activities depending entirely on the individual GP's decision on whether and how to manage implementation., Conclusion: Approaches to implementation of clinical guidelines vary substantially between practices. Supporting activities should take this into account., (© The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2015
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47. As you are a recognized expert in this field, we kindly ask if you would be willing to review this manuscript.
- Author
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Nexøe J
- Subjects
- Humans, Journalism, Medical, Publishing standards, Editorial Policies, Peer Review, Research standards
- Published
- 2014
- Full Text
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48. Communicating risk using absolute risk reduction or prolongation of life formats: cluster-randomised trial in general practice.
- Author
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Harmsen CG, Kristiansen IS, Larsen PV, Nexøe J, Støvring H, Gyrd-Hansen D, Nielsen JB, Edwards A, and Jarbøl DE
- Subjects
- Adult, Aged, Cluster Analysis, Denmark, Female, General Practice, Humans, Male, Middle Aged, Prospective Studies, Risk Assessment, Surveys and Questionnaires, Cardiovascular Diseases prevention & control, Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use, Hypercholesterolemia drug therapy, Life Support Care, Numbers Needed To Treat
- Abstract
Background: It is important that patients are well-informed about risks and benefits of therapies to help them decide whether to accept medical therapy. Different numerical formats can be used in risk communication but It remains unclear how the different formats affect decisions made by real-life patients., Aim: To compare the impact of using Prolongation Of Life (POL) and Absolute Risk Reduction (ARR) information formats to express effectiveness of cholesterol-lowering therapy on patients' redemptions of statin prescriptions, and on patients' confidence in their decision and satisfaction with the risk communication., Design and Setting: Cluster-randomised clinical trial in general practices. Thirty-four Danish GPs from 23 practices participated in a primary care-based clinical trial concerning use of quantitative effectiveness formats for risk communication in health prevention consultations., Method: GPs were cluster-randomised (treating practices as clusters) to inform patients about cardiovascular mortality risk and the effectiveness of statin treatment using either POL or ARR formats. Patients' redemptions of statin prescriptions were obtained from a regional prescription database. The COMRADE questionnaire was used to measure patients' confidence in their decision and satisfaction with the risk communication., Results: Of the 240 patients included for analyses, 112 were allocated to POL information and 128 to ARR. Patients redeeming a statin prescription totalled six (5.4%) when informed using POL, and 32 (25.0%) when using ARR. The level of confidence in decision and satisfaction with risk communication did not differ between the risk formats., Conclusion: Patients redeemed statin prescriptions less often when their GP communicated treatment effectiveness using POL compared with ARR.
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- 2014
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49. A competing risk approach for the European Heart SCORE model based on cause-specific and all-cause mortality.
- Author
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Støvring H, Harmsen CG, Wisløff T, Jarbøl DE, Nexøe J, Nielsen JB, and Kristiansen IS
- Subjects
- Adult, Age Factors, Aged, Biomarkers blood, Blood Pressure, Cause of Death, Cholesterol blood, Coronary Disease blood, Coronary Disease diagnosis, Coronary Disease physiopathology, Coronary Disease therapy, Dyslipidemias blood, Dyslipidemias drug therapy, Dyslipidemias mortality, Europe epidemiology, Female, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use, Hypertension mortality, Hypertension physiopathology, Male, Middle Aged, Models, Statistical, Risk Assessment, Risk Factors, Sex Factors, Smoking adverse effects, Smoking mortality, Time Factors, Coronary Disease mortality, Decision Support Techniques
- Abstract
Background: The European Heart SCORE model constitutes the basis for national guidelines for primary prevention and treatment of cardiovascular disease (CVD) in several European countries. The model estimates individuals' 10-year CVD mortality risks from age, sex, smoking status, systolic blood pressure, and total cholesterol level. The SCORE model, however, is not mathematically consistent and does not estimate all-cause mortality. Our aim is to modify the SCORE model to allow consistent estimation of both CVD-specific and all-cause mortality., Methods: Using a competing risk approach, we first re-estimated the cause-specific risk of dying from cardiovascular disease, and secondly we incorporated non-CVD mortality. Finally, non-CVD mortality was allowed to also depend on smoking status, and not only age and sex. From the models, we estimated CVD-specific and all-cause 10-year mortality risk, and the expected residual lifetime together with corresponding expected effects of statin treatment., Results: The modified model provided CVD-specific 10-year mortality risks similar to those of the European Heart SCORE model. Incorporation of non-CVD mortality increased 10-year mortality risks, in particular for older individuals. When non-CVD mortality was assumed unaffected by smoking status, the absolute risk reduction due to statin treatment ranged from 0.0% to 3.5%, whereas the gain in expected residual lifetime ranged from 3 to 11 months. Statin effectiveness increased for non-smokers and declined for smokers, when smoking was allowed to influence non-CVD mortality., Conclusion: The modified model provides mathematically consistent estimates of mortality risk and expected residual lifetime together with expected benefits from statin treatment.
- Published
- 2013
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50. Developing Danish general practice.
- Author
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Nexøe J
- Subjects
- Denmark, Family Practice, Humans, Workload, General Practice legislation & jurisprudence, General Practice organization & administration, Health Services Accessibility
- Published
- 2013
- Full Text
- View/download PDF
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