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3. How Can I Recover Commercial Rent Arrears? Part 1

Author

Newton, Florence

Subjects
Commercial leases -- Laws, regulations and rules, Rents (Property) -- Laws, regulations and rules, Government regulation, Business, international
Abstract

What is Commercial Rent Arrears Recovery ('CRAR') and When Can I Use It? Commercial Rent Arrears Recovery (otherwise known as 'CRAR') was introduced in April 2014 by virtue of Part [...]

Published
2022

6. Scleroderma and related disorders: 223. Long Term Outcome in a Contemporary Systemic Sclerosis Cohort

Author

Nihtyanova, Svetlana, Ong, Voon, Black, Carol, Denton, Chris, Lutalo, Pamela, Shattles, Warren, Jones, Hugh, Nouri, Reem, Hepburn, Alastair, Chard, Michael, Horwood, Natalie, Lynn, Myo, Duke, Oliver, Kiely, Patrick, Zouita, Louisa, Davies, Ursula, Hughes, Rod, Lloyd, Mark, Nikitorowicz Buniak, Joanna, Shiwen, Xu, Abraham, David, Stratton, Richard, Hügle, Thomas, Schuetz, Philipp, Daikeler, Thomas, Tyndall, Alan, Matucci-Cerinic, Marco, Walker, Ulrich A., van Laar, Jacob M., Pauling, John D., Flower, Victoria, McHugh, Neil, Liu, Shangxi, Leask, Andrew, Aden, Nima, Khan, Korsa, Hoyles, Rachel, Bhagat, Shweta, Drummond, Tom, Goh, Cyndi, Busch, Robert, Hall, Frances, Meyer, Paul, Moinzadeh, Pia, Krieg, Thomas, Hellmich, Martin, Brinckmann, Juergen, Neumann, Elena, Mueller-Ladner, Ulf, Kreuter, Alexander, Dumitresco, Daniel, Rosenkranz, Stefan, Hunzelmann, Nicolas, Binai, Nadine, Huegle, Thomas, van Laar, Jaap, Sonnylal, S., Tam, A., Jones, H., Leask, A., Norman, J., Denton, C., de Crombrugghe, B., Abraham, D., Chighizola, Cecilia B., Luigi Meroni, Pier, Coghlan, Gerry, Newton, Florence, Derrett-Smith, Emma C., Dooley, Audrey, Baliga, Reshma, Hobbs, Adrian, MacAllister, Raymond, Futema, Marta, Pantelidis, Panagiotis, Renzoni, Elizabeth, Schreiber, Benjamin E., Coghlan, Gerry J., Wells, Athol U., Welsh, Ken, Fonseca, Carmen, Ponticos, Markella, Wells, Athol, Guillevin, Loic, Schwierin, Barbara, Rosenberg, Daniel, Silkey, Mariabeth, Parapuram, Sunil, Shi-wen, Xu, Denton, Christopher, Ahmed Abdi, Bahja, Xu, Shiwen, Nihtyanova, Svetlana, Ong, Voon, Black, Carol, Denton, Chris, Lutalo, Pamela, Shattles, Warren, Jones, Hugh, Nouri, Reem, Hepburn, Alastair, Chard, Michael, Horwood, Natalie, Lynn, Myo, Duke, Oliver, Kiely, Patrick, Zouita, Louisa, Davies, Ursula, Hughes, Rod, Lloyd, Mark, Nikitorowicz Buniak, Joanna, Shiwen, Xu, Abraham, David, Stratton, Richard, Hügle, Thomas, Schuetz, Philipp, Daikeler, Thomas, Tyndall, Alan, Matucci-Cerinic, Marco, Walker, Ulrich A., van Laar, Jacob M., Pauling, John D., Flower, Victoria, McHugh, Neil, Liu, Shangxi, Leask, Andrew, Aden, Nima, Khan, Korsa, Hoyles, Rachel, Bhagat, Shweta, Drummond, Tom, Goh, Cyndi, Busch, Robert, Hall, Frances, Meyer, Paul, Moinzadeh, Pia, Krieg, Thomas, Hellmich, Martin, Brinckmann, Juergen, Neumann, Elena, Mueller-Ladner, Ulf, Kreuter, Alexander, Dumitresco, Daniel, Rosenkranz, Stefan, Hunzelmann, Nicolas, Binai, Nadine, Huegle, Thomas, van Laar, Jaap, Sonnylal, S., Tam, A., Jones, H., Leask, A., Norman, J., Denton, C., de Crombrugghe, B., Abraham, D., Chighizola, Cecilia B., Luigi Meroni, Pier, Coghlan, Gerry, Newton, Florence, Derrett-Smith, Emma C., Dooley, Audrey, Baliga, Reshma, Hobbs, Adrian, MacAllister, Raymond, Futema, Marta, Pantelidis, Panagiotis, Renzoni, Elizabeth, Schreiber, Benjamin E., Coghlan, Gerry J., Wells, Athol U., Welsh, Ken, Fonseca, Carmen, Ponticos, Markella, Wells, Athol, Guillevin, Loic, Schwierin, Barbara, Rosenberg, Daniel, Silkey, Mariabeth, Parapuram, Sunil, Shi-wen, Xu, Denton, Christopher, Ahmed Abdi, Bahja, and Xu, Shiwen

Abstract

Background: We have previously compared outcome in two groups of systemic sclerosis (SSc) patients with disease onset a decade apart and we reported data on 5 year survival and cumulative incidence of organ disease in a contemporary SSc cohort. The present study examines longer term outcome in an additional cohort of SSc followed for 10 years. Methods: We have examined patients with disease onset between years 1995 and 1999 allowing for at least 10 years of follow-up in a group that has characteristics representative for the patients we see in contemporary clinical practice. Results: Of the 398 patients included in the study, 252 (63.3%) had limited cutaneous (lc) SSc and 146 (36.7%) had diffuse cutaneous (dc) SSc. The proportion of male patients was higher among the dcSSc group (17.1% v 9.9%, p = 0.037) while the mean age of onset was significantly higher among lcSSc patients (50 ± 13 v 46 ± 13 years ± SD, p = 0.003). During a 10 year follow-up from disease onset, 45% of the dcSSc and 21% of the lcSSc subjects developed clinically significant pulmonary fibrosis, p < 0.001. Among them approximately half reached the endpoint within the first 3 years (23% of dcSSc and 10% of lcSSc) and over three quarters within the first 5 years (34% and 16% respectively). There was a similar incidence of pulmonary hypertension (PH) in the two subsets with a steady rate of increase over time. At 10 years 13% of dcSSc and 15% of lcSSc subjects had developed PH (p=0.558), with the earliest cases observed within the first 2 years of disease. Comparison between subjects who developed PH in the first and second 5 years from disease onset demonstrated no difference in demographic or clinical characteristics, but 5-year survival from PH onset was better among those who developed this complication later in their disease (49% v 24%), with a strong trend towards statistical significance (p = 0.058). Incidence of SSc renal crisis (SRC) was significantly higher among the dcSSc patients (12% v 4%

Published
2017

8. Florence Huntington Newton Bookplate

Author

Stone, Wilbur Macey, Messenger, Maria Gerard, 1849-1937, Newton, Florence Huntington, Stone, Wilbur Macey, Messenger, Maria Gerard, 1849-1937, and Newton, Florence Huntington

Abstract

Pictorial bookplate, inscribed: "Florence Huntington Newton's book \ Date [blank]". Depicts text with a stack of books at the top. The artist's initials and the year are visible in the bottom-left and right corners, respectively.

Published
1899

9. Scleroderma and related disorders: 223. Long Term Outcome in a Contemporary Systemic Sclerosis Cohort

Author

Nihtyanova, Svetlana, Ong, Voon, Black, Carol, Denton, Chris, Lutalo, Pamela, Shattles, Warren, Jones, Hugh, Nouri, Reem, Hepburn, Alastair, Chard, Michael, Horwood, Natalie, Lynn, Myo, Duke, Oliver, Kiely, Patrick, Zouita, Louisa, Davies, Ursula, Hughes, Rod, Lloyd, Mark, Nikitorowicz Buniak, Joanna, Shiwen, Xu, Abraham, David, Stratton, Richard, Hügle, Thomas, Schuetz, Philipp, Daikeler, Thomas, Tyndall, Alan, Matucci-Cerinic, Marco, Walker, Ulrich A., van Laar, Jacob M., Pauling, John D., Flower, Victoria, McHugh, Neil, Liu, Shangxi, Leask, Andrew, Aden, Nima, Khan, Korsa, Hoyles, Rachel, Bhagat, Shweta, Drummond, Tom, Goh, Cyndi, Busch, Robert, Hall, Frances, Meyer, Paul, Moinzadeh, Pia, Krieg, Thomas, Hellmich, Martin, Brinckmann, Juergen, Neumann, Elena, Mueller-Ladner, Ulf, Kreuter, Alexander, Dumitresco, Daniel, Rosenkranz, Stefan, Hunzelmann, Nicolas, Binai, Nadine, Huegle, Thomas, van Laar, Jaap, Sonnylal, S., Tam, A., Jones, H., Leask, A., Norman, J., Denton, C., de Crombrugghe, B., Abraham, D., Chighizola, Cecilia B., Luigi Meroni, Pier, Coghlan, Gerry, Newton, Florence, Derrett-Smith, Emma C., Dooley, Audrey, Baliga, Reshma, Hobbs, Adrian, MacAllister, Raymond, Futema, Marta, Pantelidis, Panagiotis, Renzoni, Elizabeth, Schreiber, Benjamin E., Coghlan, Gerry J., Wells, Athol U., Welsh, Ken, Fonseca, Carmen, Ponticos, Markella, Wells, Athol, Guillevin, Loic, Schwierin, Barbara, Rosenberg, Daniel, Silkey, Mariabeth, Parapuram, Sunil, Shi-wen, Xu, Denton, Christopher, Ahmed Abdi, Bahja, Xu, Shiwen, Nihtyanova, Svetlana, Ong, Voon, Black, Carol, Denton, Chris, Lutalo, Pamela, Shattles, Warren, Jones, Hugh, Nouri, Reem, Hepburn, Alastair, Chard, Michael, Horwood, Natalie, Lynn, Myo, Duke, Oliver, Kiely, Patrick, Zouita, Louisa, Davies, Ursula, Hughes, Rod, Lloyd, Mark, Nikitorowicz Buniak, Joanna, Shiwen, Xu, Abraham, David, Stratton, Richard, Hügle, Thomas, Schuetz, Philipp, Daikeler, Thomas, Tyndall, Alan, Matucci-Cerinic, Marco, Walker, Ulrich A., van Laar, Jacob M., Pauling, John D., Flower, Victoria, McHugh, Neil, Liu, Shangxi, Leask, Andrew, Aden, Nima, Khan, Korsa, Hoyles, Rachel, Bhagat, Shweta, Drummond, Tom, Goh, Cyndi, Busch, Robert, Hall, Frances, Meyer, Paul, Moinzadeh, Pia, Krieg, Thomas, Hellmich, Martin, Brinckmann, Juergen, Neumann, Elena, Mueller-Ladner, Ulf, Kreuter, Alexander, Dumitresco, Daniel, Rosenkranz, Stefan, Hunzelmann, Nicolas, Binai, Nadine, Huegle, Thomas, van Laar, Jaap, Sonnylal, S., Tam, A., Jones, H., Leask, A., Norman, J., Denton, C., de Crombrugghe, B., Abraham, D., Chighizola, Cecilia B., Luigi Meroni, Pier, Coghlan, Gerry, Newton, Florence, Derrett-Smith, Emma C., Dooley, Audrey, Baliga, Reshma, Hobbs, Adrian, MacAllister, Raymond, Futema, Marta, Pantelidis, Panagiotis, Renzoni, Elizabeth, Schreiber, Benjamin E., Coghlan, Gerry J., Wells, Athol U., Welsh, Ken, Fonseca, Carmen, Ponticos, Markella, Wells, Athol, Guillevin, Loic, Schwierin, Barbara, Rosenberg, Daniel, Silkey, Mariabeth, Parapuram, Sunil, Shi-wen, Xu, Denton, Christopher, Ahmed Abdi, Bahja, and Xu, Shiwen

Abstract

Background: We have previously compared outcome in two groups of systemic sclerosis (SSc) patients with disease onset a decade apart and we reported data on 5 year survival and cumulative incidence of organ disease in a contemporary SSc cohort. The present study examines longer term outcome in an additional cohort of SSc followed for 10 years. Methods: We have examined patients with disease onset between years 1995 and 1999 allowing for at least 10 years of follow-up in a group that has characteristics representative for the patients we see in contemporary clinical practice. Results: Of the 398 patients included in the study, 252 (63.3%) had limited cutaneous (lc) SSc and 146 (36.7%) had diffuse cutaneous (dc) SSc. The proportion of male patients was higher among the dcSSc group (17.1% v 9.9%, p = 0.037) while the mean age of onset was significantly higher among lcSSc patients (50 ± 13 v 46 ± 13 years ± SD, p = 0.003). During a 10 year follow-up from disease onset, 45% of the dcSSc and 21% of the lcSSc subjects developed clinically significant pulmonary fibrosis, p < 0.001. Among them approximately half reached the endpoint within the first 3 years (23% of dcSSc and 10% of lcSSc) and over three quarters within the first 5 years (34% and 16% respectively). There was a similar incidence of pulmonary hypertension (PH) in the two subsets with a steady rate of increase over time. At 10 years 13% of dcSSc and 15% of lcSSc subjects had developed PH (p=0.558), with the earliest cases observed within the first 2 years of disease. Comparison between subjects who developed PH in the first and second 5 years from disease onset demonstrated no difference in demographic or clinical characteristics, but 5-year survival from PH onset was better among those who developed this complication later in their disease (49% v 24%), with a strong trend towards statistical significance (p = 0.058). Incidence of SSc renal crisis (SRC) was significantly higher among the dcSSc patients (12% v 4%

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