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12 results on '"Neupane, Manisha"'

3. Evaluation of Antioxidant and Anti-Inflammatory Activities, and Metabolite Profiling of Selected Medicinal Plants of Nepal

Author

Shrivastava, Amit Kumar, primary, Keshari, Muskan, additional, Neupane, Manisha, additional, Chaudhary, Sheshbhan, additional, Dhakal, Purna Kala, additional, Shrestha, Laxmi, additional, Palikhey, Anjan, additional, Yadav, Chandrajeet Kumar, additional, Lamichhane, Gopal, additional, Shekh, Mohammad Ujair, additional, and Yadav, Rakesh Kumar, additional

Published
2023
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10. GIANT CELLS AND GIANT CELL LESIONS OF ORAL CAVITY- A REVIEW

Author

SHRESTHA, Ashish, MARLA, Vinay, SHRESTHA, Sushmita, and NEUPANE, Manisha

Subjects
Pathology, medicine.medical_specialty, Monocyte, Biology, Oral cavity, Multinucleate, Tissue remodeling, medicine.anatomical_structure, Touton giant cell, Giant cell, giant cell lesions of oral cavity,monocytes,multinucleated giant cells, medicine, Immunohistochemistry, General Dentistry
Abstract

Giant cells are large mononucleated or multinucleated cells that are seen in a variety of physiological as well as pathological conditions. Multinucleated giant cells (MGCs) are important mediators of tissue remodeling and repair and also for removal of foreign materials and various pathogens. The commonly encountered giant cells arise from monocyte precursors, formed due to different mechanisms. Depending upon the mechanism of their formation these cells assume distinctly variable phenotypes. The giant cell lesions of oral cavity have been classified on the basis of etio-pathogenesis, the presence of which at times being pathognomic. We attempt to review the basic information regarding the mechanism of formation and morphology of giant cells and its significance in the associated giant cell lesions. Also we have tried to describe the clinical, histopathological and immunohistochemical aspects of various giant cell lesions of the oral cavity.

Published
2014

11. Optimization of Growth Conditions and Biological Activities of Nepalese Ganoderma lucidum Strain Philippine

Author

Subedi, Krishna, Bahadur Basnet, Buddha, Panday, Raju, Neupane, Manisha, and Raj Tripathi, Giri

Abstract

Ganoderma lucidum has been extensively studied for its valuable medicinal importance. In this study, the artificial cultivation of G. lucidum strain Philippine in different culture media, including sawdust substrate, was performed and optimized on the Potato Dextrose Agar (PDA) media. Phytochemical, antibacterial, and antioxidant analyses were performed and compared between the ethanol extracts prepared from two different cultures (fruit from synthetic log culture and mycelia from PDA media culture). Both the 200 mg/mL and 100 mg/mL concentrations of extracts inhibited all the tested bacteria, and the results were promising than the corresponding control using antibiotics. The fruit extract showed higher antioxidant potential (150.6 ± 56.92 mg ascorbic acid equivalent/g extract) than mycelial extract (144.28 ± 81.72 mg ascorbic acid equivalent/g extract). The results indicate that fruiting bodies of G. lucidum cultivated in a complex dust medium possess higher antioxidant properties than mycelia culture, which can be further explored for therapeutic applications.

Published
2021
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12. Periodontal Lesions among Maxillary Sinus Mucosal Thickening Visiting the Department of Oral Medicine and Radiology of a Tertiary Care Centre.

Author

Bali H, Neupane M, Mahanta SK, Niroula D, Upadhyaya C, and Kafle D

Subjects
Male, Humans, Adult, Middle Aged, Aged, Female, Cross-Sectional Studies, Tertiary Care Centers, Cone-Beam Computed Tomography methods, Maxillary Sinus diagnostic imaging, Maxillary Sinus pathology, Radiology
Abstract

Introduction: Maxillary sinus due to its proximity to posterior maxillary teeth could be affected by their pathology. Since cone beam computed tomography is the go-to for 3-D imaging in dental set-up. This study aimed to find out the prevalence of periodontal lesions among maxillary sinus mucosal thickening visiting the Department of Oral Medicine and Radiology of a tertiary care centre., Methods: This descriptive cross-sectional study was conducted in the Department of Oral Medicine and Radiology of a tertiary care centre from 01 February 2021 to 30 June 2021 after obtaining ethical approval from the Institutional Review Committee. The medical records from 01 January 2019 to 31 December 2019 were retrieved. The identification of maxillary sinus mucosal thickening of more than 3 mm, in cone beam computed tomography images, was registered separately for the right and left sinuses of each patient. The presence of periodontal lesions of posterior teeth was recorded. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval., Results: Among 195 maxillary sinus mucosal thickening, periodontal lesions were found in 74 (37.95%) (31.14-44.76, 95% Confidence Interval) maxillary sinuses of 46 patients. The mean age was 53.67±12.72 years and 30 (65.21%) were males., Conclusions: The prevalence of periodontal lesions among maxillary sinus mucosal thickening in CBCT images was similar to other studies done in similar settings., Keywords: cone beam computed tomography; maxillary sinus; periodontal disease; prevalence.

Published
2024
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