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19 results on '"Nesbitt, Robin C."'

2. Vaccination coverage and adverse events following a reactive vaccination campaign against hepatitis E in Bentiu displaced persons camp, South Sudan

Author

Nesbitt, Robin C., primary, Asilaza, Vincent Kinya, additional, Gignoux, Etienne, additional, Koyuncu, Aybüke, additional, Gitahi, Priscillah, additional, Nkemenang, Patrick, additional, Duncker, Jetske, additional, Antier, Zelie, additional, Haile, Melat, additional, Gakima, Primitive, additional, Wamala, Joseph F., additional, Loro, Fredrick Beden, additional, Biem, Duol, additional, Rull, Monica, additional, Azman, Andrew S., additional, Rumunu, John, additional, and Ciglenecki, Iza, additional

Published
2024
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4. Vaccination coverage and adverse events following a reactive vaccination campaign against hepatitis E in Bentiu displaced persons camp, South Sudan

Author

Nesbitt, Robin C, primary, Asilaza, Vincent Kinya, additional, Gignoux, Etienne, additional, Koyuncu, Aybüke, additional, Gitahi, Priscillah, additional, Nkemenang, Patrick, additional, Duncker, Jetske, additional, Antier, Zelie, additional, Haile, Melat, additional, Gakima, Primitive, additional, Wamala, Joseph F, additional, Loro, Frederick Beden, additional, Biem, Duol, additional, Rull, Monica, additional, Azman, Andrew S, additional, Rumunu, John, additional, and Ciglenecki, Iza, additional

Published
2023
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5. Retention on ART and predictors of disengagement from care in several alternative community-centred ART refill models in rural Swaziland

Author

Pasipamire, Lorraine, Nesbitt, Robin C, Ndlovu, Sindiso, Sibanda, Gibson, Mamba, Sipho, Lukhele, Nomthandazo, Pasipamire, Munyaradzi, Kabore, Serge M, Rusch, Barbarba, Ciglenecki, Iza, and Kerschberger, Bernhard

Subjects
HIV infections -- Risk factors -- Drug therapy -- Diagnosis, Antiretroviral agents -- Dosage and administration, Health
Abstract

Introduction: A broad range of community-centred care models for patients stable on anti-retroviral therapy (ART) have been proposed by the World Health Organization to better respond to patient needs and alleviate pressure on health systems caused by rapidly growing patient numbers. Where available, often a single alternative care model is offered in addition to routine clinical care. We operationalized several community-centred ART delivery care models in one public sector setting. Here, we compare retention in care and on ART and identify predictors of disengagement with care. Methods: Patients on ART were enrolled into three community-centred ART delivery care models in the rural Shiselweni region (Swaziland), from 02/2015 to 09/2016: Community ART Groups (CAGs), comprehensive outreach care and treatment clubs. We used Kaplan-Meier estimates to describe crude retention in care model and retention on ART (including patients who returned to clinical care). Multivariate Cox proportional hazard models were used to determine factors associated with all-cause attrition from care model and disengagement with ART. Results: A total of 918 patients were enrolled. CAGs had the most participants with 531 (57.8%). Median age was 44.7 years (IQR 36.3 to 54.4), 71.8% of patients were female, and 62.6% fulfilled eligibility criteria for community ART. The 12-month retention in ART was 93.7% overall; it was similar between model types (p = 0.52). A considerable proportion of patients returned from community ART to clinical care, resulting in lower 12 months retention in care model (82.2% overall); retention in care model was lowest in CAGs at 70.4%, compared with 86.3% in outreach and 90.4% in treatment clubs (p < 0.001). In multivariate Cox regression models, patients in CAGs had a higher risk of disengaging from care model (aHR 3.15, 95% CI 2.01 to 4.95, p < 0.001) compared with treatment clubs. We found, however, no difference in attrition in ART between alternative model types. Conclusions: Concurrent implementation of three alternative community-centred ART models in the same region was feasible. Although a considerable proportion of patients returned back to clinical care, overall ART retention was high and should encourage programme managers to offer community-centred care models adapted to their specific setting. Keywords: HIV care continuum; community; retention; differentiated care; Swaziland; models of community ART delivery, 1 | INTRODUCTION Swaziland, the country with the highest HIV prevalence in the world (30.5% in adults aged 18 to 49 years) [1], adopted the World Health Organization (WHO) 'treat-all' [...]

Published
2018
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8. Implementation of community and facility‐based HIV self‐testing under routine conditions in southern Eswatini

Author

Pasipamire, Lorraine, primary, Nesbitt, Robin C., additional, Dube, Lenhle, additional, Mabena, Edwin, additional, Nzima, Muzi, additional, Dlamini, Mduduzi, additional, Rugongo, Nozizwe, additional, Maphalala, Nomthandazo, additional, Obulutsa, Thomas Austin, additional, Ciglenecki, Iza, additional, and Kerschberger, Bernhard, additional

Published
2020
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9. Nutrients and perinatal depression: a systematic review

Author

Sparling, Thalia M, Nesbitt, Robin C, Henschke, Nicholas, and Gabrysch, Sabine

Subjects
LMIC, low-income and middle-income countries, EPDS, Edinburgh Postpartum Depression Scale, RCT, randomised controlled trial, Systematic Review, Nutrients, Maternal health, Perinatal depression, CES-D, Center for Epidemiological Studies Depression Scale, Nutritional biomarkers
Abstract

Pregnancy and lactation deplete nutrients essential to the neurotransmission system. This may be one reason for the increased risk of depression during the perinatal period. The objective of the present review was to systematically review the literature and summarise evidence on whether blood nutrient levels influence the risk of perinatal depression. PubMed, EMBASE and CINAHL databases were searched for studies of any design. A total of twenty-four articles of different designs were included, representing 14 262 subjects. We extracted data on study population, depression prevalence, nutrients examined, deficiency prevalence, timing of assessment, reporting, analysis strategy and adjustment factors. In all, fourteen studies found associations of perinatal depression with lower levels of folate, vitamin D, Fe, Se, Zn, and fats and fatty acids, while two studies found associations between perinatal depression and higher nutrient levels, and eight studies found no evidence of an association. Only ten studies had low risk of bias. Given the methodological limitations and heterogeneity of study approaches and results, the evidence for a causal link between nutritional biomarkers and perinatal depression is still inconclusive. High-quality studies in deficient populations are needed.

Published
2017

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