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As more and more couples face infertility, one of the most challenging causes is represented by endometriosis. Latest studies have shown that more that 10% of reproductive-aged women suffer from endometriosis. The pathogenesis of endometriosis can offer some insight for what exactly the mechanism for infertility is. The management of the patient include a specific balance between pain management, fertility management and quality of life improvement. The aim of this presentation is to discuss the current approaches to endometriosisrelated infertility, especially in severe endometriosis in need for extensive surgery. [ABSTRACT FROM AUTHOR]

It is well known that ovarian cancer is one of the most severe forms of cancer in women, with high mortality and morbidity. Ovarian cancers can be classified in type I and II. There are almost 100 years from the first discussion regarding the relationship between endometriosis and ovarian cancer, stated by Sampson in 1927. Current studies have observed that the prevalence of ovarian cancer varies between 0.7% and 17% in women with endometriosis. The pathogenetic process of endometriosis as cancer precursor was understood with the help of molecular medicine and genetics. The aim of this presentation is to summarize the current knowledge on endometriosis-related ovarian cancers. Understanding the pathologies can help to better select the patients with endometriosis who need further screening for ovarian cancer [ABSTRACT FROM AUTHOR]

Introduction. Keratotic lesions are a common encounter in the genital area in the practice of gynecologists or dermatologists. Making a precise diagnosis can be challenging, but it is critical for treatment and prognosis. In these instances, a dermoscopic examination is particularly useful because it is a quick, inexpensive, noninvasive and sensitive examination. However, dermoscopic data comparing bowenoid papulosis (BP), seborrheic keratosis (SK) and condyloma acuminatum (CA) is still lacking. More than 40 different genotypes of HPV infect the vaginal area and cause diverse intraepithelial neoplasms. Materials and method. We propose to exemplify the differences of the three diagnostics – BP, genital SK and CA – by describing their dermatoscopic characteristics and the relation with the HPV infection. Results. Dermoscopic findidings: BP has glomerular vessels, CA has hairpin vessels, and SK has the smallest vascular pattern. The SK has a cerebriform look, while the CA has a knob-like or finger-like shape with a whitish halo. HPV DNA detection is positive in both BP and CA, while studies suggest that more than half of SK have positive HPV findings. BP has the highest detection rate for high-risk genotypes, mostly HPV 16, and CA has the highest detection rate for low-risk genotypes, primarily HPV 6 and HPV-11. Conclusions. Before resorting to an invasive procedure, dermoscopy can help distinguish the entity of genital keratotic lesions, and a physician should examine the morphologic plasticity of HPVrelated keratosis in the genital area or the genital wart in the enlarged notion. [ABSTRACT FROM AUTHOR]

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