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181 results on '"Nelder, Mark P"'

1. Age- and Sex-Specific Differences in Lyme Disease Health-Related Behaviors, Ontario, Canada, 2015-2022

Author

Adams, Janica A., Osasah, Victoria, Paphitis, Katherine, Danish, Affan, Mather, Richard G., Russell, Curtis A., Pritchard, Jennifer, and Nelder, Mark P.

Subjects
Medical research, Medicine, Experimental, Age -- Health aspects, Health behavior -- Demographic aspects, Lyme disease -- Physiological aspects, Health
Abstract

Lyme disease is the most reported vectorborne disease affecting humans in Canada, and incidence continues to increase (1). In eastern North America, the blacklegged tick (Ixodes scapularis) is the primary [...]

Published
2024
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2. The distribution of Babesia odocoilei in Ixodes species ticks in Canada: Implications for one health surveillance

Author

Guillot, Camille, Pelletier, Jérôme, Aenishaenslin, Cécile, Coatsworth, Heather, Dibernardo, Antonia, Koffi, Jules K., Kulkarni, Manisha A., Rocheleau, Jean-Philippe, Wilson, Christy, Russell, Curtis, Nelder, Mark P., Badcock, Jacqueline, Carr, Justin, Checkley, Sylvia, Clow, Katie M., Cooper, Stephanie, Cork, Susan, Dumas, Ariane, Dergousoff, Shaun, Faraone, Nicoletta, Fraser, Erin, Graham-Derham, Scott, Irace-Cima, Alejandra, Iwasawa, Stefan, Jenkins, Emily, Leighton, Patrick A., McKay, Roman, Morshed, Muhammad, Pelletier, Roxane, Ripoche, Marion, Rochon, Kateryn, Thivierge, Karine, Voordouw, Maarten J., Ogden, Nicholas H., and Bouchard, Catherine

Published
2024
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6. Pathogen prospecting of museums: Reconstructing malaria epidemiology.

Author

Nelder, Mark P., Schats, Rachel, Poinar, Hendrik N., Cooke, Amanda, and Brickley, Megan B.

Subjects
*MALARIA, *PHYTOPATHOGENIC microorganisms, *MALARIA prevention, *INSECTICIDE resistance, *EPIDEMIOLOGY, *NATURAL history museums
Abstract

Malaria is a disease of global significance. Ongoing changes to the earth's climate, antimalarial resistance, insecticide resistance, and socioeconomic decline test the resilience of malaria prevention programs. Museum insect specimens present an untapped resource for studying vector-borne pathogens, spurring the question: Do historical mosquito collections contain Plasmodium DNA, and, if so, can museum specimens be used to reconstruct the historical epidemiology of malaria? In this Perspective, we explore molecular techniques practical to pathogen prospecting, which, more broadly, we define as the science of screening entomological museum specimens for human, animal, or plant pathogens. Historical DNA and pathogen prospecting provide a means of describing the coevolution of human, vector, and parasite, informing the development of insecticides, diagnostics, therapeutics, and vaccines. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Additional file 1 of Monitoring the patterns of submission and presence of tick-borne pathogens in Ixodes scapularis collected from humans and companion animals in Ontario, Canada (2011���2017)

Author

Nelder, Mark P., Russell, Curtis B., Dibernardo, Antonia, Clow, Katie M., Johnson, Steven, Cronin, Kirby, Patel, Samir N., and Lindsay, L. Robbin

Abstract

Additional file 1: Table S1. Blacklegged tick sample submission rates by host and public health unit: Ontario, Canada (2011���2017). Table S2. Maximum likelihood estimate (MLE) prevalence of pathogens in blacklegged ticks from humans and companion animals, by public health unit: Ontario, Canada (2011���2017). Table S3. Univariable negative binomial regression to explore the influence of blacklegged tick submissions from animals on submissions from humans: Ontario, Canada (2011���2017). Bolded lines indicate significant associations (P

Published
2021
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19. Intestinal toxemia botulism in 3 adults, Ontario, Canada, 2006-2008

Author

Sheppard, Yolanda D., Middleton, Dean, Whitfield, Yvonne, Tyndel, Felix, Haider, Shariq, Spiegelman, Jamie, Swartz, Richard H., Nelder, Mark P., Baker, Stacey L., Landry, Lisa, MacEachern, Ross, Deamond, Sherri, Ross, Lorrie, Peters, Garth, Baird, Michelle, Rose, David, Sanders, Greg, and Austin, John W.

Subjects
Crohn's disease -- Risk factors, Bacteremia -- Risk factors, Botulism -- Risk factors, Health
Abstract

Botulism is a neuroparalytic condition, typified by cranial nerve palsies that may be followed by descending symmetrical flaccid paralysis, which can lead to respiratory arrest and, in some instances, death [...]

Published
2012
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23. Surveillance for Lyme disease in Canada, 2009–2019.

Author

Gasmi, Salima, Koffi, Jules K., Nelder, Mark P., Russell, Curtis, Graham-Derham, Scott, Lachance, Lisa, Adhikari, Bijay, Badcock, Jacqueline, Baidoobonso, Shamara, Billard, Beverly A., Halfyard, Beth, Jodoin, Stéphanie, Singal, Mayank, and Bourgeois, Annie-Claude

Subjects
LYME disease, SYMPTOMS, AGE groups, PUBLIC health, NERVOUS system, OLDER patients
Abstract

Background: Lyme disease (LD) is a multisystem infection that can affect the skin, heart, joints and nervous system. In Canada, the incidence of LD cases has increased over the past decade making this a disease of public health concern. The objective of this study is to summarize the epidemiology of LD cases reported in Canada from 2009 through 2019. Methods: Incidence over time, case classification (confirmed and probable), seasonal and geographic distribution, demographic and clinical characteristics of reported LD cases were determined. Logistic regression was used to explore potential demographic risk factors for the occurrence of LD. Results: During 2009–2019, a total of 10,150 LD cases were reported by the provinces to the Public Health Agency of Canada, of which 7,242 (71.3%) were confirmed and 2,908 (28.7%) were probable cases. The annual count increased from 144 in 2009 to 2,634 in 2019, mainly due to an increase in locally acquired infections, from 65.3% to 93.6%, respectively. The majority of cases (92.1%) were reported from three provinces: Ontario (46.0%); Nova Scotia (28.0%); and Québec (18.1%). Most of the locally acquired cases (74.0%) were reported in the summer months of June (20.0%), July (35.4%) and August (18.6%). The highest incidence rates (cases per 100,000 population) were in children aged 5–9 years (45.0) and in adults aged 65–69 years (74.3), with 57.3% of all reported cases occurring among males. The most common presenting symptoms were single erythema migrans rash (75.1%) and arthritis (34.1%). The frequency of reported clinical manifestations varied among age groups and seasons with erythema migrans and arthritis at presentation reported more frequently in children than older patients. Conclusion: The results of this report highlight the continued emergence of LD in Canada and the need for further development and implementation of targeted awareness campaigns designed to minimize the burden of LD. [ABSTRACT FROM AUTHOR]

Published
2022
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27. Coxiella burnetii in wild-caught filth flies

Author

Nelder, Mark P., Lloyd, John E., Loftis, Amanda D., and Reeves, Will K.

Abstract

To the Editor: Coxiella burnetii, the agent of Q fever, is a bacterium and a potential agent of bioterrorism. The most frequent signs of infection in domestic animals are abortion [...]

Published
2008

30. Detection of municipalities at-risk of Lyme disease using passive surveillance of Ixodes scapularis as an early signal: A province-specific indicator in Canada

Author

Gasmi, Salima, primary, Ogden, Nicholas H., additional, Ripoche, Marion, additional, Leighton, Patrick A., additional, Lindsay, Robbin L., additional, Nelder, Mark P., additional, Rees, Erin, additional, Bouchard, Catherine, additional, Vrbova, Linda, additional, Rusk, Richard, additional, Russell, Curtis, additional, Pelcat, Yann, additional, Mechai, Samir, additional, Kotchi, Serge-Olivier, additional, and Koffi, Jules K., additional

Published
2019
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31. Estimating direct healthcare costs attributable to laboratory‐confirmed Lyme disease in Ontario, Canada: A population‐based matched cohort study using health administrative data

Author

Shing, Emily, primary, Wang, John, additional, Khoo, Edwin, additional, Evans, Gerald A., additional, Moore, Stephen, additional, Nelder, Mark P., additional, Patel, Samir N., additional, Russell, Curtis, additional, Sider, Doug, additional, and Sander, Beate, additional

Published
2019
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37. Occurrence and distribution of Ambylomma americanumas determined by passive surveillance in Ontario, Canada (1999–2016)

Author

Nelder, Mark P., Russell, Curtis B., Clow, Katie M., Johnson, Steven, Weese, J. Scott, Cronin, Kirby, Ralevski, Filip, Jardine, Claire M., and Patel, Samir N.

Abstract

The lone star tick, Amblyomma americanum, is spreading northward from its historical stronghold in the southeastern United States. As a vector and biting pest, public and veterinary health officials must remain vigilant of the lone star tick’s expanding range. We use ticks submitted to Public Health Ontario Laboratory (1999–2016) to describe the spatial and temporal dynamics of A. americanumin Ontario, Canada, as well as submitter demographics. We identified 847 A. americanumsubmissions during the surveillance period, with 773 (91.3%) non-travel-related and 74 (8.7%) travel-related submissions. Annual A. americanumsubmissions increased over the surveillance period. Approximately 91% of non-travel-related submissions were adult ticks and 9% were nymphs. The highest submission rates were from individuals living in the Eastern and South West regions of the province. Adult specimens were primarily submitted from May through July and nymphs from March through September. Higher numbers of submissions were from young children (<10 years) and older adults (55–74 years), with equal proportions of male and female submitters. The majority of travel-related submissions were from travellers returning from the southeastern United States (i.e., Florida, North Carolina, South Carolina, Tennessee, Texas). Amblyomma americanumdistribution is scattered in Ontario and submissions are likely the consequence of ongoing detection of adventive specimens. Further tick dragging is required to confirm the presence of established lone star tick populations in the province. Given the relatively rapid expansion of blacklegged ticks, Ixodes scapularis, populations in Ontario, we expect climate change to facilitate the range of expansion of A. americanuminto the province. We propose an algorithm for identifying A. americanum-risk areas, which will aid public and veterinary health officials when assessing the risks posed by lone star ticks.

Published
2019
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38. Population-Based Passive Tick Surveillance and Detection of Expanding Foci of Blacklegged Ticks Ixodes scapularis and the Lyme Disease Agent Borrelia burgdorferi in Ontario, Canada

Author

Nelder, Mark P., primary, Russell, Curtis, additional, Lindsay, L. Robbin, additional, Dhar, Badal, additional, Patel, Samir N., additional, Johnson, Steven, additional, Moore, Stephen, additional, Kristjanson, Erik, additional, Li, Ye, additional, and Ralevski, Filip, additional

Published
2014
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