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2. Precision study of B^* B\pi coupling for the static heavy-light meson

Author

Negishi, S., Matsufuru, H., and Onogi, T.

Subjects
High Energy Physics - Lattice
Abstract

We compute the B^*B\pi coupling \hat{g}_{\infty} for static heavy-light meson using all-to-all propagators. It is shown that low-mode averaging with 100 low-lying eigenmodes indeed improves the signal for the 2-point and 3-point functions for heavy-light meson significantly. Our study suggests that the all-to-all propagator will be a very efficient method for high precision computation of the B^*B\pi coupling especially in unquenched QCD where the number of configurations is limited., Comment: 30 pages, 25 figures, typos corrected

Published
2006
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14. Cover Image

Author

Sato, T., primary, Yamaguchi, M., additional, Murakami, Y., additional, Horigome, Y., additional, Negishi, S., additional, and Kasai, K., additional

Published
2018
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17. Precision study of B^* B��coupling for the static heavy-light meson

Author

Negishi, S., Matsufuru, H., and Onogi, T.

Subjects
High Energy Physics::Lattice, High Energy Physics::Phenomenology, High Energy Physics - Lattice (hep-lat), FOS: Physical sciences
Abstract

We compute the B^*B��coupling \hat{g}_{\infty} for static heavy-light meson using all-to-all propagators. It is shown that low-mode averaging with 100 low-lying eigenmodes indeed improves the signal for the 2-point and 3-point functions for heavy-light meson significantly. Our study suggests that the all-to-all propagator will be a very efficient method for high precision computation of the B^*B��coupling especially in unquenched QCD where the number of configurations is limited., 30 pages, 25 figures, typos corrected

Published
2006
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23. Soft X-ray photoemission spectroscopy of (LnO)CuS (Ln=Ce, Pr, Nd)

Author

Sato, H., primary, Nishimoto, S., additional, Takase, K., additional, Nakao, H., additional, Yoshikawa, K., additional, Higashi, M., additional, Taniguchi, M., additional, Negishi, H., additional, Negishi, S., additional, Takahashi, Y., additional, Takano, Y., additional, and Sekizawa, K., additional

Published
2006
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24. Direct evidence of band modification and suppression of superstructure inTiSe2upon Fe intercalation: An angle-resolved photoemission study

Author

Cui, X. Y., primary, Negishi, H., additional, Titova, S. G., additional, Shimada, K., additional, Ohnishi, A., additional, Higashiguchi, M., additional, Miura, Y., additional, Hino, S., additional, Jahir, A. M., additional, Titov, A., additional, Bidadi, H., additional, Negishi, S., additional, Namatame, H., additional, Taniguchi, M., additional, and Sasaki, M., additional

Published
2006
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40. Immunological dissimilarity in protein component (dynein 1) between outer and inner arms within sea urchin sperm axonemes

Author

Ogawa, K, Negishi, S, and Obika, M

Abstract

The 0.5 M KCl-treatment solubilizes the outer arms from sea urchin sperm axonemes. Approximately 30 percent of A-polypeptide, corresponding to dynein 1 in SDS- polyacrylamide gel, was solubilized by this treatment (as SEA-dynein 1). Electron microscopic observation indicated that the extracted axonemes lacked the outer arms in various degrees. The DEA-dynein 1 was that the extracted axonemes lacked the outer arms in various degrees. The SEA-dyenin 1 was purified and an antiserum against it was prepared in rabbits. The specificity of antiserum to dynein 1 was determined by immunoelectrophoresis and ouchterlony's double-diffusion test. The anti-dynein 1 serum inhibited ATPase activity of purified SEA-dynein 1 by 95 percent. By the indirect peroxidase-conjugated antibody method, the loci of SEA-dynein 1 within the intact, salt- extracted and mechanically disrupted axonemes were determined to be the outer arms: deposition of electron-dense materials which represents their localization was detected at the distal ends of the outer arms, in the case of intact axonemes. The 5-6 cross- bridge was hardly decorated. No decoration was seen in the salt-extracted axonemes lacking all the outer arms. In disrupted axonemes, which consist of single to several peripheral doublets, electron-dense materials were deposited only on the outer arms. Approximately 73 percent of axonemal ATPase activity sensitive to antiserum was solubilized by repeated salt-extractions. One-half of A-polypeptide (SEA-dynein 1 located at the outer arms) was contained in the pooled extracts. The extracted axonemes contained another half of A-polypeptide (SUA-dynein 1 supposed to locate at the inner arms) and retained 31 percent of axonemal ATPase activity that was almost resistant to antiserum. Solubilized SUA-dynein 1 was immunologically the same as SEA-dynein 1. This result indicates that in situ SUA-dynein 1 did not receive anti-dynein 1 antibodies, coinciding with the result obtained for salt-extracted axonemes lacking all the outer arms by the enzyme-antibody method mentioned above. These observations suggest that immunological dissimilarity in dynein 1 between outer and inner arms but do not tell us that the inner arms do not contain dynein 1.

Published
1982
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49. Efficacy of hard gummy candy chewing in improving masticatory function in Japanese children aged 6-12 years: A clinical trial.

Author

Sato K, Hayashi K, Oka K, Morishita S, Kurita K, Ishii K, and Negishi S

Subjects
Humans, Child, Female, Male, Japan, Candy, Bite Force, East Asian People, Mastication physiology
Abstract

Objectives: Japanese children have been shown to exhibit decreased masticatory function; however, limited evidence is available regarding the efficacy of certain food items in improving this issue. Therefore, this study examined the effects of chewing hard gummy candy on the masticatory function of Japanese children aged 6-12 years., Methods: The study included 26 participants (10 boys and 16 girls; mean age ± standard error = 9.3 ± 0.3 years) who were asked to chew hard gummy candy twice daily for 4 weeks at home. The lip-closing force, occlusal force, and masticatory performance of the participants were recorded before commencement (T1), 4 weeks after commencement (T2), and 4 weeks after completion (T3) of the training. Statistical analyses were performed using the Wilcoxon rank-sum test or the Wilcoxon signed-rank test with Bonferroni correction., Results: No significant differences in masticatory function by gender and age groups (defined based on mean age at T1) were observed at T1. The lip-closing and right occlusal forces increased significantly after 4 weeks of exercise, and the effects persisted for another 4 weeks after completion. The masticatory performance also improved after training, although these effects did not persist and deteriorated substantially 4 weeks after completion of the training., Conclusions: Habitual mastication training using hard gummy candy markedly enhances masticatory function (e.g., lip-closing force, occlusal force, and masticatory performance) in Japanese children., Competing Interests: Declaration of competing interest All authors are required to disclose any COI within the period of 12 months prior to the submission of any manuscript in the subject matter of which any company, entity, or organization has an interest.The corresponding author is required to complete this form with information from all the authors listed in the manuscript., (Copyright © 2024. Published by Elsevier B.V.)

Published
2024
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50. Risk factors for postgastric endoscopic submucosal dissection bleeding in direct oral anticoagulant users.

Author

Kagawa T, Ishikawa S, Hidaka Y, Colvin HS, Nakanishi A, Ohkawa J, Negishi S, Yasutomi E, Yamauchi K, Okamoto K, Sakakihara I, Izumikawa K, Yamamoto K, Takahashi S, Tanaka S, Matsuura M, Wato M, Hasui T, and Inaba T

Abstract

Objectives: Bleeding after endoscopic submucosal dissection (ESD) for gastric tumors in patients taking antithrombotic drugs, in particular direct oral anticoagulants (DOACs), remains unresolved; therefore, we evaluated the risk factors for post-ESD bleeding and drug differences in patients taking DOACs., Methods: We included 278 patients taking antithrombotic drugs who underwent gastric ESD between January 2017 and March 2022. Antithrombotic drugs were withdrawn following the 2017 guidelines (Appendix on anticoagulants including DOACs). To further clarify differences in antithrombotic agents' effects, the peri-cancerous mucosa in the resected specimen was pathologically evaluated according to the Updated Sydney System. Multivariate analysis was performed to assess the risk of post-ESD bleeding., Results: The incidence of post-ESD bleeding in patients taking DOACs was 19.6% (10/51). Among patients taking antithrombotic drugs, DOACs were identified as a possible factor involved in post-ESD bleeding (odds ratio [OR] 4.92). Among patients taking DOACs, possible factors included resection length diameter ≥30 mm (OR 3.72), presence of neutrophil infiltration (OR 2.71), lesions occurring in the lower third of stomach (OR 2.34), and preoperative antiplatelet use (OR 2.22). Post-ESD bleeding by DOAC type was 25.0% of patients (4/16) receiving apixaban, in 20.0% (3/15) receiving edoxaban, in 21.4% (3/14) receiving rivaroxaban, and in none of those receiving dabigatran., Conclusions: The administration of DOACs was shown to be a possible factor involved in post-ESD bleeding, and risk factors for patients taking DOACs included neutrophil infiltration. The pharmacological differences in the effects of DOACs contributing to bleeding in gastric ulcers suggest comparatively less bleeding with dabigatran after ESD., (© 2024 Japan Gastroenterological Endoscopy Society.)

Published
2024
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