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341 results on '"Neeman M"'

1. OP02.07: Boosting maternal and neonatal anti‐SARS‐CoV‐2 humoral immunity using a third mRNA vaccine dose

Author

Cahen‐Peretz, A., primary, Tsaitlin‐Mor, L., additional, Kam, H. Allouche, additional, Fraenkel, R., additional, Kabessa, M., additional, Cohen, S.M., additional, Lipschuetz, M., additional, Oiknine‐Djian, E., additional, Lianski, S., additional, Goldman‐Wohl, D., additional, Walfisch, A., additional, Kovo, M., additional, Neeman, M., additional, Wolf, D., additional, Yagel, S., additional, and Beharier, O., additional

Published
2022
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9. FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation

Author

Joshua I. Warrick, Wenhuo Hu, Hironobu Yamashita, Vonn Walter, Lauren Shuman, Jenna M. Craig, Lan L. Gellert, Mauro A. A. Castro, A. Gordon Robertson, Fengshen Kuo, Irina Ostrovnaya, Judy Sarungbam, Ying-bei Chen, Anuradha Gopalan, Sahussapont J. Sirintrapun, Samson W. Fine, Satish K. Tickoo, Kwanghee Kim, Jasmine Thomas, Nagar Karan, Sizhi Paul Gao, Timothy N. Clinton, Andrew T. Lenis, Timothy A. Chan, Zhiyu Chen, Manisha Rao, Travis J. Hollman, Yanyun Li, Nicholas D. Socci, Shweta Chavan, Agnes Viale, Neeman Mohibullah, Bernard H. Bochner, Eugene J. Pietzak, Min Yuen Teo, Gopa Iyer, Jonathan E. Rosenberg, Dean F. Bajorin, Matthew Kaag, Suzanne B. Merrill, Monika Joshi, Rosalyn Adam, John A. Taylor, Peter E. Clark, Jay D. Raman, Victor E. Reuter, Yu Chen, Samuel A. Funt, David B. Solit, David J. DeGraff, and Hikmat A. Al-Ahmadie

Subjects
Science
Abstract

Bladder cancer can often exhibit genomic and morphological heterogeneity. Here, the authors use genomics analysis to show lineage plasticity of bladder cancers with squamous differentiation, and identify key transcription factors related to this morphological and immune heterogeneity.

Published
2022
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10. Complexities of Smoking Education

Author

Neeman, R. L. and Neeman, M.

Abstract

This article discusses problems involved in the design of effective health education programs addressed to smoking prevention. (PD)

Published
1975

21. Author Correction: FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation

Author

Joshua I. Warrick, Wenhuo Hu, Hironobu Yamashita, Vonn Walter, Lauren Shuman, Jenna M. Craig, Lan L. Gellert, Mauro A. A. Castro, A. Gordon Robertson, Fengshen Kuo, Irina Ostrovnaya, Judy Sarungbam, Ying-bei Chen, Anuradha Gopalan, Sahussapont J. Sirintrapun, Samson W. Fine, Satish K. Tickoo, Kwanghee Kim, Jasmine Thomas, Nagar Karan, Sizhi Paul Gao, Timothy N. Clinton, Andrew T. Lenis, Timothy A. Chan, Ziyu Chen, Manisha Rao, Travis J. Hollman, Yanyun Li, Nicholas D. Socci, Shweta Chavan, Agnes Viale, Neeman Mohibullah, Bernard H. Bochner, Eugene J. Pietzak, Min Yuen Teo, Gopa Iyer, Jonathan E. Rosenberg, Dean F. Bajorin, Matthew Kaag, Suzanne B. Merrill, Monika Joshi, Rosalyn Adam, John A. Taylor, Peter E. Clark, Jay D. Raman, Victor E. Reuter, Yu Chen, Samuel A. Funt, David B. Solit, David J. DeGraff, and Hikmat A. Al-Ahmadie

Subjects
Science
Published
2022
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22. Feasibility of concurrent dual contrast enhancement using CEST contrast agents and superparamagnetic iron oxide particles.

Author

Gilad, A.A., Laarhoven, H.W.M. van, McMahon, M.T., Walczak, P., Heerschap, A., Neeman, M., Zijl, P.C. van, Bulte, J.W., Gilad, A.A., Laarhoven, H.W.M. van, McMahon, M.T., Walczak, P., Heerschap, A., Neeman, M., Zijl, P.C. van, and Bulte, J.W.

Abstract

Contains fulltext : 80681_aut.pdf (author's version ) (Open Access) Contains fulltext : 80681_pub.pdf (publisher's version ) (Closed access), A major challenge for cellular and molecular MRI is to study interactions between two different cell populations or biological processes. We studied the possibility to simultaneously image contrast agents based on two different MRI contrast mechanisms: chemical exchange saturation transfer (CEST) and enhancement of T2 relaxation. Various amounts of superparamagnetic iron oxide (SPIO) nanoparticles were mixed with a fixed concentration (250 microM) of the CEST agent poly-L-lysine. T2 maps, CEST maps, and frequency-dependent saturation spectra were then measured. Color-coded overlay maps demonstrated the feasibility of concurrent dual contrast enhancement. We found that at concentrations lower than 5 microg(Fe)/mL both contrast agents can be imaged simultaneously. At higher concentrations, the iron-based agent can be used to "shut off" the signal arising from the CEST agent. These initial findings are a first step toward using dual CEST/T2 contrast imaging for studying multiple cellular or molecular targets simultaneously in vivo.

Published
2009

23. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Author

Carmeliet, P, Dor, Y, Herbert, JM, Fukumura, D, Brusselmans, K, Dewerchin, M, Neeman, M, Bono, F, Abramovitch, R, Maxwell, P, Koch, CJ, Ratcliffe, P, Moons, L, Jain, RK, Collen, D, Keshert, E, and Keshet, E

Subjects
Vascular Endothelial Growth Factor A, medicine.medical_specialty, Angiogenesis, Mice, Nude, Apoptosis, CHO Cells, Endothelial Growth Factors, Biology, Cell Line, chemistry.chemical_compound, Mice, Internal medicine, Cricetinae, Oxygen homeostasis, medicine, Animals, Lymphokines, Multidisciplinary, Neovascularization, Pathologic, Cell growth, Vascular Endothelial Growth Factors, Stem Cells, Nuclear Proteins, Neoplasms, Experimental, Hypoxia (medical), Hypoxia-Inducible Factor 1, alpha Subunit, Cell Hypoxia, Cell biology, Vascular endothelial growth factor, DNA-Binding Proteins, Oxygen, Vascular endothelial growth factor A, Endocrinology, Glucose, Hypoxia-inducible factors, chemistry, Regional Blood Flow, Gene Targeting, Hypoxia-Inducible Factor 1, medicine.symptom, Stem cell, Cell Division, Transcription Factors
Abstract

As a result of deprivation of oxygen (hypoxia) and nutrients, the growth and viability of cells is reduced. Hypoxia-inducible factor (HIF)-1alpha helps to restore oxygen homeostasis by inducing glycolysis, erythropoiesis and angiogenesis. Here we show that hypoxia and hypoglycaemia reduce proliferation and increase apoptosis in wild-type (HIF-1alpha+/+) embryonic stem (ES) cells, but not in ES cells with inactivated HIF-1alpha genes (HIF-1alpha-/-); however, a deficiency of HIF-1alpha does not affect apoptosis induced by cytokines. We find that hypoxia/hypoglycaemia-regulated genes involved in controlling the cell cycle are either HIF-1alpha-dependent (those encoding the proteins p53, p21, Bcl-2) or HIF-1alpha-independent (p27, GADD153), suggesting that there are at least two different adaptive responses to being deprived of oxygen and nutrients. Loss of HIF-1alpha reduces hypoxia-induced expression of vascular endothelial growth factor, prevents formation of large vessels in ES-derived tumours, and impairs vascular function, resulting in hypoxic microenvironments within the tumour mass. However, growth of HIF-1alpha tumours was not retarded but was accelerated, owing to decreased hypoxia-induced apoptosis and increased stress-induced proliferation. As hypoxic stress contributes to many (patho)biological disorders, this new role for HIF-1alpha in hypoxic control of cell growth and death may be of general pathophysiological importance.

Published
1998

29. Applications of magnetic resonance in model systems: tumor biology and physiology

Author

Gillies, R.J., Bhuwalla, Z.M., Evelhoch, J.L., Garwood, M., Neeman, M., Robinson, S.P., Sotak, J., Sanden, B.P.J. van den, Gillies, R.J., Bhuwalla, Z.M., Evelhoch, J.L., Garwood, M., Neeman, M., Robinson, S.P., Sotak, J., and Sanden, B.P.J. van den

Abstract

Contains fulltext : 186997.pdf (publisher's version ) (Open Access)

Published
2000

48. Notes.

Author

Gibson, M. S., Beckett, A. H., Jolliffe, G. O., Neeman, M., Bunton, C. A., Spatcher, D. N., Atkinson, C. M., Brown, C. W., Simpson, J. C. E., Lewis, K. G., Carasso, J. I., and Pittman, R. W.

Published
1956
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