1. Glucose-6-phosphate dehydrogenase deficiency in northern Vietnam
- Author
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A Kongs, P Verlé, Marc Coosemans, Tt Tinh, Dh Nhan, Nd Thuong, Patrick Van der Stuyft, and Tt Uyen
- Subjects
Male ,Veterinary medicine ,Adolescent ,Endemic Diseases ,Ethnic group ,Plasmodium ,chemistry.chemical_compound ,G6PD deficiency ,parasitic diseases ,Prevalence ,medicine ,Humans ,Transmission ,Glucose-6-phosphate dehydrogenase ,Foothills ,Malaria, Falciparum ,Asia, Southeast ,Child ,geography ,geography.geographical_feature_category ,biology ,Public Health, Environmental and Occupational Health ,Plasmodium falciparum ,Protozoal diseases ,medicine.disease ,biology.organism_classification ,Malaria ,Glucosephosphate Dehydrogenase Deficiency ,Infectious Diseases ,Vietnam ,chemistry ,Child, Preschool ,Immunology ,Trait ,Parasitology ,Glucose-6-phosphate dehydrogenase deficiency - Abstract
The definitive version is available at www3.interscience.wiley.com, Summary Glucose-6-phosphate dehydrogenase (G6PD) deficiency was evaluated in 1676 schoolboys in northern Vietnam. The trait was nearly absent in boys of the Kinh (0.5%) and the Mong (0.7%) ethnic groups that traditionally have lived outside malaria transmission areas. Prevalences among ethnic groups living in the foothills, the breeding area of the main malaria vector Anopheles minimus, ranged from 9.7% to 31%. These findings support the hypothesis of a selective advantage of the trait in Plasmodium falciparum-endemic areas.
- Published
- 2000