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5. Bone Sarcomas

Author

Bajpai, Jyoti, Nayak, Prakash, Puri, Ajay, Badwe, Rajendra A., editor, Gupta, Sudeep, editor, Shrikhande, Shailesh V., editor, and Laskar, Siddhartha, editor

Published
2024
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19. Primary Alveolar Soft Part Sarcoma of Bone: A Rare Occurrence in 8 Patients, Posing a Diagnostic Challenge

Author

Kaur, Ramandeep, Ramadwar, Mukta, Gulia, Ashish, Pruthi, Manish, Rekhi, Bharat, Panjwani, Poonam K., Puri, Ajay, Nayak, Prakash, Bajpai, Jyoti, and Janu, Amit

Subjects
Sarcoma -- Diagnosis -- Care and treatment, Immunohistochemistry -- Analysis, Cancer -- Adjuvant treatment, Metastasis -- Risk factors -- Prevention, Health
Abstract

* Context.--Alveolar soft part sarcoma is a rare soft tissue tumor involving mainly deep soft tissue of the lower extremities. Primary bone involvement is extremely rare. Objective.--To discuss histopathologic and immunohistochemical features of alveolar soft part sarcoma along with challenges in diagnosis and management in the context of primary bone origin. Design.--Our study constituted 8 patients. Data were collected from the Tata Memorial Hospital, Mumbai, India, during a 10-year period. Results.--Five patients in our study were female and 3 were male. Their ages ranged from 13 to 56 years. Primary bone involvement was seen in the humerus, tibia, fibula, radius, calcaneus, and rib. Radiologic impression was that of a primary malignant bone tumor in all patients. Conventional histopathologic features were seen in 7 of 8 patients. Positive immunohistochemical expression for TFE3 was demonstrated in 6 patients. All patients had distant metastasis either at presentation or later in the course of the disease. Surgical excision of the primary tumor and adjuvant chemotherapy formed the basis of treatment. Four patients succumbed to disease and 2 were alive with disease. Conclusions.--Rare occurrences of primary bone alveolar soft part sarcoma posed a diagnostic challenge in the form of differential diagnoses of metastatic tumors resembling it either morphologically or immunohistochemically. The combined application of clinical and radiologic features along with characteristic histomorphology and immunohistochemistry helps to arrive at a definite diagnosis of alveolar soft part sarcoma. Aggressive behavior of this tumor and its refractoriness to conventional chemotherapy were evident from our series., Alveolar soft part sarcoma (ASPS) is a rare malignant soft tissue tumor of uncertain histogenesis. (1) It accounts for less than 1% of all soft tissue sarcomas. (1,2) It was [...]

Published
2022
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24. Design, Development and Performance Evaluation of Foot Operated Elephant Apple Core Cutter

Author

Saikia, Deepanka, Nayak, Prakash Kumar, Radhakrishnan, Kesavan, Barbhuiya, Javed Akhtar, Mandal, Sandip, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Chakrabarti, Debkumar, editor, Karmakar, Sougata, editor, and Salve, Urmi R., editor

Published
2022
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28. Radiation Therapy Dose Escalation in Unresectable Ewing Sarcoma: Final Results of a Phase 3 Randomized Controlled Trial

Author

Laskar, Siddhartha, Sinha, Shwetabh, Chatterjee, Abhishek, Khanna, Nehal, Manjali, Jifmi Jose, Puri, Ajay, Gulia, Ashish, Nayak, Prakash, Vora, Tushar, Chinnaswamy, Girish, Prasad, Maya, Bajpai, Jyoti, Juvekar, Shashikant, Desai, Subhash, Janu, Amit, Rangarajan, Venkatesh, Purandare, Nilendu, Shah, Sneha, Rekhi, Bharat, Jambhekar, Nirmala, Muckaden, Mary Ann, and Kurkure, Purna

Published
2022
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29. Outcomes of COVID-19 and risk factors in patients with cancer

Author

Sengar, Manju, Chinnaswamy, Girish, Ranganathan, Priya, Ashok, Apurva, Bhosale, Shilpushp, Biswas, Sanjay, Chaturvedi, Pankaj, Dhamne, Chetan, Divatia, Jigeeshu, D’Sa, Karishma, Jain, Hasmukh, Laskar, Sarbani, Moulik, Nirmalya Roy, Mummudi, Naveen, Nair, Sindhu, Nayak, Lingaraj, Nayak, Prakash, Patkar, Shraddha, Pawaskar, Preeti, Ramaswamy, Anant, Shetty, Omshree, Singh, Arjun, Sridhar, Epari, Thorat, Jayashree, Badwe, Rajendra, and Pramesh, C. S.

Published
2022
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40. Integrated approach of ultrasound with mild heat treatment on the quality characteristics of yacon (Smallanthus sonchifolius) tuber juice.

Author

Das, Puja, Nayak, Prakash Kumar, and Kesavan, Radha krishnan

Subjects
ARTIFICIAL neural networks, YACON, VITAMIN C, TUBERS, GENETIC algorithms, FOOD pasteurization
Abstract

The research delved into the ascendancy of thermosonication (TS) on elevating the alimentary components of yacon (Smallanthus sonchifolius) tuber juice, derived from the yacon plant. This investigation introduces an innovative approach utilizing artificial neural networks (ANNs) coupled with genetic algorithm (GA) for the multifaceted optimization of extraction procedures. It aims to pinpoint the most effective processing parameters for TS, including variations in amplitudes: X1 (40, 50, and 60%) and temperatures: X2 (30, 40, and 50°C) over sonication times: X3 (15, 30, 45, and 60 min). Further, the approach is focused to amplify quality of yacon juice (YJ) and microbial attributes by enhancing certain quality characteristics such as anti‐oxidant activity (AOA), ascorbic acid (AA), total phenolic content (TPC), total carotenoid content (TCC), total flavonoid content (TFC), yeast and mold count (YMC) and total viable count (TVC). The maximum levels of AOA (33.73 ± 2.21%), AA (25.82 ± 2.03 mg/100 ml), TPC (85.08 ± 3.67 mg GAE/ml), TCC (115.82 ± 2.46 βCE μg/ml), TFC (22.52 ± 2.11 mg QE/ml), TVC, and YMC (not detected) were achieved in thermosonicated YJs under optimal conditions using ANN coupled with GA. Practical Applications: Yacon tuber juice (YJ) treated with thermosonication (TS) showed improved nutritional characteristics, making them a valuable source of functional compounds for nutraceuticals and food industries. Research emphasizes the effectiveness of artificial neural network in predicting the extraction efficiency of YJ and proposes TS as a potential replacement for traditional thermal pasteurization to maintain or enhance YJ quality and functionality. TS provides cost‐effective and sustainable solutions to the food industry by reducing processing time and energy consumption when compared to pasteurization. [ABSTRACT FROM AUTHOR]

Published
2024
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43. Hybrid Live VM Migration: An Efficient Live VM Migration Approach in Cloud Computing

Author

Shakya, Abhishek ku., Garg, Deepak, Nayak, Prakash Ch., Barbosa, Simone Diniz Junqueira, Series Editor, Filipe, Joaquim, Series Editor, Kotenko, Igor, Series Editor, Sivalingam, Krishna M., Series Editor, Washio, Takashi, Series Editor, Yuan, Junsong, Series Editor, Zhou, Lizhu, Series Editor, Ghosh, Ashish, Series Editor, Luhach, Ashish Kumar, editor, Singh, Dharm, editor, Hsiung, Pao-Ann, editor, Hawari, Kamarul Bin Ghazali, editor, Lingras, Pawan, editor, and Singh, Pradeep Kumar, editor

Published
2019
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