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579 results on '"Navas-Carretero, Santiago"'

1. Adherence to a healthy lifestyle behavior composite score and cardiometabolic risk factors in Spanish children from the CORALS cohort

Author

Garcidueñas-Fimbres, Tany E., Gómez-Martínez, Carlos, Pascual-Compte, Maria, Jurado-Castro, Jose Manuel, Leis, Rosaura, Moreno, Luis A., Navas-Carretero, Santiago, Codoñer-Franch, Pilar, Echeverria, Ana Moreira, Pastor-Villaescusa, Belén, López-Rubio, Alicia, García, Sara Moroño, De Miguel-Etayo, Pilar, Martínez, J. Alfredo, Aguayo, Inmaculada Velasco, Vázquez-Cobela, Rocío, Escribano, Joaquín, Miguel-Berges, María Luisa, De La Torre-Aguilar, María José, Gil-Campos, Mercedes, Salas-Salvadó, Jordi, and Babio, Nancy

Published
2024
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3. Reproducibility and relative validity of a semi-quantitative food and beverage frequency questionnaire for Spanish children aged 3 to 11 years: the COME-Kids F&B-FQ

Author

Babio, Nancy, de Las Heras-Delgado, Sara, De Miguel-Etayo, Pilar, Pastor-Villaescusa, Belén, Leis, Rosaura, Garcidueñas-Fimbres, Tany E., Larruy-García, Alicia, Navas-Carretero, Santiago, Portoles, Olga, Flores-Rojas, Katherine, Vázquez-Cobela, Rocío, Shyam, Sangeetha, Miguel-Berges, María L., Martínez, J. Alfredo, Codoñer-Franch, Pilar, Gil-Campos, Mercedes, Moreno, Luis A., and Salas-Salvadó, Jordi

Published
2023
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4. Precision nutrition impact on metabolic health and quality of life in aging population after a 3-month intervention: A randomized intervention

Author

Galarregui, Cristina, Navas-Carretero, Santiago, Zulet, M. Angeles, González-Navarro, Carlos J., Martínez, J. Alfredo, de Cuevillas, Begoña, Marcos-Pasero, Helena, Aguilar-Aguilar, Elena, Reglero, Guillermo, Ramirez de Molina, Ana, Chausa, Paloma, Iniesta, Jose M., Hernando, M. Elena, Gómez, Enrique J., Garcia-Rudolph, Alejandro, García-Molina, Alberto, Loria-Kohen, Viviana, and Abete, Itziar

Published
2024
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5. Role of Eating Behavior and Stress in Maintenance of Dietary Changes During the PREVIEW Intervention

Author

Jalo, Elli, Fogelholm, Mikael, Westerterp-Plantenga, Margriet, Adam, Tanja C., Drummen, Mathijs, Huttunen-Lenz, Maija, Kjølbæk, Louise, Martinez, José Alfredo, Handjieva-Darlenska, Teodora, Taylor, Moira A., Brand-Miller, Jennie, Poppitt, Sally, Stratton, Gareth, Lam, Tony, Navas-Carretero, Santiago, Bogdanov, Georgi, Simpson, Liz, Muirhead, Roslyn, Silvestre, Marta P., Swindell, Nils, Raben, Anne, and Konttinen, Hanna

Published
2024
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6. Acute and two-week effects of neotame, stevia rebaudioside M and sucrose-sweetened biscuits on postprandial appetite and endocrine response in adults with overweight/obesity—a randomised crossover trial from the SWEET consortium

Author

Gibbons, Catherine, Beaulieu, Kristine, Almiron-Roig, Eva, Navas-Carretero, Santiago, Martínez, J. Alfredo, O’Hara, Beverley, O’Connor, Dominic, Nazare, Julie-Anne, Le Bail, Alain, Rannou, Cécile, Hardman, Charlotte, Wilton, Moon, Kjølbæk, Louise, Scott, Corey, Moshoyiannis, Hariklia, Raben, Anne, Harrold, Joanne A., Halford, Jason C.G., and Finlayson, Graham

Published
2024
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9. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEET beverages trial

Author

Almiron-Roig, Eva, Navas-Carretero, Santiago, Castelnuovo, Gabriele, Kjølbæk, Louise, Romo-Hualde, Ana, Normand, Mie, Maloney, Niamh, Hardman, Charlotte A., Hodgkins, Charo E., Moshoyiannis, Hariklia, Finlayson, Graham, Scott, Corey, Raats, Monique M., Harrold, Joanne A., Raben, Anne, Halford, Jason C.G., and Martínez, J. Alfredo

Published
2023
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10. Age- and sex-specific effects of a long-term lifestyle intervention on body weight and cardiometabolic health markers in adults with prediabetes: results from the diabetes prevention study PREVIEW

Author

Zhu, Ruixin, Craciun, Ionut, Bernhards-Werge, Jan, Jalo, Elli, Poppitt, Sally D., Silvestre, Marta P., Huttunen-Lenz, Maija, McNarry, Melitta A., Stratton, Gareth, Handjiev, Svetoslav, Handjieva-Darlenska, Teodora, Navas-Carretero, Santiago, Sundvall, Jouko, Adam, Tanja C., Drummen, Mathijs, Simpson, Elizabeth J., Macdonald, Ian A., Brand-Miller, Jennie, Muirhead, Roslyn, Lam, Tony, Vestentoft, Pia S., Færch, Kristine, Martinez, J. Alfredo, Fogelholm, Mikael, and Raben, Anne

Published
2022
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12. Perceived stress as a predictor of eating behavior during the 3-year PREVIEW lifestyle intervention

Author

Jalo, Elli, Konttinen, Hanna, Westerterp-Plantenga, Margriet, Adam, Tanja, Drummen, Mathijs, Huttunen-Lenz, Maija, Siig Vestentoft, Pia, Martinez, J. Alfredo, Handjiev, Svetoslav, Macdonald, Ian, Brand-Miller, Jennie, Poppitt, Sally, Swindell, Nils, Lam, Tony, Navas-Carretero, Santiago, Handjieva-Darlenska, Teodora, Taylor, Moira, Muirhead, Roslyn, Silvestre, Marta P., Raben, Anne, and Fogelholm, Mikael

Published
2022
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13. Associations of changes in reported and estimated protein and energy intake with changes in insulin resistance, glycated hemoglobin, and BMI during the PREVIEW lifestyle intervention study

Author

Drummen, Mathijs, Adam, Tanja C, Macdonald, Ian A, Jalo, Elli, Larssen, Thomas M, Martinez, J Alfredo, Handjiev-Darlenska, Teodora, Brand-Miller, Jennie, Poppitt, Sally D, Stratton, Gareth, Pietiläinen, Kirsi H, Taylor, Moira A, Navas-Carretero, Santiago, Handjiev, Svetoslav, Muirhead, Roslyn, Silvestre, Marta P, Swindell, Nils, Huttunen-Lenz, Maija, Schlicht, Wolfgang, Lam, Tony, Sundvall, Jouko, Raman, Laura, Feskens, Edith, Tremblay, Angelo, Raben, Anne, and Westerterp-Plantenga, Margriet S

Published
2021
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14. Precision nutrition impact on metabolic health and quality of life in aging population after a 3-month intervention: A randomized intervention

Author

European Commission, Ministerio de Economía, Industria y Competitividad (España), Diputación Foral de Navarra, Ministerio de Educación, Cultura y Deporte (España), AMC Natural Drinks, Congelados de Navarra, Europastry, Galletas Gullón, Hijo de José Martinez Somalo, Iberfruta, Reglero, Guillermo [0000-0002-7730-3486], Galarregui, Cristina, Navas-Carretero, Santiago, Zulet, M. Angeles, González-Navarro, Carlos J., Martínez, J Alfredo, de Cuevillas, Begoña, Marcos-Pasero, Helena, Aguilar-Aguilar, Elena, Reglero, Guillermo, Ramirez de Molina, Ana, Chausa, Paloma, Iniesta, Jose M., Hernando, M Elena, Gómez, Enrique J., Garcia-Rudolph, Alejandro, García-Molina, Alberto, Loria-Kohen, Viviana, Abete, Itziar, European Commission, Ministerio de Economía, Industria y Competitividad (España), Diputación Foral de Navarra, Ministerio de Educación, Cultura y Deporte (España), AMC Natural Drinks, Congelados de Navarra, Europastry, Galletas Gullón, Hijo de José Martinez Somalo, Iberfruta, Reglero, Guillermo [0000-0002-7730-3486], Galarregui, Cristina, Navas-Carretero, Santiago, Zulet, M. Angeles, González-Navarro, Carlos J., Martínez, J Alfredo, de Cuevillas, Begoña, Marcos-Pasero, Helena, Aguilar-Aguilar, Elena, Reglero, Guillermo, Ramirez de Molina, Ana, Chausa, Paloma, Iniesta, Jose M., Hernando, M Elena, Gómez, Enrique J., Garcia-Rudolph, Alejandro, García-Molina, Alberto, Loria-Kohen, Viviana, and Abete, Itziar

Abstract

Innovative precision dietary procedures are required to promote healthy aging. This study aimed to evaluate the effects of a personalised strategy based on the inclusion of individualised foods and digital tools on overall health status and quality of life within a follow-up of 3 months in older adults with overweight or obesity.

Published
2024

15. Acute and two-week effects of neotame, stevia rebaudioside M and sucrose-sweetened biscuits on postprandial appetite and endocrine response in adults with overweight/obesity:a randomised crossover trial from the SWEET consortium

Author

Gibbons, Catherine, Beaulieu, Kristine, Almiron-Roig, Eva, Navas-Carretero, Santiago, Martínez, J. Alfredo, O'Hara, Beverley, O'Connor, Dominic, Nazare, Julie Anne, Le Bail, Alain, Rannou, Cécile, Hardman, Charlotte, Wilton, Moon, Kjølbæk, Louise, Scott, Corey, Moshoyiannis, Hariklia, Raben, Anne, Harrold, Joanne A., Halford, Jason C.G., Finlayson, Graham, Gibbons, Catherine, Beaulieu, Kristine, Almiron-Roig, Eva, Navas-Carretero, Santiago, Martínez, J. Alfredo, O'Hara, Beverley, O'Connor, Dominic, Nazare, Julie Anne, Le Bail, Alain, Rannou, Cécile, Hardman, Charlotte, Wilton, Moon, Kjølbæk, Louise, Scott, Corey, Moshoyiannis, Hariklia, Raben, Anne, Harrold, Joanne A., Halford, Jason C.G., and Finlayson, Graham

Abstract

Background: Sweeteners and sweetness enhancers (S&SE) are used to replace energy yielding sugars and maintain sweet taste in a wide range of products, but controversy exists about their effects on appetite and endocrine responses in reduced or no added sugar solid foods. The aim of the current study was to evaluate the acute (1 day) and repeated (two-week daily) ingestive effects of 2 S&SE vs. sucrose formulations of biscuit with fruit filling on appetite and endocrine responses in adults with overweight and obesity. Methods: In a randomised crossover trial, 53 healthy adults (33 female, 20 male) with overweight/obesity in England and France consumed biscuits with fruit filling containing 1) sucrose, or reformulated with either 2) Stevia Rebaudioside M (StRebM) or 3) Neotame daily during three, two-week intervention periods with a two-week washout. The primary outcome was composite appetite score defined as [desire to eat + hunger + (100 − fullness) + prospective consumption]/4. Findings: Each formulation elicited a similar reduction in appetite sensations (3-h postprandial net iAUC). Postprandial insulin (2-h iAUC) was lower after Neotame (95% CI (0.093, 0.166); p < 0.001; d = −0.71) and StRebM (95% CI (0.133, 0.205); p < 0.001; d = −1.01) compared to sucrose, and glucose was lower after StRebM (95% CI (0.023, 0.171); p < 0.05; d = −0.39) but not after Neotame (95% CI (−0.007, 0.145); p = 0.074; d = −0.25) compared to sucrose. There were no differences between S&SE or sucrose formulations on ghrelin, glucagon-like peptide 1 or pancreatic polypeptide iAUCs. No clinically meaningful differences between acute vs. two-weeks of daily consumption were found. Interpretation: In conclusion, biscuits reformulated to replace sugar using StRebM or Neotame showed no differences in appetite or endocrine responses, acutely or after a two-week exposure, but can reduce postprandial insulin and glucose response in adults with overweight or obesity. Funding

Published
2024

16. Combining diaries and accelerometers to explain change in physical activity during a lifestyle intervention for adults with prediabetes:A PREVIEW sub-study

Author

Klos, Leon, Stratton, Gareth, Mackintosh, Kelly A., McNarry, Melitta A., Fogelholm, Mikael, Drummen, Mathijs, Macdonald, Ian, Martinez, J. Alfredo, Navas-Carretero, Santiago, Handjieva-Darlenska, Teodora, Bogdanov, Georgi, Gant, Nicholas, Poppitt, Sally D., Silvestre, Marta P., Brand-Miller, Jennie, Muirhead, Roslyn, Schlicht, Wolfgang, Huttunen-Lenz, Maija, Brodie, Shannon, Jalo, Elli, Westerterp-Plantenga, Margriet, Adam, Tanja, Vestentoft, Pia Siig, Tikkanen, Heikki, Quist, Jonas S., Raben, Anne, Swindell, Nils, Klos, Leon, Stratton, Gareth, Mackintosh, Kelly A., McNarry, Melitta A., Fogelholm, Mikael, Drummen, Mathijs, Macdonald, Ian, Martinez, J. Alfredo, Navas-Carretero, Santiago, Handjieva-Darlenska, Teodora, Bogdanov, Georgi, Gant, Nicholas, Poppitt, Sally D., Silvestre, Marta P., Brand-Miller, Jennie, Muirhead, Roslyn, Schlicht, Wolfgang, Huttunen-Lenz, Maija, Brodie, Shannon, Jalo, Elli, Westerterp-Plantenga, Margriet, Adam, Tanja, Vestentoft, Pia Siig, Tikkanen, Heikki, Quist, Jonas S., Raben, Anne, and Swindell, Nils

Abstract

Self-report and device-based measures of physical activity (PA) both have unique strengths and limitations; combining these measures should provide complementary and comprehensive insights to PA behaviours. Therefore, we aim to 1) identify PA clusters and clusters of change in PA based on self-reported daily activities and 2) assess differences in device-based PA between clusters in a lifestyle intervention, the PREVIEW diabetes prevention study. In total, 232 participants with overweight and prediabetes (147 women; 55.9 ± 9.5yrs; BMI ≥25 kg․m-2; impaired fasting glucose and/or impaired glucose tolerance) were clustered using a partitioning around medoids algorithm based on self-reported daily activities before a lifestyle intervention and their changes after 6 and 12 months. Device-assessed PA levels (PAL), sedentary time (SED), light PA (LPA), and moderate-to-vigorous PA (MVPA) were assessed using ActiSleep+ accelerometers and compared between clusters using (multivariate) analyses of covariance. At baseline, the self-reported “walking and housework” cluster had significantly higher PAL, MVPA and LPA, and less SED than the “inactive” cluster. LPA was higher only among the “cycling” cluster. There was no difference in the device-based measures between the “social-sports” and “inactive” clusters. Looking at the changes after 6 months, the “increased walking” cluster showed the greatest increase in PAL while the “increased cycling” cluster accumulated the highest amount of LPA. The “increased housework” and “increased supervised sports” reported least favourable changes in device-based PA. After 12 months, there was only minor change in activities between the “increased walking and cycling”, “no change” and “increased supervised sports” clusters, with no significant differences in device-based measures. Combining self-report and device-based measures provides better insights into the behaviours that change during an intervention. Walking and cycling may

Published
2024

17. Changes in urinary metabolomic profile show the effectiveness of a nutritional intervention in children 6–12 years old: The ALINFA study.

Author

Andueza, Naroa, Muñoz‐Prieto, David, Romo‐Hualde, Ana, Cuervo, Marta, and Navas‐Carretero, Santiago

Subjects
AMINO acid metabolism, FOOD consumption, SPANIARDS, LIPID metabolism, METABOLOMICS, FAT
Abstract

Diet plays an essential role in health and disease. Therefore, its determination is an important component of many investigations. The aim of the study was to evaluate the effect of a nutritional intervention on the urinary metabolome in children aged 6–12 years. Also, it was intended to identify biomarkers of diet quality and dietary intake. A 2‐month, randomized, controlled, parallel trial was conducted in Spanish children. The analyses focused on the ALINFA group, which followed a full‐fixed meal plan including healthy products, ready‐to‐eat meals, and healthy recipes. Diet quality was assessed by the KIDMED index and dietary intake by a food frequency questionnaire. Untargeted metabolomic analysis on urine samples was carried out, and multivariate analyses were performed for pattern recognition and characteristic metabolite identification. PLS‐DA and Volcano plot analyses were performed to identify the discriminating metabolites of this group. 12 putative metabolites were found to be the most relevant to this intervention. Most of them were products derived from protein and amino acid metabolism (N‐Ribosylhistidine, indolacrylic acid, and peptides) and lipid metabolism (3‐oxo‐2‐pentylcyclopentane‐1‐hexanoic acid methyl, Suberoyl‐L‐carnitine, and 7‐Dehydrodichapetalin E). All these metabolites decreased after the intervention, which was mainly associated with a decrease in the consumption of fatty meat and total fat, especially saturated fat. In turn, N‐Ribosylhistidine and Suberoyl‐L‐carnitine were negatively associated with diet quality, as well as able to predict the change in KIDMED index. In conclusion, the changes observed in urinary metabolome demonstrate the effectiveness of the ALINFA nutritional intervention. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Hybrid Evaluation of a Lifestyle Change Program to Prevent the Development of Type 2 Diabetes Among Individuals With Prediabetes: Intended and Observed Changes in Intervening Mechanisms.

Author

Huttunen-Lenz, Maija, Hansen, Sylvia, Raben, Anne, Westerterp-Plantenga, Margriet, Adam, Tanja, Macdonald, Ian, Stratton, Gareth, Swindell, Nils, Martinez, J. Alfredo, Navas-Carretero, Santiago, Handjieva-Darlenska, Teodora, Handjiev, Svetoslav, Poppitt, Sally D., Silvestre, Marta P., Larsen, Thomas Meinert, Vestentoft, Pia Siig, Fogelholm, Mikael, Jalo, Elli, Brand-Miller, Jennie, and Muirhead, Roslyn

Subjects
PREDIABETIC state, BEHAVIOR modification, RESEARCH funding, SELF-efficacy, HEALTH status indicators, STATISTICAL sampling, QUESTIONNAIRES, MULTIPLE regression analysis, BEHAVIOR, RANDOMIZED controlled trials, DESCRIPTIVE statistics, MULTIVARIATE analysis, PSYCHOLOGICAL adaptation, SURVEYS, HEALTH behavior, TYPE 2 diabetes, ONE-way analysis of variance, ANALYSIS of variance, RESEARCH methodology, FOOD habits, GROUP process, PHYSICAL activity
Abstract

Background: Lifestyle interventions can prevent type 2 diabetes (T2D) by successfully inducing behavioral changes (eg, avoiding physical inactivity and sedentariness, increasing physical activity and/or healthy eating) that reduce body weight and normalize metabolic levels (eg, HbA1c). For interventions to be successful, it is important to influence "behavioral mechanisms" such as self-efficacy, which motivate behavioral changes. Theory-based expectations of how self-efficacy, chronic stress, and mood changed over time were investigated through a group-based behavior change intervention (PREMIT). At 8 intervention sites, PREMIT was offered by trained primary care providers in 18 group-sessions over a period of 36 months, divided into 4 intervention phases. Adherence to the intervention protocol was assessed. Method: Participants (n = 962) with overweight and prediabetes who had achieved ≥8% weight loss during a diet reduction period and completed the intervention were categorized into 3 groups: infrequent, frequent, or very frequent group sessions attendance. The interactions between participation in the group sessions and changes in self-efficacy, stress, and mood were multivariate tested. Intervention sites were regularly asked where and how they deviated from the intervention protocol. Results: There was no increase in the participants' self-efficacy in any group. However, the level of self-efficacy was maintained among those who attended the group sessions frequently, while it decreased in the other groups. For all participants, chronic stress and the frequency of attending group sessions were inversely related. Significant differences in mood were found for all groups. All intervention centers reported specific activities, additional to intervention protocol, to promote participation in the group sessions. Conclusions: The results suggest that the behavioral changes sought by trained primary care providers are related to attendance frequency and follow complex trajectories. The findings also suggest that group-based interventions in naturalistic primary care settings aimed at preventing T2D require formats and strategies that encourage participants to attend group sessions regularly. [ABSTRACT FROM AUTHOR]

Published
2024
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21. A Higher Adherence to the ALINFA Nutritional Intervention Is Effective for Improving Dietary Patterns in Children.

Author

Vázquez-Bolea, Natalia, Andueza, Naroa, Cuervo, Marta, and Navas-Carretero, Santiago

Subjects
LIFESTYLES, FOOD quality, HDL cholesterol, REPEATED measures design, STATISTICAL correlation, FRUIT, DIETARY patterns, NATURAL foods, RESEARCH funding, FOOD consumption, BODY mass index, LEPTIN, ADIPOSE tissues, MEDITERRANEAN diet, T-test (Statistics), DATA analysis, BODY composition, EDUCATIONAL outcomes, STATISTICAL sampling, QUESTIONNAIRES, ENZYME-linked immunosorbent assay, CHILD nutrition, BIOCHEMISTRY, RANDOMIZED controlled trials, GRAIN, LDL cholesterol, NUTRITIONAL requirements, DESCRIPTIVE statistics, MANN Whitney U Test, CHI-squared test, LONGITUDINAL method, WAIST circumference, HEALTH behavior, FOOD habits, NUTRITIONAL status, LEAN body mass, DIASTOLIC blood pressure, SPHYGMOMANOMETERS, CHOLESTEROL, STATISTICS, ANALYSIS of variance, VEGETABLES, HEALTH promotion, ANTHROPOMETRY, COMPARATIVE studies, NUTS, MEALS, SYSTOLIC blood pressure, CALORIMETRY, DATA analysis software, NUTRITION education, C-reactive protein, FASTING, TUMOR necrosis factors, REGRESSION analysis, BREAKFASTS, CHILDREN
Abstract

Food patterns are deteriorating and, consequently, not meeting nutritional recommendations. Learning about the adherence to a diet is crucial for understanding children's dietary habits. The objective of the present analysis was to assess the degree of compliance with the ALINFA nutritional intervention and the effectiveness of adherence groups, and to evaluate potential baseline factors predicting a higher adherence to the intervention. A total of 44 children aged 6 to 12 years-old participated in the eight-week intervention. A two-week dietary plan was specifically designed, providing participants with food products, ready-to-eat dishes, and recipes. An intake of 75% of calories of the prescribed diet was defined to divide the participants into high- and low-adherence groups (HA/LA, respectively). From the 44 participants, 24 showed a LA to the intervention, whereas 20 of them were in the HA group. Diet quality improved in both groups (p < 0.001), mainly by increasing cereals and nuts, and reducing pastries. A decrease in BMI z-score was observed (LA: p < 0.001; HA: p = 0.021). Fat mass (p = 0.002), LDL-c (p = 0.036), and CRP (p = 0.023) reductions were only achieved in the HA group, whereas leptin decreased only in the LA group (p = 0.046). All participants ameliorated their dietary habits, but those with better diet quality at baseline experienced greater enhancements in their nutritional status. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Combining diaries and accelerometers to explain change in physical activity during a lifestyle intervention for adults with pre-diabetes: A PREVIEW sub-study.

Author

Klos, Leon, Stratton, Gareth, Mackintosh, Kelly A., McNarry, Melitta A., Fogelholm, Mikael, Drummen, Mathijs, Macdonald, Ian, Martinez, J. Alfredo, Navas-Carretero, Santiago, Handjieva-Darlenska, Teodora, Bogdanov, Georgi, Gant, Nicholas, Poppitt, Sally D., Silvestre, Marta P., Brand-Miller, Jennie, Muirhead, Roslyn, Schlicht, Wolfgang, Huttunen-Lenz, Maija, Brodie, Shannon, and Jalo, Elli

Subjects
PHYSICAL activity, PREDIABETIC state, ADULTS, ANALYSIS of covariance, ACCELEROMETERS, CYCLING, FASTING
Abstract

Self-report and device-based measures of physical activity (PA) both have unique strengths and limitations; combining these measures should provide complementary and comprehensive insights to PA behaviours. Therefore, we aim to 1) identify PA clusters and clusters of change in PA based on self-reported daily activities and 2) assess differences in device-based PA between clusters in a lifestyle intervention, the PREVIEW diabetes prevention study. In total, 232 participants with overweight and prediabetes (147 women; 55.9 ± 9.5yrs; BMI ≥25 kg·m-2; impaired fasting glucose and/or impaired glucose tolerance) were clustered using a partitioning around medoids algorithm based on self-reported daily activities before a lifestyle intervention and their changes after 6 and 12 months. Device-assessed PA levels (PAL), sedentary time (SED), light PA (LPA), and moderate-to-vigorous PA (MVPA) were assessed using ActiSleep+ accelerometers and compared between clusters using (multivariate) analyses of covariance. At baseline, the self-reported "walking and housework" cluster had significantly higher PAL, MVPA and LPA, and less SED than the "inactive" cluster. LPA was higher only among the "cycling" cluster. There was no difference in the device-based measures between the "social-sports" and "inactive" clusters. Looking at the changes after 6 months, the "increased walking" cluster showed the greatest increase in PAL while the "increased cycling" cluster accumulated the highest amount of LPA. The "increased housework" and "increased supervised sports" reported least favourable changes in device-based PA. After 12 months, there was only minor change in activities between the "increased walking and cycling", "no change" and "increased supervised sports" clusters, with no significant differences in device-based measures. Combining self-report and device-based measures provides better insights into the behaviours that change during an intervention. Walking and cycling may be suitable activities to increase PA in adults with prediabetes. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Contributors

Author

Abete, Itziar, primary, Agirre, Xabier, additional, Ahlgren, Jennie, additional, Alkorta-Aranburu, Gorka, additional, Aller, Rocío, additional, Andres-Lacueva, Cristina, additional, Antonio de Luis, Daniel, additional, Babino, Darwin, additional, Bar-El Dadon, Shimrit, additional, Bonet, Maria Luisa, additional, Bordoni, Laura, additional, Borel, Patrick, additional, Bosch, Annet M., additional, Brown, Steven, additional, Busso, Dolores, additional, Calabriso, Nadia, additional, Capurso, Antonio, additional, Capurso, Cristiano, additional, Cariello, Marica, additional, Carluccio, Maria Annunziata, additional, Casas-Agustench, Patricia, additional, Cheatham, Carol L., additional, Chirita-Emandi, Adela, additional, Chittoor, Geetha, additional, Choi, Myung-Sook, additional, Choi, Sang-Woon, additional, Cordero, Paul, additional, Corrales, Fernando J., additional, Cortés, Víctor, additional, Cross, Nicholas C.P., additional, Crujeiras, Ana B., additional, Curi, Rui, additional, De Caterina, Raffaele, additional, de Lorenzo, David, additional, Desmarchelier, Charles, additional, Dong, Olivia, additional, Estruch, Ramón, additional, Ezponda, Teresa, additional, Fenech, Michael, additional, Ferguson, Lynnette R., additional, Fischer, Karina, additional, Fontana, Luigi, additional, Friso, Simonetta, additional, Gabbianelli, Rosita, additional, Garaulet, Marat, additional, Garcia-Irigoyen, Oihane, additional, Gil, Angel, additional, Gómez-Abellán, Purificación, additional, Görman, Ulf, additional, Harris, William S., additional, Hernandez-Vazquez, Alain de J., additional, Hugenholtz, Paul, additional, Hyde, Lara K., additional, Ibáñez, Clara, additional, Izaola, Olatz, additional, Jones, Peter J.H., additional, Kirwan, Richard, additional, Kohlmeier, Martin, additional, Krupenko, Natalia I., additional, Kwon, Eun-Young, additional, Lamming, Dudley W., additional, Lamuela-Raventos, Rosa M., additional, Langin, Dominique, additional, Langley-Evans, Simon, additional, Lira do Amaral, Cátia, additional, Lopez-Minguez, Jesus, additional, Madonna, Rosalinda, additional, Mansego, Maria L., additional, Marotz, Clarisse, additional, Martinez, J. Alfredo, additional, Massaro, Marika, additional, McRitchie, Susan, additional, Mesmar, Bayan, additional, Milagro, Fermín I., additional, Moreno-Aliaga, María J., additional, Moreno-Indias, Isabel, additional, Moschetta, Antonio, additional, Navas-Carretero, Santiago, additional, Niculescu, Mihai, additional, Nordström, Karin, additional, Novo, Francisco J., additional, Oben, Jude A., additional, Odriozola, Leticia, additional, Ordovas, Jose M., additional, Palou, Andreu, additional, Parslow, Virginia R., additional, Pathmasiri, Wimal, additional, Pérez-Castrillón, José Luis, additional, Pérusse, Louis, additional, Piccinin, Elena, additional, Plaza-Diaz, Julio, additional, Prósper, Felipe, additional, Qi, Lu, additional, Ralston, Jessica C., additional, Ramírez de Molina, Ana, additional, Rasti, George, additional, Reifen, Ram, additional, Renda, Giulia, additional, Riancho, José A., additional, Riancho del Moral, José Antonio, additional, Rivadeneira, Fernando, additional, Roche, Helen M., additional, Ruiz-Mambrilla, Marta, additional, Ruiz-Ojeda, Francisco Javier, additional, Salas-Pérez, Francisca, additional, San-Cristobal, Rodrigo, additional, Santander, Nicolás, additional, Santos, José L., additional, Saupe, Jörg, additional, Scoditti, Egeria, additional, Serhan, Charles N., additional, Simonet, Nicolas G., additional, Simopoulos, Artemis P., additional, Steinle, Nanette, additional, Sumner, Susan C.J., additional, Tinahones, Francisco J., additional, Vaquero, Alejandro, additional, Vazquez-Vidal, Itzel, additional, Velazquez-Arellano, Antonio, additional, Viguerie, Nathalie, additional, Vinciguerra, Manlio, additional, Visioli, Francesco, additional, Vizmanos, José L., additional, von Lintig, Johannes, additional, Voruganti, Venkata Saroja, additional, Wanders, Ronald J.A., additional, Wang, Tiange, additional, Wiltshire, Tim, additional, Yu, Deyang, additional, Zarrinpar, Amir, additional, Zeisel, Steven H., additional, and Zulet, Maria Angeles, additional

Published
2020
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29. Associations of obesity phenotypes with weight change, cardiometabolic benefits, and type 2 diabetes incidence during a lifestyle intervention: results from the PREVIEW study

Author

Zhu, Ruixin, primary, Huttunen-Lenz, Maija, additional, Stratton, Gareth, additional, Handjieva-Darlenska, Teodora, additional, Handjiev, Svetoslav, additional, Sundvall, Jouko, additional, Silvestre, Marta P., additional, Jalo, Elli, additional, Pietiläinen, Kirsi H., additional, Adam, Tanja C., additional, Drummen, Mathijs, additional, Simpson, Elizabeth J., additional, Taylor, Moira A., additional, Poppitt, Sally D., additional, Navas-Carretero, Santiago, additional, Martinez, J. Alfredo, additional, Schlicht, Wolfgang, additional, Fogelholm, Mikael, additional, Brand-Miller, Jennie, additional, and Raben, Anne, additional

Published
2023
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30. Compositional analysis of the associations between 24-h movement behaviours and cardio-metabolic risk factors in overweight and obese adults with pre-diabetes from the PREVIEW study: cross-sectional baseline analysis

Author

Swindell, Nils, Rees, Paul, Fogelholm, Mikael, Drummen, Mathijs, MacDonald, Ian, Martinez, J. Alfredo, Navas-Carretero, Santiago, Handjieva-Darlenska, Teodora, Boyadjieva, Nadka, Bogdanov, Georgi, Poppitt, Sally D., Gant, Nicholas, Silvestre, Marta P., Brand-Miller, Jennie, Schlicht, Wolfgang, Muirhead, Roslyn, Brodie, Shannon, Tikkanen, Heikki, Jalo, Elli, Westerterp-Plantenga, Margriet, Adam, Tanja, Vestentoft, Pia Siig, Larsen, Thomas M., Raben, Anne, and Stratton, Gareth

Published
2020
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31. Associations of vitamin D status with dietary intakes and physical activity levels among adults from seven European countries: the Food4Me study

Author

Manios, Yannis, Moschonis, George, Lambrinou, Christina P., Mavrogianni, Christina, Tsirigoti, Lydia, Hoeller, Ulrich, Roos, Franz F., Bendik, Igor, Eggersdorfer, Manfred, Celis-Morales, Carlos, Livingstone, Katherine M., Marsaux, Cyril F. M., Macready, Anna L., Fallaize, Rosalind, O’Donovan, Clare B., Woolhead, Clara, Forster, Hannah, Walsh, Marianne C., Navas-Carretero, Santiago, San-Cristobal, Rodrigo, Kolossa, Silvia, Hallmann, Jacqueline, Jarosz, Mirosław, Surwiłło, Agnieszka, Traczyk, Iwona, Drevon, Christian A., van Ommen, Ben, Grimaldi, Keith, Matthews, John N. S., Daniel, Hannelore, Martinez, J. Alfredo, Lovegrove, Julie A., Gibney, Eileen R., Brennan, Lorraine, Saris, Wim H. M., Gibney, Mike, Mathers, John C., and on behalf of the Food4Me Study

Published
2018
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32. Correlates of overall and central obesity in adults from seven European countries: findings from the Food4Me Study

Author

Celis-Morales, Carlos, Livingstone, Katherine M., Affleck, Alexander, Navas-Carretero, Santiago, San-Cristobal, Rodrigo, Martinez, J Alfredo, Marsaux, Cyril F. M., Saris, Wim H. M., O’Donovan, Clare B, Forster, Hannah, Woolhead, Clara, Gibney, Eileen R., Walsh, Marianne C., Brennan, Lorraine, Gibney, Mike, Moschonis, George, Lambrinou, Christina-Paulina, Mavrogianni, Christina, Manios, Yannis, Macready, Anna L., Fallaize, Rosalind, Lovegrove, Julie A., Kolossa, Silvia, Daniel, Hannelore, Traczyk, Iwona, Drevon, Christian A, Mathers, John C., and on behalf of the Food4Me Study

Published
2018
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34. Associations of obesity phenotypes with weight change, cardiometabolic benefits, and type 2 diabetes incidence during a lifestyle intervention: results from the PREVIEW study

Author

Zhu, Ruixin, Huttunen-Lenz, Maija, Stratton, Gareth, Handjieva-Darlenska, Teodora, Handjiev, Svetoslav, Sundvall, Jouko, Silvestre, Marta P, Jalo, Elli, Pietiläinen, Kirsi H, Adam, Tanja C, Drummen, Mathijs, Simpson, Elizabeth J, Taylor, Moira A, Poppitt, Sally D., Navas-Carretero, Santiago, Martinez, J Alfredo, Schlicht, Wolfgang, Fogelholm, Mikael, Brand-Miller, Jennie, Raben, Anne, Zhu, Ruixin, Huttunen-Lenz, Maija, Stratton, Gareth, Handjieva-Darlenska, Teodora, Handjiev, Svetoslav, Sundvall, Jouko, Silvestre, Marta P, Jalo, Elli, Pietiläinen, Kirsi H, Adam, Tanja C, Drummen, Mathijs, Simpson, Elizabeth J, Taylor, Moira A, Poppitt, Sally D., Navas-Carretero, Santiago, Martinez, J Alfredo, Schlicht, Wolfgang, Fogelholm, Mikael, Brand-Miller, Jennie, and Raben, Anne

Abstract

Background/Objectives: Some individuals with overweight/obesity may be relatively metabolically healthy (MHO) and have a lower risk of cardiovascular disease than those with metabolically unhealthy overweight/obesity (MUO). We aimed to compare changes in body weight and cardiometabolic risk factors and type 2 diabetes incidence during a lifestyle intervention between individuals with MHO vs MUO. Methods: This post-hoc analysis included 1012 participants with MHO and 1153 participants with MUO at baseline in the randomized trial PREVIEW. Participants underwent an eight-week low-energy diet phase followed by a 148-week lifestyle-based weight-maintenance intervention. Adjusted linear mixed models and Cox proportional hazards regression models were used. Results: There were no statistically significant differences in weight loss (%) between participants with MHO vs MUO over 156 weeks. At the end of the study, weight loss was 2.7% (95% CI, 1.7%–3.6%) in participants with MHO and 3.0% (2.1%–4.0%) in those with MUO. After the low-energy diet phase, participants with MHO had smaller decreases in triglyceride (mean difference between MHO vs MUO 0.08 mmol·L−1 [95% CI, 0.04–0.12]; P < 0.001) but similar reductions in fasting glucose and HOMA-IR than those with MUO. However, at the end of weight maintenance, those with MHO had greater reductions in triglyceride (mean difference −0.08 mmol·L−1 [−0.12–−0.04]; P < 0.001), fasting glucose, 2-hour glucose (difference −0.28 mmol·L−1 [−0.41–−0.16]; P < 0.001), and HOMA-IR than those with MUO. Participants with MHO had smaller decreases in diastolic blood pressure and HbA1c and greater decreases in HDL cholesterol after weight loss than those with MUO, whereas the statistically significant differences disappeared at the end of weight maintenance. Participants with MHO had lower 3-year type 2 diabetes incidence than those with

Published
2023

36. Associations Between Eating Speed, Diet Quality, Adiposity, and Cardiometabolic Risk Factors

Author

Garcidueñas-Fimbres, Tany E., primary, Paz-Graniel, Indira, additional, Gómez-Martínez, Carlos, additional, Jurado-Castro, Jose Manuel, additional, Leis, Rosaura, additional, Escribano, Joaquin, additional, Moreno, Luis A., additional, Navas-Carretero, Santiago, additional, Portoles, Olga, additional, Pérez-Vega, Karla A., additional, Gil-Campos, Mercedes, additional, López-Rubio, Alicia, additional, Rey-Reñones, Cristina, additional, De Miguel-Etayo, Pilar, additional, Martínez, J. Alfredo, additional, Flores-Rojas, Katherine, additional, Vázquez-Cobela, Rocío, additional, Luque, Verónica, additional, Miguel-Berges, Maria Luisa, additional, Pastor-Villaescusa, Belén, additional, Llorente-Cantarero, Francisco Jesus, additional, Salas-Salvadó, Jordi, additional, Babio, Nancy, additional, Schröder, Helmut, additional, Moreira, Ana, additional, Fitó, Montse, additional, Baltodano, Mayela Solis, additional, Muñoz-Aguayo, Daniel, additional, Blanchart, Gemma, additional, Gaixas, Sònia, additional, Zomeño, María Dolores, additional, Lorenzo, Isaury, additional, Jurado-Castro, José Manuel, additional, Llorente-Cantarero, Francisco Jesús, additional, De La Torre-Aguilar, Maria José, additional, Aguayo, Inmaculada Velasco, additional, Alfredo-Martínez, J., additional, Cuevillas, Begoña, additional, Goñi, María, additional, Hernández, María, additional, Diez, Salomé Pérez, additional, Cristobo, Carmen, additional, Escribano, Joaquín, additional, Ferré, Natalia, additional, Martín, Francisco, additional, Rey, Cristina, additional, Mimbreros, Gisela, additional, Pedraza, Ana, additional, Salvadó, Olga, additional, Velasco, Marta Ruiz, additional, Bilbao Sustacha, José Ángel, additional, Pinilla, Yolanda Herranz, additional, Feliu, Albert, additional, Closas, Ricardo, additional, Rios, Lidia, additional, Compte, María Pascual, additional, Gheorghita, Irina, additional, Heras-Delgado, Sara de las, additional, Alcázar, Mireia, additional, Simón, Olga, additional, Torre, Sònia de la, additional, Tudela, Càrol, additional, Garcidueñas-Fimbres, Tany E., additional, Picáns-Leis, Rosaura, additional, Franch, Pilar Codoñer, additional, Corella, Dolores, additional, Carbonell, Vanessa Martín, additional, Sorlí, José V., additional, Moreno, Luís A., additional, Santaliestra-Pasias, Alba Ma, additional, Miguel-Berges, María Luisa, additional, Argente-Arizon, Pilar, additional, Gimenez-Legarre, Natalia, additional, Flores-Barrantes, Paloma, additional, Pérez-Gimeno, Gloria, additional, Seral-Cortés, Miguel, additional, Martinez, Andrea Jimeno, additional, and Maneschy, Ivie, additional

Published
2023
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39. Acute and repeated impact of sweeteners and sweetness enhancers in solid and semi-solid foods on appetite: protocol for a multicentre, cross-over, RCT in people with overweight/obesity – the SWEET Project

Author

Gibbons, Catherine, primary, O'Hara, Beverley, additional, O’Connor, Dominic, additional, Hardman, Charlotte, additional, Wilton, Moon, additional, Harrold, Joanne A, additional, Almiron-Roig, Eva, additional, Navas-Carretero, Santiago, additional, Hodgkins, Charo E, additional, Nazare, Julie Anne, additional, Alligier, Maud, additional, Martínez, Jose Alfredo, additional, Scott, Corey, additional, Kjølbæk, Louise, additional, Normand, Mie, additional, Rannou, Cécile, additional, Blaak, Ellen E, additional, Feskens, Edith, additional, Moshoyiannis, Hariklia, additional, Raben, Anne, additional, Halford, Jason C G, additional, Beaulieu, Kristine, additional, and Finlayson, Graham, additional

Published
2022
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40. Corrigendum: Reliability and validation of the child eating behavior questionnaire in 3- to 6-year-old Spanish children

Author

Jimeno-Martínez, Andrea, primary, Maneschy, Ivie, additional, Moreno, Luis A., additional, Bueno-Lozano, Gloria, additional, De Miguel-Etayo, Pilar, additional, Flores-Rojas, Katherine, additional, Jurado-Castro, Jose Manuel, additional, de Lamas, Carmela, additional, Vázquez-Cobela, Rocio, additional, Martinez-Lacruz, Raúl, additional, Portoles, Olga, additional, Martínez, J. Alfredo, additional, Navas-Carretero, Santiago, additional, Schröder, Helmut, additional, Fitó, Montserrat, additional, Babio, Nancy, additional, Salas-Salvadó, Jordi, additional, Leis, Rosaura, additional, Gil-Campos, Mercedes, additional, and Rupérez, Azahara I., additional

Published
2022
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41. Protocol for a multicentre, parallel, randomised, controlled trial on the effect of sweeteners and sweetness enhancers on health, obesity and safety in overweight adults and children: the SWEET project

Author

Kjølbæk, Louise, primary, Manios, Yannis, additional, Blaak, Ellen E, additional, Martínez, J. Alfredo, additional, Feskens, Edith J M, additional, Finlayson, Graham, additional, Andersen, Sabina S H, additional, Reppas, Kyriakos, additional, Navas-Carretero, Santiago, additional, Adam, Tanja C, additional, Hodgkins, Charo E, additional, del Álamo, Marta, additional, Lam, Tony, additional, Moshoyiannis, Hariklia, additional, Halford, Jason C G, additional, Harrold, Joanne A, additional, and Raben, Anne, additional

Published
2022
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43. results from the diabetes prevention study PREVIEW

Author

Zhu, Ruixin, Craciun, Ionut, Bernhards-Werge, Jan, Jalo, Elli, Poppitt, Sally D, Silvestre, Marta P, Huttunen-Lenz, Maija, McNarry, Melitta A, Stratton, Gareth, Handjiev, Svetoslav, Handjieva-Darlenska, Teodora, Navas-Carretero, Santiago, Sundvall, Jouko, Adam, Tanja C, Drummen, Mathijs, Simpson, Elizabeth J, Macdonald, Ian A, Brand-Miller, Jennie, Muirhead, Roslyn, Lam, Tony, Vestentoft, Pia S, Færch, Kristine, Martinez, J Alfredo, Fogelholm, Mikael, Raben, Anne, and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Subjects
Weight loss, SDG 3 - Good Health and Well-being, Men, Women, Young people, Obesity, Older people, Cardiovascular disease, Middle-aged people, Weight loss maintenance
Abstract

Funding: Open Access funding provided by University of Helsinki including Helsinki University Central Hospital. This research was supported by the EU Seventh Framework Programme (FP7; 2007– 2013) (grant no. 312057); National Health and Medical Research Council (EU Collaborative Grant AUS 8, ID 1067711); Glycemic Diabetologia Index Foundation Australia through royalties to the University of Sydney; Health Research Council of New Zealand (grant no. 14/191) and University of Auckland Faculty Research Development Fund; Cambridge Weight Plan, which donated all products for the 8 week weight loss period; Danish Agriculture & Food Council; Danish Meat Research Institute; National Institute for Health Research Biomedical Research Centre (NIHR BRC) (UK); Biotechnology and Biological Sciences Research Council (BBSRC) (UK); Engineering and Physical Sciences Research Council (EPSRC) (UK); Nutritics (Dublin), which donated all dietary analysis software used by the University of Nottingham; Juho Vainio Foundation (Finland); Academy of Finland (grant nos 272376, 314383, 266286 and 314135); Finnish Medical Foundation; Gyllenberg Foundation (Finland); Novo Nordisk Foundation; Finnish Diabetes Research Foundation; University of Helsinki; Government Research Funds for Helsinki University Hospital; Jenny and Antti Wihuri Foundation (Finland); Emil Aaltonen Foundation (Finland); and China Scholarship Council. The funders were not involved in the design of the study, the collection, analysis and interpretation of the data or writing of the report and did not impose any restrictions regarding the publication of the report. AIMS/HYPOTHESIS: Lifestyle interventions are the first-line treatment option for body weight and cardiometabolic health management. However, whether age groups or women and men respond differently to lifestyle interventions is under debate. We aimed to examine age- and sex-specific effects of a low-energy diet (LED) followed by a long-term lifestyle intervention on body weight, body composition and cardiometabolic health markers in adults with prediabetes (i.e. impaired fasting glucose and/or impaired glucose tolerance). METHODS: This observational study used longitudinal data from 2223 overweight participants with prediabetes in the multicentre diabetes prevention study PREVIEW. The participants underwent a LED-induced rapid weight loss (WL) period followed by a 3 year lifestyle-based weight maintenance (WM) intervention. Changes in outcomes of interest in prespecified age (younger: 25-45 years; middle-aged: 46-54 years; older: 55-70 years) or sex (women and men) groups were compared. RESULTS: In total, 783 younger, 319 middle-aged and 1121 older adults and 1503 women and 720 men were included in the analysis. In the available case and complete case analyses, multivariable-adjusted linear mixed models showed that younger and older adults had similar weight loss after the LED, whereas older adults had greater sustained weight loss after the WM intervention (adjusted difference for older vs younger adults -1.25% [95% CI -1.92, -0.58], p

Published
2022

44. Gene methylation parallelisms between peripheral blood cells and oral mucosa samples in relation to overweight

Author

San-Cristobal, Rodrigo, Navas-Carretero, Santiago, Milagro, Fermín I., Riezu-Boj, J. Ignacio, Guruceaga, Elizabeth, Celis-Morales, Carlos, Livingstone, Katherine M., Brennan, Lorraine, Lovegrove, Julie A., Daniel, Hannelore, Saris, Wim H., Traczyk, Iwonna, Manios, Yannis, Gibney, Eileen R., Gibney, Michael J., Mathers, John C., and Martinez, J. Alfredo

Published
2016
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45. Profile of European adults interested in internet-based personalised nutrition: the Food4Me study

Author

Livingstone, Katherine M., Celis-Morales, Carlos, Navas-Carretero, Santiago, San-Cristobal, Rodrigo, O’Donovan, Clare B., Forster, Hannah, Woolhead, Clara, Marsaux, Cyril F. M., Macready, Anna L., Fallaize, Rosalind, Kolossa, Silvia, Tsirigoti, Lydia, Lambrinou, Christina P., Moschonis, George, Godlewska, Magdalena, Surwiłło, Agnieszka, Drevon, Christian A., Manios, Yannis, Traczyk, Iwona, Gibney, Eileen R., Brennan, Lorraine, Walsh, Marianne C., Lovegrove, Julie A., Alfredo Martinez, J., Saris, Wim H., Daniel, Hannelore, Gibney, Mike, and Mathers, John C.

Published
2016
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47. Does the effect of a 3-year lifestyle intervention on body weight and cardiometabolic health differ by prediabetes metabolic phenotype? A post-hoc analysis of the PREVIEW study

Author

Zhu, Ruixin, primary, Jalo, Elli, primary, Silvestre, Marta P., primary, Poppitt, Sally D., primary, Handjieva-Darlenska, Teodora, primary, Handjiev, Svetoslav, primary, Huttunen-Lenz, Maija, primary, Mackintosh, Kelly, primary, Stratton, Gareth, primary, Navas-Carretero, Santiago, primary, Pietiläinen, Kirsi H., primary, Simpson, Elizabeth, primary, Macdonald, Ian A., primary, Muirhead, Roslyn, primary, Brand-Miller, Jennie, primary, Fogelholm, Mikael, primary, Færch, Kristine, primary, Martinez, J. Alfredo, primary, Westerterp-Plantenga, Margriet S., primary, Adam, Tanja C., primary, and Raben, Anne, primary

Published
2022
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48. Factors influencing European consumer uptake of personalised nutrition. Results of a qualitative analysis

Author

Stewart-Knox, Barbara, Kuznesof, Sharron, Robinson, Jenny, Rankin, Audrey, Orr, Karen, Duffy, Maresa, Poínhos, Rui, de Almeida, Maria Daniel Vaz, Macready, Anna, Gallagher, Caroline, Berezowska, Aleksandra, Fischer, Arnout R.H., Navas-Carretero, Santiago, Riemer, Martina, Traczyk, Iwona, Gjelstad, Ingrid M.F., Mavrogianni, Christina, and Frewer, Lynn J.

Published
2013
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50. Acute and repeated impact of sweeteners and sweetness enhancers in solid and semi-solid foods on appetite : protocol for a multicentre, cross-over, RCT in people with overweight/obesity - the SWEET Project

Author

Gibbons, Catherine, O'Hara, Beverley, O'Connor, Dominic, Hardman, Charlotte, Wilton, Moon, Harrold, Joanne A., Almiron-Roig, Eva, Navas-Carretero, Santiago, Hodgkins, Charo E., Nazare, Julie Anne, Alligier, Maud, Martínez, Jose Alfredo, Scott, Corey, Kjølbæk, Louise, Normand, Mie, Rannou, Cécile, Blaak, Ellen E., Feskens, Edith, Moshoyiannis, Hariklia, Raben, Anne, Halford, Jason C.G., Beaulieu, Kristine, Finlayson, Graham, Gibbons, Catherine, O'Hara, Beverley, O'Connor, Dominic, Hardman, Charlotte, Wilton, Moon, Harrold, Joanne A., Almiron-Roig, Eva, Navas-Carretero, Santiago, Hodgkins, Charo E., Nazare, Julie Anne, Alligier, Maud, Martínez, Jose Alfredo, Scott, Corey, Kjølbæk, Louise, Normand, Mie, Rannou, Cécile, Blaak, Ellen E., Feskens, Edith, Moshoyiannis, Hariklia, Raben, Anne, Halford, Jason C.G., Beaulieu, Kristine, and Finlayson, Graham

Abstract

INTRODUCTION: Intake of free sugars in European countries is high and attempts to reduce sugar intake have been mostly ineffective. Non-nutritive sweeteners and sweetness enhancers (S&SEs) can maintain sweet taste in the absence of energy, but little is known about the impact of acute and repeated consumption of S&SE in foods on appetite. This study aims to evaluate the effect of acute and repeated consumption of two individual S&SEs and two S&SE blends in semisolid and solid foods on appetite and related behavioural, metabolic and health outcomes. METHODS AND ANALYSIS: A work package of the SWEET Project; this study consists of five double-blind randomised cross-over trials which will be carried out at five sites across four European countries, aiming to have n=213. Five food matrices will be tested across three formulations (sucrose-sweetened control vs two reformulated products with S&SE blends and no added sugar). Participants (body mass index 25-35 kg/m2; aged 18-60 years) will consume each formulation for 14 days. The primary endpoint is composite appetite score (hunger, inverse of fullness, desire to eat and prospective food consumption) over a 3-hour postprandial incremental area under the curve during clinical investigation days on days 1 and 14. ETHICS AND DISSEMINATION: The trial has been approved by national ethical committees and will be conducted in accordance with the Declaration of Helsinki. Results will be published in international peer-reviewed open-access scientific journals. Research data from the trial will be deposited in an open-access online research data archive. TRIAL REGISTRATION NUMBER: NCT04633681.

Published
2022

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