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2,991 results on '"Navarro Pablo"'

1. Cancer incidence estimation from mortality data: a validation study within a population-based cancer registry

Author

Redondo-Sánchez, Daniel, Rodríguez-Barranco, Miguel, Ameijide, Alberto, Alonso, Francisco J., Fernández-Navarro, Pablo, Jiménez-Moleón, Jose Juan, and Sánchez, María-José

Subjects
Quantitative Biology - Quantitative Methods
Abstract

We assessed the validity of one of the most frequently used methods to estimate cancer incidence, on the basis of cancer mortality data and the incidence-to-mortality ratio IMR, the IMR method. Using the previous 15 year cancer mortality time series, we derived the expected yearly number of cancer cases in the period 2004 to 2013 for six cancer sites for each sex. Generalized linear mixed models, including a polynomial function for the year of death and smoothing splines for age, were adjusted. Models were fitted under a Bayesian framework based on Markov chain Monte Carlo methods. The IMR method was applied to five scenarios reflecting different assumptions regarding the behavior of the IMR. We compared incident cases estimated with the IMR method to observed cases diagnosed in 2004 to 2013 in Granada. A goodness-of-fit GOF indicator was formulated to determine the best estimation scenario. The relative differences between the observed and predicted numbers of cancer cases were less than 10 percent for most cancer sites. The constant assumption for the IMR trend provided the best GOF for colon, rectal, lung, bladder, and stomach cancers in men and colon, rectum, breast, and corpus uteri in women.

Published
2024
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2. Study of a cubic cavity resonator for gravitational waves detection in the microwave frequency range

Author

Navarro, Pablo, Gimeno, Benito, Monzó-Cabrera, Juan, Díaz-Morcillo, Alejandro, and Blas, Diego

Subjects
High Energy Physics - Phenomenology, General Relativity and Quantum Cosmology, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The direct detection of gravitational waves (GWs) of frequencies above MHz has recently received considerable attention. In this work we present a precise study of the reach of a cubic cavity resonator to GWs in the microwave range, using for the first time tools allowing to perform realistic simulations. Concretely, the BI-RME 3D method, which allows us to obtain not only the detected power but also the detected voltage (magnitude and phase), is used here. After analyzing three cubic cavities for different frequencies and working simultaneously with three different degenerate modes at each cavity, we conclude that the sensitivity of the experiment is strongly dependent on the polarization and incidence angle of the GW. The presented experiment can reach sensitivities up to $ 1 \cdot 10^{-19}$ at 100\, MHz, $ 2 \cdot 10^{-20}$ at 1\, GHz, and $ 6 \cdot 10^{-19}$ at 10\, GHz for optimal angles and polarizations, and where in all cases we assumed an integration time of $\Delta t = 1$ ms. These results provide a strong case for further developing the use of cavities to detect GWs. Moreover, the possibility of analyzing the detected voltage (magnitude and phase) opens a new interferometric detection scheme based on the combination of the detected signals from multiple cavities., Comment: 26 pages, 12 figures; v2 matches published version; v3 typo fixed

Published
2023

5. Exposure to residential traffic and trajectories of unhealthy ageing: results from a nationally-representative cohort of older adults

Author

del Río, Sergio Gómez, Plans-Beriso, Elena, Ramis, Rebeca, Ortolá, Rosario, Pastor, Roberto, Sotos-Prieto, Mercedes, Castelló, Adela, Requena, Rocío Olmedo, Moleón, José Juan Jiménez, Félix, Borja María Fernández, Muriel, Alfonso, Miret, Marta, Mateos, Jose Luis Ayuso, Choi, Yoon-Hyeong, Rodríguez-Artalejo, Fernando, Fernández-Navarro, Pablo, and García-Esquinas, Esther

Published
2024
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8. Spanish registry of hemoglobinopathies and rare anemias (REHem-AR): demographics, complications, and management of patients with β-thalassemia

Author

Bardón-Cancho, Eduardo J., Marco-Sánchez, José Manuel, Benéitez-Pastor, David, Payán-Pernía, Salvador, Llobet, Anna Ruiz, Berrueco, Rubén, García-Morin, Marina, Beléndez, Cristina, Senent, Leonor, Acosta, María José Ortega, Pleguezuelos, Irene Peláez, Velasco, Pablo, Collado, Anna, Moreno-Carbonell, Marta, Argilés, Bienvenida, de Soto, Inmaculada Pérez, del Mar Bermúdez, María, Salido Fiérrez, Eduardo J., Blanco-Álvarez, Adoración, Navarro, Pablo González, and Cela, Elena

Published
2024
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11. Autonomic Architecture for Big Data Performance Optimization

Author

Genkin, Mikhail, Dehne, Frank, Shahmirza, Anousheh, Navarro, Pablo, and Zhou, Siyu

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing, Computer Science - Artificial Intelligence
Abstract

The big data software stack based on Apache Spark and Hadoop has become mission critical in many enterprises. Performance of Spark and Hadoop jobs depends on a large number of configuration settings. Manual tuning is expensive and brittle. There have been prior efforts to develop on-line and off-line automatic tuning approaches to make the big data stack less dependent on manual tuning. These, however, demonstrated only modest performance improvements with very simple, single-user workloads on small data sets. This paper presents KERMIT - the autonomic architecture for big data capable of automatically tuning Apache Spark and Hadoop on-line, and achieving performance results 30% faster than rule-of-thumb tuning by a human administrator and up to 92% as fast as the fastest possible tuning established by performing an exhaustive search of the tuning parameter space. KERMIT can detect important workload changes with up to 99% accuracy, and predict future workload types with up to 96% accuracy. It is capable of identifying and classifying complex multi-user workloads without being explicitly trained on examples of these workloads. It does not rely on the past workload history to predict the future workload classes and their associated performance. KERMIT can identify and learn new workload classes, and adapt to workload drift, without human intervention.

Published
2023

13. Autonomic Architecture for Big Data Performance Optimization

Author

Genkin, Mikhail, Dehne, Frank, Shahmirza, Anousheh, Navarro, Pablo, Zhou, Siyu, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, and Arai, Kohei, editor

Published
2024
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14. Civil Architecture of Maestrazgo, the Castellote House: Graphic Processes for Its Knowledge

Author

Sender Contell, Marina, Ribera, Manuel Giménez, Piqueras, Teresa Gil, Navarro, Pablo Rodriguez, Tosi, Francesca, Editor-in-Chief, Germak, Claudio, Series Editor, Zurlo, Francesco, Series Editor, Jinyi, Zhi, Series Editor, Pozzatti Amadori, Marilaine, Series Editor, Caon, Maurizio, Series Editor, Hermida González, Luis, editor, Xavier, João Pedro, editor, Pernas Alonso, Inés, editor, and Losada Pérez, Carlos, editor

Published
2024
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21. Correction to: Spanish registry of hemoglobinopathies and rare anemias (REHem- AR): demographics, complications, and management of patients with β-thalassemia

Author

Bardón-Cancho, Eduardo J., Marco-Sánchez, José Manuel, Benéitez-Pastor, David, Payán-Pernía, Salvador, Llobet, Anna Ruiz, Berrueco, Rubén, García-Morin, Marina, Beléndez, Cristina, Senent, Leonor, Acosta, María José Ortega, Pleguezuelos, Irene Peláez, Velasco, Pablo, Collado, Anna, Moreno-Carbonell, Marta, Argilés, Bienvenida, de Soto, Inmaculada Pérez, del Mar Bermúdez, María, Salido Fiérrez, Eduardo J., Blanco-Álvarez, Adoración, Navarro, Pablo González, and Cela, Elena

Published
2024
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22. Analysis of Pre-Service Foreign Language Teachers' Incorrect Articulations: Frequency, Influence on Communication, and a Specific Corrective Strategy

Author

Hunt-Gómez, Coral I. and Navarro-Pablo, Macarena

Abstract

English Foreign Language (EFL) teachers need to be especially aware of their own articulatory errors and to manage strategies to overcome them. A specific corrective strategy using phonetic notation to destabilise the most recurrent articulatory errors to be applied to Spanish pre-service English Primary School teachers is presented. Firstly, the presence of incorrectly articulated sounds in a corpus of 238 minutes of recorded improvised production of 34 pre-service EFL teachers was identified. Incorrect articulations were classified in two groups, those that presented a higher frequency were classified as fossilised errors and those appearing only once were considered mistakes. A categorisation of the most frequent articulatory errors and their possible origins was offered. Errors were also examined attending the effect they posed on communication, if they hindered it, they were considered unintelligible. Results showed that more than 80% of fossilised incorrect articulations were perfectly understandable and did not disrupt communication. Even if these results can be considered positive, research shows that pronunciation highly influences the learning process of other skills, and that it affects learners in terms of confidence, social and work advancement. Therefore, to get rid of their own fossilised errors, future teachers need effective pronunciation skills training strategies. For that reason, a specific error corrective strategy based on phonetic notation and self-learning is proposed.

Published
2020

23. Hospital variation in quality indicators for patient blood management in total knee and hip arthroplasty: a retrospective cohort study

Author

Azparren, Alicia Aranguren, Gosálbez, Ana Abad, Faura, Ana, Plaza, Ana morales de la, Puig, Ana Ruiz, Caballero, Angel, Lavado, Ángel, Montserrat, Cadena Serramitja, Jericó, Carlos, Sanabria, Carmen Elena, Escribano, Cristina Martinez, Paraschiv, Dra.Violeta Turcu, Cerezo, Estefania, Méndez, Esther, Ponce, Esther Sancho, Ribas, Esther Vila, Parga, Eva Bassas, Jimeno Demuth, Francisco José, Moreno-Jimenez, Gemma, Montero, Gerardo Gómez, Cabezón, Gonzalo Azparren, Graciani, Ignacio de la Fuente, Ruiz, Inocencia Fornet, Martínez, Isabel Castrillo, Ortega Lucas, J. Enrique, Gorricho, Javier, Estévez, Javier Mata, Morales, Jordi Colomina, García-Erce, José Antonio, Campuzano Garcia, José Luis, Gonzalez-Rodriguez, Jose Luis, García-Gala, Jose M., Vagace, José Manuel, Ávila Idrovo, Laura Francisca, Almirante, Laura Martínez, Gonzalez del Castillo, Luz María, Pisano Blanco, M Aranzazu, Campos Peláez, M Isabel, Herranz Andrés, M Pilar, Conejo, Manel Romero, Ruiz Dãíaz, Maria Pilar, Díaz Comino, Maria Raquel, Navarro, Marina Canales, Albacar-Ingla, Marta, Mesa, Miguel Rey, Riera, Montserrat Torra, Ibarra, N., Pons, Natalia Gallench, López, Nuria Ruiz, Navarro, Pablo González, Austenrritt, Pamela Millacoy, Sorolla, Patricia Marzal, Perez, Pilar Arribas, Solves, Pilar, París, Raquel Tolós, Morell, Reis Drudis, Robles-Cedeño, René, Upegui Villegas, Rosa I., Alvarez, Sonsoles Aragón, Planella, Teresa, Dueñas, Virginia, Nuñez, Yolanda Cabanillas, Gómez, Yolanda Palacios, Garcia-Casanovas, Albert, Bisbe, Elvira, Garcia-Altes, Anna, Vizoso, Adria, Duran-Jorda, Xavier, Sanchez-Pedrosa, Guillermo, Barquero, Marta, Colomina, Maria J., and Basora, Misericordia

Published
2024
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28. Optimizing Racing Wheelchair Design Through Coupled Biomechanical-Mechanical Simulation

Author

Loiseau, Adrien, Marsan, Thibault, Navarro, Pablo, Watier, Bruno, Landon, Yann, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Haddar, Mohamed, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Gerbino, Salvatore, editor, Lanzotti, Antonio, editor, Martorelli, Massimo, editor, Mirálbes Buil, Ramón, editor, Rizzi, Caterina, editor, and Roucoules, Lionel, editor

Published
2023
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29. The Use of Digital Resources and Materials in and outside the Bilingual Classroom

Author

Navarro-Pablo, Macarena, López-Gándara, Yiyi, and García-Jiménez, Eduardo

Abstract

Research on the integration of digital resources and materials in CLIL contexts is still scant. This article presents the results of a study carried out in eight schools in the province of Seville. Questionnaires and interviews were used to collect the data regarding CLIL teachers' and learners' opinions on the intergration of digital resources and materials in the classroom. The aims of this study are: 1) To analyse teachers' and learners' perceptions on the integration of digital resources and materials in the CLIL classroom; 2) To analyse how the educational stage affects teachers' and learners' perceptions on this use; 3) To analyse the type of digital resources and materials in English that learners use outside the classroom. The following analyses have been carried out: Categorical Principal Components Analysis; Mann-Whitney U test; qualitative content analysis; finally, Pearson correlation coefficients were calculated. Results show that there are discrepancies between teachers' and learners' perceptions regarding the use of digital resources and materials in the classroom; and that these perceptions are affected by the educational stage. This study concludes that the type of resources and materials that learners use outside the classroom is determined by those used in the classroom. However, at home, they are used differently, which is indicative of the need to adapt classroom practices to learners' own independent uses.

Published
2019

36. A role for non-coding Tsix transcription in partitioning chromatin domains within the mouse X-inactivation centre

Author

Navarro Pablo, Chantalat Sophie, Foglio Mario, Chureau Corinne, Vigneau Sébastien, Clerc Philippe, Avner Philip, and Rougeulle Claire

Subjects
Genetics, QH426-470
Abstract

Abstract Background Delimiting distinct chromatin domains is essential for temporal and spatial regulation of gene expression. Within the X-inactivation centre region (Xic), the Xist locus, which triggers X-inactivation, is juxtaposed to a large domain of H3K27 trimethylation (H3K27me3). Results We describe here that developmentally regulated transcription of Tsix, a crucial non-coding antisense to Xist, is required to block the spreading of the H3K27me3 domain to the adjacent H3K4me2-rich Xist region. Analyses of a series of distinct Tsix mutations suggest that the underlying mechanism involves the RNA Polymerase II accumulating at the Tsix 3'-end. Furthermore, we report additional unexpected long-range effects of Tsix on the distal sub-region of the Xic, involved in Xic-Xic trans-interactions. Conclusion These data point toward a role for transcription of non-coding RNAs as a developmental strategy for the establishment of functionally distinct domains within the mammalian genome.

Published
2009
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38. Modifying vacancy defects during systematic disordering of the Cr2AlC nano-lamellar system

Author

Salgado Cabaco, J., (0000-0001-7933-7295) Liedke, M. O., Navarro Pablo, J., (0009-0003-0366-9690) Ganss, F., Magen, C., Ricardo Ibarra, M., (0000-0001-5295-2554) Kentsch, U., (0000-0003-3674-0767) Butterling, M., (0000-0001-7575-3961) Wagner, A., (0000-0002-4955-515X) Lindner, J., (0000-0003-3893-9630) Faßbender, J., Leyens, C., Boucher, R., Bali, R., Salgado Cabaco, J., (0000-0001-7933-7295) Liedke, M. O., Navarro Pablo, J., (0009-0003-0366-9690) Ganss, F., Magen, C., Ricardo Ibarra, M., (0000-0001-5295-2554) Kentsch, U., (0000-0003-3674-0767) Butterling, M., (0000-0001-7575-3961) Wagner, A., (0000-0002-4955-515X) Lindner, J., (0000-0003-3893-9630) Faßbender, J., Leyens, C., Boucher, R., and Bali, R.

Abstract

The layered structure of MAX phases is associated with a number of functional properties and is the subject of extensive research. While the unit-cell layers of these structures have been well studied, much less is known about the distribution and manipulation of point defects within them. Here, we selected the prototype Cr2AlC system and, using variable energy positron beams, observed Doppler broadening and positron annihilation lifetimes to track the evolution of defects caused by the penetration of energetic transition metal ions (Co+ and Mn+) and noble gas ions (Ar+ and Ne+). In all cases an overall reduction of the open-volume defect concentration is observed post-irradiation. Atomic displacements induced by the penetrating ions drastically modify the defect distribution: the concentration of agglomerates of 9–15 vacancies (corresponding to positron lifetimes of 335–450 ps) in the precursor [Cr2C/Al]n layers is suppressed, whereas Al mono- and Al-Cr di-vacancy (lifetimes 217–231 ps) concentrations are enhanced. This breakdown of large defects into point defects scales with atomic displacements and is largely independent of the penetrating ion species, providing insights into the manipulation of point defects in nano-layered systems.

Published
2025

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