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We have previously shown that self-initiation improves accuracy in visual Short Term Memory (STM) (Loyola-Navarro et al., 2021). Nevertheless, we don't know if these results are generalizable to Working Memory (WM) tasks, since our previous design has little ecological validity, and thus our results are not easily generalizable. Besides, it is not clear whether this effect is multimodal, or if it is specific to the visual domain. To prove if self-initiation improves STM and WM, we will recruit undergrade students and ask them to engage in two Digit Span experiments with varying initiation styles (i.e. encoding). We designed two initiation styles: Automatic (Auto) and Self-initiated presentation. Auto consisted of the automatic presentation of the digits, 550 ms after a cue. Self-initiated consisted of the presentation of the digits 550 ms after the subject pressed the spacebar. To asses the multimodality of the effect, stimulus will be presented in the visual and auditory modality. Experiment 1 will assess the efects of initiation styles and sensory modality using a Forward Digit Span task, while in Experiment 2 we will use a Backward Digit Span task. The experiments will involve a 2x2 factorial repeated measures design. We will assess the effects of self-initiation and sensory modalities on Accuracy (proportion of correct answers) and Response times using two Generalized Linear Mixed Models per experiment. Pilot data retrieved from 19 undergraduate students shows no effect of initiation style nor modality on Forward Digit Span Accuracy, while an effect of initiation style on Backward Digit Span Acurracy in the visual modality only.

The 2-Minute Step Test (2MST) has been presented as an alternative to the 6-Minute Walk Test (6MWT) based on the association between the two tests in older adults; however, some authors propose that it should not be a substitute but rather a complement to the latter in the fitness evaluation. Specifically, in coronary disease, despite the potential and clinical utility of 2MST, the relationship of both tests in this population is unknown. This study aimed to determine the relationship between 6MWT and 2MST and to explore the relationship of biodemographic factors for both tests in subjects with treated coronary artery disease. For this, the 6MWT and the 2MST were applied to patients with coronary artery disease treated in 6 hospitals in Chile between May 2019 and February 2020. Additionally, lower limb strength was assessed by a chair-stand test, grip strength was assessed by a dynamometer, and physical measurements were applied. In total, 163 participants underwent both tests (average age = 58.7 ± 9.8 years; 73.6% men; 64.4% revascularized by angioplasty; 28.2% revascularized by surgery, and 7.4% treated by drugs or thrombolysis). Heart rate was higher at the end of the 6MWT, while the perception of effort was greater at the end of the 2MST. There was a weak positive correlation between the 6MWT and the 2MST in subjects with treated coronary disease (r = 0.28, p = 0.0003). While age (r = –0.27), weight (r = 0.25), height (r = 0.49), and strength of both lower limbs (r = 0.41) and grip strength (r = 0.53) correlated weakly or moderately to the covered distance in 6MWT, the number of steps by the 2MST correlated only weakly to height (r = 0.23), lower limb strength (r = 0.34), and grip strength (r = 0.34). Age, weight, height, lower limb strength, and grip strength would explain better the meters walked in the 6MWT than the steps achieved in the 2MST. With these findings, we can conclude that, in patients with treated coronary artery disease, it does not seem advisable to replace 6MWT with 2MST when it is possible to do so. Additionally, the 2MST may provide additional information in the fitness evaluation. However, the usefulness of 2MST in this population needs to be further studied.

En el presente estudio se analizan los efectos derivados de la pandemia de Covid-19 sobre la situación laboral y el bienestar de los trabajadores. Para evaluar estos efectos, se elaboró un instrumento que constaba de un cuestionario de datos sociodemográficos, laborales y situaciones derivadas de la pandemia, y las escalas de Significación Vital (Morgan y Farsides, 2008), Satisfacción con la vida (versión adaptada al español por Atienza y cols., 2000), Afectividad Positiva y Negativa (adaptación escala corta de Flores-Kanter y Medrano, 2015) y Trabajo Significativo (adaptación al español de Duarte-Lores y cols., 2021). En el estudio participaron 120 personas. Los resultados muestran que las personas desempleadas muestran menor satisfacción con la vida y significación vital, y más afecto negativo que los participantes con contratos de trabajo indefinidos. Así como, los cambios producidos en la situación laboral de los participantes presentando menor nivel de Afecto Positivo, Significación vital, Satisfacción con la vida y mayor Afecto Negativo en los participantes que si sufrieron cambios. Por último, los resultados también muestran menor Afecto Positivo y significación con el trabajo las personas que han presentado dificultades de salud derivadas de la pandemia por Covid-19. This study analyzes the effects of the Covid-19 pandemic on the employment situation and the well-being of workers. To evaluate these effects, an instrument was developed that consisted of a questionnaire of sociodemographic, occupational and situation data derived from the pandemic, and the Vital Significance scales (Morgan and Farsides, 2008), Satisfaction with life (version adapted to Spanish by Atienza et al., 2000), Positive and Negative Affectivity (short scale adaptation of Flores-Kanter and Medrano, 2015) and Significant Work (adaptation to Spanish of Duarte-Lores et al., 2021). 120 subjects participated in the study. The results show that unemployed people show less satisfaction with life and vital significance, and more negative affect than participants with indefinite employment contracts. As well as, the changes produced in the occupational situation of the participants presenting a lower level of Positive Affect, Vital Significance, Satisfaction with life and greater Negative Affect in the participants who did undergo changes. Finally, the results also show less Positive Affect and significance with work for people who have presented health difficulties derived from the Covid-19 pandemic.

El trabajo consiste en el análisis del consumo de la televisión tradicional y el de la plataforma digital de YouTube. El principal objetivo es confirmar si el gran sustituto de la televisión es YouTube. Para ello se han elaborado dos estudios. Por un lado, uno sobre los diferentes contenidos tanto en televisión como en YouTube, y, por otro lado, otro comparando las distintas audiencias en ambas producciones audiovisuales. En ellos, se demuestra que el auge de las plataformas digitales sí perjudican a las audiencias de televisión. Sin embargo, se ha elaborado un tercer estudio para comprobar si YT y la TV pueden llegar a ser aliados. En este caso, ha sido objeto de estudio el programa de televisión Top Gamers Academy, obteniendo como resultado: una alianza fallida. The work consists in the analysis of the consumption of traditional television and YouTube digital platform. The main objective is to confirm if the substitute for television is YouTube. For this reason, two studies have been carried out. On the one hand, one about the different content on television and on YouTube, and, on the other hand, another comparing the different audiences in both audiovisual productions. It is shown that the rise of digital platforms harms television audiences. However, a third study has been carried out to prove if YT and TV can become allies. In this case, the Top Gamers Academy television program has been the topic of the study obtaining as a result: a failed alliance.

En este libro se presentan un conjunto de ensayos que discuten varios aspectos centrales a la relación entre pandemia y educación, que se inician en una mirada desde lo macro, examinando la dimensión política y la educación.

El presente trabajo se basa en una traducción especializada en el sector de calzado. Primero de todo, se redactará, a modo de contextualización, un marco teórico con diferentes cuestiones: la historia del calzado, panorama actual del sector del calzado en España, cómo ha afectado el Covid-19 a este sector, la traducción técnica y qué es un Libro Blanco. A continuación, se llevará a cabo una traducción francés-español de unas 5.000 palabras de dos textos diferentes de dicho ámbito y se cumplimentará un glosario con toda la terminología relevante. Asimismo, se realizará un análisis exhaustivo sobre el resultado final de la traducción y la terminología especializada que contiene. Finalmente, el trabajo concluirá con una visión general de lo hallado a lo largo del mismo.

Purpose and justification: To design and validate a questionnaire on the satisfaction with the environmental and food factor surveillance and control carried out by health authorities of the economic operators subjected to such control.Method and materials: Designing a descriptive, cross-sectional study for the validation of a questionnaire on the economic operator’s satisfaction with the official control agent’s performance.Location: The study was conducted in the Aljarafe-Sevilla Norte Primary Care Health District, which encompasses populations in Seville and Huelva. The inspection activity is carried out by 58 official control agents, who conduct inspections at 9,689 food companies in the Autonomous Community of Andalusia.Participants: Telephone surveys were given to a random sample of 675 economic operators which were subjected to sanitary control during the month of July 2019.Method: The questionnaire, which was designed by a group of experts, consisted of 12 closed-ended questions on a numerical scale and 1 open-ended question. Its construct validity, discriminating capacity and internal consistency were ascertained.Results: Two factors—“technical quality” and “organizational quality”—were identified, which explain 52.45 % of the variance. The questionnaire has internal consistency (Cronbach ́s alpha: 0.808).Conclusions: The questionnaire has sufficient psychometric properties to be considered a useful and reliable tool for measuring the satisfaction of economic operators with the sanitary control carried out by official control agents. Justificación y objetivo: Diseñar y validar un cuestionario de satisfacción de la actividad de vigilancia y control de factores ambientales y alimentarios ejercida por las autoridades sanitarias y percibida por los operadores económicos sometidos a ella.Material y método: Diseño del estudio descriptivo transversal de validación de un cuestionario de satisfacción del operador económico respecto a la actuación del agente de control oficial.Emplazamiento: El ámbito de estudio fue el Distrito Sanitario de Atención Primaria Aljarafe-Sevilla Norte, que comprende poblaciones de Sevilla y Huelva. La actividad la prestan 58 agentes de control oficial que realizan controles en 9 689 empresas alimentarias comunitarias.Participantes: Se realizaron encuestas telefónicas a una muestra aleatoria de 675 operadores económicos sometidos a control sanitario durante el mes de julio de 2019.Método: El cuestionario fue diseñado por un grupo de expertos, constando de 12 preguntas cerradas con escala numérica y una pregunta abierta. Se analizó la validez de constructo, capacidad discriminante y consistencia interna.Resultados: Se identificaron dos factores, “calidad técnica” y “calidad organizativa”, que explican el 52,45 % de la varianza, con consistencia interna (alfa de Cronbach 0,808).Conclusiones: El cuestionario reúne suficientes propiedades psicométricas como para que pueda ser considerado una herramienta útil y fiable para medir la satisfacción de los operadores económicos en relación a las actuaciones del agente de control oficial en el control sanitario. Justificação e objetivo: Elaborar e validar um questionário de satisfação para a vigilância e controle dos fatores ambientais e alimentares realizado pelas autoridades sanitárias à perceção dos operadores económicos a ele sujeitos.Material e método: Desenho de estudo descritivo transversal, para validação de questionário de satisfação do operador económico, quanto ao desempenho do agente oficial de controlo.Âmbito: A área em estudo foi o Distrito Sanitário de Cuidados de Saúde Primários de Aljarafe-Sevilla Norte, que inclui as cidades de Sevilha e Huelva. A atividade é realizada por 58 agentes oficiais de controlo, que realizam controlos em 9.689 empresas comunitárias de alimentos.Participantes: Foram realizadas contactos telefónicos a uma amostra aleatória de 675 operadores económicos submetidos ao controle sanitário durante o mês de julho de 2019.Método: O questionário foi elaborado por um grupo de especialistas, composto por 12 questões fechadas com escala numérica e uma questão aberta. Foram analisadas a validade do constructo, capacidade discriminante e consistência interna.Resultados: Foram identificados dois fatores, “qualidade técnica” e “qualidade organizacional” que explicam 52,45 % da variância, com consistência interna (alfa de Cronbach 0,808).Conclusões: O questionário possui propriedades psicométricas suficientes para ser considerado uma ferramenta útil e confiável para medir a satisfação dos operadores económicos, em relação às ações do agente de controlo oficial pelo controlo sanitário.

Justificación y objetivo: Diseñar y validar un cuestionario de satisfacción de la actividad de vigilancia y control de factores ambientales y alimentarios ejercida por las autoridades sanitarias y percibida por los operadores económicos sometidos a ella.Material y método: Diseño del estudio descriptivo transversal de validación de un cuestionario de satisfacción del operador económico respecto a la actuación del agente de control oficial.Emplazamiento: El ámbito de estudio fue el Distrito Sanitario de Atención Primaria Aljarafe-Sevilla Norte, que comprende poblaciones de Sevilla y Huelva. La actividad la prestan 58 agentes de control oficial que realizan controles en 9 689 empresas alimentarias comunitarias.Participantes: Se realizaron encuestas telefónicas a una muestra aleatoria de 675 operadores económicos sometidos a control sanitario durante el mes de julio de 2019.Método: El cuestionario fue diseñado por un grupo de expertos, constando de 12 preguntas cerradas con escala numérica y una pregunta abierta. Se analizó la validez de constructo, capacidad discriminante y consistencia interna.Resultados: Se identificaron dos factores, “calidad técnica” y “calidad organizativa”, que explican el 52,45 % de la varianza, con consistencia interna (alfa de Cronbach 0,808).Conclusiones: El cuestionario reúne suficientes propiedades psicométricas como para que pueda ser considerado una herramienta útil y fiable para medir la satisfacción de los operadores económicos en relación a las actuaciones del agente de control oficial en el control sanitario. Justificação e objetivo: Elaborar e validar um questionário de satisfação para a vigilância e controle dos fatores ambientais e alimentares realizado pelas autoridades sanitárias à perceção dos operadores económicos a ele sujeitos.Material e método: Desenho de estudo descritivo transversal, para validação de questionário de satisfação do operador económico, quanto ao desempenho do agente oficial de controlo.Âmbito: A área em estudo foi o Distrito Sanitário de Cuidados de Saúde Primários de Aljarafe-Sevilla Norte, que inclui as cidades de Sevilha e Huelva. A atividade é realizada por 58 agentes oficiais de controlo, que realizam controlos em 9.689 empresas comunitárias de alimentos.Participantes: Foram realizadas contactos telefónicos a uma amostra aleatória de 675 operadores económicos submetidos ao controle sanitário durante o mês de julho de 2019.Método: O questionário foi elaborado por um grupo de especialistas, composto por 12 questões fechadas com escala numérica e uma questão aberta. Foram analisadas a validade do constructo, capacidade discriminante e consistência interna.Resultados: Foram identificados dois fatores, “qualidade técnica” e “qualidade organizacional” que explicam 52,45 % da variância, com consistência interna (alfa de Cronbach 0,808).Conclusões: O questionário possui propriedades psicométricas suficientes para ser considerado uma ferramenta útil e confiável para medir a satisfação dos operadores económicos, em relação às ações do agente de controlo oficial pelo controlo sanitário. Purpose and justification: To design and validate a questionnaire on the satisfaction with the environmental and food factor surveillance and control carried out by health authorities of the economic operators subjected to such control.Method and materials: Designing a descriptive, cross-sectional study for the validation of a questionnaire on the economic operator’s satisfaction with the official control agent’s performance.Location: The study was conducted in the Aljarafe-Sevilla Norte Primary Care Health District, which encompasses populations in Seville and Huelva. The inspection activity is carried out by 58 official control agents, who conduct inspections at 9,689 food companies in the Autonomous Community of Andalusia.Participants: Telephone surveys were given to a random sample of 675 economic operators which were subjected to sanitary control during the month of July 2019.Method: The questionnaire, which was designed by a group of experts, consisted of 12 closed-ended questions on a numerical scale and 1 open-ended question. Its construct validity, discriminating capacity and internal consistency were ascertained.Results: Two factors—“technical quality” and “organizational quality”—were identified, which explain 52.45 % of the variance. The questionnaire has internal consistency (Cronbach ́s alpha: 0.808).Conclusions: The questionnaire has sufficient psychometric properties to be considered a useful and reliable tool for measuring the satisfaction of economic operators with the sanitary control carried out by official control agents.

Este proyecto consiste en la creación y el desarrollo de la marca Kawati, la cual se dedica a la venta de artículos personalizados a mano, centrándose de momento en bolsas y zapatillas de tela, pero con vistas a ampliar la oferta de productos a otros muchos, todos ellos de carácter artesanal y personalizado. Para ello, se ha llevado a cabo un estudio de mercado acerca del sector en el que se pretende incidir, la competencia y el público al que se desea captar, para así poder tomar decisiones acertadas en cuanto a la identidad de marca, el branding y toda la identidad visual corporativa. Se han elegido minuciosamente cada uno de los detalles que conforman una marca, de manera eficaz y coherente para que transmitan unos mismos valores, reforzando así la identidad de marca desde todos los puntos posibles para mejorar su inclusión en el mercado. Una vez creada y desarrollada la marca como tal, se ha procedido a tomar decisiones en todo el marco digital, se han creado los perfiles en las diferentes redes sociales en las que se mueve el público de Kawati y, además, se ha generado contenido para las mismas. Se ha desarrollado una página web para la marca, completamente visual e intuitiva, que sirve como catálogo de productos. También en el ámbito de internet y social media, se han abordado acciones más concretas y puntuales, como los sorteos o las colaboraciones. Se ha generando un contenido acorde con la identidad elegida para Kawati, y llamativo para el público objetivo de la misma. De esta manera, se pretende lograr el aumento de notoriedad de la marca, la coherencia dentro de la misma y en definitiva, el éxito. This project consists of the creation and development of the Kawati brand, which is dedicated to the sale of personalized items by hand, focusing for the moment on bags and shoes, but with a view to expanding the product offering to many others, all of them handmade and personalized. To do this, a market study has been carried out on the sector in which it is intended to influence, the competition and the audience you want to attract, in order to make the right decisions regarding brand identity, branding and all corporate visual identity. Each of the details that make up a brand have been carefully chosen, effectively and consistently so that they convey the same values, thus reinforcing the brand identity from all possible points to improve its inclusion in the market. Once the brand is created and developed, decisions have been made across the entire digital framework, The profiles have been created in the different social networks in which the Kawati public moves and, in addition, content has been generated for them. A website has been developed for the brand, completely visual and intuitive, which serves as a product catalog. Also in the field of internet and social media, more specific actions have been taken, like sweepstakes or collaborations. Content has been generated according to the identity chosen for Kawati, and eye-catching for the target audience of it. In this way, the aim is to increase the brand's notoriety, consistency within it and ultimately, success. Universidad de Sevilla. Grado en Publicidad y Relaciones Públicas

Hoy en día es muy importante que las empresas trabajen sus sitios web en busca de mejorar su posición en los buscadores (Google, Yahoo, etc.), para ello emplean una serie de técnicas y herramientas que aumentan la visibilidad del establecimiento o negocio según su situación geográfica (SEO local). El objetivo del trabajo es realizar un experimento para observar la evolución del SEO local de las ubicaciones de una cadena de supermercados en la ciudad de València en los servicios de búsqueda y mapas de Google. Para ello se seleccionaron 53 supermercados de los que Google no disponía fotografías propias y se creó un grupo control al que no se les aplicó ningún tratamiento. Este grupo estaba formado por 14 supermercados, seleccionados en base a criterios geográficos (distritos de la ciudad de València), características propias de los locales (metros cuadrados, parking propio) y densidad comercial. Como indicadores de evolución se usaron las visualizaciones (de la búsqueda o de Maps), las búsquedas (directas e indirectas) y acciones (llamada, visita al sitio web y solicitud de indicaciones). Se observó una mejora en los tres indicadores con una repercusión de 3.5 millones de visualizaciones, 3,3 millones de búsquedas y 1,9 millones de acciones de los usuarios más que en 2019.

In this work, we show that TGF‐β produced by colorectal cancer cells activates pericytes that in turn promote their tumorigenic properties through the release of soluble factors, including IGFBP‐3, with a prominent role in cancer cell migration and invasion. Moreover, co‐implantation of colorectal cancer cells and pericytes in immunodeficient mice increased tumor growth., The crosstalk between cancer cells and the tumor microenvironment has been implicated in cancer progression and metastasis. Fibroblasts and immune cells are widely known to be attracted to and modified by cancer cells. However, the role of pericytes in the tumor microenvironment beyond endothelium stabilization is poorly understood. Here, we report that pericytes promoted colorectal cancer (CRC) cell proliferation, migration, invasion, stemness, and chemoresistance in vitro, as well as tumor growth in a xenograft CRC model. We demonstrate that coculture with human CRC cells induced broad transcriptomic changes in pericytes, mostly associated with TGF‐β receptor activation. The prognostic value of a TGF‐β response signature in pericytes was analyzed in CRC patient data sets. This signature was found to be a good predictor of CRC relapse. Moreover, in response to stimulation by CRC cells, pericytes expressed high levels of TGF‐β1, initiating an autocrine activation loop. Investigation of secreted mediators and underlying molecular mechanisms revealed that IGFBP‐3 is a key paracrine factor from activated pericytes affecting CRC cell migration and invasion. In summary, we demonstrate that the interplay between pericytes and CRC cells triggers a vicious cycle that stimulates pericyte cytokine secretion, in turn increasing CRC cell tumorigenic properties. Overall, we provide another example of how cancer cells can manipulate the tumor microenvironment.