1. Effect of romosozumab in premenopausal women with severe osteoporosis and anorexia nervosa
- Author
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Kazuki Fujimoto, Narumi Maki, Daisuke Hashiba, Toshifumi Maeyama, Ryosuke Nakagawa, Hajime Arai, and Seiji Ohtori
- Subjects
Anorexia nervosa ,Secondary osteoporosis ,Anti-sclerostin antibody ,Bone metabolism ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Objectives: This study aims to investigate the effects of romosozumab on bone mineral density (BMD) and bone metabolism. Methods: In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab. Results: BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab. Conclusions: Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.
- Published
- 2023
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