17 results on '"Narasimha Swamy, S"'
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2. Real-Time, YOLO-Based Intelligent Surveillance and Monitoring System Using Jetson TX2
- Author
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Kumar, Prashant, Narasimha Swamy, S., Kumar, Pramod, Purohit, Gaurav, Raju, Kota Solomon, Xhafa, Fatos, Series Editor, Khanna, Ashish, editor, Gupta, Deepak, editor, Pólkowski, Zdzisław, editor, Bhattacharyya, Siddhartha, editor, and Castillo, Oscar, editor
- Published
- 2021
- Full Text
- View/download PDF
3. An Edge Computing-Assisted Internet of Things-Based Secure Smart Home
- Author
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Narasimha Swamy, S., primary, Shivanarayanamurthy, P., additional, Purohit, Gaurav, additional, and Raju, Kota Solomon, additional
- Published
- 2022
- Full Text
- View/download PDF
4. Real-Time Concrete Damage Detection Using Deep Learning for High Rise Structures
- Author
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Prashant Kumar, Supraja Batchu, Narasimha Swamy S., and Solomon Raju Kota
- Subjects
Cracks recognition using machine learning ,cracks recognition using deep learning ,framework for real-time multi-drone concrete damage (crack & spall) detection ,layered architecture of YOLO-v3 ,real-time cracks detection ,understanding the YOLO-v3 ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Nowadays, the number of aging high-rise civil structures is growing throughout the world, and most of them use concrete as a building material. Concrete may lose its strength due to continuous loading and environmental impacts. As a result, damage (crack and spall) may occur on the exterior surface of the structure. Whenever these deformities are left unexplored and untreated, the integrity of the structure may be compromised. Therefore, regular maintenance of the structure is needed. Some previous vision-based studies have used a drone as a vehicle to capture and record the current state of the structure. Later, captured videos and images were analyzed to determine damage using object classification, localization, and segmentation methods. Also, in a few studies, drones relay the collected data to the server using a wireless medium. However, the developed systems are very complex, time-intensive, and require high bandwidth. To address these problems, this paper uses the edge computing principle to propose a real-time multi-drone damage detection system using one of the advance deep learning models called You Look Only Once-version3 (YOLO-v3) for high-rise civil structures. The proposed system uses Jetson-TX2 as a hardware platform to run YOLO-v3 and is deployed on Pixhawk’s hardware standards-based open source hexacopter drone. During a coordinated survey, if the damage is observed, the Jetson-TX2 on-board, after processing, sends only the damage-related information to the server that resides on the ground through the Wi-Fi channel. Our proposed system is evaluated on a dataset containing 800 ( $480\times480$ pixels) images of different types of damage, collected from multiple structures of CSIR-CEERI, Pilani. Manually annotated images are used for the training and testing of the modified YOLO-v3 classifier. As a result, the proposed approach offers reliable performance with an accuracy of 94.24% and can process an image in 0.033 seconds.
- Published
- 2021
- Full Text
- View/download PDF
5. Real-Time, YOLO-Based Intelligent Surveillance and Monitoring System Using Jetson TX2
- Author
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Kumar, Prashant, primary, Narasimha Swamy, S., additional, Kumar, Pramod, additional, Purohit, Gaurav, additional, and Raju, Kota Solomon, additional
- Published
- 2021
- Full Text
- View/download PDF
6. Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019:A Systematic Analysis for the Global Burden of Disease Study 2019
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Global Burden of Disease 2019 Cancer Collaboration, Kocarnik, JM, Compton, K, Dean, FE, Fu, W, Gaw, BL, Harvey, JD, Henrikson, HJ, Lu, D, Pennini, A, Xu, R, Ababneh, E, Abbasi-Kangevari, M, Abbastabar, H, Abd-Elsalam, SM, Abdoli, A, Abedi, A, Abidi, H, Abolhassani, H, Adedeji, IA, Adnani, QES, Advani, SM, Afzal, MS, Aghaali, M, Ahinkorah, BO, Ahmad, S, Ahmad, T, Ahmadi, A, Ahmadi, S, Ahmed Rashid, T, Ahmed Salih, Y, Akalu, GT, Aklilu, A, Akram, T, Akunna, CJ, Al Hamad, H, Alahdab, F, Al-Aly, Z, Ali, S, Alimohamadi, Y, Alipour, V, Aljunid, SM, Alkhayyat, M, Almasi-Hashiani, A, Almasri, NA, Al-Maweri, SAA, Almustanyir, S, Alonso, N, Alvis-Guzman, N, Amu, H, Anbesu, EW, Ancuceanu, R, Ansari, F, Ansari-Moghaddam, A, Antwi, MH, Anvari, D, Anyasodor, AE, Aqeel, M, Arabloo, J, Arab-Zozani, M, Aremu, O, Ariffin, H, Aripov, T, Arshad, M, Artaman, A, Arulappan, J, Asemi, Z, Asghari Jafarabadi, M, Ashraf, T, Atorkey, P, Aujayeb, A, Ausloos, M, Awedew, AF, Ayala Quintanilla, BP, Ayenew, T, Azab, MA, Azadnajafabad, S, Azari Jafari, A, Azarian, G, Azzam, AY, Badiye, AD, Bahadory, S, Baig, AA, Baker, JL, Balakrishnan, S, Banach, M, Bärnighausen, TW, Barone-Adesi, F, Barra, F, Barrow, A, Behzadifar, M, Belgaumi, UI, Bezabhe, WMM, Bezabih, YM, Bhagat, DS, Bhagavathula, AS, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhattacharyya, K, Bhojaraja, VS, Bibi, S, Bijani, A, Biondi, A, Bisignano, C, Bjørge, T, Bleyer, A, Blyuss, O, Bolarinwa, OA, Bolla, SR, Braithwaite, D, Brar, A, Brenner, H, Bustamante-Teixeira, MT, Butt, NS, Butt, ZA, Caetano Dos Santos, FL, Cao, Y, Carreras, G, Catalá-López, F, Cembranel, F, Cerin, E, Cernigliaro, A, Chakinala, RC, Chattu, SK, Chattu, VK, Chaturvedi, P, Chimed-Ochir, O, Cho, DY, Christopher, DJ, Chu, D-T, Chung, MT, Conde, J, Cortés, S, Cortesi, PA, Costa, VM, Cunha, AR, Dadras, O, Dagnew, AB, Dahlawi, SMA, Dai, X, Dandona, L, Dandona, R, Darwesh, AM, Das Neves, J, De la Hoz, FP, Demis, AB, Denova-Gutiérrez, E, Dhamnetiya, D, Dhimal, ML, Dhimal, M, Dianatinasab, M, Diaz, D, Djalalinia, S, Do, HP, Doaei, S, Dorostkar, F, Dos Santos Figueiredo, FW, Driscoll, TR, Ebrahimi, H, Eftekharzadeh, S, El Tantawi, M, El-Abid, H, Elbarazi, I, Elhabashy, HR, Elhadi, M, El-Jaafary, SI, Eshrati, B, Eskandarieh, S, Esmaeilzadeh, F, Etemadi, A, Ezzikouri, S, Faisaluddin, M, Faraon, EJA, Fares, J, Farzadfar, F, Feroze, AH, Ferrero, S, Ferro Desideri, L, Filip, I, Fischer, F, Fisher, JL, Foroutan, M, Fukumoto, T, Gaal, PA, Gad, MM, Gadanya, MA, Gallus, S, Gaspar Fonseca, M, Getachew Obsa, A, Ghafourifard, M, Ghashghaee, A, Ghith, N, Gholamalizadeh, M, Gilani, SA, Ginindza, TG, Gizaw, ATT, Glasbey, JC, Golechha, M, Goleij, P, Gomez, RS, Gopalani, SV, Gorini, G, Goudarzi, H, Grosso, G, Gubari, MIM, Guerra, MR, Guha, A, Gunasekera, DS, Gupta, B, Gupta, VB, Gupta, VK, Gutiérrez, RA, Hafezi-Nejad, N, Haider, MR, Haj-Mirzaian, A, Halwani, R, Hamadeh, RR, Hameed, S, Hamidi, S, Hanif, A, Haque, S, Harlianto, NI, Haro, JM, Hasaballah, AI, Hassanipour, S, Hay, RJ, Hay, SI, Hayat, K, Heidari, G, Heidari, M, Herrera-Serna, BY, Herteliu, C, Hezam, K, Holla, R, Hossain, MM, Hossain, MBH, Hosseini, M-S, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Hsairi, M, Huang, J, Hugo, FN, Hussain, R, Hussein, NR, Hwang, B-F, Iavicoli, I, Ibitoye, SE, Ida, F, Ikuta, KS, Ilesanmi, OS, Ilic, IM, Ilic, MD, Irham, LM, Islam, JY, Islam, RM, Islam, SMS, Ismail, NE, Isola, G, Iwagami, M, Jacob, L, Jain, V, Jakovljevic, MB, Javaheri, T, Jayaram, S, Jazayeri, SB, Jha, RP, Jonas, JB, Joo, T, Joseph, N, Joukar, F, Jürisson, M, Kabir, A, Kahrizi, D, Kalankesh, LR, Kalhor, R, Kaliyadan, F, Kalkonde, Y, Kamath, A, Kameran Al-Salihi, N, Kandel, H, Kapoor, N, Karch, A, Kasa, AS, Katikireddi, SV, Kauppila, JH, Kavetskyy, T, Kebede, SA, Keshavarz, P, Keykhaei, M, Khader, YS, Khalilov, R, Khan, G, Khan, M, Khan, MN, Khan, MAB, Khang, Y-H, Khater, AM, Khayamzadeh, M, Kim, GR, Kim, YJ, Kisa, A, Kisa, S, Kissimova-Skarbek, K, Kopec, JA, Koteeswaran, R, Koul, PA, Koulmane Laxminarayana, SL, Koyanagi, A, Kucuk Bicer, B, Kugbey, N, Kumar, GA, Kumar, N, Kurmi, OP, Kutluk, T, La Vecchia, C, Lami, FH, Landires, I, Lauriola, P, Lee, S-W, Lee, SWH, Lee, W-C, Lee, YH, Leigh, J, Leong, E, Li, J, Li, M-C, Liu, X, Loureiro, JA, Lunevicius, R, Magdy Abd El Razek, M, Majeed, A, Makki, A, Male, S, Malik, AA, Mansournia, MA, Martini, S, Masoumi, SZ, Mathur, P, McKee, M, Mehrotra, R, Mendoza, W, Menezes, RG, Mengesha, EW, Mesregah, MK, Mestrovic, T, Miao Jonasson, J, Miazgowski, B, Miazgowski, T, Michalek, IM, Miller, TR, Mirzaei, H, Mirzaei, HR, Misra, S, Mithra, P, Moghadaszadeh, M, Mohammad, KA, Mohammad, Y, Mohammadi, M, Mohammadi, SM, Mohammadian-Hafshejani, A, Mohammed, S, Moka, N, Mokdad, AH, Molokhia, M, Monasta, L, Moni, MA, Moosavi, MA, Moradi, Y, Moraga, P, Morgado-da-Costa, J, Morrison, SD, Mosapour, A, Mubarik, S, Mwanri, L, Nagarajan, AJ, Nagaraju, SP, Nagata, C, Naimzada, MD, Nangia, V, Naqvi, AA, Narasimha Swamy, S, Ndejjo, R, Nduaguba, SO, Negoi, I, Negru, SM, Neupane Kandel, S, Nguyen, CT, Nguyen, HLT, Niazi, RK, Nnaji, CA, Noor, NM, Nuñez-Samudio, V, Nzoputam, CI, Oancea, B, Ochir, C, Odukoya, OO, Ogbo, FA, Olagunju, AT, Olakunde, BO, Omar, E, Omar Bali, A, Omonisi, AEE, Ong, S, Onwujekwe, OE, Orru, H, Ortega-Altamirano, DV, Otstavnov, N, Otstavnov, SS, Owolabi, MO, P A, M, Padubidri, JR, Pakshir, K, Pana, A, Panagiotakos, D, Panda-Jonas, S, Pardhan, S, Park, E-C, Park, E-K, Pashazadeh Kan, F, Patel, HK, Patel, JR, Pati, S, Pattanshetty, SM, Paudel, U, Pereira, DM, Pereira, RB, Perianayagam, A, Pillay, JD, Pirouzpanah, S, Pishgar, F, Podder, I, Postma, MJ, Pourjafar, H, Prashant, A, Preotescu, L, Rabiee, M, Rabiee, N, Radfar, A, Radhakrishnan, RA, Radhakrishnan, V, Rafiee, A, Rahim, F, Rahimzadeh, S, Rahman, M, Rahman, MA, Rahmani, AM, Rajai, N, Rajesh, A, Rakovac, I, Ram, P, Ramezanzadeh, K, Ranabhat, K, Ranasinghe, P, Rao, CR, Rao, SJ, Rawassizadeh, R, Razeghinia, MS, Renzaho, AMN, Rezaei, N, Rezapour, A, Roberts, TJ, Rodriguez, JAB, Rohloff, P, Romoli, M, Ronfani, L, Roshandel, G, Rwegerera, GM, S, M, Sabour, S, Saddik, B, Saeed, U, Sahebkar, A, Sahoo, H, Salehi, S, Salem, MR, Salimzadeh, H, Samaei, M, Samy, AM, Sanabria, J, Sankararaman, S, Santric-Milicevic, MM, Sardiwalla, Y, Sarveazad, A, Sathian, B, Sawhney, M, Saylan, M, Schneider, IJC, Sekerija, M, Seylani, A, Shafaat, O, Shaghaghi, Z, Shaikh, MA, Shamsoddin, E, Shannawaz, M, Sharma, R, Sheikh, A, Sheikhbahaei, S, Shetty, A, Shetty, JK, Shetty, PH, Shibuya, K, Shirkoohi, R, Shivakumar, KM, Shivarov, V, Siabani, S, Siddappa Malleshappa, SK, Silva, DAS, Singh, JA, Sintayehu, Y, Skryabin, VY, Skryabina, AA, Soeberg, MJ, Sofi-Mahmudi, A, Sotoudeh, H, Steiropoulos, P, Straif, K, Subedi, R, Sufiyan, MB, Sultan, I, Sultana, S, Sur, D, Szerencsés, V, Szócska, M, Tabarés-Seisdedos, R, Tabuchi, T, Tadbiri, H, Taherkhani, A, Takahashi, K, Talaat, IM, Tan, K-K, Tat, VY, Tedla, BAA, Tefera, YG, Tehrani-Banihashemi, A, Temsah, M-H, Tesfay, FH, Tessema, GA, Thapar, R, Thavamani, A, Thoguluva Chandrasekar, V, Thomas, N, Tohidinik, HR, Touvier, M, Tovani-Palone, MR, Traini, E, Tran, BX, Tran, KB, Tran, MTN, Tripathy, JP, Tusa, BS, Ullah, I, Ullah, S, Umapathi, KK, Unnikrishnan, B, Upadhyay, E, Vacante, M, Vaezi, M, Valadan Tahbaz, S, Velazquez, DZ, Veroux, M, Violante, FS, Vlassov, V, Vo, B, Volovici, V, Vu, GT, Waheed, Y, Wamai, RG, Ward, P, Wen, YF, Westerman, R, Winkler, AS, Yadav, L, Yahyazadeh Jabbari, SH, Yang, L, Yaya, S, Yazie, TSY, Yeshaw, Y, Yonemoto, N, Younis, MZ, Yousefi, Z, Yu, C, Yuce, D, Yunusa, I, Zadnik, V, Zare, F, Zastrozhin, MS, Zastrozhina, A, Zhang, J, Zhong, C, Zhou, L, Zhu, C, Ziapour, A, Zimmermann, IR, Fitzmaurice, C, Murray, CJL, Force, LM, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Kocarnik, J, Compton, K, Dean, F, Fu, W, Gaw, B, Harvey, J, Henrikson, H, Lu, D, Pennini, A, Xu, R, Ababneh, E, Abbasi-Kangevari, M, Abbastabar, H, Abd-Elsalam, S, Abdoli, A, Abedi, A, Abidi, H, Abolhassani, H, Adedeji, I, Adnani, Q, Advani, S, Afzal, M, Aghaali, M, Ahinkorah, B, Ahmad, S, Ahmad, T, Ahmadi, A, Ahmadi, S, Ahmed Rashid, T, Ahmed Salih, Y, Akalu, G, Aklilu, A, Akram, T, Akunna, C, Al Hamad, H, Alahdab, F, Al-Aly, Z, Ali, S, Alimohamadi, Y, Alipour, V, Aljunid, S, Alkhayyat, M, Almasi-Hashiani, A, Almasri, N, Al-Maweri, S, Almustanyir, S, Alonso, N, Alvis-Guzman, N, Amu, H, Anbesu, E, Ancuceanu, R, Ansari, F, Ansari-Moghaddam, A, Antwi, M, Anvari, D, Anyasodor, A, Aqeel, M, Arabloo, J, Arab-Zozani, M, Aremu, O, Ariffin, H, Aripov, T, Arshad, M, Artaman, A, Arulappan, J, Asemi, Z, Asghari Jafarabadi, M, Ashraf, T, Atorkey, P, Aujayeb, A, Ausloos, M, Awedew, A, Ayala Quintanilla, B, Ayenew, T, Azab, M, Azadnajafabad, S, Azari Jafari, A, Azarian, G, Azzam, A, Badiye, A, Bahadory, S, Baig, A, Baker, J, Balakrishnan, S, Banach, M, Barnighausen, T, Barone-Adesi, F, Barra, F, Barrow, A, Behzadifar, M, Belgaumi, U, Bezabhe, W, Bezabih, Y, Bhagat, D, Bhagavathula, A, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhattacharyya, K, Bhojaraja, V, Bibi, S, Bijani, A, Biondi, A, Bisignano, C, Bjorge, T, Bleyer, A, Blyuss, O, Bolarinwa, O, Bolla, S, Braithwaite, D, Brar, A, Brenner, H, Bustamante-Teixeira, M, Butt, N, Butt, Z, Caetano Dos Santos, F, Cao, Y, Carreras, G, Catala-Lopez, F, Cembranel, F, Cerin, E, Cernigliaro, A, Chakinala, R, Chattu, S, Chattu, V, Chaturvedi, P, Chimed-Ochir, O, Cho, D, Christopher, D, Chu, D, Chung, M, Conde, J, Cortes, S, Cortesi, P, Costa, V, Cunha, A, Dadras, O, Dagnew, A, Dahlawi, S, Dai, X, Dandona, L, Dandona, R, Darwesh, A, Das Neves, J, De La Hoz, F, Demis, A, Denova-Gutierrez, E, Dhamnetiya, D, Dhimal, M, Dianatinasab, M, Diaz, D, Djalalinia, S, Do, H, Doaei, S, Dorostkar, F, Dos Santos Figueiredo, F, Driscoll, T, Ebrahimi, H, Eftekharzadeh, S, El Tantawi, M, El-Abid, H, Elbarazi, I, Elhabashy, H, Elhadi, M, El-Jaafary, S, Eshrati, B, Eskandarieh, S, Esmaeilzadeh, F, Etemadi, A, Ezzikouri, S, Faisaluddin, M, Faraon, E, Fares, J, Farzadfar, F, Feroze, A, Ferrero, S, Ferro Desideri, L, Filip, I, Fischer, F, Fisher, J, Foroutan, M, Fukumoto, T, Gaal, P, Gad, M, Gadanya, M, Gallus, S, Gaspar Fonseca, M, Getachew Obsa, A, Ghafourifard, M, Ghashghaee, A, Ghith, N, Gholamalizadeh, M, Gilani, S, Ginindza, T, Gizaw, A, Glasbey, J, Golechha, M, Goleij, P, Gomez, R, Gopalani, S, Gorini, G, Goudarzi, H, Grosso, G, Gubari, M, Guerra, M, Guha, A, Gunasekera, D, Gupta, B, Gupta, V, Gutierrez, R, Hafezi-Nejad, N, Haider, M, Haj-Mirzaian, A, Halwani, R, Hamadeh, R, Hameed, S, Hamidi, S, Hanif, A, Haque, S, Harlianto, N, Haro, J, Hasaballah, A, Hassanipour, S, Hay, R, Hay, S, Hayat, K, Heidari, G, Heidari, M, Herrera-Serna, B, Herteliu, C, Hezam, K, Holla, R, Hossain, M, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Hsairi, M, Huang, J, Hugo, F, Hussain, R, Hussein, N, Hwang, B, Iavicoli, I, Ibitoye, S, Ida, F, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Irham, L, Islam, J, Islam, R, Islam, S, Ismail, N, Isola, G, Iwagami, M, Jacob, L, Jain, V, Jakovljevic, M, Javaheri, T, Jayaram, S, Jazayeri, S, Jha, R, Jonas, J, Joo, T, Joseph, N, Joukar, F, Jurisson, M, Kabir, A, Kahrizi, D, Kalankesh, L, Kalhor, R, Kaliyadan, F, Kalkonde, Y, Kamath, A, Kameran Al-Salihi, N, Kandel, H, Kapoor, N, Karch, A, Kasa, A, Katikireddi, S, Kauppila, J, Kavetskyy, T, Kebede, S, Keshavarz, P, Keykhaei, M, Khader, Y, Khalilov, R, Khan, G, Khan, M, Khang, Y, Khater, A, Khayamzadeh, M, Kim, G, Kim, Y, Kisa, A, Kisa, S, Kissimova-Skarbek, K, Kopec, J, Koteeswaran, R, Koul, P, Koulmane Laxminarayana, S, Koyanagi, A, Kucuk Bicer, B, Kugbey, N, Kumar, G, Kumar, N, Kurmi, O, Kutluk, T, La Vecchia, C, Lami, F, Landires, I, Lauriola, P, Lee, S, Lee, W, Lee, Y, Leigh, J, Leong, E, Li, J, Li, M, Liu, X, Loureiro, J, Lunevicius, R, Magdy Abd El Razek, M, Majeed, A, Makki, A, Male, S, Malik, A, Mansournia, M, Martini, S, Masoumi, S, Mathur, P, Mckee, M, Mehrotra, R, Mendoza, W, Menezes, R, Mengesha, E, Mesregah, M, Mestrovic, T, Miao Jonasson, J, Miazgowski, B, Miazgowski, T, Michalek, I, Miller, T, Mirzaei, H, Misra, S, Mithra, P, Moghadaszadeh, M, Mohammad, K, Mohammad, Y, Mohammadi, M, Mohammadi, S, Mohammadian-Hafshejani, A, Mohammed, S, Moka, N, Mokdad, A, Molokhia, M, Monasta, L, Moni, M, Moosavi, M, Moradi, Y, Moraga, P, Morgado-Da-Costa, J, Morrison, S, Mosapour, A, Mubarik, S, Mwanri, L, Nagarajan, A, Nagaraju, S, Nagata, C, Naimzada, M, Nangia, V, Naqvi, A, Narasimha Swamy, S, Ndejjo, R, Nduaguba, S, Negoi, I, Negru, S, Neupane Kandel, S, Nguyen, C, Nguyen, H, Niazi, R, Nnaji, C, Noor, N, Nunez-Samudio, V, Nzoputam, C, Oancea, B, Ochir, C, Odukoya, O, Ogbo, F, Olagunju, A, Olakunde, B, Omar, E, Omar Bali, A, Omonisi, A, Ong, S, Onwujekwe, O, Orru, H, Ortega-Altamirano, D, Otstavnov, N, Otstavnov, S, Owolabi, M, P A, M, Padubidri, J, Pakshir, K, Pana, A, Panagiotakos, D, Panda-Jonas, S, Pardhan, S, Park, E, Pashazadeh Kan, F, Patel, H, Patel, J, Pati, S, Pattanshetty, S, Paudel, U, Pereira, D, Pereira, R, Perianayagam, A, Pillay, J, Pirouzpanah, S, Pishgar, F, Podder, I, Postma, M, Pourjafar, H, Prashant, A, Preotescu, L, Rabiee, M, Rabiee, N, Radfar, A, Radhakrishnan, R, Radhakrishnan, V, Rafiee, A, Rahim, F, Rahimzadeh, S, Rahman, M, Rahmani, A, Rajai, N, Rajesh, A, Rakovac, I, Ram, P, Ramezanzadeh, K, Ranabhat, K, Ranasinghe, P, Rao, C, Rao, S, Rawassizadeh, R, Razeghinia, M, Renzaho, A, Rezaei, N, Rezapour, A, Roberts, T, Rodriguez, J, Rohloff, P, Romoli, M, Ronfani, L, Roshandel, G, Rwegerera, G, Manjula, S, Sabour, S, Saddik, B, Saeed, U, Sahebkar, A, Sahoo, H, Salehi, S, Salem, M, Salimzadeh, H, Samaei, M, Samy, A, Sanabria, J, Sankararaman, S, Santric-Milicevic, M, Sardiwalla, Y, Sarveazad, A, Sathian, B, Sawhney, M, Saylan, M, Schneider, I, Sekerija, M, Seylani, A, Shafaat, O, Shaghaghi, Z, Shaikh, M, Shamsoddin, E, Shannawaz, M, Sharma, R, Sheikh, A, Sheikhbahaei, S, Shetty, A, Shetty, J, Shetty, P, Shibuya, K, Shirkoohi, R, Shivakumar, K, Shivarov, V, Siabani, S, Siddappa Malleshappa, S, Silva, D, Singh, J, Sintayehu, Y, Skryabin, V, Skryabina, A, Soeberg, M, Sofi-Mahmudi, A, Sotoudeh, H, Steiropoulos, P, Straif, K, Subedi, R, Sufiyan, M, Sultan, I, Sultana, S, Sur, D, Szerencses, V, Szocska, M, Tabares-Seisdedos, R, Tabuchi, T, Tadbiri, H, Taherkhani, A, Takahashi, K, Talaat, I, Tan, K, Tat, V, Tedla, B, Tefera, Y, Tehrani-Banihashemi, A, Temsah, M, Tesfay, F, Tessema, G, Thapar, R, Thavamani, A, Thoguluva Chandrasekar, V, Thomas, N, Tohidinik, H, Touvier, M, Tovani-Palone, M, Traini, E, Tran, B, Tran, K, Tran, M, Tripathy, J, Tusa, B, Ullah, I, Ullah, S, Umapathi, K, Unnikrishnan, B, Upadhyay, E, Vacante, M, Vaezi, M, Valadan Tahbaz, S, Velazquez, D, Veroux, M, Violante, F, Vlassov, V, Vo, B, Volovici, V, Vu, G, Waheed, Y, Wamai, R, Ward, P, Wen, Y, Westerman, R, Winkler, A, Yadav, L, Yahyazadeh Jabbari, S, Yang, L, Yaya, S, Yazie, T, Yeshaw, Y, Yonemoto, N, Younis, M, Yousefi, Z, Yu, C, Yuce, D, Yunusa, I, Zadnik, V, Zare, F, Zastrozhin, M, Zastrozhina, A, Zhang, J, Zhong, C, Zhou, L, Zhu, C, Ziapour, A, Zimmermann, I, Fitzmaurice, C, Murray, C, Force, L, Kocarnik J.M., Compton K., Dean F.E., Fu W., Gaw B.L., Harvey J.D., Henrikson H.J., Lu D., Pennini A., Xu R., Ababneh E., Abbasi-Kangevari M., Abbastabar H., Abd-Elsalam S.M., Abdoli A., Abedi A., Abidi H., Abolhassani H., Adedeji I.A., Adnani Q.E.S., Advani S.M., Afzal M.S., Aghaali M., Ahinkorah B.O., Ahmad S., Ahmad T., Ahmadi A., Ahmadi S., Ahmed Rashid T., Ahmed Salih Y., Akalu G.T., Aklilu A., Akram T., Akunna C.J., Al Hamad H., Alahdab F., Al-Aly Z., Ali S., Alimohamadi Y., Alipour V., Aljunid S.M., Alkhayyat M., Almasi-Hashiani A., Almasri N.A., Al-Maweri S.A.A., Almustanyir S., Alonso N., Alvis-Guzman N., Amu H., Anbesu E.W., Ancuceanu R., Ansari F., Ansari-Moghaddam A., Antwi M.H., Anvari D., Anyasodor A.E., Aqeel M., Arabloo J., Arab-Zozani M., Aremu O., Ariffin H., Aripov T., Arshad M., Artaman A., Arulappan J., Asemi Z., Asghari Jafarabadi M., Ashraf T., Atorkey P., Aujayeb A., Ausloos M., Awedew A.F., Ayala Quintanilla B.P., Ayenew T., Azab M.A., Azadnajafabad S., Azari Jafari A., Azarian G., Azzam A.Y., Badiye A.D., Bahadory S., Baig A.A., Baker J.L., Balakrishnan S., Banach M., Barnighausen T.W., Barone-Adesi F., Barra F., Barrow A., Behzadifar M., Belgaumi U.I., Bezabhe W.M.M., Bezabih Y.M., Bhagat D.S., Bhagavathula A.S., Bhardwaj N., Bhardwaj P., Bhaskar S., Bhattacharyya K., Bhojaraja V.S., Bibi S., Bijani A., Biondi A., Bisignano C., Bjorge T., Bleyer A., Blyuss O., Bolarinwa O.A., Bolla S.R., Braithwaite D., Brar A., Brenner H., Bustamante-Teixeira M.T., Butt N.S., Butt Z.A., Caetano dos Santos F.L., Cao Y., Carreras G., Catala-Lopez F., Cembranel F., Cerin E., Cernigliaro A., Chakinala R.C., Chattu S.K., Chattu V.K., Chaturvedi P., Chimed-Ochir O., Cho D.Y., Christopher D.J., Chu D.-T., Chung M.T., Conde J., Cortes S., Cortesi P.A., Costa V.M., Cunha A.R., Dadras O., Dagnew A.B., Dahlawi S.M.A., Dai X., Dandona L., Dandona R., Darwesh A.M., das Neves J., De la Hoz F.P., Demis A.B., Denova-Gutierrez E., Dhamnetiya D., Dhimal M.L., Dhimal M., Dianatinasab M., Diaz D., Djalalinia S., Do H.P., Doaei S., Dorostkar F., dos Santos Figueiredo F.W., Driscoll T.R., Ebrahimi H., Eftekharzadeh S., El Tantawi M., El-Abid H., Elbarazi I., Elhabashy H.R., Elhadi M., El-Jaafary S.I., Eshrati B., Eskandarieh S., Esmaeilzadeh F., Etemadi A., Ezzikouri S., Faisaluddin M., Faraon E.J.A., Fares J., Farzadfar F., Feroze A.H., Ferrero S., Ferro Desideri L., Filip I., Fischer F., Fisher J.L., Foroutan M., Fukumoto T., Gaal P.A., Gad M.M., Gadanya M.A., Gallus S., Gaspar Fonseca M., Getachew Obsa A., Ghafourifard M., Ghashghaee A., Ghith N., Gholamalizadeh M., Gilani S.A., Ginindza T.G., Gizaw A.T.T., Glasbey J.C., Golechha M., Goleij P., Gomez R.S., Gopalani S.V., Gorini G., Goudarzi H., Grosso G., Gubari M.I.M., Guerra M.R., Guha A., Gunasekera D.S., Gupta B., Gupta V.B., Gupta V.K., Gutierrez R.A., Hafezi-Nejad N., Haider M.R., Haj-Mirzaian A., Halwani R., Hamadeh R.R., Hameed S., Hamidi S., Hanif A., Haque S., Harlianto N.I., Haro J.M., Hasaballah A.I., Hassanipour S., Hay R.J., Hay S.I., Hayat K., Heidari G., Heidari M., Herrera-Serna B.Y., Herteliu C., Hezam K., Holla R., Hossain M.M., Hossain M.B.H., Hosseini M.-S., Hosseini M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Househ M., Hsairi M., Huang J., Hugo F.N., Hussain R., Hussein N.R., Hwang B.-F., Iavicoli I., Ibitoye S.E., Ida F., Ikuta K.S., Ilesanmi O.S., Ilic I.M., Ilic M.D., Irham L.M., Islam J.Y., Islam R.M., Islam S.M.S., Ismail N.E., Isola G., Iwagami M., Jacob L., Jain V., Jakovljevic M.B., Javaheri T., Jayaram S., Jazayeri S.B., Jha R.P., Jonas J.B., Joo T., Joseph N., Joukar F., Jurisson M., Kabir A., Kahrizi D., Kalankesh L.R., Kalhor R., Kaliyadan F., Kalkonde Y., Kamath A., Kameran Al-Salihi N., Kandel H., Kapoor N., Karch A., Kasa A.S., Katikireddi S.V., Kauppila J.H., Kavetskyy T., Kebede S.A., Keshavarz P., Keykhaei M., Khader Y.S., Khalilov R., Khan G., Khan M., Khan M.N., Khan M.A.B., Khang Y.-H., Khater A.M., Khayamzadeh M., Kim G.R., Kim Y.J., Kisa A., Kisa S., Kissimova-Skarbek K., Kopec J.A., Koteeswaran R., Koul P.A., Koulmane Laxminarayana S.L., Koyanagi A., Kucuk Bicer B., Kugbey N., Kumar G.A., Kumar N., Kurmi O.P., Kutluk T., La Vecchia C., Lami F.H., Landires I., Lauriola P., Lee S.-W., Lee S.W.H., Lee W.-C., Lee Y.H., Leigh J., Leong E., Li J., Li M.-C., Liu X., Loureiro J.A., Lunevicius R., Magdy Abd El Razek M., Majeed A., Makki A., Male S., Malik A.A., Mansournia M.A., Martini S., Masoumi S.Z., Mathur P., McKee M., Mehrotra R., Mendoza W., Menezes R.G., Mengesha E.W., Mesregah M.K., Mestrovic T., Miao Jonasson J., Miazgowski B., Miazgowski T., Michalek I.M., Miller T.R., Mirzaei H., Mirzaei H.R., Misra S., Mithra P., Moghadaszadeh M., Mohammad K.A., Mohammad Y., Mohammadi M., Mohammadi S.M., Mohammadian-Hafshejani A., Mohammed S., Moka N., Mokdad A.H., Molokhia M., Monasta L., Moni M.A., Moosavi M.A., Moradi Y., Moraga P., Morgado-Da-Costa J., Morrison S.D., Mosapour A., Mubarik S., Mwanri L., Nagarajan A.J., Nagaraju S.P., Nagata C., Naimzada M.D., Nangia V., Naqvi A.A., Narasimha Swamy S., Ndejjo R., Nduaguba S.O., Negoi I., Negru S.M., Neupane Kandel S., Nguyen C.T., Nguyen H.L.T., Niazi R.K., Nnaji C.A., Noor N.M., Nunez-Samudio V., Nzoputam C.I., Oancea B., Ochir C., Odukoya O.O., Ogbo F.A., Olagunju A.T., Olakunde B.O., Omar E., Omar Bali A.O., Omonisi A.E.E., Ong S., Onwujekwe O.E., Orru H., Ortega-Altamirano D.V., Otstavnov N., Otstavnov S.S., Owolabi M.O., P A M., Padubidri J.R., Pakshir K., Pana A., Panagiotakos D., Panda-Jonas S., Pardhan S., Park E.-C., Park E.-K., Pashazadeh Kan F., Patel H.K., Patel J.R., Pati S., Pattanshetty S.M., Paudel U., Pereira D.M., Pereira R.B., Perianayagam A., Pillay J.D., Pirouzpanah S., Pishgar F., Podder I., Postma M.J., Pourjafar H., Prashant A., Preotescu L., Rabiee M., Rabiee N., Radfar A., Radhakrishnan R.A., Radhakrishnan V., Rafiee A., Rahim F., Rahimzadeh S., Rahman M., Rahman M.A., Rahmani A.M., Rajai N., Rajesh A., Rakovac I., Ram P., Ramezanzadeh K., Ranabhat K., Ranasinghe P., Rao C.R., Rao S.J., Rawassizadeh R., Razeghinia M.S., Renzaho A.M.N., Rezaei N., Rezapour A., Roberts T.J., Rodriguez J.A.B., Rohloff P., Romoli M., Ronfani L., Roshandel G., Rwegerera G.M., Manjula S., Sabour S., Saddik B., Saeed U., Sahebkar A., Sahoo H., Salehi S., Salem M.R., Salimzadeh H., Samaei M., Samy A.M., Sanabria J., Sankararaman S., Santric-Milicevic M.M., Sardiwalla Y., Sarveazad A., Sathian B., Sawhney M., Saylan M., Schneider I.J.J., Sekerija M., Seylani A., Shafaat O., Shaghaghi Z., Shaikh M.A., Shamsoddin E., Shannawaz M., Sharma R., Sheikh A., Sheikhbahaei S., Shetty A., Shetty J.K., Shetty P.H., Shibuya K., Shirkoohi R., Shivakumar K.M., Shivarov V., Siabani S., Siddappa Malleshappa S.K., Silva D.A.S., Singh J.A., Sintayehu Y., Skryabin V.Y., Skryabina A.A., Soeberg M.J., Sofi-Mahmudi A., Sotoudeh H., Steiropoulos P., Straif K., Subedi R., Sufiyan M.B., Sultan I., Sultana S., Sur D., Szerencses V., Szocska M., Tabares-Seisdedos R., Tabuchi T., Tadbiri H., Taherkhani A., Takahashi K., Talaat I.M., Tan K.-K., Tat V.Y., Tedla B.A.A., Tefera Y.G., Tehrani-Banihashemi A., Temsah M., Tesfay F.H., Tessema G.A., Thapar R., Thavamani A., Thoguluva Chandrasekar V., Thomas N., Tohidinik H.R., Touvier M., Tovani-Palone M.R., Traini E., Tran B.X., Tran K.B., Tran M.T.N., Tripathy J.P., Tusa B.S., Ullah I., Ullah S., Umapathi K.K., Unnikrishnan B., Upadhyay E., Vacante M., Vaezi M., Valadan Tahbaz S., Velazquez D.Z., Veroux M., Violante F.S., Vlassov V., Vo B., Volovici V., Vu G.T., Waheed Y., Wamai R.G., Ward P., Wen Y.F., Westerman R., Winkler A.S., Yadav L., Yahyazadeh Jabbari S.H., Yang L., Yaya S., Yazie T.S.Y., Yeshaw Y., Yonemoto N., Younis M.Z., Yousefi Z., Yu C., Yuce D., Yunusa I., Zadnik V., Zare F., Zastrozhin M.S., Zastrozhina A., Zhang J., Zhong C., Zhou L., Zhu C., Ziapour A., Zimmermann I.R., Fitzmaurice C., Murray C.J.L., Force L.M., Bill & Melinda Gates Foundation, American Lebanese Syrian Associated Charities, Kuwait University (Kuwait), National University of Malaysia (Malasia), Alexander von Humboldt Foundation, Federal Ministry of Education & Research (Alemania), NIH - National Cancer Institute (NCI) (Estados Unidos), Unión Europea. Comisión Europea. European Research Council (ERC), Unión Europea. Comisión Europea. H2020, Novo Nordisk Foundation, National Health and Medical Research Council (Australia), Jazan University (Arabia Saudí), Romanian National Authority for Scientific Research and Innovation, Ministry of Education (Brasil), National Heart Foundation of Australia, Ministry of Education, Science and Technological Development (Serbia), NHS - Research Scotland (Reino Unido), Medical Research Council (Reino Unido), Scottish Government (Reino Unido), Jatiya Kabi Kazi Nazrul Islam University (Bangladesh), Xiamen University (Malasia), Manipal Academy of Higher Education (India), Sistema Nacional de Investigación (Panamá), Secretaría Nacional de Ciencia, Tecnología e Innovación (Panamá), King College London, National Health Service (Reino Unido), Government of the Russian Federation, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil), National Council for Scientific and Technological Development (Brasil), Cancer Prevention and Research Institute of Texas (Estados Unidos), Fundação para a Ciência e Tecnologia (Portugal), Neurosurgery, Kocarnik, J. M., Compton, K., Dean, F. E., Fu, W., Gaw, B. L., Harvey, J. D., Henrikson, H. J., Lu, D., Pennini, A., Xu, R., Ababneh, E., Abbasi-Kangevari, M., Abbastabar, H., Abd-Elsalam, S. M., Abdoli, A., Abedi, A., Abidi, H., Abolhassani, H., Adedeji, I. A., Adnani, Q. E. S., Advani, S. M., Afzal, M. S., Aghaali, M., Ahinkorah, B. O., Ahmad, S., Ahmad, T., Ahmadi, A., Ahmadi, S., Ahmed Rashid, T., Ahmed Salih, Y., Akalu, G. T., Aklilu, A., Akram, T., Akunna, C. J., Al Hamad, H., Alahdab, F., Al-Aly, Z., Ali, S., Alimohamadi, Y., Alipour, V., Aljunid, S. M., Alkhayyat, M., Almasi-Hashiani, A., Almasri, N. A., Al-Maweri, S. A. A., Almustanyir, S., Alonso, N., Alvis-Guzman, N., Amu, H., Anbesu, E. W., Ancuceanu, R., Ansari, F., Ansari-Moghaddam, A., Antwi, M. H., Anvari, D., Anyasodor, A. E., Aqeel, M., Arabloo, J., Arab-Zozani, M., Aremu, O., Ariffin, H., Aripov, T., Arshad, M., Artaman, A., Arulappan, J., Asemi, Z., Asghari Jafarabadi, M., Ashraf, T., Atorkey, P., Aujayeb, A., Ausloos, M., Awedew, A. F., Ayala Quintanilla, B. P., Ayenew, T., Azab, M. A., Azadnajafabad, S., Azari Jafari, A., Azarian, G., Azzam, A. Y., Badiye, A. D., Bahadory, S., Baig, A. A., Baker, J. L., Balakrishnan, S., Banach, M., Barnighausen, T. W., Barone-Adesi, F., Barra, F., Barrow, A., Behzadifar, M., Belgaumi, U. I., Bezabhe, W. M. M., Bezabih, Y. M., Bhagat, D. S., Bhagavathula, A. S., Bhardwaj, N., Bhardwaj, P., Bhaskar, S., Bhattacharyya, K., Bhojaraja, V. S., Bibi, S., Bijani, A., Biondi, A., Bisignano, C., Bjorge, T., Bleyer, A., Blyuss, O., Bolarinwa, O. A., Bolla, S. R., Braithwaite, D., Brar, A., Brenner, H., Bustamante-Teixeira, M. T., Butt, N. S., Butt, Z. A., Caetano Dos Santos, F. L., Cao, Y., Carreras, G., Catala-Lopez, F., Cembranel, F., Cerin, E., Cernigliaro, A., Chakinala, R. C., Chattu, S. K., Chattu, V. K., Chaturvedi, P., Chimed-Ochir, O., Cho, D. Y., Christopher, D. J., Chu, D. -T., Chung, M. T., Conde, J., Cortes, S., Cortesi, P. A., Costa, V. M., Cunha, A. R., Dadras, O., Dagnew, A. B., Dahlawi, S. M. A., Dai, X., Dandona, L., Dandona, R., Darwesh, A. M., Das Neves, J., De La Hoz, F. P., Demis, A. B., Denova-Gutierrez, E., Dhamnetiya, D., Dhimal, M. L., Dhimal, M., Dianatinasab, M., Diaz, D., Djalalinia, S., Do, H. P., Doaei, S., Dorostkar, F., Dos Santos Figueiredo, F. W., Driscoll, T. R., Ebrahimi, H., Eftekharzadeh, S., El Tantawi, M., El-Abid, H., Elbarazi, I., Elhabashy, H. R., Elhadi, M., El-Jaafary, S. I., Eshrati, B., Eskandarieh, S., Esmaeilzadeh, F., Etemadi, A., Ezzikouri, S., Faisaluddin, M., Faraon, E. J. A., Fares, J., Farzadfar, F., Feroze, A. H., Ferrero, S., Ferro Desideri, L., Filip, I., Fischer, F., Fisher, J. L., Foroutan, M., Fukumoto, T., Gaal, P. A., Gad, M. M., Gadanya, M. A., Gallus, S., Gaspar Fonseca, M., Getachew Obsa, A., Ghafourifard, M., Ghashghaee, A., Ghith, N., Gholamalizadeh, M., Gilani, S. A., Ginindza, T. G., Gizaw, A. T. T., Glasbey, J. C., Golechha, M., Goleij, P., Gomez, R. S., Gopalani, S. V., Gorini, G., Goudarzi, H., Grosso, G., Gubari, M. I. M., Guerra, M. R., Guha, A., Gunasekera, D. S., Gupta, B., Gupta, V. B., Gupta, V. K., Gutierrez, R. A., Hafezi-Nejad, N., Haider, M. R., Haj-Mirzaian, A., Halwani, R., Hamadeh, R. R., Hameed, S., Hamidi, S., Hanif, A., Haque, S., Harlianto, N. I., Haro, J. M., Hasaballah, A. I., Hassanipour, S., Hay, R. J., Hay, S. I., Hayat, K., Heidari, G., Heidari, M., Herrera-Serna, B. Y., Herteliu, C., Hezam, K., Holla, R., Hossain, M. M., Hossain, M. B. H., Hosseini, M. -S., Hosseini, M., Hosseinzadeh, M., Hostiuc, M., Hostiuc, S., Househ, M., Hsairi, M., Huang, J., Hugo, F. N., Hussain, R., Hussein, N. R., Hwang, B. -F., Iavicoli, I., Ibitoye, S. E., Ida, F., Ikuta, K. S., Ilesanmi, O. S., Ilic, I. M., Ilic, M. D., Irham, L. M., Islam, J. Y., Islam, R. M., Islam, S. M. S., Ismail, N. E., Isola, G., Iwagami, M., Jacob, L., Jain, V., Jakovljevic, M. B., Javaheri, T., Jayaram, S., Jazayeri, S. B., Jha, R. P., Jonas, J. B., Joo, T., Joseph, N., Joukar, F., Jurisson, M., Kabir, A., Kahrizi, D., Kalankesh, L. R., Kalhor, R., Kaliyadan, F., Kalkonde, Y., Kamath, A., Kameran Al-Salihi, N., Kandel, H., Kapoor, N., Karch, A., Kasa, A. S., Katikireddi, S. V., Kauppila, J. H., Kavetskyy, T., Kebede, S. A., Keshavarz, P., Keykhaei, M., Khader, Y. S., Khalilov, R., Khan, G., Khan, M., Khan, M. N., Khan, M. A. B., Khang, Y. -H., Khater, A. M., Khayamzadeh, M., Kim, G. R., Kim, Y. J., Kisa, A., Kisa, S., Kissimova-Skarbek, K., Kopec, J. A., Koteeswaran, R., Koul, P. A., Koulmane Laxminarayana, S. L., Koyanagi, A., Kucuk Bicer, B., Kugbey, N., Kumar, G. A., Kumar, N., Kurmi, O. P., Kutluk, T., La Vecchia, C., Lami, F. H., Landires, I., Lauriola, P., Lee, S. -W., Lee, S. W. H., Lee, W. -C., Lee, Y. H., Leigh, J., Leong, E., Li, J., Li, M. -C., Liu, X., Loureiro, J. A., Lunevicius, R., Magdy Abd El Razek, M., Majeed, A., Makki, A., Male, S., Malik, A. A., Mansournia, M. A., Martini, S., Masoumi, S. Z., Mathur, P., Mckee, M., Mehrotra, R., Mendoza, W., Menezes, R. G., Mengesha, E. W., Mesregah, M. K., Mestrovic, T., Miao Jonasson, J., Miazgowski, B., Miazgowski, T., Michalek, I. M., Miller, T. R., Mirzaei, H., Mirzaei, H. R., Misra, S., Mithra, P., Moghadaszadeh, M., Mohammad, K. A., Mohammad, Y., Mohammadi, M., Mohammadi, S. M., Mohammadian-Hafshejani, A., Mohammed, S., Moka, N., Mokdad, A. H., Molokhia, M., Monasta, L., Moni, M. A., Moosavi, M. A., Moradi, Y., Moraga, P., Morgado-Da-Costa, J., Morrison, S. D., Mosapour, A., Mubarik, S., Mwanri, L., Nagarajan, A. J., Nagaraju, S. P., Nagata, C., Naimzada, M. D., Nangia, V., Naqvi, A. A., Narasimha Swamy, S., Ndejjo, R., Nduaguba, S. O., Negoi, I., Negru, S. M., Neupane Kandel, S., Nguyen, C. T., Nguyen, H. L. T., Niazi, R. K., Nnaji, C. A., Noor, N. M., Nunez-Samudio, V., Nzoputam, C. I., Oancea, B., Ochir, C., Odukoya, O. O., Ogbo, F. A., Olagunju, A. T., Olakunde, B. O., Omar, E., Omar Bali, A., Omonisi, A. E. E., Ong, S., Onwujekwe, O. E., Orru, H., Ortega-Altamirano, D. V., Otstavnov, N., Otstavnov, S. S., Owolabi, M. O., P A, M., Padubidri, J. R., Pakshir, K., Pana, A., Panagiotakos, D., Panda-Jonas, S., Pardhan, S., Park, E. -C., Park, E. -K., Pashazadeh Kan, F., Patel, H. K., Patel, J. R., Pati, S., Pattanshetty, S. M., Paudel, U., Pereira, D. M., Pereira, R. B., Perianayagam, A., Pillay, J. D., Pirouzpanah, S., Pishgar, F., Podder, I., Postma, M. J., Pourjafar, H., Prashant, A., Preotescu, L., Rabiee, M., Rabiee, N., Radfar, A., Radhakrishnan, R. A., Radhakrishnan, V., Rafiee, A., Rahim, F., Rahimzadeh, S., Rahman, M., Rahman, M. A., Rahmani, A. M., Rajai, N., Rajesh, A., Rakovac, I., Ram, P., Ramezanzadeh, K., Ranabhat, K., Ranasinghe, P., Rao, C. R., Rao, S. J., Rawassizadeh, R., Razeghinia, M. S., Renzaho, A. M. N., Rezaei, N., Rezapour, A., Roberts, T. J., Rodriguez, J. A. B., Rohloff, P., Romoli, M., Ronfani, L., Roshandel, G., Rwegerera, G. M., Manjula, S., Sabour, S., Saddik, B., Saeed, U., Sahebkar, A., Sahoo, H., Salehi, S., Salem, M. R., Salimzadeh, H., Samaei, M., Samy, A. M., Sanabria, J., Sankararaman, S., Santric-Milicevic, M. M., Sardiwalla, Y., Sarveazad, A., Sathian, B., Sawhney, M., Saylan, M., Schneider, I. J. C., Sekerija, M., Seylani, A., Shafaat, O., Shaghaghi, Z., Shaikh, M. A., Shamsoddin, E., Shannawaz, M., Sharma, R., Sheikh, A., Sheikhbahaei, S., Shetty, A., Shetty, J. K., Shetty, P. H., Shibuya, K., Shirkoohi, R., Shivakumar, K. M., Shivarov, V., Siabani, S., Siddappa Malleshappa, S. K., Silva, D. A. S., Singh, J. A., Sintayehu, Y., Skryabin, V. Y., Skryabina, A. A., Soeberg, M. J., Sofi-Mahmudi, A., Sotoudeh, H., Steiropoulos, P., Straif, K., Subedi, R., Sufiyan, M. B., Sultan, I., Sultana, S., Sur, D., Szerencses, V., Szocska, M., Tabares-Seisdedos, R., Tabuchi, T., Tadbiri, H., Taherkhani, A., Takahashi, K., Talaat, I. M., Tan, K. -K., Tat, V. Y., Tedla, B. A. A., Tefera, Y. G., Tehrani-Banihashemi, A., Temsah, M. -H., Tesfay, F. H., Tessema, G. A., Thapar, R., Thavamani, A., Thoguluva Chandrasekar, V., Thomas, N., Tohidinik, H. R., Touvier, M., Tovani-Palone, M. R., Traini, E., Tran, B. X., Tran, K. B., Tran, M. T. N., Tripathy, J. P., Tusa, B. S., Ullah, I., Ullah, S., Umapathi, K. K., Unnikrishnan, B., Upadhyay, E., Vacante, M., Vaezi, M., Valadan Tahbaz, S., Velazquez, D. Z., Veroux, M., Violante, F. S., Vlassov, V., Vo, B., Volovici, V., Vu, G. T., Waheed, Y., Wamai, R. G., Ward, P., Wen, Y. F., Westerman, R., Winkler, A. S., Yadav, L., Yahyazadeh Jabbari, S. H., Yang, L., Yaya, S., Yazie, T. S. Y., Yeshaw, Y., Yonemoto, N., Younis, M. Z., Yousefi, Z., Yu, C., Yuce, D., Yunusa, I., Zadnik, V., Zare, F., Zastrozhin, M. S., Zastrozhina, A., Zhang, J., Zhong, C., Zhou, L., Zhu, C., Ziapour, A., Zimmermann, I. R., Fitzmaurice, C., Murray, C. J. L., and Force, L. M.
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Cancer Research ,GBD ,195 COUNTRIES ,Global Health ,1117 Public Health and Health Services ,Global Burden of Disease ,SDG 3 - Good Health and Well-being ,WORLDWIDE ,Risk Factors ,Neoplasms ,SURVEILLANCE ,SUPPORT ,Global Burden of Disease 2019 Cancer Collaboration ,Prevalence ,Online First ,cancer ,Humans ,1112 Oncology and Carcinogenesis ,public health, cancer, burden of diseases ,PROGRESS ,Original Investigation ,Global burden ,Science & Technology ,CHALLENGES ,Research ,Incidence ,Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762 [VDP] ,COVID-19 ,1112 Oncology and Carcinogenesis, 1117 Public Health and Health Services ,Disability-Adjusted Life Years ,mortality ,STATISTICS ,Oncology ,Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 A Systematic Analysis for the Global Burden of Disease Study 2019 ,HEALTH-CARE ,TERRITORIES ,Quality-Adjusted Life Years ,Life Sciences & Biomedicine ,Comments - Abstract
Key Points Question What was the burden of cancer globally and across Sociodemographic Index (SDI) groupings in 2019, and how has incidence, morbidity, and mortality changed since 2010? Findings In this systematic analysis, there were 23.6 million new global cancer cases in 2019 (17.2 million when excluding those with nonmelanoma skin cancer), 10.0 million cancer deaths, and an estimated 250 million disability-adjusted life years estimated to be due to cancer; since 2010, these represent increases of 26.3%, 20.9%, and 16.0%, respectively. Absolute cancer burden increased in all SDI quintiles since 2010, but the largest percentage increases occurred in the low and low-middle SDI quintiles. Meanings The study results suggest that increased cancer prevention and control efforts are needed to equitably address the evolving and increasing burden of cancer across the SDI spectrum., Importance The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. Objective To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. Evidence Review The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). Findings In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. Conclusions and Relevance The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world., The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 examines cancer burden and trends globally for 204 countries and territories and by Socio-demographic Index quintiles from 2010 to 2019.
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- 2022
7. Mobile as a Sensor in Intelligent Transportation System for Street Route
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Dharani, Andhe, primary, Vijaylakshmi, M N, additional, and Narasimha Swamy, S., additional
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- 2018
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8. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
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Brittney S Sheena, Lindsey Hiebert, Hannah Han, Helen Ippolito, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Amir Abdoli, Hiwa Abubaker Ali, Mesafint Molla Adane, Oyelola A Adegboye, Qorinah Estiningtyas Sakilah Adnani, Shailesh M Advani, Muhammad Sohail Afzal, Saira Afzal, Mohamad Aghaie Meybodi, Bahman Ahadinezhad, Bright Opoku Ahinkorah, Sajjad Ahmad, Tauseef Ahmad, Sepideh Ahmadi, Haroon Ahmed, Muktar Beshir Ahmed, Tarik Ahmed Rashid, Gizachew Taddesse Akalu, Addis Aklilu, Tayyaba Akram, Hanadi Al Hamad, Fares Alahdab, Adugnaw Zeleke Alem, Dejene Tsegaye Alem, Fadwa Alhalaiqa Naji Alhalaiqa, Robert Kaba Alhassan, Liaqat Ali, Muhammad Ashar Ali, Yousef Alimohamadi, Vahid Alipour, Motasem Alkhayyat, Sami Almustanyir, Rajaa M Al-Raddadi, Haya Altawalah, Saeed Amini, Hubert Amu, Robert Ancuceanu, Catalina Liliana Andrei, Tudorel Andrei, Amir Anoushiravani, Adnan Ansar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Morteza Arab-Zozani, Ayele Mamo Argaw, Zeleke Gebru Argaw, Muhammad Arshad, Anton A Artamonov, Tahira Ashraf, Daniel Atlaw, Floriane Ausloos, Marcel Ausloos, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Amirhossein Azari Jafari, Ghasem Azarian, Sayna Bagheri, Saeed Bahadory, Atif Amin Baig, Maciej Banach, Nastaran Barati, Amadou Barrow, Abdul-Monim Mohammad Batiha, Diana Fernanda Bejarano Ramirez, Uzma Iqbal Belgaumi, Alemshet Yirga Berhie, Devidas S Bhagat, Nikha Bhardwaj, Pankaj Bhardwaj, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja, Ali Bijani, Antonio Biondi, Belay Boda Abule Bodicha, Hunduma Amensisa Bojia, Archith Boloor, Cristina Bosetti, Dejana Braithwaite, Nikolay Ivanovich Briko, Zahid A Butt, Luis Alberto Cámera, Raja Chandra Chakinala, Promit Ananyo Chakraborty, Jaykaran Charan, Shu Chen, Jee-Young Jasmine Choi, Sonali Gajanan Choudhari, Fazle Rabbi Chowdhury, Dinh-Toi Chu, Sheng-Chia Chung, Paolo Angelo Cortesi, Benjamin C Cowie, Garland T Culbreth, Omid Dadras, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, Fernando Pio De la Hoz, Sisay Abebe Debela, Mohammed Gebre Dedefo, Feleke Mekonnen Demeke, Takele Gezahegn G Demie, Getu Debalkie Demissie, Meseret Derbew Molla, Abebaw Alemayehu Desta, Deepak Dhamnetiya, Mandira Lamichhane Dhimal, Meghnath Dhimal, Mojtaba Didehdar, Linh Phuong Doan, Fariba Dorostkar, Thomas M Drake, Fatemeh Eghbalian, Michael Ekholuenetale, Iman El Sayed, Maysaa El Sayed Zaki, Muhammed Elhadi, Mohamed A Elmonem, Aisha Elsharkawy, Shymaa Enany, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Sharareh Eskandarieh, Firooz Esmaeilzadeh, Sayeh Ezzikouri, Hossein Farrokhpour, Getahun Fetensa, Florian Fischer, Masoud Foroutan, Mohamed M Gad, Abhay Motiramji Gaidhane, Shilpa Gaidhane, Natalie C Galles, Silvano Gallus, Teferi Gebru Gebremeskel, Eyob Alemayehu Gebreyohannes, Keyghobad Ghadiri, Kazem Ghaffari, Mansour Ghafourifard, Seyyed-Hadi Ghamari, Ahmad Ghashghaee, Ali Gholami, Abdolmajid Gholizadeh, Aima Gilani, Amit Goel, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Giuseppe Gorini, Yitayal Ayalew Goshu, Max G Griswold, Mohammed Ibrahim Mohialdeen Gubari, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Rasool Haddadi, Rabih Halwani, Saeed S Hamid, Samer Hamidi, Asif Hanif, Shafiul Haque, Harapan Harapan, Arief Hargono, Sanam Hariri, Ahmed I Hasaballah, S M Mahmudul Hasan, Soheil Hassanipour, Hadi Hassankhani, Simon I Hay, Khezar Hayat, Golnaz Heidari, Claudiu Herteliu, Demisu Zenbaba Heyi, Kamal Hezam, Ramesh Holla, Mohammad-Salar Hosseini, Mostafa Hosseini, Mehdi Hosseinzadeh, Mihaela Hostiuc, Mowafa Househ, Junjie Huang, Nawfal R Hussein, Ivo Iavicoli, Segun Emmanuel Ibitoye, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Lalu Muhammad Irham, Jessica Y Islam, Nahlah Elkudssiah Ismail, Kathryn H Jacobsen, Farhad Jadidi-Niaragh, Amirreza Javadi Mamaghani, Shubha Jayaram, Ranil Jayawardena, Rime Jebai, Ravi Prakash Jha, Nitin Joseph, Farahnaz Joukar, Billingsley Kaambwa, Ali Kabir, Zubair Kabir, Rohollah Kalhor, Himal Kandel, Tesfaye K Tesfaye Kanko, Rami S Kantar, Ibraheem M Karaye, Bekalu Getnet Kassa, Phillip M Kemp Bohan, Mohammad Keykhaei, Yousef Saleh Khader, Himanshu Khajuria, Gulfaraz Khan, Imteyaz A Khan, Junaid Khan, Moien AB Khan, Javad Khanali, Amir M Khater, Mahalaqua Nazli Khatib, Mahmoud Khodadost, Abdullah T Khoja, Omid Khosravizadeh, Jagdish Khubchandani, Gyu Ri Kim, Hanna Kim, Min Seo Kim, Yun Jin Kim, Jonathan M Kocarnik, Ali-Asghar Kolahi, Rajasekaran Koteeswaran, G Anil Kumar, Carlo La Vecchia, Dharmesh Kumar Lal, Iván Landires, Savita Lasrado, Jeffrey V Lazarus, Caterina Ledda, Doo Woong Lee, Sang-woong Lee, Yeong Yeh Lee, Miriam Levi, Jiarui Li, Stephen S Lim, Stany W Lobo, Platon D Lopukhov, Joana A Loureiro, Jennifer H MacLachlan, Hassan Magdy Abd El Razek, Muhammed Magdy Abd El Razek, Azeem Majeed, Alaa Makki, Mohammad-Reza Malekpour, Reza Malekzadeh, Ahmad Azam Malik, Fariborz Mansour-Ghanaei, Mohammad Ali Mansournia, Francisco Rogerlândio Martins-Melo, Philippa C Matthews, Walter Mendoza, Ritesh G Menezes, Tuomo J Meretoja, Amanual Getnet Mersha, Tomislav Mestrovic, Ted R Miller, Le Huu Nhat Minh, Andreea Mirica, Seyyedmohammadsadeq Mirmoeeni, Erkin M Mirrakhimov, Sanjeev Misra, Prasanna Mithra, Babak Moazen, Ashraf Mohamadkhani, Mokhtar Mohammadi, Shafiu Mohammed, Nagabhishek Moka, Ali H Mokdad, Jalal Moludi, Sara Momtazmanesh, Lorenzo Monasta, Ghobad Moradi, Maliheh Moradzadeh, Rahmatollah Moradzadeh, Paula Moraga, Ebrahim Mostafavi, Sumaira Mubarik, Malaisamy Muniyandi, Christopher J L Murray, Mohsen Naghavi, Mukhammad David Naimzada, Sreenivas Narasimha Swamy, Zuhair S Natto, Biswa Prakash Nayak, Javad Nazari, Ionut Negoi, Serban Mircea Negru, Seyed Aria Nejadghaderi, Sandhya Neupane Kandel, Huong Lan Thi Nguyen, Che Henry Ngwa, Robina Khan Niazi, Chukwudi A Nnaji, Jean Jacques Noubiap, Ali Nowroozi, Virginia Nuñez-Samudio, Bogdan Oancea, Chimedsuren Ochir, Oluwakemi Ololade Odukoya, In-Hwan Oh, Andrew T Olagunju, Babayemi Oluwaseun Olakunde, Ahmed Omar Bali, Emad Omer, Stanislav S Otstavnov, Bilcha Oumer, Jagadish Rao Padubidri, Adrian Pana, Anamika Pandey, Eun-Cheol Park, Fatemeh Pashazadeh Kan, Urvish K Patel, Uttam Paudel, Ionela-Roxana Petcu, Zahra Zahid Piracha, Richard Charles G Pollok, Maarten J Postma, Akram Pourshams, Hossein Poustchi, Mohammad Rabiee, Navid Rabiee, Alireza Rafiei, Sima Rafiei, Pavan Manibettu Raghuram, Mosiur Rahman, Amir Masoud Rahmani, Setyaningrum Rahmawaty, Aashish Rajesh, Priyanga Ranasinghe, Chythra R Rao, Sowmya J Rao, Mahsa Rashidi, Mohammad-Mahdi Rashidi, David Laith Rawaf, Salman Rawaf, Reza Rawassizadeh, Negar Rezaei, Aziz Rezapour, Sahba Rezazadeh-Khadem, Jefferson Antonio Buendia Rodriguez, Godfrey M Rwegerera, Siamak Sabour, Basema Saddik, Mohammad Reza Saeb, Umar Saeed, Amirhossein Sahebkar, KM Saif-Ur-Rahman, Sarvenaz Salahi, Hamideh Salimzadeh, Chethan Sampath, Abdallah M Samy, Juan Sanabria, Francesco Sanmarchi, Milena M Santric-Milicevic, Arash Sarveazad, Brijesh Sathian, Monika Sawhney, Abdul-Aziz Seidu, Sadaf G Sepanlou, Allen Seylani, Saeed Shahabi, Masood Ali Shaikh, Elaheh Shaker, Murad Ziyaudinovich Shakhmardanov, Mohammed Shannawaz, Suchitra M Shenoy, Jeevan K Shetty, Pavanchand H Shetty, Kenji Shibuya, Jae Il Shin, Parnian Shobeiri, Migbar Mekonnen Sibhat, Achintya Dinesh Singh, Jasvinder A Singh, Surjit Singh, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Amir Ali Sohrabpour, Suhang Song, Seidamir Pasha Tabaeian, Eyayou Girma Tadesse, Majid Taheri, Mircea Tampa, Ker-Kan Tan, Ahmad Tavakoli, Abdelghani Tbakhi, Belay Negash Tefera, Arash Tehrani-Banihashemi, Habtamu Molla Tesfaw, Rekha Thapar, Aravind Thavamani, Seyed Abolfazl Tohidast, Daniel Nigusse Tollosa, Maria Elena Tosti, Marcos Roberto Tovani-Palone, Eugenio Traini, Mai Thi Ngoc Tran, Indang Trihandini, Biruk Shalmeno Tusa, Irfan Ullah, Marco Vacante, Sahel Valadan Tahbaz, Pascual R Valdez, Shoban Babu Varthya, Bay Vo, Yasir Waheed, Adisu Birhanu Weldesenbet, Melat Woldemariam, Suowen Xu, Seyed Hossein Yahyazadeh Jabbari, Mehdi Yaseri, Yigizie Yeshaw, Vahit Yiğit, Birhanu Wubale Yirdaw, Naohiro Yonemoto, Chuanhua Yu, Ismaeel Yunusa, Mazyar Zahir, Leila Zaki, Mohammad Zamani, Maryam Zamanian, Mikhail Sergeevich Zastrozhin, Theo Vos, John W Ward, M Ashworth Dirac, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Sheena, Brittney S, Hiebert, Lindsey, Han, Hannah, Ippolito, Helen, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdoli, Amir, Abubaker Ali, Hiwa, Adane, Mesafint Molla, Adegboye, Oyelola A, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afzal, Muhammad Sohail, Afzal, Saira, Aghaie Meybodi, Mohamad, Ahadinezhad, Bahman, Ahinkorah, Bright Opoku, Ahmad, Sajjad, Ahmad, Tauseef, Ahmadi, Sepideh, Ahmed, Haroon, Ahmed, Muktar Beshir, Ahmed Rashid, Tarik, Akalu, Gizachew Taddesse, Aklilu, Addi, Akram, Tayyaba, Al Hamad, Hanadi, Alahdab, Fare, Alem, Adugnaw Zeleke, Alem, Dejene Tsegaye, Alhalaiqa, Fadwa Alhalaiqa Naji, Alhassan, Robert Kaba, Ali, Liaqat, Ali, Muhammad Ashar, Alimohamadi, Yousef, Alipour, Vahid, Alkhayyat, Motasem, Almustanyir, Sami, Al-Raddadi, Rajaa M, Altawalah, Haya, Amini, Saeed, Amu, Hubert, Ancuceanu, Robert, Andrei, Catalina Liliana, Andrei, Tudorel, Anoushiravani, Amir, Ansar, Adnan, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arab-Zozani, Morteza, Argaw, Ayele Mamo, Argaw, Zeleke Gebru, Arshad, Muhammad, Artamonov, Anton A, Ashraf, Tahira, Atlaw, Daniel, Ausloos, Floriane, Ausloos, Marcel, Azadnajafabad, Sina, Azangou-Khyavy, Mohammadreza, Azari Jafari, Amirhossein, Azarian, Ghasem, Bagheri, Sayna, Bahadory, Saeed, Baig, Atif Amin, Banach, Maciej, Barati, Nastaran, Barrow, Amadou, Batiha, Abdul-Monim Mohammad, Bejarano Ramirez, Diana Fernanda, Belgaumi, Uzma Iqbal, Berhie, Alemshet Yirga, Bhagat, Devidas S, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bhojaraja, Vijayalakshmi S, Bijani, Ali, Biondi, Antonio, Bodicha, Belay Boda Abule, Bojia, Hunduma Amensisa, Boloor, Archith, Bosetti, Cristina, Braithwaite, Dejana, Briko, Nikolay Ivanovich, Butt, Zahid A, Cámera, Luis Alberto, Chakinala, Raja Chandra, Chakraborty, Promit Ananyo, Charan, Jaykaran, Chen, Shu, Choi, Jee-Young Jasmine, Choudhari, Sonali Gajanan, Chowdhury, Fazle Rabbi, Chu, Dinh-Toi, Chung, Sheng-Chia, Cortesi, Paolo Angelo, Cowie, Benjamin C, Culbreth, Garland T, Dadras, Omid, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, De la Hoz, Fernando Pio, Debela, Sisay Abebe, Dedefo, Mohammed Gebre, Demeke, Feleke Mekonnen, Demie, Takele Gezahegn G, Demissie, Getu Debalkie, Derbew Molla, Meseret, Desta, Abebaw Alemayehu, Dhamnetiya, Deepak, Dhimal, Mandira Lamichhane, Dhimal, Meghnath, Didehdar, Mojtaba, Doan, Linh Phuong, Dorostkar, Fariba, Drake, Thomas M, Eghbalian, Fatemeh, Ekholuenetale, Michael, El Sayed, Iman, El Sayed Zaki, Maysaa, Elhadi, Muhammed, Elmonem, Mohamed A, Elsharkawy, Aisha, Enany, Shymaa, Enyew, Daniel Berhanie, Erkhembayar, Ryenchindorj, Eskandarieh, Sharareh, Esmaeilzadeh, Firooz, Ezzikouri, Sayeh, Farrokhpour, Hossein, Fetensa, Getahun, Fischer, Florian, Foroutan, Masoud, Gad, Mohamed M, Gaidhane, Abhay Motiramji, Gaidhane, Shilpa, Galles, Natalie C, Gallus, Silvano, Gebremeskel, Teferi Gebru, Gebreyohannes, Eyob Alemayehu, Ghadiri, Keyghobad, Ghaffari, Kazem, Ghafourifard, Mansour, Ghamari, Seyyed-Hadi, Ghashghaee, Ahmad, Gholami, Ali, Gholizadeh, Abdolmajid, Gilani, Aima, Goel, Amit, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Gorini, Giuseppe, Goshu, Yitayal Ayalew, Griswold, Max G, Gubari, Mohammed Ibrahim Mohialdeen, Gupta, Bhawna, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Haddadi, Rasool, Halwani, Rabih, Hamid, Saeed S, Hamidi, Samer, Hanif, Asif, Haque, Shafiul, Harapan, Harapan, Hargono, Arief, Hariri, Sanam, Hasaballah, Ahmed I, Hasan, S M Mahmudul, Hassanipour, Soheil, Hassankhani, Hadi, Hay, Simon I, Hayat, Khezar, Heidari, Golnaz, Herteliu, Claudiu, Heyi, Demisu Zenbaba, Hezam, Kamal, Holla, Ramesh, Hosseini, Mohammad-Salar, Hosseini, Mostafa, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Househ, Mowafa, Huang, Junjie, Hussein, Nawfal R, Iavicoli, Ivo, Ibitoye, Segun Emmanuel, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Irham, Lalu Muhammad, Islam, Jessica Y, Ismail, Nahlah Elkudssiah, Jacobsen, Kathryn H, Jadidi-Niaragh, Farhad, Javadi Mamaghani, Amirreza, Jayaram, Shubha, Jayawardena, Ranil, Jebai, Rime, Jha, Ravi Prakash, Joseph, Nitin, Joukar, Farahnaz, Kaambwa, Billingsley, Kabir, Ali, Kabir, Zubair, Kalhor, Rohollah, Kandel, Himal, Kanko, Tesfaye K Tesfaye, Kantar, Rami S, Karaye, Ibraheem M, Kassa, Bekalu Getnet, Kemp Bohan, Phillip M, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khan, Gulfaraz, Khan, Imteyaz A, Khan, Junaid, Khan, Moien AB, Khanali, Javad, Khater, Amir M, Khatib, Mahalaqua Nazli, Khodadost, Mahmoud, Khoja, Abdullah T, Khosravizadeh, Omid, Khubchandani, Jagdish, Kim, Gyu Ri, Kim, Hanna, Kim, Min Seo, Kim, Yun Jin, Kocarnik, Jonathan M, Kolahi, Ali-Asghar, Koteeswaran, Rajasekaran, Kumar, G Anil, La Vecchia, Carlo, Lal, Dharmesh Kumar, Landires, Iván, Lasrado, Savita, Lazarus, Jeffrey V, Ledda, Caterina, Lee, Doo Woong, Lee, Sang-woong, Lee, Yeong Yeh, Levi, Miriam, Li, Jiarui, Lim, Stephen S, Lobo, Stany W, Lopukhov, Platon D, Loureiro, Joana A, MacLachlan, Jennifer H, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Muhammed, Majeed, Azeem, Makki, Alaa, Malekpour, Mohammad-Reza, Malekzadeh, Reza, Malik, Ahmad Azam, Mansour-Ghanaei, Fariborz, Mansournia, Mohammad Ali, Martins-Melo, Francisco Rogerlândio, Matthews, Philippa C, Mendoza, Walter, Menezes, Ritesh G, Meretoja, Tuomo J, Mersha, Amanual Getnet, Mestrovic, Tomislav, Miller, Ted R, Minh, Le Huu Nhat, Mirica, Andreea, Mirmoeeni, Seyyedmohammadsadeq, Mirrakhimov, Erkin M, Misra, Sanjeev, Mithra, Prasanna, Moazen, Babak, Mohamadkhani, Ashraf, Mohammadi, Mokhtar, Mohammed, Shafiu, Moka, Nagabhishek, Mokdad, Ali H, Moludi, Jalal, Momtazmanesh, Sara, Monasta, Lorenzo, Moradi, Ghobad, Moradzadeh, Maliheh, Moradzadeh, Rahmatollah, Moraga, Paula, Mostafavi, Ebrahim, Mubarik, Sumaira, Muniyandi, Malaisamy, Murray, Christopher J L, Naghavi, Mohsen, Naimzada, Mukhammad David, Narasimha Swamy, Sreeniva, Natto, Zuhair S, Nayak, Biswa Prakash, Nazari, Javad, Negoi, Ionut, Negru, Serban Mircea, Nejadghaderi, Seyed Aria, Neupane Kandel, Sandhya, Nguyen, Huong Lan Thi, Ngwa, Che Henry, Niazi, Robina Khan, Nnaji, Chukwudi A, Noubiap, Jean Jacque, Nowroozi, Ali, Nuñez-Samudio, Virginia, Oancea, Bogdan, Ochir, Chimedsuren, Odukoya, Oluwakemi Ololade, Oh, In-Hwan, Olagunju, Andrew T, Olakunde, Babayemi Oluwaseun, Omar Bali, Ahmed, Omer, Emad, Otstavnov, Stanislav S, Oumer, Bilcha, Padubidri, Jagadish Rao, Pana, Adrian, Pandey, Anamika, Park, Eun-Cheol, Pashazadeh Kan, Fatemeh, Patel, Urvish K, Paudel, Uttam, Petcu, Ionela-Roxana, Piracha, Zahra Zahid, Pollok, Richard Charles G, Postma, Maarten J, Pourshams, Akram, Poustchi, Hossein, Rabiee, Mohammad, Rabiee, Navid, Rafiei, Alireza, Rafiei, Sima, Raghuram, Pavan Manibettu, Rahman, Mosiur, Rahmani, Amir Masoud, Rahmawaty, Setyaningrum, Rajesh, Aashish, Ranasinghe, Priyanga, Rao, Chythra R, Rao, Sowmya J, Rashidi, Mahsa, Rashidi, Mohammad-Mahdi, Rawaf, David Laith, Rawaf, Salman, Rawassizadeh, Reza, Rezaei, Negar, Rezapour, Aziz, Rezazadeh-Khadem, Sahba, Rodriguez, Jefferson Antonio Buendia, Rwegerera, Godfrey M, Sabour, Siamak, Saddik, Basema, Saeb, Mohammad Reza, Saeed, Umar, Sahebkar, Amirhossein, Saif-Ur-Rahman, KM, Salahi, Sarvenaz, Salimzadeh, Hamideh, Sampath, Chethan, Samy, Abdallah M, Sanabria, Juan, Sanmarchi, Francesco, Santric-Milicevic, Milena M, Sarveazad, Arash, Sathian, Brijesh, Sawhney, Monika, Seidu, Abdul-Aziz, Sepanlou, Sadaf G, Seylani, Allen, Shahabi, Saeed, Shaikh, Masood Ali, Shaker, Elaheh, Shakhmardanov, Murad Ziyaudinovich, Shannawaz, Mohammed, Shenoy, Suchitra M, Shetty, Jeevan K, Shetty, Pavanchand H, Shibuya, Kenji, Shin, Jae Il, Shobeiri, Parnian, Sibhat, Migbar Mekonnen, Singh, Achintya Dinesh, Singh, Jasvinder A, Singh, Surjit, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Sohrabpour, Amir Ali, Song, Suhang, Tabaeian, Seidamir Pasha, Tadesse, Eyayou Girma, Taheri, Majid, Tampa, Mircea, Tan, Ker-Kan, Tavakoli, Ahmad, Tbakhi, Abdelghani, Tefera, Belay Negash, Tehrani-Banihashemi, Arash, Tesfaw, Habtamu Molla, Thapar, Rekha, Thavamani, Aravind, Tohidast, Seyed Abolfazl, Tollosa, Daniel Nigusse, Tosti, Maria Elena, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Mai Thi Ngoc, Trihandini, Indang, Tusa, Biruk Shalmeno, Ullah, Irfan, Vacante, Marco, Valadan Tahbaz, Sahel, Valdez, Pascual R, Varthya, Shoban Babu, Vo, Bay, Waheed, Yasir, Weldesenbet, Adisu Birhanu, Woldemariam, Melat, Xu, Suowen, Yahyazadeh Jabbari, Seyed Hossein, Yaseri, Mehdi, Yeshaw, Yigizie, Yiğit, Vahit, Yirdaw, Birhanu Wubale, Yonemoto, Naohiro, Yu, Chuanhua, Yunusa, Ismaeel, Zahir, Mazyar, Zaki, Leila, Zamani, Mohammad, Zamanian, Maryam, Zastrozhin, Mikhail Sergeevich, Vos, Theo, Ward, John W, Dirac, M Ashworth, Sheena, B, Hiebert, L, Han, H, Ippolito, H, Abbasi-Kangevari, M, Abbasi-Kangevari, Z, Abbastabar, H, Abdoli, A, Abubaker Ali, H, Adane, M, Adegboye, O, Adnani, Q, Advani, S, Afzal, M, Afzal, S, Aghaie Meybodi, M, Ahadinezhad, B, Ahinkorah, B, Ahmad, S, Ahmad, T, Ahmadi, S, Ahmed, H, Ahmed, M, Rashid, T, Akalu, G, Aklilu, A, Akram, T, Al Hamad, H, Alahdab, F, Alem, A, Alem, D, Alhalaiqa, F, Alhassan, R, Ali, L, Ali, M, Alimohamadi, Y, Alipour, V, Alkhayyat, M, Almustanyir, S, Al-Raddadi, R, Altawalah, H, Amini, S, Amu, H, Ancuceanu, R, Andrei, C, Andrei, T, Anoushiravani, A, Ansar, A, Anyasodor, A, Arabloo, J, Arab-Zozani, M, Argaw, A, Argaw, Z, Arshad, M, Artamonov, A, Ashraf, T, Atlaw, D, Ausloos, F, Ausloos, M, Azadnajafabad, S, Azangou-Khyavy, M, Azari Jafari, A, Azarian, G, Bagheri, S, Bahadory, S, Baig, A, Banach, M, Barati, N, Barrow, A, Batiha, A, Bejarano Ramirez, D, Belgaumi, U, Berhie, A, Bhagat, D, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bhojaraja, V, Bijani, A, Biondi, A, Bodicha, B, Bojia, H, Boloor, A, Bosetti, C, Braithwaite, D, Briko, N, Butt, Z, Camera, L, Chakinala, R, Chakraborty, P, Charan, J, Chen, S, Choi, J, Choudhari, S, Chowdhury, F, Chu, D, Chung, S, Cortesi, P, Cowie, B, Culbreth, G, Dadras, O, Dai, X, Dandona, L, Dandona, R, De La Hoz, F, Debela, S, Dedefo, M, Demeke, F, Demie, T, Demissie, G, Derbew Molla, M, Desta, A, Dhamnetiya, D, Dhimal, M, Didehdar, M, Doan, L, Dorostkar, F, Drake, T, Eghbalian, F, Ekholuenetale, M, El Sayed, I, El Sayed Zaki, M, Elhadi, M, Elmonem, M, Elsharkawy, A, Enany, S, Enyew, D, Erkhembayar, R, Eskandarieh, S, Esmaeilzadeh, F, Ezzikouri, S, Farrokhpour, H, Fetensa, G, Fischer, F, Foroutan, M, Gad, M, Gaidhane, A, Gaidhane, S, Galles, N, Gallus, S, Gebremeskel, T, Gebreyohannes, E, Ghadiri, K, Ghaffari, K, Ghafourifard, M, Ghamari, S, Ghashghaee, A, Gholami, A, Gholizadeh, A, Gilani, A, Goel, A, Golechha, M, Goleij, P, Golinelli, D, Gorini, G, Goshu, Y, Griswold, M, Gubari, M, Gupta, B, Gupta, S, Gupta, V, Haddadi, R, Halwani, R, Hamid, S, Hamidi, S, Hanif, A, Haque, S, Harapan, H, Hargono, A, Hariri, S, Hasaballah, A, Hasan, S, Hassanipour, S, Hassankhani, H, Hay, S, Hayat, K, Heidari, G, Herteliu, C, Heyi, D, Hezam, K, Holla, R, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Househ, M, Huang, J, Hussein, N, Iavicoli, I, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Irham, L, Islam, J, Ismail, N, Jacobsen, K, Jadidi-Niaragh, F, Javadi Mamaghani, A, Jayaram, S, Jayawardena, R, Jebai, R, Jha, R, Joseph, N, Joukar, F, Kaambwa, B, Kabir, A, Kabir, Z, Kalhor, R, Kandel, H, Kanko, T, Kantar, R, Karaye, I, Kassa, B, Kemp Bohan, P, Keykhaei, M, Khader, Y, Khajuria, H, Khan, G, Khan, I, Khan, J, Khan, M, Khanali, J, Khater, A, Khatib, M, Khodadost, M, Khoja, A, Khosravizadeh, O, Khubchandani, J, Kim, G, Kim, H, Kim, M, Kim, Y, Kocarnik, J, Kolahi, A, Koteeswaran, R, Kumar, G, La Vecchia, C, Lal, D, Landires, I, Lasrado, S, Lazarus, J, Ledda, C, Lee, D, Lee, S, Lee, Y, Levi, M, Li, J, Lim, S, Lobo, S, Lopukhov, P, Loureiro, J, Maclachlan, J, Magdy Abd El Razek, H, Magdy Abd El Razek, M, Majeed, A, Makki, A, Malekpour, M, Malekzadeh, R, Malik, A, Mansour-Ghanaei, F, Mansournia, M, Martins-Melo, F, Matthews, P, Mendoza, W, Menezes, R, Meretoja, T, Mersha, A, Mestrovic, T, Miller, T, Minh, L, Mirica, A, Mirmoeeni, S, Mirrakhimov, E, Misra, S, Mithra, P, Moazen, B, Mohamadkhani, A, Mohammadi, M, Mohammed, S, Moka, N, Mokdad, A, Moludi, J, Momtazmanesh, S, Monasta, L, Moradi, G, Moradzadeh, M, Moradzadeh, R, Moraga, P, Mostafavi, E, Mubarik, S, Muniyandi, M, Murray, C, Naghavi, M, Naimzada, M, Narasimha Swamy, S, Natto, Z, Nayak, B, Nazari, J, Negoi, I, Negru, S, Nejadghaderi, S, Neupane Kandel, S, Nguyen, H, Ngwa, C, Niazi, R, Nnaji, C, Noubiap, J, Nowroozi, A, Nunez-Samudio, V, Oancea, B, Ochir, C, Odukoya, O, Oh, I, Olagunju, A, Olakunde, B, Omar Bali, A, Omer, E, Otstavnov, S, Oumer, B, Padubidri, J, Pana, A, Pandey, A, Park, E, Pashazadeh Kan, F, Patel, U, Paudel, U, Petcu, I, Piracha, Z, Pollok, R, Postma, M, Pourshams, A, Poustchi, H, Rabiee, M, Rabiee, N, Rafiei, A, Rafiei, S, Raghuram, P, Rahman, M, Rahmani, A, Rahmawaty, S, Rajesh, A, Ranasinghe, P, Rao, C, Rao, S, Rashidi, M, Rawaf, D, Rawaf, S, Rawassizadeh, R, Rezaei, N, Rezapour, A, Rezazadeh-Khadem, S, Rodriguez, J, Rwegerera, G, Sabour, S, Saddik, B, Saeb, M, Saeed, U, Sahebkar, A, Saif-Ur-Rahman, K, Salahi, S, Salimzadeh, H, Sampath, C, Samy, A, Sanabria, J, Sanmarchi, F, Santric-Milicevic, M, Sarveazad, A, Sathian, B, Sawhney, M, Seidu, A, Sepanlou, S, Seylani, A, Shahabi, S, Shaikh, M, Shaker, E, Shakhmardanov, M, Shannawaz, M, Shenoy, S, Shetty, J, Shetty, P, Shibuya, K, Shin, J, Shobeiri, P, Sibhat, M, Singh, A, Singh, J, Singh, S, Skryabin, V, Skryabina, A, Sohrabpour, A, Song, S, Tabaeian, S, Tadesse, E, Taheri, M, Tampa, M, Tan, K, Tavakoli, A, Tbakhi, A, Tefera, B, Tehrani-Banihashemi, A, Tesfaw, H, Thapar, R, Thavamani, A, Tohidast, S, Tollosa, D, Tosti, M, Tovani-Palone, M, Traini, E, Tran, M, Trihandini, I, Tusa, B, Ullah, I, Vacante, M, Valadan Tahbaz, S, Valdez, P, Varthya, S, Vo, B, Waheed, Y, Weldesenbet, A, Woldemariam, M, Xu, S, Yahyazadeh Jabbari, S, Yaseri, M, Yeshaw, Y, Yigit, V, Yirdaw, B, Yonemoto, N, Yu, C, Yunusa, I, Zahir, M, Zaki, L, Zamani, M, Zamanian, M, Zastrozhin, M, Vos, T, Ward, J, Dirac, M, Helsinki University Hospital Area, HUS Comprehensive Cancer Center, Sheena, B. S., Hiebert, L., Han, H., Ippolito, H., Abbasi-Kangevari, M., Abbasi-Kangevari, Z., Abbastabar, H., Abdoli, A., Abubaker Ali, H., Adane, M. M., Adegboye, O. A., Adnani, Q. E. S., Advani, S. M., Afzal, M. S., Afzal, S., Aghaie Meybodi, M., Ahadinezhad, B., Ahinkorah, B. O., Ahmad, S., Ahmad, T., Ahmadi, S., Ahmed, H., Ahmed, M. B., Rashid, T. A., Akalu, G. T., Aklilu, A., Akram, T., Al Hamad, H., Alahdab, F., Alem, A., Alem, D. T., Alhalaiqa, F. A. N., Alhassan, R. K., Ali, L., Ali, M. A., Alimohamadi, Y., Alipour, V., Alkhayyat, M., Almustanyir, S., Al-Raddadi, R. M., Altawalah, H., Amini, S., Amu, H., Ancuceanu, R., Andrei, C. L., Andrei, T., Anoushiravani, A., Ansar, A., Anyasodor, A. E., Arabloo, J., Arab-Zozani, M., Argaw, A. M., Argaw, Z. G., Arshad, M., Artamonov, A. A., Ashraf, T., Atlaw, D., Ausloos, F., Ausloos, M., Azadnajafabad, S., Azangou-Khyavy, M., Azari Jafari, A., Azarian, G., Bagheri, S., Bahadory, S., Baig, A. A., Banach, M., Barati, N., Barrow, A., Batiha, A. -M. M., Bejarano Ramirez, D. F., Belgaumi, U. I., Berhie, A. Y., Bhagat, D. S., Bhardwaj, N., Bhardwaj, P., Bhattacharyya, K., Bhojaraja, V. S., Bijani, A., Biondi, A., Bodicha, B. B. A., Bojia, H. A., Boloor, A., Bosetti, C., Braithwaite, D., Briko, N. I., Butt, Z. A., Camera, L. A., Chakinala, R. C., Chakraborty, P. A., Charan, J., Chen, S., Choi, J. -Y. J., Choudhari, S. G., Chowdhury, F. R., Chu, D. -T., Chung, S. -C., Cortesi, P. A., Cowie, B. C., Culbreth, G. T., Dadras, O., Dai, X., Dandona, L., Dandona, R., De La Hoz, F. P., Debela, S. A., Dedefo, M. G., Demeke, F. M., Demie, T. G. G., Demissie, G. D., Derbew Molla, M., Desta, A. A., Dhamnetiya, D., Dhimal, M. L., Dhimal, M., Didehdar, M., Doan, L. P., Dorostkar, F., Drake, T. M., Eghbalian, F., Ekholuenetale, M., El Sayed, I., El Sayed Zaki, M., Elhadi, M., Elmonem, M. A., Elsharkawy, A., Enany, S., Enyew, D. B., Erkhembayar, R., Eskandarieh, S., Esmaeilzadeh, F., Ezzikouri, S., Farrokhpour, H., Fetensa, G., Fischer, F., Foroutan, M., Gad, M. M., Gaidhane, A. M., Gaidhane, S., Galles, N. C., Gallus, S., Gebremeskel, T. G., Gebreyohannes, E. A., Ghadiri, K., Ghaffari, K., Ghafourifard, M., Ghamari, S. -H., Ghashghaee, A., Gholami, A., Gholizadeh, A., Gilani, A., Goel, A., Golechha, M., Goleij, P., Golinelli, D., Gorini, G., Goshu, Y. A., Griswold, M. G., Gubari, M. I. M., Gupta, B., Gupta, S., Gupta, V. B., Gupta, V. K., Haddadi, R., Halwani, R., Hamid, S. S., Hamidi, S., Hanif, A., Haque, S., Harapan, H., Hargono, A., Hariri, S., Hasaballah, A. I., Hasan, S. M. M., Hassanipour, S., Hassankhani, H., Hay, S. I., Hayat, K., Heidari, G., Herteliu, C., Heyi, D. Z., Hezam, K., Holla, R., Hosseini, M. -S., Hosseini, M., Hosseinzadeh, M., Hostiuc, M., Househ, M., Huang, J., Hussein, N. R., Iavicoli, I., Ibitoye, S. E., Ilesanmi, O. S., Ilic, I. M., Ilic, M. D., Irham, L. M., Islam, J. Y., Ismail, N. E., Jacobsen, K. H., Jadidi-Niaragh, F., Javadi Mamaghani, A., Jayaram, S., Jayawardena, R., Jebai, R., Jha, R. P., Joseph, N., Joukar, F., Kaambwa, B., Kabir, A., Kabir, Z., Kalhor, R., Kandel, H., Kanko, T. K. T., Kantar, R. S., Karaye, I. M., Kassa, B. G., Kemp Bohan, P. M., Keykhaei, M., Khader, Y. S., Khajuria, H., Khan, G., Khan, I. A., Khan, J., Khan, M. A., Khanali, J., Khater, A. M., Khatib, M. N., Khodadost, M., Khoja, A. T., Khosravizadeh, O., Khubchandani, J., Kim, G. R., Kim, H., Kim, M. S., Kim, Y. J., Kocarnik, J. M., Kolahi, A. -A., Koteeswaran, R., Kumar, G. A., La Vecchia, C., Lal, D. K., Landires, I., Lasrado, S., Lazarus, J. V., Ledda, C., Lee, D. W., Lee, S. -W., Lee, Y. Y., Levi, M., Li, J., Lim, S. S., Lobo, S. W., Lopukhov, P. D., Loureiro, J. A., Maclachlan, J. H., Magdy Abd El Razek, H., Magdy Abd El Razek, M., Majeed, A., Makki, A., Malekpour, M. -R., Malekzadeh, R., Malik, A. A., Mansour-Ghanaei, F., Mansournia, M. A., Martins-Melo, F. R., Matthews, P. C., Mendoza, W., Menezes, R. G., Meretoja, T. J., Mersha, A. G., Mestrovic, T., Miller, T. R., Minh, L. H. N., Mirica, A., Mirmoeeni, S., Mirrakhimov, E. M., Misra, S., Mithra, P., Moazen, B., Mohamadkhani, A., Mohammadi, M., Mohammed, S., Moka, N., Mokdad, A. H., Moludi, J., Momtazmanesh, S., Monasta, L., Moradi, G., Moradzadeh, M., Moradzadeh, R., Moraga, P., Mostafavi, E., Mubarik, S., Muniyandi, M., Murray, C. J. L., Naghavi, M., Naimzada, M. D., Narasimha Swamy, S., Natto, Z. S., Nayak, B. P., Nazari, J., Negoi, I., Negru, S. M., Nejadghaderi, S. A., Neupane Kandel, S., Nguyen, H. L. T., Ngwa, C. H., Niazi, R. K., Nnaji, C. A., Noubiap, J. J., Nowroozi, A., Nunez-Samudio, V., Oancea, B., Ochir, C., Odukoya, O. O., Oh, I. -H., Olagunju, A. T., Olakunde, B. O., Omar Bali, A., Omer, E., Otstavnov, S. S., Oumer, B., Padubidri, J. R., Pana, A., Pandey, A., Park, E. -C., Pashazadeh Kan, F., Patel, U. K., Paudel, U., Petcu, I. -R., Piracha, Z. Z., Pollok, R. C. G., Postma, M. J., Pourshams, A., Poustchi, H., Rabiee, M., Rabiee, N., Rafiei, A., Rafiei, S., Raghuram, P. M., Rahman, M., Rahmani, A. M., Rahmawaty, S., Rajesh, A., Ranasinghe, P., Rao, C. R., Rao, S. J., Rashidi, M., Rashidi, M. -M., Rawaf, D. L., Rawaf, S., Rawassizadeh, R., Rezaei, N., Rezapour, A., Rezazadeh-Khadem, S., Rodriguez, J. A. B., Rwegerera, G. M., Sabour, S., Saddik, B., Saeb, M. R., Saeed, U., Sahebkar, A., Saif-Ur-Rahman, K. M., Salahi, S., Salimzadeh, H., Sampath, C., Samy, A. M., Sanabria, J., Sanmarchi, F., Santric-Milicevic, M. M., Sarveazad, A., Sathian, B., Sawhney, M., Seidu, A. -A., Sepanlou, S. G., Seylani, A., Shahabi, S., Shaikh, M. A., Shaker, E., Shakhmardanov, M. Z., Shannawaz, M., Shenoy, S. M., Shetty, J. K., Shetty, P. H., Shibuya, K., Shin, J. I., Shobeiri, P., Sibhat, M. M., Singh, A. D., Singh, J. A., Singh, S., Skryabin, V. Y., Skryabina, A. A., Sohrabpour, A. A., Song, S., Tabaeian, S. P., Tadesse, E. G., Taheri, M., Tampa, M., Tan, K. -K., Tavakoli, A., Tbakhi, A., Tefera, B. N., Tehrani-Banihashemi, A., Tesfaw, H. M., Thapar, R., Thavamani, A., Tohidast, S. A., Tollosa, D. N., Tosti, M. E., Tovani-Palone, M. R., Traini, E., Tran, M. T. N., Trihandini, I., Tusa, B. S., Ullah, I., Vacante, M., Valadan Tahbaz, S., Valdez, P. R., Varthya, S. B., Vo, B., Waheed, Y., Weldesenbet, A. B., Woldemariam, M., Xu, S., Yahyazadeh Jabbari, S. H., Yaseri, M., Yeshaw, Y., Yigit, V., Yirdaw, B. W., Yonemoto, N., Yu, C., Yunusa, I., Zahir, M., Zaki, L., Zamani, M., Zamanian, M., Zastrozhin, M. S., Vos, T., Ward, J. W., and Dirac, M. A.
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Liver Cirrhosis ,Hepatology ,Seroepidemiologic Studies ,3121 General medicine, internal medicine and other clinical medicine ,Liver Neoplasms ,Gastroenterology ,Humans ,Bayes Theorem ,HBV, Global burden of diseases, HCC, Cirrhosis ,Child ,Hepatitis B ,Global Burden of Disease - Abstract
Publisher Copyright: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Combating viral hepatitis is part of the UN Sustainable Development Goals (SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector Strategy on Viral Hepatitis (WHO-GHSS) and Interim Guidance for Country Validation of Viral Hepatitis Elimination (WHO Interim Guidance). We estimated the global, regional, and national prevalence of hepatitis B virus (HBV), as well as mortality and disability-adjusted life-years (DALYs) due to HBV, as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This included estimates for 194 WHO member states, for which we compared our estimates to WHO elimination targets. Methods: The primary data sources were population-based serosurveys, claims and hospital discharges, cancer registries, vital registration systems, and published case series. We estimated chronic HBV infection and the burden of HBV-related diseases, defined as an aggregate of cirrhosis due to hepatitis B, liver cancer due to hepatitis B, and acute hepatitis B. We used DisMod-MR 2.1, a Bayesian mixed-effects meta-regression tool, to estimate the prevalence of chronic HBV infection, cirrhosis, and aetiological proportions of cirrhosis. We used mortality-to-incidence ratios modelled with spatiotemporal Gaussian process regression to estimate the incidence of liver cancer. We used the Cause of Death Ensemble modelling (CODEm) model, a tool that selects models and covariates on the basis of out-of-sample performance, to estimate mortality due to cirrhosis, liver cancer, and acute hepatitis B. Findings: In 2019, the estimated global, all-age prevalence of chronic HBV infection was 4·1% (95% uncertainty interval [UI] 3·7 to 4·5), corresponding to 316 million (284 to 351) infected people. There was a 31·3% (29·0 to 33·9) decline in all-age prevalence between 1990 and 2019, with a more marked decline of 76·8% (76·2 to 77·5) in prevalence in children younger than 5 years. HBV-related diseases resulted in 555 000 global deaths (487 000 to 630 000) in 2019. The number of HBV-related deaths increased between 1990 and 2019 (by 5·9% [–5·6 to 19·2]) and between 2015 and 2019 (by 2·9% [–5·9 to 11·3]). By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. We compared estimates for 2019 in 194 WHO locations to WHO-GHSS 2020 targets, and found that four countries achieved a 10% reduction in deaths, 15 countries achieved a 30% reduction in new cases, and 147 countries achieved a 1% prevalence in children younger than 5 years. As of 2019, 68 of 194 countries had already achieved the 2030 target proposed in WHO Interim Guidance of an all-age HBV-related death rate of four per 100 000. Interpretation: The prevalence of chronic HBV infection declined over time, particularly in children younger than 5 years, since the introduction of hepatitis B vaccination. HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and cohort effects. By 2019, many countries had met the interim seroprevalence target for children younger than 5 years, but few countries had met the WHO-GHSS interim targets for deaths and new cases. Progress according to all indicators must be accelerated to meet 2030 targets, and there are marked disparities in burden and progress across the world. HBV interventions, such as vaccination, testing, and treatment, must be strategically supported and scaled up to achieve elimination. Funding: Bill & Melinda Gates Foundation.
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- 2022
9. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
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Hmwe Hmwe Kyu, Avina Vongpradith, Sarah Brooke Sirota, Amanda Novotney, Christopher E Troeger, Matthew C Doxey, Rose G Bender, Jorge R Ledesma, Molly H Biehl, Samuel B Albertson, Joseph Jon Frostad, Katrin Burkart, Fiona B Bennitt, Jeff T Zhao, William M Gardner, Hailey Hagins, Dana Bryazka, Regina-Mae Villanueva Dominguez, Semagn Mekonnen Abate, Michael Abdelmasseh, Amir Abdoli, Gholamreza Abdoli, Aidin Abedi, Vida Abedi, Tadesse M Abegaz, Hassan Abidi, Richard Gyan Aboagye, Hassan Abolhassani, Yonas Derso Abtew, Hiwa Abubaker Ali, Eman Abu-Gharbieh, Ahmed Abu-Zaid, Kidist Adamu, Isaac Yeboah Addo, Oyelola A Adegboye, Mohammad Adnan, Qorinah Estiningtyas Sakilah Adnani, Muhammad Sohail Afzal, Saira Afzal, Bright Opoku Ahinkorah, Aqeel Ahmad, Araz Ramazan Ahmad, Sajjad Ahmad, Ali Ahmadi, Sepideh Ahmadi, Haroon Ahmed, Jivan Qasim Ahmed, Tarik Ahmed Rashid, Mostafa Akbarzadeh-Khiavi, Hanadi Al Hamad, Luciana Albano, Mamoon A Aldeyab, Bezatu Mengistie Alemu, Kefyalew Addis Alene, Abdelazeem M Algammal, Fadwa Alhalaiqa Naji Alhalaiqa, Robert Kaba Alhassan, Beriwan Abdulqadir Ali, Liaqat Ali, Musa Mohammed Ali, Syed Shujait Ali, Yousef Alimohamadi, Vahid Alipour, Adel Al-Jumaily, Syed Mohamed Aljunid, Sami Almustanyir, Rajaa M Al-Raddadi, Rami H Hani Al-Rifai, Saif Aldeen S AlRyalat, Nelson Alvis-Guzman, Nelson J Alvis-Zakzuk, Edward Kwabena Ameyaw, Javad Javad Aminian Dehkordi, John H Amuasi, Dickson A Amugsi, Etsay Woldu Anbesu, Adnan Ansar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Demelash Areda, Ayele Mamo Argaw, Zeleke Gebru Argaw, Judie Arulappan, Raphael Taiwo Aruleba, Mulusew A Asemahagn, Seyyed Shamsadin Athari, Daniel Atlaw, Engi F Attia, Sameh Attia, Avinash Aujayeb, Tewachew Awoke, Tegegn Mulatu Ayana, Martin Amogre Ayanore, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Samad Azari, Amirhossein Azari Jafari, Muhammad Badar, Ashish D Badiye, Nayereh Baghcheghi, Sara Bagherieh, Atif Amin Baig, Maciej Banach, Indrajit Banerjee, Mainak Bardhan, Francesco Barone-Adesi, Hiba Jawdat Barqawi, Amadou Barrow, Azadeh Bashiri, Quique Bassat, Abdul-Monim Mohammad Batiha, Abate Bekele Belachew, Melaku Ashagrie Belete, Uzma Iqbal Belgaumi, Akshaya Srikanth Bhagavathula, Nikha Bhardwaj, Pankaj Bhardwaj, Parth Bhatt, Vijayalakshmi S Bhojaraja, Zulfiqar A Bhutta, Soumitra S Bhuyan, Ali Bijani, Saeid Bitaraf, Belay Boda Abule Bodicha, Nikolay Ivanovich Briko, Danilo Buonsenso, Muhammad Hammad Butt, Jiao Cai, Paulo Camargos, Luis Alberto Cámera, Promit Ananyo Chakraborty, Muluken Genetu Chanie, Jaykaran Charan, Vijay Kumar Chattu, Patrick R Ching, Sungchul Choi, Yuen Yu Chong, Sonali Gajanan Choudhari, Enayet Karim Chowdhury, Devasahayam J Christopher, Dinh-Toi Chu, Natalie L Cobb, Aaron J Cohen, Natália Cruz-Martins, Omid Dadras, Fentaw Teshome Dagnaw, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, An Thi Minh Dao, Sisay Abebe Debela, Biniyam Demisse, Fitsum Wolde Demisse, Solomon Demissie, Diriba Dereje, Hardik Dineshbhai Desai, Abebaw Alemayehu Desta, Belay Desye, Sameer Dhingra, Nancy Diao, Daniel Diaz, Lankamo Ena Digesa, Linh Phuong Doan, Milad Dodangeh, Deepa Dongarwar, Fariba Dorostkar, Wendel Mombaque dos Santos, Haneil Larson Dsouza, Eleonora Dubljanin, Oyewole Christopher Durojaiye, Hisham Atan Edinur, Elham Ehsani-Chimeh, Ebrahim Eini, Michael Ekholuenetale, Temitope Cyrus Ekundayo, Eman D El Desouky, Iman El Sayed, Maysaa El Sayed Zaki, Muhammed Elhadi, Ahmed Mahmoud Rabie Elkhapery, Amir Emami, Luchuo Engelbert Bain, Ryenchindorj Erkhembayar, Farshid Etaee, Mohamad Ezati Asar, Adeniyi Francis Fagbamigbe, Shahab Falahi, Aida Fallahzadeh, Anwar Faraj, Emerito Jose A Faraon, Ali Fatehizadeh, Pietro Ferrara, Allegra Allegra Ferrari, Getahun Fetensa, Florian Fischer, Joanne Flavel, Masoud Foroutan, Peter Andras Gaal, Abhay Motiramji Gaidhane, Santosh Gaihre, Nasrin Galehdar, Alberto L Garcia-Basteiro, Tushar Garg, Mesfin Damtew Gebrehiwot, Mathewos Alemu Gebremichael, Yibeltal Yismaw Gela, Belete Negese Belete Gemeda, Bradford D Gessner, Melaku Getachew, Asmare Getie, Seyyed-Hadi Ghamari, Mohammad Ghasemi Nour, Ahmad Ghashghaee, Ali Gholamrezanezhad, Abdolmajid Gholizadeh, Rakesh Ghosh, Sherief Ghozy, Pouya Goleij, Mohamad Golitaleb, Giuseppe Gorini, Alessandra C Goulart, Girma Garedew Goyomsa, Habtamu Alganeh Guadie, Zewdie Gudisa, Rashid Abdi Guled, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Alemu Guta, Parham Habibzadeh, Arvin Haj-Mirzaian, Rabih Halwani, Samer Hamidi, Md Abdul Hannan, Mehdi Harorani, Ahmed I Hasaballah, Hamidreza Hasani, Abbas M Hassan, Shokoufeh Hassani, Hossein Hassanian-Moghaddam, Hadi Hassankhani, Khezar Hayat, Behzad Heibati, Mohammad Heidari, Demisu Zenbaba Heyi, Kamal Hezam, Ramesh Holla, Sung Hwi Hong, Nobuyuki Horita, Mohammad-Salar Hosseini, Mehdi Hosseinzadeh, Mihaela Hostiuc, Mowafa Househ, Soodabeh Hoveidamanesh, Junjie Huang, Nawfal R Hussein, Ivo Iavicoli, Segun Emmanuel Ibitoye, Kevin S Ikuta, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Mustapha Immurana, Nahlah Elkudssiah Ismail, Masao Iwagami, Jalil Jaafari, Elham Jamshidi, Sung-In Jang, Amirreza Javadi Mamaghani, Tahereh Javaheri, Fatemeh Javanmardi, Javad Javidnia, Sathish Kumar Jayapal, Umesh Jayarajah, Shubha Jayaram, Alelign Tasew Jema, Wonjeong Jeong, Jost B Jonas, Nitin Joseph, Farahnaz Joukar, Jacek Jerzy Jozwiak, Vaishali K, Zubair Kabir, Salah Eddine Oussama Kacimi, Vidya Kadashetti, Laleh R Kalankesh, Rohollah Kalhor, Ashwin Kamath, Bhushan Dattatray Kamble, Himal Kandel, Tesfaye K Kanko, Ibraheem M Karaye, André Karch, Samad Karkhah, Bekalu Getnet Kassa, Patrick DMC Katoto, Harkiran Kaur, Rimple Jeet Kaur, Leila Keikavoosi-Arani, Mohammad Keykhaei, Yousef Saleh Khader, Himanshu Khajuria, Ejaz Ahmad Khan, Gulfaraz Khan, Imteyaz A Khan, Maseer Khan, Md Nuruzzaman Khan, Moien AB Khan, Yusra H Khan, Moawiah Mohammad Khatatbeh, Mina Khosravifar, Jagdish Khubchandani, Min Seo Kim, Ruth W Kimokoti, Adnan Kisa, Sezer Kisa, Niranjan Kissoon, Luke D Knibbs, Sonali Kochhar, Farzad Kompani, Hamid Reza Koohestani, Vladimir Andreevich Korshunov, Soewarta Kosen, Parvaiz A Koul, Ai Koyanagi, Kewal Krishan, Barthelemy Kuate Defo, G Anil Kumar, Om P Kurmi, Ambily Kuttikkattu, Dharmesh Kumar Lal, Judit Lám, Iván Landires, Caterina Ledda, Sang-woong Lee, Miriam Levi, Sonia Lewycka, Gang Liu, Wei Liu, Rakesh Lodha, László Lorenzovici, Mojgan Lotfi, Joana A Loureiro, Farzan Madadizadeh, Ata Mahmoodpoor, Razzagh Mahmoudi, Marzieh Mahmoudimanesh, Jamal Majidpoor, Alaa Makki, Elaheh Malakan Rad, Ahmad Azam Malik, Tauqeer Hussain Mallhi, Yosef Manla, Clara N Matei, Alexander G Mathioudakis, Richard James Maude, Entezar Mehrabi Nasab, Addisu Melese, Ziad A Memish, Oliver Mendoza-Cano, Alexios-Fotios A Mentis, Tuomo J Meretoja, Mehari Woldemariam Merid, Tomislav Mestrovic, Ana Carolina Micheletti Gomide Nogueira de Sá, Gelana Fekadu Worku Mijena, Le Huu Nhat Minh, Shabir Ahmad Mir, Reza Mirfakhraie, Seyyedmohammadsadeq Mirmoeeni, Agha Zeeshan Mirza, Moonis Mirza, Mohammad Mirza-Aghazadeh-Attari, Abay Sisay Misganaw, Awoke Temesgen Misganaw, Esmaeil Mohammadi, Mokhtar Mohammadi, Arif Mohammed, Shafiu Mohammed, Syam Mohan, Mohammad Mohseni, Nagabhishek Moka, Ali H Mokdad, Sara Momtazmanesh, Lorenzo Monasta, Md Moniruzzaman, Fateme Montazeri, Catrin E Moore, Abdolvahab Moradi, Lidia Morawska, Jonathan F Mosser, Ebrahim Mostafavi, Majid Motaghinejad, Haleh Mousavi Isfahani, Seyed Ali Mousavi-Aghdas, Sumaira Mubarik, Efrén Murillo-Zamora, Ghulam Mustafa, Sanjeev Nair, Tapas Sadasivan Nair, Houshang Najafi, Atta Abbas Naqvi, Sreenivas Narasimha Swamy, Zuhair S Natto, Biswa Prakash Nayak, Seyed Aria Nejadghaderi, Huy Van Nguyen Nguyen, Robina Khan Niazi, Antonio Tolentino Nogueira de Sá, Hasti Nouraei, Ali Nowroozi, Virginia Nuñez-Samudio, Chimezie Igwegbe Nzoputam, Ogochukwu Janet Nzoputam, Bogdan Oancea, Chimedsuren Ochir, Oluwakemi Ololade Odukoya, Hassan Okati-Aliabad, Akinkunmi Paul Okekunle, Osaretin Christabel Okonji, Andrew T Olagunju, Isaac Iyinoluwa Olufadewa, Ahmed Omar Bali, Emad Omer, Eyal Oren, Erika Ota, Nikita Otstavnov, Abderrahim Oulhaj, Mahesh P A, Jagadish Rao Padubidri, Keyvan Pakshir, Reza Pakzad, Tamás Palicz, Anamika Pandey, Suman Pant, Shahina Pardhan, Eun-Cheol Park, Eun-Kee Park, Fatemeh Pashazadeh Kan, Rajan Paudel, Shrikant Pawar, Minjin Peng, Gavin Pereira, Simone Perna, Navaraj Perumalsamy, Ionela-Roxana Petcu, David M Pigott, Zahra Zahid Piracha, Vivek Podder, Roman V Polibin, Maarten J Postma, Hamid Pourasghari, Naeimeh Pourtaheri, Mirza Muhammad Fahd Qadir, Mathieu Raad, Mohammad Rabiee, Navid Rabiee, Saber Raeghi, Alireza Rafiei, Fakher Rahim, Mehran Rahimi, Vafa Rahimi-Movaghar, Azizur Rahman, Md Obaidur Rahman, Mosiur Rahman, Muhammad Aziz Rahman, Amir Masoud Rahmani, Vahid Rahmanian, Pradhum Ram, Kiana Ramezanzadeh, Juwel Rana, Priyanga Ranasinghe, Usha Rani, Sowmya J Rao, Sina Rashedi, Mohammad-Mahdi Rashidi, Azad Rasul, Zubair Ahmed Ratan, David Laith Rawaf, Salman Rawaf, Reza Rawassizadeh, Mohammad Sadegh Razeghinia, Elrashdy Moustafa Mohamed Redwan, Marissa B Reitsma, Andre M N Renzaho, Mohsen Rezaeian, Abanoub Riad, Reza Rikhtegar, Jefferson Antonio Buendia Rodriguez, Emma L B Rogowski, Luca Ronfani, Kristina E Rudd, Basema Saddik, Erfan Sadeghi, Umar Saeed, Azam Safary, Sher Zaman Safi, Maryam Sahebazzamani, Amirhossein Sahebkar, Sateesh Sakhamuri, Sana Salehi, Muhammad Salman, Hossein Samadi Kafil, Abdallah M Samy, Milena M Santric-Milicevic, Bruno Piassi Sao Jose, Maryam Sarkhosh, Brijesh Sathian, Monika Sawhney, Ganesh Kumar Saya, Abdul-Aziz Seidu, Allen Seylani, Amira A Shaheen, Masood Ali Shaikh, Elaheh Shaker, Hina Shamshad, Mequannent Melaku Sharew, Asaad Sharhani, Azam Sharifi, Purva Sharma, Ali Sheidaei, Suchitra M Shenoy, Jeevan K Shetty, Damtew Solomon Shiferaw, Mika Shigematsu, Jae Il Shin, Hesamaddin Shirzad-Aski, K M Shivakumar, Siddharudha Shivalli, Parnian Shobeiri, Wudneh Simegn, Colin R Simpson, Harpreet Singh, Jasvinder A Singh, Paramdeep Singh, Samarjeet Singh Siwal, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Mohammad Sadegh Soltani-Zangbar, Suhang Song, Yimeng Song, Prashant Sood, Chandrashekhar T Sreeramareddy, Paschalis Steiropoulos, Muhammad Suleman, Seyed-Amir Tabatabaeizadeh, Alireza Tahamtan, Majid Taheri, Moslem Taheri Soodejani, Elahe Taki, Iman M Talaat, Mircea Tampa, Sarmila Tandukar, Nathan Y Tat, Vivian Y Tat, Yibekal Manaye Tefera, Gebremaryam Temesgen, Mohamad-Hani Temsah, Azene Tesfaye, Degefa Gomora Tesfaye, Belay Tessema, Rekha Thapar, Jansje Henny Vera Ticoalu, Amir Tiyuri, Imad I Tleyjeh, Munkhsaikhan Togtmol, Marcos Roberto Tovani-Palone, Derara Girma Tufa, Irfan Ullah, Era Upadhyay, Sahel Valadan Tahbaz, Pascual R Valdez, Rohollah Valizadeh, Constantine Vardavas, Tommi Juhani Vasankari, Bay Vo, Linh Gia Vu, Birhanu Wagaye, Yasir Waheed, Yu Wang, Abdul Waris, T Eoin West, Nuwan Darshana Wickramasinghe, Xiaoyue Xu, Sajad Yaghoubi, Gahin Abdulraheem Tayib Yahya, Seyed Hossein Yahyazadeh Jabbari, Dong Keon Yon, Naohiro Yonemoto, Burhan Abdullah Zaman, Alireza Zandifar, Moein Zangiabadian, Heather J Zar, Iman Zare, Zahra Zareshahrabadi, Armin Zarrintan, Mikhail Sergeevich Zastrozhin, Wu Zeng, Mengxi Zhang, Zhi-Jiang Zhang, Chenwen Zhong, Mohammad Zoladl, Alimuddin Zumla, Stephen S Lim, Theo Vos, Mohsen Naghavi, Michael Brauer, Simon I Hay, Christopher J L Murray, Kyu, H. H., Vongpradith, A., Sirota, S. B., Novotney, A., Troeger, C. E., Doxey, M. C., Bender, R. G., Ledesma, J. R., Biehl, M. H., Albertson, S. B., Frostad, J. J., Burkart, K., Bennitt, F. B., Zhao, J. T., Gardner, W. M., Hagins, H., Bryazka, D., Dominguez, R. -M. V., Abate, S. M., Abdelmasseh, M., Abdoli, A., Abdoli, G., Abedi, A., Abedi, V., Abegaz, T. M., Abidi, H., Aboagye, R. G., Abolhassani, H., Abtew, Y. D., Abubaker Ali, H., Abu-Gharbieh, E., Abu-Zaid, A., Adamu, K., Addo, I. Y., Adegboye, O. A., Adnan, M., Adnani, Q. E. S., Afzal, M. S., Afzal, S., Ahinkorah, B. O., Ahmad, A., Ahmad, A. R., Ahmad, S., Ahmadi, A., Ahmadi, S., Ahmed, H., Ahmed, J. Q., Ahmed Rashid, T., Akbarzadeh-Khiavi, M., Al Hamad, H., Albano, L., Aldeyab, M. A., Alemu, B. M., Alene, K. A., Algammal, A. M., Alhalaiqa, F. A. N., Alhassan, R. K., Ali, B. A., Ali, L., Ali, M. M., Ali, S. S., Alimohamadi, Y., Alipour, V., Al-Jumaily, A., Aljunid, S. M., Almustanyir, S., Al-Raddadi, R. M., Al-Rifai, R. H. H., Alryalat, S. A. S., Alvis-Guzman, N., Alvis-Zakzuk, N. J., Ameyaw, E. K., Aminian Dehkordi, J. J., Amuasi, J. H., Amugsi, D. A., Anbesu, E. W., Ansar, A., Anyasodor, A. E., Arabloo, J., Areda, D., Argaw, A. M., Argaw, Z. G., Arulappan, J., Aruleba, R. T., Asemahagn, M. A., Athari, S. S., Atlaw, D., Attia, E. F., Attia, S., Aujayeb, A., Awoke, T., Ayana, T. M., Ayanore, M. A., Azadnajafabad, S., Azangou-Khyavy, M., Azari, S., Azari Jafari, A., Badar, M., Badiye, A. D., Baghcheghi, N., Bagherieh, S., Baig, A. A., Banach, M., Banerjee, I., Bardhan, M., Barone-Adesi, F., Barqawi, H. J., Barrow, A., Bashiri, A., Bassat, Q., Batiha, A. -M. M., Belachew, A. B., Belete, M. A., Belgaumi, U. I., Bhagavathula, A. S., Bhardwaj, N., Bhardwaj, P., Bhatt, P., Bhojaraja, V. S., Bhutta, Z. A., Bhuyan, S. S., Bijani, A., Bitaraf, S., Bodicha, B. B. A., Briko, N. I., Buonsenso, D., Butt, M. H., Cai, J., Camargos, P., Camera, L. A., Chakraborty, P. A., Chanie, M. G., Charan, J., Chattu, V. K., Ching, P. R., Choi, S., Chong, Y. Y., Choudhari, S. G., Chowdhury, E. K., Christopher, D. J., Chu, D. -T., Cobb, N. L., Cohen, A. J., Cruz-Martins, N., Dadras, O., Dagnaw, F. T., Dai, X., Dandona, L., Dandona, R., Dao, A. T. M., Debela, S. A., Demisse, B., Demisse, F. W., Demissie, S., Dereje, D., Desai, H. D., Desta, A. A., Desye, B., Dhingra, S., Diao, N., Diaz, D., Digesa, L. E., Doan, L. P., Dodangeh, M., Dongarwar, D., Dorostkar, F., dos Santos, W. M., Dsouza, H. L., Dubljanin, E., Durojaiye, O. C., Edinur, H. A., Ehsani-Chimeh, E., Eini, E., Ekholuenetale, M., Ekundayo, T. C., El Desouky, E. D., El Sayed, I., El Sayed Zaki, M., Elhadi, M., Elkhapery, A. M. R., Emami, A., Engelbert Bain, L., Erkhembayar, R., Etaee, F., Ezati Asar, M., Fagbamigbe, A. F., Falahi, S., Fallahzadeh, A., Faraj, A., Faraon, E. J. A., Fatehizadeh, A., Ferrara, P., Ferrari, A. A., Fetensa, G., Fischer, F., Flavel, J., Foroutan, M., Gaal, P. A., Gaidhane, A. M., Gaihre, S., Galehdar, N., Garcia-Basteiro, A. L., Garg, T., Gebrehiwot, M. D., Gebremichael, M. A., Gela, Y. Y., Gemeda, B. N. B., Gessner, B. D., Getachew, M., Getie, A., Ghamari, S. -H., Ghasemi Nour, M., Ghashghaee, A., Gholamrezanezhad, A., Gholizadeh, A., Ghosh, R., Ghozy, S., Goleij, P., Golitaleb, M., Gorini, G., Goulart, A. C., Goyomsa, G. G., Guadie, H. A., Gudisa, Z., Guled, R. A., Gupta, S., Gupta, V. B., Gupta, V. K., Guta, A., Habibzadeh, P., Haj-Mirzaian, A., Halwani, R., Hamidi, S., Hannan, M. A., Harorani, M., Hasaballah, A. I., Hasani, H., Hassan, A. M., Hassani, S., Hassanian-Moghaddam, H., Hassankhani, H., Hayat, K., Heibati, B., Heidari, M., Heyi, D. Z., Hezam, K., Holla, R., Hong, S. H., Horita, N., Hosseini, M. -S., Hosseinzadeh, M., Hostiuc, M., Househ, M., Hoveidamanesh, S., Huang, J., Hussein, N. R., Iavicoli, I., Ibitoye, S. E., Ikuta, K. S., Ilesanmi, O. S., Ilic, I. M., Ilic, M. D., Immurana, M., Ismail, N. E., Iwagami, M., Jaafari, J., Jamshidi, E., Jang, S. -I., Javadi Mamaghani, A., Javaheri, T., Javanmardi, F., Javidnia, J., Jayapal, S. K., Jayarajah, U., Jayaram, S., Jema, A. T., Jeong, W., Jonas, J. B., Joseph, N., Joukar, F., Jozwiak, J. J., K, V., Kabir, Z., Kacimi, S. E. O., Kadashetti, V., Kalankesh, L. R., Kalhor, R., Kamath, A., Kamble, B. D., Kandel, H., Kanko, T. K., Karaye, I. M., Karch, A., Karkhah, S., Kassa, B. G., Katoto, P. D., Kaur, H., Kaur, R. J., Keikavoosi-Arani, L., Keykhaei, M., Khader, Y. S., Khajuria, H., Khan, E. A., Khan, G., Khan, I. A., Khan, M., Khan, M. N., Khan, M. A., Khan, Y. H., Khatatbeh, M. M., Khosravifar, M., Khubchandani, J., Kim, M. S., Kimokoti, R. W., Kisa, A., Kisa, S., Kissoon, N., Knibbs, L. D., Kochhar, S., Kompani, F., Koohestani, H. R., Korshunov, V. A., Kosen, S., Koul, P. A., Koyanagi, A., Krishan, K., Kuate Defo, B., Kumar, G. A., Kurmi, O. P., Kuttikkattu, A., Lal, D. K., Lam, J., Landires, I., Ledda, C., Lee, S. -W., Levi, M., Lewycka, S., Liu, G., Liu, W., Lodha, R., Lorenzovici, L., Lotfi, M., Loureiro, J. A., Madadizadeh, F., Mahmoodpoor, A., Mahmoudi, R., Mahmoudimanesh, M., Majidpoor, J., Makki, A., Malakan Rad, E., Malik, A. A., Mallhi, T. H., Manla, Y., Matei, C. N., Mathioudakis, A. G., Maude, R. J., Mehrabi Nasab, E., Melese, A., Memish, Z. A., Mendoza-Cano, O., Mentis, A. -F. A., Meretoja, T. J., Merid, M. W., Mestrovic, T., Micheletti Gomide Nogueira de Sa, A. C., Mijena, G. F. W., Minh, L. H. N., Mir, S. A., Mirfakhraie, R., Mirmoeeni, S., Mirza, A. Z., Mirza, M., Mirza-Aghazadeh-Attari, M., Misganaw, A. S., Misganaw, A. T., Mohammadi, E., Mohammadi, M., Mohammed, A., Mohammed, S., Mohan, S., Mohseni, M., Moka, N., Mokdad, A. H., Momtazmanesh, S., Monasta, L., Moniruzzaman, M., Montazeri, F., Moore, C. E., Moradi, A., Morawska, L., Mosser, J. F., Mostafavi, E., Motaghinejad, M., Mousavi Isfahani, H., Mousavi-Aghdas, S. A., Mubarik, S., Murillo-Zamora, E., Mustafa, G., Nair, S., Nair, T. S., Najafi, H., Naqvi, A. A., Narasimha Swamy, S., Natto, Z. S., Nayak, B. P., Nejadghaderi, S. A., Nguyen, H. V. N., Niazi, R. K., Nogueira de Sa, A. T., Nouraei, H., Nowroozi, A., Nunez-Samudio, V., Nzoputam, C. I., Nzoputam, O. J., Oancea, B., Ochir, C., Odukoya, O. O., Okati-Aliabad, H., Okekunle, A. P., Okonji, O. C., Olagunju, A. T., Olufadewa, I. I., Omar Bali, A., Omer, E., Oren, E., Ota, E., Otstavnov, N., Oulhaj, A., P A, M., Padubidri, J. R., Pakshir, K., Pakzad, R., Palicz, T., Pandey, A., Pant, S., Pardhan, S., Park, E. -C., Park, E. -K., Pashazadeh Kan, F., Paudel, R., Pawar, S., Peng, M., Pereira, G., Perna, S., Perumalsamy, N., Petcu, I. -R., Pigott, D. M., Piracha, Z. Z., Podder, V., Polibin, R. V., Postma, M. J., Pourasghari, H., Pourtaheri, N., Qadir, M. M. F., Raad, M., Rabiee, M., Rabiee, N., Raeghi, S., Rafiei, A., Rahim, F., Rahimi, M., Rahimi-Movaghar, V., Rahman, A., Rahman, M. O., Rahman, M., Rahman, M. A., Rahmani, A. M., Rahmanian, V., Ram, P., Ramezanzadeh, K., Rana, J., Ranasinghe, P., Rani, U., Rao, S. J., Rashedi, S., Rashidi, M. -M., Rasul, A., Ratan, Z. A., Rawaf, D. L., Rawaf, S., Rawassizadeh, R., Razeghinia, M. S., Redwan, E. M. M., Reitsma, M. B., Renzaho, A. M. N., Rezaeian, M., Riad, A., Rikhtegar, R., Rodriguez, J. A. B., Rogowski, E. L. B., Ronfani, L., Rudd, K. E., Saddik, B., Sadeghi, E., Saeed, U., Safary, A., Safi, S. Z., Sahebazzamani, M., Sahebkar, A., Sakhamuri, S., Salehi, S., Salman, M., Samadi Kafil, H., Samy, A. M., Santric-Milicevic, M. M., Sao Jose, B. P., Sarkhosh, M., Sathian, B., Sawhney, M., Saya, G. K., Seidu, A. -A., Seylani, A., Shaheen, A. A., Shaikh, M. A., Shaker, E., Shamshad, H., Sharew, M. M., Sharhani, A., Sharifi, A., Sharma, P., Sheidaei, A., Shenoy, S. M., Shetty, J. K., Shiferaw, D. S., Shigematsu, M., Shin, J. I., Shirzad-Aski, H., Shivakumar, K. M., Shivalli, S., Shobeiri, P., Simegn, W., Simpson, C. R., Singh, H., Singh, J. A., Singh, P., Siwal, S. S., Skryabin, V. Y., Skryabina, A. A., Soltani-Zangbar, M. S., Song, S., Song, Y., Sood, P., Sreeramareddy, C. T., Steiropoulos, P., Suleman, M., Tabatabaeizadeh, S. -A., Tahamtan, A., Taheri, M., Taheri Soodejani, M., Taki, E., Talaat, I. M., Tampa, M., Tandukar, S., Tat, N. Y., Tat, V. Y., Tefera, Y. M., Temesgen, G., Temsah, M. -H., Tesfaye, A., Tesfaye, D. G., Tessema, B., Thapar, R., Ticoalu, J. H. V., Tiyuri, A., Tleyjeh, I. I., Togtmol, M., Tovani-Palone, M. R., Tufa, D. G., Ullah, I., Upadhyay, E., Valadan Tahbaz, S., Valdez, P. R., Valizadeh, R., Vardavas, C., Vasankari, T. J., Vo, B., Vu, L. G., Wagaye, B., Waheed, Y., Wang, Y., Waris, A., West, T. E., Wickramasinghe, N. D., Xu, X., Yaghoubi, S., Yahya, G. A. T., Yahyazadeh Jabbari, S. H., Yon, D. K., Yonemoto, N., Zaman, B. A., Zandifar, A., Zangiabadian, M., Zar, H. J., Zare, I., Zareshahrabadi, Z., Zarrintan, A., Zastrozhin, M. S., Zeng, W., Zhang, M., Zhang, Z. -J., Zhong, C., Zoladl, M., Zumla, A., Lim, S. S., Vos, T., Naghavi, M., Brauer, M., Hay, S. I., Murray, C. J. L., University of St Andrews. School of Medicine, University of St Andrews. Population and Behavioural Science Division, Tampere University, Health Sciences, Clinical Medicine, Kyu, H, Vongpradith, A, Sirota, S, Novotney, A, Troeger, C, Doxey, M, Bender, R, Ledesma, J, Biehl, M, Albertson, S, Frostad, J, Burkart, K, Bennitt, F, Zhao, J, Gardner, W, Hagins, H, Bryazka, D, Dominguez, R, Abate, S, Abdelmasseh, M, Abdoli, A, Abdoli, G, Abedi, A, Abedi, V, Abegaz, T, Abidi, H, Aboagye, R, Abolhassani, H, Abtew, Y, Abubaker Ali, H, Abu-Gharbieh, E, Abu-Zaid, A, Adamu, K, Addo, I, Adegboye, O, Adnan, M, Adnani, Q, Afzal, M, Afzal, S, Ahinkorah, B, Ahmad, A, Ahmad, S, Ahmadi, A, Ahmadi, S, Ahmed, H, Ahmed, J, Ahmed Rashid, T, Akbarzadeh-Khiavi, M, Al Hamad, H, Albano, L, Aldeyab, M, Alemu, B, Alene, K, Algammal, A, Alhalaiqa, F, Alhassan, R, Ali, B, Ali, L, Ali, M, Ali, S, Alimohamadi, Y, Alipour, V, Al-Jumaily, A, Aljunid, S, Almustanyir, S, Al-Raddadi, R, Al-Rifai, R, Alryalat, S, Alvis-Guzman, N, Alvis-Zakzuk, N, Ameyaw, E, Aminian Dehkordi, J, Amuasi, J, Amugsi, D, Anbesu, E, Ansar, A, Anyasodor, A, Arabloo, J, Areda, D, Argaw, A, Argaw, Z, Arulappan, J, Aruleba, R, Asemahagn, M, Athari, S, Atlaw, D, Attia, E, Attia, S, Aujayeb, A, Awoke, T, Ayana, T, Ayanore, M, Azadnajafabad, S, Azangou-Khyavy, M, Azari, S, Azari Jafari, A, Badar, M, Badiye, A, Baghcheghi, N, Bagherieh, S, Baig, A, Banach, M, Banerjee, I, Bardhan, M, Barone-Adesi, F, Barqawi, H, Barrow, A, Bashiri, A, Bassat, Q, Batiha, A, Belachew, A, Belete, M, Belgaumi, U, Bhagavathula, A, Bhardwaj, N, Bhardwaj, P, Bhatt, P, Bhojaraja, V, Bhutta, Z, Bhuyan, S, Bijani, A, Bitaraf, S, Bodicha, B, Briko, N, Buonsenso, D, Butt, M, Cai, J, Camargos, P, Camera, L, Chakraborty, P, Chanie, M, Charan, J, Chattu, V, Ching, P, Choi, S, Chong, Y, Choudhari, S, Chowdhury, E, Christopher, D, Chu, D, Cobb, N, Cohen, A, Cruz-Martins, N, Dadras, O, Dagnaw, F, Dai, X, Dandona, L, Dandona, R, Dao, A, Debela, S, Demisse, B, Demisse, F, Demissie, S, Dereje, D, Desai, H, Desta, A, Desye, B, Dhingra, S, Diao, N, Diaz, D, Digesa, L, Doan, L, Dodangeh, M, Dongarwar, D, Dorostkar, F, dos Santos, W, Dsouza, H, Dubljanin, E, Durojaiye, O, Edinur, H, Ehsani-Chimeh, E, Eini, E, Ekholuenetale, M, Ekundayo, T, El Desouky, E, El Sayed, I, El Sayed Zaki, M, Elhadi, M, Elkhapery, A, Emami, A, Engelbert Bain, L, Erkhembayar, R, Etaee, F, Ezati Asar, M, Fagbamigbe, A, Falahi, S, Fallahzadeh, A, Faraj, A, Faraon, E, Fatehizadeh, A, Ferrara, P, Ferrari, A, Fetensa, G, Fischer, F, Flavel, J, Foroutan, M, Gaal, P, Gaidhane, A, Gaihre, S, Galehdar, N, Garcia-Basteiro, A, Garg, T, Gebrehiwot, M, Gebremichael, M, Gela, Y, Gemeda, B, Gessner, B, Getachew, M, Getie, A, Ghamari, S, Ghasemi Nour, M, Ghashghaee, A, Gholamrezanezhad, A, Gholizadeh, A, Ghosh, R, Ghozy, S, Goleij, P, Golitaleb, M, Gorini, G, Goulart, A, Goyomsa, G, Guadie, H, Gudisa, Z, Guled, R, Gupta, S, Gupta, V, Guta, A, Habibzadeh, P, Haj-Mirzaian, A, Halwani, R, Hamidi, S, Hannan, M, Harorani, M, Hasaballah, A, Hasani, H, Hassan, A, Hassani, S, Hassanian-Moghaddam, H, Hassankhani, H, Hayat, K, Heibati, B, Heidari, M, Heyi, D, Hezam, K, Holla, R, Hong, S, Horita, N, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Househ, M, Hoveidamanesh, S, Huang, J, Hussein, N, Iavicoli, I, Ibitoye, S, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Immurana, M, Ismail, N, Iwagami, M, Jaafari, J, Jamshidi, E, Jang, S, Javadi Mamaghani, A, Javaheri, T, Javanmardi, F, Javidnia, J, Jayapal, S, Jayarajah, U, Jayaram, S, Jema, A, Jeong, W, Jonas, J, Joseph, N, Joukar, F, Jozwiak, J, K, V, Kabir, Z, Kacimi, S, Kadashetti, V, Kalankesh, L, Kalhor, R, Kamath, A, Kamble, B, Kandel, H, Kanko, T, Karaye, I, Karch, A, Karkhah, S, Kassa, B, Katoto, P, Kaur, H, Kaur, R, Keikavoosi-Arani, L, Keykhaei, M, Khader, Y, Khajuria, H, Khan, E, Khan, G, Khan, I, Khan, M, Khan, Y, Khatatbeh, M, Khosravifar, M, Khubchandani, J, Kim, M, Kimokoti, R, Kisa, A, Kisa, S, Kissoon, N, Knibbs, L, Kochhar, S, Kompani, F, Koohestani, H, Korshunov, V, Kosen, S, Koul, P, Koyanagi, A, Krishan, K, Kuate Defo, B, Kumar, G, Kurmi, O, Kuttikkattu, A, Lal, D, Lam, J, Landires, I, Ledda, C, Lee, S, Levi, M, Lewycka, S, Liu, G, Liu, W, Lodha, R, Lorenzovici, L, Lotfi, M, Loureiro, J, Madadizadeh, F, Mahmoodpoor, A, Mahmoudi, R, Mahmoudimanesh, M, Majidpoor, J, Makki, A, Malakan Rad, E, Malik, A, Mallhi, T, Manla, Y, Matei, C, Mathioudakis, A, Maude, R, Mehrabi Nasab, E, Melese, A, Memish, Z, Mendoza-Cano, O, Mentis, A, Meretoja, T, Merid, M, Mestrovic, T, Micheletti Gomide Nogueira de Sa, A, Mijena, G, Minh, L, Mir, S, Mirfakhraie, R, Mirmoeeni, S, Mirza, A, Mirza, M, Mirza-Aghazadeh-Attari, M, Misganaw, A, Mohammadi, E, Mohammadi, M, Mohammed, A, Mohammed, S, Mohan, S, Mohseni, M, Moka, N, Mokdad, A, Momtazmanesh, S, Monasta, L, Moniruzzaman, M, Montazeri, F, Moore, C, Moradi, A, Morawska, L, Mosser, J, Mostafavi, E, Motaghinejad, M, Mousavi Isfahani, H, Mousavi-Aghdas, S, Mubarik, S, Murillo-Zamora, E, Mustafa, G, Nair, S, Nair, T, Najafi, H, Naqvi, A, Narasimha Swamy, S, Natto, Z, Nayak, B, Nejadghaderi, S, Nguyen, H, Niazi, R, Nogueira de Sa, A, Nouraei, H, Nowroozi, A, Nunez-Samudio, V, Nzoputam, C, Nzoputam, O, Oancea, B, Ochir, C, Odukoya, O, Okati-Aliabad, H, Okekunle, A, Okonji, O, Olagunju, A, Olufadewa, I, Omar Bali, A, Omer, E, Oren, E, Ota, E, Otstavnov, N, Oulhaj, A, P A, M, Padubidri, J, Pakshir, K, Pakzad, R, Palicz, T, Pandey, A, Pant, S, Pardhan, S, Park, E, Pashazadeh Kan, F, Paudel, R, Pawar, S, Peng, M, Pereira, G, Perna, S, Perumalsamy, N, Petcu, I, Pigott, D, Piracha, Z, Podder, V, Polibin, R, Postma, M, Pourasghari, H, Pourtaheri, N, Qadir, M, Raad, M, Rabiee, M, Rabiee, N, Raeghi, S, Rafiei, A, Rahim, F, Rahimi, M, Rahimi-Movaghar, V, Rahman, A, Rahman, M, Rahmani, A, Rahmanian, V, Ram, P, Ramezanzadeh, K, Rana, J, Ranasinghe, P, Rani, U, Rao, S, Rashedi, S, Rashidi, M, Rasul, A, Ratan, Z, Rawaf, D, Rawaf, S, Rawassizadeh, R, Razeghinia, M, Redwan, E, Reitsma, M, Renzaho, A, Rezaeian, M, Riad, A, Rikhtegar, R, Rodriguez, J, Rogowski, E, Ronfani, L, Rudd, K, Saddik, B, Sadeghi, E, Saeed, U, Safary, A, Safi, S, Sahebazzamani, M, Sahebkar, A, Sakhamuri, S, Salehi, S, Salman, M, Samadi Kafil, H, Samy, A, Santric-Milicevic, M, Sao Jose, B, Sarkhosh, M, Sathian, B, Sawhney, M, Saya, G, Seidu, A, Seylani, A, Shaheen, A, Shaikh, M, Shaker, E, Shamshad, H, Sharew, M, Sharhani, A, Sharifi, A, Sharma, P, Sheidaei, A, Shenoy, S, Shetty, J, Shiferaw, D, Shigematsu, M, Shin, J, Shirzad-Aski, H, Shivakumar, K, Shivalli, S, Shobeiri, P, Simegn, W, Simpson, C, Singh, H, Singh, J, Singh, P, Siwal, S, Skryabin, V, Skryabina, A, Soltani-Zangbar, M, Song, S, Song, Y, Sood, P, Sreeramareddy, C, Steiropoulos, P, Suleman, M, Tabatabaeizadeh, S, Tahamtan, A, Taheri, M, Taheri Soodejani, M, Taki, E, Talaat, I, Tampa, M, Tandukar, S, Tat, N, Tat, V, Tefera, Y, Temesgen, G, Temsah, M, Tesfaye, A, Tesfaye, D, Tessema, B, Thapar, R, Ticoalu, J, Tiyuri, A, Tleyjeh, I, Togtmol, M, Tovani-Palone, M, Tufa, D, Ullah, I, Upadhyay, E, Valadan Tahbaz, S, Valdez, P, Valizadeh, R, Vardavas, C, Vasankari, T, Vo, B, Vu, L, Wagaye, B, Waheed, Y, Wang, Y, Waris, A, West, T, Wickramasinghe, N, Xu, X, Yaghoubi, S, Yahya, G, Yahyazadeh Jabbari, S, Yon, D, Yonemoto, N, Zaman, B, Zandifar, A, Zangiabadian, M, Zar, H, Zare, I, Zareshahrabadi, Z, Zarrintan, A, Zastrozhin, M, Zeng, W, Zhang, M, Zhang, Z, Zhong, C, Zoladl, M, Zumla, A, Lim, S, Vos, T, Naghavi, M, Brauer, M, Hay, S, Murray, C, HUS Comprehensive Cancer Center, and Department of Oncology
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Adult ,Male ,Global Health ,Time ,Global Burden of Disease ,SDG 3 - Good Health and Well-being ,Risk Factors ,RA0421 ,RA0421 Public health. Hygiene. Preventive Medicine ,Humans ,Ambient air-quality ,Child ,Respiratory Tract Infections ,Aged ,Aged, 80 and over ,MCC ,Sex Characteristics ,Malnutrition ,Pyridinolcarbamate ,Bayes Theorem ,3rd-DAS ,3142 Public health care science, environmental and occupational health ,Infectious Diseases ,3121 General medicine, internal medicine and other clinical medicine ,Child, Preschool ,Female ,Particulate Matter ,Quality-Adjusted Life Years ,Covid-19 ,LRI - Abstract
Funding: Bill & Melinda Gates Foundation. Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories. Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors. Findings: Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). The leading risk factors for LRI mortality varied across age groups and sex. More than half of global LRI deaths in children younger than 5 years were attributable to child wasting (population attributable fraction [PAF] 53·0% [95% UI 37·7–61·8] in males and 56·4% [40·7–65·1] in females), and more than a quarter of LRI deaths among those aged 5–14 years were attributable to household air pollution (PAF 26·0% [95% UI 16·6–35·5] for males and PAF 25·8% [16·3–35·4] for females). PAFs of male LRI deaths attributed to smoking were 20·4% (95% UI 15·4–25·2) in those aged 15–49 years, 30·5% (24·1–36·9) in those aged 50–69 years, and 21·9% (16·8–27·3) in those aged 70 years and older. PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. For females aged 70 years and older, the leading risk factor, ambient particulate matter, was responsible for 11·7% (95% UI 8·2–15·8) of LRI deaths. Interpretation: The patterns and progress in reducing the burden of LRIs and key risk factors for mortality varied across age groups and sexes. The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. Similar interventions for other age groups could contribute to the achievement of multiple Sustainable Development Goals targets, including promoting wellbeing at all ages and reducing health inequalities. Interventions, including addressing risk factors such as child wasting, smoking, ambient particulate matter pollution, and household air pollution, would prevent deaths and reduce health disparities. Publisher PDF
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- 2022
10. Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019
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Paulson, K. R., Kamath, A. M., Alam, T., Bienhoff, K., Abady, G. G., Abbas, J., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., Abd-Elsalam, S. M., Abdoli, A., Abedi, A., Abolhassani, H., Abreu, L. G., Abu-Gharbieh, E., Abu-Rmeileh, N. M. E., Abushouk, A. I., Adamu, A. L., Adebayo, O. M., Adegbosin, A. E., Adekanmbi, V., Adetokunboh, O. O., Adeyinka, D. A., Adsuar, J. C., Afshari, K., Aghaali, M., Agudelo-Botero, M., Ahinkorah, B. O., Ahmad, T., Ahmadi, K., Ahmed, M. B., Aji, B., Akalu, Y., Akinyemi, O. O., Aklilu, A., Al-Aly, Z., Alam, K., Alanezi, F. M., Alanzi, T. M., Alcalde-Rabanal, J. E., Al-Eyadhy, A., Ali, T., Alicandro, G., Alif, S. M., Alipour, V., Alizade, H., Aljunid, S. M., Almasi-Hashiani, A., Almasri, N. A., Al-Mekhlafi, H. M., Alonso, J., Al-Raddadi, R. M., Altirkawi, K. A., Alumran, A. K., Alvis-Guzman, N., Alvis-Zakzuk, N. J., Ameyaw, E. K., Amini, S., Amini-Rarani, M., Amit, A. M. L., Amugsi, D. A., Ancuceanu, R., Anderlini, D., Andrei, C. L., Ansari, F., Ansari-Moghaddam, A., Antonio, C. A. T., Antriyandarti, E., Anvari, D., Anwer, R., Aqeel, M., Arabloo, J., Arab-Zozani, M., Aripov, T., Arnlov, J., Artanti, K. D., Arzani, A., Asaad, M., Asadi-Aliabadi, M., Asadi-Pooya, Ali A, Jafarabadi, M. A., Athari, S. S., Athari, S. M., Atnafu, D. D., Atreya, A., Atteraya, M. S., Ausloos, M., Awan, A. T., Quintanilla, B. P. A., Ayano, G., Ayanore, M. A., Aynalem, Y. A., Azari, S., Azarian, G., Azene, Z. N., Darshan, BB, Babaee, E., Badiye, A. D., Baig, A. A., Banach, M., Banik, P. C., Barker-Collo, S. L., Barqawi, H. J., Bassat, Q., Basu, S., Baune, B.T., Bayati, M., Bedi, N., Beghi, E., Beghi, M., Bell, M. L., Bendak, S., Bennett, D. A., Bensenor, I. M., Berhe, K., Berman, A. E., Bezabih, Y. M., Bhagavathula, A. S., Bhandari, D., Bhardwaj, N., Bhardwaj, P., Bhattacharyya, K., Bhattarai, S., Bhutta, Z. A., Bikbov, B., Biondi, A., Birihane, B. M., Biswas, R. K., Bohlouli, S., Bragazzi, N. L., Breusov, A. V., Brunoni, A. R., Burkart, K., Nagaraja, S. B., Busse, R., Butt, Z. A., dos Santos, F. L. C., Cahuana-Hurtado, L., Camargos, P., Camera, L. A., Cardenas, R., Carreras, G., Carrero, J. J., Carvalho, F., Castaldelli-Maia, J. M., Castaneda-Orjuela, C. A., Castelpietra, G., Cerin, E., Chang, J-C., Chanie, W. F., Charan, J., Chatterjee, S., Chattu, S. K., Chattu, V. K., Chaturvedi, S., Chen, S., Cho, D. Y., Choi, J-Y. J., Chu, D-T., Ciobanu, L. G., Cirillo, M., Conde, J., Costa, V. M., Couto, R. A. S., Dachew, B. A., Dahlawi, S. M. A., Dai, H., Dai, X., Dandona, L., Dandona, R., Daneshpajouhnejad, P., Darmstadt, G. L., Das, J. K., Davila-Cervantes, C. A., Davis, A. C., Davletov, K., De la Hoz, F. P., De Leo, D., Deeba, F., Denova-Gutierrez, E., Dervenis, N., Desalew, A., Deuba, K., Dey, S., Dharmaratne, S. D., Dhingra, S., Dhungana, G. P., da Silva, D. D., Diaz, D., Dorostkar, F., Doshmangir, L., Dubljanin, E., Duraes, A. R., Eagan, A. W., Edinur, H. A., Efendi, F., Eftekharzadeh, S., El Sayed, I., El Tantawi, M., Elbarazi, I., Elgendy, I. Y., El-Jaafary, S. I., Emami, A., Enany, S., Eyawo, O., Ezzikouri, S., Faris, P. S., Farzadfar, F., Fattahi, N., Fauk, N. K., Fazlzadeh, M., Feigin, V. L., Ferede, T. Y., Fereshtehnejad, S-M., Fernandes, E., Ferrara, P., Filip, I., Fischer, F., Fisher, J. L., Foigt, N. A., Folayan, M. O., Foroutan, M., Franklin, R. C., Freitas, M., Friedman, S. D., Fukumoto, T., Gad, M. M., Gaidhane, A. M., Gaidhane, S., Gaihre, S., Gallus, S., Garcia-Basteiro, A. L., Garcia-Gordillo, M., Gardner, W. M., Fonseca, M. G., Gebremedhin, K. B., Getacher, L., Ghashghaee, A., Gholamian, A., Gilani, S.A., Gill, T. K., Giussani, G., Gnedovskaya, E. V., Godinho, M. A., Goel, A., Golechha, M., Gona, P. N., Gopalani, S. V., Goudarzi, H., Grivna, M., Gugnani, H. C., Guido, D., Guimaraes, R. A., Das Gupta, R., Gupta, R., Hafezi-Nejad, N., Haider, M. R., Haj-Mirzaian, A., Hamidi, S., Hanif, A., Hankey, G. J., Hargono, A., Hasaballah, A. I., Hasan, M. M., Hasan, S. S., Hassan, A., Hassanipour, S., Hassankhani, H., Havmoeller, R. J., Hayat, K., Heidari-Soureshjani, R., Henry, N. J., Herteliu, C., Hole, M. K., Holla, R., Hossain, N., Hosseini, M., Hosseinzadeh, M., Hostiuc, M., Hostiuc, S., Househ, M., Huang, J., Humayun, A., Hwang, B-F., Iavicoli, I., Ibitoye, S. E., Ikuta, K. S., Ilesanmi, O. St., Ilic, I.M., Ilic, M. D., Inamdar, S., Inbaraj, L. R., Iqbal, K., Iqbal, U., Islam, M. M., Islam, S. M. S., Iso, H., Iwagami, M., Iwu, C. C. D., Jaafari, J., Jacobsen, K. H., Jagnoor, J., Jain, V., Janodia, M. D., Javaheri, T., Javanmardi, F., Jayaram, S., Jayatilleke, A. U., Jenabi, E., Jha, R. P., Ji, J. S., John, O., Jonas, J. B., Joo, T., Joseph, N., Joukar, F., Jozwiak, J.J., Jurisson, M., Kabir, A., Kabir, Z., Kalankesh, L. R., Kamyari, N., Kanchan, T., Kapoor, N., Matin, B. K., Karch, A., Karimi, S. E., Kassahun, G., Kayode, G. A., Karyani, A. K., Kemmer, L., Khalid, N., Khalilov, R., Khammarnia, M., Khan, E. A., Khan, G., Khan, M., Khan, M. N., Khang, Y-H., Khatab, K., Khater, A. M., Khater, M. M., Khayamzadeh, M., Khosravi, A., Kim, D., Kim, Y-E., Kim, Y. J., Kimokoti, R. W., Kisa, A., Kisa, S., Kissoon, N., Kopec, J. A., Kosen, S., Koul, P. A., Laxminarayana, S. L. K., Koyanagi, A., Krishan, K., Krishnamoorthy, V., Defo, B. K., Bicer, B. K., Kulkarni, V., Kumar, G. A., Kumar, M., Kumar, N., Kurmi, O. P., Kusuma, D., La Vecchia, C., Lacey, B., Lalloo, R., Lami, F.H., Landires, I., Larsson, A. O., Lasrado, S., Lassi, Z. S., Lauriola, P., Lee, P. H., Lee, S. W. H., Lee, Y. H., Leigh, J., Leonardi, M., Lewycka, S., Li, B., Li, S., Liang, J., Lim, L-L., Limenih, M. A., Lin, R-T., Liu, X., Lodha, R., Lopez, A. D., Lozano, R., Lugo, A., Lunevicius, R., Mackay, M. T., Kunjathur, S. M., Magnani, F. G., Prasad, D. R. M., Maheri, M., Mahmoudi, M., Majeed, A., Maled, V., Maleki, A., Maleki, S., Malekzadeh, R., Malik, A. A., Malta, D. C., Mamun, A. A., Mansouri, B., Mansournia, M. A., Martinez, G., Martini, S., Martins-Melo, F. R., Masoumi, S. Z., Maulik, P. K., McAlinden, C., McGrath, J. J., Medina-Solis, C. E., Nasab, E. M., Mejia-Rodriguez, F., Memish, Z.A., Mendoza, W., Menezes, R. G., Mengesha, E. W., Mensah, G. A., Meretoja, A., Meretoja, T. J., Mersha, A. M., Mestrovic, T., Miazgowski, B., Miazgowski, T., Michalek, I. M., Miller, T.R., Mini, G. K., Miri, M., Mirica, A., Mirrakhimov, .E M., Mirzaei, H., Mirzaei, M., Moazen, B., Moghadaszadeh, M., Mohajer, B., Mohamad, O., Mohammad, Y., Mohammadi, S. M., Mohammadian-Hafshejani, A., Mohammed, S., Mokdad, A. H., Molokhia, M., Monasta, L., Mondello, S., Moni, M. A., Moore, C. E., Moradi, G., Moradi, M., Moradzadeh, R., Moraga, P., Morawska, L., Morrison, S. D., Mosser, J. F., Khaneghah, A. M., Mustafa, G., Naderi, M., Nagarajan, A. J., Nagaraju, S. P., Naghavi, M., Naghshtabrizi, B., Naimzada, M. D., Nangia, V., Swamy, S. N., Nascimento, B. R., Naveed, M., Nazari, J., Ndejjo, R., Negoi, I., Negoi, R. I., Nena, E., Nepal, S., Netsere, H. B., Nguefack-Tsague, G., Ngunjiri, J. W., Nguyen, C. T. Y., Nguyen, C. T., Nguyen, H. L. T., Nigatu, Y. T., Nigussie, S. N., Nixon, M. R., Nnaji, C. A., Nomura, S., Noor, N. M., Noubiap, J. J., Nunez-Samudio, V., Nwatah, V. E., Oancea, B., Odukoya, O. O., Ogbo, F. A., Olusanya, B. O., Olusanya, J. O., Bali, A. O., Onwujekwe, O. E., Ortiz, A., Otoiu, A., Otstavnov, N., Otstavnov, S. S., Owolabi, M. O., Mahesh, P. A., Padubidri, J. R., Pakhale, S., Pakshir, K., Pal, P. K., Palladino, R., Pana, A., Panda-Jonas, S., Pandey, A., Pandi-Perumal, S. R., Pangaribuan, H. U., Pardo-Montano, A. M., Park, E-K., Patel, S. K., Patton, G. C., Pawar, S., Toroudi, H. P., Peden, A. E., Pepito, V. C. F., Peprah, E. K., Pereira, J., Perez-Gomez, J., Perico, N., Pesudovs, K., Pilgrim, T., Pinheiro, M., Piradov, M. A., Pirsaheb, M., Platts-Mills, J. A., Pokhrel, K. N., Postma, M. J., Pourjafar, H., Prada, S. I., Prakash, S., Pupillo, E., Syed, Z. Q., Rabiee, N., Radfar, A., Rafiee, A., Rafiei, A., Raggi, A., Rahimzadeh, S., Rahman, M. H. U., Rahmani, A. M., Ramezanzadeh, K., Rana, J., Ranabhat, C. L., Rao, S. J., Rasella, D., Rastogi, P., Rathi, P., Rawaf, D. L., Rawaf, S., Rawasia, W. F., Rawassizadeh, R., Jr, R. C. R., Remuzzi, G., Renzaho, A. M. N., Reshmi, B., Resnikoff, S., Rezaei, N., Rezapour, A., Riahi, S. M., Ribeiro, D., Rickard, J., Roever, L., Ronfani, L., Rothenbacher, D., Rubagotti, E., Rumisha, S. F., Ryan, P. M., Saddik, B., Sadeghi, E., Moghaddam, S. S., Sagar, R., Sahebkar, A., Salahshoor, M. R., Salehi, S., Salem, M. R., Salimzadeh, H., Salomon, J. A., Samodra, Y. L., Samy, A. M., Sanabria, J., Santric-Milicevic, M. M., Saraswathy, S. Y. I., Sarker, A.R., Sarrafzadegan, N., Sarveazad, A., Sathian, B., Sathish, T., Sattin, D., Saxena, S., Saya, G. K., Saylan, M., Schiavolin, S., Schlaich, M. P., Schwebel, D. C., Schwendicke, F., Senthilkumaran, S., Sepanlou, S. G., Servan-Mori, E., Sha, F., Shafaat, O., Shahabi, S., Shahbaz, M., Shaheen, A. A., Shahid, I., Shaikh, M. A., Shakiba, S., Shalash, A. S., Shams-Beyranvand, M., Shannawaz, M., Sharafi, K., Sheikh, A., Sheikhbahaei, S., Shiferaw, W. S., Shigematsu, M., Shin, J. I. l., Shiri, R., Shiue, I., Shuval, K., Siddiqi, T. J., Sidemo, N. B., Sigfusdottir, I. D., Sigurvinsdottir, R., Silva, J. P., Silverberg, J. I. S., Simonetti, B., Singh, B.B., Singh, J. A., Singhal, D., Sinha, D. N., Skiadaresi, E., Skryabin, V. Y., Skryabina, A. A., Sleet, D. A., Sobaih, B. H., Sobhiyeh, M. R., Soltani, S., Soriano, J. B., Spurlock, E. E., Sreeramareddy, C. T., Steiropoulos, P., Stokes, M. A., Stortecky, S., Sufiyan, M. B., Abdulkader, R. S., Sulo, G., Swope, C. B., Sykes, B. L., Szeto, M. D., Szocska, M., Tabares-Seisdedos, R., Tadesse, E. G., Taherkhani, A., Tamiru, A.T., Tareque, M. I., Tehrani-Banihashemi, A., Temsah, M-H., Tesfay, F. H., Tessema, G. A., Tessema, Z. T., Thankappan, K. R., Thapar, R., Tolani, M. A., Tovani-Palone, M. R., Traini, E., Tran, B. X., Tripathy, J. P., Tsapparellas, G., Tsatsakis, A., Car, L. T., Uddin, R., Ullah, A., Umeokonkwo, C. D., Unim, B., Unnikrishnan, B., Upadhyay, E., Usman, M. S., Vacante, M., Vaezi, M., Tahbaz, S. V., Valdez, P. R., Vasankari, T. J., Venketasubramanian, N., Verma, M., Violante, F. S., Vlassov, V., Vo, B., Vu, G. T., Wado, Y. D., Waheed, Y., Wamai, R. G., Wang, Y., Wang, Y-P., Ward, P., Werdecker, A., Westerman, R., Wickramasinghe, N. D., Wilner, L. B., Wiysonge, C. S., Wu, A-M., Wu, C., Xie, Y., Jabbari, S. H. Y., Yamagishi, K., Yandrapalli, S., Yaya, S., Yazdi-Feyzabadi, V., Yip, P., Yonemoto, N., Yoon, S-J., Younis, M. Z., Yousefi, Z., Yousefinezhadi, T., Yu, C., Yusuf, S. S., Zaidi, S. S., Bin Zaman, S., Zamani, M., Zamanian, M., Zastrozhin, M. S., Zastrozhina, A., Zhang, Y., Zhang, Z-J., Zhao, X-J. G., Ziapour, A., Hay, S. I., Murray, C. J. L., Wang, H., Kassebaum, N. J., GBD 2019 Under-5 Mortality Collaborators, Paulson K.R., Kamath A.M., Alam T., Bienhoff K., Abady G.G., Abbas J., Abbasi-Kangevari M., Abbastabar H., Abd-Allah F., Abd-Elsalam S.M., Abdoli A., Abedi A., Abolhassani H., Abreu L.G., Abu-Gharbieh E., Abu-Rmeileh N.M., Abushouk A.I., Adamu A.L., Adebayo O.M., Adegbosin A.E., Adekanmbi V., Adetokunboh O.O., Adeyinka D.A., Adsuar J.C., Afshari K., Aghaali M., Agudelo-Botero M., Ahinkorah B.O., Ahmad T., Ahmadi K., Ahmed M.B., Aji B., Akalu Y., Akinyemi O.O., Aklilu A., Al-Aly Z., Alam K., Alanezi F.M., Alanzi T.M., Alcalde-Rabanal J.E., Al-Eyadhy A., Ali T., Alicandro G., Alif S.M., Alipour V., Alizade H., Aljunid S.M., Almasi-Hashiani A., Almasri N.A., Al-Mekhlafi H.M., Alonso J., Al-Raddadi R.M., Altirkawi K.A., Alumran A.K., Alvis-Guzman N., Alvis-Zakzuk N.J., Ameyaw E.K., Amini S., Amini-Rarani M., Amit A.M.L., Amugsi D.A., Ancuceanu R., Anderlini D., Andrei C.L., Ansari F., Ansari-Moghaddam A., Antonio C.A.T., Antriyandarti E., Anvari D., Anwer R., Aqeel M., Arabloo J., Arab-Zozani M., Aripov T., Arnlov J., Artanti K.D., Arzani A., Asaad M., Asadi-Aliabadi M., Asadi-Pooya A.A., Asghari Jafarabadi M., Athari S.S., Athari S.M., Atnafu D.D., Atreya A., Atteraya M.S., Ausloos M., Awan A.T., Ayala Quintanilla B.P., Ayano G., Ayanore M.A., Aynalem Y.A., Azari S., Azarian G., Azene Z.N., B D.B., Babaee E., Badiye A.D., Baig A.A., Banach M., Banik P.C., Barker-Collo S.L., Barqawi H.J., Bassat Q., Basu S., Baune B.T., Bayati M., Bedi N., Beghi E., Beghi M., Bell M.L., Bendak S., Bennett D.A., Bensenor I.M., Berhe K., Berman A.E., Bezabih Y.M., Bhagavathula A.S., Bhandari D., Bhardwaj N., Bhardwaj P., Bhattacharyya K., Bhattarai S., Bhutta Z.A., Bikbov B., Biondi A., Birihane B.M., Biswas R.K., Bohlouli S., Bragazzi N.L., Breusov A.V., Brunoni A.R., Burkart K., Burugina Nagaraja S., Busse R., Butt Z.A., Caetano dos Santos F.L., Cahuana-Hurtado L., Camargos P., Camera L.A., Cardenas R., Carreras G., Carrero J.J., Carvalho F., Castaldelli-Maia J.M., Castaneda-Orjuela C.A., Castelpietra G., Cerin E., Chang J.-C., Chanie W.F., Charan J., Chatterjee S., Chattu S.K., Chattu V.K., Chaturvedi S., Chen S., Cho D.Y., Choi J.-Y.J., Chu D.-T., Ciobanu L.G., Cirillo M., Conde J., Costa V.M., Couto R.A.S., Dachew B.A., Dahlawi S.M.A., Dai H., Dai X., Dandona L., Dandona R., Daneshpajouhnejad P., Darmstadt G.L., Das J.K., Davila-Cervantes C.A., Davis A.C., Davletov K., De la Hoz F.P., De Leo D., Deeba F., Denova-Gutierrez E., Dervenis N., Desalew A., Deuba K., Dey S., Dharmaratne S.D., Dhingra S., Dhungana G.P., Dias da Silva D., Diaz D., Dorostkar F., Doshmangir L., Dubljanin E., Duraes A.R., Eagan A.W., Edinur H.A., Efendi F., Eftekharzadeh S., El Sayed I., El Tantawi M., Elbarazi I., Elgendy I.Y., El-Jaafary S.I., Emami A., Enany S., Eyawo O., Ezzikouri S., Faris P.S., Farzadfar F., Fattahi N., Fauk N.K., Fazlzadeh M., Feigin V.L., Ferede T.Y., Fereshtehnejad S.-M., Fernandes E., Ferrara P., Filip I., Fischer F., Fisher J.L., Foigt N.A., Folayan M.O., Foroutan M., Franklin R.C., Freitas M., Friedman S.D., Fukumoto T., Gad M.M., Gaidhane A.M., Gaidhane S., Gaihre S., Gallus S., Garcia-Basteiro A.L., Garcia-Gordillo M.A., Gardner W.M., Gaspar Fonseca M., Gebremedhin K.B., Getacher L., Ghashghaee A., Gholamian A., Gilani S.A., Gill T.K., Giussani G., Gnedovskaya E.V., Godinho M.A., Goel A., Golechha M., Gona P.N., Gopalani S.V., Goudarzi H., Grivna M., Gugnani H.C., Guido D., Guimaraes R.A., Gupta R.D., Gupta R., Hafezi-Nejad N., Haider M.R., Haj-Mirzaian A., Hamidi S., Hanif A., Hankey G.J., Hargono A., Hasaballah A.I., Hasan M.M., Hasan S.S., Hassan A., Hassanipour S., Hassankhani H., Havmoeller R.J., Hayat K., Heidari-Soureshjani R., Henry N.J., Herteliu C., Hole M.K., Holla R., Hossain N., Hosseini M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Househ M., Huang J., Humayun A., Hwang B.-F., Iavicoli I., Ibitoye S.E., Ikuta K.S., Ilesanmi O.S., Ilic I.M., Ilic M.D., Inamdar S., Inbaraj L.R., Iqbal K., Iqbal U., Islam M.M., Islam S.M.S., Iso H., Iwagami M., Iwu C.C.D., Jaafari J., Jacobsen K.H., Jagnoor J., Jain V., Janodia M.D., Javaheri T., Javanmardi F., Jayaram S., Jayatilleke A.U., Jenabi E., Jha R.P., Ji J.S., John O., Jonas J.B., Joo T., Joseph N., Joukar F., Jozwiak J.J., Jurisson M., Kabir A., Kabir Z., Kalankesh L.R., Kamyari N., Kanchan T., Kapoor N., Karami Matin B., Karch A., Karimi S.E., Kassahun G., Kayode G.A., Kazemi Karyani A., Kemmer L., Khalid N., Khalilov R., Khammarnia M., Khan E.A., Khan G., Khan M., Khan M.N., Khang Y.-H., Khatab K., Khater A.M., Khater M.M., Khayamzadeh M., Khosravi A., Kim D., Kim Y.-E., Kim Y.J., Kimokoti R.W., Kisa A., Kisa S., Kissoon N., Kopec J.A., Kosen S., Koul P.A., Koulmane Laxminarayana S.L., Koyanagi A., Krishan K., Krishnamoorthy V., Kuate Defo B., Kucuk Bicer B., Kulkarni V., Kumar G.A., Kumar M., Kumar N., Kurmi O.P., Kusuma D., La Vecchia C., Lacey B., Lalloo R., Lami F.H., Landires I., Larsson A.O., Lasrado S., Lassi Z.S., Lauriola P., Lee P.H., Lee S.W.H., Lee Y.H., Leigh J., Leonardi M., Lewycka S., Li B., Li S., Liang J., Lim L.-L., Limenih M.A., Lin R.-T., Liu X., Lodha R., Lopez A.D., Lozano R., Lugo A., Lunevicius R., Mackay M.T., Madhava Kunjathur S., Magnani F.G., Mahadeshwara Prasad D.R., Maheri M., Mahmoudi M., Majeed A., Maled V., Maleki A., Maleki S., Malekzadeh R., Malik A.A., Malta D.C., Mamun A.A., Mansouri B., Mansournia M.A., Martinez G., Martini S., Martins-Melo F.R., Masoumi S.Z., Maulik P.K., McAlinden C., McGrath J.J., Medina-Solis C.E., Mehrabi Nasab E., Mejia-Rodriguez F., Memish Z.A., Mendoza W., Menezes R.G., Mengesha E.W., Mensah G.A., Meretoja A., Meretoja T.J., Mersha A.M., Mestrovic T., Miazgowski B., Miazgowski T., Michalek I.M., Miller T.R., Mini G.K., Miri M., Mirica A., Mirrakhimov E.M., Mirzaei H., Mirzaei M., Moazen B., Moghadaszadeh M., Mohajer B., Mohamad O., Mohammad Y., Mohammadi S.M., Mohammadian-Hafshejani A., Mohammed S., Mokdad A.H., Molokhia M., Monasta L., Mondello S., Moni M.A., Moore C.E., Moradi G., Moradi M., Moradzadeh R., Moraga P., Morawska L., Morrison S.D., Mosser J.F., Mousavi Khaneghah A., Mustafa G., Naderi M., Nagarajan A.J., Nagaraju S.P., Naghavi M., Naghshtabrizi B., Naimzada M.D., Nangia V., Narasimha Swamy S., Nascimento B.R., Naveed M., Nazari J., Ndejjo R., Negoi I., Negoi R.I., Nena E., Nepal S., Netsere H.B., Nguefack-Tsague G., Ngunjiri J.W., Nguyen C.T.Y., Nguyen C.T., Nguyen H.L.T., Nigatu Y.T., Nigussie S.N., Nixon M.R., Nnaji C.A., Nomura S., Noor N.M., Noubiap J.J., Nunez-Samudio V., Nwatah V.E., Oancea B., Odukoya O.O., Ogbo F.A., Olusanya B.O., Olusanya J.O., Omar Bali A., Onwujekwe O.E., Ortiz A., Otoiu A., Otstavnov N., Otstavnov S.S., Owolabi M.O., P A M., Padubidri J.R., Pakhale S., Pakshir K., Pal P.K., Palladino R., Pana A., Panda-Jonas S., Pandey A., Pandi-Perumal S.R., Pangaribuan H.U., Pardo-Montano A.M., Park E.-K., Patel S.K., Patton G.C., Pawar S., Pazoki Toroudi H., Peden A.E., Pepito V.C.F., Peprah E.K., Pereira J., Perez-Gomez J., Perico N., Pesudovs K., Pilgrim T., Pinheiro M., Piradov M.A., Pirsaheb M., Platts-Mills J.A., Pokhrel K.N., Postma M.J., Pourjafar H., Prada S.I., Prakash S., Pupillo E., Quazi Syed Z., Rabiee N., Radfar A., Rafiee A., Rafiei A., Raggi A., Rahimzadeh S., Rahman M.H.U., Rahmani A.M., Ramezanzadeh K., Rana J., Ranabhat C.L., Rao S.J., Rasella D., Rastogi P., Rathi P., Rawaf D.L., Rawaf S., Rawasia W.F., Rawassizadeh R., Reiner R.C., Remuzzi G., Renzaho A.M.N., Reshmi B., Resnikoff S., Rezaei N., Rezapour A., Riahi S.M., Ribeiro D., Rickard J., Roever L., Ronfani L., Rothenbacher D., Rubagotti E., Rumisha S.F., Ryan P.M., Saddik B., Sadeghi E., Saeedi Moghaddam S., Sagar R., Sahebkar A., Salahshoor M.R., Salehi S., Salem M.R., Salimzadeh H., Salomon J.A., Samodra Y.L., Samy A.M., Sanabria J., Santric-Milicevic M.M., Saraswathy S.Y.I., Sarker A.R., Sarrafzadegan N., Sarveazad A., Sathian B., Sathish T., Sattin D., Saxena S., Saya G.K., Saylan M., Schiavolin S., Schlaich M.P., Schwebel D.C., Schwendicke F., Senthilkumaran S., Sepanlou S.G., Servan-Mori E., Sha F., Shafaat O., Shahabi S., Shahbaz M., Shaheen A.A., Shahid I., Shaikh M.A., Shakiba S., Shalash A.S., Shams-Beyranvand M., Shannawaz M., Sharafi K., Sheikh A., Sheikhbahaei S., Shiferaw W.S., Shigematsu M., Shin J.I., Shiri R., Shiue I., Shuval K., Siddiqi T.J., Sidemo N.B., Sigfusdottir I.D., Sigurvinsdottir R., Silva J.P., Silverberg J.I.S., Simonetti B., Singh B.B., Singh J.A., Singhal D., Sinha D.N., Skiadaresi E., Skryabin V.Y., Skryabina A.A., Sleet D.A., Sobaih B.H., Sobhiyeh M.R., Soltani S., Soriano J.B., Spurlock E.E., Sreeramareddy C.T., Steiropoulos P., Stokes M.A., Stortecky S., Sufiyan M.B., Suliankatchi Abdulkader R., Sulo G., Swope C.B., Sykes B.L., Szeto M.D., Szocska M., Tabares-Seisdedos R., Tadesse E.G., Taherkhani A., Tamiru A.T., Tareque M.I., Tehrani-Banihashemi A., Temsah M.-H., Tesfay F.H., Tessema G.A., Tessema Z.T., Thankappan K.R., Thapar R., Tolani M.A., Tovani-Palone M.R., Traini E., Tran B.X., Tripathy J.P., Tsapparellas G., Tsatsakis A., Tudor Car L., Uddin R., Ullah A., Umeokonkwo C.D., Unim B., Unnikrishnan B., Upadhyay E., Usman M.S., Vacante M., Vaezi M., Valadan Tahbaz S., Valdez P.R., Vasankari T.J., Venketasubramanian N., Verma M., Violante F.S., Vlassov V., Vo B., Vu G.T., Wado Y.D., Waheed Y., Wamai R.G., Wang Y., Wang Y.-P., Ward P., Werdecker A., Westerman R., Wickramasinghe N.D., Wilner L.B., Wiysonge C.S., Wu A.-M., Wu C., Xie Y., Yahyazadeh Jabbari S.H., Yamagishi K., Yandrapalli S., Yaya S., Yazdi-Feyzabadi V., Yip P., Yonemoto N., Yoon S.-J., Younis M.Z., Yousefi Z., Yousefinezhadi T., Yu C., Yusuf S.S., Zaidi S.S., Zaman S.B., Zamani M., Zamanian M., Zastrozhin M.S., Zastrozhina A., Zhang Y., Zhang Z.-J., Zhao X.-J.G., Ziapour A., Hay S.I., Murray C.J.L., Wang H., Kassebaum N.J., Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), Paulson, K. R., Kamath, A. M., Alam, T., Bienhoff, K., Abady, G. G., Abbas, J., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., Abd-Elsalam, S. M., Abdoli, A., Abedi, A., Abolhassani, H., Abreu, L. G., Abu-Gharbieh, E., Abu-Rmeileh, N. M., Abushouk, A. I., Adamu, A. L., Adebayo, O. M., Adegbosin, A. E., Adekanmbi, V., Adetokunboh, O. O., Adeyinka, D. A., Adsuar, J. C., Afshari, K., Aghaali, M., Agudelo-Botero, M., Ahinkorah, B. O., Ahmad, T., Ahmadi, K., Ahmed, M. B., Aji, B., Akalu, Y., Akinyemi, O. O., Aklilu, A., Al-Aly, Z., Alam, K., Alanezi, F. M., Alanzi, T. M., Alcalde-Rabanal, J. E., Al-Eyadhy, A., Ali, T., Alicandro, G., Alif, S. M., Alipour, V., Alizade, H., Aljunid, S. M., Almasi-Hashiani, A., Almasri, N. A., Al-Mekhlafi, H. M., Alonso, J., Al-Raddadi, R. M., Altirkawi, K. A., Alumran, A. K., Alvis-Guzman, N., Alvis-Zakzuk, N. J., Ameyaw, E. K., Amini, S., Amini-Rarani, M., Amit, A. M. L., Amugsi, D. A., Ancuceanu, R., Anderlini, D., Andrei, C. L., Ansari, F., Ansari-Moghaddam, A., Antonio, C. A. T., Antriyandarti, E., Anvari, D., Anwer, R., Aqeel, M., Arabloo, J., Arab-Zozani, M., Aripov, T., Arnlov, J., Artanti, K. D., Arzani, A., Asaad, M., Asadi-Aliabadi, M., Asadi-Pooya, A. A., Asghari Jafarabadi, M., Athari, S. S., Athari, S. M., Atnafu, D. D., Atreya, A., Atteraya, M. S., Ausloos, M., Awan, A. T., Ayala Quintanilla, B. P., Ayano, G., Ayanore, M. A., Aynalem, Y. A., Azari, S., Azarian, G., Azene, Z. N., B, D. B., Babaee, E., Badiye, A. D., Baig, A. A., Banach, M., Banik, P. C., Barker-Collo, S. L., Barqawi, H. J., Bassat, Q., Basu, S., Baune, B. T., Bayati, M., Bedi, N., Beghi, E., Beghi, M., Bell, M. L., Bendak, S., Bennett, D. A., Bensenor, I. M., Berhe, K., Berman, A. E., Bezabih, Y. M., Bhagavathula, A. S., Bhandari, D., Bhardwaj, N., Bhardwaj, P., Bhattacharyya, K., Bhattarai, S., Bhutta, Z. A., Bikbov, B., Biondi, A., Birihane, B. M., Biswas, R. K., Bohlouli, S., Bragazzi, N. L., Breusov, A. V., Brunoni, A. R., Burkart, K., Burugina Nagaraja, S., Busse, R., Butt, Z. A., Caetano dos Santos, F. L., Cahuana-Hurtado, L., Camargos, P., Camera, L. A., Cardenas, R., Carreras, G., Carrero, J. J., Carvalho, F., Castaldelli-Maia, J. M., Castaneda-Orjuela, C. A., Castelpietra, G., Cerin, E., Chang, J. -C., Chanie, W. F., Charan, J., Chatterjee, S., Chattu, S. K., Chattu, V. K., Chaturvedi, S., Chen, S., Cho, D. Y., Choi, J. -Y. J., Chu, D. -T., Ciobanu, L. G., Cirillo, M., Conde, J., Costa, V. M., Couto, R. A. S., Dachew, B. A., Dahlawi, S. M. A., Dai, H., Dai, X., Dandona, L., Dandona, R., Daneshpajouhnejad, P., Darmstadt, G. L., Das, J. K., Davila-Cervantes, C. A., Davis, A. C., Davletov, K., De la Hoz, F. P., De Leo, D., Deeba, F., Denova-Gutierrez, E., Dervenis, N., Desalew, A., Deuba, K., Dey, S., Dharmaratne, S. D., Dhingra, S., Dhungana, G. P., Dias da Silva, D., Diaz, D., Dorostkar, F., Doshmangir, L., Dubljanin, E., Duraes, A. R., Eagan, A. W., Edinur, H. A., Efendi, F., Eftekharzadeh, S., El Sayed, I., El Tantawi, M., Elbarazi, I., Elgendy, I. Y., El-Jaafary, S. I., Emami, A., Enany, S., Eyawo, O., Ezzikouri, S., Faris, P. S., Farzadfar, F., Fattahi, N., Fauk, N. K., Fazlzadeh, M., Feigin, V. L., Ferede, T. Y., Fereshtehnejad, S. -M., Fernandes, E., Ferrara, P., Filip, I., Fischer, F., Fisher, J. L., Foigt, N. A., Folayan, M. O., Foroutan, M., Franklin, R. C., Freitas, M., Friedman, S. D., Fukumoto, T., Gad, M. M., Gaidhane, A. M., Gaidhane, S., Gaihre, S., Gallus, S., Garcia-Basteiro, A. L., Garcia-Gordillo, M. A., Gardner, W. M., Gaspar Fonseca, M., Gebremedhin, K. B., Getacher, L., Ghashghaee, A., Gholamian, A., Gilani, S. A., Gill, T. K., Giussani, G., Gnedovskaya, E. V., Godinho, M. A., Goel, A., Golechha, M., Gona, P. N., Gopalani, S. V., Goudarzi, H., Grivna, M., Gugnani, H. C., Guido, D., Guimaraes, R. A., Gupta, R. D., Gupta, R., Hafezi-Nejad, N., Haider, M. R., Haj-Mirzaian, A., Hamidi, S., Hanif, A., Hankey, G. J., Hargono, A., Hasaballah, A. I., Hasan, M. M., Hasan, S. S., Hassan, A., Hassanipour, S., Hassankhani, H., Havmoeller, R. J., Hayat, K., Heidari-Soureshjani, R., Henry, N. J., Herteliu, C., Hole, M. K., Holla, R., Hossain, N., Hosseini, M., Hosseinzadeh, M., Hostiuc, M., Hostiuc, S., Househ, M., Huang, J., Humayun, A., Hwang, B. -F., Iavicoli, I., Ibitoye, S. E., Ikuta, K. S., Ilesanmi, O. S., Ilic, I. M., Ilic, M. D., Inamdar, S., Inbaraj, L. R., Iqbal, K., Iqbal, U., Islam, M. M., Islam, S. M. S., Iso, H., Iwagami, M., Iwu, C. C. D., Jaafari, J., Jacobsen, K. H., Jagnoor, J., Jain, V., Janodia, M. D., Javaheri, T., Javanmardi, F., Jayaram, S., Jayatilleke, A. U., Jenabi, E., Jha, R. P., Ji, J. S., John, O., Jonas, J. B., Joo, T., Joseph, N., Joukar, F., Jozwiak, J. J., Jurisson, M., Kabir, A., Kabir, Z., Kalankesh, L. R., Kamyari, N., Kanchan, T., Kapoor, N., Karami Matin, B., Karch, A., Karimi, S. E., Kassahun, G., Kayode, G. A., Kazemi Karyani, A., Kemmer, L., Khalid, N., Khalilov, R., Khammarnia, M., Khan, E. A., Khan, G., Khan, M., Khan, M. N., Khang, Y. -H., Khatab, K., Khater, A. M., Khater, M. M., Khayamzadeh, M., Khosravi, A., Kim, D., Kim, Y. -E., Kim, Y. J., Kimokoti, R. W., Kisa, A., Kisa, S., Kissoon, N., Kopec, J. A., Kosen, S., Koul, P. A., Koulmane Laxminarayana, S. L., Koyanagi, A., Krishan, K., Krishnamoorthy, V., Kuate Defo, B., Kucuk Bicer, B., Kulkarni, V., Kumar, G. A., Kumar, M., Kumar, N., Kurmi, O. P., Kusuma, D., La Vecchia, C., Lacey, B., Lalloo, R., Lami, F. H., Landires, I., Larsson, A. O., Lasrado, S., Lassi, Z. S., Lauriola, P., Lee, P. H., Lee, S. W. H., Lee, Y. H., Leigh, J., Leonardi, M., Lewycka, S., Li, B., Li, S., Liang, J., Lim, L. -L., Limenih, M. A., Lin, R. -T., Liu, X., Lodha, R., Lopez, A. D., Lozano, R., Lugo, A., Lunevicius, R., Mackay, M. T., Madhava Kunjathur, S., Magnani, F. G., Mahadeshwara Prasad, D. R., Maheri, M., Mahmoudi, M., Majeed, A., Maled, V., Maleki, A., Maleki, S., Malekzadeh, R., Malik, A. A., Malta, D. C., Mamun, A. A., Mansouri, B., Mansournia, M. A., Martinez, G., Martini, S., Martins-Melo, F. R., Masoumi, S. Z., Maulik, P. K., Mcalinden, C., Mcgrath, J. J., Medina-Solis, C. E., Mehrabi Nasab, E., Mejia-Rodriguez, F., Memish, Z. A., Mendoza, W., Menezes, R. G., Mengesha, E. W., Mensah, G. A., Meretoja, A., Meretoja, T. J., Mersha, A. M., Mestrovic, T., Miazgowski, B., Miazgowski, T., Michalek, I. M., Miller, T. R., Mini, G. K., Miri, M., Mirica, A., Mirrakhimov, E. M., Mirzaei, H., Mirzaei, M., Moazen, B., Moghadaszadeh, M., Mohajer, B., Mohamad, O., Mohammad, Y., Mohammadi, S. M., Mohammadian-Hafshejani, A., Mohammed, S., Mokdad, A. H., Molokhia, M., Monasta, L., Mondello, S., Moni, M. A., Moore, C. E., Moradi, G., Moradi, M., Moradzadeh, R., Moraga, P., Morawska, L., Morrison, S. D., Mosser, J. F., Mousavi Khaneghah, A., Mustafa, G., Naderi, M., Nagarajan, A. J., Nagaraju, S. P., Naghavi, M., Naghshtabrizi, B., Naimzada, M. D., Nangia, V., Narasimha Swamy, S., Nascimento, B. R., Naveed, M., Nazari, J., Ndejjo, R., Negoi, I., Negoi, R. I., Nena, E., Nepal, S., Netsere, H. B., Nguefack-Tsague, G., Ngunjiri, J. W., Nguyen, C. T. Y., Nguyen, C. T., Nguyen, H. L. T., Nigatu, Y. T., Nigussie, S. N., Nixon, M. R., Nnaji, C. A., Nomura, S., Noor, N. M., Noubiap, J. J., Nunez-Samudio, V., Nwatah, V. E., Oancea, B., Odukoya, O. O., Ogbo, F. A., Olusanya, B. O., Olusanya, J. O., Omar Bali, A., Onwujekwe, O. E., Ortiz, A., Otoiu, A., Otstavnov, N., Otstavnov, S. S., Owolabi, M. O., P A, M., Padubidri, J. R., Pakhale, S., Pakshir, K., Pal, P. K., Palladino, R., Pana, A., Panda-Jonas, S., Pandey, A., Pandi-Perumal, S. R., Pangaribuan, H. U., Pardo-Montano, A. M., Park, E. -K., Patel, S. K., Patton, G. C., Pawar, S., Pazoki Toroudi, H., Peden, A. E., Pepito, V. C. F., Peprah, E. K., Pereira, J., Perez-Gomez, J., Perico, N., Pesudovs, K., Pilgrim, T., Pinheiro, M., Piradov, M. A., Pirsaheb, M., Platts-Mills, J. A., Pokhrel, K. N., Postma, M. J., Pourjafar, H., Prada, S. I., Prakash, S., Pupillo, E., Quazi Syed, Z., Rabiee, N., Radfar, A., Rafiee, A., Rafiei, A., Raggi, A., Rahimzadeh, S., Rahman, M. H. U., Rahmani, A. M., Ramezanzadeh, K., Rana, J., Ranabhat, C. L., Rao, S. J., Rasella, D., Rastogi, P., Rathi, P., Rawaf, D. L., Rawaf, S., Rawasia, W. F., Rawassizadeh, R., Reiner, R. C., Remuzzi, G., Renzaho, A. M. N., Reshmi, B., Resnikoff, S., Rezaei, N., Rezapour, A., Riahi, S. M., Ribeiro, D., Rickard, J., Roever, L., Ronfani, L., Rothenbacher, D., Rubagotti, E., Rumisha, S. F., Ryan, P. M., Saddik, B., Sadeghi, E., Saeedi Moghaddam, S., Sagar, R., Sahebkar, A., Salahshoor, M. R., Salehi, S., Salem, M. R., Salimzadeh, H., Salomon, J. A., Samodra, Y. L., Samy, A. M., Sanabria, J., Santric-Milicevic, M. M., Saraswathy, S. Y. I., Sarker, A. R., Sarrafzadegan, N., Sarveazad, A., Sathian, B., Sathish, T., Sattin, D., Saxena, S., Saya, G. K., Saylan, M., Schiavolin, S., Schlaich, M. P., Schwebel, D. C., Schwendicke, F., Senthilkumaran, S., Sepanlou, S. G., Servan-Mori, E., Sha, F., Shafaat, O., Shahabi, S., Shahbaz, M., Shaheen, A. A., Shahid, I., Shaikh, M. A., Shakiba, S., Shalash, A. S., Shams-Beyranvand, M., Shannawaz, M., Sharafi, K., Sheikh, A., Sheikhbahaei, S., Shiferaw, W. S., Shigematsu, M., Shin, J. I., Shiri, R., Shiue, I., Shuval, K., Siddiqi, T. J., Sidemo, N. B., Sigfusdottir, I. D., Sigurvinsdottir, R., Silva, J. P., Silverberg, J. I. S., Simonetti, B., Singh, B. B., Singh, J. A., Singhal, D., Sinha, D. N., Skiadaresi, E., Skryabin, V. Y., Skryabina, A. A., Sleet, D. A., Sobaih, B. H., Sobhiyeh, M. R., Soltani, S., Soriano, J. B., Spurlock, E. E., Sreeramareddy, C. T., Steiropoulos, P., Stokes, M. A., Stortecky, S., Sufiyan, M. B., Suliankatchi Abdulkader, R., Sulo, G., Swope, C. B., Sykes, B. L., Szeto, M. D., Szocska, M., Tabares-Seisdedos, R., Tadesse, E. G., Taherkhani, A., Tamiru, A. T., Tareque, M. I., Tehrani-Banihashemi, A., Temsah, M. -H., Tesfay, F. H., Tessema, G. A., Tessema, Z. T., Thankappan, K. R., Thapar, R., Tolani, M. A., Tovani-Palone, M. R., Traini, E., Tran, B. X., Tripathy, J. P., Tsapparellas, G., Tsatsakis, A., Tudor Car, L., Uddin, R., Ullah, A., Umeokonkwo, C. D., Unim, B., Unnikrishnan, B., Upadhyay, E., Usman, M. S., Vacante, M., Vaezi, M., Valadan Tahbaz, S., Valdez, P. R., Vasankari, T. J., Venketasubramanian, N., Verma, M., Violante, F. S., Vlassov, V., Vo, B., Vu, G. T., Wado, Y. D., Waheed, Y., Wamai, R. G., Wang, Y., Wang, Y. -P., Ward, P., Werdecker, A., Westerman, R., Wickramasinghe, N. D., Wilner, L. B., Wiysonge, C. S., Wu, A. -M., Wu, C., Xie, Y., Yahyazadeh Jabbari, S. H., Yamagishi, K., Yandrapalli, S., Yaya, S., Yazdi-Feyzabadi, V., Yip, P., Yonemoto, N., Yoon, S. -J., Younis, M. Z., Yousefi, Z., Yousefinezhadi, T., Yu, C., Yusuf, S. S., Zaidi, S. S., Zaman, S. B., Zamani, M., Zamanian, M., Zastrozhin, M. S., Zastrozhina, A., Zhang, Y., Zhang, Z. -J., Zhao, X. -J. G., Ziapour, A., Hay, S. I., Murray, C. J. L., Wang, H., Kassebaum, N. J., Clinicum, Neurologian yksikkö, HUS Neurocenter, HUS Comprehensive Cancer Center, University of Helsinki, Department of Oncology, Paulson, K, Kamath, A, Alam, T, Bienhoff, K, Abady, G, Abbas, J, Abbasi-Kangevari, M, Abbastabar, H, Abd-Allah, F, Abd-Elsalam, S, Abdoli, A, Abedi, A, Abolhassani, H, Abreu, L, Abu-Gharbieh, E, Abu-Rmeileh, N, Abushouk, A, Adamu, A, Adebayo, O, Adegbosin, A, Adekanmbi, V, Adetokunboh, O, Adeyinka, D, Adsuar, J, Afshari, K, Aghaali, M, Agudelo-Botero, M, Ahinkorah, B, Ahmad, T, Ahmadi, K, Ahmed, M, Aji, B, Akalu, Y, Akinyemi, O, Aklilu, A, Al-Aly, Z, Alam, K, Alanezi, F, Alanzi, T, Alcalde-Rabanal, J, Al-Eyadhy, A, Ali, T, Alicandro, G, Alif, S, Alipour, V, Alizade, H, Aljunid, S, Almasi-Hashiani, A, Almasri, N, Al-Mekhlafi, H, Alonso, J, Al-Raddadi, R, Altirkawi, K, Alumran, A, Alvis-Guzman, N, Alvis-Zakzuk, N, Ameyaw, E, Amini, S, Amini-Rarani, M, Amit, A, Amugsi, D, Ancuceanu, R, Anderlini, D, Andrei, C, Ansari, F, Ansari-Moghaddam, A, Antonio, C, Antriyandarti, E, Anvari, D, Anwer, R, Aqeel, M, Arabloo, J, Arab-Zozani, M, Aripov, T, Arnlov, J, Artanti, K, Arzani, A, Asaad, M, Asadi-Aliabadi, M, Asadi-Pooya, A, Asghari Jafarabadi, M, Athari, S, Atnafu, D, Atreya, A, Atteraya, M, Ausloos, M, Awan, A, Ayala Quintanilla, B, Ayano, G, Ayanore, M, Aynalem, Y, Azari, S, Azarian, G, Azene, Z, B, D, Babaee, E, Badiye, A, Baig, A, Banach, M, Banik, P, Barker-Collo, S, Barqawi, H, Bassat, Q, Basu, S, Baune, B, Bayati, M, Bedi, N, Beghi, E, Beghi, M, Bell, M, Bendak, S, Bennett, D, Bensenor, I, Berhe, K, Berman, A, Bezabih, Y, Bhagavathula, A, Bhandari, D, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bhattarai, S, Bhutta, Z, Bikbov, B, Biondi, A, Birihane, B, Biswas, R, Bohlouli, S, Bragazzi, N, Breusov, A, Brunoni, A, Burkart, K, Burugina Nagaraja, S, Busse, R, Butt, Z, Caetano dos Santos, F, Cahuana-Hurtado, L, Camargos, P, Camera, L, Cardenas, R, Carreras, G, Carrero, J, Carvalho, F, Castaldelli-Maia, J, Castaneda-Orjuela, C, Castelpietra, G, Cerin, E, Chang, J, Chanie, W, Charan, J, Chatterjee, S, Chattu, S, Chattu, V, Chaturvedi, S, Chen, S, Cho, D, Choi, J, Chu, D, Ciobanu, L, Cirillo, M, Conde, J, Costa, V, Couto, R, Dachew, B, Dahlawi, S, Dai, H, Dai, X, Dandona, L, Dandona, R, Daneshpajouhnejad, P, Darmstadt, G, Das, J, Davila-Cervantes, C, Davis, A, Davletov, K, De la Hoz, F, De Leo, D, Deeba, F, Denova-Gutierrez, E, Dervenis, N, Desalew, A, Deuba, K, Dey, S, Dharmaratne, S, Dhingra, S, Dhungana, G, Dias da Silva, D, Diaz, D, Dorostkar, F, Doshmangir, L, Dubljanin, E, Duraes, A, Eagan, A, Edinur, H, Efendi, F, Eftekharzadeh, S, El Sayed, I, El Tantawi, M, Elbarazi, I, Elgendy, I, El-Jaafary, S, Emami, A, Enany, S, Eyawo, O, Ezzikouri, S, Faris, P, Farzadfar, F, Fattahi, N, Fauk, N, Fazlzadeh, M, Feigin, V, Ferede, T, Fereshtehnejad, S, Fernandes, E, Ferrara, P, Filip, I, Fischer, F, Fisher, J, Foigt, N, Folayan, M, Foroutan, M, Franklin, R, Freitas, M, Friedman, S, Fukumoto, T, Gad, M, Gaidhane, A, Gaidhane, S, Gaihre, S, Gallus, S, Garcia-Basteiro, A, Garcia-Gordillo, M, Gardner, W, Gaspar Fonseca, M, Gebremedhin, K, Getacher, L, Ghashghaee, A, Gholamian, A, Gilani, S, Gill, T, Giussani, G, Gnedovskaya, E, Godinho, M, Goel, A, Golechha, M, Gona, P, Gopalani, S, Goudarzi, H, Grivna, M, Gugnani, H, Guido, D, Guimaraes, R, Gupta, R, Hafezi-Nejad, N, Haider, M, Haj-Mirzaian, A, Hamidi, S, Hanif, A, Hankey, G, Hargono, A, Hasaballah, A, Hasan, M, Hasan, S, Hassan, A, Hassanipour, S, Hassankhani, H, Havmoeller, R, Hayat, K, Heidari-Soureshjani, R, Henry, N, Herteliu, C, Hole, M, Holla, R, Hossain, N, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Huang, J, Humayun, A, Hwang, B, Iavicoli, I, Ibitoye, S, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Inamdar, S, Inbaraj, L, Iqbal, K, Iqbal, U, Islam, M, Islam, S, Iso, H, Iwagami, M, Iwu, C, Jaafari, J, Jacobsen, K, Jagnoor, J, Jain, V, Janodia, M, Javaheri, T, Javanmardi, F, Jayaram, S, Jayatilleke, A, Jenabi, E, Jha, R, Ji, J, John, O, Jonas, J, Joo, T, Joseph, N, Joukar, F, Jozwiak, J, Jurisson, M, Kabir, A, Kabir, Z, Kalankesh, L, Kamyari, N, Kanchan, T, Kapoor, N, Karami Matin, B, Karch, A, Karimi, S, Kassahun, G, Kayode, G, Kazemi Karyani, A, Kemmer, L, Khalid, N, Khalilov, R, Khammarnia, M, Khan, E, Khan, G, Khan, M, Khang, Y, Khatab, K, Khater, A, Khater, M, Khayamzadeh, M, Khosravi, A, Kim, D, Kim, Y, Kimokoti, R, Kisa, A, Kisa, S, Kissoon, N, Kopec, J, Kosen, S, Koul, P, Koulmane Laxminarayana, S, Koyanagi, A, Krishan, K, Krishnamoorthy, V, Kuate Defo, B, Kucuk Bicer, B, Kulkarni, V, Kumar, G, Kumar, M, Kumar, N, Kurmi, O, Kusuma, D, La Vecchia, C, Lacey, B, Lalloo, R, Lami, F, Landires, I, Larsson, A, Lasrado, S, Lassi, Z, Lauriola, P, Lee, P, Lee, S, Lee, Y, Leigh, J, Leonardi, M, Lewycka, S, Li, B, Li, S, Liang, J, Lim, L, Limenih, M, Lin, R, Liu, X, Lodha, R, Lopez, A, Lozano, R, Lugo, A, Lunevicius, R, Mackay, M, Madhava Kunjathur, S, Magnani, F, Mahadeshwara Prasad, D, Maheri, M, Mahmoudi, M, Majeed, A, Maled, V, Maleki, A, Maleki, S, Malekzadeh, R, Malik, A, Malta, D, Mamun, A, Mansouri, B, Mansournia, M, Martinez, G, Martini, S, Martins-Melo, F, Masoumi, S, Maulik, P, Mcalinden, C, Mcgrath, J, Medina-Solis, C, Mehrabi Nasab, E, Mejia-Rodriguez, F, Memish, Z, Mendoza, W, Menezes, R, Mengesha, E, Mensah, G, Meretoja, A, Meretoja, T, Mersha, A, Mestrovic, T, Miazgowski, B, Miazgowski, T, Michalek, I, Miller, T, Mini, G, Miri, M, Mirica, A, Mirrakhimov, E, Mirzaei, H, Mirzaei, M, Moazen, B, Moghadaszadeh, M, Mohajer, B, Mohamad, O, Mohammad, Y, Mohammadi, S, Mohammadian-Hafshejani, A, Mohammed, S, Mokdad, A, Molokhia, M, Monasta, L, Mondello, S, Moni, M, Moore, C, Moradi, G, Moradi, M, Moradzadeh, R, Moraga, P, Morawska, L, Morrison, S, Mosser, J, Mousavi Khaneghah, A, Mustafa, G, Naderi, M, Nagarajan, A, Nagaraju, S, Naghavi, M, Naghshtabrizi, B, Naimzada, M, Nangia, V, Narasimha Swamy, S, Nascimento, B, Naveed, M, Nazari, J, Ndejjo, R, Negoi, I, Negoi, R, Nena, E, Nepal, S, Netsere, H, Nguefack-Tsague, G, Ngunjiri, J, Nguyen, C, Nguyen, H, Nigatu, Y, Nigussie, S, Nixon, M, Nnaji, C, Nomura, S, Noor, N, Noubiap, J, Nunez-Samudio, V, Nwatah, V, Oancea, B, Odukoya, O, Ogbo, F, Olusanya, B, Olusanya, J, Omar Bali, A, Onwujekwe, O, Ortiz, A, Otoiu, A, Otstavnov, N, Otstavnov, S, Owolabi, M, P A, M, Padubidri, J, Pakhale, S, Pakshir, K, Pal, P, Palladino, R, Pana, A, Panda-Jonas, S, Pandey, A, Pandi-Perumal, S, Pangaribuan, H, Pardo-Montano, A, Park, E, Patel, S, Patton, G, Pawar, S, Pazoki Toroudi, H, Peden, A, Pepito, V, Peprah, E, Pereira, J, Perez-Gomez, J, Perico, N, Pesudovs, K, Pilgrim, T, Pinheiro, M, Piradov, M, Pirsaheb, M, Platts-Mills, J, Pokhrel, K, Postma, M, Pourjafar, H, Prada, S, Prakash, S, Pupillo, E, Quazi Syed, Z, Rabiee, N, Radfar, A, Rafiee, A, Rafiei, A, Raggi, A, Rahimzadeh, S, Rahman, M, Rahmani, A, Ramezanzadeh, K, Rana, J, Ranabhat, C, Rao, S, Rasella, D, Rastogi, P, Rathi, P, Rawaf, D, Rawaf, S, Rawasia, W, Rawassizadeh, R, Reiner, R, Remuzzi, G, Renzaho, A, Reshmi, B, Resnikoff, S, Rezaei, N, Rezapour, A, Riahi, S, Ribeiro, D, Rickard, J, Roever, L, Ronfani, L, Rothenbacher, D, Rubagotti, E, Rumisha, S, Ryan, P, Saddik, B, Sadeghi, E, Saeedi Moghaddam, S, Sagar, R, Sahebkar, A, Salahshoor, M, Salehi, S, Salem, M, Salimzadeh, H, Salomon, J, Samodra, Y, Samy, A, Sanabria, J, Santric-Milicevic, M, Saraswathy, S, Sarker, A, Sarrafzadegan, N, Sarveazad, A, Sathian, B, Sathish, T, Sattin, D, Saxena, S, Saya, G, Saylan, M, Schiavolin, S, Schlaich, M, Schwebel, D, Schwendicke, F, Senthilkumaran, S, Sepanlou, S, Servan-Mori, E, Sha, F, Shafaat, O, Shahabi, S, Shahbaz, M, Shaheen, A, Shahid, I, Shaikh, M, Shakiba, S, Shalash, A, Shams-Beyranvand, M, Shannawaz, M, Sharafi, K, Sheikh, A, Sheikhbahaei, S, Shiferaw, W, Shigematsu, M, Shin, J, Shiri, R, Shiue, I, Shuval, K, Siddiqi, T, Sidemo, N, Sigfusdottir, I, Sigurvinsdottir, R, Silva, J, Silverberg, J, Simonetti, B, Singh, B, Singh, J, Singhal, D, Sinha, D, Skiadaresi, E, Skryabin, V, Skryabina, A, Sleet, D, Sobaih, B, Sobhiyeh, M, Soltani, S, Soriano, J, Spurlock, E, Sreeramareddy, C, Steiropoulos, P, Stokes, M, Stortecky, S, Sufiyan, M, Suliankatchi Abdulkader, R, Sulo, G, Swope, C, Sykes, B, Szeto, M, Szocska, M, Tabares-Seisdedos, R, Tadesse, E, Taherkhani, A, Tamiru, A, Tareque, M, Tehrani-Banihashemi, A, Temsah, M, Tesfay, F, Tessema, G, Tessema, Z, Thankappan, K, Thapar, R, Tolani, M, Tovani-Palone, M, Traini, E, Tran, B, Tripathy, J, Tsapparellas, G, Tsatsakis, A, Tudor Car, L, Uddin, R, Ullah, A, Umeokonkwo, C, Unim, B, Unnikrishnan, B, Upadhyay, E, Usman, M, Vacante, M, Vaezi, M, Valadan Tahbaz, S, Valdez, P, Vasankari, T, Venketasubramanian, N, Verma, M, Violante, F, Vlassov, V, Vo, B, Vu, G, Wado, Y, Waheed, Y, Wamai, R, Wang, Y, Ward, P, Werdecker, A, Westerman, R, Wickramasinghe, N, Wilner, L, Wiysonge, C, Wu, A, Wu, C, Xie, Y, Yahyazadeh Jabbari, S, Yamagishi, K, Yandrapalli, S, Yaya, S, Yazdi-Feyzabadi, V, Yip, P, Yonemoto, N, Yoon, S, Younis, M, Yousefi, Z, Yousefinezhadi, T, Yu, C, Yusuf, S, Zaidi, S, Zaman, S, Zamani, M, Zamanian, M, Zastrozhin, M, Zastrozhina, A, Zhang, Y, Zhang, Z, Zhao, X, Ziapour, A, Hay, S, Murray, C, Wang, H, Kassebaum, N, and Lee Kong Chian School of Medicine (LKCMedicine)
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Male ,Perinatal care ,Newborn care ,STILLBIRTHS ,RJ101 ,UNDER-5 MORTALITY ,Psychological intervention ,010501 environmental sciences ,Infant mortality ,Global Health ,01 natural sciences ,0302 clinical medicine ,RA0421 ,Cause of Death ,Infant Mortality ,Global health ,Life Tables ,Healthcare improvements ,030212 general & internal medicine ,610 Medicine & health ,Child ,COVID-19 ,Humans ,Infant ,SARS-CoV-2 ,Sustainable Development ,11 Medical and Health Sciences ,Cause of death ,Life Table ,Mortality rate ,1. No poverty ,Public Health, Global Health, Social Medicine and Epidemiology ,General Medicine ,Articles ,Hälsovetenskaper ,Mortality analyses ,3. Good health ,Child, Preschool ,SDG 1 - No Poverty ,Child Mortality ,Female ,Life Sciences & Biomedicine ,Human ,Child mortality ,COUNTRIES ,DEATHS ,Infants -- Mortalitat ,GBD ,03 medical and health sciences ,Medicine, General & Internal ,SDG 3 - Good Health and Well-being ,Life tables ,under-5 mortality rate ,General & Internal Medicine ,Health Sciences ,Neonatal deaths ,medicine ,SYSTEMATIC ANALYSIS ,Medicine [Science] ,Infants -- Salut ,Preschool ,0105 earth and related environmental sciences ,Science & Technology ,Infants nadons -- Salut ,business.industry ,Infants nadons -- Mortalitat ,INFORM ,Infant, Newborn ,Neonatal and child health ,Sustainable Development Goal 3.2 ,GBD 2019 Under-5 Mortality Collaborators ,medicine.disease ,Newborn ,TRENDS ,Sustainable Development Goal ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Deaths ,3121 General medicine, internal medicine and other clinical medicine ,RG ,business ,Systematic Analysis ,Malaria ,Demography - Abstract
Background: Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-19, and a novel framework for quantifying optimal child survival. Methods: We completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated mortality probabilities per 1000 livebirths computed for neonatal mortality rate (NMR) and under-5 mortality rate (U5MR). Scenarios for 2030 represent different potential trajectories, notably including potential effects of the COVID-19 pandemic and the potential impact of improvements preferentially targeting neonatal survival. Optimal child survival metrics were developed by age, sex, and cause of death across all GBD location-years. The first metric is a global optimum and is based on the lowest observed mortality, and the second is a survival potential frontier that is based on stochastic frontier analysis of observed mortality and Healthcare Access and Quality Index. Findings: Global U5MR decreased from 71·2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68·3-74·0) in 2000 to 37·1 (33·2-41·7) in 2019 while global NMR correspondingly declined more slowly from 28·0 deaths per 1000 live births (26·8-29·5) in 2000 to 17·9 (16·3-19·8) in 2019. In 2019, 136 (67%) of 204 countries had a U5MR at or below the SDG 3.2 threshold and 133 (65%) had an NMR at or below the SDG 3.2 threshold, and the reference scenario suggests that by 2030, 154 (75%) of all countries could meet the U5MR targets, and 139 (68%) could meet the NMR targets. Deaths of children younger than 5 years totalled 9·65 million (95% UI 9·05-10·30) in 2000 and 5·05 million (4·27-6·02) in 2019, with the neonatal fraction of these deaths increasing from 39% (3·76 million [95% UI 3·53-4·02]) in 2000 to 48% (2·42 million; 2·06-2·86) in 2019. NMR and U5MR were generally higher in males than in females, although there was no statistically significant difference at the global level. Neonatal disorders remained the leading cause of death in children younger than 5 years in 2019, followed by lower respiratory infections, diarrhoeal diseases, congenital birth defects, and malaria. The global optimum analysis suggests NMR could be reduced to as low as 0·80 (95% UI 0·71-0·86) deaths per 1000 livebirths and U5MR to 1·44 (95% UI 1·27-1·58) deaths per 1000 livebirths, and in 2019, there were as many as 1·87 million (95% UI 1·35-2·58; 37% [95% UI 32-43]) of 5·05 million more deaths of children younger than 5 years than the survival potential frontier. Interpretation: Global child mortality declined by almost half between 2000 and 2019, but progress remains slower in neonates and 65 (32%) of 204 countries, mostly in sub-Saharan Africa and south Asia, are not on track to meet either SDG 3.2 target by 2030. Focused improvements in perinatal and newborn care, continued and expanded delivery of essential interventions such as vaccination and infection prevention, an enhanced focus on equity, continued focus on poverty reduction and education, and investment in strengthening health systems across the development spectrum have the potential to substantially improve U5MR. Given the widespread effects of COVID-19, considerable effort will be required to maintain and accelerate progress. This article was supported by the European Research Council, ERC 848325. Alberto Ortiz was supported by FIS/Fondos FEDER (PI18/01366, PI19/00588, PI19/00815, DTS18/00032, ERA-PerMed-JTC2018 (KIDNEY ATTACK AC18/00064 and PERSTIGAN AC18/00071, ISCIII-RETIC REDinREN RD016/0009). Daniela Ribeiro acknowledges the financial support from the European Union [FEDER funds through COMPETE, POCI-01-0145-FEDER-029253). Joan B Soriano acknowledges support from the Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), Madrid, Spain Funding: Bill & Melinda Gates Foundation
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- 2021
11. The global burden of cancer attributable to risk factors, 2010–19 : A systematic analysis for the Global Burden of Disease Study 2019
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Khanh Bao Tran, Justin J Lang, Kelly Compton, Rixing Xu, Alistair R Acheson, Hannah Jacqueline Henrikson, Jonathan M Kocarnik, Louise Penberthy, Amirali Aali, Qamar Abbas, Behzad Abbasi, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Michael Abdelmasseh, Sherief Abd-Elsalam, Ahmed Abdelwahab Abdelwahab, Gholamreza Abdoli, Hanan Abdulkadir Abdulkadir, Aidin Abedi, Kedir Hussein Abegaz, Hassan Abidi, Richard Gyan Aboagye, Hassan Abolhassani, Abdorrahim Absalan, Yonas Derso Abtew, Hiwa Abubaker Ali, Eman Abu-Gharbieh, Basavaprabhu Achappa, Juan Manuel Acuna, Daniel Addison, Isaac Yeboah Addo, Oyelola A Adegboye, Miracle Ayomikun Adesina, Mohammad Adnan, Qorinah Estiningtyas Sakilah Adnani, Shailesh M Advani, Sumia Afrin, Muhammad Sohail Afzal, Manik Aggarwal, Bright Opoku Ahinkorah, Araz Ramazan Ahmad, Rizwan Ahmad, Sajjad Ahmad, Sohail Ahmad, Sepideh Ahmadi, Haroon Ahmed, Luai A Ahmed, Muktar Beshir Ahmed, Tarik Ahmed Rashid, Wajeeha Aiman, Marjan Ajami, Gizachew Taddesse Akalu, Mostafa Akbarzadeh-Khiavi, Addis Aklilu, Maxwell Akonde, Chisom Joyqueenet Akunna, Hanadi Al Hamad, Fares Alahdab, Fahad Mashhour Alanezi, Turki M Alanzi, Saleh Ali Alessy, Abdelazeem M Algammal, Mohammed Khaled Al-Hanawi, Robert Kaba Alhassan, Beriwan Abdulqadir Ali, Liaqat Ali, Syed Shujait Ali, Yousef Alimohamadi, Vahid Alipour, Syed Mohamed Aljunid, Motasem Alkhayyat, Sadeq Ali Ali Al-Maweri, Sami Almustanyir, Nivaldo Alonso, Shehabaldin Alqalyoobi, Rajaa M Al-Raddadi, Rami H Hani Al-Rifai, Salman Khalifah Al-Sabah, Ala'a B Al-Tammemi, Haya Altawalah, Nelson Alvis-Guzman, Firehiwot Amare, Edward Kwabena Ameyaw, Javad Javad Aminian Dehkordi, Mohammad Hosein Amirzade-Iranaq, Hubert Amu, Ganiyu Adeniyi Amusa, Robert Ancuceanu, Jason A Anderson, Yaregal Animut Animut, Amir Anoushiravani, Ali Arash Anoushirvani, Alireza Ansari-Moghaddam, Mustafa Geleto Ansha, Benny Antony, Maxwell Hubert Antwi, Sumadi Lukman Anwar, Razique Anwer, Anayochukwu Edward Anyasodor, Jalal Arabloo, Morteza Arab-Zozani, Olatunde Aremu, Ayele Mamo Argaw, Hany Ariffin, Timur Aripov, Muhammad Arshad, Al Artaman, Judie Arulappan, Raphael Taiwo Aruleba, Armin Aryannejad, Malke Asaad, Mulusew A Asemahagn, Zatollah Asemi, Mohammad Asghari-Jafarabadi, Tahira Ashraf, Reza Assadi, Mohammad Athar, Seyyed Shamsadin Athari, Maha Moh'd Wahbi Atout, Sameh Attia, Avinash Aujayeb, Marcel Ausloos, Leticia Avila-Burgos, Atalel Fentahun Awedew, Mamaru Ayenew Awoke, Tewachew Awoke, Beatriz Paulina Ayala Quintanilla, Tegegn Mulatu Ayana, Solomon Shitu Ayen, Davood Azadi, Sina Azadnajafabad, Saber Azami-Aghdash, Melkalem Mamuye Azanaw, Mohammadreza Azangou-Khyavy, Amirhossein Azari Jafari, Hosein Azizi, Ahmed Y Y Azzam, Amirhesam Babajani, Muhammad Badar, Ashish D Badiye, Nayereh Baghcheghi, Nader Bagheri, Sara Bagherieh, Saeed Bahadory, Atif Amin Baig, Jennifer L Baker, Ahad Bakhtiari, Ravleen Kaur Bakshi, Maciej Banach, Indrajit Banerjee, Mainak Bardhan, Francesco Barone-Adesi, Fabio Barra, Amadou Barrow, Nasir Z Bashir, Azadeh Bashiri, Saurav Basu, Abdul-Monim Mohammad Batiha, Aeysha Begum, Alehegn Bekele Bekele, Alemayehu Sayih Belay, Melaku Ashagrie Belete, Uzma Iqbal Belgaumi, Arielle Wilder Bell, Luis Belo, Habib Benzian, Alemshet Yirga Berhie, Amiel Nazer C Bermudez, Eduardo Bernabe, Akshaya Srikanth Bhagavathula, Neeraj Bhala, Bharti Bhandari Bhandari, Nikha Bhardwaj, Pankaj Bhardwaj, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja, Soumitra S Bhuyan, Sadia Bibi, Awraris Hailu Bilchut, Bagas Suryo Bintoro, Antonio Biondi, Mesfin Geremaw Birega Birega, Habitu Eshetu Birhan, Tone Bjørge, Oleg Blyuss, Belay Boda Abule Bodicha, Srinivasa Rao Bolla, Archith Boloor, Cristina Bosetti, Dejana Braithwaite, Michael Brauer, Hermann Brenner, Andrey Nikolaevich Briko, Nikolay Ivanovich Briko, Christina Maree Buchanan, Norma B Bulamu, Maria Teresa Bustamante-Teixeira, Muhammad Hammad Butt, Nadeem Shafique Butt, Zahid A Butt, Florentino Luciano Caetano dos Santos, Luis Alberto Cámera, Chao Cao, Yin Cao, Giulia Carreras, Márcia Carvalho, Francieli Cembranel, Ester Cerin, Promit Ananyo Chakraborty, Periklis Charalampous, Vijay Kumar Chattu, Odgerel Chimed-Ochir, Jesus Lorenzo Chirinos-Caceres, Daniel Youngwhan Cho, William C S Cho, Devasahayam J Christopher, Dinh-Toi Chu, Isaac Sunday Chukwu, Aaron J Cohen, Joao Conde, Sandra Cortés, Vera Marisa Costa, Natália Cruz-Martins, Garland T Culbreth, Omid Dadras, Fentaw Teshome Dagnaw, Saad M A Dahlawi, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, Parnaz Daneshpajouhnejad, Anna Danielewicz, An Thi Minh Dao, Reza Darvishi Cheshmeh Soltani, Aso Mohammad Darwesh, Saswati Das, Dragos Virgil Davitoiu, Elham Davtalab Esmaeili, Fernando Pio De la Hoz, Sisay Abebe Debela, Azizallah Dehghan, Biniyam Demisse, Fitsum Wolde Demisse, Edgar Denova-Gutiérrez, Afshin Derakhshani, Meseret Derbew Molla, Diriba Dereje, Kalkidan Solomon Deribe, Rupak Desai, Markos Desalegn Desalegn, Fikadu Nugusu Dessalegn, Samuel Abebe A Dessalegni, Gashaw Dessie, Abebaw Alemayehu Desta, Syed Masudur Rahman Dewan, Samath Dhamminda Dharmaratne, Meghnath Dhimal, Mostafa Dianatinasab, Nancy Diao, Daniel Diaz, Lankamo Ena Digesa, Shilpi Gupta Dixit, Saeid Doaei, Linh Phuong Doan, Paul Narh Doku, Deepa Dongarwar, Wendel Mombaque dos Santos, Tim Robert Driscoll, Haneil Larson Dsouza, Oyewole Christopher Durojaiye, Sareh Edalati, Fatemeh Eghbalian, Elham Ehsani-Chimeh, Ebrahim Eini, Michael Ekholuenetale, Temitope Cyrus Ekundayo, Donatus U Ekwueme, Maha El Tantawi, Mostafa Ahmed Elbahnasawy, Iffat Elbarazi, Hesham Elghazaly, Muhammed Elhadi, Waseem El-Huneidi, Mohammad Hassan Emamian, Luchuo Engelbert Bain, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Tegegne Eshetu, Babak Eshrati, Sharareh Eskandarieh, Juan Espinosa-Montero, Farshid Etaee, Azin Etemadimanesh, Tahir Eyayu, Ifeanyi Jude Ezeonwumelu, Sayeh Ezzikouri, Adeniyi Francis Fagbamigbe, Saman Fahimi, Ildar Ravisovich Fakhradiyev, Emerito Jose A Faraon, Jawad Fares, Abbas Farmany, Umar Farooque, Hossein Farrokhpour, Abidemi Omolara Fasanmi, Ali Fatehizadeh, Wafa Fatima, Hamed Fattahi, Ginenus Fekadu, Berhanu Elfu Feleke, Allegra Allegra Ferrari, Simone Ferrero, Lorenzo Ferro Desideri, Irina Filip, Florian Fischer, Roham Foroumadi, Masoud Foroutan, Takeshi Fukumoto, Peter Andras Gaal, Mohamed M Gad, Muktar A Gadanya, Abduzhappar Gaipov, Nasrin Galehdar, Silvano Gallus, Tushar Garg, Mariana Gaspar Fonseca, Yosef Haile Gebremariam, Teferi Gebru Gebremeskel, Mathewos Alemu Gebremichael, Yohannes Fikadu Geda, Yibeltal Yismaw Gela, Belete Negese Belete Gemeda, Melaku Getachew, Motuma Erena Getachew, Kazem Ghaffari, Mansour Ghafourifard, Seyyed-Hadi Ghamari, Mohammad Ghasemi Nour, Fariba Ghassemi, Ajnish Ghimire, Nermin Ghith, Maryam Gholamalizadeh, Jamshid Gholizadeh Navashenaq, Sherief Ghozy, Syed Amir Gilani, Paramjit Singh Gill, Themba G Ginindza, Abraham Tamirat T Gizaw, James C Glasbey, Justyna Godos, Amit Goel, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Mohamad Golitaleb, Giuseppe Gorini, Bárbara Niegia Garcia Goulart, Giuseppe Grosso, Habtamu Alganeh Guadie, Mohammed Ibrahim Mohialdeen Gubari, Temesgen Worku Gudayu, Maximiliano Ribeiro Guerra, Damitha Asanga Gunawardane, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Mekdes Kondale Gurara, Alemu Guta, Parham Habibzadeh, Atlas Haddadi Avval, Nima Hafezi-Nejad, Adel Hajj Ali, Arvin Haj-Mirzaian, Esam S Halboub, Aram Halimi, Rabih Halwani, Randah R Hamadeh, Sajid Hameed, Samer Hamidi, Asif Hanif, Sanam Hariri, Netanja I Harlianto, Josep Maria Haro, Risky Kusuma Hartono, Ahmed I Hasaballah, S M Mahmudul Hasan, Hamidreza Hasani, Seyedeh Melika Hashemi, Abbas M Hassan, Soheil Hassanipour, Khezar Hayat, Golnaz Heidari, Mohammad Heidari, Zahra Heidarymeybodi, Brenda Yuliana Herrera-Serna, Claudiu Herteliu, Kamal Hezam, Yuta Hiraike, Mbuzeleni Mbuzeleni Hlongwa, Ramesh Holla, Marianne Holm, Nobuyuki Horita, Mohammad Hoseini, Md Mahbub Hossain, Mohammad Bellal Hossain Hossain, Mohammad-Salar Hosseini, Ali Hosseinzadeh, Mehdi Hosseinzadeh, Mihaela Hostiuc, Sorin Hostiuc, Mowafa Househ, Junjie Huang, Fernando N Hugo, Ayesha Humayun, Salman Hussain, Nawfal R Hussein, Bing-Fang Hwang, Segun Emmanuel Ibitoye, Pulwasha Maria Iftikhar, Kevin S Ikuta, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Mustapha Immurana, Kaire Innos, Pooya Iranpour, Lalu Muhammad Irham, Md Shariful Islam, Rakibul M Islam, Farhad Islami, Nahlah Elkudssiah Ismail, Gaetano Isola, Masao Iwagami, Linda Merin J, Abhishek Jaiswal, Mihajlo Jakovljevic, Mahsa Jalili, Shahram Jalilian, Elham Jamshidi, Sung-In Jang, Chinmay T Jani, Tahereh Javaheri, Umesh Umesh Jayarajah, Shubha Jayaram, Seyed Behzad Jazayeri, Rime Jebai, Bedru Jemal, Wonjeong Jeong, Ravi Prakash Jha, Har Ashish Jindal, Yetunde O John-Akinola, Jost B Jonas, Tamas Joo, Nitin Joseph, Farahnaz Joukar, Jacek Jerzy Jozwiak, Mikk Jürisson, Ali Kabir, Salah Eddine Oussama Kacimi, Vidya Kadashetti, Farima Kahe, Pradnya Vishal Kakodkar, Laleh R Kalankesh, Leila R Kalankesh, Rohollah Kalhor, Vineet Kumar Kamal, Farin Kamangar, Ashwin Kamath, Tanuj Kanchan, Eswar Kandaswamy, Himal Kandel, HyeJung Kang, Girum Gebremeskel Kanno, Neeti Kapoor, Sitanshu Sekhar Kar, Shama D Karanth, Ibraheem M Karaye, André Karch, Amirali Karimi, Bekalu Getnet Kassa, Patrick DMC Katoto, Joonas H Kauppila, Harkiran Kaur, Abinet Gebremickael Kebede, Leila Keikavoosi-Arani, Gemechu Gemechu Kejela, Phillip M Kemp Bohan, Maryam Keramati, Mohammad Keykhaei, Himanshu Khajuria, Abbas Khan, Abdul Aziz Khan Khan, Ejaz Ahmad Khan, Gulfaraz Khan, Md Nuruzzaman Khan, Moien AB Khan, Javad Khanali, Khaled Khatab, Moawiah Mohammad Khatatbeh, Mahalaqua Nazli Khatib, Maryam Khayamzadeh, Hamid Reza Khayat Kashani, Mohammad Amin Khazeei Tabari, Mehdi Khezeli, Mahmoud Khodadost, Min Seo Kim, Yun Jin Kim, Adnan Kisa, Sezer Kisa, Miloslav Klugar, Jitka Klugarová, Ali-Asghar Kolahi, Pavel Kolkhir, Farzad Kompani, Parvaiz A Koul, Sindhura Lakshmi Koulmane Laxminarayana, Ai Koyanagi, Kewal Krishan, Yuvaraj Krishnamoorthy, Burcu Kucuk Bicer, Nuworza Kugbey, Mukhtar Kulimbet, Akshay Kumar, G Anil Kumar, Narinder Kumar, Om P Kurmi, Ambily Kuttikkattu, Carlo La Vecchia, Arista Lahiri, Dharmesh Kumar Lal, Judit Lám, Qing Lan, Iván Landires, Bagher Larijani, Savita Lasrado, Jerrald Lau, Paolo Lauriola, Caterina Ledda, Sang-woong Lee, Shaun Wen Huey Lee, Wei-Chen Lee, Yeong Yeh Lee, Yo Han Lee, Samson Mideksa Legesse, James Leigh, Elvynna Leong, Ming-Chieh Li, Stephen S Lim, Gang Liu, Jue Liu, Chun-Han Lo, Ayush Lohiya, Platon D Lopukhov, László Lorenzovici, Mojgan Lotfi, Joana A Loureiro, Raimundas Lunevicius, Farzan Madadizadeh, Ahmad R Mafi, Sameh Magdeldin, Soleiman Mahjoub, Ata Mahmoodpoor, Morteza Mahmoudi, Marzieh Mahmoudimanesh, Rashidul Alam Mahumud, Azeem Majeed, Jamal Majidpoor, Alaa Makki, Konstantinos Christos Makris, Elaheh Malakan Rad, Mohammad-Reza Malekpour, Reza Malekzadeh, Ahmad Azam Malik, Tauqeer Hussain Mallhi, Sneha Deepak Mallya, Mohammed A Mamun, Ana Laura Manda, Fariborz Mansour-Ghanaei, Borhan Mansouri, Mohammad Ali Mansournia, Lorenzo Giovanni Mantovani, Santi Martini, Miquel Martorell, Sahar Masoudi, Seyedeh Zahra Masoumi, Clara N Matei, Elezebeth Mathews, Manu Raj Mathur, Vasundhara Mathur, Martin McKee, Jitendra Kumar Meena, Khalid Mehmood, Entezar Mehrabi Nasab, Ravi Mehrotra, Addisu Melese, Walter Mendoza, Ritesh G Menezes, SIsay Derso Mengesha, Laverne G Mensah, Alexios-Fotios A Mentis, Andry Yasmid Mera Mera-Mamián, Tuomo J Meretoja, Mehari Woldemariam Merid, Amanual Getnet Mersha, Belsity Temesgen Meselu, Mahboobeh Meshkat, Tomislav Mestrovic, Junmei Miao Jonasson, Tomasz Miazgowski, Irmina Maria Michalek, Gelana Fekadu Worku Mijena, Ted R Miller, Shabir Ahmad Mir, Seyed Kazem Mirinezhad, Seyyedmohammadsadeq Mirmoeeni, Mohammad Mirza-Aghazadeh-Attari, Hamed Mirzaei, Hamid Reza Mirzaei, Abay Sisay Misganaw, Sanjeev Misra, Karzan Abdulmuhsin Mohammad, Esmaeil Mohammadi, Mokhtar Mohammadi, Abdollah Mohammadian-Hafshejani, Reza Mohammadpourhodki, Arif Mohammed, Shafiu Mohammed, Syam Mohan, Mohammad Mohseni, Nagabhishek Moka, Ali H Mokdad, Alex Molassiotis, Mariam Molokhia, Kaveh Momenzadeh, Sara Momtazmanesh, Lorenzo Monasta, Ute Mons, Ahmed Al Montasir, Fateme Montazeri, Arnulfo Montero, Mohammad Amin Moosavi, Abdolvahab Moradi, Yousef Moradi, Mostafa Moradi Sarabi, Paula Moraga, Lidia Morawska, Shane Douglas Morrison, Jakub Morze, Abbas Mosapour, Ebrahim Mostafavi, Seyyed Meysam Mousavi, Haleh Mousavi Isfahani, Amin Mousavi Khaneghah, Christine Mpundu-Kaambwa, Sumaira Mubarik, Francesk Mulita, Daniel Munblit, Sandra B Munro, Efrén Murillo-Zamora, Jonah Musa, Ashraf F Nabhan, Ahamarshan Jayaraman Nagarajan, Shankar Prasad Nagaraju, Gabriele Nagel, Mohammadreza Naghipour, Mukhammad David Naimzada, Tapas Sadasivan Nair, Atta Abbas Naqvi, Sreenivas Narasimha Swamy, Aparna Ichalangod Narayana, Hasan Nassereldine, Zuhair S Natto, Biswa Prakash Nayak, Rawlance Ndejjo, Sabina Onyinye Nduaguba, Wogene Wogene Negash, Seyed Aria Nejadghaderi, Kazem Nejati, Sandhya Neupane Kandel, Huy Van Nguyen Nguyen, Robina Khan Niazi, Nurulamin M Noor, Maryam Noori, Nafise Noroozi, Hasti Nouraei, Ali Nowroozi, Virginia Nuñez-Samudio, Chimezie Igwegbe Nzoputam, Ogochukwu Janet Nzoputam, Bogdan Oancea, Oluwakemi Ololade Odukoya, Onome Bright Oghenetega, Ropo Ebenezer Ogunsakin, Ayodipupo Sikiru Oguntade, In-Hwan Oh, Hassan Okati-Aliabad, Akinkunmi Paul Okekunle, Andrew T Olagunju, Tinuke O Olagunju, Babayemi Oluwaseun Olakunde, Isaac Iyinoluwa Olufadewa, Emad Omer, Abidemi E Emmanuel Omonisi, Sokking Ong, Obinna E Onwujekwe, Hans Orru, Stanislav S Otstavnov, Abderrahim Oulhaj, Bilcha Oumer, Oluwatomi Funbi Owopetu, Babatunji Emmanuel Oyinloye, Mahesh P A, Alicia Padron-Monedero, Jagadish Rao Padubidri, Babak Pakbin, Keyvan Pakshir, Reza Pakzad, Tamás Palicz, Adrian Pana, Anamika Pandey, Ashok Pandey, Suman Pant, Shahina Pardhan, Eun-Cheol Park, Eun-Kee Park, Seoyeon Park, Jay Patel, Siddhartha Pati, Rajan Paudel, Uttam Paudel, Mihaela Paun, Hamidreza Pazoki Toroudi, Minjin Peng, Jeevan Pereira, Renato B Pereira, Simone Perna, Navaraj Perumalsamy, Richard G Pestell, Raffaele Pezzani, Cristiano Piccinelli, Julian David Pillay, Zahra Zahid Piracha, Tobias Pischon, Maarten J Postma, Ashkan Pourabhari Langroudi, Akram Pourshams, Naeimeh Pourtaheri, Akila Prashant, Mirza Muhammad Fahd Qadir, Zahiruddin Quazi Syed, Mohammad Rabiee, Navid Rabiee, Amir Radfar, Raghu Anekal Radhakrishnan, Venkatraman Radhakrishnan, Mojtaba Raeisi, Ata Rafiee, Alireza Rafiei, Nasiru Raheem, Fakher Rahim, Md Obaidur Rahman, Mosiur Rahman, Muhammad Aziz Rahman, Amir Masoud Rahmani, Shayan Rahmani, Vahid Rahmanian, Nazanin Rajai, Aashish Rajesh, Pradhum Ram, Kiana Ramezanzadeh, Juwel Rana, Kamal Ranabhat, Priyanga Ranasinghe, Chythra R Rao, Sowmya J Rao, Sina Rashedi, Amirfarzan Rashidi, Mahsa Rashidi, Mohammad-Mahdi Rashidi, Zubair Ahmed Ratan, David Laith Rawaf, Salman Rawaf, Lal Rawal, Reza Rawassizadeh, Mohammad Sadegh Razeghinia, Ashfaq Ur Rehman, Inayat ur Rehman, Marissa B Reitsma, Andre M N Renzaho, Maryam Rezaei, Nazila Rezaei, Negar Rezaei, Nima Rezaei, Saeid Rezaei, Mohsen Rezaeian, Aziz Rezapour, Abanoub Riad, Reza Rikhtegar, Maria Rios-Blancas, Thomas J Roberts, Peter Rohloff, Esperanza Romero-Rodríguez, Gholamreza Roshandel, Godfrey M Rwegerera, Manjula S, Maha Mohamed Saber-Ayad, Bahar Saberzadeh-Ardestani, Siamak Sabour, Basema Saddik, Erfan Sadeghi, Mohammad Reza Saeb, Umar Saeed, Mohsen Safaei, Azam Safary, Maryam Sahebazzamani, Amirhossein Sahebkar, Harihar Sahoo, Mirza Rizwan Sajid, Hedayat Salari, Sana Salehi, Marwa Rashad Salem, Hamideh Salimzadeh, Yoseph Leonardo Samodra, Abdallah M Samy, Juan Sanabria, Senthilkumar Sankararaman, Francesco Sanmarchi, Milena M Santric-Milicevic, Muhammad Arif Nadeem Saqib, Arash Sarveazad, Fatemeh Sarvi, Brijesh Sathian, Maheswar Satpathy, Nicolas Sayegh, Ione Jayce Ceola Schneider, Michaël Schwarzinger, Mario Šekerija, Subramanian Senthilkumaran, Sadaf G Sepanlou, Allen Seylani, Kenbon Seyoum, Feng Sha, Omid Shafaat, Pritik A Shah, Saeed Shahabi, Izza Shahid, Mohammad Amin Shahrbaf, Hamid R Shahsavari, Masood Ali Shaikh, Mohammed Feyisso Shaka, Elaheh Shaker, Mohammed Shannawaz, Mequannent Melaku Sharew Sharew, Azam Sharifi, Javad Sharifi-Rad, Purva Sharma, Bereket Beyene Shashamo, Aziz Sheikh, Mahdi Sheikh, Sara Sheikhbahaei, Rahim Ali Sheikhi, Ali Sheikhy, Peter Robin Shepherd, Adithi Shetty, Jeevan K Shetty, Ranjitha S Shetty, Kenji Shibuya, Reza Shirkoohi, Hesamaddin Shirzad-Aski, K M Shivakumar, Siddharudha Shivalli, Velizar Shivarov, Parnian Shobeiri, Zahra Shokri Varniab, Seyed Afshin Shorofi, Sunil Shrestha, Migbar Mekonnen Sibhat, Sudeep K Siddappa Malleshappa, Negussie Boti Sidemo, Diego Augusto Santos Silva, Luís Manuel Lopes Rodrigues Silva, Guilherme Silva Julian, Nicola Silvestris, Wudneh Simegn, Achintya Dinesh Singh, Ambrish Singh, Garima Singh, Harpreet Singh, Jasvinder A Singh, Jitendra Kumar Singh, Paramdeep Singh, Surjit Singh, Dhirendra Narain Sinha, Abiy H Sinke, Md Shahjahan Siraj, Freddy Sitas, Samarjeet Singh Siwal, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Bogdan Socea, Matthew J Soeberg, Ahmad Sofi-Mahmudi, Yonatan Solomon, Mohammad Sadegh Soltani-Zangbar, Suhang Song, Yimeng Song, Reed J D Sorensen, Sergey Soshnikov, Houman Sotoudeh, Alieu Sowe, Mu'awiyyah Babale Sufiyan, Ryan Suk, Muhammad Suleman, Rizwan Suliankatchi Abdulkader, Saima Sultana, Daniel Sur, Miklós Szócska, Seidamir Pasha Tabaeian, Rafael Tabarés-Seisdedos, Seyyed Mohammad Tabatabaei, Takahiro Tabuchi, Hooman Tadbiri, Ensiyeh Taheri, Majid Taheri, Moslem Taheri Soodejani, Ken Takahashi, Iman M Talaat, Mircea Tampa, Ker-Kan Tan, Nathan Y Tat, Vivian Y Tat, Ahmad Tavakoli, Arash Tavakoli, Arash Tehrani-Banihashemi, Yohannes Tekalegn, Fisaha Haile Tesfay, Rekha Thapar, Aravind Thavamani, Viveksandeep Thoguluva Chandrasekar, Nihal Thomas, Nikhil Kenny Thomas, Jansje Henny Vera Ticoalu, Amir Tiyuri, Daniel Nigusse Tollosa, Roman Topor-Madry, Mathilde Touvier, Marcos Roberto Tovani-Palone, Eugenio Traini, Mai Thi Ngoc Tran, Jaya Prasad Tripathy, Gebresilasea Gendisha Ukke, Irfan Ullah, Saif Ullah, Sana Ullah, Bhaskaran Unnikrishnan, Marco Vacante, Maryam Vaezi, Sahel Valadan Tahbaz, Pascual R Valdez, Constantine Vardavas, Shoban Babu Varthya, Siavash Vaziri, Diana Zuleika Velazquez, Massimiliano Veroux, Paul J Villeneuve, Francesco S Violante, Sergey Konstantinovitch Vladimirov, Vasily Vlassov, Bay Vo, Linh Gia Vu, Abdul Wadood Wadood, Yasir Waheed, Mandaras Tariku Walde, Richard G Wamai, Cong Wang, Fang Wang, Ning Wang, Yu Wang, Paul Ward, Abdul Waris, Ronny Westerman, Nuwan Darshana Wickramasinghe, Melat Woldemariam, Berhanu Woldu, Hong Xiao, Suowen Xu, Xiaoyue Xu, Lalit Yadav, Seyed Hossein Yahyazadeh Jabbari, Lin Yang, Fereshteh Yazdanpanah, Yigizie Yeshaw, Yazachew Yismaw, Naohiro Yonemoto, Mustafa Z Younis, Zabihollah Yousefi, Fatemeh Yousefian, Chuanhua Yu, Yong Yu, Ismaeel Yunusa, Mazyar Zahir, Nazar Zaki, Burhan Abdullah Zaman, Moein Zangiabadian, Fariba Zare, Iman Zare, Zahra Zareshahrabadi, Armin Zarrintan, Mikhail Sergeevich Zastrozhin, Mohammad A Zeineddine, Dongyu Zhang, Jianrong Zhang, Yunquan Zhang, Zhi-Jiang Zhang, Linghui Zhou, Sanjay Zodpey, Mohammad Zoladl, Theo Vos, Simon I Hay, Lisa M Force, Christopher J L Murray, Helsinki University Hospital Area, HUS Comprehensive Cancer Center, Tran, K, Lang, J, Compton, K, Xu, R, Acheson, A, Henrikson, H, Kocarnik, J, Penberthy, L, Aali, A, Abbas, Q, Abbasi, B, Abbasi-Kangevari, M, Abbasi-Kangevari, Z, Abbastabar, H, Abdelmasseh, M, Abd-Elsalam, S, Abdelwahab, A, Abdoli, G, Abdulkadir, H, Abedi, A, Abegaz, K, Abidi, H, Aboagye, R, Abolhassani, H, Absalan, A, Abtew, Y, Abubaker Ali, H, Abu-Gharbieh, E, Achappa, B, Acuna, J, Addison, D, Addo, I, Adegboye, O, Adesina, M, Adnan, M, Adnani, Q, Advani, S, Afrin, S, Afzal, M, Aggarwal, M, Ahinkorah, B, Ahmad, A, Ahmad, R, Ahmad, S, Ahmadi, S, Ahmed, H, Ahmed, L, Ahmed, M, Ahmed Rashid, T, Aiman, W, Ajami, M, Akalu, G, Akbarzadeh-Khiavi, M, Aklilu, A, Akonde, M, Akunna, C, Al Hamad, H, Alahdab, F, Alanezi, F, Alanzi, T, Alessy, S, Algammal, A, Al-Hanawi, M, Alhassan, R, Ali, B, Ali, L, Ali, S, Alimohamadi, Y, Alipour, V, Aljunid, S, Alkhayyat, M, Al-Maweri, S, Almustanyir, S, Alonso, N, Alqalyoobi, S, Al-Raddadi, R, Al-Rifai, R, Al-Sabah, S, Al-Tammemi, A, Altawalah, H, Alvis-Guzman, N, Amare, F, Ameyaw, E, Aminian Dehkordi, J, Amirzade-Iranaq, M, Amu, H, Amusa, G, Ancuceanu, R, Anderson, J, Animut, Y, Anoushiravani, A, Anoushirvani, A, Ansari-Moghaddam, A, Ansha, M, Antony, B, Antwi, M, Anwar, S, Anwer, R, Anyasodor, A, Arabloo, J, Arab-Zozani, M, Aremu, O, Argaw, A, Ariffin, H, Aripov, T, Arshad, M, Artaman, A, Arulappan, J, Aruleba, R, Aryannejad, A, Asaad, M, Asemahagn, M, Asemi, Z, Asghari-Jafarabadi, M, Ashraf, T, Assadi, R, Athar, M, Athari, S, Atout, M, Attia, S, Aujayeb, A, Ausloos, M, Avila-Burgos, L, Awedew, A, Awoke, M, Awoke, T, Ayala Quintanilla, B, Ayana, T, Ayen, S, Azadi, D, Azadnajafabad, S, Azami-Aghdash, S, Azanaw, M, Azangou-Khyavy, M, Azari Jafari, A, Azizi, H, Azzam, A, Babajani, A, Badar, M, Badiye, A, Baghcheghi, N, Bagheri, N, Bagherieh, S, Bahadory, S, Baig, A, Baker, J, Bakhtiari, A, Bakshi, R, Banach, M, Banerjee, I, Bardhan, M, Barone-Adesi, F, Barra, F, Barrow, A, Bashir, N, Bashiri, A, Basu, S, Batiha, A, Begum, A, Bekele, A, Belay, A, Belete, M, Belgaumi, U, Bell, A, Belo, L, Benzian, H, Berhie, A, Bermudez, A, Bernabe, E, Bhagavathula, A, Bhala, N, Bhandari, B, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bhojaraja, V, Bhuyan, S, Bibi, S, Bilchut, A, Bintoro, B, Biondi, A, Birega, M, Birhan, H, Bjorge, T, Blyuss, O, Bodicha, B, Bolla, S, Boloor, A, Bosetti, C, Braithwaite, D, Brauer, M, Brenner, H, Briko, A, Briko, N, Buchanan, C, Bulamu, N, Bustamante-Teixeira, M, Butt, M, Butt, N, Butt, Z, Caetano dos Santos, F, Camera, L, Cao, C, Cao, Y, Carreras, G, Carvalho, M, Cembranel, F, Cerin, E, Chakraborty, P, Charalampous, P, Chattu, V, Chimed-Ochir, O, Chirinos-Caceres, J, Cho, D, Cho, W, Christopher, D, Chu, D, Chukwu, I, Cohen, A, Conde, J, Cortes, S, Costa, V, Cruz-Martins, N, Culbreth, G, Dadras, O, Dagnaw, F, Dahlawi, S, Dai, X, Dandona, L, Dandona, R, Daneshpajouhnejad, P, Danielewicz, A, Dao, A, Darvishi Cheshmeh Soltani, R, Darwesh, A, Das, S, Davitoiu, D, Davtalab Esmaeili, E, De la Hoz, F, Debela, S, Dehghan, A, Demisse, B, Demisse, F, Denova-Gutierrez, E, Derakhshani, A, Derbew Molla, M, Dereje, D, Deribe, K, Desai, R, Desalegn, M, Dessalegn, F, Dessalegni, S, Dessie, G, Desta, A, Dewan, S, Dharmaratne, S, Dhimal, M, Dianatinasab, M, Diao, N, Diaz, D, Digesa, L, Dixit, S, Doaei, S, Doan, L, Doku, P, Dongarwar, D, dos Santos, W, Driscoll, T, Dsouza, H, Durojaiye, O, Edalati, S, Eghbalian, F, Ehsani-Chimeh, E, Eini, E, Ekholuenetale, M, Ekundayo, T, Ekwueme, D, El Tantawi, M, Elbahnasawy, M, Elbarazi, I, Elghazaly, H, Elhadi, M, El-Huneidi, W, Emamian, M, Engelbert Bain, L, Enyew, D, Erkhembayar, R, Eshetu, T, Eshrati, B, Eskandarieh, S, Espinosa-Montero, J, Etaee, F, Etemadimanesh, A, Eyayu, T, Ezeonwumelu, I, Ezzikouri, S, Fagbamigbe, A, Fahimi, S, Fakhradiyev, I, Faraon, E, Fares, J, Farmany, A, Farooque, U, Farrokhpour, H, Fasanmi, A, Fatehizadeh, A, Fatima, W, Fattahi, H, Fekadu, G, Feleke, B, Ferrari, A, Ferrero, S, Ferro Desideri, L, Filip, I, Fischer, F, Foroumadi, R, Foroutan, M, Fukumoto, T, Gaal, P, Gad, M, Gadanya, M, Gaipov, A, Galehdar, N, Gallus, S, Garg, T, Gaspar Fonseca, M, Gebremariam, Y, Gebremeskel, T, Gebremichael, M, Geda, Y, Gela, Y, Gemeda, B, Getachew, M, Ghaffari, K, Ghafourifard, M, Ghamari, S, Ghasemi Nour, M, Ghassemi, F, Ghimire, A, Ghith, N, Gholamalizadeh, M, Gholizadeh Navashenaq, J, Ghozy, S, Gilani, S, Gill, P, Ginindza, T, Gizaw, A, Glasbey, J, Godos, J, Goel, A, Golechha, M, Goleij, P, Golinelli, D, Golitaleb, M, Gorini, G, Goulart, B, Grosso, G, Guadie, H, Gubari, M, Gudayu, T, Guerra, M, Gunawardane, D, Gupta, B, Gupta, S, Gupta, V, Gurara, M, Guta, A, Habibzadeh, P, Haddadi Avval, A, Hafezi-Nejad, N, Hajj Ali, A, Haj-Mirzaian, A, Halboub, E, Halimi, A, Halwani, R, Hamadeh, R, Hameed, S, Hamidi, S, Hanif, A, Hariri, S, Harlianto, N, Haro, J, Hartono, R, Hasaballah, A, Hasan, S, Hasani, H, Hashemi, S, Hassan, A, Hassanipour, S, Hayat, K, Heidari, G, Heidari, M, Heidarymeybodi, Z, Herrera-Serna, B, Herteliu, C, Hezam, K, Hiraike, Y, Hlongwa, M, Holla, R, Holm, M, Horita, N, Hoseini, M, Hossain, M, Hosseini, M, Hosseinzadeh, A, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Huang, J, Hugo, F, Humayun, A, Hussain, S, Hussein, N, Hwang, B, Ibitoye, S, Iftikhar, P, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Immurana, M, Innos, K, Iranpour, P, Irham, L, Islam, M, Islam, R, Islami, F, Ismail, N, Isola, G, Iwagami, M, J, L, Jaiswal, A, Jakovljevic, M, Jalili, M, Jalilian, S, Jamshidi, E, Jang, S, Jani, C, Javaheri, T, Jayarajah, U, Jayaram, S, Jazayeri, S, Jebai, R, Jemal, B, Jeong, W, Jha, R, Jindal, H, John-Akinola, Y, Jonas, J, Joo, T, Joseph, N, Joukar, F, Jozwiak, J, Jurisson, M, Kabir, A, Kacimi, S, Kadashetti, V, Kahe, F, Kakodkar, P, Kalankesh, L, Kalhor, R, Kamal, V, Kamangar, F, Kamath, A, Kanchan, T, Kandaswamy, E, Kandel, H, Kang, H, Kanno, G, Kapoor, N, Kar, S, Karanth, S, Karaye, I, Karch, A, Karimi, A, Kassa, B, Katoto, P, Kauppila, J, Kaur, H, Kebede, A, Keikavoosi-Arani, L, Kejela, G, Kemp Bohan, P, Keramati, M, Keykhaei, M, Khajuria, H, Khan, A, Khan, E, Khan, G, Khan, M, Khanali, J, Khatab, K, Khatatbeh, M, Khatib, M, Khayamzadeh, M, Khayat Kashani, H, Khazeei Tabari, M, Khezeli, M, Khodadost, M, Kim, M, Kim, Y, Kisa, A, Kisa, S, Klugar, M, Klugarova, J, Kolahi, A, Kolkhir, P, Kompani, F, Koul, P, Koulmane Laxminarayana, S, Koyanagi, A, Krishan, K, Krishnamoorthy, Y, Kucuk Bicer, B, Kugbey, N, Kulimbet, M, Kumar, A, Kumar, G, Kumar, N, Kurmi, O, Kuttikkattu, A, La Vecchia, C, Lahiri, A, Lal, D, Lam, J, Lan, Q, Landires, I, Larijani, B, Lasrado, S, Lau, J, Lauriola, P, Ledda, C, Lee, S, Lee, W, Lee, Y, Legesse, S, Leigh, J, Leong, E, Li, M, Lim, S, Liu, G, Liu, J, Lo, C, Lohiya, A, Lopukhov, P, Lorenzovici, L, Lotfi, M, Loureiro, J, Lunevicius, R, Madadizadeh, F, Mafi, A, Magdeldin, S, Mahjoub, S, Mahmoodpoor, A, Mahmoudi, M, Mahmoudimanesh, M, Mahumud, R, Majeed, A, Majidpoor, J, Makki, A, Makris, K, Malakan Rad, E, Malekpour, M, Malekzadeh, R, Malik, A, Mallhi, T, Mallya, S, Mamun, M, Manda, A, Mansour-Ghanaei, F, Mansouri, B, Mansournia, M, Mantovani, L, Martini, S, Martorell, M, Masoudi, S, Masoumi, S, Matei, C, Mathews, E, Mathur, M, Mathur, V, Mckee, M, Meena, J, Mehmood, K, Mehrabi Nasab, E, Mehrotra, R, Melese, A, Mendoza, W, Menezes, R, Mengesha, S, Mensah, L, Mentis, A, Mera-Mamian, A, Meretoja, T, Merid, M, Mersha, A, Meselu, B, Meshkat, M, Mestrovic, T, Miao Jonasson, J, Miazgowski, T, Michalek, I, Mijena, G, Miller, T, Mir, S, Mirinezhad, S, Mirmoeeni, S, Mirza-Aghazadeh-Attari, M, Mirzaei, H, Misganaw, A, Misra, S, Mohammad, K, Mohammadi, E, Mohammadi, M, Mohammadian-Hafshejani, A, Mohammadpourhodki, R, Mohammed, A, Mohammed, S, Mohan, S, Mohseni, M, Moka, N, Mokdad, A, Molassiotis, A, Molokhia, M, Momenzadeh, K, Momtazmanesh, S, Monasta, L, Mons, U, Montasir, A, Montazeri, F, Montero, A, Moosavi, M, Moradi, A, Moradi, Y, Moradi Sarabi, M, Moraga, P, Morawska, L, Morrison, S, Morze, J, Mosapour, A, Mostafavi, E, Mousavi, S, Mousavi Isfahani, H, Mousavi Khaneghah, A, Mpundu-Kaambwa, C, Mubarik, S, Mulita, F, Munblit, D, Munro, S, Murillo-Zamora, E, Musa, J, Nabhan, A, Nagarajan, A, Nagaraju, S, Nagel, G, Naghipour, M, Naimzada, M, Nair, T, Naqvi, A, Narasimha Swamy, S, Narayana, A, Nassereldine, H, Natto, Z, Nayak, B, Ndejjo, R, Nduaguba, S, Negash, W, Nejadghaderi, S, Nejati, K, Neupane Kandel, S, Nguyen, H, Niazi, R, Noor, N, Noori, M, Noroozi, N, Nouraei, H, Nowroozi, A, Nunez-Samudio, V, Nzoputam, C, Nzoputam, O, Oancea, B, Odukoya, O, Oghenetega, O, Ogunsakin, R, Oguntade, A, Oh, I, Okati-Aliabad, H, Okekunle, A, Olagunju, A, Olagunju, T, Olakunde, B, Olufadewa, I, Omer, E, Omonisi, A, Ong, S, Onwujekwe, O, Orru, H, Otstavnov, S, Oulhaj, A, Oumer, B, Owopetu, O, Oyinloye, B, P A, M, Padron-Monedero, A, Padubidri, J, Pakbin, B, Pakshir, K, Pakzad, R, Palicz, T, Pana, A, Pandey, A, Pant, S, Pardhan, S, Park, E, Park, S, Patel, J, Pati, S, Paudel, R, Paudel, U, Paun, M, Pazoki Toroudi, H, Peng, M, Pereira, J, Pereira, R, Perna, S, Perumalsamy, N, Pestell, R, Pezzani, R, Piccinelli, C, Pillay, J, Piracha, Z, Pischon, T, Postma, M, Pourabhari Langroudi, A, Pourshams, A, Pourtaheri, N, Prashant, A, Qadir, M, Quazi Syed, Z, Rabiee, M, Rabiee, N, Radfar, A, Radhakrishnan, R, Radhakrishnan, V, Raeisi, M, Rafiee, A, Rafiei, A, Raheem, N, Rahim, F, Rahman, M, Rahmani, A, Rahmani, S, Rahmanian, V, Rajai, N, Rajesh, A, Ram, P, Ramezanzadeh, K, Rana, J, Ranabhat, K, Ranasinghe, P, Rao, C, Rao, S, Rashedi, S, Rashidi, A, Rashidi, M, Ratan, Z, Rawaf, D, Rawaf, S, Rawal, L, Rawassizadeh, R, Razeghinia, M, Rehman, A, Rehman, I, Reitsma, M, Renzaho, A, Rezaei, M, Rezaei, N, Rezaei, S, Rezaeian, M, Rezapour, A, Riad, A, Rikhtegar, R, Rios-Blancas, M, Roberts, T, Rohloff, P, Romero-Rodriguez, E, Roshandel, G, Rwegerera, G, S, M, Saber-Ayad, M, Saberzadeh-Ardestani, B, Sabour, S, Saddik, B, Sadeghi, E, Saeb, M, Saeed, U, Safaei, M, Safary, A, Sahebazzamani, M, Sahebkar, A, Sahoo, H, Sajid, M, Salari, H, Salehi, S, Salem, M, Salimzadeh, H, Samodra, Y, Samy, A, Sanabria, J, Sankararaman, S, Sanmarchi, F, Santric-Milicevic, M, Saqib, M, Sarveazad, A, Sarvi, F, Sathian, B, Satpathy, M, Sayegh, N, Schneider, I, Schwarzinger, M, Sekerija, M, Senthilkumaran, S, Sepanlou, S, Seylani, A, Seyoum, K, Sha, F, Shafaat, O, Shah, P, Shahabi, S, Shahid, I, Shahrbaf, M, Shahsavari, H, Shaikh, M, Shaka, M, Shaker, E, Shannawaz, M, Sharew, M, Sharifi, A, Sharifi-Rad, J, Sharma, P, Shashamo, B, Sheikh, A, Sheikh, M, Sheikhbahaei, S, Sheikhi, R, Sheikhy, A, Shepherd, P, Shetty, A, Shetty, J, Shetty, R, Shibuya, K, Shirkoohi, R, Shirzad-Aski, H, Shivakumar, K, Shivalli, S, Shivarov, V, Shobeiri, P, Shokri Varniab, Z, Shorofi, S, Shrestha, S, Sibhat, M, Siddappa Malleshappa, S, Sidemo, N, Silva, D, Silva, L, Silva Julian, G, Silvestris, N, Simegn, W, Singh, A, Singh, G, Singh, H, Singh, J, Singh, P, Singh, S, Sinha, D, Sinke, A, Siraj, M, Sitas, F, Siwal, S, Skryabin, V, Skryabina, A, Socea, B, Soeberg, M, Sofi-Mahmudi, A, Solomon, Y, Soltani-Zangbar, M, Song, S, Song, Y, Sorensen, R, Soshnikov, S, Sotoudeh, H, Sowe, A, Sufiyan, M, Suk, R, Suleman, M, Suliankatchi Abdulkader, R, Sultana, S, Sur, D, Szocska, M, Tabaeian, S, Tabares-Seisdedos, R, Tabatabaei, S, Tabuchi, T, Tadbiri, H, Taheri, E, Taheri, M, Taheri Soodejani, M, Takahashi, K, Talaat, I, Tampa, M, Tan, K, Tat, N, Tat, V, Tavakoli, A, Tehrani-Banihashemi, A, Tekalegn, Y, Tesfay, F, Thapar, R, Thavamani, A, Thoguluva Chandrasekar, V, Thomas, N, Ticoalu, J, Tiyuri, A, Tollosa, D, Topor-Madry, R, Touvier, M, Tovani-Palone, M, Traini, E, Tran, M, Tripathy, J, Ukke, G, Ullah, I, Ullah, S, Unnikrishnan, B, Vacante, M, Vaezi, M, Valadan Tahbaz, S, Valdez, P, Vardavas, C, Varthya, S, Vaziri, S, Velazquez, D, Veroux, M, Villeneuve, P, Violante, F, Vladimirov, S, Vlassov, V, Vo, B, Vu, L, Wadood, A, Waheed, Y, Walde, M, Wamai, R, Wang, C, Wang, F, Wang, N, Wang, Y, Ward, P, Waris, A, Westerman, R, Wickramasinghe, N, Woldemariam, M, Woldu, B, Xiao, H, Xu, S, Xu, X, Yadav, L, Yahyazadeh Jabbari, S, Yang, L, Yazdanpanah, F, Yeshaw, Y, Yismaw, Y, Yonemoto, N, Younis, M, Yousefi, Z, Yousefian, F, Yu, C, Yu, Y, Yunusa, I, Zahir, M, Zaki, N, Zaman, B, Zangiabadian, M, Zare, F, Zare, I, Zareshahrabadi, Z, Zarrintan, A, Zastrozhin, M, Zeineddine, M, Zhang, D, Zhang, J, Zhang, Y, Zhang, Z, Zhou, L, Zodpey, S, Zoladl, M, Vos, T, Hay, S, Force, L, Murray, C, Epidemiologie, RS: NUTRIM - R3 - Respiratory & Age-related Health, Bill & Melinda Gates Foundation, Kuwait University (Kuwait), Ministry of Higher Education (Malasia), Lega Italiana per la Lotta ai Tumori, Health Effects Institute (Estados Unidos), Unión Europea. Comisión Europea. European Research Council (ERC), Unión Europea. Comisión Europea. H2020, Fundação para a Ciência e Tecnologia (Portugal), African-German Network of Excellence in Science (AGNES), Federal Ministry of Education & Research (Alemania), Alexander von Humboldt Foundation, Novo Nordisk Foundation, National Institute for Health Research (Reino Unido), National Health and Medical Research Council (Australia), Romanian National Authority for Scientific Research and Innovation, Romanian Ministry of Research Innovation and Digitalization, Ministry of Education, Science and Technological Development (Serbia), Sigrid Jusélius Foundation, Finnish Cancer Foundation, Datta Meghe Institute of Medical Sciences (India), Xiamen University (Malasia), Manipal Academy of Higher Education (India), Panjab University (India), Sistema Nacional de Investigación (Panamá), Secretaría Nacional de Ciencia, Tecnología e Innovación (Panamá), Ministry of Science and Technology (Taiwan), Lung Foundation Australia, National Natural Science Foundation of China, Wellcome Trust, UNSW Sydney (Australia), ICMR - National Institute of Epidemiology (India), University of Tasmania (Australia), National Council for Scientific and Technological Development (Brasil), Coordenação de Aperfeicoamento de Pessoal de Nível Superior (Brasil), Institute for Advanced Studies in Basic Sciences (Irán), Ain Shams University (Egipto), International Center of Medical Sciences Research (Islamabad), National Institutes of Health (Estados Unidos), University of Oxford (Reino Unido), National Institute of Genetic Engineering and Biotechnology (Irán), Marga und Walter Boll - Stiftung, Ministero della Salute (Italia), IRCCS Materno Infantile Burlo Garofolo (Italia), King College London, Wellcome Trust/DBT India Alliance (India), Public Health, University of St Andrews. School of Medicine, and University of St Andrews. Population and Behavioural Science Division
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Male ,DEATHS ,DALY, cancer, risk factors ,Medizin ,systematic analysis ,Global Health ,Risk Assessment ,Cancer prevention ,Global Burden of Disease ,RC0254 ,Risk-attributable cancer deaths ,SDG 3 - Good Health and Well-being ,RA0421 ,Risk Factors ,RA0421 Public health. Hygiene. Preventive Medicine ,Quality-Adjusted Life Year ,Neoplasms ,cancer ,Humans ,Global Burden of Disease Study ,UK ,Medicine(all) ,MCC ,RC0254 Neoplasms. Tumors. Oncology (including Cancer) ,Risk Factor ,Smoking ,COVID-19 ,3rd-DAS ,General Medicine ,Disability-adjusted life-years ,SOCIAL DETERMINANTS ,Risk assessments ,risk factor ,Cardiovascular and Metabolic Diseases ,3121 General medicine, internal medicine and other clinical medicine ,OBESITY ,Cancer burden ,Neoplasm ,Female ,LIFE-STYLE ,Quality-Adjusted Life Years ,HEALTH ,RA ,Human ,RC - Abstract
Background: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01-4·94) deaths and 105 million (95·0-116) DALYs for both sexes combined, representing 44·4% (41·3-48·4) of all cancer deaths and 42·0% (39·1-45·6) of all DALYs. There were 2·88 million (2·60-3·18) risk-attributable cancer deaths in males (50·6% [47·8-54·1] of all male cancer deaths) and 1·58 million (1·36-1·84) risk-attributable cancer deaths in females (36·3% [32·5-41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6-28·4) and DALYs by 16·8% (8·8-25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9-42·8] and 33·3% [25·8-42·0]). Interpretation: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. We are grateful to the surveillance systems, including cancer registries, that generated and shared observed cancer burden data. S M Aljunid acknowledges the Department of Health Policy and Management, College of Public Health, Kuwait University for the approval and support to participate in this research project. H Ariffin acknowledges support from the Ministry of Higher Education, Malaysia (grant FRGS/1/2021/SKK0/UM/01/1). F Barra acknowledges support from Lega Italiana per la Lotta contro i Tumori - LILT - Bando 5 x 1000 anno 2019. L Belo and M Carvalho acknowledge the support from FCT in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of UCIBIO and the project LA/P/0140/2020 of i4HB. A J Cohen was supported by the Health Effects Institute, Boston, MA, USA. J Conde acknowledges financial support from the European Research Council - ERC Starting Grant 848325. V M Costa acknowledges her grant (SFRH/BHD/110001/2015), received by Portuguese national funds through Fundação para a Ciência e Tecnologia (FCT), IP, under the Norma Transitória DL57/2016/CP1334/CT0006. T C Ekundayo was supported by the African-German Network of Excellence in Science (AGNES), the Federal Ministry of Education and Research (BMBF) and the Alexander von Humboldt Foundation (AvH). N Ghith acknowledges support from a grant from Novo Nordisk Foundation (NNF16OC0021856). J C Glasbey is support by a Doctoral Research Fellowship from the National Institute of Health Research (NIHR300175). V K Gupta and V B Gupta acknowledge funding support from National Health and Medical Research Council (NHMRC), Australia. C Herteliu, A Pana, and M Ausloos acknowledge partial support by a grant of the Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI, project number PN-III-P4-ID-PCCF-2016-0084. C Herteliu is also partially supported by a grant of the Romanian Ministry of Research Innovation and Digitalization, MCID, project number ID-585-CTR-42-PFE-2021. S Hussain was supported from Operational Programme Research, Development and Education–Project, Postdoc2MUNI (number CZ.02.2. 69/0.0/0.0/18_053/0016952). M Jakovljevic acknowledges partial support through the grant OI 175 014 of the Ministry of Education Science and Technological Development of the Republic of Serbia. J H Kauppila acknowledges research grants from Sigrid Jusélius Foundation and the Finnish Cancer Foundation. M N Khatib acknowledges support from Datta Meghe Institute of Medical Sciences (deemed-to-be-university). Y J Kim was supported by the Research Management Centre, Xiamen University Malaysia [XMUMRF/2020-C6/ITCM/0004]. S L Koulmane Laxminarayana acknowledges institutional assistance by Manipal Academy of Higher Education, Manipal. K Krishan is supported by the UGC Centre of Advanced Study (Phase II), awarded to the Department of Anthropology, Panjab University, Chandigarh, India. I Landires is a member of the Sistema Nacional de Investigación (SNI), which is supported by Panama’s Secretaría Nacional de Ciencia, Tecnología e Innovación (SENACYT). M-C Li was supported by the Ministry of Science and Technology, Taiwan (MOST 110-2314-B-003-001). G Liu acknowledges support from the CREATE Hope scientific fellowship from Lung Foundation Australia. J Liu acknowledges support from the National Natural Science Foundation (72122001). J A Loureiro was supported by Scientific Employment Stimulus (FCT; CEECINST/00049/2018). E Mathews is supported by a Clinical and Public Health Early Career Fellowship (grant number IA/CPHE/17/1/503345) from the DBT India Alliance/Wellcome Trust Department of Biotechnology, India Alliance (2018–2023). T J Meretoja was supported by an unrestricted grant from Cancer Foundation Finland sr. S Mohammed acknowledges a fellowship grant from Alexander von Humboldt Foundation, outside the submitted work. M Molokhia is supported by the National Institute for Health Research Biomedical Research Center at Guy’s and St Thomas’ National Health Service Foundation Trust and King’s College London. L Monasta received support from the Italian Ministry of Health at the Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste - Italy (RC 34/2017). U Mons is supported by the Marga and Walter Boll Foundation, Kerpen, Germany. M A Moosavi acknowledges the financial support of National Institute of Genetics Engineering and Biotechnology (NIGEB). J Musa acknowledges support from the NIH/FICK43TW011416 for research-protected time for cervical cancer research and career development at University of Jos. V Nuñez-Samudio is a member of the Sistema Nacional de Investigación (SNI), which is supported by Panama’s Secretaría Nacional de Ciencia, Tecnología e Innovación (SENACYT). O O Odukoya acknowledges support by the Fogarty International Center of the National Institutes of Health under the award number K43TW010704 for research-protected time. The content is solely the responsibility of all the authors and does not necessarily represent the official views of the National Institutes of Health. A S Oguntade acknowledges funding by a doctoral scholarship from the Nuffield Department of Population Health, University of Oxford (Oxford Population Health). J R Padubidri acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal for their constant support in research collaborations. R G Pestell acknowledges support from NIH grant W81XWH1810605 Breast Cancer Research, Breakthrough Grant R21 CA235139-01. Z Z Piracha acknowledges the International Center of Medical Sciences Research (ICMSR), Islamabad (44000), Pakistan. R A Radhakrishnan acknowledges support from Wellcome Trust/DBT India Alliance - IA/CPHI/18/1/503927. U Saeed acknowledges the International Center of Medical Sciences Research (ICMSR), Islamabad, Pakistan. A M Samy acknowledges the support from Ain Shams University and the Egyptian Fulbright Mission Program. F Sha was supported by the Shenzhen Science and Technology Program (grant number KQTD20190929172835662). H R Shahsavari acknowledges the Institute for Advanced Studies in Basic Sciences (IASBS) Research Council. A Shetty acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal for all the academic support. D A S Silva acknowledges financing in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brazil (CAPES)—Finance Code 001 and D A S Silva is supported in part by CNPq-Brazil (309589/2021-5). L M L R Silva was supported by project CENTRO-04-3559-FSE-000162, Fundo Social Europeu (FSE). Am Singh is supported by the International Graduate Research Scholarship, University of Tasmania. R Suliankatchi Abdulkader acknowledges support from ICMR—National Institute of Epidemiology. B Unnikrishnan acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal. H Xiao acknowledges support from the Public Health Sciences Division of the Fred Hutchinson Cancer Research Center. X Xu is supported by the University of New South Wales (Australia) Scientia Program. C Yu was supported by the National Natural Science Foundation of China (grant number 82173626) and Wuhan Medical Research Program of Joint Fund of Hubei Health Committee (grant number WJ2019H304). Sí
- Published
- 2022
12. The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019
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Elysia M Alvarez, Lisa M Force, Rixing Xu, Kelly Compton, Dan Lu, Hannah Jacqueline Henrikson, Jonathan M Kocarnik, James D Harvey, Alyssa Pennini, Frances E Dean, Weijia Fu, Martina T Vargas, Theresa H M Keegan, Hany Ariffin, Ronald D Barr, Yana Arturovna Erdomaeva, D Sanjeeva Gunasekera, Yetunde O John-Akinola, Tyler G Ketterl, Tezer Kutluk, Marcio Henrique Malogolowkin, Prashant Mathur, Venkatraman Radhakrishnan, Lynn Ann Gloeckler Ries, Carlos Rodriguez-Galindo, Garik Barisovich Sagoyan, Iyad Sultan, Behzad Abbasi, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Michael Abdelmasseh, Sherief Abd-Elsalam, Amir Abdoli, Haimanot Abebe, Aidin Abedi, Hassan Abidi, Hassan Abolhassani, Hiwa Abubaker Ali, Eman Abu-Gharbieh, Basavaprabhu Achappa, Juan Manuel Acuna, Isaac Akinkunmi Adedeji, Oyelola A Adegboye, Qorinah Estiningtyas Sakilah Adnani, Shailesh M Advani, Muhammad Sohail Afzal, Mohamad Aghaie Meybodi, Bahman Ahadinezhad, Bright Opoku Ahinkorah, Sajjad Ahmad, Sepideh Ahmadi, Muktar Beshir Ahmed, Tarik Ahmed Rashid, Yusra Ahmed Salih, Wajeeha Aiman, Gizachew Taddesse Akalu, Hanadi Al Hamad, Fares Alahdab, Abdulhadi A AlAmodi, Fahad Mashhour Alanezi, Turki M Alanzi, Adugnaw Zeleke Alem, Dejene Tsegaye Alem, Yosef Alemayehu, Fadwa Naji Alhalaiqa, Robert Kaba Alhassan, Saqib Ali, Gianfranco Alicandro, Vahid Alipour, Syed Mohamed Aljunid, Motasem Alkhayyat, Sunitha Alluri, Nihad A Almasri, Sadeq Ali Al-Maweri, Sami Almustanyir, Rajaa M Al-Raddadi, Nelson Alvis-Guzman, Edward Kwabena Ameyaw, Saeed Amini, Hubert Amu, Robert Ancuceanu, Catalina Liliana Andrei, Tudorel Andrei, Fereshteh Ansari, Alireza Ansari-Moghaddam, Davood Anvari, Anayochukwu Edward Anyasodor, Jalal Arabloo, Morteza Arab-Zozani, Ayele Mamo Argaw, Muhammad Arshad, Judie Arulappan, Armin Aryannejad, Zatollah Asemi, Mohammad Asghari Jafarabadi, Mohammad Reza Atashzar, Prince Atorkey, Alok Atreya, Sameh Attia, Avinash Aujayeb, Marcel Ausloos, Leticia Avila-Burgos, Atalel Fentahun Awedew, Beatriz Paulina Ayala Quintanilla, Alemu Degu Ayele, Solomon Shitu Ayen, Mohammed A Azab, Sina Azadnajafabad, Hiva Azami, Mohammadreza Azangou-Khyavy, Amirhossein Azari Jafari, Ghasem Azarian, Ahmed Y Azzam, Saeed Bahadory, Jianjun Bai, Atif Amin Baig, Jennifer L Baker, Maciej Banach, Till Winfried Bärnighausen, Francesco Barone-Adesi, Fabio Barra, Amadou Barrow, Huda Basaleem, Abdul-Monim Mohammad Batiha, Masoud Behzadifar, Niguss Cherie Bekele, Rebuma Belete, Uzma Iqbal Belgaumi, Arielle Wilder Bell, Alemshet Yirga Berhie, Devidas S Bhagat, Akshaya Srikanth Bhagavathula, Nikha Bhardwaj, Pankaj Bhardwaj, Sonu Bhaskar, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja, Sadia Bibi, Ali Bijani, Antonio Biondi, Setognal Birara, Tone Bjørge, Obasanjo Afolabi Bolarinwa, Srinivasa Rao Bolla, Archith Boloor, Dejana Braithwaite, Hermann Brenner, Norma B Bulamu, Katrin Burkart, Maria Teresa Bustamante-Teixeira, Nadeem Shafique Butt, Zahid A Butt, Florentino Luciano Caetano dos Santos, Chao Cao, Yin Cao, Giulia Carreras, Ferrán Catalá-López, Francieli Cembranel, Ester Cerin, Raja Chandra Chakinala, Promit Ananyo Chakraborty, Vijay Kumar Chattu, Pankaj Chaturvedi, Akhilanand Chaurasia, Prachi P Chavan, Odgerel Chimed-Ochir, Jee-Young Jasmine Choi, Devasahayam J Christopher, Dinh-Toi Chu, Michael T Chung, Joao Conde, Vera Marisa Costa, Omar B Da'ar, Omid Dadras, Saad M A Dahlawi, Xiaochen Dai, Giovanni Damiani, Emanuele D'Amico, Lalit Dandona, Rakhi Dandona, Parnaz Daneshpajouhnejad, Amira Hamed Darwish, Ahmad Daryani, Fernando Pio De la Hoz, Sisay Abebe Debela, Takele Gezahegn G Demie, Getu Debalkie Demissie, Zeleke Geto Demissie, Edgar Denova-Gutiérrez, Meseret Derbew Molla, Rupak Desai, Abebaw Alemayehu Desta, Deepak Dhamnetiya, Samath Dhamminda Dharmaratne, Mandira Lamichhane Dhimal, Meghnath Dhimal, Mostafa Dianatinasab, Mojtaba Didehdar, Mengistie Diress, Shirin Djalalinia, Huyen Phuc Do, Saeid Doaei, Fariba Dorostkar, Wendel Mombaque dos Santos, Thomas M Drake, Michael Ekholuenetale, Iman El Sayed, Maysaa El Sayed Zaki, Maha El Tantawi, Hassan El-Abid, Mostafa Ahmed Elbahnasawy, Iffat Elbarazi, Hala Rashad Elhabashy, Muhammed Elhadi, Shaimaa I El-Jaafary, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Babak Eshrati, Sharareh Eskandarieh, Mohammed Faisaluddin, Jawad Fares, Umar Farooque, Abidemi Omolara Fasanmi, Wafa Fatima, José Miguel P Ferreira de Oliveira, Simone Ferrero, Lorenzo Ferro Desideri, Getahun Fetensa, Irina Filip, Florian Fischer, James L Fisher, Masoud Foroutan, Takeshi Fukumoto, Peter Andras Gaal, Mohamed M Gad, Piyada Gaewkhiew, Silvano Gallus, Tushar Garg, Teferi Gebru Gebremeskel, Belete Negese Belete Gemeda, Tamiru Getachew, Mansour Ghafourifard, Seyyed-Hadi Ghamari, Ahmad Ghashghaee, Fariba Ghassemi, Nermin Ghith, Ali Gholami, Jamshid Gholizadeh Navashenaq, Syed Amir Gilani, Themba G Ginindza, Abraham Tamirat Gizaw, James C Glasbey, Amit Goel, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Sameer Vali Gopalani, Giuseppe Gorini, Houman Goudarzi, Bárbara Niegia Garcia Goulart, Ayman Grada, Mohammed Ibrahim Mohialdeen Gubari, Maximiliano Ribeiro Guerra, Avirup Guha, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Rasool Haddadi, Nima Hafezi-Nejad, Alemayehu Hailu, Arvin Haj-Mirzaian, Rabih Halwani, Randah R Hamadeh, Mitiku Teshome Hambisa, Sajid Hameed, Samer Hamidi, Shafiul Haque, Sanam Hariri, Josep Maria Haro, Ahmed I Hasaballah, S M Mahmudul Hasan, Seyedeh Melika Hashemi, Treska S Hassan, Soheil Hassanipour, Simon I Hay, Khezar Hayat, Sultan H Hebo, Golnaz Heidari, Mohammad Heidari, Brenda Yuliana Herrera-Serna, Claudiu Herteliu, Demisu Zenbaba Heyi, Kamal Hezam, Michael K Hole, Ramesh Holla, Nobuyuki Horita, Md Mahbub Hossain, Mohammad Bellal Hossain, Mohammad-Salar Hosseini, Mostafa Hosseini, Ali Hosseinzadeh, Mehdi Hosseinzadeh, Mihaela Hostiuc, Sorin Hostiuc, Mowafa Househ, Mohamed Hsairi, Junjie Huang, Nawfal R Hussein, Bing-Fang Hwang, Segun Emmanuel Ibitoye, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Kaire Innos, Lalu Muhammad Irham, Rakibul M Islam, Sheikh Mohammed Shariful Islam, Nahlah Elkudssiah Ismail, Gaetano Isola, Masao Iwagami, Louis Jacob, Farhad Jadidi-Niaragh, Vardhmaan Jain, Mihajlo Jakovljevic, Roksana Janghorban, Amirreza Javadi Mamaghani, Shubha Jayaram, Ranil Jayawardena, Seyed Behzad Jazayeri, Rime Jebai, Ravi Prakash Jha, Tamas Joo, Nitin Joseph, Farahnaz Joukar, Mikk Jürisson, Billingsley Kaambwa, Ali Kabir, Leila R Kalankesh, Feroze Kaliyadan, Zul Kamal, Ashwin Kamath, Himal Kandel, Sitanshu Sekhar Kar, Ibraheem M Karaye, Amirali Karimi, Bekalu Getnet Kassa, Joonas H Kauppila, Phillip M Kemp Bohan, Andre Pascal Kengne, Amene Abebe Kerbo, Mohammad Keykhaei, Yousef Saleh Khader, Himanshu Khajuria, Nastaran Khalili, Neda Khalili, Ejaz Ahmad Khan, Gulfaraz Khan, Maseer Khan, Md Nuruzzaman Khan, Moien AB Khan, Javad Khanali, Maryam Khayamzadeh, Omid Khosravizadeh, Jagdish Khubchandani, Roba Khundkar, Min Seo Kim, Yun Jin Kim, Adnan Kisa, Sezer Kisa, Katarzyna Kissimova-Skarbek, Ali-Asghar Kolahi, Jacek A Kopec, Rajasekaran Koteeswaran, Sindhura Lakshmi Koulmane Laxminarayana, Ai Koyanagi, Nuworza Kugbey, G Anil Kumar, Nithin Kumar, Alexander Kwarteng, Carlo La Vecchia, Qing Lan, Iván Landires, Savita Lasrado, Paolo Lauriola, Caterina Ledda, Sang-woong Lee, Wei-Chen Lee, Yeong Yeh Lee, Yo Han Lee, James Leigh, Elvynna Leong, Bingyu Li, Jiarui Li, Ming-Chieh Li, Stephen S Lim, Xuefeng Liu, Stany W Lobo, Joana A Loureiro, Alessandra Lugo, Raimundas Lunevicius, Hassan Magdy Abd El Razek, Muhammed Magdy Abd El Razek, Morteza Mahmoudi, Azeem Majeed, Alaa Makki, Shilpa Male, Mohammad-Reza Malekpour, Reza Malekzadeh, Ahmad Azam Malik, Mohammed A Mamun, Navid Manafi, Fariborz Mansour-Ghanaei, Borhan Mansouri, Mohammad Ali Mansournia, Santi Martini, Seyedeh Zahra Masoumi, Clara N Matei, Manu Raj Mathur, Colm McAlinden, Ravi Mehrotra, Walter Mendoza, Ritesh G Menezes, Alexios-Fotios A Mentis, Tuomo J Meretoja, Amanual Getnet Mersha, Mohamed Kamal Mesregah, Tomislav Mestrovic, Junmei Miao Jonasson, Bartosz Miazgowski, Irmina Maria Michalek, Ted R Miller, Alemu Basazin Mingude, Seyyedmohammadsadeq Mirmoeeni, Hamed Mirzaei, Sanjeev Misra, Prasanna Mithra, Karzan Abdulmuhsin Mohammad, Mokhtar Mohammadi, Seyyede Momeneh Mohammadi, Abdollah Mohammadian-Hafshejani, Reza Mohammadpourhodki, Arif Mohammed, Shafiu Mohammed, Teroj Abdulrahman Mohammed, Nagabhishek Moka, Ali H Mokdad, Mariam Molokhia, Sara Momtazmanesh, Lorenzo Monasta, Mohammad Ali Moni, Ghobad Moradi, Yousef Moradi, Maliheh Moradzadeh, Rahmatollah Moradzadeh, Paula Moraga, Shane Douglas Morrison, Ebrahim Mostafavi, Amin Mousavi Khaneghah, Christine Mpundu-Kaambwa, Sumaira Mubarik, Lillian Mwanri, Ashraf F Nabhan, Shankar Prasad Nagaraju, Chie Nagata, Mohsen Naghavi, Mukhammad David Naimzada, Luigi Naldi, Vinay Nangia, Atta Abbas Naqvi, Sreenivas Narasimha Swamy, Aparna Ichalangod Narayana, Biswa Prakash Nayak, Vinod C Nayak, Javad Nazari, Sabina Onyinye Nduaguba, Ionut Negoi, Serban Mircea Negru, Seyed Aria Nejadghaderi, Samata Nepal, Sandhya Neupane Kandel, Haruna Asura Nggada, Cuong Tat Nguyen, Chukwudi A Nnaji, Hamed Nosrati, Hasti Nouraei, Ali Nowroozi, Virginia Nuñez-Samudio, Vincent Ebuka Nwatah, Chimezie Igwegbe Nzoputam, Bogdan Oancea, Oluwakemi Ololade Odukoya, Ayodipupo Sikiru Oguntade, In-Hwan Oh, Andrew T Olagunju, Tinuke O Olagunju, Babayemi Oluwaseun Olakunde, Mojisola Morenike Oluwasanu, Emad Omar, Ahmed Omar Bali, Sokking Ong, Obinna E Onwujekwe, Doris V Ortega-Altamirano, Nikita Otstavnov, Stanislav S Otstavnov, Bilcha Oumer, Mayowa O Owolabi, Mahesh P A, Alicia Padron-Monedero, Jagadish Rao Padubidri, Keyvan Pakshir, Adrian Pana, Anamika Pandey, Shahina Pardhan, Fatemeh Pashazadeh Kan, Maja Pasovic, Jenil R Patel, Siddhartha Pati, Sanjay M Pattanshetty, Uttam Paudel, Renato B Pereira, Mario F P Peres, Arokiasamy Perianayagam, Maarten J Postma, Hadi Pourjafar, Akram Pourshams, Akila Prashant, Thejodhar Pulakunta, Mirza Muhammad Fahd Fahd Qadir, Mohammad Rabiee, Navid Rabiee, Amir Radfar, Raghu Anekal Radhakrishnan, Ata Rafiee, Alireza Rafiei, Sima Rafiei, Fakher Rahim, Shadi Rahimzadeh, Mosiur Rahman, Muhammad Aziz Rahman, Amir Masoud Rahmani, Aashish Rajesh, Vajiheh Ramezani-Doroh, Kamal Ranabhat, Priyanga Ranasinghe, Chythra R Rao, Sowmya J Rao, Sina Rashedi, Mahsa Rashidi, Mohammad-Mahdi Rashidi, Goura Kishor Rath, David Laith Rawaf, Salman Rawaf, Lal Rawal, Reza Rawassizadeh, Mohammad Sadegh Razeghinia, Misganu Teshoma Regasa, Andre M N Renzaho, Maryam Rezaei, Negar Rezaei, Nima Rezaei, Mohsen Rezaeian, Aziz Rezapour, Sahba Rezazadeh-Khadem, Abanoub Riad, Ligia Estefania Rios Lopez, Jefferson Antonio Buendia Rodriguez, Luca Ronfani, Gholamreza Roshandel, Godfrey M Rwegerera, Maha Mohamed Saber-Ayad, Siamak Sabour, Basema Saddik, Erfan Sadeghi, Saeid Sadeghian, Umar Saeed, Amirhossein Sahebkar, KM Saif-Ur-Rahman, S Mohammad Sajadi, Sarvenaz Salahi, Sana Salehi, Marwa Rashad Salem, Hamideh Salimzadeh, Abdallah M Samy, Juan Sanabria, Francesco Sanmarchi, Arash Sarveazad, Brijesh Sathian, Monika Sawhney, Susan M Sawyer, Mete Saylan, Ione Jayce Ceola Schneider, Abdul-Aziz Seidu, Mario Šekerija, Endalew Gemechu Sendo, Sadaf G Sepanlou, Allen Seylani, Kenbon Seyoum, Feng Sha, Omid Shafaat, Masood Ali Shaikh, Erfan Shamsoddin, Mohammed Shannawaz, Rajesh Sharma, Sara Sheikhbahaei, Adithi Shetty, B Suresh Kumar Shetty, Pavanchand H Shetty, Jae Il Shin, Reza Shirkoohi, K M Shivakumar, Parnian Shobeiri, Soraya Siabani, Migbar Mekonnen Sibhat, Sudeep K Siddappa Malleshappa, Negussie Boti Sidemo, Diego Augusto Santos Silva, Guilherme Silva Julian, Achintya Dinesh Singh, Jasvinder A Singh, Jitendra Kumar Singh, Surjit Singh, Abiy H Sinke, Yitagesu Sintayehu, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Lee Smith, Ahmad Sofi-Mahmudi, Mohammad Sadegh Soltani-Zangbar, Suhang Song, Emma Elizabeth Spurlock, Paschalis Steiropoulos, Kurt Straif, Ranjeeta Subedi, Mu'awiyyah Babale Sufiyan, Rizwan Suliankatchi Abdulkader, Saima Sultana, Viktória Szerencsés, Miklós Szócska, Seidamir Pasha Tabaeian, Rafael Tabarés-Seisdedos, Mohammadreza Tabary, Takahiro Tabuchi, Hooman Tadbiri, Majid Taheri, Amir Taherkhani, Ken Takahashi, Mircea Tampa, Ker-Kan Tan, Vivian Y Tat, Ahmad Tavakoli, Abdelghani Tbakhi, Arash Tehrani-Banihashemi, Mohamad-Hani Temsah, Fisaha Haile Tesfay, Bekele Tesfaye, Jarnail Singh Thakur, Rekha Thapar, Aravind Thavamani, Arulmani Thiyagarajan, Nihal Thomas, Ruoyan Tobe-Gai, Munkhsaikhan Togtmol, Seyed Abolfazl Tohidast, Hamid Reza Tohidinik, Musliu Adetola Tolani, Daniel Nigusse Tollosa, Mathilde Touvier, Marcos Roberto Tovani-Palone, Eugenio Traini, Bach Xuan Tran, Mai Thi Ngoc Tran, Jaya Prasad Tripathy, Biruk Shalmeno Tusa, Gebresilasea Gendisha Ukke, Irfan Ullah, Saif Ullah, Krishna Kishore Umapathi, Bhaskaran Unnikrishnan, Era Upadhyay, Tolassa Wakayo Ushula, Marco Vacante, Sahel Valadan Tahbaz, Shoban Babu Varthya, Massimiliano Veroux, Paul J Villeneuve, Francesco S Violante, Vasily Vlassov, Giang Thu Vu, Yasir Waheed, Ning Wang, Paul Ward, Adisu Birhanu Weldesenbet, Yi Feng Wen, Ronny Westerman, Andrea Sylvia Winkler, Befikadu Legesse Wubishet, Suowen Xu, Seyed Hossein Yahyazadeh Jabbari, Lin Yang, Sanni Yaya, Vahid Yazdi-Feyzabadi, Taklo Simeneh Yazie, Sisay Shewasinad Yehualashet, Alex Yeshaneh, Yigizie Yeshaw, Birhanu Wubale Yirdaw, Naohiro Yonemoto, Mustafa Z Younis, Zabihollah Yousefi, Chuanhua Yu, Ismaeel Yunusa, Vesna Zadnik, Mazyar Zahir, Telma Zahirian Moghadam, Mohammad Zamani, Maryam Zamanian, Hamed Zandian, Fariba Zare, Mikhail Sergeevich Zastrozhin, Anasthasia Zastrozhina, Jianrong Zhang, Zhi-Jiang Zhang, Arash Ziapour, Mohammad Zoladl, Christopher J L Murray, Christina Fitzmaurice, Archie Bleyer, Nickhill Bhakta, Alvarez E.M., Force L.M., Xu R., Compton K., Lu D., Henrikson H.J., Kocarnik J.M., Harvey J.D., Pennini A., Dean F.E., Fu W., Vargas M.T., Keegan T.H.M., Ariffin H., Barr R.D., Erdomaeva Y.A., Gunasekera D.S., John-Akinola Y.O., Ketterl T.G., Kutluk T., Malogolowkin M.H., Mathur P., Radhakrishnan V., Ries L.A.G., Rodriguez-Galindo C., Sagoyan G.B., Sultan I., Abbasi B., Abbasi-Kangevari M., Abbasi-Kangevari Z., Abbastabar H., Abdelmasseh M., Abd-Elsalam S., Abdoli A., Abebe H., Abedi A., Abidi H., Abolhassani H., Abubaker Ali H., Abu-Gharbieh E., Achappa B., Acuna J.M., Adedeji I.A., Adegboye O.A., Adnani Q.E.S., Advani S.M., Afzal M.S., Aghaie Meybodi M., Ahadinezhad B., Ahinkorah B.O., Ahmad S., Ahmadi S., Ahmed M.B., Ahmed Rashid T., Ahmed Salih Y., Aiman W., Akalu G.T., Al Hamad H., Alahdab F., AlAmodi A.A., Alanezi F.M., Alanzi T.M., Alem A.Z., Alem D.T., Alemayehu Y., Alhalaiqa F.N., Alhassan R.K., Ali S., Alicandro G., Alipour V., Aljunid S.M., Alkhayyat M., Alluri S., Almasri N.A., Al-Maweri S.A., Almustanyir S., Al-Raddadi R.M., Alvis-Guzman N., Ameyaw E.K., Amini S., Amu H., Ancuceanu R., Andrei C.L., Andrei T., Ansari F., Ansari-Moghaddam A., Anvari D., Anyasodor A.E., Arabloo J., Arab-Zozani M., Argaw A.M., Arshad M., Arulappan J., Aryannejad A., Asemi Z., Asghari Jafarabadi M., Atashzar M.R., Atorkey P., Atreya A., Attia S., Aujayeb A., Ausloos M., Avila-Burgos L., Awedew A.F., Ayala Quintanilla B.P., Ayele A.D., Ayen S.S., Azab M.A., Azadnajafabad S., Azami H., Azangou-Khyavy M., Azari Jafari A., Azarian G., Azzam A.Y., Bahadory S., Bai J., Baig A.A., Baker J.L., Banach M., Barnighausen T.W., Barone-Adesi F., Barra F., Barrow A., Basaleem H., Batiha A.-M.M., Behzadifar M., Bekele N.C., Belete R., Belgaumi U.I., Bell A.W., Berhie A.Y., Bhagat D.S., Bhagavathula A.S., Bhardwaj N., Bhardwaj P., Bhaskar S., Bhattacharyya K., Bhojaraja V.S., Bibi S., Bijani A., Biondi A., Birara S., Bjorge T., Bolarinwa O.A., Bolla S.R., Boloor A., Braithwaite D., Brenner H., Bulamu N.B., Burkart K., Bustamante-Teixeira M.T., Butt N.S., Butt Z.A., Caetano dos Santos F.L., Cao C., Cao Y., Carreras G., Catala-Lopez F., Cembranel F., Cerin E., Chakinala R.C., Chakraborty P.A., Chattu V.K., Chaturvedi P., Chaurasia A., Chavan P.P., Chimed-Ochir O., Choi J.-Y.J., Christopher D.J., Chu D.-T., Chung M.T., Conde J., Costa V.M., Da'ar O.B., Dadras O., Dahlawi S.M.A., Dai X., Damiani G., D'Amico E., Dandona L., Dandona R., Daneshpajouhnejad P., Darwish A.H., Daryani A., De la Hoz F.P., Debela S.A., Demie T.G.G., Demissie G.D., Demissie Z.G., Denova-Gutierrez E., Derbew Molla M., Desai R., Desta A.A., Dhamnetiya D., Dharmaratne S.D., Dhimal M.L., Dhimal M., Dianatinasab M., Didehdar M., Diress M., Djalalinia S., Do H.P., Doaei S., Dorostkar F., dos Santos W.M., Drake T.M., Ekholuenetale M., El Sayed I., El Sayed Zaki M., El Tantawi M., El-Abid H., Elbahnasawy M.A., Elbarazi I., Elhabashy H.R., Elhadi M., El-Jaafary S.I., Enyew D.B., Erkhembayar R., Eshrati B., Eskandarieh S., Faisaluddin M., Fares J., Farooque U., Fasanmi A.O., Fatima W., Ferreira de Oliveira J.M.P., Ferrero S., Ferro Desideri L., Fetensa G., Filip I., Fischer F., Fisher J.L., Foroutan M., Fukumoto T., Gaal P.A., Gad M.M., Gaewkhiew P., Gallus S., Garg T., Gebremeskel T.G., Gemeda B.N.B., Getachew T., Ghafourifard M., Ghamari S.-H., Ghashghaee A., Ghassemi F., Ghith N., Gholami A., Gholizadeh Navashenaq J., Gilani S.A., Ginindza T.G., Gizaw A.T., Glasbey J.C., Goel A., Golechha M., Goleij P., Golinelli D., Gopalani S.V., Gorini G., Goudarzi H., Goulart B.N.G., Grada A., Gubari M.I.M., Guerra M.R., Guha A., Gupta B., Gupta S., Gupta V.B., Gupta V.K., Haddadi R., Hafezi-Nejad N., Hailu A., Haj-Mirzaian A., Halwani R., Hamadeh R.R., Hambisa M.T., Hameed S., Hamidi S., Haque S., Hariri S., Haro J.M., Hasaballah A.I., Hasan S.M.M., Hashemi S.M., Hassan T.S., Hassanipour S., Hay S.I., Hayat K., Hebo S.H., Heidari G., Heidari M., Herrera-Serna B.Y., Herteliu C., Heyi D.Z., Hezam K., Hole M.K., Holla R., Horita N., Hossain M.M., Hossain M.B., Hosseini M.-S., Hosseini M., Hosseinzadeh A., Hosseinzadeh M., Hostiuc M., Hostiuc S., Househ M., Hsairi M., Huang J., Hussein N.R., Hwang B.-F., Ibitoye S.E., Ilesanmi O.S., Ilic I.M., Ilic M.D., Innos K., Irham L.M., Islam R.M., Islam S.M.S., Ismail N.E., Isola G., Iwagami M., Jacob L., Jadidi-Niaragh F., Jain V., Jakovljevic M., Janghorban R., Javadi Mamaghani A., Jayaram S., Jayawardena R., Jazayeri S.B., Jebai R., Jha R.P., Joo T., Joseph N., Joukar F., Jurisson M., Kaambwa B., Kabir A., Kalankesh L.R., Kaliyadan F., Kamal Z., Kamath A., Kandel H., Kar S.S., Karaye I.M., Karimi A., Kassa B.G., Kauppila J.H., Kemp Bohan P.M., Kengne A.P., Kerbo A.A., Keykhaei M., Khader Y.S., Khajuria H., Khalili N., Khan E.A., Khan G., Khan M., Khan M.N., Khan M.A., Khanali J., Khayamzadeh M., Khosravizadeh O., Khubchandani J., Khundkar R., Kim M.S., Kim Y.J., Kisa A., Kisa S., Kissimova-Skarbek K., Kolahi A.-A., Kopec J.A., Koteeswaran R., Koulmane Laxminarayana S.L., Koyanagi A., Kugbey N., Kumar G.A., Kumar N., Kwarteng A., La Vecchia C., Lan Q., Landires I., Lasrado S., Lauriola P., Ledda C., Lee S.-W., Lee W.-C., Lee Y.Y., Lee Y.H., Leigh J., Leong E., Li B., Li J., Li M.-C., Lim S.S., Liu X., Lobo S.W., Loureiro J.A., Lugo A., Lunevicius R., Magdy Abd El Razek H., Magdy Abd El Razek M., Mahmoudi M., Majeed A., Makki A., Male S., Malekpour M.-R., Malekzadeh R., Malik A.A., Mamun M.A., Manafi N., Mansour-Ghanaei F., Mansouri B., Mansournia M.A., Martini S., Masoumi S.Z., Matei C.N., Mathur M.R., McAlinden C., Mehrotra R., Mendoza W., Menezes R.G., Mentis A.-F.A., Meretoja T.J., Mersha A.G., Mesregah M.K., Mestrovic T., Miao Jonasson J., Miazgowski B., Michalek I.M., Miller T.R., Mingude A.B., Mirmoeeni S., Mirzaei H., Misra S., Mithra P., Mohammad K.A., Mohammadi M., Mohammadi S.M., Mohammadian-Hafshejani A., Mohammadpourhodki R., Mohammed A., Mohammed S., Mohammed T.A., Moka N., Mokdad A.H., Molokhia M., Momtazmanesh S., Monasta L., Moni M.A., Moradi G., Moradi Y., Moradzadeh M., Moradzadeh R., Moraga P., Morrison S.D., Mostafavi E., Mousavi Khaneghah A., Mpundu-Kaambwa C., Mubarik S., Mwanri L., Nabhan A.F., Nagaraju S.P., Nagata C., Naghavi M., Naimzada M.D., Naldi L., Nangia V., Naqvi A.A., Narasimha Swamy S., Narayana A.I., Nayak B.P., Nayak V.C., Nazari J., Nduaguba S.O., Negoi I., Negru S.M., Nejadghaderi S.A., Nepal S., Neupane Kandel S., Nggada H.A., Nguyen C.T., Nnaji C.A., Nosrati H., Nouraei H., Nowroozi A., Nunez-Samudio V., Nwatah V.E., Nzoputam C.I., Oancea B., Odukoya O.O., Oguntade A.S., Oh I.-H., Olagunju A.T., Olagunju T.O., Olakunde B.O., Oluwasanu M.M., Omar E., Omar Bali A., Ong S., Onwujekwe O.E., Ortega-Altamirano D.V., Otstavnov N., Otstavnov S.S., Oumer B., Owolabi M.O., P A M., Padron-Monedero A., Padubidri J.R., Pakshir K., Pana A., Pandey A., Pardhan S., Pashazadeh Kan F., Pasovic M., Patel J.R., Pati S., Pattanshetty S.M., Paudel U., Pereira R.B., Peres M.F.P., Perianayagam A., Postma M.J., Pourjafar H., Pourshams A., Prashant A., Pulakunta T., Qadir M.M.F.F., Rabiee M., Rabiee N., Radfar A., Radhakrishnan R.A., Rafiee A., Rafiei A., Rafiei S., Rahim F., Rahimzadeh S., Rahman M., Rahman M.A., Rahmani A.M., Rajesh A., Ramezani-Doroh V., Ranabhat K., Ranasinghe P., Rao C.R., Rao S.J., Rashedi S., Rashidi M., Rashidi M.-M., Rath G.K., Rawaf D.L., Rawaf S., Rawal L., Rawassizadeh R., Razeghinia M.S., Regasa M.T., Renzaho A.M.N., Rezaei M., Rezaei N., Rezaeian M., Rezapour A., Rezazadeh-Khadem S., Riad A., Rios Lopez L.E., Rodriguez J.A.B., Ronfani L., Roshandel G., Rwegerera G.M., Saber-Ayad M.M., Sabour S., Saddik B., Sadeghi E., Sadeghian S., Saeed U., Sahebkar A., Saif-Ur-Rahman K.M., Sajadi S.M., Salahi S., Salehi S., Salem M.R., Salimzadeh H., Samy A.M., Sanabria J., Sanmarchi F., Sarveazad A., Sathian B., Sawhney M., Sawyer S.M., Saylan M., Schneider I.J.C., Seidu A.-A., Sekerija M., Sendo E.G., Sepanlou S.G., Seylani A., Seyoum K., Sha F., Shafaat O., Shaikh M.A., Shamsoddin E., Shannawaz M., Sharma R., Sheikhbahaei S., Shetty A., Shetty B.S.K., Shetty P.H., Shin J.I., Shirkoohi R., Shivakumar K.M., Shobeiri P., Siabani S., Sibhat M.M., Siddappa Malleshappa S.K., Sidemo N.B., Silva D.A.S., Silva Julian G., Singh A.D., Singh J.A., Singh J.K., Singh S., Sinke A.H., Sintayehu Y., Skryabin V.Y., Skryabina A.A., Smith L., Sofi-Mahmudi A., Soltani-Zangbar M.S., Song S., Spurlock E.E., Steiropoulos P., Straif K., Subedi R., Sufiyan M.B., Suliankatchi Abdulkader R., Sultana S., Szerencses V., Szocska M., Tabaeian S.P., Tabares-Seisdedos R., Tabary M., Tabuchi T., Tadbiri H., Taheri M., Taherkhani A., Takahashi K., Tampa M., Tan K.-K., Tat V.Y., Tavakoli A., Tbakhi A., Tehrani-Banihashemi A., Temsah M.-H., Tesfay F.H., Tesfaye B., Thakur J.S., Thapar R., Thavamani A., Thiyagarajan A., Thomas N., Tobe-Gai R., Togtmol M., Tohidast S.A., Tohidinik H.R., Tolani M.A., Tollosa D.N., Touvier M., Tovani-Palone M.R., Traini E., Tran B.X., Tran M.T.N., Tripathy J.P., Tusa B.S., Ukke G.G., Ullah I., Ullah S., Umapathi K.K., Unnikrishnan B., Upadhyay E., Ushula T.W., Vacante M., Valadan Tahbaz S., Varthya S.B., Veroux M., Villeneuve P.J., Violante F.S., Vlassov V., Vu G.T., Waheed Y., Wang N., Ward P., Weldesenbet A.B., Wen Y.F., Westerman R., Winkler A.S., Wubishet B.L., Xu S., Yahyazadeh Jabbari S.H., Yang L., Yaya S., Yazdi-Feyzabadi V., Yazie T.S., Yehualashet S.S., Yeshaneh A., Yeshaw Y., Yirdaw B.W., Yonemoto N., Younis M.Z., Yousefi Z., Yu C., Yunusa I., Zadnik V., Zahir M., Zahirian Moghadam T., Zamani M., Zamanian M., Zandian H., Zare F., Zastrozhin M.S., Zastrozhina A., Zhang J., Zhang Z.-J., Ziapour A., Zoladl M., Murray C.J.L., Fitzmaurice C., Bleyer A., Bhakta N., Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE), Microbes in Health and Disease (MHD), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), HUS Comprehensive Cancer Center, University of Helsinki, Bill & Melinda Gates Foundation, American Lebanese Syrian Associated Charities, St. Baldrick's Foundation, NIH - National Cancer Institute (NCI) (Estados Unidos), Epidemiologie, and RS: NUTRIM - R3 - Respiratory & Age-related Health
- Subjects
adolescent cancer, global burden of disease, epidemiology ,Adult ,Male ,Adolescent ,3122 Cancers ,UNITED-STATES ,Disability-Adjusted Life Year ,Adolescents ,Socioeconomic Factor ,Global Health ,Global Burden of Disease ,Young Adult ,Life Expectancy ,SDG 3 - Good Health and Well-being ,Risk Factors ,WORLDWIDE ,Neoplasms ,Cause of Death ,Prevalence ,Humans ,1112 Oncology and Carcinogenesis ,Oncology & Carcinogenesis ,Mortality ,Cancer burden analyses ,Cancer ,ACUTE LYMPHOBLASTIC-LEUKEMIA ,disease ,Global burden ,OUTCOMES ,CHILDHOOD-CANCER ,Incidence ,Risk Factor ,the GBD 2019 methodology ,Disability-Adjusted Life Years ,GBD 2019 Adolescent Young Adult Cancer Collaborators ,CARE ,Cancer control efforts ,Socioeconomic Factors ,Oncology ,Neoplasm ,Female ,Young adults ,Human - Abstract
Funding: J A Loureiro acknowledges support from Base Funding UIDB/00511/2020 of the LEPABE funded by national funds through the FCT/MCTES (PIDDAC) and Scientific Employment Stimulus (FCT) [CEECINST/00049/2018]. Background: In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15–39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults. Methods: Using the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15–39 years to define adolescents and young adults. Findings: There were 1·19 million (95% UI 1·11–1·28) incident cancer cases and 396 000 (370 000–425 000) deaths due to cancer among people aged 15–39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59·6 [54·5–65·7] per 100 000 person-years) and high-middle SDI countries (53·2 [48·8–57·9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14·2 [12·9–15·6] per 100 000 person-years) and middle SDI (13·6 [12·6–14·8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23·5 million (21·9–25·2) DALYs to the global burden of disease, of which 2·7% (1·9–3·6) came from YLDs and 97·3% (96·4–98·1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally. Interpretation: Adolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts. Funding: Bill & Melinda Gates Foundation, American Lebanese Syrian Associated Charities, St Baldrick's Foundation, and the National Cancer Institute. publishersversion published
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- 2022
13. Assessing performance of the Healthcare Access and Quality Index, overall and by select age groups, for 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019
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Lozano, R., Haakenstad, A., Yearwood, J. A., Fullman, N., Bintz, C., Bienhoff, K., Weaver, M. R., Nandakumar, V., Joffe, J. N., LeGrand, K. E., Knight, M., Abbafati, C., Abbasi-Kangevari, M., Abdoli, A., Zuniga, R. A. A., Adedeji, I. A., Adekanmbi, V., Adetokunboh, O. O., Afzal, M. S., Afzal, S., Agudelo-Botero, M., Ahinkorah, B. O., Ahmad, S., Ahmadi, A., Ahmadi, S., Ahmed, A., Rashid, T. A., Aji, B., Akande-Sholabi, W., Alam, K., Al Hamad, H., Alhassan, R. K., Ali, L., Alipour, V., Aljunid, S. M., Ameyaw, E. K., Amin, T. T., Amu, H., Amugsi, D. A., Ancuceanu, R., Andrade, P. P., Anjum, A., Arabloo, J., Arab-Zozani, M., Ariffin, H., Arulappan, J., Aryan, Z., Ashraf, T., Atnafu, D. D., Atreya, A., Ausloos, M., Avila-Burgos, L., Ayano, G., Ayanore, M. A., Azari, S., Badiye, A. D., Baig, A. A., Bairwa, M., Bakkannavar, S. M., Baliga, S., Banik, P. C., Barnighausen, T. W., Barra, F., Barrow, A., Basu, S., Bayati, M., Belete, R., Bell, A. W., Bhagat, D. S., Bhagavathula, A. S., Bhardwaj, P., Bhardwaj, N., Bhaskar, S., Bhattacharyya, K., Bhutta, Z. A., Bibi, S., Bijani, A., Bikbov, B., Biondi, A., Bolarinwa, O. A., Bonny, A., Brenner, H., Buonsenso, D., Burkart, K., Busse, R., Butt, Z. A., Butt, N. S., dos Santos, F. L. C., Cahuana Hurtado, Lucero, Camera, Luis Alberto, Cardenas, R., Carneiro, V. L. A., Catala-Lopez, F., Chandan, J. S., Charan, J., Chavan, P. P., Chen, S. M., Chen, S., Choudhari, S. G., Chowdhury, E. K., Chowdhury, M. A. K., Cirillo, M., Corso, B., Dadras, O., Dahlawi, S. M. A., Dai, X. C., Dandona, L., Dandona, R., Dangel, W. J., Davila-Cervantes, C. A., Davletov, K., Deuba, K., Dhimal, M., Dhimal, M. L., Djalalinia, S., Do, H. P., Doshmangir, L., Duncan, B. B., Effiong, A., Ehsani-Chimeh, E., Elgendy, I. Y., Elhadi, M., El Sayed, I., El Tantawi, M., Erku, D. A., Eskandarieh, S., Fares, J., Farzadfar, F., Ferrero, S., Desideri, L. F., Fischer, F., Foigt, N. A., Foroutan, M., Fukumoto, T., Gaal, P. A., Gaihre, S., Gardner, W. M., Garg, T., Obsa, A. G., Ghafourifard, M., Ghashghaee, A., Ghith, N., Gilani, S. A., Gill, P. S., Goharinezhad, S., Golechha, M., Guadamuz, J. S., Guo, Y. M., Das Gupta, R., Gupta, R., Gupta, V. K., Gupta, V. B., Hamiduzzaman, M., Hanif, A., Haro, J. M., Hasaballah, A. I., Hasan, M. M., Hasan, M. T., Hashi, A., Hay, S. I., Hayat, K., Heidari, M., Heidari, G., Henry, N. J., Herteliu, C., Holla, R., Hossain, S., Hossain, S. J., Hossain, M. B. H., Hosseinzadeh, M., Hostiuc, S., Hoveidamanesh, S., Hsieh, V. C. R., Hu, G. Q., Huang, J. J., Huda, M. M., Ifeagwu, S. C., Ikuta, K. S., Ilesanmi, O. S., Irvani, S. S. N., Islam, R. M., Islam, S. M. S., Ismail, N. E., Iso, H., Isola, G., Itumalla, R., Iwagami, M., Jahani, M. A., Jahanmehr, N., Jain, R., Jakovljevic, M., Janodia, M. D., Jayapal, S. K., Jayaram, S., Jha, R. P., Jonas, J. B., Joo, T., Joseph, N., Jurisson, M., Kabir, A., Kalankesh, L. R., Kalhor, R., Kamath, A. M., Kamenov, K., Kandel, H., Kantar, R. S., Kapoor, N., Karanikolos, M., Katikireddi, S. V., Kavetskyy, T., Kawakami, N., Kayode, G. A., Keikavoosi-Arani, L., Keykhaei, M., Khader, Y. S., Khajuria, H., Khalilov, R., Khammarnia, M., Khan, M. N., Khan, M. A. B., Khan, M., Khezeli, M., Kim, M. S., Kim, Y. J., Kisa, S., Kisa, A., Klymchuk, V., Koly, K. N., Korzh, O., Kosen, S., Koul, P. A., Defo, B. K., Kumar, G. A., Kusuma, D., Kyu, H. H., Larsson, A. O., Lasrado, S., Lee, W. C., Lee, Y. H., Lee, C. B., Li, S. S., Lucchetti, G., Mahajan, P. B., Majeed, A., Makki, A., Malekzadeh, R., Malik, A. A., Malta, D. C., Mansournia, M. A., Mantovani, L. G., Martinez-Valle, A., Martins-Melo, F. R., Masoumi, S. Z., Mathur, M. R., Maude, R. J., Maulik, P. K., McKee, M., Mendoza, W., Menezes, R. G., Mensah, G. A., Meretoja, A., Meretoja, T. J., Mestrovic, T., Michalek, I. M., Mirrakhimov, E. M., Misganaw, A., Misra, S., Moazen, B., Mohammadi, M., Mohammed, S., Moitra, M., Mokdad, A. H., Molokhia, M., Monasta, L., Moni, M. A., Moradi, G., Moreira, R. S., Mosser, J. F., Mostafavi, E., Mouodi, S., Nagarajan, A. J., Nagata, C., Naghavi, M., Nangia, V., Swamy, S. N., Narayana, A. I., Nascimento, B. R., Nassereldine, H., Nayak, B. P., Nazari, J., Negoi, I., Nepal, S., Kandel, S. N., Ngunjiri, J. W., Nguyen, H. L. T, Nguyen, C. T., Ningrum, D. N. A., Noubiap, J. J., Oancea, B., Oghenetega, O. B., Oh, I. H., Olagunju, A. T., Olakunde, B. O., Bali, A. O., Omer, E., Onwujekwe, O. E., Otoiu, A., Padubidri, J. R., Palladino, R., Pana, A., Panda-Jonas, S., Pandi-Perumal, S. R., Pardhan, S., Pasupula, D. K., Pathak, P. K., Patton, G. C., Pawar, S., Pereira, J., Pilania, M., Piroozi, B., Podder, V., Pokhrel, K. N., Postma, M. J., Prada, S. I., Syed, Z. Q., Rabiee, N., Radhakrishnan, R. A., Rahman, M. M., Rahman, M., Rahman, M. H. U., Rahmani, A. M., Ranabhat, C. L., Rao, C. R., Rao, S. J., Rasella, D., Rawaf, S., Rawaf, D. L., Rawal, L., Renzaho, A. M. N., Reshmi, B., Resnikoff, S., Rezapour, A., Riahi, S. M., Ripon, R. K., Sacco, S., Sadeghi, M., Saeed, U., Sahebkar, A., Sahiledengle, B., Sahoo, H., Sahu, M., Salama, J. S., Salamati, P., Samy, A. M., Sanabria, J., Santric-Milicevic, M. M., Sathian, B., Sawhney, M., Schmidt, M. I., Seidu, A. A., Sepanlou, S. G., Seylani, A., Shaikh, M. A., Sheikh, A., Shetty, A., Shigematsu, M., Shiri, R., Shivakumar, K. M., Shokri, A., Singh, J. A., Sinha, D. N., Skryabin, V. Y., Skryabina, A. A., Sofi-Mahmudi, A., Sousa, R. A. R. C., Stephens, J. H., Sun, J., Szocska, M., Tabares-Seisdedos, R., Tadbiri, H., Tamiru, A. T., Thankappan, K. R., Topor-Madry, R., Tovani-Palone, M. R., Tran, M. T. N., Tran, B. X., Tripathi, N., Tripathy, J. P., Troeger, C. E., Uezono, D. R., Ullah, S., Ullah, A., Unnikrishnan, B., Vacante, M., Tahbaz, S. V., Valdez, P. R., Vasic, M., Veroux, M., Vervoort, D., Violante, F. S., Vladimirov, S. K., Vlassov, V., Vo, B., Waheed, Y., Wamai, R. G., Wang, Y. P., Wang, Y. Z., Ward, P., Wiangkham, T., Yadav, L., Jabbari, S. H. Y., Yamagishi, K., Yaya, S., Yazdi-Feyzabadi, V., Yi, S. Y., Yigit, V., Yonemoto, N., Younis, M. Z., Yu, C. H., Yunusa, I., Bin Zaman, S., Zastrozhin, M. S., Zhang, Z. J., Zhong, C. W., Zuniga, Y. M. H., Lim, S. S., Murray, C. J. L., GBD 2019 Healthcare Access Quality, Clinicum, Department of Neurosciences, HUS Comprehensive Cancer Center, Haakenstad, Annie, Yearwood, Jamal Akeem, Fullman, Nancy, Bintz, Corinne, Bienhoff, Kelly, Weaver, Marcia R, Nandakumar, Vishnu, Joffe, Jonah N, Legrand, Kate E, Knight, Megan, Abbafati, Cristiana, Abbasi-Kangevari, Mohsen, Abdoli, Amir, Abeldaño Zuñiga, Roberto Ariel, Adedeji, Isaac Akinkunmi, Adekanmbi, Victor, Adetokunboh, Olatunji O, Afzal, Muhammad Sohail, Afzal, Saira, Agudelo-Botero, Marcela, Ahinkorah, Bright Opoku, Ahmad, Sajjad, Ahmadi, Ali, Ahmadi, Sepideh, Ahmed, Ali, Ahmed Rashid, Tarik, Aji, Budi, Akande-Sholabi, Wuraola, Alam, Khurshid, Al Hamad, Hanadi, Alhassan, Robert Kaba, Ali, Liaqat, Alipour, Vahid, Aljunid, Syed Mohamed, Ameyaw, Edward Kwabena, Amin, Tarek Tawfik, Amu, Hubert, Amugsi, Dickson A, Ancuceanu, Robert, Andrade, Pedro Prata, Anjum, Afifa, Arabloo, Jalal, Arab-Zozani, Morteza, Ariffin, Hany, Arulappan, Judie, Aryan, Zahra, Ashraf, Tahira, Atnafu, Desta Debalkie, Atreya, Alok, Ausloos, Marcel, Avila-Burgos, Leticia, Ayano, Getinet, Ayanore, Martin Amogre, Azari, Samad, Badiye, Ashish D, Baig, Atif Amin, Bairwa, Mohan, Bakkannavar, Shankar M, Baliga, Shrikala, Banik, Palash Chandra, Bärnighausen, Till Winfried, Barra, Fabio, Barrow, Amadou, Basu, Sanjay, Bayati, Mohsen, Belete, Rebuma, Bell, Arielle Wilder, Bhagat, Devidas S, Bhagavathula, Akshaya Srikanth, Bhardwaj, Pankaj, Bhardwaj, Nikha, Bhaskar, Sonu, Bhattacharyya, Krittika, Bhutta, Zulfiqar A, Bibi, Sadia, Bijani, Ali, Bikbov, Bori, Biondi, Antonio, Bolarinwa, Obasanjo Afolabi, Bonny, Aime, Brenner, Hermann, Buonsenso, Danilo, Burkart, Katrin, Busse, Reinhard, Butt, Zahid A, Butt, Nadeem Shafique, Caetano dos Santos, Florentino Luciano, Cahuana-Hurtado, Lucero, Cámera, Luis Alberto, Cárdenas, Rosario, Carneiro, Vera L A, Catalá-López, Ferrán, Chandan, Joht Singh, Charan, Jaykaran, Chavan, Prachi P, Chen, Simiao, Chen, Shu, Choudhari, Sonali Gajanan, Chowdhury, Enayet Karim, Chowdhury, Mohiuddin Ahsanul Kabir, Cirillo, Massimo, Corso, Barbara, Dadras, Omid, Dahlawi, Saad M A, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, Dangel, William Jame, Dávila-Cervantes, Claudio Alberto, Davletov, Kairat, Deuba, Keshab, Dhimal, Meghnath, Dhimal, Mandira Lamichhane, Djalalinia, Shirin, Do, Huyen Phuc, Doshmangir, Leila, Duncan, Bruce B, Effiong, Andem, Ehsani-Chimeh, Elham, Elgendy, Islam Y, Elhadi, Muhammed, El Sayed, Iman, El Tantawi, Maha, Erku, Daniel Asfaw, Eskandarieh, Sharareh, Fares, Jawad, Farzadfar, Farshad, Ferrero, Simone, Ferro Desideri, Lorenzo, Fischer, Florian, Foigt, Nataliya A, Foroutan, Masoud, Fukumoto, Takeshi, Gaal, Peter Andra, Gaihre, Santosh, Gardner, William M, Garg, Tushar, Getachew Obsa, Abera, Ghafourifard, Mansour, Ghashghaee, Ahmad, Ghith, Nermin, Gilani, Syed Amir, Gill, Paramjit Singh, Goharinezhad, Salime, Golechha, Mahaveer, Guadamuz, Jenny S, Guo, Yuming, Gupta, Rajat Da, Gupta, Rajeev, Gupta, Vivek Kumar, Gupta, Veer Bala, Hamiduzzaman, Mohammad, Hanif, Asif, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, Md Mehedi, Hasan, M Tasdik, Hashi, Abdiwahab, Hay, Simon I, Hayat, Khezar, Heidari, Mohammad, Heidari, Golnaz, Henry, Nathaniel J, Herteliu, Claudiu, Holla, Ramesh, Hossain, Sahadat, Hossain, Sheikh Jamal, Hossain, Mohammad Bellal Hossain, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Hoveidamanesh, Soodabeh, Hsieh, Vivian Chia-rong, Hu, Guoqing, Huang, Junjie, Huda, M Mamun, Ifeagwu, Susan C, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Islam, Rakibul M, Islam, Sheikh Mohammed Shariful, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Itumalla, Ramaiah, Iwagami, Masao, Jahani, Mohammad Ali, Jahanmehr, Nader, Jain, Rajesh, Jakovljevic, Mihajlo, Janodia, Manthan Dilipkumar, Jayapal, Sathish Kumar, Jayaram, Shubha, Jha, Ravi Prakash, Jonas, Jost B, Joo, Tama, Joseph, Nitin, Jürisson, Mikk, Kabir, Ali, Kalankesh, Leila R, Kalhor, Rohollah, Kamath, Aruna M, Kamenov, Kaloyan, Kandel, Himal, Kantar, Rami S, Kapoor, Neeti, Karanikolos, Marina, Katikireddi, Srinivasa Vittal, Kavetskyy, Tara, Kawakami, Norito, Kayode, Gbenga A, Keikavoosi-Arani, Leila, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khalilov, Rovshan, Khammarnia, Mohammad, Khan, Md Nuruzzaman, Khan, Moien AB, Khan, Maseer, Khezeli, Mehdi, Kim, Min Seo, Kim, Yun Jin, Kisa, Sezer, Kisa, Adnan, Klymchuk, Vitalii, Koly, Kamrun Nahar, Korzh, Oleksii, Kosen, Soewarta, Koul, Parvaiz A, Kuate Defo, Barthelemy, Kumar, G Anil, Kusuma, Dian, Kyu, Hmwe Hmwe, Larsson, Anders O, Lasrado, Savita, Lee, Wei-Chen, Lee, Yo Han, Lee, Chiachi Bonnie, Li, Shanshan, Lucchetti, Giancarlo, Mahajan, Preetam Bhalchandra, Majeed, Azeem, Makki, Alaa, Malekzadeh, Reza, Malik, Ahmad Azam, Malta, Deborah Carvalho, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Martinez-Valle, Adolfo, Martins-Melo, Francisco Rogerlândio, Masoumi, Seyedeh Zahra, Mathur, Manu Raj, Maude, Richard Jame, Maulik, Pallab K, Mckee, Martin, Mendoza, Walter, Menezes, Ritesh G, Mensah, George A, Meretoja, Atte, Meretoja, Tuomo J, Mestrovic, Tomislav, Michalek, Irmina Maria, Mirrakhimov, Erkin M, Misganaw, Awoke, Misra, Sanjeev, Moazen, Babak, Mohammadi, Mokhtar, Mohammed, Shafiu, Moitra, Modhurima, Mokdad, Ali H, Molokhia, Mariam, Monasta, Lorenzo, Moni, Mohammad Ali, Moradi, Ghobad, Moreira, Rafael Silveira, Mosser, Jonathan F, Mostafavi, Ebrahim, Mouodi, Simin, Nagarajan, Ahamarshan Jayaraman, Nagata, Chie, Naghavi, Mohsen, Nangia, Vinay, Narasimha Swamy, Sreeniva, Narayana, Aparna Ichalangod, Nascimento, Bruno Ramo, Nassereldine, Hasan, Nayak, Biswa Prakash, Nazari, Javad, Negoi, Ionut, Nepal, Samata, Neupane Kandel, Sandhya, Ngunjiri, Josephine W, Nguyen, Huong Lan Thi, Nguyen, Cuong Tat, Ningrum, Dina Nur Anggraini, Noubiap, Jean Jacque, Oancea, Bogdan, Oghenetega, Onome Bright, Oh, In-Hwan, Olagunju, Andrew T, Olakunde, Babayemi Oluwaseun, Omar Bali, Ahmed, Omer, Emad, Onwujekwe, Obinna E, Otoiu, Adrian, Padubidri, Jagadish Rao, Palladino, Raffaele, Pana, Adrian, Panda-Jonas, Songhomitra, Pandi-Perumal, Seithikurippu R, Pardhan, Shahina, Pasupula, Deepak Kumar, Pathak, Praveen Kumar, Patton, George C, Pawar, Shrikant, Pereira, Jeevan, Pilania, Manju, Piroozi, Bakhtiar, Podder, Vivek, Pokhrel, Khem Narayan, Postma, Maarten J, Prada, Sergio I, Quazi Syed, Zahiruddin, Rabiee, Navid, Radhakrishnan, Raghu Anekal, Rahman, Md Mosfequr, Rahman, Mosiur, Rahman, Mahfuzar, Rahman, Mohammad Hifz Ur, Rahmani, Amir Masoud, Ranabhat, Chhabi Lal, Rao, Chythra R, Rao, Sowmya J, Rasella, Davide, Rawaf, Salman, Rawaf, David Laith, Rawal, Lal, Renzaho, Andre M N, Reshmi, Bhageerathy, Resnikoff, Serge, Rezapour, Aziz, Riahi, Seyed Mohammad, Ripon, Rezaul Karim, Sacco, Simona, Sadeghi, Masoumeh, Saeed, Umar, Sahebkar, Amirhossein, Sahiledengle, Biniyam, Sahoo, Harihar, Sahu, Maitreyi, Salama, Joseph S, Salamati, Payman, Samy, Abdallah M, Sanabria, Juan, Santric-Milicevic, Milena M, Sathian, Brijesh, Sawhney, Monika, Schmidt, Maria Inê, Seidu, Abdul-Aziz, Sepanlou, Sadaf G, Seylani, Allen, Shaikh, Masood Ali, Sheikh, Aziz, Shetty, Adithi, Shigematsu, Mika, Shiri, Rahman, Shivakumar, K M, Shokri, Azad, Singh, Jasvinder A, Sinha, Dhirendra Narain, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Sofi-Mahmudi, Ahmad, Sousa, Raúl A R C, Stephens, Jacqueline H, Sun, Jing, Szócska, Mikló, Tabarés-Seisdedos, Rafael, Tadbiri, Hooman, Tamiru, Animut Tagele, Thankappan, Kavumpurathu Raman, Topor-Madry, Roman, Tovani-Palone, Marcos Roberto, Tran, Mai Thi Ngoc, Tran, Bach Xuan, Tripathi, Niharika, Tripathy, Jaya Prasad, Troeger, Christopher E, Uezono, Deinzel Roble, Ullah, Saif, Ullah, Anayat, Unnikrishnan, Bhaskaran, Vacante, Marco, Valadan Tahbaz, Sahel, Valdez, Pascual R, Vasic, Milena, Veroux, Massimiliano, Vervoort, Dominique, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vo, Bay, Waheed, Yasir, Wamai, Richard G, Wang, Yuan-Pang, Wang, Yanzhong, Ward, Paul, Wiangkham, Taweewat, Yadav, Lalit, Yahyazadeh Jabbari, Seyed Hossein, Yamagishi, Kazumasa, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yi, Siyan, Yiğit, Vahit, Yonemoto, Naohiro, Younis, Mustafa Z, Yu, Chuanhua, Yunusa, Ismaeel, Zaman, Sojib Bin, Zastrozhin, Mikhail Sergeevich, Zhang, Zhi-Jiang, Zhong, Chenwen, Zuniga, Yves Miel H, Lim, Stephen S, Murray, Christopher J L, Lozano, Rafael, Haakenstad, A, Yearwood, J, Fullman, N, Bintz, C, Bienhoff, K, Weaver, M, Nandakumar, V, Joffe, J, Legrand, K, Knight, M, Abbafati, C, Abbasi-Kangevari, M, Abdoli, A, Abeldano Zuniga, R, Adedeji, I, Adekanmbi, V, Adetokunboh, O, Afzal, M, Afzal, S, Agudelo-Botero, M, Ahinkorah, B, Ahmad, S, Ahmadi, A, Ahmadi, S, Ahmed, A, Ahmed Rashid, T, Aji, B, Akande-Sholabi, W, Alam, K, Al Hamad, H, Alhassan, R, Ali, L, Alipour, V, Aljunid, S, Ameyaw, E, Amin, T, Amu, H, Amugsi, D, Ancuceanu, R, Andrade, P, Anjum, A, Arabloo, J, Arab-Zozani, M, Ariffin, H, Arulappan, J, Aryan, Z, Ashraf, T, Atnafu, D, Atreya, A, Ausloos, M, Avila-Burgos, L, Ayano, G, Ayanore, M, Azari, S, Badiye, A, Baig, A, Bairwa, M, Bakkannavar, S, Baliga, S, Banik, P, Barnighausen, T, Barra, F, Barrow, A, Basu, S, Bayati, M, Belete, R, Bell, A, Bhagat, D, Bhagavathula, A, Bhardwaj, P, Bhardwaj, N, Bhaskar, S, Bhattacharyya, K, Bhutta, Z, Bibi, S, Bijani, A, Bikbov, B, Biondi, A, Bolarinwa, O, Bonny, A, Brenner, H, Buonsenso, D, Burkart, K, Busse, R, Butt, Z, Butt, N, Caetano dos Santos, F, Cahuana-Hurtado, L, Camera, L, Cardenas, R, Carneiro, V, Catala-Lopez, F, Chandan, J, Charan, J, Chavan, P, Chen, S, Choudhari, S, Chowdhury, E, Chowdhury, M, Cirillo, M, Corso, B, Dadras, O, Dahlawi, S, Dai, X, Dandona, L, Dandona, R, Dangel, W, Davila-Cervantes, C, Davletov, K, Deuba, K, Dhimal, M, Djalalinia, S, Do, H, Doshmangir, L, Duncan, B, Effiong, A, Ehsani-Chimeh, E, Elgendy, I, Elhadi, M, El Sayed, I, El Tantawi, M, Erku, D, Eskandarieh, S, Fares, J, Farzadfar, F, Ferrero, S, Ferro Desideri, L, Fischer, F, Foigt, N, Foroutan, M, Fukumoto, T, Gaal, P, Gaihre, S, Gardner, W, Garg, T, Getachew Obsa, A, Ghafourifard, M, Ghashghaee, A, Ghith, N, Gilani, S, Gill, P, Goharinezhad, S, Golechha, M, Guadamuz, J, Guo, Y, Gupta, R, Gupta, V, Hamiduzzaman, M, Hanif, A, Haro, J, Hasaballah, A, Hasan, M, Hashi, A, Hay, S, Hayat, K, Heidari, M, Heidari, G, Henry, N, Herteliu, C, Holla, R, Hossain, S, Hossain, M, Hosseinzadeh, M, Hostiuc, S, Hoveidamanesh, S, Hsieh, V, Hu, G, Huang, J, Huda, M, Ifeagwu, S, Ikuta, K, Ilesanmi, O, Irvani, S, Islam, R, Islam, S, Ismail, N, Iso, H, Isola, G, Itumalla, R, Iwagami, M, Jahani, M, Jahanmehr, N, Jain, R, Jakovljevic, M, Janodia, M, Jayapal, S, Jayaram, S, Jha, R, Jonas, J, Joo, T, Joseph, N, Jurisson, M, Kabir, A, Kalankesh, L, Kalhor, R, Kamath, A, Kamenov, K, Kandel, H, Kantar, R, Kapoor, N, Karanikolos, M, Katikireddi, S, Kavetskyy, T, Kawakami, N, Kayode, G, Keikavoosi-Arani, L, Keykhaei, M, Khader, Y, Khajuria, H, Khalilov, R, Khammarnia, M, Khan, M, Khezeli, M, Kim, M, Kim, Y, Kisa, S, Kisa, A, Klymchuk, V, Koly, K, Korzh, O, Kosen, S, Koul, P, Kuate Defo, B, Kumar, G, Kusuma, D, Kyu, H, Larsson, A, Lasrado, S, Lee, W, Lee, Y, Lee, C, Li, S, Lucchetti, G, Mahajan, P, Majeed, A, Makki, A, Malekzadeh, R, Malik, A, Malta, D, Mansournia, M, Mantovani, L, Martinez-Valle, A, Martins-Melo, F, Masoumi, S, Mathur, M, Maude, R, Maulik, P, Mckee, M, Mendoza, W, Menezes, R, Mensah, G, Meretoja, A, Meretoja, T, Mestrovic, T, Michalek, I, Mirrakhimov, E, Misganaw, A, Misra, S, Moazen, B, Mohammadi, M, Mohammed, S, Moitra, M, Mokdad, A, Molokhia, M, Monasta, L, Moni, M, Moradi, G, Moreira, R, Mosser, J, Mostafavi, E, Mouodi, S, Nagarajan, A, Nagata, C, Naghavi, M, Nangia, V, Narasimha Swamy, S, Narayana, A, Nascimento, B, Nassereldine, H, Nayak, B, Nazari, J, Negoi, I, Nepal, S, Neupane Kandel, S, Ngunjiri, J, Nguyen, H, Nguyen, C, Ningrum, D, Noubiap, J, Oancea, B, Oghenetega, O, Oh, I, Olagunju, A, Olakunde, B, Omar Bali, A, Omer, E, Onwujekwe, O, Otoiu, A, Padubidri, J, Palladino, R, Pana, A, Panda-Jonas, S, Pandi-Perumal, S, Pardhan, S, Pasupula, D, Pathak, P, Patton, G, Pawar, S, Pereira, J, Pilania, M, Piroozi, B, Podder, V, Pokhrel, K, Postma, M, Prada, S, Quazi Syed, Z, Rabiee, N, Radhakrishnan, R, Rahman, M, Rahmani, A, Ranabhat, C, Rao, C, Rao, S, Rasella, D, Rawaf, S, Rawaf, D, Rawal, L, Renzaho, A, Reshmi, B, Resnikoff, S, Rezapour, A, Riahi, S, Ripon, R, Sacco, S, Sadeghi, M, Saeed, U, Sahebkar, A, Sahiledengle, B, Sahoo, H, Sahu, M, Salama, J, Salamati, P, Samy, A, Sanabria, J, Santric-Milicevic, M, Sathian, B, Sawhney, M, Schmidt, M, Seidu, A, Sepanlou, S, Seylani, A, Shaikh, M, Sheikh, A, Shetty, A, Shigematsu, M, Shiri, R, Shivakumar, K, Shokri, A, Singh, J, Sinha, D, Skryabin, V, Skryabina, A, Sofi-Mahmudi, A, Sousa, R, Stephens, J, Sun, J, Szocska, M, Tabares-Seisdedos, R, Tadbiri, H, Tamiru, A, Thankappan, K, Topor-Madry, R, Tovani-Palone, M, Tran, M, Tran, B, Tripathi, N, Tripathy, J, Troeger, C, Uezono, D, Ullah, S, Ullah, A, Unnikrishnan, B, Vacante, M, Valadan Tahbaz, S, Valdez, P, Vasic, M, Veroux, M, Vervoort, D, Violante, F, Vladimirov, S, Vlassov, V, Vo, B, Waheed, Y, Wamai, R, Wang, Y, Ward, P, Wiangkham, T, Yadav, L, Yahyazadeh Jabbari, S, Yamagishi, K, Yaya, S, Yazdi-Feyzabadi, V, Yi, S, Yigit, V, Yonemoto, N, Younis, M, Yu, C, Yunusa, I, Zaman, S, Zastrozhin, M, Zhang, Z, Zhong, C, Zuniga, Y, Lim, S, Murray, C, Lozano, R, Bill & Melinda Gates Foundation, King Edward Medical University (Pakistán), Kuwait University (Kuwait), Romanian National Authority for Scientific Research and Innovation, Romanian Ministry of Research Innovation and Digitalization, Alexander von Humboldt Foundation, Federal Ministry of Education & Research (Alemania), Unión Europea. Comisión Europea. H2020, University of Aberdeen (Reino Unido), Novo Nordisk Foundation, National Health and Medical Research Council (Australia), National Research, Development and Innovation Office (Hungria), National Records of Scotland (Reino Unido), Medical Research Council (Reino Unido), Scottish Government (Reino Unido), Jatiya Kabi Kazi Nazrul Islam University (Bangladesh), Xiamen University Malaysia (Malasia), National Council for Scientific and Technological Development (Brasil), Ministero della Salute (Italia), Fondazione IRCCS. Istituto Nazionale dei Tumori, King College London, IRCCS Materno Infantile Burlo Garofolo (Italia), Edwards Lifesciences Foundation, Fundação de Amparo à Pesquisa do Estado de Minas Gerais (Brasil), Manipal Academy of Higher Education (India), Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España), Government of Catalonia (España), International Center of Medical Sciences Research (Pakistán), Ain Shams University (Egipto), Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red - CIBERSAM (Salud Mental), INCLIVA Health Research Institute (España), Canadian Institutes of Health Research, Australian Government, and Ministry of Education, Science and Technological Development (Serbia)
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Adult ,Adolescent ,Population ,Global Health ,Health Services Accessibility ,Global Burden of Disease ,Health system quality ,Young Adult ,Nations ,Health systems ,health care access ,Risk Factors ,Quality-Adjusted Life Year ,Humans ,Child ,Global Burden of Disease Study 2019 ,Health-care access ,Aged ,Quality of Health Care ,quality ,performance ,The Healthcare Access and Quality Index ,Risk Factor ,Infant, Newborn ,Infant ,eu-repo/semantics/review [info] ,Public Health, Global Health, Social Medicine and Epidemiology ,General Medicine ,Health-care quality ,Middle Aged ,3141 Health care science ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Indicator ,Medical-care ,Child, Preschool ,Deaths ,Amenable mortality ,Quality-Adjusted Life Years ,Age groups ,Trends ,Human - Abstract
Background: Health-care needs change throughout the life course. It is thus crucial to assess whether health systems provide access to quality health care for all ages. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019), we measured the Healthcare Access and Quality (HAQ) Index overall and for select age groups in 204 locations from 1990 to 2019. Methods: We distinguished the overall HAQ Index (ages 0-74 years) from scores for select age groups: the young (ages 0-14 years), working (ages 15-64 years), and post-working (ages 65-74 years) groups. For GBD 2019, HAQ Index construction methods were updated to use the arithmetic mean of scaled mortality-to-incidence ratios (MIRs) and risk-standardised death rates (RSDRs) for 32 causes of death that should not occur in the presence of timely, quality health care. Across locations and years, MIRs and RSDRs were scaled from 0 (worst) to 100 (best) separately, putting the HAQ Index on a different relative scale for each age group. We estimated absolute convergence for each group on the basis of whether the HAQ Index grew faster in absolute terms between 1990 and 2019 in countries with lower 1990 HAQ Index scores than countries with higher 1990 HAQ Index scores and by Socio-demographic Index (SDI) quintile. SDI is a summary metric of overall development. Findings: Between 1990 and 2019, the HAQ Index increased overall (by 19·6 points, 95% uncertainty interval 17·9-21·3), as well as among the young (22·5, 19·9-24·7), working (17·2, 15·2-19·1), and post-working (15·1, 13·2-17·0) age groups. Large differences in HAQ Index scores were present across SDI levels in 2019, with the overall index ranging from 30·7 (28·6-33·0) on average in low-SDI countries to 83·4 (82·4-84·3) on average in high-SDI countries. Similarly large ranges between low-SDI and high-SDI countries, respectively, were estimated in the HAQ Index for the young (40·4-89·0), working (33·8-82·8), and post-working (30·4-79·1) groups. Absolute convergence in HAQ Index was estimated in the young group only. In contrast, divergence was estimated among the working and post-working groups, driven by slow progress in low-SDI countries. Interpretation: Although major gaps remain across levels of social and economic development, convergence in the young group is an encouraging sign of reduced disparities in health-care access and quality. However, divergence in the working and post-working groups indicates that health-care access and quality is lagging at lower levels of social and economic development. To meet the needs of ageing populations, health systems need to improve health-care access and quality for working-age adults and older populations while continuing to realise gains among the young. O Adetokunboh acknowledges support from Department of Science and Innovation and National Research Foundation. S Afzal acknowledges the institutional support of King Edward Medical University. S Aljunid acknowledges Department of Health Policy and Management, College of Public Health, Health Science Centre, Kuwait University for the approval and support to participate in this research project. M Ausloos, C Herteliu, and A Pana acknowledge partial support by a grant of the Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI, project number PN-III-P4-ID-PCCF-2016-0084. C Herteliu also acknowledges partial support by a grant of the Romanian Ministry of Research Innovation and Digitalization, MCID, project number ID-585-CTR-42-PFE-2021. T Bärnighausen was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, funded by the Federal Ministry of Education and Research. B Bikbov acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement No. 703226. Institute of Applied Health Sciences; School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Scotland. The salary for N Ghith is covered by a grant from Novo Nordisk Foundation (NNF16OC0021856). V B Gupta acknowledges funding support from National Health and Medical Research Council (NHMRC) Australia. V K Gupta acknowledges funding support from National Health and Medical Research Council (NHMRC) Australia. T Joo acknowledges support from the National Research, Development and Innovation Office of Hungary under grant RRF-2.3.1-21-2022-00006 (Data-driven Health Division of Health Security National Laboratory). S Vittal Katikireddi acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC_UU_00022/2), and the Scottish Government Chief Scientist Office (SPHSU17). M N Khan acknowledges the support of Jatiya Kabi Kazi Nazrul Islam University, Mymensingh, Bangladesh. Y J Kim acknowledges support from the Research Management Centre Xiamen University Malaysia [XMUMRF/2020-C6/ITCM/0004]. G Lucchetti is a grantee of the Brazilian National Council for Scientific and Technological Development Research Productivity - Level 1D. L Mantovani acknowledges support by Italian Ministry of Health Ricerca Corrente - IRCCS Multimedica. M Molokhia acknowledges support by the National Institute for Health Research Biomedical Research Center at Guy’s and St Thomas’ National Health Service Foundation Trust and King’s College London. L Monasta reports support for the present manuscript from the Italian Ministry of Health on project Ricerca Corrente 34/2017 and payments made to the Institute for Maternal and Child Health IRCCS Burlo Garofolo. R Moreira acknowledges the CNPQ productivity grant (316607/2021-5). B R Nascimento is partially supported by CNPq (Research Productivity Grant, 312382/2019-7), the Edwards Lifesciences Foundation (Improving the prevention and detection of Heart Valve disease across the Lifespan, 2021), and FAPEMIG (grant APQ-000627-20). J R Padubidri acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India for their constant support in conducting research. D Rasella reports financial support from the Spanish Ministry of Science and Innovation and State Research Agency through the Centro de Excelencia Severo Ochoa 2019-2023 programme (CEX2018-000806-S), and financial support from the Generalitat de Catalunya through the Centres de Recerca de Catalunya programme. U Saeed would like to acknowledge the International Center of Medical Sciences Research (ICMSR), Islamabad (44000), Pakistan. A M Samy acknowledges the support from Ain Shams University and the Egyptian Fulbright Mission Program. U Saeed would like to acknowledge Kasturba Medical College, Mangalore. Manipal Academy of Higher Education, Manipal for supporting research activities. R T-S is supported by the Spanish Ministry of Science and Innovation, Institute of Health Carlos III, CIBERSAM, INCLIVA (PID2021-129099OB-I00). D Vervoort is supported by the Canadian Institutes of Health Research (CIHR) Vanier Canada Graduate Scholarship. S B Zaman acknowledges receiving a scholarship from the Australian Government Research Training Program (RTP) in support of his academic career. Serbian part of this GBD contribution was co-financed through Grant OI 175 014 of the Ministry of Education Science and Technological Development of The Republic of Serbia. This work was supported, in whole or in part, by the Bill & Melinda Gates Foundation OPP1152504. Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned to the Author Accepted Manuscript version that might arise from this submission. Sí
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- 2022
14. Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019
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Reitsma, Marissa B., Kendrick, Parkes J., Ababneh, Emad, Abbafati, Cristiana, Abbasi-Kangevari, Mohsen, Abdoli, Amir, Abedi, Aidin, Abhilash, E.S., Abila, Derrick Bary, Aboyans, Victor, Abu-Rmeileh, Niveen M.E., Adebayo, Oladimeji M., Advani, Shailesh M., Aghaali, Mohammad, Ahinkorah, Bright Opoku, Ahmad, Sohail, Ahmadi, Keivan, Ahmed, Haroon, Aji, Budi, Akunna, Chisom Joyqueenet, Al-Aly, Ziyad, Alanzi, Turki M., Alhabib, Khalid F., Ali, Liaqat, Alif, Sheikh Mohammad, Alipour, Vahid, Aljunid, Syed Mohamed, Alla, François, Allebeck, Peter, Alvis-Guzman, Nelson, Amin, Tarek Tawfik, Amini, Saeed, Amu, Hubert, Amul, Gianna Gayle Herrera, Ancuceanu, Robert, Anderson, Jason A., Ansari-Moghaddam, Alireza, Antonio, Carl Abelardo T., Antony, Benny, Anvari, Davood, Arabloo, Jalal, Arian, Nicholas D., Arora, Monika, Asaad, Malke, Ausloos, Marcel, Awan, Asma Tahir, Ayano, Getinet, Aynalem, Getie Lake, Azari, Samad, B, Darshan B., Badiye, Ashish D., Baig, Atif Amin, Bakhshaei, Mohammad Hossein, Banach, Maciej, Banik, Palash Chandra, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barqawi, Hiba Jawdat, Basu, Sanjay, Bayati, Mohsen, Bazargan-Hejazi, Shahrzad, Behzadifar, Masoud, Bekuma, Tariku Tesfaye, Bennett, Derrick A., Bensenor, Isabela M., Berfield, Kathleen S. Sachiko, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bibi, Sadia, Bijani, Ali, Bintoro, Bagas Suryo, Biondi, Antonio, Birara, Setognal, Braithwaite, Dejana, Brenner, Hermann, Brunoni, Andre R., Burkart, Katrin, Butt, Zahid A., Caetano dos Santos, Florentino Luciano, Cámera, Luis Alberto, Car, Josip, Cárdenas, Rosario, Carreras, Giulia, Carrero, Juan J., Castaldelli-Maia, Joao Mauricio, Cattaruzza, Maria Sofia Sofia, Chang, Jung-Chen, Chen, Simiao, Chu, Dinh-Toi, Chung, Sheng-Chia, Cirillo, Massimo, Costa, Vera Marisa, Couto, Rosa A.S., Dadras, Omid, Dai, Xiaochen, Damasceno, Albertino Antonio Moura, Damiani, Giovanni, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Darega Gela, Jiregna, Davletov, Kairat, Derbew Molla, Meseret, Dessie, Getenet Ayalew, Desta, Abebaw Alemayehu, Dharmaratne, Samath Dhamminda, Dianatinasab, Mostafa, Diaz, Daniel, Do, Hoa Thi, Douiri, Abdel, Duncan, Bruce B., Duraes, Andre Rodrigues, Eagan, Arielle Wilder, Ebrahimi Kalan, Mohammad, Edvardsson, Kristina, Elbarazi, Iffat, El Tantawi, Maha, Esmaeilnejad, Saman, Fadhil, Ibtihal, Faraon, Emerito Jose A., Farinha, Carla Sofia e Sá, Farwati, Medhat, Farzadfar, Farshad, Fazlzadeh, Mehdi, Feigin, Valery L., Feldman, Rachel, Fernandez Prendes, Carlota, Ferrara, Pietro, Filip, Irina, Filippidis, Filippos, Fischer, Florian, Flor, Luisa Sorio, Foigt, Nataliya A., Folayan, Morenike Oluwatoyin, Foroutan, Masoud, Gad, Mohamed M., Gaidhane, Abhay Motiramji, Gallus, Silvano, Geberemariyam, Biniyam Sahiledengle, Ghafourifard, Mansour, Ghajar, Alireza, Ghashghaee, Ahmad, Giampaoli, Simona, Gill, Paramjit Singh, Glozah, Franklin N., Gnedovskaya, Elena V., Golechha, Mahaveer, Gopalani, Sameer Vali, Gorini, Giuseppe, Goudarzi, Houman, Goulart, Alessandra C., Greaves, Felix, Guha, Avirup, Guo, Yuming, Gupta, Bhawna, Gupta, Rajat Das, Gupta, Rajeev, Gupta, Tarun, Gupta, Vin, Hafezi-Nejad, Nima, Haider, Mohammad Rifat, Hamadeh, Randah R., Hankey, Graeme J., Hargono, Arief, Hartono, Risky Kusuma, Hassankhani, Hadi, Hay, Simon I., Heidari, Golnaz, Herteliu, Claudiu, Hezam, Kamal, Hird, Thomas R., Hole, Michael K., Holla, Ramesh, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Househ, Mowafa, Hsiao, Thomas, Huang, Junjie, Iannucci, Vincent C., Ibitoye, Segun Emmanuel, Idrisov, Bulat, Ilesanmi, Olayinka Stephen, Ilic, Irena M., Ilic, Milena D., Inbaraj, Leeberk Raja, Irvani, Seyed Sina Naghibi, Islam, Jessica Y., Islam, Rakibul M., Islam, Sheikh Mohammed Shariful, Islami, Farhad, Iso, Hiroyasu, Itumalla, Ramaiah, Iwagami, Masao, Jaafari, Jalil, Jain, Vardhmaan, Jakovljevic, Mihajlo, Jang, Sung-In, Janjani, Hosna, Jayaram, Shubha, Jeemon, Panniyammakal, Jha, Ravi Prakash, Jonas, Jost B., Joo, Tamas, Jürisson, Mikk, Kabir, Ali, Kabir, Zubair, Kalankesh, Leila R., Kanchan, Tanuj, Kandel, Himal, Kapoor, Neeti, Karimi, Salah Eddin, Katikireddi, rinivasa Vittal, Kebede, Hafte Kahsay, Kelkay, Bayew, Kennedy, Ryan David, Khoja, Abdullah T., Khubchandani, Jagdish, Kim, Gyu Ri, Kim, Young-Eun, Kimokoti, Ruth W., Kivimäki, Mika, Kosen, Soewarta, Koulmane Laxminarayana, Sindhura Lakshmi, Koyanagi, Ai, Krishan, Kewal, Kugbey, Nuworza, Kumar, G. Anil, Kumar, Nithin, Kurmi, Om P., Kusuma, Dian, Lacey, Ben, Lam, Jennifer O., Landires, Iván, Lasrado, Savita, Lauriola, Paolo, Lee, Doo Woong, Lee, Yo Han, Leung, Janni, Li, Shanshan, Lin, Hualiang, Linn, Shai, Liu, Wei, Lopez, Alan D., Lopukhov, Platon D., Lorkowski, Stefan, Lugo, Alessandra, Majeed, Azeem, Maleki, Afshin, Malekzadeh, Reza, Malta, Deborah Carvalho, Mamun, Abdullah A., Manjunatha, Narayana, Mansouri, Borhan, Mansournia, Mohammad Ali, Martinez-Raga, Jose, Martini, Santi, Mathur, Manu Raj, Medina-Solís, Carlo Eduardo, Mehata, Suresh, Mendoza, Walter, Menezes, Ritesh G., Meretoja, Atte, Meretoja, Tuomo J., Miazgowski, Bartosz, Michalek, Irmina Maria, Miller, Ted R., Mirrakhimov, Erkin M., Mirzaei, Hamed, Mirzaei-Alavijeh, Mehdi, Misra, Sanjeev, Moghadaszadeh, Masoud, Mohammad, Yousef, Mohammadian-Hafshejani, Abdollah, Mohammed, Shafiu, Mokdad, Ali H., Monasta, Lorenzo, Moni, Mohammad Ali, Moradi, Ghobad, Moradi-Lakeh, Maziar, Moradzadeh, Rahmatollah, Morrison, Shane Douglas, Mossie, Tilahun Belete, Mubarik, Sumaira, Mullany, Erin C., Murray, Christopher J.L., Naghavi, Mohsen, Naghshtabrizi, Behshad, Nair, Sanjeev, Nalini, Mahdi, Nangia, Vinay, Naqvi, Atta Abbas, Narasimha Swamy, Sreenivas, Naveed, Muhammad, Nayak, Smitha, Nayak, Vinod C., Nazari, Javad, Nduaguba, Sabina O., Neupane Kandel, Sandhya, Nguyen, Cuong Tat, Nguyen, Huong Lan Thi, Nguyen, Son Hoang, Nguyen, Trang Huyen, Nixon, Molly R., Nnaji, Chukwudi A., Norrving, Bo, Noubiap, Jean Jacques, Nowak, Christoph, Ogbo, Felix Akpojene, Oguntade, Ayodipupo Sikiru, Oh, In-Hwan, Olagunju, Andrew T., Oren, Eyal, Otstavnov, Nikita, Otstavnov, Stanislav S., Owolabi, Mayowa O., P A, Mahesh, Pakhale, Smita, Pakshir, Keyvan, Palladino, Raffaele, Pan, Liping, Pana, Adrian, Panda-Jonas, Songhomitra, Pandey, Ashok, Parekh, Utsav, Park, Eun-Cheol, Park, Eun-Kee, Pashazadeh Kan, Fatemeh, Patton, George C., Pawar, Shrikant, Pestell, Richard G., Pinheiro, Marina, Piradov, Michael A., Pirouzpanah, Saeed, Pokhrel, Khem Narayan, Polibin, Roman V., Prashant, Akila, Pribadi, Dimas Ria Angga, Radfar, Amir, Rahimi-Movaghar, Vafa, Rahman, Azizur, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rajai, Nazanin, Ram, Pradhum, Ranabhat, Chhabi Lal, Rathi, Priya, Rawal, Lal, Renzaho, Andre M.N., Reynales-Shigematsu, Luz Myriam, Rezapour, Aziz, Riahi, Seyed Mohammad, Riaz, Mavra A., Roever, Leonardo, Ronfani, Luca, Roshandel, Gholamreza, Roy, Ambuj, Roy, Bedanta, Sacco, Simona, Saddik, Basema, Sahebkar, Amirhossein, Salehi, Sana, Salimzadeh, Hamideh, Samaei, Mehrnoosh, Samy, Abdallah M., Santos, Itamar S., Santric-Milicevic, Milena M., Sarrafzadegan, Nizal, Sathian, Brijesh, Sawhney, Monika, Saylan, Mete, Schaub, Michael P., Schmidt, Maria Inês, Schneider, Ione Jayce Ceola, Schutte, Aletta Elisabeth, Schwendicke, Falk, Seidu, Abdul-Aziz, Senthil Kumar, Nachimuthu, Sepanlou, Sadaf G., Seylani, Allen, Shafaat, Omid, Shah, Syed Mahboob, Shaikh, Masood Ali, Shalash, Ali S., Shannawaz, Mohammed, Sharafi, Kiomars, Sheikh, Aziz, Sheikhbahaei, Sara, Shigematsu, Mika, Shiri, Rahman, Shishani, Kawkab, Shivakumar, K.M., Shivalli, Siddharudha, Shrestha, Roman, Siabani, Soraya, Sidemo, Negussie Boti, Sigfusdottir, Inga Dora, Sigurvinsdottir, Rannveig, Silva, Diego Augusto Santos, Silva, João Pedro, Singh, Ambrish, Singh, Jasvinder A., Singh, Virendra, Sinha, Dhirendra Narain, Sitas, Freddy, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Soboka, Matiwos, Soriano, Joan B., Soroush, Ali, Soshnikov, Sergey, Soyiri, Ireneous N., Spurlock, Emma Elizabeth, Sreeramareddy, Chandrashekhar T., Stein, Dan J, Steiropoulos, Paschalis, Stortecky, Stefan, Straif, Kurt, Suliankatchi Abdulkader, Rizwan, Sulo, Gerhard, Sundström, Johan, Tabuchi, Takahiro, Tadakamadla, Santosh Kumar, Taddele, Biruk Wogayehu, Tadesse, Eyayou Girma, Tamiru, Animut Tagele, Tareke, Minale, Tareque, Md Ismail, Tarigan, Ingan Ukur, Temsah, Mohamad-Hani, Thankappan, Kavumpurathu Raman, Thapar, Rekha, Tichopad, Ales, Tolani, Musliu Adetola, Topouzis, Fotis, Tovani-Palone, Marcos Roberto, Tran, Bach Xuan, Tripathy, Jaya Prasad, Tsegaye, Gebiyaw Wudie, Tsilimparis, Nikolaos, Tymeson, Hayley D., Ullah, Anayat, Ullah, Saif, Unim, Brigid, Updike, Rachel L., Vacante, Marco, Valdez, Pascual R., Vardavas, Constantine, Varona Pérez, Patricia, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Verma, Madhur, Vetrova, Marina V., Vo, Bay, Vu, Giang Thu, Waheed, Yasir, Wang, Yanzhong, Welding, Kevin, Werdecker, Andrea, Whisnant, Joanna L., Wickramasinghe, Nuwan Darshana, Yamagishi, Kazumasa, Yandrapalli, Srikanth, Yatsuya, Hiroshi, Yazdi-Feyzabadi, Vahid, Yeshaw, Yigizie, Yimmer, Mohammed Zewdu, Yonemoto, Naohiro, Yu, Chuanhua, Yunusa, Ismaeel, Yusefzadeh, Hasan, Zahirian Moghadam, Telma, Zaman, Muhammed Shahriar, Zamanian, Maryam, Zandian, Hamed, Zar, Heather J., Zastrozhin, Mikhail Sergeevich, Zastrozhina, Anasthasia, Zavala-Arciniega, Luis, Zhang, Jianrong, Zhang, Zhi-Jiang, Zhong, Chenwen, Zuniga, Yves Miel H., Gakidou, Emmanuela, Reitsma, Marissa B, Kendrick, Parkes J, Ababneh, Emad, Abbafati, Cristiana, Abbasi-Kangevari, Mohsen, Abdoli, Amir, Abedi, Aidin, Abhilash, E S, Abila, Derrick Bary, Aboyans, Victor, Abu-Rmeileh, Niveen ME, Adebayo, Oladimeji M, Advani, Shailesh M, Aghaali, Mohammad, Ahinkorah, Bright Opoku, Ahmad, Sohail, Ahmadi, Keivan, Ahmed, Haroon, Aji, Budi, Akunna, Chisom Joyqueenet, Al-Aly, Ziyad, Alanzi, Turki M, Alhabib, Khalid F, Ali, Liaqat, Alif, Sheikh Mohammad, Alipour, Vahid, Aljunid, Syed Mohamed, Alla, Françoi, Allebeck, Peter, Alvis-Guzman, Nelson, Amin, Tarek Tawfik, Amini, Saeed, Amu, Hubert, Amul, Gianna Gayle Herrera, Ancuceanu, Robert, Anderson, Jason A, Ansari-Moghaddam, Alireza, Antonio, Carl Abelardo T, Antony, Benny, Anvari, Davood, Arabloo, Jalal, Arian, Nicholas D, Arora, Monika, Asaad, Malke, Ausloos, Marcel, Awan, Asma Tahir, Ayano, Getinet, Aynalem, Getie Lake, Azari, Samad, B, Darshan B, Badiye, Ashish D, Baig, Atif Amin, Bakhshaei, Mohammad Hossein, Banach, Maciej, Banik, Palash Chandra, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barqawi, Hiba Jawdat, Basu, Sanjay, Bayati, Mohsen, Bazargan-Hejazi, Shahrzad, Behzadifar, Masoud, Bekuma, Tariku Tesfaye, Bennett, Derrick A, Bensenor, Isabela M, Berfield, Kathleen S Sachiko, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bibi, Sadia, Bijani, Ali, Bintoro, Bagas Suryo, Biondi, Antonio, Birara, Setognal, Braithwaite, Dejana, Brenner, Hermann, Brunoni, Andre R, Burkart, Katrin, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cámera, Luis Alberto, Car, Josip, Cárdenas, Rosario, Carreras, Giulia, Carrero, Juan J, Castaldelli-Maia, Joao Mauricio, Cattaruzza, Maria Sofia Sofia, Chang, Jung-Chen, Chen, Simiao, Chu, Dinh-Toi, Chung, Sheng-Chia, Cirillo, Massimo, Costa, Vera Marisa, Couto, Rosa A S, Dadras, Omid, Dai, Xiaochen, Damasceno, Albertino Antonio Moura, Damiani, Giovanni, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Darega Gela, Jiregna, Davletov, Kairat, Derbew Molla, Meseret, Dessie, Getenet Ayalew, Desta, Abebaw Alemayehu, Dharmaratne, Samath Dhamminda, Dianatinasab, Mostafa, Diaz, Daniel, Do, Hoa Thi, Douiri, Abdel, Duncan, Bruce B, Duraes, Andre Rodrigue, Eagan, Arielle Wilder, Ebrahimi Kalan, Mohammad, Edvardsson, Kristina, Elbarazi, Iffat, El Tantawi, Maha, Esmaeilnejad, Saman, Fadhil, Ibtihal, Faraon, Emerito Jose A, Farinha, Carla Sofia e Sá, Farwati, Medhat, Farzadfar, Farshad, Fazlzadeh, Mehdi, Feigin, Valery L, Feldman, Rachel, Fernandez Prendes, Carlota, Ferrara, Pietro, Filip, Irina, Filippidis, Filippo, Fischer, Florian, Flor, Luisa Sorio, Foigt, Nataliya A, Folayan, Morenike Oluwatoyin, Foroutan, Masoud, Gad, Mohamed M, Gaidhane, Abhay Motiramji, Gallus, Silvano, Geberemariyam, Biniyam Sahiledengle, Ghafourifard, Mansour, Ghajar, Alireza, Ghashghaee, Ahmad, Giampaoli, Simona, Gill, Paramjit Singh, Glozah, Franklin N, Gnedovskaya, Elena V, Golechha, Mahaveer, Gopalani, Sameer Vali, Gorini, Giuseppe, Goudarzi, Houman, Goulart, Alessandra C, Greaves, Felix, Guha, Avirup, Guo, Yuming, Gupta, Bhawna, Gupta, Rajat Da, Gupta, Rajeev, Gupta, Tarun, Gupta, Vin, Hafezi-Nejad, Nima, Haider, Mohammad Rifat, Hamadeh, Randah R, Hankey, Graeme J, Hargono, Arief, Hartono, Risky Kusuma, Hassankhani, Hadi, Hay, Simon I, Heidari, Golnaz, Herteliu, Claudiu, Hezam, Kamal, Hird, Thomas R, Hole, Michael K, Holla, Ramesh, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Househ, Mowafa, Hsiao, Thoma, Huang, Junjie, Iannucci, Vincent C, Ibitoye, Segun Emmanuel, Idrisov, Bulat, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Inbaraj, Leeberk Raja, Irvani, Seyed Sina Naghibi, Islam, Jessica Y, Islam, Rakibul M, Islam, Sheikh Mohammed Shariful, Islami, Farhad, Iso, Hiroyasu, Itumalla, Ramaiah, Iwagami, Masao, Jaafari, Jalil, Jain, Vardhmaan, Jakovljevic, Mihajlo, Jang, Sung-In, Janjani, Hosna, Jayaram, Shubha, Jeemon, Panniyammakal, Jha, Ravi Prakash, Jonas, Jost B, Joo, Tama, Jürisson, Mikk, Kabir, Ali, Kabir, Zubair, Kalankesh, Leila R, Kanchan, Tanuj, Kandel, Himal, Kapoor, Neeti, Karimi, Salah Eddin, Katikireddi, Srinivasa Vittal, Kebede, Hafte Kahsay, Kelkay, Bayew, Kennedy, Ryan David, Khoja, Abdullah T, Khubchandani, Jagdish, Kim, Gyu Ri, Kim, Young-Eun, Kimokoti, Ruth W, Kivimäki, Mika, Kosen, Soewarta, Koulmane Laxminarayana, Sindhura Lakshmi, Koyanagi, Ai, Krishan, Kewal, Kugbey, Nuworza, Kumar, G Anil, Kumar, Nithin, Kurmi, Om P, Kusuma, Dian, Lacey, Ben, Lam, Jennifer O, Landires, Iván, Lasrado, Savita, Lauriola, Paolo, Lee, Doo Woong, Lee, Yo Han, Leung, Janni, Li, Shanshan, Lin, Hualiang, Linn, Shai, Liu, Wei, Lopez, Alan D, Lopukhov, Platon D, Lorkowski, Stefan, Lugo, Alessandra, Majeed, Azeem, Maleki, Afshin, Malekzadeh, Reza, Malta, Deborah Carvalho, Mamun, Abdullah A, Manjunatha, Narayana, Mansouri, Borhan, Mansournia, Mohammad Ali, Martinez-Raga, Jose, Martini, Santi, Mathur, Manu Raj, Medina-Solís, Carlo Eduardo, Mehata, Suresh, Mendoza, Walter, Menezes, Ritesh G, Meretoja, Atte, Meretoja, Tuomo J, Miazgowski, Bartosz, Michalek, Irmina Maria, Miller, Ted R, Mirrakhimov, Erkin M, Mirzaei, Hamed, Mirzaei-Alavijeh, Mehdi, Misra, Sanjeev, Moghadaszadeh, Masoud, Mohammad, Yousef, Mohammadian-Hafshejani, Abdollah, Mohammed, Shafiu, Mokdad, Ali H, Monasta, Lorenzo, Moni, Mohammad Ali, Moradi, Ghobad, Moradi-Lakeh, Maziar, Moradzadeh, Rahmatollah, Morrison, Shane Dougla, Mossie, Tilahun Belete, Mubarik, Sumaira, Mullany, Erin C, Murray, Christopher J L, Naghavi, Mohsen, Naghshtabrizi, Behshad, Nair, Sanjeev, Nalini, Mahdi, Nangia, Vinay, Naqvi, Atta Abba, Narasimha Swamy, Sreeniva, Naveed, Muhammad, Nayak, Smitha, Nayak, Vinod C, Nazari, Javad, Nduaguba, Sabina O, Neupane Kandel, Sandhya, Nguyen, Cuong Tat, Nguyen, Huong Lan Thi, Nguyen, Son Hoang, Nguyen, Trang Huyen, Nixon, Molly R, Nnaji, Chukwudi A, Norrving, Bo, Noubiap, Jean Jacque, Nowak, Christoph, Ogbo, Felix Akpojene, Oguntade, Ayodipupo Sikiru, Oh, In-Hwan, Olagunju, Andrew T, Oren, Eyal, Otstavnov, Nikita, Otstavnov, Stanislav S, Owolabi, Mayowa O, P A, Mahesh, Pakhale, Smita, Pakshir, Keyvan, Palladino, Raffaele, Pan, Liping, Pana, Adrian, Panda-Jonas, Songhomitra, Pandey, Ashok, Parekh, Utsav, Park, Eun-Cheol, Park, Eun-Kee, Pashazadeh Kan, Fatemeh, Patton, George C, Pawar, Shrikant, Pestell, Richard G, Pinheiro, Marina, Piradov, Michael A, Pirouzpanah, Saeed, Pokhrel, Khem Narayan, Polibin, Roman V, Prashant, Akila, Pribadi, Dimas Ria Angga, Radfar, Amir, Rahimi-Movaghar, Vafa, Rahman, Azizur, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rajai, Nazanin, Ram, Pradhum, Ranabhat, Chhabi Lal, Rathi, Priya, Rawal, Lal, Renzaho, Andre M N, Reynales-Shigematsu, Luz Myriam, Rezapour, Aziz, Riahi, Seyed Mohammad, Riaz, Mavra A, Roever, Leonardo, Ronfani, Luca, Roshandel, Gholamreza, Roy, Ambuj, Roy, Bedanta, Sacco, Simona, Saddik, Basema, Sahebkar, Amirhossein, Salehi, Sana, Salimzadeh, Hamideh, Samaei, Mehrnoosh, Samy, Abdallah M, Santos, Itamar S, Santric-Milicevic, Milena M, Sarrafzadegan, Nizal, Sathian, Brijesh, Sawhney, Monika, Saylan, Mete, Schaub, Michael P, Schmidt, Maria Inê, Schneider, Ione Jayce Ceola, Schutte, Aletta Elisabeth, Schwendicke, Falk, Seidu, Abdul-Aziz, Senthil Kumar, Nachimuthu, Sepanlou, Sadaf G, Seylani, Allen, Shafaat, Omid, Shah, Syed Mahboob, Shaikh, Masood Ali, Shalash, Ali S, Shannawaz, Mohammed, Sharafi, Kiomar, Sheikh, Aziz, Sheikhbahaei, Sara, Shigematsu, Mika, Shiri, Rahman, Shishani, Kawkab, Shivakumar, K M, Shivalli, Siddharudha, Shrestha, Roman, Siabani, Soraya, Sidemo, Negussie Boti, Sigfusdottir, Inga Dora, Sigurvinsdottir, Rannveig, Silva, Diego Augusto Santo, Silva, João Pedro, Singh, Ambrish, Singh, Jasvinder A, Singh, Virendra, Sinha, Dhirendra Narain, Sitas, Freddy, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Soboka, Matiwo, Soriano, Joan B, Soroush, Ali, Soshnikov, Sergey, Soyiri, Ireneous N, Spurlock, Emma Elizabeth, Sreeramareddy, Chandrashekhar T, Stein, Dan J, Steiropoulos, Paschali, Stortecky, Stefan, Straif, Kurt, Suliankatchi Abdulkader, Rizwan, Sulo, Gerhard, Sundström, Johan, Tabuchi, Takahiro, Tadakamadla, Santosh Kumar, Taddele, Biruk Wogayehu, Tadesse, Eyayou Girma, Tamiru, Animut Tagele, Tareke, Minale, Tareque, Md Ismail, Tarigan, Ingan Ukur, Temsah, Mohamad-Hani, Thankappan, Kavumpurathu Raman, Thapar, Rekha, Tichopad, Ale, Tolani, Musliu Adetola, Topouzis, Foti, Tovani-Palone, Marcos Roberto, Tran, Bach Xuan, Tripathy, Jaya Prasad, Tsegaye, Gebiyaw Wudie, Tsilimparis, Nikolao, Tymeson, Hayley D, Ullah, Anayat, Ullah, Saif, Unim, Brigid, Updike, Rachel L, Vacante, Marco, Valdez, Pascual R, Vardavas, Constantine, Varona Pérez, Patricia, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Verma, Madhur, Vetrova, Marina V, Vo, Bay, Vu, Giang Thu, Waheed, Yasir, Wang, Yanzhong, Welding, Kevin, Werdecker, Andrea, Whisnant, Joanna L, Wickramasinghe, Nuwan Darshana, Yamagishi, Kazumasa, Yandrapalli, Srikanth, Yatsuya, Hiroshi, Yazdi-Feyzabadi, Vahid, Yeshaw, Yigizie, Yimmer, Mohammed Zewdu, Yonemoto, Naohiro, Yu, Chuanhua, Yunusa, Ismaeel, Yusefzadeh, Hasan, Zahirian Moghadam, Telma, Zaman, Muhammed Shahriar, Zamanian, Maryam, Zandian, Hamed, Zar, Heather J, Zastrozhin, Mikhail Sergeevich, Zastrozhina, Anasthasia, Zavala-Arciniega, Lui, Zhang, Jianrong, Zhang, Zhi-Jiang, Zhong, Chenwen, Zuniga, Yves Miel H, Gakidou, Emmanuela, Collaborators, GBD 2019 Tobacco, Lacey, B, Lee Kong Chian School of Medicine (LKCMedicine), Department of Public Health, Clinicum, Neurologian yksikkö, HUS Neurocenter, University of Helsinki, HUS Comprehensive Cancer Center, GBD 2019 Tobacco Collaborators, Reitsma, M, Kendrick, P, Ababneh, E, Abbafati, C, Abbasi-Kangevari, M, Abdoli, A, Abedi, A, Abhilash, E, Abila, D, Aboyans, V, Abu-Rmeileh, N, Adebayo, O, Advani, S, Aghaali, M, Ahinkorah, B, Ahmad, S, Ahmadi, K, Ahmed, H, Aji, B, Akunna, C, Al-Aly, Z, Alanzi, T, Alhabib, K, Ali, L, Alif, S, Alipour, V, Aljunid, S, Alla, F, Allebeck, P, Alvis-Guzman, N, Amin, T, Amini, S, Amu, H, Amul, G, Ancuceanu, R, Anderson, J, Ansari-Moghaddam, A, Antonio, C, Antony, B, Anvari, D, Arabloo, J, Arian, N, Arora, M, Asaad, M, Ausloos, M, Awan, A, Ayano, G, Aynalem, G, Azari, S, B, D, Badiye, A, Baig, A, Bakhshaei, M, Banach, M, Banik, P, Barker-Collo, S, Bärnighausen, T, Barqawi, H, Basu, S, Bayati, M, Bazargan-Hejazi, S, Behzadifar, M, Bekuma, T, Bennett, D, Bensenor, I, Berfield, K, Bhagavathula, A, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bibi, S, Bijani, A, Bintoro, B, Biondi, A, Birara, S, Braithwaite, D, Brenner, H, Brunoni, A, Burkart, K, Butt, Z, Caetano dos Santos, F, Cámera, L, Car, J, Cárdenas, R, Carreras, G, Carrero, J, Castaldelli-Maia, J, Cattaruzza, M, Chang, J, Chen, S, Chu, D, Chung, S, Cirillo, M, Costa, V, Couto, R, Dadras, O, Dai, X, Damasceno, A, Damiani, G, Dandona, L, Dandona, R, Daneshpajouhnejad, P, Darega Gela, J, Davletov, K, Derbew Molla, M, Dessie, G, Desta, A, Dharmaratne, S, Dianatinasab, M, Diaz, D, Do, H, Douiri, A, Duncan, B, Duraes, A, Eagan, A, Ebrahimi Kalan, M, Edvardsson, K, Elbarazi, I, El Tantawi, M, Esmaeilnejad, S, Fadhil, I, Faraon, E, Farinha, C, Farwati, M, Farzadfar, F, Fazlzadeh, M, Feigin, V, Feldman, R, Fernandez Prendes, C, Ferrara, P, Filip, I, Filippidis, F, Fischer, F, Flor, L, Foigt, N, Folayan, M, Foroutan, M, Gad, M, Gaidhane, A, Gallus, S, Geberemariyam, B, Ghafourifard, M, Ghajar, A, Ghashghaee, A, Giampaoli, S, Gill, P, Glozah, F, Gnedovskaya, E, Golechha, M, Gopalani, S, Gorini, G, Goudarzi, H, Goulart, A, Greaves, F, Guha, A, Guo, Y, Gupta, B, Gupta, R, Gupta, T, Gupta, V, Hafezi-Nejad, N, Haider, M, Hamadeh, R, Hankey, G, Hargono, A, Hartono, R, Hassankhani, H, Hay, S, Heidari, G, Herteliu, C, Hezam, K, Hird, T, Hole, M, Holla, R, Hosseinzadeh, M, Hostiuc, S, Househ, M, Hsiao, T, Huang, J, Iannucci, V, Ibitoye, S, Idrisov, B, Ilesanmi, O, Ilic, I, Ilic, M, Inbaraj, L, Irvani, S, Islam, J, Islam, R, Islam, S, Islami, F, Iso, H, Itumalla, R, Iwagami, M, Jaafari, J, Jain, V, Jakovljevic, M, Jang, S, Janjani, H, Jayaram, S, Jeemon, P, Jha, R, Jonas, J, Joo, T, Jürisson, M, Kabir, A, Kabir, Z, Kalankesh, L, Kanchan, T, Kandel, H, Kapoor, N, Karimi, S, Katikireddi, S, Kebede, H, Kelkay, B, Kennedy, R, Khoja, A, Khubchandani, J, Kim, G, Kim, Y, Kimokoti, R, Kivimäki, M, Kosen, S, Koulmane Laxminarayana, S, Koyanagi, A, Krishan, K, Kugbey, N, Kumar, G, Kumar, N, Kurmi, O, Kusuma, D, Lam, J, Landires, I, Lasrado, S, Lauriola, P, Lee, D, Lee, Y, Leung, J, Li, S, Lin, H, Linn, S, Liu, W, Lopez, A, Lopukhov, P, Lorkowski, S, Lugo, A, Majeed, A, Maleki, A, Malekzadeh, R, Malta, D, Mamun, A, Manjunatha, N, Mansouri, B, Mansournia, M, Martinez-Raga, J, Martini, S, Mathur, M, Medina-Solís, C, Mehata, S, Mendoza, W, Menezes, R, Meretoja, A, Meretoja, T, Miazgowski, B, Michalek, I, Miller, T, Mirrakhimov, E, Mirzaei, H, Mirzaei-Alavijeh, M, Misra, S, Moghadaszadeh, M, Mohammad, Y, Mohammadian-Hafshejani, A, Mohammed, S, Mokdad, A, Monasta, L, Moni, M, Moradi, G, Moradi-Lakeh, M, Moradzadeh, R, Morrison, S, Mossie, T, Mubarik, S, Mullany, E, Murray, C, Naghavi, M, Naghshtabrizi, B, Nair, S, Nalini, M, Nangia, V, Naqvi, A, Narasimha Swamy, S, Naveed, M, Nayak, S, Nayak, V, Nazari, J, Nduaguba, S, Neupane Kandel, S, Nguyen, C, Nguyen, H, Nguyen, S, Nguyen, T, Nixon, M, Nnaji, C, Norrving, B, Noubiap, J, Nowak, C, Ogbo, F, Oguntade, A, Oh, I, Olagunju, A, Oren, E, Otstavnov, N, Otstavnov, S, Owolabi, M, P A, M, Pakhale, S, Pakshir, K, Palladino, R, Pana, A, Panda-Jonas, S, Pandey, A, Parekh, U, Park, E, Pashazadeh Kan, F, Patton, G, Pawar, S, Pestell, R, Pinheiro, M, Piradov, M, Pirouzpanah, S, Pokhrel, K, Polibin, R, Prashant, A, Pribadi, D, Radfar, A, Rahimi-Movaghar, V, Rahman, A, Rahman, M, Rahmani, A, Rajai, N, Ram, P, Ranabhat, C, Rathi, P, Rawal, L, Renzaho, A, Reynales-Shigematsu, L, Rezapour, A, Riahi, S, Riaz, M, Roever, L, Ronfani, L, Roshandel, G, Roy, A, Roy, B, Sacco, S, Saddik, B, Sahebkar, A, Salehi, S, Salimzadeh, H, Samaei, M, Samy, A, Santos, I, Santric-Milicevic, M, Sarrafzadegan, N, Sathian, B, Sawhney, M, Saylan, M, Schaub, M, Schmidt, M, Schneider, I, Schutte, A, Schwendicke, F, Seidu, A, Senthil Kumar, N, Sepanlou, S, Seylani, A, Shafaat, O, Shah, S, Shaikh, M, Shalash, A, Shannawaz, M, Sharafi, K, Sheikh, A, Sheikhbahaei, S, Shigematsu, M, Shiri, R, Shishani, K, Shivakumar, K, Shivalli, S, Shrestha, R, Siabani, S, Sidemo, N, Sigfusdottir, I, Sigurvinsdottir, R, Silva, D, Silva, J, Singh, A, Singh, J, Singh, V, Sinha, D, Sitas, F, Skryabin, V, Skryabina, A, Soboka, M, Soriano, J, Soroush, A, Soshnikov, S, Soyiri, I, Spurlock, E, Sreeramareddy, C, Stein, D, Steiropoulos, P, Stortecky, S, Straif, K, Suliankatchi Abdulkader, R, Sulo, G, Sundström, J, Tabuchi, T, Tadakamadla, S, Taddele, B, Tadesse, E, Tamiru, A, Tareke, M, Tareque, M, Tarigan, I, Temsah, M, Thankappan, K, Thapar, R, Tichopad, A, Tolani, M, Topouzis, F, Tovani-Palone, M, Tran, B, Tripathy, J, Tsegaye, G, Tsilimparis, N, Tymeson, H, Ullah, A, Ullah, S, Unim, B, Updike, R, Vacante, M, Valdez, P, Vardavas, C, Varona Pérez, P, Vasankari, T, Venketasubramanian, N, Verma, M, Vetrova, M, Vo, B, Vu, G, Waheed, Y, Wang, Y, Welding, K, Werdecker, A, Whisnant, J, Wickramasinghe, N, Yamagishi, K, Yandrapalli, S, Yatsuya, H, Yazdi-Feyzabadi, V, Yeshaw, Y, Yimmer, M, Yonemoto, N, Yu, C, Yunusa, I, Yusefzadeh, H, Zahirian Moghadam, T, Zaman, M, Zamanian, M, Zandian, H, Zar, H, Zastrozhin, M, Zastrozhina, A, Zavala-Arciniega, L, Zhang, J, Zhang, Z, Zhong, C, Zuniga, Y, and Gakidou, E
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030204 cardiovascular system & hematology ,0302 clinical medicine ,HV ,GBD 2019 Tobacco Collaborators ,Prevalence ,Global health ,Medicine ,030212 general & internal medicine ,610 Medicine & health ,11 Medical and Health Sciences ,RISK ,Tobacco control ,1. No poverty ,Public Health, Global Health, Social Medicine and Epidemiology ,General Medicine ,Articles ,Tobacco smoking ,3142 Public health care science, environmental and occupational health ,3. Good health ,A990 Medicine and Dentistry not elsewhere classified ,Life Sciences & Biomedicine ,HAZARDS ,03 medical and health sciences ,Medicine, General & Internal ,Environmental health ,General & Internal Medicine ,Tobacco ,Premature Deaths ,Population growth ,Medicine [Science] ,Global Burden ,Attributable Diseases ,Risk factor ,Mortality ,PROGRESS ,Disease burden ,Estimation ,Science & Technology ,business.industry ,Smoking Tobacco ,MORTALITY ,Former Smoker ,GOAL ,REDUCTION ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,3121 General medicine, internal medicine and other clinical medicine ,PREMATURE DEATHS ,business ,RA ,RC - Abstract
Background Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally. Methods We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We modelled multiple smoking-related indicators from 3625 nationally representative surveys. We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health outcomes to estimate non-linear dose-response risk curves for current and former smokers. We used a direct estimation approach to estimate attributable burden, providing more comprehensive estimates of the health effects of smoking than previously available. Findings Globally in 2019, 1·14 billion (95% uncertainty interval 1·13–1·16) individuals were current smokers, who consumed 7·41 trillion (7·11–7·74) cigarette-equivalents of tobacco in 2019. Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. Globally in 2019, smoking tobacco use accounted for 7·69 million (7·16–8·20) deaths and 200 million (185–214) disability-adjusted life-years, and was the leading risk factor for death among males (20·2% [19·3–21·1] of male deaths). 6·68 million [86·9%] of 7·69 million deaths attributable to smoking tobacco use were among current smokers. Interpretation In the absence of intervention, the annual toll of 7·69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. Substantial progress in reducing the prevalence of smoking tobacco use has been observed in countries from all regions and at all stages of development, but a large implementation gap remains for tobacco control. Countries have a clear and urgent opportunity to pass strong, evidence-based policies to accelerate reductions in the prevalence of smoking and reap massive health benefits for their citizens. Funding Bloomberg Philanthropies and the Bill & Melinda Gates Foundation.
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- 2021
15. Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: Update From the GBD 2019 Study
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Roth, Gregory A, Mensah, George A, Johnson, Catherine O, Addolorato, Giovanni, Ammirati, Enrico, Baddour, Larry M, Barengo, Noël C, Beaton, Andrea Z, Benjamin, Emelia J, Benziger, Catherine P, Bonny, Aimé, Brauer, Michael, Brodmann, Marianne, Cahill, Thomas J, Carapetis, Jonathan, Catapano, Alberico L, Chugh, Sumeet S, Cooper, Leslie T, Coresh, Josef, Criqui, Michael, DeCleene, Nicole, Eagle, Kim A, Emmons-Bell, Sophia, Feigin, Valery L, Fernández-Solà, Joaquim, Fowkes, Gerry, Gakidou, Emmanuela, Grundy, Scott M, He, Feng J, Howard, George, Hu, Frank, Inker, Lesley, Karthikeyan, Ganesan, Kassebaum, Nicholas, Koroshetz, Walter, Lavie, Carl, Lloyd-Jones, Donald, Lu, Hong S, Mirijello, Antonio, Temesgen, Awoke Misganaw, Mokdad, Ali, Moran, Andrew E, Muntner, Paul, Narula, Jagat, Neal, Bruce, Ntsekhe, Mpiko, Moraes de Oliveira, Glaucia, Otto, Catherine, Owolabi, Mayowa, Pratt, Michael, Rajagopalan, Sanjay, Reitsma, Marissa, Ribeiro, Antonio Luiz P, Rigotti, Nancy, Rodgers, Anthony, Sable, Craig, Shakil, Saate, Sliwa-Hahnle, Karen, Stark, Benjamin, Sundström, Johan, Timpel, Patrick, Tleyjeh, Imad M, Valgimigli, Marco, Vos, Theo, Whelton, Paul K, Yacoub, Magdi, Zuhlke, Liesl, Murray, Christopher, Fuster, Valentin, GBD-NHLBI-JACC Global, Burden of, Cardiovascular Diseases, Writing Group, Gregory A, Roth George, A Mensah, Catherine O, Johnson, Giovanni, Addolorato, Enrico, Ammirati, Larry M, Baddour Noel, C Barengo, Andrea, Beaton, Emelia J, Benjamin Catherine, P Benziger, Aime, Bonny, Michael, Brauer, Marianne, Brodmann, Thomas J, Cahill Jonathan, R Carapetis, Alberico L, Catapano, Sumeet, Chugh, Leslie T, Cooper, Josef, Coresh, Michael H, Criqui Nicole, K DeCleene, Kim A, Eagle, Sophia, Emmons-Bell, Valery L, Feigin, Joaquim, Fernández-Sola, F Gerry, R Fowkes, Emmanuela, Gakidou, Scott M, Grundy Feng, J He, George, Howard, Frank, Hu, Lesley, Inker, Ganesan, Karthikeyan, Nicholas J, Kassebaum Walter, J Koroshetz, Carl, Lavie, Donald, Lloyd-Jones, Hong S, Antonio, Mirijello, Awoke T, Misganaw Ali, H Mokdad, Andrew E, Moran, Paul, Muntner, Jagat, Narula, Bruce, Neal, Mpiko, Ntsekhe, Gláucia M, M Oliveira, Catherine M, Otto Mayowa, O Owolabi, Michael, Pratt, Sanjay, Rajagopalan, Marissa B, Reitsma Antonio, Luiz P, Ribeiro Nancy, A Rigotti, Anthony, Rodgers, Craig A, Sable Saate, S Shakil, Karen, Sliwa, Benjamin A, Stark, Johan, Sundström, Patrick, Timpel, Imad I, Tleyjeh, Marco, Valgimigli, Theo, Vos, Paul K, Whelton, Magdi, Yacoub, Liesl J, Zuhlke, Mohsen, Abbasi-Kangevari, Alireza, Abdi, Aidin, Abedi, Victor, Aboyans, Woldu A, Abrha, Eman, Abu-Gharbieh, Abdelrahman I, Abushouk, Dilaram, Acharya, Tim, Adair, Oladimeji M, Adebayo, Zanfina, Ademi, Shailesh M, Advani, Khashayar, Afshari, Ashkan, Afshin, Gina, Agarwal, Pradyumna, Agasthi, Sohail, Ahmad, Sepideh, Ahmadi, Muktar B, Ahmed, Budi, Aji, Yonas, Akalu, Wuraola, Akande-Sholabi, Addis, Aklilu, Chisom J, Akunna, Fares, Alahdab, Ayman, Al-Eyadhy, Khalid F, Alhabib Sheikh, M Alif, Vahid, Alipour, Syed M, Aljunid, François, Alla, Amir, Almasi-Hashiani, Sami, Almustanyir, Rajaa M, Al-Raddadi Adeladza, K Amegah, Saeed, Amini, Arya, Aminorroaya, Hubert, Amu, Dickson A, Amugsi, Robert, Ancuceanu, Deanna, Anderlini, Tudorel, Andrei, Catalina Liliana, Andrei, Alireza, Ansari-Moghaddam, Zelalem A, Anteneh Ippazio, Cosimo Antonazzo, Benny, Antony, Razique, Anwer, Lambert T, Appiah, Jalal, Arabloo, Johan, Ärnlöv, Kurnia D, Artanti, Zerihun, Ataro, Marcel, Ausloos, Leticia, Avila-Burgos, Asma T, Awan Mamaru, A Awoke, Henok T, Ayele Muluken, A Ayza, Samad, Azari, Darshan B, B, Nafiseh, Baheiraei, Atif A, Baig, Ahad, Bakhtiari, Maciej, Banach, Palash C, Banik Emerson, A Baptista, Miguel A, Barboza, Lingkan, Barua, Sanjay, Basu, Neeraj, Bedi, Yannick, Béjot, Derrick A, Bennett Isabela, M Bensenor, Adam E, Berman Yihienew, M Bezabih, Akshaya S, Bhagavathula, Sonu, Bhaskar, Krittika, Bhattacharyya, Ali, Bijani, Boris, Bikbov, Mulugeta M, Birhanu, Archith, Boloor, Luisa C, Brant, Hermann, Brenner, Nikolay I, Briko Zahid, A Butt, Florentino Luciano, Caetano Dos, Santos Leah, E Cahill, Lucero, Cahuana-Hurtado, Luis A, Cámera Ismael, R Campos-Nonato, Carlos, Cantu-Brito, Josip, Car, Juan J, Carrero, Felix, Carvalho, Carlos A, Castañeda-Orjuela, Ferrán, Catalá-López, Ester, Cerin, Jaykaran, Charan, Vijay Kumar, Chattu, Simiao, Chen, Ken L, Chin Jee-Young, J Choi, Dinh-Toi, Chu, Sheng-Chia, Chung, Cirillo, Massimo, Sean, Coffey, Sara, Conti, Vera M, Costa David, K Cundiff, Omid, Dadras, Baye, Dagnew, Xiaochen, Dai, Albertino A, M Damasceno, Lalit, Dandona, Rakhi, Dandona, Kairat, Davletov, Vanessa De, la Cruz-Góngora, Fernando P, De la, Hoz Jan-Walter, De Neve, Edgar, Denova-Gutiérrez, Meseret Derbew, Molla Behailu, T Derseh, Rupak, Desai, Günther, Deuschl, Samath D, Dharmaratne, Meghnath, Dhimal, Raja Ram, Dhungana, Mostafa, Dianatinasab, Daniel, Diaz, Shirin, Djalalinia, Klara, Dokova, Abdel, Douiri, Bruce B, Duncan Andre, R Duraes, Arielle W, Eagan, Sanam, Ebtehaj, Aziz, Eftekhari, Sahar, Eftekharzadeh, Michael, Ekholuenetale, Nevine El, Nahas Islam, Y Elgendy, Muhammed, Elhadi, Shaimaa I, El-Jaafary, Sadaf, Esteghamati, Atkilt E, Etisso, Oghenowede, Eyawo, Ibtihal, Fadhil, Emerito Jose, A Faraon, Pawan S, Faris, Medhat, Farwati, Farshad, Farzadfar, Eduarda, Fernandes, Carlota Fernandez, Prendes, Pietro, Ferrara, Irina, Filip, Florian, Fischer, David, Flood, Takeshi, Fukumoto, Mohamed M, Gad, Shilpa, Gaidhane, Morsaleh, Ganji, Jalaj, Garg, Abadi K, Gebre Birhan, G Gebregiorgis, Kidane Z, Gebregzabiher Gebreamlak, G Gebremeskel, Lemma, Getacher, Abera Getachew, Obsa, Alireza, Ghajar, Ahmad, Ghashghaee, Nermin, Ghith, Simona, Giampaoli, Syed Amir, Gilani Paramjit, S Gill, Richard F, Gillum Ekaterina, V Glushkova, Elena V, Gnedovskaya, Mahaveer, Golechha, Kebebe B, Gonfa Amir, Hossein Goudarzian, Alessandra C, Goulart Jenny, S Guadamuz, Avirup, Guha, Yuming, Guo, Rajeev, Gupta, Vladimir, Hachinski, Nima, Hafezi-Nejad, Teklehaimanot G, Haile Randah, R Hamadeh, Samer, Hamidi, Graeme J, Hankey, Arief, Hargono, Risky K, Hartono, Maryam, Hashemian, Abdiwahab, Hashi, Shoaib, Hassan, Hamid Y, Hassen Rasmus, J Havmoeller, Simon I, Hay, Khezar, Hayat, Golnaz, Heidari, Claudiu, Herteliu, Ramesh, Holla, Mostafa, Hosseini, Mehdi, Hosseinzadeh, Mihaela, Hostiuc, Sorin, Hostiuc, Mowafa, Househ, Junjie, Huang, Ayesha, Humayun, Ivo, Iavicoli, Charles U, Ibeneme Segun, E Ibitoye, Olayinka S, Ilesanmi Irena, M Ilic, Milena D, Ilic, Usman, Iqbal, Seyed Sina, N Irvani, Sheikh Mohammed, Shariful Islam, Rakibul M, Islam, Hiroyasu, Iso, Masao, Iwagami, Vardhmaan, Jain, Tahereh, Javaheri, Sathish Kumar, Jayapal, Shubha, Jayaram, Ranil, Jayawardena, Panniyammakal, Jeemon, Ravi P, Jha Jost, B Jonas, Jitendra, Jonnagaddala, Farahnaz, Joukar, Jacek J, Jozwiak, Mikk, Jürisson, Ali, Kabir, Tanvir, Kahlon, Rizwan, Kalani, Rohollah, Kalhor, Ashwin, Kamath, Ibrahim, Kamel, Himal, Kandel, Amit, Kandel, André, Karch, Ayele Semachew, Kasa Patrick, D M, C Katoto, Gbenga A, Kayode Yousef, S Khader, Mohammad, Khammarnia, Muhammad S, Khan Md, Nuruzzaman Khan, Maseer, Khan, Ejaz A, Khan, Khaled, Khatab, Gulam M, A Kibria, Yun Jin, Kim Gyu, Ri Kim, Ruth W, Kimokoti, Sezer, Kisa, Adnan, Kisa, Mika, Kivimäki, Dhaval, Kolte, Ali, Koolivand, Vladimir A, Korshunov Sindhura, Lakshmi Koulmane, Laxminarayana, Ai, Koyanagi, Kewal, Krishan, Vijay, Krishnamoorthy, Barthelemy Kuate, Defo Burcu, Kucuk Bicer, Vaman, Kulkarni, G Anil, Kumar, Nithin, Kumar, Om P, Kurmi, Dian, Kusuma, Gene F, Kwan Carlo, La Vecchia, Ben, Lacey, Tea, Lallukka, Qing, Lan, Savita, Lasrado, Zohra S, Lassi, Paolo, Lauriola, Wayne R, Lawrence, Avula, Laxmaiah, Kate E, LeGrand, Ming-Chieh, Li, Bingyu, Li, Shanshan, Li, Stephen S, Lim, Lee-Ling, Lim, Hualiang, Lin, Ziqiang, Lin, Ro-Ting, Lin, Xuefeng, Liu, Alan D, Lopez, Stefan, Lorkowski, Paulo A, Lotufo, Alessandra, Lugo, Nirmal K, M, Fabiana, Madotto, Morteza, Mahmoudi, Azeem, Majeed, Reza, Malekzadeh, Ahmad A, Malik Abdullah, A Mamun, Navid, Manafi, Mohammad Ali, Mansournia Lorenzo, G Mantovani, Santi, Martini, Manu R, Mathur, Giampiero, Mazzaglia, Suresh, Mehata, Man Mohan, Mehndiratta, Toni, Meier, Ritesh G, Menezes, Atte, Meretoja, Tomislav, Mestrovic, Bartosz, Miazgowski, Tomasz, Miazgowski, Irmina Maria, Michalek Ted, R Miller, Erkin M, Mirrakhimov, Hamed, Mirzaei, Babak, Moazen, Masoud, Moghadaszadeh, Yousef, Mohammad, Dara K, Mohammad, Shafiu, Mohammed, Mohammed A, Mohammed, Yaser, Mokhayeri, Mariam, Molokhia, Ahmed A, Montasir, Ghobad, Moradi, Rahmatollah, Moradzadeh, Paula, Moraga, Lidia, Morawska, Ilais Moreno, Velásquez, Jakub, Morze, Sumaira, Mubarik, Walter, Muruet, Kamarul Imran, Musa Ahamarshan, J Nagarajan, Mahdi, Nalini, Vinay, Nangia, Atta Abbas, Naqvi Sreenivas, Narasimha Swamy, Bruno R, Nascimento Vinod, C Nayak, Javad, Nazari, Milad, Nazarzadeh, Ruxandra I, Negoi Sandhya, Neupane Kandel, Huong L, T Nguyen, Molly R, Nixon, Bo, Norrving, Jean Jacques, Noubiap Brice, E Nouthe, Christoph, Nowak, Oluwakemi O, Odukoya Felix, A Ogbo, Andrew T, Olagunju, Hans, Orru, Alberto, Ortiz, Samuel M, Ostroff Jagadish, Rao Padubidri, Raffaele, Palladino, Adrian, Pana, Songhomitra, Panda-Jonas, Utsav, Parekh, Eun-Cheol, Park, Mojtaba, Parvizi, Fatemeh Pashazadeh, Kan Urvish, K Patel, Mona, Pathak, Rajan, Paudel, Veincent Christian, F Pepito, Arokiasamy, Perianayagam, Norberto, Perico, Hai Q, Pham, Thomas, Pilgrim, Michael A, Piradov, Farhad, Pishgar, Vivek, Podder, Roman V, Polibin, Akram, Pourshams, Dimas R, A Pribadi, Navid, Rabiee, Mohammad, Rabiee, Amir, Radfar, Alireza, Rafiei, Fakher, Rahim, Vafa, Rahimi-Movaghar, Mohammad Hifz, Ur Rahman, Muhammad Aziz, Rahman Amir, Masoud Rahmani, Ivo, Rakovac, Pradhum, Ram, Sudha, Ramalingam, Juwel, Rana, Priyanga, Ranasinghe, Sowmya J, Rao, Priya, Rathi, Lal, Rawal, Wasiq F, Rawasia, Reza, Rawassizadeh, Giuseppe, Remuzzi, Andre M, N Renzaho, Aziz, Rezapour, Seyed Mohammad, Riahi Ross, L Roberts-Thomson, Leonardo, Roever, Peter, Rohloff, Michele, Romoli, Gholamreza, Roshandel, Godfrey M, Rwegerera, Seyedmohammad, Saadatagah, Maha M, Saber-Ayad, Siamak, Sabour, Simona, Sacco, Masoumeh, Sadeghi, Sahar Saeedi, Moghaddam, Saeed, Safari, Amirhossein, Sahebkar, Sana, Salehi, Hamideh, Salimzadeh, Mehrnoosh, Samaei, Abdallah M, Samy Itamar, S Santos, Milena M, Santric-Milicevic, Nizal, Sarrafzadegan, Arash, Sarveazad, Thirunavukkarasu, Sathish, Monika, Sawhney, Mete, Saylan, Maria I, Schmidt Aletta, E Schutte, Subramanian, Senthilkumaran, Sadaf G, Sepanlou, Feng, Sha, Saeed, Shahabi, Izza, Shahid, Masood A, Shaikh, Mahdi, Shamali, Morteza, Shamsizadeh, Md Shajedur, Rahman Shawon, Aziz, Sheikh, Mika, Shigematsu, Min-Jeong, Shin, Jae Il, Shin, Rahman, Shiri, Ivy, Shiue, Kerem, Shuval, Soraya, Siabani, Tariq J, Siddiqi Diego, A S, Silva Jasvinder, A Singh, Ambrish Singh, Mtech Valentin, Y Skryabin, Anna A, Skryabina, Amin, Soheili, Emma E, Spurlock, Leo, Stockfelt, Stefan, Stortecky, Saverio, Stranges, Rizwan Suliankatchi, Abdulkader, Hooman, Tadbiri, Eyayou G, Tadesse Degena, B Tadesse, Masih, Tajdini, Md, Tariqujjaman, Berhane F, Teklehaimanot, Mohamad-Hani, Temsah, Ayenew K, Tesema, Bhaskar, Thakur, Kavumpurathu R, Thankappan, Rekha, Thapar, Amanda G, Thrift, Binod, Timalsina, Marcello, Tonelli, Mathilde, Touvier, Marcos R, Tovani-Palone, Avnish, Tripathi, Jaya P, Tripathy Thomas, C Truelsen, Guesh M, Tsegay Gebiyaw, W Tsegaye, Nikolaos, Tsilimparis, Biruk S, Tusa, Stefanos, Tyrovolas, Krishna Kishore, Umapathi, Brigid, Unim, Bhaskaran, Unnikrishnan, Usman, Muthiah, Vaduganathan, Pascual R, Valdez Tommi, J Vasankari, Diana Z, Velazquez, Narayanaswamy, Venketasubramanian, Giang T, Vu Isidora, S Vujcic, Yasir, Waheed, Yanzhong, Wang, Fang, Wang, Jingkai, Wei, Robert G, Weintraub Abrha, H Weldemariam, Ronny, Westerman, Andrea S, Winkler Charles, S Wiysonge, Charles D, A Wolfe, Befikadu Legesse, Wubishet, Gelin, Xu, Ali, Yadollahpour, Kazumasa, Yamagishi, Lijing L, Yan, Srikanth, Yandrapalli, Yuichiro, Yano, Hiroshi, Yatsuya, Tomas Y, Yeheyis, Yigizie, Yeshaw, Christopher S, Yilgwan, Naohiro, Yonemoto, Chuanhua, Yu, Hasan, Yusefzadeh, Geevar, Zachariah, Sojib Bin, Zaman Muhammed, S Zaman, Maryam, Zamanian, Ramin, Zand, Alireza, Zandifar, Afshin, Zarghi, Mikhail S, Zastrozhin, Anasthasia, Zastrozhina, Zhi-Jiang, Zhang, Yunquan, Zhang, Wangjian, Zhang, Chenwen, Zhong, Zhiyong, Zou, Yves Miel, H Zuniga, Christopher J, L Murray, Valentin, Fuster, Roth, G, Mensah, G, Johnson, C, Addolorato, G, Ammirati, E, Baddour, L, Barengo, N, Beaton, A, Benjamin, E, Benziger, C, Bonny, A, Brauer, M, Brodmann, M, Cahill, T, Carapetis, J, Catapano, A, Chugh, S, Cooper, L, Coresh, J, Criqui, M, Decleene, N, Eagle, K, Emmons-Bell, S, Feigin, V, Fernandez-Sola, J, Fowkes, G, Gakidou, E, Grundy, S, He, F, Howard, G, Hu, F, Inker, L, Karthikeyan, G, Kassebaum, N, Koroshetz, W, Lavie, C, Lloyd-Jones, D, Lu, H, Mirijello, A, Temesgen, A, Mokdad, A, Moran, A, Muntner, P, Narula, J, Neal, B, Ntsekhe, M, Moraes de Oliveira, G, Otto, C, Owolabi, M, Pratt, M, Rajagopalan, S, Reitsma, M, Ribeiro, A, Rigotti, N, Rodgers, A, Sable, C, Shakil, S, Sliwa-Hahnle, K, Stark, B, Sundstrom, J, Timpel, P, Tleyjeh, I, Valgimigli, M, Vos, T, Whelton, P, Yacoub, M, Zuhlke, L, Murray, C, Fuster, V, Fowkes, F, Misganaw, A, Oliveira, G, Sliwa, K, Abbasi-Kangevari, M, Abdi, A, Abedi, A, Aboyans, V, Abrha, W, Abu-Gharbieh, E, Abushouk, A, Acharya, D, Adair, T, Adebayo, O, Ademi, Z, Advani, S, Afshari, K, Afshin, A, Agarwal, G, Agasthi, P, Ahmad, S, Ahmadi, S, Ahmed, M, Aji, B, Akalu, Y, Akande-Sholabi, W, Aklilu, A, Akunna, C, Alahdab, F, Al-Eyadhy, A, Alhabib, K, Alif, S, Alipour, V, Aljunid, S, Alla, F, Almasi-Hashiani, A, Almustanyir, S, Al-Raddadi, R, Amegah, A, Amini, S, Aminorroaya, A, Amu, H, Amugsi, D, Ancuceanu, R, Anderlini, D, Andrei, T, Andrei, C, Ansari-Moghaddam, A, Anteneh, Z, Antonazzo, I, Antony, B, Anwer, R, Appiah, L, Arabloo, J, Arnlov, J, Artanti, K, Ataro, Z, Ausloos, M, Avila-Burgos, L, Awan, A, Awoke, M, Ayele, H, Ayza, M, Azari, S, B, D, Baheiraei, N, Baig, A, Bakhtiari, A, Banach, M, Banik, P, Baptista, E, Barboza, M, Barua, L, Basu, S, Bedi, N, Bejot, Y, Bennett, D, Bensenor, I, Berman, A, Bezabih, Y, Bhagavathula, A, Bhaskar, S, Bhattacharyya, K, Bijani, A, Bikbov, B, Birhanu, M, Boloor, A, Brant, L, Brenner, H, Briko, N, Butt, Z, Caetano dos Santos, F, Cahill, L, Cahuana-Hurtado, L, Camera, L, Campos-Nonato, I, Cantu-Brito, C, Car, J, Carrero, J, Carvalho, F, Castaneda-Orjuela, C, Catala-Lopez, F, Cerin, E, Charan, J, Chattu, V, Chen, S, Chin, K, Choi, J, Chu, D, Chung, S, Cirillo, M, Coffey, S, Conti, S, Costa, V, Cundiff, D, Dadras, O, Dagnew, B, Dai, X, Damasceno, A, Dandona, L, Dandona, R, Davletov, K, De la Cruz-Gongora, V, De la Hoz, F, De Neve, J, Denova-Gutierrez, E, Derbew Molla, M, Derseh, B, Desai, R, Deuschl, G, Dharmaratne, S, Dhimal, M, Dhungana, R, Dianatinasab, M, Diaz, D, Djalalinia, S, Dokova, K, Douiri, A, Duncan, B, Duraes, A, Eagan, A, Ebtehaj, S, Eftekhari, A, Eftekharzadeh, S, Ekholuenetale, M, El Nahas, N, Elgendy, I, Elhadi, M, El-Jaafary, S, Esteghamati, S, Etisso, A, Eyawo, O, Fadhil, I, Faraon, E, Faris, P, Farwati, M, Farzadfar, F, Fernandes, E, Fernandez Prendes, C, Ferrara, P, Filip, I, Fischer, F, Flood, D, Fukumoto, T, Gad, M, Gaidhane, S, Ganji, M, Garg, J, Gebre, A, Gebregiorgis, B, Gebregzabiher, K, Gebremeskel, G, Getacher, L, Obsa, A, Ghajar, A, Ghashghaee, A, Ghith, N, Giampaoli, S, Gilani, S, Gill, P, Gillum, R, Glushkova, E, Gnedovskaya, E, Golechha, M, Gonfa, K, Goudarzian, A, Goulart, A, Guadamuz, J, Guha, A, Guo, Y, Gupta, R, Hachinski, V, Hafezi-Nejad, N, Haile, T, Hamadeh, R, Hamidi, S, Hankey, G, Hargono, A, Hartono, R, Hashemian, M, Hashi, A, Hassan, S, Hassen, H, Havmoeller, R, Hay, S, Hayat, K, Heidari, G, Herteliu, C, Holla, R, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Huang, J, Humayun, A, Iavicoli, I, Ibeneme, C, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Iqbal, U, Irvani, S, Islam, S, Islam, R, Iso, H, Iwagami, M, Jain, V, Javaheri, T, Jayapal, S, Jayaram, S, Jayawardena, R, Jeemon, P, Jha, R, Jonas, J, Jonnagaddala, J, Joukar, F, Jozwiak, J, Jurisson, M, Kabir, A, Kahlon, T, Kalani, R, Kalhor, R, Kamath, A, Kamel, I, Kandel, H, Kandel, A, Karch, A, Kasa, A, Katoto, P, Kayode, G, Khader, Y, Khammarnia, M, Khan, M, Khan, E, Khatab, K, Kibria, G, Kim, Y, Kim, G, Kimokoti, R, Kisa, S, Kisa, A, Kivimaki, M, Kolte, D, Koolivand, A, Korshunov, V, Koulmane Laxminarayana, S, Koyanagi, A, Krishan, K, Krishnamoorthy, V, Kuate Defo, B, Kucuk Bicer, B, Kulkarni, V, Kumar, G, Kumar, N, Kurmi, O, Kusuma, D, Kwan, G, La Vecchia, C, Lacey, B, Lallukka, T, Lan, Q, Lasrado, S, Lassi, Z, Lauriola, P, Lawrence, W, Laxmaiah, A, Legrand, K, Li, M, Li, B, Li, S, Lim, S, Lim, L, Lin, H, Lin, Z, Lin, R, Liu, X, Lopez, A, Lorkowski, S, Lotufo, P, Lugo, A, M, N, Madotto, F, Mahmoudi, M, Majeed, A, Malekzadeh, R, Malik, A, Mamun, A, Manafi, N, Mansournia, M, Mantovani, L, Martini, S, Mathur, M, Mazzaglia, G, Mehata, S, Mehndiratta, M, Meier, T, Menezes, R, Meretoja, A, Mestrovic, T, Miazgowski, B, Miazgowski, T, Michalek, I, Miller, T, Mirrakhimov, E, Mirzaei, H, Moazen, B, Moghadaszadeh, M, Mohammad, Y, Mohammad, D, Mohammed, S, Mohammed, M, Mokhayeri, Y, Molokhia, M, Montasir, A, Moradi, G, Moradzadeh, R, Moraga, P, Morawska, L, Moreno Velasquez, I, Morze, J, Mubarik, S, Muruet, W, Musa, K, Nagarajan, A, Nalini, M, Nangia, V, Naqvi, A, Narasimha Swamy, S, Nascimento, B, Nayak, V, Nazari, J, Nazarzadeh, M, Negoi, R, Neupane Kandel, S, Nguyen, H, Nixon, M, Norrving, B, Noubiap, J, Nouthe, B, Nowak, C, Odukoya, O, Ogbo, F, Olagunju, A, Orru, H, Ortiz, A, Ostroff, S, Padubidri, J, Palladino, R, Pana, A, Panda-Jonas, S, Parekh, U, Park, E, Parvizi, M, Pashazadeh Kan, F, Patel, U, Pathak, M, Paudel, R, Pepito, V, Perianayagam, A, Perico, N, Pham, H, Pilgrim, T, Piradov, M, Pishgar, F, Podder, V, Polibin, R, Pourshams, A, Pribadi, D, Rabiee, N, Rabiee, M, Radfar, A, Rafiei, A, Rahim, F, Rahimi-Movaghar, V, Ur Rahman, M, Rahman, M, Rahmani, A, Rakovac, I, Ram, P, Ramalingam, S, Rana, J, Ranasinghe, P, Rao, S, Rathi, P, Rawal, L, Rawasia, W, Rawassizadeh, R, Remuzzi, G, Renzaho, A, Rezapour, A, Riahi, S, Roberts-Thomson, R, Roever, L, Rohloff, P, Romoli, M, Roshandel, G, Rwegerera, G, Saadatagah, S, Saber-Ayad, M, Sabour, S, Sacco, S, Sadeghi, M, Saeedi Moghaddam, S, Safari, S, Sahebkar, A, Salehi, S, Salimzadeh, H, Samaei, M, Samy, A, Santos, I, Santric-Milicevic, M, Sarrafzadegan, N, Sarveazad, A, Sathish, T, Sawhney, M, Saylan, M, Schmidt, M, Schutte, A, Senthilkumaran, S, Sepanlou, S, Sha, F, Shahabi, S, Shahid, I, Shaikh, M, Shamali, M, Shamsizadeh, M, Shawon, M, Sheikh, A, Shigematsu, M, Shin, M, Shin, J, Shiri, R, Shiue, I, Shuval, K, Siabani, S, Siddiqi, T, Silva, D, Singh, J, Mtech, A, Skryabin, V, Skryabina, A, Soheili, A, Spurlock, E, Stockfelt, L, Stortecky, S, Stranges, S, Suliankatchi Abdulkader, R, Tadbiri, H, Tadesse, E, Tadesse, D, Tajdini, M, Tariqujjaman, M, Teklehaimanot, B, Temsah, M, Tesema, A, Thakur, B, Thankappan, K, Thapar, R, Thrift, A, Timalsina, B, Tonelli, M, Touvier, M, Tovani-Palone, M, Tripathi, A, Tripathy, J, Truelsen, T, Tsegay, G, Tsegaye, G, Tsilimparis, N, Tusa, B, Tyrovolas, S, Umapathi, K, Unim, B, Unnikrishnan, B, Usman, M, Vaduganathan, M, Valdez, P, Vasankari, T, Velazquez, D, Venketasubramanian, N, Vu, G, Vujcic, I, Waheed, Y, Wang, Y, Wang, F, Wei, J, Weintraub, R, Weldemariam, A, Westerman, R, Winkler, A, Wiysonge, C, Wolfe, C, Wubishet, B, Xu, G, Yadollahpour, A, Yamagishi, K, Yan, L, Yandrapalli, S, Yano, Y, Yatsuya, H, Yeheyis, T, Yeshaw, Y, Yilgwan, C, Yonemoto, N, Yu, C, Yusefzadeh, H, Zachariah, G, Zaman, S, Zaman, M, Zamanian, M, Zand, R, Zandifar, A, Zarghi, A, Zastrozhin, M, Zastrozhina, A, Zhang, Z, Zhang, Y, Zhang, W, Zhong, C, Zou, Z, Zuniga, Y, Roth, Gregory A, Mensah, George A, Johnson, Catherine O, Addolorato, Giovanni, Ammirati, Enrico, Baddour, Larry M, Barengo, Noël C, Beaton, Andrea Z, Benjamin, Emelia J, Benziger, Catherine P, Bonny, Aimé, Brauer, Michael, Brodmann, Marianne, Cahill, Thomas J, Carapetis, Jonathan, Catapano, Alberico L, Chugh, Sumeet S, Cooper, Leslie T, Coresh, Josef, Criqui, Michael, Decleene, Nicole, Eagle, Kim A, Emmons-Bell, Sophia, Feigin, Valery L, Fernández-Solà, Joaquim, Fowkes, Gerry, Gakidou, Emmanuela, Grundy, Scott M, Feng J, He, Howard, George, Frank, Hu, Inker, Lesley, Karthikeyan, Ganesan, Kassebaum, Nichola, Koroshetz, Walter, Lavie, Carl, Lloyd-Jones, Donald, Hong S, Lu, Mirijello, Antonio, Temesgen, Awoke Misganaw, Mokdad, Ali, Moran, Andrew E, Muntner, Paul, Narula, Jagat, Neal, Bruce, Ntsekhe, Mpiko, Moraes de Oliveira, Glaucia, Otto, Catherine, Owolabi, Mayowa, Pratt, Michael, Rajagopalan, Sanjay, Reitsma, Marissa, Ribeiro, Antonio Luiz P, Rigotti, Nancy, Rodgers, Anthony, Sable, Craig, Shakil, Saate, Sliwa-Hahnle, Karen, Stark, Benjamin, Sundström, Johan, Timpel, Patrick, Tleyjeh, Imad M, Valgimigli, Marco, Vos, Theo, Whelton, Paul K, Yacoub, Magdi, Zuhlke, Liesl, Murray, Christopher, Fuster, Valentin, GBD-NHLBI-JACC, Global, Burden, Of, Cardiovascular, Disease, Writing, Group, Gregory, A, Roth, George, Mensah, A, Catherine, O, Johnson, Giovanni, Addolorato, Enrico, Ammirati, Larry, M, Baddour, Noel, Barengo, C, Andrea, Beaton, Emelia, J, Benjamin, Catherine, Benziger, P, Aime, Bonny, Michael, Brauer, Marianne, Brodmann, Thomas, J, Cahill, Jonathan, Carapetis, R, Alberico, L, Catapano, Sumeet, Chugh, Leslie, T, Cooper, Josef, Coresh, Michael, H, Criqui, Nicole, Decleene, K, Kim, A, Eagle, Sophia, Emmons-Bell, Valery, L, Feigin, Joaquim, Fernández-Sola, Gerry, F, Fowkes, R, Emmanuela, Gakidou, Scott, M, Grundy, Feng, J, He, George, Howard, Lesley, Inker, Ganesan, Karthikeyan, Nicholas, J, Kassebaum, Walter, Koroshetz, J, Carl, Lavie, Donald, Lloyd-Jone, Hong, S, Lu, Antonio, Mirijello, Awoke, T, Misganaw, Ali, Mokdad, H, Andrew, E, Moran, Paul, Muntner, Jagat, Narula, Bruce, Neal, Mpiko, Ntsekhe, Gláucia, M, Oliveira, M, Catherine, M, Otto, Mayowa, Owolabi, O, Michael, Pratt, Sanjay, Rajagopalan, Marissa, B, Reitsma, Antonio, Luiz, P, Ribeiro, Nancy, Rigotti, A, Anthony, Rodger, Craig, A, Sable, Saate, Karen, Sliwa, Benjamin, A, Stark, Johan, Sundström, Patrick, Timpel, Imad, I, Tleyjeh, Marco, Valgimigli, Theo, Vo, Paul, K, Whelton, Magdi, Yacoub, Liesl, J, Zuhlke, Mohsen, Abbasi-Kangevari, Alireza, Abdi, Aidin, Abedi, Victor, Aboyan, Woldu, A, Abrha, Eman, Abu-Gharbieh, Abdelrahman, I, Abushouk, Dilaram, Acharya, Tim, Adair, Oladimeji, M, Adebayo, Zanfina, Ademi, Shailesh, M, Advani, Khashayar, Afshari, Ashkan, Afshin, Gina, Agarwal, Pradyumna, Agasthi, Sohail, Ahmad, Sepideh, Ahmadi, Muktar, B, Ahmed, Budi, Aji, Yonas, Akalu, Wuraola, Akande-Sholabi, Addis, Aklilu, Chisom, J, Akunna, Fares, Alahdab, Ayman, Al-Eyadhy, Khalid, F, Alhabib, Sheikh, Alif, M, Vahid, Alipour, Syed, M, Aljunid, François, Alla, Amir, Almasi-Hashiani, Sami, Almustanyir, Rajaa, M, Al-Raddadi, Adeladza, Amegah, K, Saeed, Amini, Arya, Aminorroaya, Hubert, Amu, Dickson, A, Amugsi, Robert, Ancuceanu, Deanna, Anderlini, Tudorel, Andrei, Catalina, Liliana, Andrei, Alireza, Ansari-Moghaddam, Zelalem, A, Anteneh, Ippazio, Cosimo, Antonazzo, Benny, Antony, Razique, Anwer, Lambert, T, Appiah, Jalal, Arabloo, Johan, Ärnlöv, Kurnia, D, Artanti, Zerihun, Ataro, Marcel, Ausloo, Leticia, Avila-Burgo, Asma, T, Awan, Mamaru, Awoke, A, Henok, T, Ayele, Muluken, Ayza, A, Samad, Azari, Darshan, B, B, Nafiseh, Baheiraei, Atif, A, Baig, Ahad, Bakhtiari, Maciej, Banach, Palash, C, Banik, Emerson, Baptista, A, Miguel, A, Barboza, Lingkan, Barua, Sanjay, Basu, Neeraj, Bedi, Yannick, Béjot, Derrick, A, Bennett, Isabela, Bensenor, M, Adam, E, Berman, Yihienew, Bezabih, M, Akshaya, S, Bhagavathula, Sonu, Bhaskar, Krittika, Bhattacharyya, Ali, Bijani, Boris, Bikbov, Mulugeta, M, Birhanu, Archith, Boloor, Luisa, C, Brant, Hermann, Brenner, Nikolay, I, Briko, Zahid, Butt, A, Florentino, Luciano, Caetano, Do, Santos, Leah, Cahill, E, Lucero, Cahuana-Hurtado, Luis, A, Cámera, Ismael, Campos-Nonato, R, Carlos, Cantu-Brito, Josip, Car, Juan, J, Carrero, Felix, Carvalho, Carlos, A, Castañeda-Orjuela, Ferrán, Catalá-López, Ester, Cerin, Jaykaran, Charan, Vijay, Kumar, Chattu, Simiao, Chen, Ken, L, Chin, Jee-Young, Dinh-Toi, Chu, Sheng-Chia, Chung, Cirillo, Massimo, Sean, Coffey, Sara, Conti, Vera, M, Costa, David, Cundiff, K, Omid, Dadra, Baye, Dagnew, Xiaochen, Dai, Albertino, A, Damasceno, M, Lalit, Dandona, Rakhi, Dandona, Kairat, Davletov, Vanessa, De, Cruz-Góngora, La, Fernando, P, De, La, Hoz, Jan-Walter, Neve, De, Edgar, Denova-Gutiérrez, Meseret, Derbew, Molla, Behailu, Derseh, T, Rupak, Desai, Günther, Deuschl, Samath, D, Dharmaratne, Meghnath, Dhimal, Raja, Ram, Dhungana, Mostafa, Dianatinasab, Daniel, Diaz, Shirin, Djalalinia, Klara, Dokova, Abdel, Douiri, Bruce, B, Duncan, Andre, Duraes, R, Arielle, W, Eagan, Sanam, Ebtehaj, Aziz, Eftekhari, Sahar, Eftekharzadeh, Michael, Ekholuenetale, Nevine, El, Nahas, Islam, Elgendy, Y, Muhammed, Elhadi, Shaimaa, I, El-Jaafary, Sadaf, Esteghamati, Atkilt, E, Etisso, Oghenowede, Eyawo, Ibtihal, Fadhil, Emerito, Jose, Faraon, A, Pawan, S, Faris, Medhat, Farwati, Farshad, Farzadfar, Eduarda, Fernande, Carlota, Fernandez, Prendes, Pietro, Ferrara, Irina, Filip, Florian, Fischer, David, Flood, Takeshi, Fukumoto, Mohamed, M, Gad, Shilpa, Gaidhane, Morsaleh, Ganji, Jalaj, Garg, Abadi, K, Gebre, Birhan, Gebregiorgis, G, Kidane, Z, Gebregzabiher, Gebreamlak, Lemma, Getacher, Abera, Getachew, Obsa, Alireza, Ghajar, Ahmad, Ghashghaee, Nermin, Ghith, Simona, Giampaoli, Syed, Amir, Gilani, Paramjit, Gill, S, Richard, F, Gillum, Ekaterina, Glushkova, V, Elena, V, Gnedovskaya, Mahaveer, Golechha, Kebebe, B, Gonfa, Amir, Hossein, Goudarzian, Alessandra, C, Goulart, Jenny, Guadamuz, S, Avirup, Guha, Yuming, Guo, Rajeev, Gupta, Vladimir, Hachinski, Nima, Hafezi-Nejad, Teklehaimanot, G, Haile, Randah, Samer, Hamidi, Graeme, J, Hankey, Arief, Hargono, Risky, K, Hartono, Maryam, Hashemian, Abdiwahab, Hashi, Shoaib, Hassan, Hamid, Y, Hassen, Rasmu, Havmoeller, J, Simon, I, Hay, Khezar, Hayat, Golnaz, Heidari, Claudiu, Herteliu, Ramesh, Holla, Mostafa, Hosseini, Mehdi, Hosseinzadeh, Mihaela, Hostiuc, Sorin, Hostiuc, Mowafa, Househ, Junjie, Huang, Ayesha, Humayun, Iavicoli, Ivo, Charles, U, Ibeneme, Segun, Ibitoye, E, Olayinka, S, Ilesanmi, Irena, Milena, D, Ilic, Usman, Iqbal, Seyed, Sina, Irvani, N, Sheikh, Mohammed, Shariful, Islam, Rakibul, M, Islam, Hiroyasu, Iso, Masao, Iwagami, Vardhmaan, Jain, Tahereh, Javaheri, Sathish, Kumar, Jayapal, Shubha, Jayaram, Ranil, Jayawardena, Panniyammakal, Jeemon, Ravi, P, Jha, Jost, Jonas, B, Jitendra, Jonnagaddala, Farahnaz, Joukar, Jacek, J, Jozwiak, Mikk, Jürisson, Ali, Kabir, Tanvir, Kahlon, Rizwan, Kalani, Rohollah, Kalhor, Ashwin, Kamath, Ibrahim, Kamel, Himal, Kandel, Amit, Kandel, André, Karch, Ayele, Semachew, Kasa, Patrick, D, M, Katoto, C, Gbenga, A, Kayode, Yousef, Khader, S, Mohammad, Khammarnia, Muhammad, S, Khan, Md, Nuruzzaman, Khan, Maseer, Khan, Ejaz, A, Khan, Khaled, Khatab, Gulam, M, Kibria, A, Yun, Jin, Kim, Gyu, Kim, Ri, Ruth, W, Kimokoti, Sezer, Kisa, Adnan, Kisa, Mika, Kivimäki, Dhaval, Kolte, Ali, Koolivand, Vladimir, A, Korshunov, Sindhura, Lakshmi, Koulmane, Laxminarayana, Koyanagi, Ai, Kewal, Krishan, Vijay, Krishnamoorthy, Barthelemy, Kuate, Defo, Burcu, Kucuk, Bicer, Vaman, Kulkarni, Anil, G, Kumar, Nithin, Kumar, Om, P, Kurmi, Dian, Kusuma, Gene, F, Kwan, Carlo, Vecchia, La, Ben, Lacey, Tea, Lallukka, Qing, Lan, Savita, Lasrado, Zohra, S, Lassi, Paolo, Lauriola, Wayne, R, Lawrence, Avula, Laxmaiah, Kate, E, Legrand, Ming-Chieh, Li, Bingyu, Li, Shanshan, Li, Stephen, S, Lim, Lee-Ling, Lim, Hualiang, Lin, Ziqiang, Lin, Ro-Ting, Lin, Xuefeng, Liu, Alan, D, Lopez, Stefan, Lorkowski, Paulo, A, Lotufo, Alessandra, Lugo, Nirmal, K, M, Fabiana, Madotto, Morteza, Mahmoudi, Azeem, Majeed, Reza, Malekzadeh, Ahmad, A, Malik, Abdullah, Navid, Manafi, Mohammad, Ali, Mansournia, Lorenzo, Mantovani, G, Santi, Martini, Manu, R, Mathur, Giampiero, Mazzaglia, Suresh, Mehata, Man, Mohan, Mehndiratta, Toni, Meier, Ritesh, G, Menezes, Atte, Meretoja, Tomislav, Mestrovic, Bartosz, Miazgowski, Tomasz, Miazgowski, Irmina, Maria, Michalek, Ted, Miller, R, Erkin, M, Mirrakhimov, Hamed, Mirzaei, Babak, Moazen, Masoud, Moghadaszadeh, Yousef, Mohammad, Dara, K, Mohammad, Shafiu, Mohammed, Mohammed, A, Mohammed, Yaser, Mokhayeri, Mariam, Molokhia, Ahmed, A, Montasir, Ghobad, Moradi, Rahmatollah, Moradzadeh, Paula, Moraga, Lidia, Morawska, Ilais, Moreno, Velásquez, Jakub, Morze, Sumaira, Mubarik, Walter, Muruet, Kamarul, Imran, Musa, Ahamarshan, Nagarajan, J, Mahdi, Nalini, Vinay, Nangia, Atta, Abba, Naqvi, Sreeniva, Narasimha, Swamy, Bruno, R, Nascimento, Vinod, Nayak, C, Javad, Nazari, Milad, Nazarzadeh, Ruxandra, I, Negoi, Sandhya, Neupane, Kandel, Huong, L, Nguyen, T, Molly, R, Nixon, Norrving, Bo, Jean, Jacque, Noubiap, Brice, Nouthe, E, Christoph, Nowak, Oluwakemi, O, Odukoya, Felix, Ogbo, A, Andrew, T, Olagunju, Hans, Orru, Alberto, Ortiz, Samuel, M, Ostroff, Jagadish, Rao, Padubidri, Palladino, Raffaele, Adrian, Pana, Songhomitra, Panda-Jona, Utsav, Parekh, Eun-Cheol, Park, Mojtaba, Parvizi, Fatemeh, Pashazadeh, Kan, Urvish, Patel, K, Mona, Pathak, Rajan, Paudel, Veincent, Christian, Pepito, F, Arokiasamy, Perianayagam, Norberto, Perico, Hai, Q, Pham, Thomas, Pilgrim, Michael, A, Piradov, Farhad, Pishgar, Vivek, Podder, Roman, V, Polibin, Akram, Poursham, Dimas, R, Pribadi, A, Navid, Rabiee, Mohammad, Rabiee, Amir, Radfar, Alireza, Rafiei, Fakher, Rahim, Vafa, Rahimi-Movaghar, Mohammad, Hifz, Rahman, Ur, Muhammad, Aziz, Rahman, Amir, Masoud, Rahmani, Ivo, Rakovac, Pradhum, Ram, Sudha, Ramalingam, Juwel, Rana, Priyanga, Ranasinghe, Sowmya, J, Rao, Priya, Rathi, Lal, Rawal, Wasiq, F, Rawasia, Reza, Rawassizadeh, Giuseppe, Remuzzi, Andre, M, Renzaho, N, Aziz, Rezapour, Seyed, Mohammad, Riahi, Ro, Roberts-Thomson, L, Leonardo, Roever, Peter, Rohloff, Michele, Romoli, Gholamreza, Roshandel, Godfrey, M, Rwegerera, Seyedmohammad, Saadatagah, Maha, M, Saber-Ayad, Siamak, Sabour, Simona, Sacco, Masoumeh, Sadeghi, Sahar, Saeedi, Moghaddam, Saeed, Safari, Amirhossein, Sahebkar, Sana, Salehi, Hamideh, Salimzadeh, Mehrnoosh, Samaei, Abdallah, M, Samy, Itamar, Santos, S, Milena, M, Santric-Milicevic, Nizal, Sarrafzadegan, Arash, Sarveazad, Thirunavukkarasu, Sathish, Monika, Sawhney, Mete, Saylan, Maria, I, Schmidt, Aletta, Schutte, E, Subramanian, Senthilkumaran, Sadaf, G, Sepanlou, Feng, Sha, Saeed, Shahabi, Izza, Shahid, Masood, A, Shaikh, Mahdi, Shamali, Morteza, Shamsizadeh, Shajedur, Md, Rahman, Shawon, Aziz, Sheikh, Mika, Shigematsu, Min-Jeong, Shin, Jae, Il, Shin, Rahman, Shiri, Ivy, Shiue, Kerem, Shuval, Soraya, Siabani, Tariq, J, Siddiqi, Diego, A, S, Silva, Jasvinder, Singh, A, Ambrish, Singh, Mtech, Valentin, Skryabin, Y, Anna, A, Skryabina, Amin, Soheili, Emma, E, Spurlock, Leo, Stockfelt, Stefan, Stortecky, Saverio, Strange, Rizwan, Suliankatchi, Abdulkader, Hooman, Tadbiri, Eyayou, G, Tadesse, Degena, Tadesse, B, Masih, Tajdini, Tariqujjaman, Md, Berhane, F, Teklehaimanot, Mohamad-Hani, Temsah, Ayenew, K, Tesema, Bhaskar, Thakur, Kavumpurathu, R, Thankappan, Rekha, Thapar, Amanda, G, Thrift, Binod, Timalsina, Marcello, Tonelli, Mathilde, Touvier, Marcos, R, Tovani-Palone, Avnish, Tripathi, Jaya, P, Tripathy, Thoma, Truelsen, C, Guesh, M, Tsegay, Gebiyaw, Tsegaye, W, Nikolaos, Tsilimpari, Biruk, S, Tusa, Stefanos, Tyrovola, Krishna, Kishore, Umapathi, Brigid, Unim, Bhaskaran, Unnikrishnan, Usman, Muthiah, Vaduganathan, Pascual, R, Valdez, Tommi, Vasankari, J, Diana, Z, Velazquez, Narayanaswamy, Venketasubramanian, Giang, T, Isidora, Vu, Vujcic, S, Yasir, Waheed, Yanzhong, Wang, Fang, Wang, Jingkai, Wei, Robert, G, Weintraub, Abrha, Weldemariam, H, Ronny, Westerman, Andrea, S, Winkler, Charle, Wiysonge, S, Charles, D, Wolfe, A, Befikadu, Legesse, Wubishet, Gelin, Xu, Ali, Yadollahpour, Kazumasa, Yamagishi, Lijing, L, Yan, Srikanth, Yandrapalli, Yuichiro, Yano, Hiroshi, Yatsuya, Tomas, Y, Yeheyis, Yigizie, Yeshaw, Christopher, S, Yilgwan, Naohiro, Yonemoto, Chuanhua, Yu, Hasan, Yusefzadeh, Geevar, Zachariah, Sojib, Bin, Zaman, Muhammed, Maryam, Zamanian, Ramin, Zand, Alireza, Zandifar, Afshin, Zarghi, Mikhail, S, Zastrozhin, Anasthasia, Zastrozhina, Zhi-Jiang, Zhang, Yunquan, Zhang, Wangjian, Zhang, Chenwen, Zhong, Zhiyong, Zou, Yves, Miel, Zuniga, H, Christopher, J, Murray, L, and Valentin, Fuster
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cardiovascular disease ,global health ,health policy ,population health - Abstract
Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019. Prevalent cases of total CVD nearly doubled from 271 million (95% uncertainty interval [UI]: 257 to 285 million) in 1990 to 523 million (95% UI: 497 to 550 million) in 2019, and the number of CVD deaths steadily increased from 12.1 million (95% UI:11.4 to 12.6 million) in 1990, reaching 18.6 million (95% UI: 17.1 to 19.7 million) in 2019. The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. The total number of DALYs due to IHD has risen steadily since 1990, reaching 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) deaths in the year 2019, and 197 million (95% UI: 178 to 220 million) prevalent cases of IHD in 2019. The total number of DALYs due to stroke has risen steadily since 1990, reaching 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) deaths in the year 2019, and 101 million (95% UI: 93.2 to 111 million) prevalent cases of stroke in 2019. Cardiovascular diseases remain the leading cause of disease burden in the world. CVD burden continues its decades-long rise for almost all countries outside high-income countries, and alarmingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously declining in high-income countries. There is an urgent need to focus on implementing existing cost-effective policies and interventions if the world is to meet the targets for Sustainable Development Goal 3 and achieve a 30% reduction in premature mortality due to noncommunicable diseases.
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- 2020
16. The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2019.
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Cunha ARD, Compton K, Xu R, Mishra R, Drangsholt MT, Antunes JLF, Kerr AR, Acheson AR, Lu D, Wallace LE, Kocarnik JM, Fu W, Dean FE, Pennini A, Henrikson HJ, Alam T, Ababneh E, Abd-Elsalam S, Abdoun M, Abidi H, Abubaker Ali H, Abu-Gharbieh E, Adane TD, Addo IY, Ahmad A, Ahmad S, Ahmed Rashid T, Akonde M, Al Hamad H, Alahdab F, Alimohamadi Y, Alipour V, Al-Maweri SA, Alsharif U, Ansari-Moghaddam A, Anwar SL, Anyasodor AE, Arabloo J, Aravkin AY, Aruleba RT, Asaad M, Ashraf T, Athari SS, Attia S, Azadnajafabad S, Azangou-Khyavy M, Badar M, Baghcheghi N, Banach M, Bardhan M, Barqawi HJ, Bashir NZ, Bashiri A, Benzian H, Bernabe E, Bhagat DS, Bhojaraja VS, Bjørge T, Bouaoud S, Braithwaite D, Briko NI, Calina D, Carreras G, Chakraborty PA, Chattu VK, Chaurasia A, Chen MX, Cho WCS, Chu DT, Chukwu IS, Chung E, Cruz-Martins N, Dadras O, Dai X, Dandona L, Dandona R, Daneshpajouhnejad P, Darvishi Cheshmeh Soltani R, Darwesh AM, Debela SA, Derbew Molla M, Dessalegn FN, Dianati-Nasab M, Digesa LE, Dixit SG, Dixit A, Djalalinia S, El Sayed I, El Tantawi M, Enyew DB, Erku DA, Ezzeddini R, Fagbamigbe AF, Falzone L, Fetensa G, Fukumoto T, Gaewkhiew P, Gallus S, Gebrehiwot M, Ghashghaee A, Gill PS, Golechha M, Goleij P, Gomez RS, Gorini G, Guimaraes ALS, Gupta B, Gupta S, Gupta VB, Gupta VK, Haj-Mirzaian A, Halboub ES, Halwani R, Hanif A, Hariyani N, Harorani M, Hasani H, Hassan AM, Hassanipour S, Hassen MB, Hay SI, Hayat K, Herrera-Serna BY, Holla R, Horita N, Hosseinzadeh M, Hussain S, Ilesanmi OS, Ilic IM, Ilic MD, Isola G, Jaiswal A, Jani CT, Javaheri T, Jayarajah U, Jayaram S, Joseph N, Kadashetti V, Kandaswamy E, Karanth SD, Karaye IM, Kauppila JH, Kaur H, Keykhaei M, Khader YS, Khajuria H, Khanali J, Khatib MN, Khayat Kashani HR, Khazeei Tabari MA, Kim MS, Kompani F, Koohestani HR, Kumar GA, Kurmi OP, La Vecchia C, Lal DK, Landires I, Lasrado S, Ledda C, Lee YH, Libra M, Lim SS, Listl S, Lopukhov PD, Mafi AR, Mahumud RA, Malik AA, Mathur MR, Maulud SQ, Meena JK, Mehrabi Nasab E, Mestrovic T, Mirfakhraie R, Misganaw A, Misra S, Mithra P, Mohammad Y, Mohammadi M, Mohammadi E, Mokdad AH, Moni MA, Moraga P, Morrison SD, Mozaffari HR, Mubarik S, Murray CJL, Nair TS, Narasimha Swamy S, Narayana AI, Nassereldine H, Natto ZS, Nayak BP, Negru SM, Nggada HA, Nouraei H, Nuñez-Samudio V, Oancea B, Olagunju AT, Omar Bali A, Padron-Monedero A, Padubidri JR, Pandey A, Pardhan S, Patel J, Pezzani R, Piracha ZZ, Rabiee N, Radhakrishnan V, Radhakrishnan RA, Rahmani AM, Rahmanian V, Rao CR, Rao SJ, Rath GK, Rawaf DL, Rawaf S, Rawassizadeh R, Razeghinia MS, Rezaei N, Rezaei N, Rezaei N, Rezapour A, Riad A, Roberts TJ, Romero-Rodríguez E, Roshandel G, S M, S N C, Saddik B, Saeb MR, Saeed U, Safaei M, Sahebazzamani M, Sahebkar A, Salek Farrokhi A, Samy AM, Santric-Milicevic MM, Sathian B, Satpathy M, Šekerija M, Senthilkumaran S, Seylani A, Shafaat O, Shahsavari HR, Shamsoddin E, Sharew MM, Sharifi-Rad J, Shetty JK, Shivakumar KM, Shobeiri P, Shorofi SA, Shrestha S, Siddappa Malleshappa SK, Singh P, Singh JA, Singh G, Sinha DN, Solomon Y, Suleman M, Suliankatchi Abdulkader R, Taheri Abkenar Y, Talaat IM, Tan KK, Tbakhi A, Thiyagarajan A, Tiyuri A, Tovani-Palone MR, Unnikrishnan B, Vo B, Volovat SR, Wang C, Westerman R, Wickramasinghe ND, Xiao H, Yu C, Yuce D, Yunusa I, Zadnik V, Zare I, Zhang ZJ, Zoladl M, Force LM, and Hugo FN
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- Adult, Female, Humans, Male, Global Health, Incidence, Lip, Quality-Adjusted Life Years, Risk Factors, Tobacco Use epidemiology, Global Burden of Disease, Pharyngeal Neoplasms epidemiology
- Abstract
Importance: Lip, oral, and pharyngeal cancers are important contributors to cancer burden worldwide, and a comprehensive evaluation of their burden globally, regionally, and nationally is crucial for effective policy planning., Objective: To analyze the total and risk-attributable burden of lip and oral cavity cancer (LOC) and other pharyngeal cancer (OPC) for 204 countries and territories and by Socio-demographic Index (SDI) using 2019 Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study estimates., Evidence Review: The incidence, mortality, and disability-adjusted life years (DALYs) due to LOC and OPC from 1990 to 2019 were estimated using GBD 2019 methods. The GBD 2019 comparative risk assessment framework was used to estimate the proportion of deaths and DALYs for LOC and OPC attributable to smoking, tobacco, and alcohol consumption in 2019., Findings: In 2019, 370 000 (95% uncertainty interval [UI], 338 000-401 000) cases and 199 000 (95% UI, 181 000-217 000) deaths for LOC and 167 000 (95% UI, 153 000-180 000) cases and 114 000 (95% UI, 103 000-126 000) deaths for OPC were estimated to occur globally, contributing 5.5 million (95% UI, 5.0-6.0 million) and 3.2 million (95% UI, 2.9-3.6 million) DALYs, respectively. From 1990 to 2019, low-middle and low SDI regions consistently showed the highest age-standardized mortality rates due to LOC and OPC, while the high SDI strata exhibited age-standardized incidence rates decreasing for LOC and increasing for OPC. Globally in 2019, smoking had the greatest contribution to risk-attributable OPC deaths for both sexes (55.8% [95% UI, 49.2%-62.0%] of all OPC deaths in male individuals and 17.4% [95% UI, 13.8%-21.2%] of all OPC deaths in female individuals). Smoking and alcohol both contributed to substantial LOC deaths globally among male individuals (42.3% [95% UI, 35.2%-48.6%] and 40.2% [95% UI, 33.3%-46.8%] of all risk-attributable cancer deaths, respectively), while chewing tobacco contributed to the greatest attributable LOC deaths among female individuals (27.6% [95% UI, 21.5%-33.8%]), driven by high risk-attributable burden in South and Southeast Asia., Conclusions and Relevance: In this systematic analysis, disparities in LOC and OPC burden existed across the SDI spectrum, and a considerable percentage of burden was attributable to tobacco and alcohol use. These estimates can contribute to an understanding of the distribution and disparities in LOC and OPC burden globally and support cancer control planning efforts.
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- 2023
- Full Text
- View/download PDF
17. Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019.
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Kocarnik JM, Compton K, Dean FE, Fu W, Gaw BL, Harvey JD, Henrikson HJ, Lu D, Pennini A, Xu R, Ababneh E, Abbasi-Kangevari M, Abbastabar H, Abd-Elsalam SM, Abdoli A, Abedi A, Abidi H, Abolhassani H, Adedeji IA, Adnani QES, Advani SM, Afzal MS, Aghaali M, Ahinkorah BO, Ahmad S, Ahmad T, Ahmadi A, Ahmadi S, Ahmed Rashid T, Ahmed Salih Y, Akalu GT, Aklilu A, Akram T, Akunna CJ, Al Hamad H, Alahdab F, Al-Aly Z, Ali S, Alimohamadi Y, Alipour V, Aljunid SM, Alkhayyat M, Almasi-Hashiani A, Almasri NA, Al-Maweri SAA, Almustanyir S, Alonso N, Alvis-Guzman N, Amu H, Anbesu EW, Ancuceanu R, Ansari F, Ansari-Moghaddam A, Antwi MH, Anvari D, Anyasodor AE, Aqeel M, Arabloo J, Arab-Zozani M, Aremu O, Ariffin H, Aripov T, Arshad M, Artaman A, Arulappan J, Asemi Z, Asghari Jafarabadi M, Ashraf T, Atorkey P, Aujayeb A, Ausloos M, Awedew AF, Ayala Quintanilla BP, Ayenew T, Azab MA, Azadnajafabad S, Azari Jafari A, Azarian G, Azzam AY, Badiye AD, Bahadory S, Baig AA, Baker JL, Balakrishnan S, Banach M, Bärnighausen TW, Barone-Adesi F, Barra F, Barrow A, Behzadifar M, Belgaumi UI, Bezabhe WMM, Bezabih YM, Bhagat DS, Bhagavathula AS, Bhardwaj N, Bhardwaj P, Bhaskar S, Bhattacharyya K, Bhojaraja VS, Bibi S, Bijani A, Biondi A, Bisignano C, Bjørge T, Bleyer A, Blyuss O, Bolarinwa OA, Bolla SR, Braithwaite D, Brar A, Brenner H, Bustamante-Teixeira MT, Butt NS, Butt ZA, Caetano Dos Santos FL, Cao Y, Carreras G, Catalá-López F, Cembranel F, Cerin E, Cernigliaro A, Chakinala RC, Chattu SK, Chattu VK, Chaturvedi P, Chimed-Ochir O, Cho DY, Christopher DJ, Chu DT, Chung MT, Conde J, Cortés S, Cortesi PA, Costa VM, Cunha AR, Dadras O, Dagnew AB, Dahlawi SMA, Dai X, Dandona L, Dandona R, Darwesh AM, das Neves J, De la Hoz FP, Demis AB, Denova-Gutiérrez E, Dhamnetiya D, Dhimal ML, Dhimal M, Dianatinasab M, Diaz D, Djalalinia S, Do HP, Doaei S, Dorostkar F, Dos Santos Figueiredo FW, Driscoll TR, Ebrahimi H, Eftekharzadeh S, El Tantawi M, El-Abid H, Elbarazi I, Elhabashy HR, Elhadi M, El-Jaafary SI, Eshrati B, Eskandarieh S, Esmaeilzadeh F, Etemadi A, Ezzikouri S, Faisaluddin M, Faraon EJA, Fares J, Farzadfar F, Feroze AH, Ferrero S, Ferro Desideri L, Filip I, Fischer F, Fisher JL, Foroutan M, Fukumoto T, Gaal PA, Gad MM, Gadanya MA, Gallus S, Gaspar Fonseca M, Getachew Obsa A, Ghafourifard M, Ghashghaee A, Ghith N, Gholamalizadeh M, Gilani SA, Ginindza TG, Gizaw ATT, Glasbey JC, Golechha M, Goleij P, Gomez RS, Gopalani SV, Gorini G, Goudarzi H, Grosso G, Gubari MIM, Guerra MR, Guha A, Gunasekera DS, Gupta B, Gupta VB, Gupta VK, Gutiérrez RA, Hafezi-Nejad N, Haider MR, Haj-Mirzaian A, Halwani R, Hamadeh RR, Hameed S, Hamidi S, Hanif A, Haque S, Harlianto NI, Haro JM, Hasaballah AI, Hassanipour S, Hay RJ, Hay SI, Hayat K, Heidari G, Heidari M, Herrera-Serna BY, Herteliu C, Hezam K, Holla R, Hossain MM, Hossain MBH, Hosseini MS, Hosseini M, Hosseinzadeh M, Hostiuc M, Hostiuc S, Househ M, Hsairi M, Huang J, Hugo FN, Hussain R, Hussein NR, Hwang BF, Iavicoli I, Ibitoye SE, Ida F, Ikuta KS, Ilesanmi OS, Ilic IM, Ilic MD, Irham LM, Islam JY, Islam RM, Islam SMS, Ismail NE, Isola G, Iwagami M, Jacob L, Jain V, Jakovljevic MB, Javaheri T, Jayaram S, Jazayeri SB, Jha RP, Jonas JB, Joo T, Joseph N, Joukar F, Jürisson M, Kabir A, Kahrizi D, Kalankesh LR, Kalhor R, Kaliyadan F, Kalkonde Y, Kamath A, Kameran Al-Salihi N, Kandel H, Kapoor N, Karch A, Kasa AS, Katikireddi SV, Kauppila JH, Kavetskyy T, Kebede SA, Keshavarz P, Keykhaei M, Khader YS, Khalilov R, Khan G, Khan M, Khan MN, Khan MAB, Khang YH, Khater AM, Khayamzadeh M, Kim GR, Kim YJ, Kisa A, Kisa S, Kissimova-Skarbek K, Kopec JA, Koteeswaran R, Koul PA, Koulmane Laxminarayana SL, Koyanagi A, Kucuk Bicer B, Kugbey N, Kumar GA, Kumar N, Kumar N, Kurmi OP, Kutluk T, La Vecchia C, Lami FH, Landires I, Lauriola P, Lee SW, Lee SWH, Lee WC, Lee YH, Leigh J, Leong E, Li J, Li MC, Liu X, Loureiro JA, Lunevicius R, Magdy Abd El Razek M, Majeed A, Makki A, Male S, Malik AA, Mansournia MA, Martini S, Masoumi SZ, Mathur P, McKee M, Mehrotra R, Mendoza W, Menezes RG, Mengesha EW, Mesregah MK, Mestrovic T, Miao Jonasson J, Miazgowski B, Miazgowski T, Michalek IM, Miller TR, Mirzaei H, Mirzaei HR, Misra S, Mithra P, Moghadaszadeh M, Mohammad KA, Mohammad Y, Mohammadi M, Mohammadi SM, Mohammadian-Hafshejani A, Mohammed S, Moka N, Mokdad AH, Molokhia M, Monasta L, Moni MA, Moosavi MA, Moradi Y, Moraga P, Morgado-da-Costa J, Morrison SD, Mosapour A, Mubarik S, Mwanri L, Nagarajan AJ, Nagaraju SP, Nagata C, Naimzada MD, Nangia V, Naqvi AA, Narasimha Swamy S, Ndejjo R, Nduaguba SO, Negoi I, Negru SM, Neupane Kandel S, Nguyen CT, Nguyen HLT, Niazi RK, Nnaji CA, Noor NM, Nuñez-Samudio V, Nzoputam CI, Oancea B, Ochir C, Odukoya OO, Ogbo FA, Olagunju AT, Olakunde BO, Omar E, Omar Bali A, Omonisi AEE, Ong S, Onwujekwe OE, Orru H, Ortega-Altamirano DV, Otstavnov N, Otstavnov SS, Owolabi MO, P A M, Padubidri JR, Pakshir K, Pana A, Panagiotakos D, Panda-Jonas S, Pardhan S, Park EC, Park EK, Pashazadeh Kan F, Patel HK, Patel JR, Pati S, Pattanshetty SM, Paudel U, Pereira DM, Pereira RB, Perianayagam A, Pillay JD, Pirouzpanah S, Pishgar F, Podder I, Postma MJ, Pourjafar H, Prashant A, Preotescu L, Rabiee M, Rabiee N, Radfar A, Radhakrishnan RA, Radhakrishnan V, Rafiee A, Rahim F, Rahimzadeh S, Rahman M, Rahman MA, Rahmani AM, Rajai N, Rajesh A, Rakovac I, Ram P, Ramezanzadeh K, Ranabhat K, Ranasinghe P, Rao CR, Rao SJ, Rawassizadeh R, Razeghinia MS, Renzaho AMN, Rezaei N, Rezaei N, Rezapour A, Roberts TJ, Rodriguez JAB, Rohloff P, Romoli M, Ronfani L, Roshandel G, Rwegerera GM, S M, Sabour S, Saddik B, Saeed U, Sahebkar A, Sahoo H, Salehi S, Salem MR, Salimzadeh H, Samaei M, Samy AM, Sanabria J, Sankararaman S, Santric-Milicevic MM, Sardiwalla Y, Sarveazad A, Sathian B, Sawhney M, Saylan M, Schneider IJC, Sekerija M, Seylani A, Shafaat O, Shaghaghi Z, Shaikh MA, Shamsoddin E, Shannawaz M, Sharma R, Sheikh A, Sheikhbahaei S, Shetty A, Shetty JK, Shetty PH, Shibuya K, Shirkoohi R, Shivakumar KM, Shivarov V, Siabani S, Siddappa Malleshappa SK, Silva DAS, Singh JA, Sintayehu Y, Skryabin VY, Skryabina AA, Soeberg MJ, Sofi-Mahmudi A, Sotoudeh H, Steiropoulos P, Straif K, Subedi R, Sufiyan MB, Sultan I, Sultana S, Sur D, Szerencsés V, Szócska M, Tabarés-Seisdedos R, Tabuchi T, Tadbiri H, Taherkhani A, Takahashi K, Talaat IM, Tan KK, Tat VY, Tedla BAA, Tefera YG, Tehrani-Banihashemi A, Temsah MH, Tesfay FH, Tessema GA, Thapar R, Thavamani A, Thoguluva Chandrasekar V, Thomas N, Tohidinik HR, Touvier M, Tovani-Palone MR, Traini E, Tran BX, Tran KB, Tran MTN, Tripathy JP, Tusa BS, Ullah I, Ullah S, Umapathi KK, Unnikrishnan B, Upadhyay E, Vacante M, Vaezi M, Valadan Tahbaz S, Velazquez DZ, Veroux M, Violante FS, Vlassov V, Vo B, Volovici V, Vu GT, Waheed Y, Wamai RG, Ward P, Wen YF, Westerman R, Winkler AS, Yadav L, Yahyazadeh Jabbari SH, Yang L, Yaya S, Yazie TSY, Yeshaw Y, Yonemoto N, Younis MZ, Yousefi Z, Yu C, Yuce D, Yunusa I, Zadnik V, Zare F, Zastrozhin MS, Zastrozhina A, Zhang J, Zhong C, Zhou L, Zhu C, Ziapour A, Zimmermann IR, Fitzmaurice C, Murray CJL, and Force LM
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- Disability-Adjusted Life Years, Global Health, Humans, Incidence, Prevalence, Quality-Adjusted Life Years, Risk Factors, Global Burden of Disease, Neoplasms epidemiology
- Abstract
Importance: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden., Objective: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019., Evidence Review: The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs)., Findings: In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles., Conclusions and Relevance: The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world.
- Published
- 2022
- Full Text
- View/download PDF
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