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2. Prediction of plasma ctDNA fraction and prognostic implications of liquid biopsy in advanced prostate cancer

Author

Fonseca, Nicolette M., Maurice-Dror, Corinne, Herberts, Cameron, Tu, Wilson, Fan, William, Murtha, Andrew J., Kollmannsberger, Catarina, Kwan, Edmond M., Parekh, Karan, Schönlau, Elena, Bernales, Cecily Q., Donnellan, Gráinne, Ng, Sarah W. S., Sumiyoshi, Takayuki, Vergidis, Joanna, Noonan, Krista, Finch, Daygen L., Zulfiqar, Muhammad, Miller, Stacy, Parimi, Sunil, Lavoie, Jean-Michel, Hardy, Edward, Soleimani, Maryam, Nappi, Lucia, Eigl, Bernhard J., Kollmannsberger, Christian, Taavitsainen, Sinja, Nykter, Matti, Tolmeijer, Sofie H., Boerrigter, Emmy, Mehra, Niven, van Erp, Nielka P., De Laere, Bram, Lindberg, Johan, Grönberg, Henrik, Khalaf, Daniel J., Annala, Matti, Chi, Kim N., and Wyatt, Alexander W.

Published
2024
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5. MP01-06 miRNA AS A LIQUID BIOMARKER TO DETECT MALIGNANCY IN SMALL TESTICULAR MASSES

Author

Chavarriaga, Julian, primary, Langleben, Carley, additional, Lobo, João, additional, Nappi, Lucia, additional, Yousef, George M., additional, Janfaza, Sajjad, additional, Tavares, Nuno Tiago, additional, Ding, Qiang, additional, Bobrowski, Adam, additional, Prendeville, Susan, additional, Anson-Cartwright, Lynn, additional, Jeronimo, Carmen, additional, Wagner, Heidi, additional, Jarvi, Keith, additional, O’Malley, Martin, additional, Leão, Ricardo, additional, Lajkopsz, Katherine, additional, and Hamilton, Robert J., additional

Published
2024
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6. MP01-12 ACCURACY OF FDG-PET SCAN IN PRIMARY TESTICULAR SEMINOMA: ANALYSIS FROM SEMS TRIAL

Author

Hu, Brian R., primary, Alsyouf, Muhannad, additional, Cary, Clint, additional, Masterson, Timothy, additional, Einhorn, Lawrence, additional, Adra, Nabil, additional, Boorjian, Stephen, additional, Kollmannsberger, Christian, additional, Schuckman, Anne, additional, So, Alan, additional, Black, Peter, additional, Bagrodia, Aditya, additional, Skinner, Eila, additional, Alemozaffar, Mehrdad, additional, Brand, Timothy, additional, Eggener, Scott, additional, Pierorazio, Phillip, additional, Stratton, Kelly, additional, Nappi, Lucia, additional, Nichols, Craig, additional, and Daneshmand, Siamak, additional

Published
2024
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8. Plasma exosome microRNA-155-3p expression in patients with metastatic renal cell carcinoma treated with immune checkpoint inhibitors: a potential biomarker of response to systemic therapy

Author

Soleimani, Maryam, primary, Thi, Marisa, additional, Janfaza, Sajjad, additional, Ozcan, Gizem, additional, Ozgun, Guliz, additional, Maurice-Dror, Corinne, additional, Eigl, Bernhard, additional, Chi, Kim, additional, Kollmannsberger, Christian, additional, and Nappi, Lucia, additional

Published
2023
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9. LIN28B promotes the development of neuroendocrine prostate cancer

Author

Lovnicki, Jessica, Gan, Yu, Feng, Tingting, Li, Yinan, Xie, Ning, Ho, Chia-Hao, Lee, Ahn R., Chen, Xufeng, Nappi, Lucia, Han, Bo, Fazli, Ladan, Huang, Jiaoti, Gleave, Martin E., and Dong, Xuesen

Subjects
Genetic engineering -- Health aspects -- Analysis, Enzalutamide -- Health aspects -- Analysis, Abiraterone -- Analysis -- Health aspects, Genes -- Analysis -- Health aspects, Prostate cancer -- Development and progression, Stem cells -- Health aspects -- Analysis, Chromosomal proteins -- Analysis -- Health aspects, Health care industry
Abstract

Therapy-induced neuroendocrine prostate cancer (t-NEPC) is a highly aggressive subtype of prostate cancer with poor patient survival. Emerging evidence indicates that t-NEPC can develop when prostate adenocarcinoma cells acquire cancer stem-like cell signaling in the presence of androgen receptor inhibition, followed by redifferentiation toward neuroendocrine lineage and subsequent t-NEPC progression. Whether the stem-like signaling is controlled by the core pluripotency stem cell genes (e.g., LIN28 and SOX2) remains unknown. Here, we report that the transcription of the LIN28B isoform and SOX2 were co-upregulated in t-NEPC patient tumors, patient-derived xenografts, transgenic mice, and cell models. Immunohistochemistry validated that LIN28B and SOX2 protein expression were elevated in t-NEPC patient biopsies. Using prostate adenocarcinoma and t-NEPC cell models, we demonstrated that LIN28B induced a stem-like gene network, neuroendocrine biomarkers, and neuroendocrine cell morphology. LIN28B depletion by CRISPR inhibited t-NEPC tumorigenesis and xenograft growth. These LIN28B functions were mediated mainly through the suppression of let-7 miRNA expression, resulting in de-repression of the transcription factor HMGA2 and HMGA2-mediated SOX2 expression. This study revealed a mechanism by which t-NEPC can develop through the LIN28B/let-7/SOX2 axis that regulates a cancer cell stem-like gene network, highlighting LIN28B as a potential therapeutic target in t-NEPC., Introduction New, potent androgen receptor (AR) pathway inhibitors (ARPIs) have improved overall survival in men with metastatic prostate cancer (PCa) (1, 2). However, more aggressive subtypes of castrate-resistant prostate cancer [...]

Published
2020
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10. Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models

Author

Nappi, Lucia, Aguda, Adeleke H., Nakouzi, Nader Al, Lelj-Garolla, Barbara, Beraldi, Eliana, Lallous, Nada, Thi, Marisa, Moore, Susan, Fazli, Ladan, Battsogt, Dulguun, Stief, Sophie, Ban, Fuqiang, Nguyen, Nham T., Saxena, Neetu, Dueva, Evgenia, Zhang, Fan, Yamazaki, Takeshi, Zoubeidi, Amina, Cherkasov, Artem, Brayer, Gary D., and Gleave, Martin

Subjects
Enzalutamide -- Analysis, Ivermectin -- Analysis, Tumors -- Genetic aspects -- Analysis, Heat shock proteins -- Analysis, Drug discovery -- Analysis, Biochemistry, Cancer, Serine, Health care industry
Abstract

HSP27 is highly expressed in, and supports oncogene addiction of, many cancers. HSP27 phosphorylation is a limiting step for activation of this protein and a target for inhibition, but its highly disordered structure challenges rational structure-guided drug discovery. We performed multistep biochemical, structural, and computational experiments to define a spherical 24-monomer complex composed of 12 HSP27 dimers with a phosphorylation pocket flanked by serine residues between their N-terminal domains. Ivermectin directly binds this pocket to inhibit MAPKAP2-mediated HSP27 phosphorylation and depolymerization, thereby blocking HSP27-regulated survival signaling and client-oncoprotein interactions. Ivermectin potentiated activity of anti-androgen receptor and anti-EGFR drugs in prostate and EGFR/HER2-driven tumor models, respectively, identifying a repurposing approach for cotargeting stress-adaptive responses to overcome resistance to inhibitors of oncogenic pathway signaling., Introduction Small heat shock proteins (sHSPs) are ATP-independent molecular chaperones characterized by a conserved [alpha]-crystallin domain located between a highly flexible, variable C-terminal region and a poorly conserved, disorganized N-terminal [...]

Published
2020
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12. Lack of Effectiveness of Postchemotherapy Lymphadenectomy in Bladder Cancer Patients with Clinical Evidence of Metastatic Pelvic or Retroperitoneal Lymph Nodes Only: A Propensity Score-based Analysis

Author

Necchi, Andrea, Mariani, Luigi, Lo Vullo, Salvatore, Yu, Evan Y., Woods, Michael E., Wong, Yu-Ning, Harshman, Lauren C., Alva, Ajjaj, Sternberg, Cora N., Bamias, Aristotelis, Grivas, Petros, Koshkin, Vadim S., Roghmann, Florian, Dobruch, Jakub, Eigl, Bernie J., Nappi, Lucia, Milowsky, Matthew I., Niegisch, Guenter, Pal, Sumanta K., De Giorgi, Ugo, Recine, Federica, Vaishampayan, Ulka, Berthold, Dominik D., Bowles, Daniel W., Baniel, Jack, Theodore, Christine, Ladoire, Sylvain, Srinivas, Sandy, Agarwal, Neeraj, Crabb, Simon, Sridhar, Srikala, Golshayan, Ali-Reza, Ohlmann, Carsten, Xylinas, Evanguelos, Powles, Thomas, Rosenberg, Johnathan E., Bellmunt, Joaquim, van Rhijn, Bas, Galsky, Matthew D., and Hendricksen, Kees

Published
2019
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14. The Use of Salvage Chemotherapy for Patients with Relapsed Testicular Germ Cell Tumor (GCT) in Canada: A National Survey

Author

Al-Ezzi, Esmail M., primary, Zahralliyali, Amer, additional, Hansen, Aaron R., additional, Hamilton, Robert J., additional, Crump, Michael, additional, Kuruvilla, John, additional, Wood, Lori, additional, Nappi, Lucia, additional, Kollmannsberger, Christian K., additional, North, Scott A., additional, Winquist, Eric, additional, Soulières, Denis, additional, Hotte, Sebastien J., additional, and Jiang, Di Maria, additional

Published
2023
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15. SWOG S1823/CCTG GCC1: Translational observational investigational study of the liquid biomarker microRNA 371a-3p in newly diagnosed germ cell tumours—Real-world trial design, rapid accrual, and robust secondary use of data opportunities.

Author

Morin Coulombe, Antoine, primary, Ozgun, Guliz, additional, Johnson, Rebecca, additional, Lewis, Mark Andrew, additional, Adra, Nabil, additional, Eggener, Scott E., additional, Roth, Bruce J., additional, Ryan, Christopher W., additional, Porter, Christopher, additional, Millard, Fred, additional, Jang, Thomas, additional, Hamilton, Robert James, additional, Einhorn, Lawrence H., additional, Kollmannsberger, Christian K., additional, Arnold, Kathryn B., additional, Blanke, Charles David, additional, Daneshmand, Siamak, additional, Nichols, Craig R., additional, Nappi, Lucia, additional, and Harzstark, Andrea, additional

Published
2023
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16. Clinical Outcomes of Perioperative Chemotherapy in Patients With Locally Advanced Penile Squamous-Cell Carcinoma: Results of a Multicenter Analysis

Author

Necchi, Andrea, Pond, Gregory R., Raggi, Daniele, Ottenhof, Sarah R., Djajadiningrat, Rosa S., Horenblas, Simon, Khoo, Vincent, Hakenberg, Oliver W., Draeger, Desiree, Protzel, Chris, Heidenreich, Axel, Haidl, Friederike, Eigl, Bernie J., Nappi, Lucia, Matsumoto, Kazumasa, Vaishampayan, Ulka, Woods, Michael E., Salvioni, Roberto, Nicolai, Nicola, Catanzaro, Mario, Giannatempo, Patrizia, Geynisman, Daniel M., Preto, Mirko, Xylinas, Evanguelos, Milowsky, Matthew I., De Placido, Sabino, Di Lorenzo, Giuseppe, and Sonpavde, Guru

Published
2017
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22. MP33-18 SURGICAL AND ONCOLOGIC OUTCOMES OF SURGERY IN EARLY METASTATIC SEMINOMA: MULTI-INSTITUTIONAL RETROSPECTIVE STUDY

Author

Ladi-Seyedian, Sanam, primary, Alsyouf, Muhannad, additional, Hu, Brian, additional, Cary, Clint, additional, Masterson, Timothy, additional, Einhorn, Lawrence, additional, Adra, Nabil, additional, Boorjian, Stephen A., additional, Kollmannsberger, Christian, additional, Schuckman, Anne, additional, So, Alan, additional, Black, Peter, additional, Bagrodia, Aditya, additional, Skinner, Eila, additional, Alemozaffar, Mehrdad, additional, Brand, Timothy, additional, Eggener, Scott, additional, Pierorazio, Phillip, additional, Stratton, Kelly, additional, Nappi, Lucia, additional, Nichols, Craig, additional, Heidenreich, Axel, additional, and Daneshmand, Siamak, additional

Published
2023
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23. Supplementary Methods from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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24. Supplementary Table 2 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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25. Supplementary Figure 6 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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26. Supplementary Figure Legend from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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27. Supplementary Figure 4 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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28. Supplementary Figure 3 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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29. Supplementary Figure 1 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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30. Supplementary Figure 2 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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31. Supplementary Table 1 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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32. Supplementary Figure 5 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Author

Rosa, Roberta, primary, Marciano, Roberta, primary, Malapelle, Umberto, primary, Formisano, Luigi, primary, Nappi, Lucia, primary, D'Amato, Claudia, primary, D'Amato, Valentina, primary, Damiano, Vincenzo, primary, Marfè, Gabriella, primary, Del Vecchio, Silvana, primary, Zannetti, Antonella, primary, Greco, Adelaide, primary, De Stefano, Alfonso, primary, Carlomagno, Chiara, primary, Veneziani, Bianca Maria, primary, Troncone, Giancarlo, primary, De Placido, Sabino, primary, and Bianco, Roberto, primary

Published
2023
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33. Surgery in Early Metastatic Seminoma: A Phase II Trial of Retroperitoneal Lymph Node Dissection for Testicular Seminoma With Limited Retroperitoneal Lymphadenopathy

Author

Daneshmand, Siamak, primary, Cary, Clint, additional, Masterson, Timothy, additional, Einhorn, Lawrence, additional, Adra, Nabil, additional, Boorjian, Stephen A., additional, Kollmannsberger, Christian, additional, Schuckman, Anne, additional, So, Alan, additional, Black, Peter, additional, Bagrodia, Aditya, additional, Skinner, Eila, additional, Alemozaffar, Mehrdad, additional, Brand, Timothy, additional, Eggener, Scott, additional, Pierorazio, Phillip, additional, Stratton, Kelly, additional, Nappi, Lucia, additional, Nichols, Craig, additional, Luo, Chunqiao, additional, Li, Ming, additional, and Hu, Brian, additional

Published
2023
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34. Real-world outcomes in patients with metastatic renal cell carcinoma (mRCC) receiving dual immune checkpoint inhibitor (ICI-ICI) regimens or immune checkpoint inhibitor and tyrosine kinase inhibitor (ICI-TKI) combinations as first-line therapy: A British Columbia (BC) population-based analysis.

Author

Morin Coulombe, Antoine, primary, Alsadoun, Faisal Abdullah, additional, Ye, Xin (Cynthia), additional, Soleimani, Maryam, additional, Nappi, Lucia, additional, Eigl, Bernhard J., additional, Chi, Kim N., additional, and Kollmannsberger, Christian K., additional

Published
2023
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35. Longitudinal evaluation of plasma miR371 to detect minimal residual disease and early relapse of germ cell tumors.

Author

Nappi, Lucia, primary, Saxena, Neetu, additional, Pautasso, Sara, additional, Mazurek, Sylwia, additional, Ozgun, Guliz, additional, Kollmannsberger, Catarina, additional, Trottier Chi, Max, additional, Morin Coulombe, Antoine, additional, Soleimani, Maryam, additional, Chi, Kim N., additional, Eigl, Bernhard J., additional, Black, Peter C., additional, So, Alan, additional, Gleave, Martin, additional, Kern, Sean, additional, Daneshmand, Siamak, additional, Adra, Nabil, additional, Einhorn, Lawrence H., additional, Nichols, Craig R., additional, and Kollmannsberger, Christian K., additional

Published
2023
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39. Exploring new frontiers in prostate cancer research: Report from the 2022 Coffey−Holden prostate cancer academy meeting

Author

Miyahira, Andrea K., primary, Hawley, Jessica E., additional, Adelaiye‐Ogala, Remi, additional, Calais, Jeremie, additional, Nappi, Lucia, additional, Parikh, Ravi, additional, Seibert, Tyler M., additional, Wasmuth, Elizabeth V., additional, Wei, Xiao X., additional, Pienta, Kenneth J., additional, and Soule, Howard R., additional

Published
2022
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40. TP53 Alterations Are Associated With Poor Survival in Patients With Primary Mediastinal Nonseminoma Germ Cell Tumors

Author

Bacon, Jack V W, primary, Giannatempo, Patrizia, additional, Cataldo, Giovanna, additional, Fazli, Ladan, additional, Saxena, Neetu, additional, Ozgun, Guliz, additional, Soleimani, Maryam, additional, Chi, Kim, additional, Nichols, Craig, additional, Necchi, Andrea, additional, Wyatt, Alexander W, additional, Kollmannsberger, Christian K, additional, and Nappi, Lucia, additional

Published
2022
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41. Comprehensive immune profiling of patients with advanced urothelial or renal cell carcinoma receiving immune checkpoint blockade

Author

Lavoie, Jean-Michel, primary, Baichoo, Priya, additional, Chavez, Elizabeth, additional, Nappi, Lucia, additional, Khalaf, Daniel, additional, Kollmannsberger, Christian K., additional, Chi, Kim N., additional, Weng, Andrew, additional, Steidl, Christian, additional, Eigl, Bernhard J., additional, and Nissen, Michael, additional

Published
2022
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43. Testicular cancer survivorship: Long-term toxicity and management

Author

Shrem, Noa Shani, primary, Wood, Lori, additional, Hamilton, Robert J., additional, Kuhathaas, Kopika, additional, Czaykowski, Piotr, additional, Roberts, Matthew, additional, Matthew, Andrew, additional, Izard, Jason, additional, Chung, Peter, additional, Nappi, Lucia, additional, Jones, Jennifer, additional, Soulières, Denis, additional, Aprikian, Armen, additional, Power, Nicholas, additional, and Canil, Christina, additional

Published
2022
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46. PD51-01 CONTEMPORARY SURGICAL OUTCOMES OF RETROPERITONEAL LYMPH NODE DISSECTION FROM THE SEMS TRIAL

Author

Hu, Brian, primary, Alsyouf, Muhannad, additional, Cary, Clint, additional, Masterson, Timothy A., additional, Einhorn, Lawrence, additional, Boorjian, Stephen A., additional, Kollmannsberger, Christian K., additional, Schuckman, Anne K., additional, So, Alan, additional, Black, Peter C., additional, Bagrodia, Aditya, additional, Skinner, Eila C., additional, Alemozaffar, Mehrdad, additional, Brand, Timothy C., additional, Eggener, Scott E., additional, Pierorazio, Phillip M., additional, Stratton, Kelly Lynn, additional, Nappi, Lucia, additional, Nichols, Craig R., additional, and Daneshmand, Siamak, additional

Published
2022
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49. Effectiveness of first-line abiraterone versus enzalutamide among patients ≥80 years of age with metastatic castration-resistant prostate cancer: A retrospective propensity score–weighted comparative cohort study

Author

Soleimani, Maryam, primary, Zou, Kevin, additional, Sunderland, Katherine, additional, Struss, Werner, additional, Eigl, Bernie J., additional, Nappi, Lucia, additional, Kollmannsberger, Christian K., additional, Finch, Daygen, additional, Noonan, Krista, additional, Vergidis, Joanna, additional, Zulfiqar, Muhammad, additional, Chi, Kim N., additional, and Khalaf, Daniel J., additional

Published
2021
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50. Once Upon a Time.... Simple, Sensible Management of Venous Access for Chemotherapy Delivery in Germ Cell Tumors.

Author

Ozgun, Guliz, Haney, LaTrice, Kern, Sean, King, Jennifer, D'Souza, Anishka, Tandstad, Torgrim, Nappi, Lucia, Kollmannsberger, Christian, and Nichols, Craig R.

Subjects
THERAPEUTIC use of antineoplastic agents, NURSES, BLOOD vessels, INTRAVENOUS catheterization, DISEASE management, DRUG delivery systems, CENTRAL venous catheterization, TREATMENT duration, CANCER chemotherapy, PATIENT-centered care, ONCOLOGY nursing, MEDICAL equipment, CATHETERS, GERMINOMA, HEALTH promotion, PROFESSIONAL competence, TIME, MEDICAL care costs, PATIENTS' attitudes, TESTIS tumors
Abstract

The authors discuss a clinical study by H. Weisen and colleagues on patient-centered issue for delivery of multiday cisplatin chemotherapy. The researchers outlined the time, money, and patient burden costs for young patients with testis cancer. They discuss the factors associated with multiple-step processes required for central venous access. The authors offer their view on the use of peripheral venous access for delivery of bleomycin, etoposide, and cisplatin (BEP).

Published
2024
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