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1. Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review [version 2; peer review: 2 approved]

Author

Marie Williams, Naomi Clifford, Farhad Shokraneh, Naomi Thorpe, Avril Drummond, Jo Leonardi-Bee, Terry Quinn, Eirini Kontou, Roshan das Nair, and Sandra Wydera

Subjects
umbrella review, systematic review, stroke, Transient Ischaemic Attack, protocol, overview of systematic reviews, eng, Medicine, Science
Abstract

Background People who have had a stroke or a Transient Ischaemic Attack (TIA) can experience psychological and/or cognitive difficulties. The body of research for psychological and neuropsychological interventions after stroke is growing, however, published systematic reviews vary in scope and methodology, with different types and severity of strokes included, and at times, diverse conclusions drawn about the effectiveness of the interventions evaluated. In this umbrella review, we aim to systematically summarise the existing systematic reviews evaluating psychological interventions for mood and cognition post-stroke/TIA. Methods We will conduct this umbrella review according to the JBI Manual for Evidence Synthesis. The following databases will be searched from inception: Cochrane Database of Systematic Reviews, Database of Reviews of Effects (DARE), MEDLINE, Embase, CINAHL, PsycINFO, and Epistemonikos. Systematic reviews with or without meta-analysis published until the search date will be included. Reviews including psychological interventions addressing mood and/or cognition outcomes for any stroke type or severity will be screened for eligibility. A narrative synthesis, including content analysis, will be used. Each stage of the review will be processed by two independent reviewers and a third reviewer will be considered to resolve disagreements. The methodological quality of the included reviews will be assessed using AMSTAR 2. Discussion Existing systematic reviews provide varied evidence on the effectiveness of psychological interventions post-stroke/TIA. This umbrella review aims to summarise knowledge and evidence on different types of psychological and neuropsychological interventions targeting mood and cognition. Findings will highlight important knowledge gaps and help prioritise future research questions. Systematic Review Registration This protocol was prospectively registered with the International Prospective Register of Systematic Reviews (PROSPERO) on November 15, 2022; PROSPERO CRD42022375947.

Published
2024
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2. Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review [version 2; peer review: 1 approved, 1 approved with reservations]

Author

Eirini Kontou, Farhad Shokraneh, Roshan das Nair, Terry Quinn, Jo Leonardi-Bee, Naomi Thorpe, Naomi Clifford, Marie Williams, Sandra Wydera, and Avril Drummond

Subjects
Study Protocol, Articles, umbrella review, systematic review, stroke, Transient Ischaemic Attack, protocol, overview of systematic reviews, cognition, mood, psychological intervention, cognitive intervention
Abstract

Background People who have had a stroke or a Transient Ischaemic Attack (TIA) can experience psychological and/or cognitive difficulties. The body of research for psychological and neuropsychological interventions after stroke is growing, however, published systematic reviews vary in scope and methodology, with different types and severity of strokes included, and at times, diverse conclusions drawn about the effectiveness of the interventions evaluated. In this umbrella review, we aim to systematically summarise the existing systematic reviews evaluating psychological interventions for mood and cognition post-stroke/TIA. Methods We will conduct this umbrella review according to the JBI Manual for Evidence Synthesis. The following databases will be searched from inception: Cochrane Database of Systematic Reviews, Database of Reviews of Effects (DARE), MEDLINE, Embase, CINAHL, PsycINFO, and Epistemonikos. Systematic reviews with or without meta-analysis published until the search date will be included. Reviews including psychological interventions addressing mood and/or cognition outcomes for any stroke type or severity will be screened for eligibility. A narrative synthesis, including content analysis, will be used. Each stage of the review will be processed by two independent reviewers and a third reviewer will be considered to resolve disagreements. The methodological quality of the included reviews will be assessed using AMSTAR 2. Discussion Existing systematic reviews provide varied evidence on the effectiveness of psychological interventions post-stroke/TIA. This umbrella review aims to summarise knowledge and evidence on different types of psychological and neuropsychological interventions targeting mood and cognition. Findings will highlight important knowledge gaps and help prioritise future research questions. Systematic Review Registration This protocol was prospectively registered with the International Prospective Register of Systematic Reviews (PROSPERO) on November 15, 2022; PROSPERO CRD42022375947.

Published
2024
Full Text
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3. Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review [version 1; peer review: awaiting peer review]

Author

Eirini Kontou, Farhad Shokraneh, Roshan das Nair, Terry Quinn, Jo Leonardi-Bee, Naomi Thorpe, Naomi Clifford, Marie Williams, Sandra Wydera, and Avril Drummond

Subjects
Study Protocol, Articles, umbrella review, systematic review, stroke, Transient Ischaemic Attack, protocol, overview of systematic reviews, cognition, mood, psychological intervention, cognitive intervention
Abstract

Background People who have had a stroke or a Transient Ischaemic Attack (TIA) can experience psychological and/or cognitive difficulties. The body of research for psychological and neuropsychological interventions after stroke is growing, however, published systematic reviews vary in scope and methodology, with different types and severity of strokes included, and at times, diverse conclusions drawn about the effectiveness of the interventions evaluated. In this umbrella review, we aim to systematically summarise the existing systematic reviews evaluating psychological interventions for mood and cognition post-stroke/TIA. Methods We will conduct this umbrella review according to the JBI Manual for Evidence Synthesis. The following databases will be searched from inception: Cochrane Database of Systematic Reviews, Database of Reviews of Effects (DARE), MEDLINE, Embase, CINAHL, PsycINFO, and Epistemonikos. Systematic reviews with or without meta-analysis published until the search date will be included. Reviews including psychological interventions addressing mood and/or cognition outcomes for any stroke type or severity will be screened for eligibility. A narrative synthesis, including content analysis, will be used. Each stage of the review will be processed by two independent reviewers and a third reviewer will be considered to resolve disagreements. The methodological quality of the included reviews will be assessed using AMSTAR 2. Discussion Existing systematic reviews provide varied evidence on the effectiveness of psychological interventions post-stroke/TIA. This umbrella review aims to summarise knowledge and evidence on different types of psychological and neuropsychological interventions targeting mood and cognition. Findings will highlight important knowledge gaps and help prioritise future research questions. Systematic Review Registration This protocol was prospectively registered with the International Prospective Register of Systematic Reviews (PROSPERO) on November 15, 2022; PROSPERO CRD42022375947.

Published
2024
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5. Race, ethnicity and COVID-19 vaccination: a qualitative study of UK healthcare staff

Author

Dorothy Peprah, Anne Marie Rafferty, Stephani L. Hatch, Cerisse Gunasinghe, Ghazala Mir, Rebecca Rhead, Nathan Stanley, Paula Meriez, Juliana Onwumere, Zoe Chui, Jessica D. Jones Nielsen, Naomi Clifford, Hannah Harwood, Monalisa Bora-White, Charlotte Woodhead, and Luke Connor

Subjects
healthcare staff, Cultural Studies, COVID-19 Vaccines, Race, Ethnic group, HN, HM, Criminology, Power (social and political), 03 medical and health sciences, 0302 clinical medicine, Arts and Humanities (miscellaneous), RA0421, Health care, Ethnicity, Humans, 030212 general & internal medicine, Misinformation, Vaccine hesitancy, Minority Groups, Legitimacy, Vaccines, 030505 public health, business.industry, Vaccination, Public Health, Environmental and Occupational Health, COVID-19, Patient Acceptance of Health Care, United Kingdom, 3. Good health, Harm, QR180, ethnicity, 0305 other medical science, Psychology, business, discrimination, Qualitative research
Abstract

Objective: COVID-19-related inequities experienced by racial and ethnic minority groups including healthcare professionals mirror wider health inequities, which risk being perpetuated by lower uptake of vaccination. We aim to better understand lower uptake among racial and ethnic minority staff groups to inform initiatives to enhance uptake. Design: Twenty-five semi-structured interviews were conducted (October 2020–January 2021) with UK-based healthcare staff. Data were inductively and thematically analysed. Results: Vaccine decision-making processes were underpinned by an overarching theme, ‘weighing up risks of harm against potential benefits to self and others’. Sub-themes included ‘fear of harm’, ‘moral/ethical objections’, ‘potential benefits to self and others’, ‘information and misinformation’, and ‘institutional or workplace pressure’. We identified ways in which these were weighted more heavily towards vaccine hesitancy for racial and ethnic minority staff groups influenced by perceptions about institutional and structural discrimination. This included suspicions and fear around institutional pressure to be vaccinated, racial injustices in vaccine development and testing, religious or ethical concerns, and legitimacy and accessibility of vaccine messaging and communication. Conclusions: Drawing on a critical race perspective, we conclude that acknowledging historical and contemporary abuses of power is essential to avoid perpetuating and aggravating mistrust by de-contextualising hesitancy from the social processes affecting hesitancy, undermining efforts to increase vaccine uptake.

Published
2021
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6. OP35 Race, ethnicity and COVID-19 vaccination: a qualitative study of UK healthcare staff

Author

Rebecca Rhead, Ghazala Mir, Juliana Onwumere, Monalisa Bora-White, Cerisse Gunasinghe, Hannah Harwood, Charlotte Woodhead, Paula Meriez, Naomi Clifford, and Zoe Chui

Subjects
Vaccination, Power (social and political), Harm, business.industry, Health care, Ethnic group, Medicine, Misinformation, Criminology, business, Legitimacy, Qualitative research
Abstract

Background COVID-19-related inequities experienced by racial and ethnic minority groups including healthcare professionals mirror wider health inequities, which risk being perpetuated by lower uptake of vaccination. We aim to better understand lower uptake among racial and ethnic minority staff groups to inform initiatives to enhance uptake. Methods Twenty-five semi-structured interviews were conducted (October 2020-January 2021) with UK-based healthcare staff. Data were inductively and thematically analysed. Results Vaccine decision-making processes were underpinned by an overarching theme, ‘weighing up risks of harm against potential benefits to self and others’. Sub-themes included ‘fear of harm’, ‘moral/ethical objections’, ‘potential benefits to self and others’, ‘information and misinformation’, and ‘institutional or workplace pressure’. We identified ways in which these were weighted more heavily towards vaccine hesitancy for racial and ethnic minority staff groups influenced by perceptions about institutional and structural discrimination. This included suspicions and fear around institutional pressure to be vaccinated, racial injustices in vaccine development and testing, religious or ethical concerns, and legitimacy and accessibility of vaccine messaging and communication. Conclusion Drawing on a critical race perspective, we conclude that acknowledging historical and contemporary abuses of power is essential to avoid perpetuating and aggravating mistrust by de-contexualising hesitancy from the social processes affecting hesitancy, undermining efforts to increase vaccine uptake.

Published
2021
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7. 13 Park Lane

Author

Naomi Clifford and Naomi Clifford

Abstract

She found refuge as a cook in a London household—but even the grandest homes can hide terrible things...1872. Marguerite has fled to London, leaving behind a traumatic past in Paris. When she is offered work as a cook for mysterious French widow Madame Riel, she seizes the chance to start afresh. But as soon as Marguerite arrives, she is stifled by the tension in the house—and before long, she comes to resent her stingy and volatile employer, as well as the unfriendly housemaid. Just as Marguerite is about to resign, Madame Riel's beautiful daughter Julie, an actress, returns to the house and charms her into staying. But Julie's presence creates new toxic waves of emotion—until someone finally snaps. Why is 13 Park Lane so full of hatred? What secrets does the household guard? And can any of its inhabitants escape the shackles of their pasts?

Published
2024

8. The Murder of Mary Ashford : The Crime That Changed English Legal History

Author

Naomi Clifford and Naomi Clifford

Subjects
Trials (Murder)--England, Murder--England--Erdington
Abstract

Historical true crime comes to life with this fictionalized account of a nineteenth-century murder that changed the course of British legal history. England, 1817. In the small hours of May 27th, a young servant girl from the village of Erdington left a party in the company of a man with a bad reputation. A few hours later, Mary Ashford's lifeless body was found drowned in a pond. Despite a seemingly solid alibi, Abraham Thornton is soon on trial for his life—only to be acquitted at the direction of the judge. Public opinion across the country is outraged, with everyone convinced that a murderer has evaded the gallows. In a last-ditch effort to find justice, Mary's brother uses an archaic legal process to prosecute Thornton again, only to find himself confronted with an extraordinary challenge. In court, Thornton throws down a gauntlet and demands his legal right to trial by combat... and the outcome will alter the course of English legal history. A many-layered fictionalized account, The Murder of Mary Ashford examines the particulars of this famous case while exploring the birth of forensic investigation, the meaning of sexual consent, and the struggle of a modern state to emerge from its medieval heritage.

Published
2018

9. The Disappearance of Maria Glenn : A True Life Regency Mystery

Author

Naomi Clifford and Naomi Clifford

Subjects
Trials (Conspiracy)--History--19th century. --, Trials (Perjury)--History--19th century.--En, Abduction--Law and legislation--History--19t
Abstract

A kidnapping, an elopement gone wrong, and a sensational nineteenth-century trial are only the beginning of this Regency mystery. England, 1817. Barrister George Tuckett wakes to discover that his sixteen-year-old niece Maria Glenn, reputed heiress to West Indian sugar plantations, is missing. It seems she has been abducted by the Bowditches, a local farming family, who intend to force her to marry one of their sons. While Maria is ultimately rescued, the investigation that follows uncovers a complex and disturbing web of lies. At a drama-filled trial that is the talk of the country, four are sentenced to prison. When a cabal of powerful people begin a campaign to destroy Maria's testimony, her supporters fall away and she is openly vilified. Her enemies have her arrested for perjury, and soon she is forced to flee into exile. Yet the story of conspiracy and deception does not end there, as Maria and her uncle are to suffer one final and devastating betrayal... Deftly exploring the details of a case that had many in England taking sides, The Disappearance of Maria Glenn is an intriguing fictionalized account of a tawdry tale that will entice readers of both Regency romance and historical mystery.

Published
2016

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