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A 51-year-old Japanese man who experienced colon cancer recurrence following primary and metastatic lesion resection was hospitalized due to facial cellulitis with febrile neutropenia and purpura on his lower extremities after chemotherapy. It was complicated by rapidly progressive glomerulonephritis. He was diagnosed with immunoglobulin A (IgA)-dominant endocapillary proliferative glomerulonephritis based on kidney histology. His glomeruli were positive for the nephritis-associated plasmin receptor, plasmin activity and galactose-deficient IgA1 (Gd-IgA1). A skin biopsy immunofluorescence study revealed IgA deposition within perivascular regions but no Gd-IgA1 deposition. The final diagnosis was IgA-dominant infection-related glomerulonephritis (IRGN). The patient's renal function returned to normal after receiving immunosuppressive therapy that consisted of a glucocorticoid and a cyclophosphamide. Immunosuppressive therapy should be considered in cases of IRGN if the patient's infection is completely under control.

Pore pressure prediction is needed for drilling deepwater wildcats in the Sea of Japan because it is known from past experience that there can be drilling problems can arise due to overpressure at shallow depths. The “Joetsu Basin” area is located offshore to the southwest of Sado Island on the eastern margin of the Sea of Japan. The sedimentary succession of the Neogene is mainly composed of turbidite sediments which contained smectite-rich mudstones. The cause of overpressure in the study area is expected to be a combination of mechanical disequilibrium compaction and chemical compaction, especially from the illitization of smectite. We have constructed basin models and performed numerical simulations by using 1D and 3D PetroMod to understand clearly the history of fluid flow and overpressure development in the lower Pliocene Shiya Formation and Middle to Upper Miocene Teradomari Formations. A compaction model coupled with both mechanical and chemical compaction for smectite-rich sediments is used for pore pressure calibration. We have examined three key relationships: porosity-effective stress, porosity-permeability, and the kinetics of smectite-illite transformation. We determined the ranges for the parameter values in those relationships that allow a good fit between measured and modelled pore pressures to be obtained. Results showed that for the most likely case, high pore pressure in the Lower and Upper Teradomari developed since 8.5 Ma and 5.5 Ma, respectively. Pore pressures in studied structures have approximately doubled since 1 Ma due to the high deposition rate of the Pleistocene Haizume Formation and smectite-illite transformation in the lower Pliocene-Shiya and Middle to Upper Miocene- Lower and Upperr Teradomari formations. In three cases (high case, most likely case and low case), the overpressures in the Shiya, Upper and Lower Teradomari Formations are less than 1 MPa, 15 and 30 Ma, respectively. The results provide a basis for planning future wells in the “Joetsu Basin” area and in other basins where geological conditions are similar, i.e., deepwater, high sedimentation rate, high geothermal gradient and smectite-rich sediments.

The structural phase transitions of tellurium (Te) are investigated at pressures of up to 330 GPa at 298 K using an X-ray powder diffraction technique. In the experiments, it was found that the high-pressure bcc phase (Te-V) transitioned to the fcc phase (Te-VI) at 99 GPa, although a double hcp phase (dhcp) coexisted with the fcc phase. As the pressure was increased and decreased, the dhcp phase vanished at 255 and 100 GPa, respectively. These results suggest that the dhcp phase is metastable at 298 K and the structure of the highest-pressure phase of Te is fcc. The present results provide important information regarding the high-pressure behavior of group-16 elements.