135 results on '"Nantermet, Philippe G."'
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2. Recent Advances Toward Pain Therapeutics
3. Attenuation of scratch-induced reactive astrogliosis by novel EphA4 kinase inhibitors
4. Addition of zinc homoenoates to acetylenic esters and amides: a formal (3 + 2) cycloaddition
5. Neutralization of Pathogenic Fungi with Small-Molecule Immunotherapeutics
6. Synthesis of Complex Druglike Molecules by the Use of Highly Functionalized Bench-Stable Organozinc Reagents
7. Reaction: The Art of Synthetic Chemistry
8. Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group
9. Chapter 2 - Recent Advances Toward Pain Therapeutics
10. SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine p Ka in enzyme inhibition
11. Rapid P1 SAR of brain penetrant tertiary carbinamine derived BACE inhibitors
12. Modeling a Crowdsourced Definition of Molecular Complexity
13. Total synthesis of (+/-)-ginkgolide
14. Synthesis of novel taxoids
15. Strategies towards Improving the Pharmacokinetic Profile of ε‐Substituted Lysinol‐Derived HIV Protease Inhibitors
16. Stroke Therapy
17. ChemInform Abstract: A Facile Three-Step Synthesis of 1,2-Amino Alcohols Using the Ellman Homochiral tert-Butylsulfinamide.
18. SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine pKa in enzyme inhibition
19. Evolution of Tertiary Carbinamine BACE‐1 Inhibitors: Aβ Reduction in Rhesus CSF upon Oral Dosing
20. Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors
21. Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors
22. Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation
23. β-Secretase (BACE-1) inhibitors: Accounting for 10s loop flexibility using rigid active sites
24. Molecules that Changed the World. By K. C. Nicolaou and Tamsyn Montagnon.
25. Molecules that Changed the World. Von K. C. Nicolaou und Tamsyn Montagnon.
26. Discovery of Oxadiazoyl Tertiary Carbinamine Inhibitors of β-Secretase (BACE-1)
27. P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold
28. 9-Hydroxyazafluorenes and Their Use in Thrombin Inhibitors
29. Imidazole Acetic Acid TAFIa Inhibitors: SAR Studies Centered Around the Basic P′1 Group.
30. Discovery and Evaluation of Potent P1 Aryl Heterocycle-Based Thrombin Inhibitors
31. Imidazole acetic acid TAFIa inhibitors: SAR studies centered around the basic P 1 ′ group
32. Design and Synthesis of Potent and Selective Macrocyclic Thrombin Inhibitors.
33. Synthesis and Evaluation of Imidazole Acetic Acid Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor as Novel Antithrombotics
34. Unexpected enhancement of thrombin inhibitor potency with o -aminoalkylbenzylamides in the P1 position
35. Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. implementation of P3 pyridine N-Oxides to deliver an orally bioavailable series containing P1 N-Benzylamides
36. Potent thrombin inhibitors via a 20-membered ring olefin metathesis macrocyclization
37. ChemInform Abstract: Discovery of a Nonpeptidic Small Molecule Antagonist of the Human Platelet Thrombin Receptor (PAR‐1).
38. Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1)
39. Discovery and initial structure–Activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists
40. A facile three-step synthesis of 1,2-amino alcohols using the Ellman homochiral tert-butylsulfinamide
41. The total synthesis of (+)-Ginkgolide
42. ChemInform Abstract: Selective α1a Adrenergic Receptor Antagonists Based on 4-Aryl-3,4-dihydropyridine-2-ones.
43. The Total Synthesis of (±)-Ginkgolide B
44. Selective α1a adrenergic receptor antagonists based on 4-aryl-3,4-dihydropyridine-2-ones
45. In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia
46. ChemInform Abstract: Total Synthesis of (.+‐.)‐Ginkgolide B.
47. Total Synthesis of (±)-Ginkgolide B
48. P 2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold
49. Novel method for the loading of nucleophiles on multipin crowns
50. Imidazole acetic acid TAFIa inhibitors: SAR studies centered around the basic P1′ group
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