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The railway is an important sector of the economy of Georgia. Despite its small share in the gross domestic product of the country, its role in the socio-economic development of the country is large. "Georgian Railway" is the only railway operator in Georgia. The company mainly provides services related to cargo transportation and transports various types of cargo from Central Asia to the Black Sea. The Georgian Railways also provides passenger transport. The company has a vertically integrated business model, owning and managing tracks, stations, terminals, other railway infrastructure and rolling stock covering the entire railway system across Georgia. The main railway network of "Georgian Railways", together with the railway of Azerbaijan, forms the Caucasus Railway Corridor, which is a key segment of the Europe-Caucasus-Asia transport corridor (TRACECA). The main railway network of "Georgian Railways" is the shortest way connecting the Caspian Sea region and Central Asia with the Black Sea and the Mediterranean Sea. The mentioned location uniquely contributes to the positioning of Georgian Railways in the trade system of Europe, the Caspian Sea region and Central Asia. Therefore, its economic growth and sustainable development largely depends on the effective use of the potential of a transit country. In this regard, it is necessary for the railways to be able to offer profitable conditions to customers and their practical implementation, for which it is necessary to create a powerful modern infrastructure, which ensures guaranteed protection of cargoes, their fast transportation and reduction of transport costs. Priority is given to scientific and technological directions, which should expand the use of advanced inventions in railway transport and increase the competitiveness of Georgian transport services in the market. It is necessary to modernize the railways by planning innovative projects, which in turn are associated with large investments. Keywords: Management, transport, railway transport, competitiveness.

Georgia is a small state with the small territory and the small population, but the shortest road connecting Europe and Asia passes through its territory, which has been properly used since time immemorial, even from the Hellenic and Roman civilizations. Even when Georgia was advanced economically and politically in the Middle Ages and even when Georgia was part of the Russian Empire. It is used even today - even after gaining independence, but it seems to be insufficient. As a result, the share of transport in the GDP of Georgia is modest, and this is also against the background of a poor economy, while this branch of the economy can bring tangible results, especially if we take into account the status of the country as a maritime country, which many countries in the world do not have the luxury of. Today, the implementation strategy of railway transport development is focused on the development of investment-innovation projects of the country's economy. Priority is given to scientific-technological directions that should expand the use of advanced inventions in railway transport and increase the competitiveness of Georgian transport services in the world market. For the issue of economic evaluation of engineering solutions, one of the main components of the engineering process is the determination of the economic feasibility of engineering solutions. Any event and action in business will lose its meaning if it does not give an economic effect. Therefore, the practical implementation of each solution should be justified economically, that is, the expected financial results that can be obtained by implementing these measures should be calculated in advance. Keywords: Management, transport, railway transport, competitiveness.

Introduction: The elucidation of the mechanism of action of radon on antioxidant processes needs further research, however, based on the results of the experiment, it can be concluded that studies on experimental animals have shown that, while inhaling Tskhaltubo water, the phenomenon of hormesis develops. Methods: we placed 10 experimental animals (KM rats) in Radon contained mineral water spa`s sauna. Inhalation of radon-water was administered through the nose, for 10 minutes, once a day, in conditions of high humidity (about 90%) for 10 days. Results: Hormesis regulates oxidative processes in the brain due to the activation of antioxidants expressed in a decrease in existing epileptic seizures and is expressed in the activation of Na / K-ATPase and specific glutaminergic neurons of the "attack center" of the hypothalamus but also with the activation of the entire adaptive-compensatory system. Conclusion: Inhalation of radon contained water can be considered as a method of treatment with an anticonvulsant effect confirmed by experimental studies.

The article deals with the issues of error detection and correction in the second order bi-pulse code. The analysis of the code generation algorithm is carried out, based on which it is shown that the code has 4 allowed four-bit combinations. The article considers own resources of a code which allow detecting and correcting both single errors and packets of errors. It is shown that errors are detected with probability of 1 when one, two and three bits of the code combination are distorted, while the probability of their correction does not exceed 0.5, in the case of distortion of all four symbols, both detection and correction of errors is impossible. To increase the probability of error correction, it is proposed to use a well-known method based on determining the parity or oddness of the allowed combinations in separate fragments of a linear signal, a brief description of the method is given, its analysis is carried out in relation to this code. It is shown that the use of this method makes it possible to correct all single, paired and three-time errors, as well as to detect all four-time errors, on the basis of which it can be concluded that it significantly improves the correcting properties of the signal under consideration.

Objective: Impaired lipoprotein metabolism is a significant and modifiable risk factor for atherosclerotic cardiovascular disease. Aim: The aim of our study was to determine the diagnostic accuracy of lipid profile indices in young adults in Georgian population. Methods: Under our observation were 107 patients with ischemic heart disease, aged 18-45 years, From the St. John The Merciful Private Clinic contingent. Examination: anamnesis, cardiography, echocardiography, coronography, blood lipid metabolism. Total cholesterol (TC), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), Triglycerides (TG), mmol/L) and lipid indices -TC-HDL/HDL, TG /HDL, and LDL/HDL Results: With IHD for young adults, TC-HDL/HDL distinguished by good sensitivity and sufficient specificity, TG /HDL - bad sensitivity and very excellent specificity, LDL/HDL - sufficient sensitivity and good specificity, With IHD, for TC-HDL/HDL Cut off=2.29, for TG /HDL, cut off=2.76 and for LDL/HDL - 2.17 High lipid indices on these data indicate a high risk of ischemic heart disease. Conclusion: lipid indices TC-HDL/HDL, TG /HDL, and LDL/HDL can be used for the primary diagnosis of ischemic heart disease in young adults. Keywords: risk factors IHD, dyslipidemia.

Methods of plasma heating by electromagnetic waves, interaction of electro-magnetic waves with magnetoactive plasma, plasma turbulence and transport processes are investigated in the trap of the linear plasma device OMT2. An ultrahigh frequency (UHF) contactless method is used to fill the open magnetic trap by plasma. We propose a new method of open magnetic trap filling with plasma whereby plasma is injected in the trap along the magnetic field from an independent stationary UHF source. The source is located outside the trap and plasma formation in it takes place in the strongly nonuniform magnetic field, in the electron cyclotron resonance (ECR) regime by means of the UHF power. In this paper we study the efficiency of open magnetic trap filling by plasma and plasma low frequency (LF) oscillations in the trap.

The interaction of surface-active drugs with surfactants, used in the simulation of artificial membranes by direct and reversed micelles, mainly determines the transport of drugs in the body and the complex process of the binding to receptors. Besides, the delivery of drugs into the body via microemulsions has been successfully used to reduce the first-pass metabolism. The structure of mixed reverse microemulsions based on the ionic surfactant sodium bis(2-ethylhexyl)sulfosuccinate (AOT) and the cationic surface active drug promethazine hydrochloride (PMT) was studied spectroscopically in the infrared and UV-visible regions, as well as using electrical conductivity and dynamic light scattering. The release profile of PMT from AOT-based microemulsions was studied using cellulose dialysis bags. The introduction of PMT additive into the water pockets of reverse AOT micelles leads to: a) an increase in free water fraction and a decrease in bound water fraction; b) changing the chromatographic retention factors of the model compounds; c) insignificant influence on the values of the binding constant of optical probe o-nitroaniline with the head groups of AOT; d) quenching of water-induced percolation in electrical conductance of reverse AOT microemulsions; e) a slight decrease in the size of water droplets at the same values of the molar ratio of water/surfactant. The release of PMT from the aqueous system obeys Fick’s law of diffusion (n = 0.4852), and the release of PMT from microemulsions is based on non-Fickian or anomalous diffusion.