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Most simulations of food production in response to various climates to date have used simulations of the same crop over multiple years. This study evaluated the impact of projected climate on performance of rice-lentil-groundnut cropping sequence in New Alluvial Zone of West Bengal, India, using DSSAT model. The study period consisted of baseline (1980-2010), mid-century (2040-2069) and end-century (2070-2099). Advancement in days to anthesis (2-13 days) was simulated for rice during the future periods. For lentil and groundnut, average advancement in days to anthesis was 1 day. Days to maturity were shortened by 3-16 days for rice and 0-7 days for lentil. Nevertheless, for groundnut, the days to maturity were simulated to increase by 1-9 days. The impact on final biomass and yield was simulated with and without CO 2 fertilization, and the positive impact of CO 2 fertilization was prominent for all the three crops. When CO 2 fertilization effect was considered, the yield of rice was projected to increase by 11-32%. On the other hand, yield of lentil and groundnut was estimated to change by - 31 to - 12% and - 33 to + 8%, respectively. Enhanced CO 2 could mitigate the magnitude of yield reduction due to enhanced temperature. Rice was benefited due to the carryover effect of residue from preceding groundnut and, hence, could sustain the yield on a long term. The study could also quantify the uncertainty in simulation of yield due to selection of GCMs., (© 2021. ISB.)

The research portrays the fate of a new herbicide mixture of fomesafen and quizalofop-ethyl. The soil samples viz. red lateritic soil (A), coastal saline soil (B) and black soil (C) were fortified separately for fomesafen and quizalofop-ethyl at 0.5 (T1) and 1.0 mg kg -1 (T2) doses and incubated at 20, 30 and 40°C. A satisfactory mean recovery, precision and linearity proved that the methods were accurate. Both the herbicides followed first + first order kinetics. Higher persistence of fomesafen was observed in Soil C than Soil B and Soil A with 22.38-53.75 days half-life, whereas quizalofop-ethyl showed higher stability in Soil A than Soils B and C with half-life of 0.93-12.07 days. Both compounds showed faster rates of dissipation at increased temperature, irrespective of soil type. The current study will help to predict the effect of temperature on the dissipation of herbicides in different soil under real field scenario., (© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

The shock of Coronavirus Disease 2019 (COVID-19) has disrupted food systems worldwide. Such disruption, affecting multiple systems interfaces in smallholder agriculture, is unprecedented and needs to be understood from multi-stakeholder perspectives. The multiple loops of causality in the pathways of impact renders the system outcomes unpredictable. Understanding the nature of such unpredictable pathways is critical to identify present and future systems intervention strategies. Our study aims to explore the multiple pathways of present and future impact created by the pandemic and "Amphan" cyclonic storm on smallholder agricultural systems. Also, we anticipate the behaviour of the systems elements under different realistic scenarios of intervention. We explored the severity and multi-faceted impacts of the pandemic on vulnerable smallholder agricultural production systems through in-depth interactions with key players at the micro-level. It provided contextual information, and revealed critical insights to understand the cascading effect of the pandemic and the cyclone on farm households. We employed thematic analysis of in-depth interviews with multiple stakeholders in Sundarbans areas in eastern India, to identify the present and future systems outcomes caused by the pandemic, and later compounded by "Amphan". The immediate adaptation strategies of the farmers were engaging family labors, exchanging labors with neighbouring farmers, borrowing money from relatives, accessing free food rations, replacing dead livestock, early harvesting, and reclamation of waterbodies. The thematic analysis identified several systems elements, such as harvesting, marketing, labor accessibility, among others, through which the impacts of the pandemic were expressed. Drawing on these outputs, we employed Mental Modeler , a Fuzzy-Logic Cognitive Mapping tool, to develop multi-stakeholder mental models for the smallholder agricultural systems of the region. Analysis of the mental models indicated the centrality of "Kharif" (monsoon) rice production, current farm income, and investment for the next crop cycle to determine the pathways and degree of the dual impact on farm households. Current household expenditure, livestock, and soil fertility were other central elements in the shared mental model. Scenario analysis with multiple stakeholders suggested enhanced market access and current household income, sustained investment in farming, rapid improvement in affected soil, irrigation water and livestock as the most effective strategies to enhance the resilience of farm families during and after the pandemic. This study may help in formulating short and long-term intervention strategies in the post-pandemic communities, and the methodological approach can be used elsewhere to understand perturbed socioecological systems to formulate anticipatory intervention strategies based on collective wisdom of stakeholders., Competing Interests: The author declares that the research as well as the article is original in nature and does not have any conflict of interest., (© 2021 Elsevier Ltd. All rights reserved.)

This study compares thirteen rice-based cropping systems in the coastal part of West Bengal, India in terms of productivity, profitability, energetics, and emissions. Information on the crop management practices of these systems was collected on 60 farms through a questionnaire survey. Rice-bitter gourd system was observed to have the highest system yield (49.88 ± 4.34 tha-1yr-1) followed by rice-potato-ridge gourd (37.78 ± 2.77 tha-1yr-1) and rice-potato-pumpkin (36.84 ± 2.04 tha-1yr-1) systems. The rice-bitter gourd system also recorded the highest benefit:cost ratio (3.92 ± 0.061). The lowest system yield and economics were recorded in the rice-fallow-fallow system. Rice-sunflower system recorded highest specific energy (2.54 ± 0.102 MJkg-1), followed by rice-rice (2.14 ± 0.174 MJkg-1) and rice-fallow-fallow (1.91 ± 0.327 MJkg-1) systems, lowest being observed in the rice-bitter gourd (0.52 ± 0.290 MJkg-1) and rice-pointed gourd (0.52 ± 0.373 MJkg-1) systems. Yield-scaled GHGs (YSGHG) emission was highest (1.265 ± 0.29 t CO2eqt-1 system yield) for rice-fallow-fallow system and was lowest for rice-vegetable systems. To estimate the uncertainty of the YSGHG across different systems under study, Monte-Carlo Simulation was performed. It was observed that there was a 5% probability of recording YSGHG emission > 1.15 t CO2eqt-1 system yield from different cropping systems in the present experiment. Multiple system properties such as productivity, economics, energy, and emission from all rice-based systems taken together, the rice-vegetable system performed consistently well across parameters and may be practised for higher economic returns with judicious and sustainable utilization of resources in the coastal saline tracts of the region., Competing Interests: The authors have declared that no competing interests exist.

Background and Objectives: The relationship between allergic diseases and internalizing disorders has not been well characterized with regard to multiple allergic diseases or longitudinal study. The objective of this study was to examine the association between multiple allergic diseases in early childhood with validated measures of internalizing disorders in the school-age years., Methods: Children enrolled in the Cincinnati Childhood Allergy and Air Pollution Study underwent skin testing and examinations at ages 1, 2, 3, 4, and 7 years. At age 7, parents completed the Behavior Assessment System for Children, Second Edition (BASC-2), a validated measure of childhood behavior and emotion. The association between allergic diseases at age 4, including allergic rhinitis, allergic persistent wheezing, atopic dermatitis, and allergic sensitization, and BASC-2 internalizing, anxiety, and depression T scores at age 7 was examined by logistic and linear regression, adjusting for covariates., Results: The cohort included 546 children with complete information on allergic disease and BASC-2 outcomes. Allergic rhinitis at age 4 was significantly associated with elevated internalizing (adjusted odds ratio [aOR]: 3.2; 95% confidence interval [CI]: 1.8-5.8), anxiety (aOR: 2.0; 95% CI: 1.2-3.6), and depressive scores (aOR: 3.2; 95% CI: 1.7-6.5) at age 7. Allergic persistent wheezing was significantly associated with elevated internalizing scores (aOR: 2.7; 95% CI: 1.2-6.3). The presence of >1 allergic disease (aOR: 3.6; 95% CI: 1.7-7.6) and allergic rhinitis with comorbid allergic disease(s) (aOR: 4.3; 95% CI: 2.0-9.2) at age 4 had dose-dependent associations with internalizing scores., Conclusions: Children with allergic rhinitis and allergic persistent wheezing at age 4 are at increased risk of internalizing behaviors at age 7. Furthermore, multiple allergic diseases had a dose-dependent association with elevated internalizing scores., (Copyright © 2016 by the American Academy of Pediatrics.)

Background: There is a paucity of data that describe the clinical course of hereditary angioedema (HAE) in children., Objective: The purpose of this study was to examine the clinical features of children with HAE., Methods: Electronic medical records from the past 10 years at Cincinnati Children's Hospital Medical Center and an outpatient allergy community practice were searched for ICD-9 code 277.6 (Other deficiencies of circulating enzyme). Exclusion criteria included laboratory data not supportive of type I or II HAE diagnosis or age at diagnosis greater than 18 years. Chart review was performed and missing data were collected by telephone interviews with patient families. Descriptive statistics were performed using SAS version 9.4., Results: Twenty-one children were identified. The median age was 13.2 years (interquartile range [IQR], 9.1-18.8), 71% were male, 86% had an HAE family history, and 95% were Caucasian. The median age of symptom onset and diagnosis was 5.7 (IQR, 5-9 years) and 5.0 (IQR, 4-8 years), respectively. Five children diagnosed were asymptomatic. Three children without a family history had a 6.0-year delay in diagnosis. The most common angioedema attack sites were abdominal, peripheral, and laryngeal, which occurred at least once in 93%, 73%, and 27%, respectively. Of the 15 children with onset of symptoms, only 6 children received on-demand therapy for an acute attack, whereas 13 children were administered either short-term or long-term prophylaxis therapy., Conclusions: In this pediatric HAE population, symptom onset and diagnosis occurred at a median age of 5 years with a delay in diagnosis in those without a family history. Abdominal attacks were more common than peripheral attacks in this population., (Copyright © 2015 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.)

Background: Current guidelines recommend short-term prophylaxis (STP) before invasive procedures to prevent hereditary angioedema (HAE) attacks; however, adherence to these guidelines may be variable because this indication lacks Food and Drug Administration approval in the United States., Objective: To ascertain the STP experiences of patients with HAE and HAE-treating physicians., Methods: Online questionnaires focusing on STP experiences were distributed by the US Hereditary Angioedema Association to the first 250 patients with HAE and to registered HAE-treating physicians. SAS 9.3 was used to perform descriptive statistics and to test the difference between patients who underwent procedures and those who did not using Pearson χ(2) test, Fisher exact test, and 2-sample t test., Results: For the patient survey, 219 respondents met the criteria for HAE type 1 and 2; 37 (17%) underwent 66 invasive procedures, and all reported receiving STP. Eight patients (22%) reported failed STP, but only 3 required on-demand therapy. For STP, anabolic steroids and plasma-derived C1 inhibitor were the most and second-most commonly used, respectively. For the physician survey, 37 physicians reported caring for 433 patients with HAE. Depending on the procedure, 19% to 54% of physicians used STP and 30% to 86% prescribed on-demand therapy; 69% and 78% of physicians prescribed plasma-derived C1 inhibitor as STP for minimally invasive and invasive procedures, respectively. Physicians reported excellent efficacy for the STP treatments used., Conclusion: Physicians reported excellent outcomes using primarily newer STP therapies, namely plasma-derived C1 inhibitor, which was discordant to patient-reported outcomes using older STP therapies, namely anabolic steroids. Well-controlled STP studies are needed to clarify use for patients with HAE in the United States., (Copyright © 2014 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.)