1. Obesity-associated sleep hypoventilation and increased adverse postoperative bariatric surgery outcomes in a large clinical retrospective cohort
- Author
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Pornprapa Chindamporn, Lu Wang, James Bena, Alexander Zajichek, Alex Milinovic, Roop Kaw, Sangeeta R. Kashyap, Derrick Cetin, Ali Aminian, Nancy Kempke, Nancy Foldvary-Schaefer, Loutfi S. Aboussouan, and Reena Mehra
- Subjects
Pulmonary and Respiratory Medicine ,Male ,Bariatric Surgery ,Hypoventilation ,Carbon Dioxide ,Body Mass Index ,Neurology ,Obesity Hypoventilation Syndrome ,Humans ,Female ,Neurology (clinical) ,Obesity ,Sleep ,Retrospective Studies - Abstract
Although obesity hypoventilation syndrome (OHS) is associated with increased morbidity and mortality, post-bariatric surgery OHS risk remains unclear due to often nonsystematic OHS assessments.We leverage a clinical cohort with nocturnal COThe analytic sample (n = 1,665) was aged 45.2 ± 12 years, 20.4% were male, had a body mass index of 48.7 ± 9 kg/mIn this largest sample to date of systematically phenotyped OaSH in a bariatric surgery cohort, we identify increased postoperative morbidity in those with sleep-related hypoventilation in stage II OHS when a composite outcome was considered, but individual contributors of intubation, intensive care unit admission, and hospital length of stay were not increased. Further study is needed to identify whether perioperative treatment of OaSH improves post-bariatric surgery outcomes.Chindamporn P, Wang L, Bena J, et al. Obesity-associated sleep hypoventilation and increased adverse postoperative bariatric surgery outcomes in a large clinical retrospective cohort.
- Published
- 2022