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35 results on '"Namgung, Eun"'

7. Digital therapeutics using virtual reality‐based visual perceptual learning for visual field defects in stroke: A double‐blind randomized trial

Author

Namgung, Eun, primary, Kwon, Sun U., additional, Han, Moon‐Ku, additional, Kim, Gyeong‐Moon, additional, Kim, Hahn Young, additional, Park, Kwang‐Yeol, additional, Cho, Moonju, additional, Choi, Ha‐Gyun, additional, Nah, Hyun‐Wook, additional, Lim, Hyun Taek, additional, and Kang, Dong‐Wha, additional

Published
2024
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19. Repetitive transcranial magnetic stimulation in trauma-related conditions

Author

Namgung,Eun, Kim,Myeongju, and Yoon,Sujung

Subjects
Neuropsychiatric Disease and Treatment, mental disorders, behavioral disciplines and activities
Abstract

Eun Namgung,1,2,* Myeongju Kim,1,2,* Sujung Yoon1,2 1Department of Brain and Cognitive Sciences, Ewha Womans University, Seoul, South Korea; 2Ewha Brain Institute, Ewha Womans University, Seoul, South Korea *These authors contributed equally to this work Abstract: Some of trauma-exposed individuals develop posttraumatic stress disorder (PTSD), an incapacitating psychiatric disorder that is characterized by intrusion, avoidance, negative changes in mood and cognition, and hyperarousal. A number of other trauma-related conditions are very frequently found in individuals with PTSD. Traumatic brain injury (TBI) is one of the most frequently observed trauma-related conditions that trauma-exposed individuals with PTSD may experience. TBI refers to transient or permanent brain dysfunction that results in a wide range of neurological, cognitive, and psychiatric symptoms. These trauma-related conditions significantly affect one’s quality of life, leading to substantial disability and socioeconomic burden. As the prevalence of PTSD with comorbid TBI is increasing in the general population along with the rates of crimes and accidents, effective prevention and intervention strategies are necessitated. However, a definitive treatment for PTSD with comorbid TBI is still lacking, resulting in high rates of treatment resistance and chronicity. It is essential to investigate the neurobiological mechanisms and potential therapeutics of PTSD with comorbid TBI. Yet, a few repetitive transcranial magnetic stimulation (rTMS) studies have recently investigated therapeutic efficacy in treatment-resistant patients with PTSD and/or TBI. Thus, this article reviews rTMS studies in trauma-related conditions, mainly focusing on PTSD and PTSD with TBI as one of the comorbidities. The review focuses on the applications of rTMS in reducing PTSD symptoms with and without comorbidities based on differential parameters and effects of rTMS as well as concomitant clinical conditions. The section on PTSD with comorbidities focuses on TBI with neurological, cognitive, and psychiatric symptoms. Although there were some inconsistencies in the clinical outcomes and optimized parameters of rTMS applied in PTSD and TBI, low frequency stimulation over the hyperactive frontal regions and/or high frequency stimulation over the hypoactive frontal regions generally improved the clinical symptoms of PTSD and TBI. Lastly, the limitations of the rTMS studies in PTSD and TBI as well as potential directions for future research are discussed. Keywords: trauma, posttraumatic stress disorder, traumatic brain injury, repetitive transcranial magnetic stimulation, brain, neuromodulation

Published
2019

23. Effects of Korean red ginseng on human gray matter volume and cognitive function: A voxel‐based morphometry study.

Author

Namgung, Eun, Kim, Jungyoon, Jeong, Hyeonseok, Hong, Gahae, Kim, Myeongju, Kim, Rye Young, Kim, Shinhye, and Lyoo, In Kyoon

Subjects
*COGNITIVE ability, *GRAY matter (Nerve tissue), *VOXEL-based morphometry, *MAGNETIC resonance imaging, *GINSENG, *EXECUTIVE function
Abstract

Objective: We aimed to investigate the effects of Korean red ginseng (KRG) supplementation on gray matter volume of the human brain which could be related to cognitive enhancing effects of KRG. Methods: In this randomized, double‐blind, placebo‐controlled study, 51 healthy individuals were assigned to receive either KRG (1000 mg/day, n = 26) or placebo (n = 25) for 8 weeks. Gray matter volume of the whole brain was measured using voxel‐based morphometry based on high‐resolution T1‐weighted magnetic resonance images acquired at baseline and week 8. The standardized composite cognitive scores of executive function, attention, and memory were also evaluated at baseline and week 8. Changes in gray matter volume as well as the composite cognitive scores were compared between the KRG and placebo groups. Results: Following 8 weeks of KRG supplementation, the gray matter volume of the left parahippocampal gyrus increased significantly in the KRG group, relative to the placebo group (p for interaction < 0.001). The KRG group also showed greater magnitude of enhancement in the composite cognitive scores relative to the placebo group (p for interaction = 0.03). Conclusions: Gray matter volume increase in the parahippocampus may be a key neural change as induced by KRG supplementation, which could be associated with cognitive enhancement. [ABSTRACT FROM AUTHOR]

Published
2021
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24. Alterations in structural rich-club connectivity of the precuneus are associated with depressive symptoms among individuals with subjective memory complaints

Author

Kim, Geon Ha, primary, Kim, Jung Yoon, additional, Kim, Jieun E., additional, Ma, Jiyoung, additional, Kim, Bori R., additional, Im, Jooyeon Jamie, additional, Jeong, Hyeonseok S., additional, Namgung, Eun, additional, Lee, Suji, additional, Kang, Ilhyang, additional, Lyoo, In Kyoon, additional, Hwang, Jaeuk, additional, and Yoon, Sujung, additional

Published
2018
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25. Altered attentional control over the salience network in complex regional pain syndrome

Author

Kim, Jungyoon, primary, Kang, Ilhyang, additional, Chung, Yong-An, additional, Kim, Tae-Suk, additional, Namgung, Eun, additional, Lee, Suji, additional, Oh, Jin Kyoung, additional, Jeong, Hyeonseok S., additional, Cho, Hanbyul, additional, Kim, Myeong Ju, additional, Kim, Tammy D., additional, Choi, Soo Hyun, additional, Lim, Soo Mee, additional, Lyoo, In Kyoon, additional, and Yoon, Sujung, additional

Published
2018
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26. Brain structural changes in cynomolgus monkeys administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A longitudinal voxel-based morphometry and diffusion tensor imaging study

Author

Jeong, Hyeonseok S., primary, Lee, Sang-Rae, additional, Kim, Jieun E., additional, Lyoo, In Kyoon, additional, Yoon, Sujung, additional, Namgung, Eun, additional, Chang, Kyu-Tae, additional, Kim, Bom Sahn, additional, Yang, Sejung, additional, Im, Jooyeon J., additional, Jeon, Saerom, additional, Kang, Ilhyang, additional, Ma, Jiyoung, additional, Chung, Yong-An, additional, and Lim, Soo Mee, additional

Published
2018
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27. Network attributes underlying intellectual giftedness in the developing brain

Author

Ma, Jiyoung, primary, Kang, Hee Jin, additional, Kim, Jung Yoon, additional, Jeong, Hyeonseok S., additional, Im, Jooyeon Jamie, additional, Namgung, Eun, additional, Kim, Myeong Ju, additional, Lee, Suji, additional, Kim, Tammy D., additional, Oh, Jin Kyoung, additional, Chung, Yong-An, additional, Lyoo, In Kyoon, additional, Lim, Soo Mee, additional, and Yoon, Sujung, additional

Published
2017
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35. Customized Visual Discrimination Digital Therapy According to Visual Field Defects in Chronic Stroke Patients.

Author

Namgung E, Kim H, Kim YH, Kim YS, Lee EJ, Lee JH, Sasaki Y, Watanabe T, and Kang DW

Abstract

Background and Purpose: Visual perceptual learning (VPL) may improve visual field defects (VFDs) after chronic stroke, but the optimal training duration and location remain unknown. This prospective study aimed to determine the efficacy of 8 weeks of VFD-customized visual discrimination training in improving poststroke VFDs., Methods: Prospectively enrolled patients with poststroke VFDs initially received no training for 8 weeks (no-training phase). They subsequently underwent our customized VPL program that included orientation-discrimination tasks in individualized blind fields and central letter-discrimination tasks three times per week for 8 weeks (training phase). We analyzed the luminance detection sensitivity and deviation as measured using Humphrey visual field tests before and after the no-training and training phases. The vision-related quality of life was assessed at baseline and at a 16-week follow-up using the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25)., Results: Changes in mean total deviation (MTD) scores were greater during the training phase than during the no-training phase (defective hemifield, p =0.002; whole field, p =0.004). The MTD scores improved during the training phase (defective hemifield, p =0.004; whole field, p =0.016), but not during the no-training phase (defective hemifield, p =0.178; whole field, p =0.178). The difference between the improved and worsened areas (≥6 dB changes in luminance detection sensitivity) was greater during the training phase than during the no-training phase ( p =0.009). The vision-specific social functioning subscore of the NEI-VFQ-25 improved after the 16-week study period ( p =0.040)., Conclusions: Our 8-week VFD-customized visual discrimination training protocol may effectively improve VFDs and vision-specific social functioning in chronic stroke patients., Competing Interests: Eun-Jae Lee, a contributing editor of the Journal of Clinical Neurology, was not involved in the editorial evaluation or decision to publish this article. All remaining authors have declared no conflicts of interest., (Copyright © 2024 Korean Neurological Association.)

Published
2024
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