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Your search keyword '"Namaganda, Lukia H."' showing total 4 results
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4 results on '"Namaganda, Lukia H."'

1. Functioning and activity outcomes of the Akwenda Intervention Program for children and young adults with cerebral palsy in Uganda: A cluster‐randomized trial.

Author

Asige, Elizabeth, Saloojee, Gillian, Andrews, Carin, Namaganda, Lukia H., Kakooza‐Mwesige, Angelina, Damiano, Diane L., and Forssberg, Hans

Subjects
YOUNG adults, PEOPLE with cerebral palsy, CAREGIVERS, CEREBRAL palsy, SOCIAL interaction
Abstract

Aim: To evaluate the efficacy of the Akwenda Intervention Program on motor, self‐care, and social function of children and young people with cerebral palsy (CP). Method: This was a cluster‐randomized, controlled, single‐blinded, intervention study of 100 participants with CP (2–23 years; 52 males) in rural eastern Uganda. Half were allocated to the intervention program, the remainder served as waitlist controls. Gross Motor Function Measure‐66 (GMFM‐66) and the Ugandan version of Pediatric Evaluation of Disability Inventory (PEDI‐UG) were collected before group allocation and after intervention. General linear models and t‐tests were used to compare changes within and between groups. Cohen's d estimated the effect size of group differences. Change scores were evaluated by age and mobility subgroups. Results: Significant group by time interactions were found for GMFM‐66 (p =0.003) and PEDI‐UG outcomes (p <0.001), except mobility, with the intervention group demonstrating greater changes. Both groups increased their scores on the GMFM‐66 and child PEDI‐UG, while only the intervention group had significant increases in caregiver assistance scores and across all age and mobility subgroups. Cohen's d showed large effect sizes (d >0.8) of differences for PEDI‐UG outcomes except mobility. Interpretation: The Akwenda Intervention Program had a large positive impact on functioning and activity across age and mobility levels. [ABSTRACT FROM AUTHOR]

Published
2025
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4. Excessive premature mortality among children with cerebral palsy in rural Uganda : A longitudinal, population-based study

Author

Namaganda, Lukia H, Almeida, Rita, Kajungu, Dan, Wabwire-Mangen, Fred, Peterson, Stefan, Andrews, Carin, Eliasson, Ann Christin, Kakooza-Mwesige, Angelina, Forssberg, Hans, Namaganda, Lukia H, Almeida, Rita, Kajungu, Dan, Wabwire-Mangen, Fred, Peterson, Stefan, Andrews, Carin, Eliasson, Ann Christin, Kakooza-Mwesige, Angelina, and Forssberg, Hans

Abstract

BACKGROUND: Studies from high-income countries reported reduced life expectancy in children with cerebral palsy (CP), while no population-based study has evaluated mortality of children with CP in sub-Saharan Africa. This study aimed to estimate the mortality rate (MR) of children with CP in a rural region of Uganda and identify risk factors and causes of death (CODs). METHODS AND FINDINGS: This population-based, longitudinal cohort study was based on data from Iganga-Mayuge Health and Demographic Surveillance System in eastern Uganda. We identified 97 children (aged 2-17 years) with CP in 2015, whom we followed to 2019. They were compared with an age-matched cohort from the general population (n = 41 319). MRs, MR ratios (MRRs), hazard ratios (HRs), and immediate CODs were determined. MR was 3952 per 100 000 person years (95% CI 2212-6519) in children with CP and 137 per 100 000 person years (95% CI 117-159) in the general population. Standardized MRR was 25·3 in the CP cohort, compared with the general population. In children with CP, risk of death was higher in those with severe gross motor impairments than in those with milder impairments (HR 6·8; p = 0·007) and in those with severe malnutrition than in those less malnourished (HR = 3·7; p = 0·052). MR was higher in females in the CP cohort, with a higher MRR in females (53·0; 95% CI 26·4-106·3) than in males (16·3; 95% CI 7·2-37·2). Age had no significant effect on MR in the CP cohort, but MRR was higher at 10-18 years (39·6; 95% CI 14·2-110·0) than at 2-6 years (21·0; 95% CI 10·2-43·2). Anaemia, malaria, and other infections were the most common CODs in the CP cohort. CONCLUSIONS: Risk of premature death was excessively high in children with CP in rural sub-Saharan Africa, especially in those with severe motor impairments or malnutrition. While global childhood mortality has significantly decreased during recent decades, this observed excessive mortality is a hidden humanitarian crisis that needs to be address

Published
2020
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