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A visible-light-mediated direct α-oxygenation of N,N-dibenzylanilines to imides in the presence of [Acr+-Mes]BF4 as a metal-free photocatalyst and O2 as a green oxidant.

Herein, we report a substituent-controlled synthesis of 1,2-diketones and internal alkynes from terminal alkynes and arylboronic acids via α-stilbene radicals obtained from heteroleptic Cu(i) complexes under visible-light irradiation.

A visible-light-driven photoredox-catalyzed nonaqueous oxidative C-N cleavage of N,N-dibenzylanilines to 2° amides is reported. Further, we have applied this protocol on 2-(dibenzylamino)benzamide to afford quinazolinones with (NH4)2S2O8 as an additive. Mechanistic studies imply that the reaction might undergo in situ generation of α-amino radical to imine by C-N bond cleavage followed by the addition of superoxide ion to form amides.

Quinazolinones/benzothiadiazines were used as amidyl/aminyl radical precursors for cascade cyclizations via a photoredox-catalyzed proton-coupled electron transfer (PCET) process for the first time. A controlled synthesis of isoindole-fused quinazolinones/benzothiadiazines was carried out via quinazolinone amidyl/benzothiadiazine aminyl radical addition to the C-C triple bond under mild conditions. This transition-metal-free method provides an efficient and broad substrate scope for the synthesis of isoindole-fused quinazolinones/benzothiadiazines with step economy and atom efficiency.

An efficient approach for visible-light-induced chemoselective aerobic Cα–H oxidation of propargylamines via molecular oxygen as an oxidant using rose bengal as a photoredox catalyst is reported. The photochemical protocol was employed for the direct oxygenation of Cα–H 2-propynyl-tertiary amines to 2-ynamides and further cyclization of oxazolo[2,3-a]isoquinolinone derivatives from phenylpropynyltetrahydroisoquinoline was established.

An efficient synthesis of imides using metal-free photoredox-catalyzed direct α-oxygenation of

A visible-light-driven photoredox-catalyzed nonaqueous oxidative C-N cleavage of