Search

Your search keyword '"Nair, Gopinath Balakrish"' showing total 155 results
Start Over Author "Nair, Gopinath Balakrish"
155 results on '"Nair, Gopinath Balakrish"'

3. Vibrio cholerae O139 genomes provide a clue to why it may have failed to usher in the eighth cholera pandemic

Author

Ramamurthy, Thandavarayan, Pragasam, Agila Kumari, Taylor-Brown, Alyce, Will, Robert C., Vasudevan, Karthick, Das, Bhabatosh, Srivastava, Sunil Kumar, Chowdhury, Goutam, Mukhopadhyay, Asish K., Dutta, Shanta, Veeraraghavan, Balaji, Thomson, Nicholas R., Sharma, Naresh C., Nair, Gopinath Balakrish, Takeda, Yoshifumi, Ghosh, Amit, Dougan, Gordon, and Mutreja, Ankur

Published
2022
Full Text
View/download PDF

4. Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark

Author

Pinna, Nishal Kumar, Anjana, Ranjit Mohan, Saxena, Shruti, Dutta, Anirban, Gnanaprakash, Visvanathan, Rameshkumar, Gnanavadivel, Aswath, Sukumaran, Raghavan, Srividhya, Rani, Coimbatore Subramanian Shanthi, Radha, Venkatesan, Balasubramanyam, Muthuswamy, Pant, Archana, Nielsen, Trine, Jørgensen, Torben, Færch, Kristine, Kashani, Alireza, Silva, Maria Camila Alvarez, Vestergaard, Henrik, Hansen, Tue Haldor, Hansen, Torben, Arumugam, Manimozhiyan, Nair, Gopinath Balakrish, Das, Bhabatosh, Pedersen, Oluf, Mohan, Viswanathan, and Mande, Sharmila Shekhar

Published
2021
Full Text
View/download PDF

5. Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India

Author

Alvarez-Silva, Camila, Kashani, Alireza, Hansen, Tue Haldor, Pinna, Nishal Kumar, Anjana, Ranjit Mohan, Dutta, Anirban, Saxena, Shruti, Støy, Julie, Kampmann, Ulla, Nielsen, Trine, Jørgensen, Torben, Gnanaprakash, Visvanathan, Gnanavadivel, Rameshkumar, Sukumaran, Aswath, Rani, Coimbatore Subramanian Shanthi, Færch, Kristine, Radha, Venkatesan, Balasubramanyam, Muthuswamy, Nair, Gopinath Balakrish, Das, Bhabatosh, Vestergaard, Henrik, Hansen, Torben, Mande, Sharmila Shekhar, Mohan, Viswanathan, Arumugam, Manimozhiyan, and Pedersen, Oluf

Published
2021
Full Text
View/download PDF

8. Human Milk Microbiome of Healthy Indian Mothers is Dominated by Genus Pseudomonas.

Author

Dutta, Sourabh, Das, Bhabatosh, Ghosh, Tarini Shankar, Kumar, Shakti, Kaushal, Raj Kumari, Ray, Pallab, Suri, Vanita, and Nair, Gopinath Balakrish

Abstract

Background: The composition of the human milk microbiome is highly variable and multifactorial. Milk microbiota from various countries show striking differences. There is a paucity of data from healthy lactating Indian mothers. Research Aim: To describe the milk microbiota of healthy North Indian women, using a culture-independent, targeted metagenomic approach. Methods: We recruited exclusively breastfeeding mothers (N = 22) who had vaginally delivered full-term singleton infants in a tertiary care hospital less than 1 week previously and had not recently consumed systemic antibiotics. Milk samples (5 ml) were collected aseptically, and microbial deoxyribonucleic acid was extracted. Microbial composition and diversity were determined using a 454-pyrosequencing platform. Core genera were identified, and their relative abundances ranked. Heatmaps showing the variation of the ranked abundances and Shannon index were obtained using R. Results: Participants (all exclusively vegetarian) had a mean (SD) age of 27.2 (3.4) years, postnatal age of 3.9 (1.6) days and gestation 38 (1.2) weeks. The dominant phylum was Proteobacterium (relative abundance 84%) and dominant genus Pseudomonas (relative abundance 61.78%). Eleven species of Pseudomonas were identified, all generally considered nonpathogenic. Based on abundance patterns of the core genera, the milk samples could be grouped: (a) dominated by Pseudomonas with low diversity; (b) less Pseudomonas and high diversity; and (c) dominated by Pseudomonas but high diversity. All neonates were healthy and gaining weight well at 1 month of age. Conclusions: Healthy, lactating, vegetarian, North Indian women who deliver at term gestation and have no recent exposure to antibiotics, have a unique milk microbiome dominated by Pseudomonas. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

9. Vibrio cholerae O139 genomes provide a clue to why it may have failed to usher in the eighth cholera pandemic

Author

Ramamurthy, Thandavarayan, Pragasam, Agila Kumari, Taylor-Brown, Alyce, Will, Robert C, Vasudevan, Karthick, Das, Bhabatosh, Srivastava, Sunil Kumar, Chowdhury, Goutam, Mukhopadhyay, Asish K, Dutta, Shanta, Veeraraghavan, Balaji, Thomson, Nicholas R, Sharma, Naresh C, Nair, Gopinath Balakrish, Takeda, Yoshifumi, Ghosh, Amit, Dougan, Gordon, Mutreja, Ankur, Will, Robert C [0000-0002-4230-5182], Das, Bhabatosh [0000-0002-2447-5380], Chowdhury, Goutam [0000-0003-1830-1920], Thomson, Nicholas R [0000-0002-4432-8505], Mutreja, Ankur [0000-0002-1118-8075], Apollo - University of Cambridge Repository, and Dougan, Gordon [0000-0003-0022-965X]

Subjects
Cholera Toxin, Multidisciplinary, 45, 631/208/212/2306, 631/326/41/2529, 45/43, article, General Physics and Astronomy, General Chemistry, bacterial infections and mycoses, General Biochemistry, Genetics and Molecular Biology, Vibrio cholerae O139, Cholera, 692/699/255/1318, Humans, 631/326/41/2530, Pandemics, Vibrio cholerae
Abstract

Cholera is a life-threatening infectious disease that remains an important public health issue in several low and middle-income countries. In 1992, a newly identified O139 Vibrio cholerae temporarily displaced the O1 serogroup. No study has been able to answer why the potential eighth cholera pandemic (8CP) causing V. cholerae O139 emerged so successfully and then died out. We conducted a genomic study, including 330 O139 isolates, covering emergence of the serogroup in 1992 through to 2015. We noted two key genomic evolutionary changes that may have been responsible for the disappearance of genetically distinct but temporally overlapping waves (A-C) of O139. Firstly, as the waves progressed, a switch from a homogenous toxin genotype in wave-A to heterogeneous genotypes. Secondly, a gradual loss of antimicrobial resistance (AMR) with the progression of waves. We hypothesize that these two changes contributed to the eventual epidemiological decline of O139.

Published
2021

12. Vibrio fluvialis in patients with diarrhea, Kolkata, India

Author

Chowdhury, Goutam, Pazhani, Gururaja P., Dutta, Devarati, Guin, Sucharita, Dutta, Sanjucta, Ghosh, Santanu, Izumiya, Hidemasa, Asakura, Masahiro, Yamasaki, Shinji, Takeda, Yoshifumi, Arakawa, Eiji, Watanabe, Haruo, Mukhopadhyay, Asish K., Bhattacharya, Mihir K., Rajendran, K., Nair, Gopinath Balakrish, and Ramamurthy, Thandavarayan

Subjects
Cholera toxin -- Health aspects, Genes -- Health aspects, Diarrhea -- Health aspects, Infection -- Health aspects, Health
Abstract

Many members of the family Vibrionaceae cause diarrheal disease; among these, Vibrio cholerae O1/ O139 and V. parahaemolyticus are responsible for several epidemics and pandemics (1,2). In Indonesia, >20% of [...]

Published
2012
Full Text
View/download PDF

16. Prevalence and genetic profiling of virulence determinants of non-O157 Shiga toxin-producing Escherichia coli isolated from cattle, beef, and humans, Calcutta, India. (Research)

Author

Khan, Asis, Yamasaki, Shinji, Sato, Toshio, Ramamurthy, Thandavarayan, Pal, Amit, Datta, Simanti, Chowdhury, Nandini Roy, Das, Suresh Chandra, Sikdar, Asim, Tsukamoto, Teizo, Bhattacharya, Sujit Kumar, Takeda, Yoshifumi, and Nair, Gopinath Balakrish

Subjects
Escherichia coli -- Genetic aspects, Diarrhea -- Causes of, Virulence (Microbiology) -- Genetic aspects, Public health -- India, Beef cattle -- Health aspects, Beef -- Health aspects, India -- Health aspects
Abstract

We investigated the prevalence of Shiga toxin-producing Escherichia coli (STEC) in hospitalized diarrhea patients in Calcutta, India, as well as in healthy domestic cattle and raw beef samples collected from [...]

Published
2002

27. Novel Cholera Toxin Variant and ToxT Regulon in Environmental Vibrio mimicus Isolates: Potential Resources for the Evolution of Vibrio cholerae Hybrid Strains

Author

Neogi, Sucharit Basu, primary, Chowdhury, Nityananda, additional, Awasthi, Sharda Prasad, additional, Asakura, Masahiro, additional, Okuno, Kentaro, additional, Mahmud, Zahid Hayat, additional, Islam, Mohammad Sirajul, additional, Hinenoya, Atsushi, additional, Nair, Gopinath Balakrish, additional, and Yamasaki, Shinji, additional

Published
2019
Full Text
View/download PDF

28. Novel cholera toxin variant and ToxT regulon in environmentalVibrio mimicusstrains: potential resources for the evolution ofVibrio choleraehybrid strains

Author

Neogi, Sucharit Basu, primary, Chowdhury, Nityananda, additional, Awasthi, Sharda Prasad, additional, Asakura, Masahiro, additional, Mahmud, Zahid Hayat, additional, Islam, Mohammad Sirajul, additional, Hinenoya, Atsushi, additional, Nair, Gopinath Balakrish, additional, and Yamasaki, Shinji, additional

Published
2018
Full Text
View/download PDF

30. Emerging trends in the etiology of enteric pathogens as evidenced from an active surveillance of hospitalized diarrhoeal patients in Kolkata, India

Author

Nair, Gopinath Balakrish, Ramamurthy, Thandavarayan, Bhattacharya, Mihir Kumar, Krishnan, Triveni, Ganguly, Sandipan, Saha, Dhira Rani, Rajendran, Krishnan, Manna, Byomkesh, Ghosh, Mrinmoy, Okamoto, Keinosuke, and Takeda, Yoshifumi

Subjects
Drug resistance in microorganisms -- Research, Diarrhea -- Causes of -- Research -- Diagnosis, Health
Abstract

Background This study was conducted to determine the etiology of diarrhoea in a hospital setting in Kolkata. Active surveillance was conducted for 2 years on two random days per week by enrolling every fifth diarrhoeal patient admitted to the Infectious Diseases and Beliaghata General Hospital in Kolkata. Results Most of the patients (76.1%) had acute watery diarrhoea in association with vomiting (77.7%) and some dehydration (92%). Vibrio cholerae O1, Rotavirus and Giardia lamblia were the important causes of diarrhoea. Among Shigella spp, S. flexneri 2a and 3a serotypes were most predominantly isolated. Enteric viruses, EPEC and EAEC were common in children [less than]5 year age group. Atypical EPEC was comparatively higher than the typical EPEC. Multidrug resistance was common among V. cholerae O1 and Shigella spp including tetracycline and ciprofloxacin. Polymicrobial infections were common in all age groups and 27.9% of the diarrhoea patients had no potential pathogen. Conclusions Increase in V. cholerae O1 infection among [less than]2 years age group, resistance of V. cholerae O1 to tetracycline, rise of untypable S. flexnerii, higher proportion of atypical EPEC and G. lamblia and polymicrobial etiology are some of the emerging trends observed in this diarrhoeal disease surveillance., Authors: Gopinath Balakrish Nair (corresponding author) [1]; Thandavarayan Ramamurthy [1]; Mihir Kumar Bhattacharya [1]; Triveni Krishnan [1]; Sandipan Ganguly [1]; Dhira Rani Saha [1]; Krishnan Rajendran [1]; Byomkesh Manna [1]; [...]

Published
2010
Full Text
View/download PDF

31. Molecular Evidence of Clonal Vibrio parahaemolyticus Pandemic Strains

Author

Chowdhury, Nandini Roy, Chakraborty, Soumen, Ramamurthy, Thandavarayan, Nishibuchi, Mitsuaki, Yamasaki, Shinji, Takeda, Yoshifumi, and Nair, Gopinath Balakrish

Subjects
Vibrio infections -- Research, Bacterial genetics -- Research, Epidemics -- International aspects, Gel electrophoresis -- Usage, Bacterial infections -- Research
Abstract

The upsurge in worldwide incidence of Vibrio parahaemolyticus infection in the last 5 years has been attributed to the recent appearance of three serotypes with pandemic potential: O3:K6, O4:K68, and [...]

Published
2000

32. Multidrug-resistant Shigella dysenteriae type 1: forerunners of a new epidemic strain in eastern India? (Letters)

Author

Sur, Dipika, Niyogi, Swapan K., Sur, Shravani, Datta, Kamal K., Takeda, Yoshifumi, Nair, Gopinath Balakrish, and Bhattacharya, Sujit K.

Subjects
Market trend/market analysis, Shigellosis -- Analysis, Shigellosis -- Development and progression, Shigellosis -- Care and treatment, Communicable diseases -- Analysis, Communicable diseases -- Development and progression, Communicable diseases -- Care and treatment, Epidemiology -- Research, Drug resistance in microorganisms -- Forecasts and trends, Drug resistance in microorganisms -- Health aspects
Abstract

To the Editor: Multidrug-resistant Shigella dysenteriae type 1 caused an extensive epidemic of shigellosis in eastern India in 1984 (1). These strains were, however, sensitive to nalidixic acid, and clinicians [...]

Published
2003

34. Occurrence of Antibiotic Resistance Gene Cassettes aac(6′)-Ib, dfrA5, dfrA12, and ereA2 in Class I Integrons in Non-O1, Non-O139 Vibrio cholerae Strains in India

Author

Thungapathra, M., Amita, Sinha, Kislay K., Chaudhuri, Saumya Ray, Garg, Pallavi, Ramamurthy, Thandavarayan, Nair, Gopinath Balakrish, and Ghosh, Amit

Subjects
DNA, Bacterial, Reverse Transcriptase Polymerase Chain Reaction, Drug Resistance, Chromosome Mapping, India, Microbial Sensitivity Tests, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Ribotyping, Integrons, Blotting, Southern, Mechanisms of Resistance, DNA Transposable Elements, bacteria, Transformation, Bacterial, DNA Probes, Vibrio cholerae, Plasmids
Abstract

Molecular mechanisms of multidrug resistance in Vibrio cholerae belonging to non-O1, non-O139 serogroups isolated during 1997 to 1998 in Calcutta, India, were investigated. Out of the 94 strains examined, 22 strains were found to have class I integrons. The gene cassettes identified were dfrA1, dfrA15, dfrA5, and dfrA12 for trimethoprim; aac(6')-Ib for amikacin and tobramycin; aadA1 and aadA2 for streptomycin and spectinomycin; and ereA2 for erythromycin resistance. To our knowledge, this is the first report of the presence of dfrA5, dfrA12, aac(6')-Ib, and ereA2 cassettes in class I integrons of V. cholerae. Forty-three of 94 strains also had plasmids, and out of these, 14 contained both class I integrons and plasmids. Pulsed-field gel electrophoresis followed by Southern hybridization revealed that in the 14 plasmid-bearing strains, class I integrons resided either on chromosomes, on plasmids, or on both. Our results indicated that besides class I integrons and plasmids, a conjugative transposon element, SXT, possibly contributed to the multiple antibiotic resistance.

Published
2002

37. Vibrio fluvialisin Patients with Diarrhea, Kolkata, India

Author

Chowdhury, Goutam, primary, Pazhani, Gururaja P., additional, Dutta, Devarati, additional, Guin, Sucharita, additional, Dutta, Sanjucta, additional, Ghosh, Santanu, additional, Izumiya, Hidemasa, additional, Asakura, Masahiro, additional, Yamasaki, Shinji, additional, Takeda, Yoshifumi, additional, Arakawa, Eiji, additional, Watanabe, Haruo, additional, Mukhopadhyay, Asish K., additional, Bhattacharya, Mihir K., additional, Rajendran, K., additional, Nair, Gopinath Balakrish, additional, and Ramamurthy, Thandavarayan, additional

Published
2012
Full Text
View/download PDF

50. Variation of ToxigenicVibrio choleraeO1 in the Aquatic Environment of Bangladesh and Its Correlation with the Clinical Strains

Author

Islam, Mohammad Sirajul, primary, Talukder, Kaisar Ali, additional, Khan, Nurul Huda, additional, Mahmud, Zahid Hayat, additional, Rahman, Mohammed Ziaur, additional, Nair, Gopinath Balakrish, additional, Siddique, Abul K.M., additional, Yunus, Mohammad, additional, Sack, David Allen, additional, Sack, Richard Bradley, additional, Huq, Anwar, additional, and Colwell, Rita R., additional

Published
2004
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results