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311 results on '"Nahmias, Andre J."'

9. Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States

Author

Fujie Xu, Sternberg, Maya R., Kottiri, Benny J., McQuillan, Geraldine M., Lee, Francis K., Nahmias, Andre J., Berman, Stuart M., and Markowitz, Lauri E.

Subjects
Herpes simplex virus -- Diagnosis, Herpes genitalis -- Diagnosis
Abstract

The trends in Herpes simplex virus type 1 (HSV-1) and Herpes simplex virus type 2 (HSV-2) seroprevalence was examined in the US in 1999-2004 compared with 1988-1994. Findings revealed that the decline in HSV-2 suggested that the trajectory of increasing HSV-2 seroprevalence in the US is reversed and decrease in seroprevalence of HSV-1 but increase in the incidence of genital herpes caused by HSV-1.

Published
2006

12. Herpes simplex virus type 2 in the United States, 1976 to 1994

Author

Fleming, Douglas T., McQuillan, Geraldine M., Johnson, Robert E., Nahmias, Andre J., Aral, Sevgi O., Lee, Frances K., and St. Louis, Michael E.

Subjects
Herpes genitalis -- Statistics, Ethnic groups -- Health aspects
Abstract

The number of people infected with herpes simplex virus type 2 (HSV-2) has increased substantially since the late 1970's. Questionnaires were completed and blood samples were analyzed from 40,000 people aged 12 years and older during 1988 to 1994 and compared with data collected on 28,000 similar subjects during 1976 to 1980. The percentage of HSV-2-infected individuals rose by 30% between these two time periods. Individuals most likely to be infected were women, Mexican-Americans, blacks, and those who were poor, uneducated, sexually active with multiple partners, older, or who used cocaine.

Published
1997

13. Early progression of disease in HIV-infected infants with thymus dysfunction

Author

Kourtis, Athena P., Ibegbu, Christian, Nahmias, Andre J., Lee, Francis K., Clark, W. Scott, Sawyer, Mary K., and Nesheim, Steven

Subjects
HIV infection in children -- Physiological aspects, T cells -- Measurement, Infants -- Health aspects
Abstract

Infants infected with HIV at the time of birth may develop destruction of the thymus gland similar to that seen in babies with a congenital thymus disease called DiGeorge syndrome. Analysis of blood samples taken from 59 HIV-infected infants revealed that 17 had similar T cell profiles as 5 infants with the DiGeorge syndrome. The risk of acquiring AIDS in these 17 was much higher than in the remaining 42 HIV-infected infants. About half died within 6 months of their AIDS diagnosis, compared to only 7% of those without the abnormal T cell profile.

Published
1996

19. Underestimation of HSV-2 seroprevalence in a high-risk population by microneutralization assay

Author

Ashley, Rhoda L., Dalessio, Julie, Dragavon, Joan, Koutsky, Laura A., Lee, Francis K., Nahmias, Andre J., Stevens, Claire E., Holmes, King K., and Corey, Lawrence

Subjects
Herpes genitalis -- Diagnosis, Diagnostic virology -- Methods, Diagnostic reagents and test kits -- Evaluation, Health
Abstract

Complement independent neutralizing antibody assays (CINA) may not be an effective method for diagnosis of infections caused by herpes simplex virus type 2 (HSV-2). Infections caused by HSV-2 are usually transmitted sexually in genital secretions. A study evaluated blood samples from 521 women using a CINA and a Western blot assay. Seventy-six percent of the women had antibodies to HSV by CINA, compared with 81% by Western blot. Of 220 blood samples with antibodies to HSV-2 by Western blot, only 48% had neutralizing antibodies to HSV-2 by CINA. Evaluation using a CINA may miss a significant number of patients infected with HSV-2.

Published
1993

24. Changing Presentation of Herpes Simplex Virus Infection in Neonates

Author

NIAID Collaborative Antiviral Study Group, Whitley, Richard J., Corey, Lawrence, Arvin, Ann, Lakeman, Fred D., Sumaya, Ciro V., Wright, Peter F., Dunkle, Lisa M., Steele, Russell W., Soong, Seng-Jaw, Nahmias, Andre J., Alford, Charles A., Powell, Dwight A., and Joaquin, Vanusto San

Published
1988

38. Early diagnosis of HIV infection in infants by detection of IgA HIV antibodies

Author

Weiblen, Barbara J., Lee, Francis K., Cooper, Ellen R., Landesman, Sheldon H., McIntosh, Kenneth, Harris, Jo-Ann S., Nesheim, Steven, Mendez, Hermann, Pelton, Stephen I., Nahmias, Andre J., and Hoff, Rodney

Subjects
HIV infection -- Diagnosis, Immunoglobulin A -- Research, Immunoglobulin M -- Research, HIV (Viruses), Infants -- Diseases
Published
1990

39. A seroepidemiologic survey of the prevalence of herpes simplex virus type 2 infection in the United States

Author

Johnson, Robert E., Nahmias, Andre J., Magder, Laurence S., Lee, Francis K., Brooks, Camilla A., and Snowden, Cecelia B.

Subjects
Herpes simplex virus -- Demographic aspects, Serodiagnosis -- Analysis
Abstract

Herpes simplex virus type 2 (HSV-2), a sexually transmitted disease, can infect the genitals, mouth, skin or central nervous system. Transmission of the virus from a mother to her fetus, although uncommon, causes severe complications. The virus can remain inactive in the body or appear periodically and may or may not be visible. There is currently no cure, and there is some evidence that the infection predisposes patients to the human immunodeficiency virus (HIV). To determine the prevalence of the HSV-2 virus in the United States, 4,201 patients from 1976-1980 were screened. It can be estimated from these results that 16.4 percent of the U.S. population 15 to 74 years of age during that time was infected with the HSV-2 virus. Prevalence ranged from 1 percent in people under 15 (regardless of other factors) to 64.7 percent in blacks age 60-74 years. Black women had higher prevalence rates and the infection was more common in people previously married. The results of this study indicate that more people have the infection than originally expected and people may not necessarily have obvious symptoms.

Published
1989

42. Prolonged Dominance of Clonally Restricted CD4 + T Cells in Macaques Infected with Simian Immunodeficiency Viruses

Author

Chen, Zheng W., primary, Shen, Yun, additional, Kou, Zhongchen, additional, Ibegbu, Chris, additional, Zhou, Dejiang, additional, Shen, Ling, additional, Morrison, Paul, additional, Bogle, Christine, additional, McClure, Harold M., additional, Nahmias, Andre J., additional, Sehgal, Prahbat K., additional, and Letvin, Norman L., additional

Published
2000
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43. The disruption of macaque CD4 + T-cell repertoires during the early simian immunodeficiency virus infection

Author

Zhou, Dejiang, primary, Kou, ZhongChen, additional, Ibegbu, Chris, additional, Shen, Yun, additional, Lee-Parritz, David, additional, Shen, Ling, additional, Sehgal, Prabhat K., additional, McClure, Harold M., additional, Morrison, Paul, additional, Bogle, Christine, additional, Sehgal, Neetu, additional, Nahmias, Andre J., additional, and Chen, Zheng W., additional

Published
1999
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