1. Asymptomatic women at high risk of vertical HIV-1 transmission to their fetuses
- Author
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R. D'Ambrosio, B. Salassa, E. Palomba, Antonio Ponti, Cecilia Tibaldi, Alessandro Sinicco, Pier-Angelo Tovo, Mauro Sciandra, and Nahid Ziarati
- Subjects
medicine.medical_specialty ,Pregnancy ,Fetus ,business.industry ,Obstetrics ,Transmission (medicine) ,Lymphocyte ,Obstetrics and Gynecology ,General Medicine ,Odds ratio ,medicine.disease ,Asymptomatic ,medicine.anatomical_structure ,Acquired immunodeficiency syndrome (AIDS) ,Relative risk ,Immunology ,Gestation ,Medicine ,Viral disease ,medicine.symptom ,business ,Prospective cohort study - Abstract
Objective To identify how reliably CD4+ (helper) lymphocyte count and p24 antigenaemia can predict mother-to-infant transmission of human immunodeficiency virus type 1 (HIV-1). Design Prospective study. Setting University of Turin Center for Intravenous Drug Users (IVDU) and/or HIV-1 seropositive pregnant women. Subjects Twenty-nine infants born to asymptomatic seropositive women from November 1985 to June 1991. Results Seven children (24%) developed symptomatic infection, while 22 healthy seronegative children at the age of 18 months were considered uninfected. A CD4+ lymphocyte count persistently
- Published
- 1994
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