1,062 results on '"Nagase, Hiroshi"'
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2. Stimulation of kappa opioid receptors in the nucleus accumbens promotes feeding behavior in mice: Acute restoration of feeding during anorexia induced by 5-fluorouracil
3. Derived categories of NDG categories
4. KNT-127, a selective delta opioid receptor agonist, shows beneficial effects in the hippocampal dentate gyrus of a chronic vicarious social defeat stress mouse model
5. Role for μ-opioid receptor in antidepressant effects of δ-opioid receptor agonist KNT-127
6. Discovery of novel orexin receptor antagonists using a 1,3,5-trioxazatriquinane bearing multiple effective residues (TriMER) library
7. Morphinan derivatives with an oxabicyclo[3.2.1]octane structure as dual agonists toward δ and κ opioid receptors
8. Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors
9. Structural and Dynamic Insights into the Biased Signaling Mechanism of the Human Kappa Opioid Receptor
10. In silico design of novel probes for the atypical opioid receptor MRGPRX2
11. Derived categories of NDG categories
12. The delta opioid receptor agonist KNT‐127 relieves innate anxiety‐like behavior in mice by suppressing transmission from the prelimbic cortex to basolateral amygdala
13. Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation
14. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept
15. Systemic administration of a delta opioid receptor agonist, KNT-127, facilitates extinction learning of fear memory in rats
16. The delta opioid receptor agonist KNT‐127 relieves innate anxiety‐like behavior in mice by suppressing transmission from the prelimbic cortex to basolateral amygdala.
17. A delta opioid receptor agonist, KNT-127, in the prelimbic medial prefrontal cortex attenuates glial glutamate transporter blocker-induced anxiety-like behavior in mice
18. Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models
19. The application of a specific morphinan template to the synthesis of galanthamine
20. Deprotection of silyl ethers by using SO3H silica gel: Application to sugar, nucleoside, and alkaloid derivatives
21. Synthesis of heterocyclic compounds with adamantane-like cage structures consisting of phosphorus, sulfur, and carbon
22. Antitrichomonal activity of δ opioid receptor antagonists, 7-benzylidenenaltrexone derivatives
23. Gorenstein Projective Modules over Trivial Extension Rings
24. Design and synthesis of unique morphinan-type molecules: Their application to the search for the unexplored binding domain between opioid receptors and morphinan ligands
25. Asymmetric induction in cyclohexadienones carrying α-d-glucopyranosyl moiety
26. Administration of a delta opioid receptor agonist KNT-127 to the basolateral amygdala has robust anxiolytic-like effects in rats
27. Effects of the delta opioid receptor agonist KNT-127 on electroencephalographic activity in mice
28. Unexpected Rearrangement Reactions of the 14-Aminonaltrexone Skeleton
29. Design and Synthesis of Orexin 1 Receptor-Selective Agonists
30. Opioids in Preclinical and Clinical Trials
31. Synthesis of Novel Basic Skeletons Derived from Naltrexone
32. Design and synthesis of novel orexin 2 receptor agonists with a 1,3,5‑trioxazatriquinane skeleton
33. オピオイドδ受容体作動薬KNT-127による恐怖記憶の再固定化阻害作用およびその作用部位探索
34. Possibility of uncoupling protein 1 expression in bovine fast-twitch muscle fibers
35. Irritable bowel syndrome (IBS)-like symptoms in chronic vicarious social defeat stress model of mice are improved by the selected delta opioid receptor agonist KNT-127
36. Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: Part 5, novel pentacyclic propellane derivatives with a 6-amide side chain
37. Transformation of naltrexone into mesembrane and investigation of the binding properties of its intermediate derivatives to opioid receptors
38. Design and synthesis of orexin 1 receptor-selective agonists
39. Nonpeptide Orexin-2 Receptor Agonist Attenuates Morphine-induced Sedative Effects in Rats
40. Rational Drug Design of δ Opioid Receptor Agonist TAN-67 from δ Opioid Receptor Antagonist NTI
41. The most effective influence of 17-(3-ethoxypropyl) substituent on the binding affinity and the agonistic activity in KNT-127 derivatives, δ opioid receptor agonists
42. OX2R-selective orexin agonism is sufficient to ameliorate cataplexy and sleep/wake fragmentation without inducing drug-seeking behavior in mouse model of narcolepsy
43. Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton having a 7-amide side chain and their pharmacologies
44. Synthesis of quinolinomorphinan derivatives as highly selective δ opioid receptor ligands
45. Discovery of orexin 2 receptor selective and dual orexin receptor agonists based on the tetralin structure: Switching of receptor selectivity by chirality on the tetralin ring
46. Essential structure of orexin 1 receptor antagonist YNT-707: Conversion of the 16-cyclopropylmethyl group to the 16-sulfonamide group in d-nor-nalfurafine derivatives
47. Design and synthesis of novel orexin 2 receptor agonists based on naphthalene skeleton
48. Effect of removal of the 14-hydroxy group on the affinity of the 4,5-epoxymorphinan derivatives for orexin and opioid receptors
49. Synthesis of quinolinomorphinan-4-ol derivatives as δ opioid receptor agonists
50. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept
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